Email to GenScript

ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide [Homo sapiens (human)]

Gene Symbol ATP1A3
Entrez Gene ID 478
Full Name ATPase, Na+/K+ transporting, alpha 3 polypeptide
Synonyms AHC2, CAPOS, DYT12, RDP
General protein information
Preferred Names
sodium/potassium-transporting ATPase subunit alpha-3
Names
sodium/potassium-transporting ATPase subunit alpha-3
Na+/K+ ATPase 3
sodium pump subunit alpha-3
Na(+)/K(+) ATPase alpha-3 subunit
Na(+)/K(+) ATPase alpha(III) subunit
sodium-potassium-ATPase, alpha 3 polypeptide
sodium-potassium ATPase catalytic subunit alpha-3
sodium/potassium-transporting ATPase alpha-3 chain
NP_001243142.1
NP_001243143.1
NP_689509.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q13.31

Summary The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]. lac of sum
Disorder MIM:

182350

Disorder Html: Dystonia-12, 128235 (3)





The following ATP1A3 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ATP1A3 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu56402 XM_011526991 PREDICTED: Homo sapiens ATPase, Na+/K+ transporting, alpha 3 polypeptide (ATP1A3), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 Quote Price
OHu26791 NM_152296 Homo sapiens ATPase, Na+/K+ transporting, alpha 3 polypeptide (ATP1A3), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$384.3
$549
OHu26608 NM_001256213 Homo sapiens ATPase, Na+/K+ transporting, alpha 3 polypeptide (ATP1A3), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price
OHu27445 NM_001256214 Homo sapiens ATPase, Na+/K+ transporting, alpha 3 polypeptide (ATP1A3), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 Quote Price

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu56402
Accession Version XM_011526991.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2952bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product sodium/potassium-transporting ATPase subunit alpha-3 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011109.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
ATGACAGAGC ACAAGATGTC AGTGGAAGAG GTCTGCCGGA AATACAACAC AGACTGTGTG 
CAGGGTTTGA CCCACAGCAA AGCCCAGGAG ATCCTGGCCC GGGATGGGCC TAACGCACTC
ACGCCACCGC CTACCACCCC AGAGTGGGTC AAGTTTTGCC GGCAGCTCTT CGGGGGCTTC
TCCATCCTGC TGTGGATCGG GGCTATCCTC TGCTTCCTGG CCTACGGTAT CCAGGCGGGC
ACCGAGGACG ACCCCTCTGG TGACAACCTG TACCTGGGCA TCGTGCTGGC GGCCGTGGTG
ATCATCACTG GCTGCTTCTC CTACTACCAG GAGGCCAAGA GCTCCAAGAT CATGGAGTCC
