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NBN cDNA ORF clone, Homo sapiens (human)

Gene Symbol NBN
Entrez Gene ID 4683
Full Name nibrin
Synonyms AT-V1, AT-V2, ATV, NBS, NBS1, P95
General protein information
Preferred Names
nibrin
Names
nibrin
cell cycle regulatory protein p95
Nijmegen breakage syndrome 1 (nibrin)
p95 protein of the MRE11/RAD50 complex
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

8

8q21

Summary Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

602667

Disorder Html: Nijmegen breakage syndrome, 251260 (3); Leukemia, acute

mRNA and Protein(s)

mRNA Protein Name
XM_011517044 XP_011515346 nibrin isoform X1
XM_011517045 XP_011515347 nibrin isoform X2
XM_011517046 XP_011515348 nibrin isoform X3
NM_002485 NP_002476 nibrin
NM_001024688 NP_001019859 nibrin isoform 2



Homo sapiens (human) NBN NP_002476.2
Pan troglodytes (chimpanzee) NBN XP_519851.3
Macaca mulatta (Rhesus monkey) NBN XP_001085033.1
Canis lupus familiaris (dog) NBN XP_005638161.1
Bos taurus (cattle) NBN NP_001069305.2
Mus musculus (house mouse) Nbn NP_038780.3
Rattus norvegicus (Norway rat) Nbn NP_620228.1
Gallus gallus (chicken) NBN NP_989668.1
Danio rerio (zebrafish) nbn NP_001014819.1
Xenopus (Silurana) tropicalis (western clawed frog) nbn XP_004915210.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following NBN gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NBN cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu59211 XM_011517044 PREDICTED: Homo sapiens nibrin (NBN), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $391.30
$559.00
OHu42449 XM_011517045 PREDICTED: Homo sapiens nibrin (NBN), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $391.30
$559.00
OHu59212 XM_011517046 PREDICTED: Homo sapiens nibrin (NBN), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu25559
NM_002485 Homo sapiens nibrin (NBN), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$189.50-$265.30
$379.00
OHu42449 NM_001024688 Homo sapiens nibrin (NBN), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $391.30
$559.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu59211
Clone ID Related Accession (Same CDS sequence) XM_011517044
Accession Version XM_011517044.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2241bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product nibrin isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008046.17) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGGACTGGC AGGGAGAACC ATACAGACTT TTGACTGGCG TTGAGTACGT TGTTGGAAGG 
AAAAACTGTG CCATTCTGAT TGAAAATGAT CAGTCGATCA GCCGAAATCA TGCTGTGTTA
ACTGCTAACT TTTCTGTAAC CAACCTGAGT CAAACAGATG AAATCCCTGT ATTGACATTA
AAAGATAATT CTAAGTATGG TACCTTTGTT AATGAGGAAA AAATGCAGAA TGGCTTTTCC
CGAACTTTGA AGTCGGGGGA TGGTATTACT TTTGGAGTGT TTGGAAGTAA ATTCAGAATA
GAGTATGAGC CTTTGGTTGC ATGCTCTTCT TGTTTAGATG TCTCTGGGAA AACTGCTTTA
AATCAAGCTA TATTGCAACT TGGAGGATTT ACTGTAAACA ATTGGACAGA AGAATGCACT
CACCTTGTCA TGGTATCAGT GAAAGTTACC ATTAAAACAA TATGTGCACT CATTTGTGGA
CGTCCAATTG TAAAGCCAGA ATATTTTACT GAATTCCTGA AAGCAGTTGA GTCCAAGAAG
CAGCCTCCAC AAATTGAAAG TTTTTACCCA CCTCTTGATG AACCATCTAT TGGAAGTAAA
AATGTTGATC TGTCAGGACG GCAGGAAAGA AAACAAATCT TCAAAGGGAA AACATTTATA
TTTTTGAATG CCAAACAGCA TAAGAAATTG AGTTCCGCAG TTGTCTTTGG AGGTGGGGAA
GCTAGGTTGA TAACAGAAGA GAATGAAGAA GAACATAATT TCTTTTTGGC TCCGGGAACG
TGTGTTGTTG ATACAGGAAT AACAAACTCA CAGACCTTAA TTCCTGACTG TCAGAAGAAA
TGGATTCAGT CAATAATGGA TATGCTCCAA AGGCAAGGTC TTAGACCTAT TCCTGAAGCA
GAAATTGGAT TGGCGGTGAT TTTCATGACT ACAAAGAATT ACTGTGATCC TCAGGGCCAT
CCCAGTACAG GATTAAAGAC AACAACTCCA GGACCAAGCC TTTCACAAGG CGTGTCAGTT
GATGAAAAAC TAATGCCAAG CGCCCCAGTG AACACTACAA CATACGTAGC TGACACAGAA
TCAGAGCAAG CAGATACATG GGATTTGAGT GAAAGGCCAA AAGAAATCAA AGTCTCCAAA
ATGGAACAAA AATTCAGAAT GCTTTCACAA GATGCACCCA CTGTAAAGGA GTCCTGCAAA
ACAAGCTCTA ATAATAATAG TATGGTATCA AATACTTTGG CTAAGATGAG AATCCCAAAC
TATCAGCTTT CACCAACTAA ATTGCCAAGT ATAAATAAAA GTAAAGATAG GGCTTCTCAG
CAGCAGCAGA CCAACTCCAT CAGAAACTAC TTTCAGCCGT CTACCAAAAA AAGGGAAAGG
GATGAAGAAA ATCAAGAAAT GTCTTCATGC AAATCAGCAA GAATAGAAAC GTCTTGTTCT
CTTTTAGAAC AAACACAACC TGCTACACCC TCATTGTGGA AAAATAAGGA GCAGCATCTA
TCTGAGAATG AGCCTGTGGA CACAAACTCA GACAATAACT TATTTACAGA TACAGATTTA
AAATCTATTG TGAAAAATTC TGCCAGTAAA TCTCATGCTG CAGAAAAGCT AAGATCAAAT
AAAAAAAGGG AAATGGATGA TGTGGCCATA GAAGATGAAG TATTGGAACA GTTATTCAAG
GACACAAAAC CAGAGTTAGA AATTGATGTG AAAGTTCAAA AACAGGAGGA AGATGTCAAT
GTTAGAAAAA GGCCAAGGAT GGATATAGAA ACAAATGACA CTTTCAGTGA TGAAGCAGTA
CCAGAAAGTA GCAAAATATC TCAAGAAAAT GAAATTGGGA AGAAACGTGA ACTCAAGGAA
GACTCACTAT GGTCAGCTAA AGAAATATCT AACAATGACA AACTTCAGGA TGATAGTGAG
ATGCTTCCAA AAAAGCTGTT ATTGACTGAA TTTAGATCAC TGGTGATTAA AAACTCTACT
TCCAGAAATC CATCTGGCAT AAATGATGAT TATGGTCAAC TAAAAAATTT CAAGAAATTC
AAAAAGGTCA CATATCCTGG AGCAGGAAAA CTTCCACACA TCATTGGAGG ATCAGATCTA
ATAGCTCATC ATGCTCGAAA GAATACAGAA CTAGAAGAGT GGCTAAGGCA GGAAATGGAG
GTACAAAATC AACATGCAAA AGAAGAGTCT CTTGCTGATG ATCTTTTTAG ATACAATCCT
TATTTAAAAA GGAGAAGATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011515346.1
CDS16..2256
Misc Feature(1)28..318(+)
Misc Feature(2)73..216(+)
Misc Feature(3)331..537(+)
Misc Feature(4)367..405(+)
Misc Feature(5)517..531(+)
Misc Feature(6)2035..2229(+)
Translation

