The following MYL2 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MYL2 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 501bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||myosin regulatory light chain 2, ventricular/cardiac muscle isoform
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AA090235.1, BC015821.1 and
This sequence is a reference standard in the RefSeqGene project.
On Jun 14, 2008 this sequence version replaced gi:94981552.
Summary: Thus gene encodes the regulatory light chain associated
with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the
phosphorylation of regulatory light chain that in turn triggers
contraction. Mutations in this gene are associated with mid-left
ventricular chamber type hypertrophic cardiomyopathy. [provided by
RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BP318509.1, BC031008.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: full length.