TTCAAGAACA TGGTGCCCCA GCAAGCCCTG GTGATCCGGG AAGGTGAGAA GATGCAGGTG
AACGCTGAGG AGGTGGTGGT CGGGGACCTG GTGGAGATCA AGGGTGGAGA CCGAGTGCCA
GCTGACCTGC GGATCATCTC AGCCCACGGC TGCAAGGTGG ACAACTCCTC CCTGACTGGC
GAATCCGAGC CCCAGACTCG CTCTCCCGAC TGCACTCACG ACAACCCCTT GGAGACTCGG
AACATCACCT TCTTTTCCAC CAACTGTGTG GAAGGCACGG CTCGGGGCGT GGTGGTGGCC
ACGGGCGACC GCACTGTCAT GGGCCGTATC GCCACCCTGG CATCAGGGCT GGAGGTGGGC
AAGACGCCCA TCGCCATCGA GATTGAGCAC TTCATCCAGC TCATCACCGG CGTGGCTGTC
TTCCTGGGTG TCTCCTTCTT CATCCTCTCC CTCATTCTCG GATACACCTG GCTTGAGGCT
GTCATCTTCC TCATCGGCAT CATCGTGGCC AATGTCCCAG AGGGTCTGCT GGCCACTGTC
ACTGTGTGTC TGACGCTGAC CGCCAAGCGC ATGGCCCGGA AGAACTGCCT GGTGAAGAAC
CTGGAGGCTG TAGAAACCCT GGGCTCCACG TCCACCATCT GCTCAGATAA GACAGGGACC
CTCACTCAGA ACCGCATGAC AGTCGCCCAC ATGTGGTTTG ACAACCAGAT CCACGAGGCT
GACACCACTG AGGACCAGTC AGGGACCTCA TTTGACAAGA GTTCGCACAC CTGGGTGGCC
CTGTCTCACA TCGCTGGGCT CTGCAATCGC GCTGTCTTCA AGGGTGGTCA GGACAACATC
CCTGTGCTCA AGAGGGATGT GGCTGGGGAT GCGTCTGAGT CTGCCCTGCT CAAGTGCATC
GAGCTGTCCT CTGGCTCCGT GAAGCTGATG CGTGAACGCA ACAAGAAAGT GGCTGAGATT
CCCTTCAATT CCACCAACAA ATACCAGCTC TCCATCCATG AGACCGAGGA CCCCAACGAC
AACCGATACC TGCTGGTGAT GAAGGGTGCC CCCGAGCGCA TCCTGGACCG CTGCTCCACC
ATCCTGCTAC AGGGCAAGGA GCAGCCTCTG GACGAGGAAA TGAAGGAGGC CTTCCAGAAT
GCCTACCTTG AGCTCGGTGG CCTGGGCGAG CGCGTGCTTG GTTTCTGCCA TTATTACCTG
CCCGAGGAGC AGTTCCCCAA GGGCTTTGCC TTCGACTGTG ATGACGTGAA CTTCACCACG
GACAACCTCT GCTTTGTGGG CCTCATGTCC ATGATCGACC CACCCCGGGC AGCCGTCCCT
GACGCGGTGG GCAAGTGTCG CAGCGCAGGC ATCAAGGTCA TCATGGTCAC CGGCGATCAC
CCCATCACGG CCAAGGCCAT TGCCAAGGGT GTGGGCATCA TCTCTGAGGG CAACGAGACT
GTGGAGGACA TCGCCGCCCG GCTCAACATT CCCGTCAGCC AGGTTAACCC CCGGGATGCC
AAGGCCTGCG TGATCCACGG CACCGACCTC AAGGACTTCA CCTCCGAGCA AATCGACGAG
ATCCTGCAGA ATCACACCGA GATCGTCTTC GCCCGCACAT CCCCCCAGCA GAAGCTCATC
ATTGTGGAGG GCTGTCAGAG ACAGGGTGCA ATTGTGGCTG TGACCGGGGA TGGTGTGAAC
GACTCCCCCG CTCTGAAGAA GGCCGACATT GGGGTGGCCA TGGGCATCGC TGGCTCTGAC
GTCTCCAAGC AGGCAGCTGA CATGATCCTG CTGGACGACA ACTTTGCCTC CATCGTCACA
GGGGTGGAGG AGGGCCGCCT GATCTTCGAC AACCTAAAGA AGTCCATTGC CTACACCCTG
ACCAGCAATA TCCCGGAGAT CACGCCCTTC CTGCTGTTCA TCATGGCCAA CATCCCGCTG
CCCCTGGGCA CCATCACCAT CCTCTGCATC GATCTGGGCA CTGACATGGT CCCTGCCATC
TCACTGGCGT ACGAGGCTGC CGAAAGCGAC ATCATGAAGA GACAGCCCAG GAACCCGCGG
ACGGACAAAT TGGTCAATGA GAGACTCATC AGCATGGCCT ACGGGCAGAT TGGAATGATC
CAGGCTCTCG GTGGCTTCTT CTCTTACTTT GTGATCCTGG CAGAAAATGG CTTCTTGCCC
GGCAACCTGG TGGGCATCCG GCTGAACTGG GATGACCGCA CCGTCAATGA CCTGGAAGAC