Target ORF information:

RefSeq Version XM_011517044
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens nibrin (NBN), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011517044

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGGACTGGC AGGGAGAACC ATACAGACTT TTGACTGGCG TTGAGTACGT TGTTGGAAGG 
AAAAACTGTG CCATTCTGAT TGAAAATGAT CAGTCGATCA GCCGAAATCA TGCTGTGTTA
ACTGCTAACT TTTCTGTAAC CAACCTGAGT CAAACAGATG AAATCCCTGT ATTGACATTA
AAAGATAATT CTAAGTATGG TACCTTTGTT AATGAGGAAA AAATGCAGAA TGGCTTTTCC
CGAACTTTGA AGTCGGGGGA TGGTATTACT TTTGGAGTGT TTGGAAGTAA ATTCAGAATA
GAGTATGAGC CTTTGGTTGC ATGCTCTTCT TGTTTAGATG TCTCTGGGAA AACTGCTTTA
AATCAAGCTA TATTGCAACT TGGAGGATTT ACTGTAAACA ATTGGACAGA AGAATGCACT
CACCTTGTCA TGGTATCAGT GAAAGTTACC ATTAAAACAA TATGTGCACT CATTTGTGGA
CGTCCAATTG TAAAGCCAGA ATATTTTACT GAATTCCTGA AAGCAGTTGA GTCCAAGAAG
CAGCCTCCAC AAATTGAAAG TTTTTACCCA CCTCTTGATG AACCATCTAT TGGAAGTAAA
AATGTTGATC TGTCAGGACG GCAGGAAAGA AAACAAATCT TCAAAGGGAA AACATTTATA
TTTTTGAATG CCAAACAGCA TAAGAAATTG AGTTCCGCAG TTGTCTTTGG AGGTGGGGAA
GCTAGGTTGA TAACAGAAGA GAATGAAGAA GAACATAATT TCTTTTTGGC TCCGGGAACG
TGTGTTGTTG ATACAGGAAT AACAAACTCA CAGACCTTAA TTCCTGACTG TCAGAAGAAA
TGGATTCAGT CAATAATGGA TATGCTCCAA AGGCAAGGTC TTAGACCTAT TCCTGAAGCA
GAAATTGGAT TGGCGGTGAT TTTCATGACT ACAAAGAATT ACTGTGATCC TCAGGGCCAT
CCCAGTACAG GATTAAAGAC AACAACTCCA GGACCAAGCC TTTCACAAGG CGTGTCAGTT
GATGAAAAAC TAATGCCAAG CGCCCCAGTG AACACTACAA CATACGTAGC TGACACAGAA
TCAGAGCAAG CAGATACATG GGATTTGAGT GAAAGGCCAA AAGAAATCAA AGTCTCCAAA
ATGGAACAAA AATTCAGAAT GCTTTCACAA GATGCACCCA CTGTAAAGGA GTCCTGCAAA
ACAAGCTCTA ATAATAATAG TATGGTATCA AATACTTTGG CTAAGATGAG AATCCCAAAC
TATCAGCTTT CACCAACTAA ATTGCCAAGT ATAAATAAAA GTAAAGATAG GGCTTCTCAG
CAGCAGCAGA CCAACTCCAT CAGAAACTAC TTTCAGCCGT CTACCAAAAA AAGGGAAAGG
GATGAAGAAA ATCAAGAAAT GTCTTCATGC AAATCAGCAA GAATAGAAAC GTCTTGTTCT
CTTTTAGAAC AAACACAACC TGCTACACCC TCATTGTGGA AAAATAAGGA GCAGCATCTA
TCTGAGAATG AGCCTGTGGA CACAAACTCA GACAATAACT TATTTACAGA TACAGATTTA
AAATCTATTG TGAAAAATTC TGCCAGTAAA TCTCATGCTG CAGAAAAGCT AAGATCAAAT
AAAAAAAGGG AAATGGATGA TGTGGCCATA GAAGATGAAG TATTGGAACA GTTATTCAAG
GACACAAAAC CAGAGTTAGA AATTGATGTG AAAGTTCAAA AACAGGAGGA AGATGTCAAT
GTTAGAAAAA GGCCAAGGAT GGATATAGAA ACAAATGACA CTTTCAGTGA TGAAGCAGTA
CCAGAAAGTA GCAAAATATC TCAAGAAAAT GAAATTGGGA AGAAACGTGA ACTCAAGGAA
GACTCACTAT GGTCAGCTAA AGAAATATCT AACAATGACA AACTTCAGGA TGATAGTGAG
ATGCTTCCAA AAAAGCTGTT ATTGACTGAA TTTAGATCAC TGGTGATTAA AAACTCTACT
TCCAGAAATC CATCTGGCAT AAATGATGAT TATGGTCAAC TAAAAAATTT CAAGAAATTC
AAAAAGGTCA CATATCCTGG AGCAGGAAAA CTTCCACACA TCATTGGAGG ATCAGATCTA
ATAGCTCATC ATGCTCGAAA GAATACAGAA CTAGAAGAGT GGCTAAGGCA GGAAATGGAG
GTACAAAATC AACATGCAAA AGAAGAGTCT CTTGCTGATG ATCTTTTTAG ATACAATCCT
TATTTAAAAA GGAGAAGATA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu42449
Clone ID Related Accession (Same CDS sequence) NM_001024688 , XM_011517045
Accession Version XM_011517045.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2019bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product nibrin isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008046.17) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGCAGAATG GCTTTTCCCG AACTTTGAAG TCGGGGGATG GTATTACTTT TGGAGTGTTT 
GGAAGTAAAT TCAGAATAGA GTATGAGCCT TTGGTTGCAT GCTCTTCTTG TTTAGATGTC
TCTGGGAAAA CTGCTTTAAA TCAAGCTATA TTGCAACTTG GAGGATTTAC TGTAAACAAT
TGGACAGAAG AATGCACTCA CCTTGTCATG GTATCAGTGA AAGTTACCAT TAAAACAATA
TGTGCACTCA TTTGTGGACG TCCAATTGTA AAGCCAGAAT ATTTTACTGA ATTCCTGAAA
GCAGTTGAGT CCAAGAAGCA GCCTCCACAA ATTGAAAGTT TTTACCCACC TCTTGATGAA
CCATCTATTG GAAGTAAAAA TGTTGATCTG TCAGGACGGC AGGAAAGAAA ACAAATCTTC
AAAGGGAAAA CATTTATATT TTTGAATGCC AAACAGCATA AGAAATTGAG TTCCGCAGTT
GTCTTTGGAG GTGGGGAAGC TAGGTTGATA ACAGAAGAGA ATGAAGAAGA ACATAATTTC
TTTTTGGCTC CGGGAACGTG TGTTGTTGAT ACAGGAATAA CAAACTCACA GACCTTAATT
CCTGACTGTC AGAAGAAATG GATTCAGTCA ATAATGGATA TGCTCCAAAG GCAAGGTCTT
AGACCTATTC CTGAAGCAGA AATTGGATTG GCGGTGATTT TCATGACTAC AAAGAATTAC
TGTGATCCTC AGGGCCATCC CAGTACAGGA TTAAAGACAA CAACTCCAGG ACCAAGCCTT
TCACAAGGCG TGTCAGTTGA TGAAAAACTA ATGCCAAGCG CCCCAGTGAA CACTACAACA
TACGTAGCTG ACACAGAATC AGAGCAAGCA GATACATGGG ATTTGAGTGA AAGGCCAAAA
GAAATCAAAG TCTCCAAAAT GGAACAAAAA TTCAGAATGC TTTCACAAGA TGCACCCACT
GTAAAGGAGT CCTGCAAAAC AAGCTCTAAT AATAATAGTA TGGTATCAAA TACTTTGGCT
AAGATGAGAA TCCCAAACTA TCAGCTTTCA CCAACTAAAT TGCCAAGTAT AAATAAAAGT
AAAGATAGGG CTTCTCAGCA GCAGCAGACC AACTCCATCA GAAACTACTT TCAGCCGTCT
ACCAAAAAAA GGGAAAGGGA TGAAGAAAAT CAAGAAATGT CTTCATGCAA ATCAGCAAGA
ATAGAAACGT CTTGTTCTCT TTTAGAACAA ACACAACCTG CTACACCCTC ATTGTGGAAA
AATAAGGAGC AGCATCTATC TGAGAATGAG CCTGTGGACA CAAACTCAGA CAATAACTTA
TTTACAGATA CAGATTTAAA ATCTATTGTG AAAAATTCTG CCAGTAAATC TCATGCTGCA
GAAAAGCTAA GATCAAATAA AAAAAGGGAA ATGGATGATG TGGCCATAGA AGATGAAGTA
TTGGAACAGT TATTCAAGGA CACAAAACCA GAGTTAGAAA TTGATGTGAA AGTTCAAAAA
CAGGAGGAAG ATGTCAATGT TAGAAAAAGG CCAAGGATGG ATATAGAAAC AAATGACACT
TTCAGTGATG AAGCAGTACC AGAAAGTAGC AAAATATCTC AAGAAAATGA AATTGGGAAG
AAACGTGAAC TCAAGGAAGA CTCACTATGG TCAGCTAAAG AAATATCTAA CAATGACAAA
CTTCAGGATG ATAGTGAGAT GCTTCCAAAA AAGCTGTTAT TGACTGAATT TAGATCACTG
GTGATTAAAA ACTCTACTTC CAGAAATCCA TCTGGCATAA ATGATGATTA TGGTCAACTA
AAAAATTTCA AGAAATTCAA AAAGGTCACA TATCCTGGAG CAGGAAAACT TCCACACATC
ATTGGAGGAT CAGATCTAAT AGCTCATCAT GCTCGAAAGA ATACAGAACT AGAAGAGTGG
CTAAGGCAGG AAATGGAGGT ACAAAATCAA CATGCAAAAG AAGAGTCTCT TGCTGATGAT
CTTTTTAGAT ACAATCCTTA TTTAAAAAGG AGAAGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011515347.1
CDS290..2308
Misc Feature(1)383..589(+)
Misc Feature(2)419..457(+)
Misc Feature(3)569..583(+)
Misc Feature(4)2087..2281(+)
Translation