AGTTACGGGC AGCAGTGGAC ATACGAGCAG AGGAAGGTGG TGGAGTTCAC CTGCCACACG
GCCTTCTTTG TGAGCATCGT TGTCGTCCAG TGGGCCGATC TGATCATCTG CAAGACCCGG
AGGAACTCGG TCTTCCAGCA GGGCATGAAG AACAAGATCC TGATCTTCGG GCTGTTTGAG
GAGACGGCCC TGGCTGCCTT CCTGTCCTAC TGCCCCGGCA TGGACGTGGC CCTGCGCATG
TACCCTCTCA AGCCCAGCTG GTGGTTCTGT GCCTTCCCCT ACAGTTTCCT CATCTTCGTC
TACGACGAAA TCCGCAAACT CATCCTGCGC AGGAACCCAG GGGGTTGGGT GGAGAAGGAA
ACCTACTACT GA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011525293.1
CDS154..3105
Misc Feature(1)154..3102(+)
Misc Feature(2)154..375(+)
Misc Feature(3)436..1131(+)
Misc Feature(4)1312..1596(+)
Misc Feature(5)1747..1887(+)
Misc Feature(6)1747..1764(+)
Misc Feature(7)1849..2289(+)
Misc Feature(8)1882..1884(+)
Misc Feature(9)2428..3057(+)
Translation
Position Chain Variation Link
195 195 a, g dbSNP:199577046
270 270 a, c, t dbSNP:200616931
473 473 a, c, t dbSNP:542652468
482 482 a, t dbSNP:606231427
642 642 g, t dbSNP:200860753
729 729 a, g, t dbSNP:2217342
804 804 c, g, t dbSNP:767234141
884 884 a, c, t dbSNP:80356532
892 892 a, g dbSNP:80356533
1028 1028 a, t dbSNP:606231428
1039 1039 -, ctg dbSNP:397515578
1042 1042 -, ctg dbSNP:606231429
1061 1061 g, t dbSNP:606231430
1066 1066 a, c dbSNP:606231431
1135 1135 g, t dbSNP:606231432
1172 1172 a, c dbSNP:573535377
1175 1175 c, t dbSNP:606231433
1185 1185 c, t dbSNP:776748534
1207 1207 c, t dbSNP:606231448
1261 1261 a, t dbSNP:760884114
1313 1313 c, t dbSNP:606231449
1386 1386 a, g, t dbSNP:34578730
1582 1582 c, t dbSNP:749776123
1901 1901 c, t dbSNP:80356534
2077 2077 c, t dbSNP:267605506
2114 2114 c, t dbSNP:397515577
2176 2176 -, g dbSNP:371698459
2326 2326 a, g, t dbSNP:557052809
2327 2327 c, g dbSNP:606231434
2330 2330 a, g dbSNP:606231435
2333 2333 c, t dbSNP:606231436
2336 2336 g, t dbSNP:80356535
2375 2375 a, c, t dbSNP:557939077
2379 2379 a, c, g dbSNP:534926223
2381 2381 a, g, t dbSNP:606231437
2382 2382 c, t dbSNP:61733017
2401 2401 c, t dbSNP:80356536
2464 2464 a, g, t dbSNP:80356537
2474 2474 c, t dbSNP:606231438
2478 2478 c, g dbSNP:606231439
2480 2480 a, g, t dbSNP:549006436
2491 2491 a, t dbSNP:606231440
2492 2492 a, g, t dbSNP:536681257
2494 2494 c, t dbSNP:387907282
2506 2506 a, g dbSNP:387907281
2515 2515 a, g dbSNP:587777771
2663 2663 a, g dbSNP:606231442
2755 2755 c, t dbSNP:773848258
2818 2818 -, gtc dbSNP:606231443
2830 2830 a, g, t dbSNP:267606670
2843 2843 a, g, t dbSNP:606231444