Target ORF information:

RefSeq Version XM_011517045
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens nibrin (NBN), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011517045

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGCAGAATG GCTTTTCCCG AACTTTGAAG TCGGGGGATG GTATTACTTT TGGAGTGTTT 
GGAAGTAAAT TCAGAATAGA GTATGAGCCT TTGGTTGCAT GCTCTTCTTG TTTAGATGTC
TCTGGGAAAA CTGCTTTAAA TCAAGCTATA TTGCAACTTG GAGGATTTAC TGTAAACAAT
TGGACAGAAG AATGCACTCA CCTTGTCATG GTATCAGTGA AAGTTACCAT TAAAACAATA
TGTGCACTCA TTTGTGGACG TCCAATTGTA AAGCCAGAAT ATTTTACTGA ATTCCTGAAA
GCAGTTGAGT CCAAGAAGCA GCCTCCACAA ATTGAAAGTT TTTACCCACC TCTTGATGAA
CCATCTATTG GAAGTAAAAA TGTTGATCTG TCAGGACGGC AGGAAAGAAA ACAAATCTTC
AAAGGGAAAA CATTTATATT TTTGAATGCC AAACAGCATA AGAAATTGAG TTCCGCAGTT
GTCTTTGGAG GTGGGGAAGC TAGGTTGATA ACAGAAGAGA ATGAAGAAGA ACATAATTTC
TTTTTGGCTC CGGGAACGTG TGTTGTTGAT ACAGGAATAA CAAACTCACA GACCTTAATT
CCTGACTGTC AGAAGAAATG GATTCAGTCA ATAATGGATA TGCTCCAAAG GCAAGGTCTT
AGACCTATTC CTGAAGCAGA AATTGGATTG GCGGTGATTT TCATGACTAC AAAGAATTAC
TGTGATCCTC AGGGCCATCC CAGTACAGGA TTAAAGACAA CAACTCCAGG ACCAAGCCTT
TCACAAGGCG TGTCAGTTGA TGAAAAACTA ATGCCAAGCG CCCCAGTGAA CACTACAACA
TACGTAGCTG ACACAGAATC AGAGCAAGCA GATACATGGG ATTTGAGTGA AAGGCCAAAA
GAAATCAAAG TCTCCAAAAT GGAACAAAAA TTCAGAATGC TTTCACAAGA TGCACCCACT
GTAAAGGAGT CCTGCAAAAC AAGCTCTAAT AATAATAGTA TGGTATCAAA TACTTTGGCT
AAGATGAGAA TCCCAAACTA TCAGCTTTCA CCAACTAAAT TGCCAAGTAT AAATAAAAGT
AAAGATAGGG CTTCTCAGCA GCAGCAGACC AACTCCATCA GAAACTACTT TCAGCCGTCT
ACCAAAAAAA GGGAAAGGGA TGAAGAAAAT CAAGAAATGT CTTCATGCAA ATCAGCAAGA
ATAGAAACGT CTTGTTCTCT TTTAGAACAA ACACAACCTG CTACACCCTC ATTGTGGAAA
AATAAGGAGC AGCATCTATC TGAGAATGAG CCTGTGGACA CAAACTCAGA CAATAACTTA
TTTACAGATA CAGATTTAAA ATCTATTGTG AAAAATTCTG CCAGTAAATC TCATGCTGCA
GAAAAGCTAA GATCAAATAA AAAAAGGGAA ATGGATGATG TGGCCATAGA AGATGAAGTA
TTGGAACAGT TATTCAAGGA CACAAAACCA GAGTTAGAAA TTGATGTGAA AGTTCAAAAA
CAGGAGGAAG ATGTCAATGT TAGAAAAAGG CCAAGGATGG ATATAGAAAC AAATGACACT
TTCAGTGATG AAGCAGTACC AGAAAGTAGC AAAATATCTC AAGAAAATGA AATTGGGAAG
AAACGTGAAC TCAAGGAAGA CTCACTATGG TCAGCTAAAG AAATATCTAA CAATGACAAA
CTTCAGGATG ATAGTGAGAT GCTTCCAAAA AAGCTGTTAT TGACTGAATT TAGATCACTG
GTGATTAAAA ACTCTACTTC CAGAAATCCA TCTGGCATAA ATGATGATTA TGGTCAACTA
AAAAATTTCA AGAAATTCAA AAAGGTCACA TATCCTGGAG CAGGAAAACT TCCACACATC
ATTGGAGGAT CAGATCTAAT AGCTCATCAT GCTCGAAAGA ATACAGAACT AGAAGAGTGG
CTAAGGCAGG AAATGGAGGT ACAAAATCAA CATGCAAAAG AAGAGTCTCT TGCTGATGAT
CTTTTTAGAT ACAATCCTTA TTTAAAAAGG AGAAGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu59212
Clone ID Related Accession (Same CDS sequence) XM_011517046
Accession Version XM_011517046.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1410bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product nibrin isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008046.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGTGGAAAC TGCTGCCCGC CGCGGGCCCG GCAGGAGGAG AACCATACAG ACTTTTGACT 
GGCGTTGAGT ACGTTGTTGG AAGGAAAAAC TGTGCCATTC TGATTGAAAA TGATCAGTCG
ATCAGCCGAA ATCATGCTGT GTTAACTGCT AACTTTTCTG TAACCAACCT GAGTCAAACA
GATGAAATCC CTGTATTGAC ATTAAAAGAT AATTCTAAGT ATGGTACCTT TGTTAATGAG
GAAAAAATGC AGAATGGCTT TTCCCGAACT TTGAAGTCGG GGGATGGTAT TACTTTTGGA
GTGTTTGGAA GTAAATTCAG AATAGAGTAT GAGCCTTTGG TTGCATGCTC TTCTTGTTTA
GATGTCTCTG GGAAAACTGC TTTAAATCAA GCTATATTGC AACTTGGAGG ATTTACTGTA
AACAATTGGA CAGAAGAATG CACTCACCTT GTCATGGTAT CAGTGAAAGT TACCATTAAA
ACAATATGTG CACTCATTTG TGGACGTCCA ATTGTAAAGC CAGAATATTT TACTGAATTC
CTGAAAGCAG TTGAGTCCAA GAAGCAGCCT CCACAAATTG AAAGTTTTTA CCCACCTCTT
GATGAACCAT CTATTGGAAG TAAAAATGTT GATCTGTCAG GACGGCAGGA AAGAAAACAA
ATCTTCAAAG GGAAAACATT TATATTTTTG AATGCCAAAC AGCATAAGAA ATTGAGTTCC
GCAGTTGTCT TTGGAGGTGG GGAAGCTAGG TTGATAACAG AAGAGAATGA AGAAGAACAT
AATTTCTTTT TGGCTCCGGG AACGTGTGTT GTTGATACAG GAATAACAAA CTCACAGACC
TTAATTCCTG ACTGTCAGAA GAAATGGATT CAGTCAATAA TGGATATGCT CCAAAGGCAA
GGTCTTAGAC CTATTCCTGA AGCAGAAATT GGATTGGCGG TGATTTTCAT GACTACAAAG
AATTACTGTG ATCCTCAGGG CCATCCCAGT ACAGGATTAA AGACAACAAC TCCAGGACCA
AGCCTTTCAC AAGGCGTGTC AGTTGATGAA AAACTAATGC CAAGCGCCCC AGTGAACACT
ACAACATACG TAGCTGACAC AGAATCAGAG CAAGCAGATA CATGGGATTT GAGTGAAAGG
CCAAAAGAAA TCAAAGTCTC CAAAATGGAA CAAAAATTCA GAATGCTTTC ACAAGATGCA
CCCACTGTAA AGGAGTCCTG CAAAACAAGC TCTAATAATA ATAGTATGGT ATCAAATACT
TTGGCTAAGA TGAGAATCCC AAACTATCAG CTTTCACCAA CTAAATTGCC AAGTATAAAT
AAAAGTAAAG ATAGGGCTTC TCAGCAGCAG CAGACCAACT CCATCAGAAA CTACTTTCAG
CCGTCTACCA AAAAAAAGGG AAAGGGATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011515348.1
CDS138..1547
Misc Feature(1)138..464(+)
Misc Feature(2)219..362(+)
Misc Feature(3)477..683(+)
Misc Feature(4)513..551(+)
Misc Feature(5)663..677(+)
Translation

Target ORF information:

RefSeq Version XM_011517046
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens nibrin (NBN), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011517046