2844 2844 c, g, t dbSNP:606231445
2902 2902 a, c, g dbSNP:398122887
2927 2927 a, c dbSNP:606231446
3037 3037 g, t dbSNP:606231447
3103 3103 -, act dbSNP:397515382
3144 3144 c, g dbSNP:919390
3158 3158 a, g dbSNP:776731215
3303 3303 -, ctc dbSNP:587778772
3341 3341 c, t dbSNP:199854166
3364 3364 c, t dbSNP:772022012

Target ORF information:

RefSeq Version XM_011526991
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens ATPase, Na+/K+ transporting, alpha 3 polypeptide (ATP1A3), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011526991

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
ATGACAGAGC ACAAGATGTC AGTGGAAGAG GTCTGCCGGA AATACAACAC AGACTGTGTG 
CAGGGTTTGA CCCACAGCAA AGCCCAGGAG ATCCTGGCCC GGGATGGGCC TAACGCACTC
ACGCCACCGC CTACCACCCC AGAGTGGGTC AAGTTTTGCC GGCAGCTCTT CGGGGGCTTC
TCCATCCTGC TGTGGATCGG GGCTATCCTC TGCTTCCTGG CCTACGGTAT CCAGGCGGGC
ACCGAGGACG ACCCCTCTGG TGACAACCTG TACCTGGGCA TCGTGCTGGC GGCCGTGGTG
ATCATCACTG GCTGCTTCTC CTACTACCAG GAGGCCAAGA GCTCCAAGAT CATGGAGTCC
TTCAAGAACA TGGTGCCCCA GCAAGCCCTG GTGATCCGGG AAGGTGAGAA GATGCAGGTG
AACGCTGAGG AGGTGGTGGT CGGGGACCTG GTGGAGATCA AGGGTGGAGA CCGAGTGCCA
GCTGACCTGC GGATCATCTC AGCCCACGGC TGCAAGGTGG ACAACTCCTC CCTGACTGGC
GAATCCGAGC CCCAGACTCG CTCTCCCGAC TGCACTCACG ACAACCCCTT GGAGACTCGG
AACATCACCT TCTTTTCCAC CAACTGTGTG GAAGGCACGG CTCGGGGCGT GGTGGTGGCC
ACGGGCGACC GCACTGTCAT GGGCCGTATC GCCACCCTGG CATCAGGGCT GGAGGTGGGC
AAGACGCCCA TCGCCATCGA GATTGAGCAC TTCATCCAGC TCATCACCGG CGTGGCTGTC
TTCCTGGGTG TCTCCTTCTT CATCCTCTCC CTCATTCTCG GATACACCTG GCTTGAGGCT
GTCATCTTCC TCATCGGCAT CATCGTGGCC AATGTCCCAG AGGGTCTGCT GGCCACTGTC
ACTGTGTGTC TGACGCTGAC CGCCAAGCGC ATGGCCCGGA AGAACTGCCT GGTGAAGAAC
CTGGAGGCTG TAGAAACCCT GGGCTCCACG TCCACCATCT GCTCAGATAA GACAGGGACC
CTCACTCAGA ACCGCATGAC AGTCGCCCAC ATGTGGTTTG ACAACCAGAT CCACGAGGCT
GACACCACTG AGGACCAGTC AGGGACCTCA TTTGACAAGA GTTCGCACAC CTGGGTGGCC
CTGTCTCACA TCGCTGGGCT CTGCAATCGC GCTGTCTTCA AGGGTGGTCA GGACAACATC
CCTGTGCTCA AGAGGGATGT GGCTGGGGAT GCGTCTGAGT CTGCCCTGCT CAAGTGCATC
GAGCTGTCCT CTGGCTCCGT GAAGCTGATG CGTGAACGCA ACAAGAAAGT GGCTGAGATT
CCCTTCAATT CCACCAACAA ATACCAGCTC TCCATCCATG AGACCGAGGA CCCCAACGAC
AACCGATACC TGCTGGTGAT GAAGGGTGCC CCCGAGCGCA TCCTGGACCG CTGCTCCACC
ATCCTGCTAC AGGGCAAGGA GCAGCCTCTG GACGAGGAAA TGAAGGAGGC CTTCCAGAAT
GCCTACCTTG AGCTCGGTGG CCTGGGCGAG CGCGTGCTTG GTTTCTGCCA TTATTACCTG
CCCGAGGAGC AGTTCCCCAA GGGCTTTGCC TTCGACTGTG ATGACGTGAA CTTCACCACG
GACAACCTCT GCTTTGTGGG CCTCATGTCC ATGATCGACC CACCCCGGGC AGCCGTCCCT
GACGCGGTGG GCAAGTGTCG CAGCGCAGGC ATCAAGGTCA TCATGGTCAC CGGCGATCAC
CCCATCACGG CCAAGGCCAT TGCCAAGGGT GTGGGCATCA TCTCTGAGGG CAACGAGACT
GTGGAGGACA TCGCCGCCCG GCTCAACATT CCCGTCAGCC AGGTTAACCC CCGGGATGCC
AAGGCCTGCG TGATCCACGG CACCGACCTC AAGGACTTCA CCTCCGAGCA AATCGACGAG
ATCCTGCAGA ATCACACCGA GATCGTCTTC GCCCGCACAT CCCCCCAGCA GAAGCTCATC
ATTGTGGAGG GCTGTCAGAG ACAGGGTGCA ATTGTGGCTG TGACCGGGGA TGGTGTGAAC
GACTCCCCCG CTCTGAAGAA GGCCGACATT GGGGTGGCCA TGGGCATCGC TGGCTCTGAC
GTCTCCAAGC AGGCAGCTGA CATGATCCTG CTGGACGACA ACTTTGCCTC CATCGTCACA
GGGGTGGAGG AGGGCCGCCT GATCTTCGAC AACCTAAAGA AGTCCATTGC CTACACCCTG
ACCAGCAATA TCCCGGAGAT CACGCCCTTC CTGCTGTTCA TCATGGCCAA CATCCCGCTG
CCCCTGGGCA CCATCACCAT CCTCTGCATC GATCTGGGCA CTGACATGGT CCCTGCCATC
TCACTGGCGT ACGAGGCTGC CGAAAGCGAC ATCATGAAGA GACAGCCCAG GAACCCGCGG
ACGGACAAAT TGGTCAATGA GAGACTCATC AGCATGGCCT ACGGGCAGAT TGGAATGATC
CAGGCTCTCG GTGGCTTCTT CTCTTACTTT GTGATCCTGG CAGAAAATGG CTTCTTGCCC
GGCAACCTGG TGGGCATCCG GCTGAACTGG GATGACCGCA CCGTCAATGA CCTGGAAGAC
AGTTACGGGC AGCAGTGGAC ATACGAGCAG AGGAAGGTGG TGGAGTTCAC CTGCCACACG
GCCTTCTTTG TGAGCATCGT TGTCGTCCAG TGGGCCGATC TGATCATCTG CAAGACCCGG
AGGAACTCGG TCTTCCAGCA GGGCATGAAG AACAAGATCC TGATCTTCGG GCTGTTTGAG
GAGACGGCCC TGGCTGCCTT CCTGTCCTAC TGCCCCGGCA TGGACGTGGC CCTGCGCATG
TACCCTCTCA AGCCCAGCTG GTGGTTCTGT GCCTTCCCCT ACAGTTTCCT CATCTTCGTC
TACGACGAAA TCCGCAAACT CATCCTGCGC AGGAACCCAG GGGGTTGGGT GGAGAAGGAA
ACCTACTACT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26791
Accession Version NM_152296.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3042bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product sodium/potassium-transporting ATPase subunit alpha-3 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB482528.1, AK223569.1, AK295078.1 and BC009282.2. This sequence is a reference standard in the RefSeqGene project. On Jan 12, 2012 this sequence version replaced gi:49249971. Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]. Transcript Variant: This variant (1) is the predominant transcript and encodes isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC009282.2, AK223569.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962346 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
ATGGGGGACA AGAAAGATGA CAAGGACTCA CCCAAGAAGA ACAAGGGCAA GGAGCGCCGG 
GACCTGGATG ACCTCAAGAA GGAGGTGGCT ATGACAGAGC ACAAGATGTC AGTGGAAGAG
GTCTGCCGGA AATACAACAC AGACTGTGTG CAGGGTTTGA CCCACAGCAA AGCCCAGGAG