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGTGGAAAC TGCTGCCCGC CGCGGGCCCG GCAGGAGGAG AACCATACAG ACTTTTGACT 
GGCGTTGAGT ACGTTGTTGG AAGGAAAAAC TGTGCCATTC TGATTGAAAA TGATCAGTCG
ATCAGCCGAA ATCATGCTGT GTTAACTGCT AACTTTTCTG TAACCAACCT GAGTCAAACA
GATGAAATCC CTGTATTGAC ATTAAAAGAT AATTCTAAGT ATGGTACCTT TGTTAATGAG
GAAAAAATGC AGAATGGCTT TTCCCGAACT TTGAAGTCGG GGGATGGTAT TACTTTTGGA
GTGTTTGGAA GTAAATTCAG AATAGAGTAT GAGCCTTTGG TTGCATGCTC TTCTTGTTTA
GATGTCTCTG GGAAAACTGC TTTAAATCAA GCTATATTGC AACTTGGAGG ATTTACTGTA
AACAATTGGA CAGAAGAATG CACTCACCTT GTCATGGTAT CAGTGAAAGT TACCATTAAA
ACAATATGTG CACTCATTTG TGGACGTCCA ATTGTAAAGC CAGAATATTT TACTGAATTC
CTGAAAGCAG TTGAGTCCAA GAAGCAGCCT CCACAAATTG AAAGTTTTTA CCCACCTCTT
GATGAACCAT CTATTGGAAG TAAAAATGTT GATCTGTCAG GACGGCAGGA AAGAAAACAA
ATCTTCAAAG GGAAAACATT TATATTTTTG AATGCCAAAC AGCATAAGAA ATTGAGTTCC
GCAGTTGTCT TTGGAGGTGG GGAAGCTAGG TTGATAACAG AAGAGAATGA AGAAGAACAT
AATTTCTTTT TGGCTCCGGG AACGTGTGTT GTTGATACAG GAATAACAAA CTCACAGACC
TTAATTCCTG ACTGTCAGAA GAAATGGATT CAGTCAATAA TGGATATGCT CCAAAGGCAA
GGTCTTAGAC CTATTCCTGA AGCAGAAATT GGATTGGCGG TGATTTTCAT GACTACAAAG
AATTACTGTG ATCCTCAGGG CCATCCCAGT ACAGGATTAA AGACAACAAC TCCAGGACCA
AGCCTTTCAC AAGGCGTGTC AGTTGATGAA AAACTAATGC CAAGCGCCCC AGTGAACACT
ACAACATACG TAGCTGACAC AGAATCAGAG CAAGCAGATA CATGGGATTT GAGTGAAAGG
CCAAAAGAAA TCAAAGTCTC CAAAATGGAA CAAAAATTCA GAATGCTTTC ACAAGATGCA
CCCACTGTAA AGGAGTCCTG CAAAACAAGC TCTAATAATA ATAGTATGGT ATCAAATACT
TTGGCTAAGA TGAGAATCCC AAACTATCAG CTTTCACCAA CTAAATTGCC AAGTATAAAT
AAAAGTAAAG ATAGGGCTTC TCAGCAGCAG CAGACCAACT CCATCAGAAA CTACTTTCAG
CCGTCTACCA AAAAAAAGGG AAAGGGATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25559
Clone ID Related Accession (Same CDS sequence) NM_002485
Accession Version NM_002485.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2265bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product nibrin
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX640816.1, BC071590.1 and BC040519.1. This sequence is a reference standard in the RefSeqGene project. On Jun 9, 2005 this sequence version replaced gi:33356171. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC146797.1, AF051334.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGTGGAAAC TGCTGCCCGC CGCGGGCCCG GCAGGAGGAG AACCATACAG ACTTTTGACT 
GGCGTTGAGT ACGTTGTTGG AAGGAAAAAC TGTGCCATTC TGATTGAAAA TGATCAGTCG
ATCAGCCGAA ATCATGCTGT GTTAACTGCT AACTTTTCTG TAACCAACCT GAGTCAAACA
GATGAAATCC CTGTATTGAC ATTAAAAGAT AATTCTAAGT ATGGTACCTT TGTTAATGAG
GAAAAAATGC AGAATGGCTT TTCCCGAACT TTGAAGTCGG GGGATGGTAT TACTTTTGGA
GTGTTTGGAA GTAAATTCAG AATAGAGTAT GAGCCTTTGG TTGCATGCTC TTCTTGTTTA
GATGTCTCTG GGAAAACTGC TTTAAATCAA GCTATATTGC AACTTGGAGG ATTTACTGTA
AACAATTGGA CAGAAGAATG CACTCACCTT GTCATGGTAT CAGTGAAAGT TACCATTAAA
ACAATATGTG CACTCATTTG TGGACGTCCA ATTGTAAAGC CAGAATATTT TACTGAATTC
CTGAAAGCAG TTGAGTCCAA GAAGCAGCCT CCACAAATTG AAAGTTTTTA CCCACCTCTT
GATGAACCAT CTATTGGAAG TAAAAATGTT GATCTGTCAG GACGGCAGGA AAGAAAACAA
ATCTTCAAAG GGAAAACATT TATATTTTTG AATGCCAAAC AGCATAAGAA ATTGAGTTCC
GCAGTTGTCT TTGGAGGTGG GGAAGCTAGG TTGATAACAG AAGAGAATGA AGAAGAACAT
AATTTCTTTT TGGCTCCGGG AACGTGTGTT GTTGATACAG GAATAACAAA CTCACAGACC