ATCCTGGCCC GGGATGGGCC TAACGCACTC ACGCCACCGC CTACCACCCC AGAGTGGGTC
AAGTTTTGCC GGCAGCTCTT CGGGGGCTTC TCCATCCTGC TGTGGATCGG GGCTATCCTC
TGCTTCCTGG CCTACGGTAT CCAGGCGGGC ACCGAGGACG ACCCCTCTGG TGACAACCTG
TACCTGGGCA TCGTGCTGGC GGCCGTGGTG ATCATCACTG GCTGCTTCTC CTACTACCAG
GAGGCCAAGA GCTCCAAGAT CATGGAGTCC TTCAAGAACA TGGTGCCCCA GCAAGCCCTG
GTGATCCGGG AAGGTGAGAA GATGCAGGTG AACGCTGAGG AGGTGGTGGT CGGGGACCTG
GTGGAGATCA AGGGTGGAGA CCGAGTGCCA GCTGACCTGC GGATCATCTC AGCCCACGGC
TGCAAGGTGG ACAACTCCTC CCTGACTGGC GAATCCGAGC CCCAGACTCG CTCTCCCGAC
TGCACTCACG ACAACCCCTT GGAGACTCGG AACATCACCT TCTTTTCCAC CAACTGTGTG
GAAGGCACGG CTCGGGGCGT GGTGGTGGCC ACGGGCGACC GCACTGTCAT GGGCCGTATC
GCCACCCTGG CATCAGGGCT GGAGGTGGGC AAGACGCCCA TCGCCATCGA GATTGAGCAC
TTCATCCAGC TCATCACCGG CGTGGCTGTC TTCCTGGGTG TCTCCTTCTT CATCCTCTCC
CTCATTCTCG GATACACCTG GCTTGAGGCT GTCATCTTCC TCATCGGCAT CATCGTGGCC
AATGTCCCAG AGGGTCTGCT GGCCACTGTC ACTGTGTGTC TGACGCTGAC CGCCAAGCGC
ATGGCCCGGA AGAACTGCCT GGTGAAGAAC CTGGAGGCTG TAGAAACCCT GGGCTCCACG
TCCACCATCT GCTCAGATAA GACAGGGACC CTCACTCAGA ACCGCATGAC AGTCGCCCAC
ATGTGGTTTG ACAACCAGAT CCACGAGGCT GACACCACTG AGGACCAGTC AGGGACCTCA
TTTGACAAGA GTTCGCACAC CTGGGTGGCC CTGTCTCACA TCGCTGGGCT CTGCAATCGC
GCTGTCTTCA AGGGTGGTCA GGACAACATC CCTGTGCTCA AGAGGGATGT GGCTGGGGAT
GCGTCTGAGT CTGCCCTGCT CAAGTGCATC GAGCTGTCCT CTGGCTCCGT GAAGCTGATG
CGTGAACGCA ACAAGAAAGT GGCTGAGATT CCCTTCAATT CCACCAACAA ATACCAGCTC
TCCATCCATG AGACCGAGGA CCCCAACGAC AACCGATACC TGCTGGTGAT GAAGGGTGCC
CCCGAGCGCA TCCTGGACCG CTGCTCCACC ATCCTGCTAC AGGGCAAGGA GCAGCCTCTG
GACGAGGAAA TGAAGGAGGC CTTCCAGAAT GCCTACCTTG AGCTCGGTGG CCTGGGCGAG
CGCGTGCTTG GTTTCTGCCA TTATTACCTG CCCGAGGAGC AGTTCCCCAA GGGCTTTGCC
TTCGACTGTG ATGACGTGAA CTTCACCACG GACAACCTCT GCTTTGTGGG CCTCATGTCC
ATGATCGACC CACCCCGGGC AGCCGTCCCT GACGCGGTGG GCAAGTGTCG CAGCGCAGGC
ATCAAGGTCA TCATGGTCAC CGGCGATCAC CCCATCACGG CCAAGGCCAT TGCCAAGGGT
GTGGGCATCA TCTCTGAGGG CAACGAGACT GTGGAGGACA TCGCCGCCCG GCTCAACATT
CCCGTCAGCC AGGTTAACCC CCGGGATGCC AAGGCCTGCG TGATCCACGG CACCGACCTC
AAGGACTTCA CCTCCGAGCA AATCGACGAG ATCCTGCAGA ATCACACCGA GATCGTCTTC
GCCCGCACAT CCCCCCAGCA GAAGCTCATC ATTGTGGAGG GCTGTCAGAG ACAGGGTGCA
ATTGTGGCTG TGACCGGGGA TGGTGTGAAC GACTCCCCCG CTCTGAAGAA GGCCGACATT
GGGGTGGCCA TGGGCATCGC TGGCTCTGAC GTCTCCAAGC AGGCAGCTGA CATGATCCTG
CTGGACGACA ACTTTGCCTC CATCGTCACA GGGGTGGAGG AGGGCCGCCT GATCTTCGAC
AACCTAAAGA AGTCCATTGC CTACACCCTG ACCAGCAATA TCCCGGAGAT CACGCCCTTC
CTGCTGTTCA TCATGGCCAA CATCCCGCTG CCCCTGGGCA CCATCACCAT CCTCTGCATC