TTAATTCCTG ACTGTCAGAA GAAATGGATT CAGTCAATAA TGGATATGCT CCAAAGGCAA
GGTCTTAGAC CTATTCCTGA AGCAGAAATT GGATTGGCGG TGATTTTCAT GACTACAAAG
AATTACTGTG ATCCTCAGGG CCATCCCAGT ACAGGATTAA AGACAACAAC TCCAGGACCA
AGCCTTTCAC AAGGCGTGTC AGTTGATGAA AAACTAATGC CAAGCGCCCC AGTGAACACT
ACAACATACG TAGCTGACAC AGAATCAGAG CAAGCAGATA CATGGGATTT GAGTGAAAGG
CCAAAAGAAA TCAAAGTCTC CAAAATGGAA CAAAAATTCA GAATGCTTTC ACAAGATGCA
CCCACTGTAA AGGAGTCCTG CAAAACAAGC TCTAATAATA ATAGTATGGT ATCAAATACT
TTGGCTAAGA TGAGAATCCC AAACTATCAG CTTTCACCAA CTAAATTGCC AAGTATAAAT
AAAAGTAAAG ATAGGGCTTC TCAGCAGCAG CAGACCAACT CCATCAGAAA CTACTTTCAG
CCGTCTACCA AAAAAAGGGA AAGGGATGAA GAAAATCAAG AAATGTCTTC ATGCAAATCA
GCAAGAATAG AAACGTCTTG TTCTCTTTTA GAACAAACAC AACCTGCTAC ACCCTCATTG
TGGAAAAATA AGGAGCAGCA TCTATCTGAG AATGAGCCTG TGGACACAAA CTCAGACAAT
AACTTATTTA CAGATACAGA TTTAAAATCT ATTGTGAAAA ATTCTGCCAG TAAATCTCAT
GCTGCAGAAA AGCTAAGATC AAATAAAAAA AGGGAAATGG ATGATGTGGC CATAGAAGAT
GAAGTATTGG AACAGTTATT CAAGGACACA AAACCAGAGT TAGAAATTGA TGTGAAAGTT
CAAAAACAGG AGGAAGATGT CAATGTTAGA AAAAGGCCAA GGATGGATAT AGAAACAAAT
GACACTTTCA GTGATGAAGC AGTACCAGAA AGTAGCAAAA TATCTCAAGA AAATGAAATT
GGGAAGAAAC GTGAACTCAA GGAAGACTCA CTATGGTCAG CTAAAGAAAT ATCTAACAAT
GACAAACTTC AGGATGATAG TGAGATGCTT CCAAAAAAGC TGTTATTGAC TGAATTTAGA
TCACTGGTGA TTAAAAACTC TACTTCCAGA AATCCATCTG GCATAAATGA TGATTATGGT
CAACTAAAAA ATTTCAAGAA ATTCAAAAAG GTCACATATC CTGGAGCAGG AAAACTTCCA
CACATCATTG GAGGATCAGA TCTAATAGCT CATCATGCTC GAAAGAATAC AGAACTAGAA
GAGTGGCTAA GGCAGGAAAT GGAGGTACAA AATCAACATG CAAAAGAAGA GTCTCTTGCT
GATGATCTTT TTAGATACAA TCCTTATTTA AAAAGGAGAA GATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002476.2
CDS111..2375
Misc Feature(1)96..98(+)
Misc Feature(2)111..437(+)
Misc Feature(3)192..335(+)
Misc Feature(4)441..1094(+)
Misc Feature(5)450..656(+)
Misc Feature(6)486..524(+)
Misc Feature(7)636..650(+)
Misc Feature(8)771..1316(+)
Misc Feature(9)942..944(+)
Misc Feature(10)942..944(+)
Misc Feature(11)1137..1139(+)
Misc Feature(12)1137..1139(+)
Misc Feature(13)1299..1301(+)
Misc Feature(14)1299..1301(+)
Misc Feature(15)1314..1316(+)
Misc Feature(16)1395..1397(+)
Misc Feature(17)1404..1406(+)
Misc Feature(18)1404..1406(+)
Misc Feature(19)1491..1511(+)
Misc Feature(20)1953..1955(+)
Misc Feature(21)2154..2348(+)
Misc Feature(22)2316..2339(+)
Exon (1)1..147
Gene:NBN
Gene Synonym:
Exon (2)148..281
Gene:NBN
Gene Synonym:
Exon (3)282..430
Gene:NBN
Gene Synonym:
Exon (4)431..590
Gene:NBN
Gene Synonym:
Exon (5)591..694
Gene:NBN
Gene Synonym:
Exon (6)695..812
Gene:NBN
Gene Synonym:
Exon (7)813..1006
Gene:NBN
Gene Synonym:
Exon (8)1007..1104
Gene:NBN
Gene Synonym:
Exon (9)1105..1234
Gene:NBN
Gene Synonym:
Exon (10)1235..1507
Gene:NBN
Gene Synonym:
Exon (11)1508..1955
Gene:NBN
Gene Synonym:
Exon (12)1956..2024
Gene:NBN
Gene Synonym:
Exon (13)2025..2180
Gene:NBN
Gene Synonym:
Exon (14)2181..2294
Gene:NBN
Gene Synonym:
Exon (15)2295..2344
Gene:NBN
Gene Synonym:
Exon (16)2345..4621
Gene:NBN
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_002485
Organism Homo sapiens (human)
Definition Homo sapiens nibrin (NBN), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002485

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGTGGAAAC TGCTGCCCGC CGCGGGCCCG GCAGGAGGAG AACCATACAG ACTTTTGACT 
GGCGTTGAGT ACGTTGTTGG AAGGAAAAAC TGTGCCATTC TGATTGAAAA TGATCAGTCG
ATCAGCCGAA ATCATGCTGT GTTAACTGCT AACTTTTCTG TAACCAACCT GAGTCAAACA
GATGAAATCC CTGTATTGAC ATTAAAAGAT AATTCTAAGT ATGGTACCTT TGTTAATGAG
GAAAAAATGC AGAATGGCTT TTCCCGAACT TTGAAGTCGG GGGATGGTAT TACTTTTGGA
GTGTTTGGAA GTAAATTCAG AATAGAGTAT GAGCCTTTGG TTGCATGCTC TTCTTGTTTA
GATGTCTCTG GGAAAACTGC TTTAAATCAA GCTATATTGC AACTTGGAGG ATTTACTGTA
AACAATTGGA CAGAAGAATG CACTCACCTT GTCATGGTAT CAGTGAAAGT TACCATTAAA
ACAATATGTG CACTCATTTG TGGACGTCCA ATTGTAAAGC CAGAATATTT TACTGAATTC
CTGAAAGCAG TTGAGTCCAA GAAGCAGCCT CCACAAATTG AAAGTTTTTA CCCACCTCTT
GATGAACCAT CTATTGGAAG TAAAAATGTT GATCTGTCAG GACGGCAGGA AAGAAAACAA
ATCTTCAAAG GGAAAACATT TATATTTTTG AATGCCAAAC AGCATAAGAA ATTGAGTTCC
GCAGTTGTCT TTGGAGGTGG GGAAGCTAGG TTGATAACAG AAGAGAATGA AGAAGAACAT
AATTTCTTTT TGGCTCCGGG AACGTGTGTT GTTGATACAG GAATAACAAA CTCACAGACC
TTAATTCCTG ACTGTCAGAA GAAATGGATT CAGTCAATAA TGGATATGCT CCAAAGGCAA
GGTCTTAGAC CTATTCCTGA AGCAGAAATT GGATTGGCGG TGATTTTCAT GACTACAAAG
AATTACTGTG ATCCTCAGGG CCATCCCAGT ACAGGATTAA AGACAACAAC TCCAGGACCA
AGCCTTTCAC AAGGCGTGTC AGTTGATGAA AAACTAATGC CAAGCGCCCC AGTGAACACT
ACAACATACG TAGCTGACAC AGAATCAGAG CAAGCAGATA CATGGGATTT GAGTGAAAGG
CCAAAAGAAA TCAAAGTCTC CAAAATGGAA CAAAAATTCA GAATGCTTTC ACAAGATGCA
CCCACTGTAA AGGAGTCCTG CAAAACAAGC TCTAATAATA ATAGTATGGT ATCAAATACT
TTGGCTAAGA TGAGAATCCC AAACTATCAG CTTTCACCAA CTAAATTGCC AAGTATAAAT
AAAAGTAAAG ATAGGGCTTC TCAGCAGCAG CAGACCAACT CCATCAGAAA CTACTTTCAG
CCGTCTACCA AAAAAAGGGA AAGGGATGAA GAAAATCAAG AAATGTCTTC ATGCAAATCA
GCAAGAATAG AAACGTCTTG TTCTCTTTTA GAACAAACAC AACCTGCTAC ACCCTCATTG
TGGAAAAATA AGGAGCAGCA TCTATCTGAG AATGAGCCTG TGGACACAAA CTCAGACAAT
AACTTATTTA CAGATACAGA TTTAAAATCT ATTGTGAAAA ATTCTGCCAG TAAATCTCAT
GCTGCAGAAA AGCTAAGATC AAATAAAAAA AGGGAAATGG ATGATGTGGC CATAGAAGAT
GAAGTATTGG AACAGTTATT CAAGGACACA AAACCAGAGT TAGAAATTGA TGTGAAAGTT
CAAAAACAGG AGGAAGATGT CAATGTTAGA AAAAGGCCAA GGATGGATAT AGAAACAAAT
GACACTTTCA GTGATGAAGC AGTACCAGAA AGTAGCAAAA TATCTCAAGA AAATGAAATT
GGGAAGAAAC GTGAACTCAA GGAAGACTCA CTATGGTCAG CTAAAGAAAT ATCTAACAAT
GACAAACTTC AGGATGATAG TGAGATGCTT CCAAAAAAGC TGTTATTGAC TGAATTTAGA
TCACTGGTGA TTAAAAACTC TACTTCCAGA AATCCATCTG GCATAAATGA TGATTATGGT
CAACTAAAAA ATTTCAAGAA ATTCAAAAAG GTCACATATC CTGGAGCAGG AAAACTTCCA
CACATCATTG GAGGATCAGA TCTAATAGCT CATCATGCTC GAAAGAATAC AGAACTAGAA
GAGTGGCTAA GGCAGGAAAT GGAGGTACAA AATCAACATG CAAAAGAAGA GTCTCTTGCT
GATGATCTTT TTAGATACAA TCCTTATTTA AAAAGGAGAA GATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu42449
Clone ID Related Accession (Same CDS sequence) NM_001024688 , XM_011517045
Accession Version NM_001024688.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2019bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 13-APR-2015
Organism Homo sapiens (human)
Product nibrin isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA634817.1, BC040519.1, BC136802.1 and BX640816.1. On or before Apr 2, 2015 this sequence version replaced gi:767953015, gi:67189944. Transcript Variant: This variant (2) has an additional exon in the 5' region, as compared to variant 1. This results in translation initiation from a downstream AUG codon and an isoform (2) with a shorter N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC040519.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGCAGAATG GCTTTTCCCG AACTTTGAAG TCGGGGGATG GTATTACTTT TGGAGTGTTT 
GGAAGTAAAT TCAGAATAGA GTATGAGCCT TTGGTTGCAT GCTCTTCTTG TTTAGATGTC
TCTGGGAAAA CTGCTTTAAA TCAAGCTATA TTGCAACTTG GAGGATTTAC TGTAAACAAT
TGGACAGAAG AATGCACTCA CCTTGTCATG GTATCAGTGA AAGTTACCAT TAAAACAATA
TGTGCACTCA TTTGTGGACG TCCAATTGTA AAGCCAGAAT ATTTTACTGA ATTCCTGAAA
GCAGTTGAGT CCAAGAAGCA GCCTCCACAA ATTGAAAGTT TTTACCCACC TCTTGATGAA
CCATCTATTG GAAGTAAAAA TGTTGATCTG TCAGGACGGC AGGAAAGAAA ACAAATCTTC
AAAGGGAAAA CATTTATATT TTTGAATGCC AAACAGCATA AGAAATTGAG TTCCGCAGTT
GTCTTTGGAG GTGGGGAAGC TAGGTTGATA ACAGAAGAGA ATGAAGAAGA ACATAATTTC
TTTTTGGCTC CGGGAACGTG TGTTGTTGAT ACAGGAATAA CAAACTCACA GACCTTAATT
CCTGACTGTC AGAAGAAATG GATTCAGTCA ATAATGGATA TGCTCCAAAG GCAAGGTCTT
AGACCTATTC CTGAAGCAGA AATTGGATTG GCGGTGATTT TCATGACTAC AAAGAATTAC
TGTGATCCTC AGGGCCATCC CAGTACAGGA TTAAAGACAA CAACTCCAGG ACCAAGCCTT
TCACAAGGCG TGTCAGTTGA TGAAAAACTA ATGCCAAGCG CCCCAGTGAA CACTACAACA
TACGTAGCTG ACACAGAATC AGAGCAAGCA GATACATGGG ATTTGAGTGA AAGGCCAAAA
GAAATCAAAG TCTCCAAAAT GGAACAAAAA TTCAGAATGC TTTCACAAGA TGCACCCACT
GTAAAGGAGT CCTGCAAAAC AAGCTCTAAT AATAATAGTA TGGTATCAAA TACTTTGGCT
AAGATGAGAA TCCCAAACTA TCAGCTTTCA CCAACTAAAT TGCCAAGTAT AAATAAAAGT
AAAGATAGGG CTTCTCAGCA GCAGCAGACC AACTCCATCA GAAACTACTT TCAGCCGTCT
ACCAAAAAAA GGGAAAGGGA TGAAGAAAAT CAAGAAATGT CTTCATGCAA ATCAGCAAGA
ATAGAAACGT CTTGTTCTCT TTTAGAACAA ACACAACCTG CTACACCCTC ATTGTGGAAA
AATAAGGAGC AGCATCTATC TGAGAATGAG CCTGTGGACA CAAACTCAGA CAATAACTTA
TTTACAGATA CAGATTTAAA ATCTATTGTG AAAAATTCTG CCAGTAAATC TCATGCTGCA
GAAAAGCTAA GATCAAATAA AAAAAGGGAA ATGGATGATG TGGCCATAGA AGATGAAGTA
TTGGAACAGT TATTCAAGGA CACAAAACCA GAGTTAGAAA TTGATGTGAA AGTTCAAAAA
CAGGAGGAAG ATGTCAATGT TAGAAAAAGG CCAAGGATGG ATATAGAAAC AAATGACACT
TTCAGTGATG AAGCAGTACC AGAAAGTAGC AAAATATCTC AAGAAAATGA AATTGGGAAG
AAACGTGAAC TCAAGGAAGA CTCACTATGG TCAGCTAAAG AAATATCTAA CAATGACAAA
CTTCAGGATG ATAGTGAGAT GCTTCCAAAA AAGCTGTTAT TGACTGAATT TAGATCACTG
GTGATTAAAA ACTCTACTTC CAGAAATCCA TCTGGCATAA ATGATGATTA TGGTCAACTA
AAAAATTTCA AGAAATTCAA AAAGGTCACA TATCCTGGAG CAGGAAAACT TCCACACATC
ATTGGAGGAT CAGATCTAAT AGCTCATCAT GCTCGAAAGA ATACAGAACT AGAAGAGTGG
CTAAGGCAGG AAATGGAGGT ACAAAATCAA CATGCAAAAG AAGAGTCTCT TGCTGATGAT
CTTTTTAGAT ACAATCCTTA TTTAAAAAGG AGAAGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001019859.1
CDS460..2478
Misc Feature(1)313..315(+)
Misc Feature(2)553..759(+)
Misc Feature(3)589..627(+)
Misc Feature(4)739..753(+)
Misc Feature(5)1045..1047(+)
Misc Feature(6)1240..1242(+)
Misc Feature(7)1402..1404(+)
Misc Feature(8)1498..1500(+)
Misc Feature(9)1507..1509(+)
Misc Feature(10)2257..2451(+)
Exon (1)1..200
Gene:NBN
Gene Synonym:
Exon (2)201..334
Gene:NBN
Gene Synonym:
Exon (3)335..384
Gene:NBN
Gene Synonym:
Exon (4)385..533
Gene:NBN
Gene Synonym:
Exon (5)534..693
Gene:NBN
Gene Synonym:
Exon (6)694..797
Gene:NBN
Gene Synonym:
Exon (7)798..915
Gene:NBN
Gene Synonym:
Exon (8)916..1109
Gene:NBN
Gene Synonym:
Exon (9)1110..1207
Gene:NBN
Gene Synonym:
Exon (10)1208..1337
Gene:NBN
Gene Synonym:
Exon (11)1338..1610
Gene:NBN
Gene Synonym:
Exon (12)1611..2058
Gene:NBN
Gene Synonym:
Exon (13)2059..2127
Gene:NBN
Gene Synonym:
Exon (14)2128..2283
Gene:NBN
Gene Synonym:
Exon (15)2284..2397
Gene:NBN
Gene Synonym:
Exon (16)2398..2447
Gene:NBN
Gene Synonym:
Exon (17)2448..4724
Gene:NBN
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001024688
Organism Homo sapiens (human)
Definition Homo sapiens nibrin (NBN), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001024688

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGCAGAATG GCTTTTCCCG AACTTTGAAG TCGGGGGATG GTATTACTTT TGGAGTGTTT 
GGAAGTAAAT TCAGAATAGA GTATGAGCCT TTGGTTGCAT GCTCTTCTTG TTTAGATGTC
TCTGGGAAAA CTGCTTTAAA TCAAGCTATA TTGCAACTTG GAGGATTTAC TGTAAACAAT
TGGACAGAAG AATGCACTCA CCTTGTCATG GTATCAGTGA AAGTTACCAT TAAAACAATA
TGTGCACTCA TTTGTGGACG TCCAATTGTA AAGCCAGAAT ATTTTACTGA ATTCCTGAAA
GCAGTTGAGT CCAAGAAGCA GCCTCCACAA ATTGAAAGTT TTTACCCACC TCTTGATGAA
CCATCTATTG GAAGTAAAAA TGTTGATCTG TCAGGACGGC AGGAAAGAAA ACAAATCTTC
AAAGGGAAAA CATTTATATT TTTGAATGCC AAACAGCATA AGAAATTGAG TTCCGCAGTT
GTCTTTGGAG GTGGGGAAGC TAGGTTGATA ACAGAAGAGA ATGAAGAAGA ACATAATTTC
TTTTTGGCTC CGGGAACGTG TGTTGTTGAT ACAGGAATAA CAAACTCACA GACCTTAATT
CCTGACTGTC AGAAGAAATG GATTCAGTCA ATAATGGATA TGCTCCAAAG GCAAGGTCTT
AGACCTATTC CTGAAGCAGA AATTGGATTG GCGGTGATTT TCATGACTAC AAAGAATTAC
TGTGATCCTC AGGGCCATCC CAGTACAGGA TTAAAGACAA CAACTCCAGG ACCAAGCCTT
TCACAAGGCG TGTCAGTTGA TGAAAAACTA ATGCCAAGCG CCCCAGTGAA CACTACAACA
TACGTAGCTG ACACAGAATC AGAGCAAGCA GATACATGGG ATTTGAGTGA AAGGCCAAAA
GAAATCAAAG TCTCCAAAAT GGAACAAAAA TTCAGAATGC TTTCACAAGA TGCACCCACT
GTAAAGGAGT CCTGCAAAAC AAGCTCTAAT AATAATAGTA TGGTATCAAA TACTTTGGCT
AAGATGAGAA TCCCAAACTA TCAGCTTTCA CCAACTAAAT TGCCAAGTAT AAATAAAAGT
AAAGATAGGG CTTCTCAGCA GCAGCAGACC AACTCCATCA GAAACTACTT TCAGCCGTCT
ACCAAAAAAA GGGAAAGGGA TGAAGAAAAT CAAGAAATGT CTTCATGCAA ATCAGCAAGA
ATAGAAACGT CTTGTTCTCT TTTAGAACAA ACACAACCTG CTACACCCTC ATTGTGGAAA
AATAAGGAGC AGCATCTATC TGAGAATGAG CCTGTGGACA CAAACTCAGA CAATAACTTA
TTTACAGATA CAGATTTAAA ATCTATTGTG AAAAATTCTG CCAGTAAATC TCATGCTGCA
GAAAAGCTAA GATCAAATAA AAAAAGGGAA ATGGATGATG TGGCCATAGA AGATGAAGTA
TTGGAACAGT TATTCAAGGA CACAAAACCA GAGTTAGAAA TTGATGTGAA AGTTCAAAAA
CAGGAGGAAG ATGTCAATGT TAGAAAAAGG CCAAGGATGG ATATAGAAAC AAATGACACT
TTCAGTGATG AAGCAGTACC AGAAAGTAGC AAAATATCTC AAGAAAATGA AATTGGGAAG
AAACGTGAAC TCAAGGAAGA CTCACTATGG TCAGCTAAAG AAATATCTAA CAATGACAAA
CTTCAGGATG ATAGTGAGAT GCTTCCAAAA AAGCTGTTAT TGACTGAATT TAGATCACTG
GTGATTAAAA ACTCTACTTC CAGAAATCCA TCTGGCATAA ATGATGATTA TGGTCAACTA
AAAAATTTCA AGAAATTCAA AAAGGTCACA TATCCTGGAG CAGGAAAACT TCCACACATC
ATTGGAGGAT CAGATCTAAT AGCTCATCAT GCTCGAAAGA ATACAGAACT AGAAGAGTGG
CTAAGGCAGG AAATGGAGGT ACAAAATCAA CATGCAAAAG AAGAGTCTCT TGCTGATGAT
CTTTTTAGAT ACAATCCTTA TTTAAAAAGG AGAAGATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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