GATCTGGGCA CTGACATGGT CCCTGCCATC TCACTGGCGT ACGAGGCTGC CGAAAGCGAC
ATCATGAAGA GACAGCCCAG GAACCCGCGG ACGGACAAAT TGGTCAATGA GAGACTCATC
AGCATGGCCT ACGGGCAGAT TGGAATGATC CAGGCTCTCG GTGGCTTCTT CTCTTACTTT
GTGATCCTGG CAGAAAATGG CTTCTTGCCC GGCAACCTGG TGGGCATCCG GCTGAACTGG
GATGACCGCA CCGTCAATGA CCTGGAAGAC AGTTACGGGC AGCAGTGGAC ATACGAGCAG
AGGAAGGTGG TGGAGTTCAC CTGCCACACG GCCTTCTTTG TGAGCATCGT TGTCGTCCAG
TGGGCCGATC TGATCATCTG CAAGACCCGG AGGAACTCGG TCTTCCAGCA GGGCATGAAG
AACAAGATCC TGATCTTCGG GCTGTTTGAG GAGACGGCCC TGGCTGCCTT CCTGTCCTAC
TGCCCCGGCA TGGACGTGGC CCTGCGCATG TACCCTCTCA AGCCCAGCTG GTGGTTCTGT
GCCTTCCCCT ACAGTTTCCT CATCTTCGTC TACGACGAAA TCCGCAAACT CATCCTGCGC
AGGAACCCAG GGGGTTGGGT GGAGAAGGAA ACCTACTACT GA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_689509.1
CDS201..3242
Misc Feature(1)141..143(+)
Misc Feature(2)249..3239(+)
Misc Feature(3)288..512(+)
Misc Feature(4)414..422(+)
Misc Feature(5)432..494(+)
Misc Feature(6)564..626(+)
Misc Feature(7)573..1268(+)
Misc Feature(8)993..995(+)
Misc Feature(9)1035..1094(+)
Misc Feature(10)1131..1184(+)
Misc Feature(11)1449..1733(+)
Misc Feature(12)1842..1844(+)
Misc Feature(13)1884..2024(+)
Misc Feature(14)1884..1901(+)
Misc Feature(15)1986..2426(+)
Misc Feature(16)2019..2021(+)
Misc Feature(17)2487..2546(+)
Misc Feature(18)2565..3194(+)
Misc Feature(19)2577..2639(+)
Misc Feature(20)2700..2768(+)
Misc Feature(21)2925..2984(+)
Misc Feature(22)2997..2999(+)
Misc Feature(23)3024..3080(+)
Misc Feature(24)3126..3188(+)
Exon (1)1..206
Gene:ATP1A3
Gene Synonym:
Exon (2)207..293
Gene:ATP1A3
Gene Synonym:
Exon (3)294..353
Gene:ATP1A3
Gene Synonym:
Exon (4)354..557
Gene:ATP1A3
Gene Synonym:
Exon (5)558..671
Gene:ATP1A3
Gene Synonym:
Exon (6)672..806
Gene:ATP1A3
Gene Synonym:
Exon (7)807..924
Gene:ATP1A3
Gene Synonym:
Exon (8)925..1193
Gene:ATP1A3
Gene Synonym:
Exon (9)1194..1392
Gene:ATP1A3
Gene Synonym:
Exon (10)1393..1502
Gene:ATP1A3
Gene Synonym:
Exon (11)1503..1637
Gene:ATP1A3
Gene Synonym:
Exon (12)1638..1830
Gene:ATP1A3
Gene Synonym:
Exon (13)1831..2006
Gene:ATP1A3
Gene Synonym:
Exon (14)2007..2143
Gene:ATP1A3
Gene Synonym:
Exon (15)2144..2294
Gene:ATP1A3
Gene Synonym:
Exon (16)2295..2463
Gene:ATP1A3
Gene Synonym:
Exon (17)2464..2618
Gene:ATP1A3
Gene Synonym:
Exon (18)2619..2742
Gene:ATP1A3
Gene Synonym:
Exon (19)2743..2888
Gene:ATP1A3
Gene Synonym:
Exon (20)2889..3019
Gene:ATP1A3
Gene Synonym:
Exon (21)3020..3121
Gene:ATP1A3
Gene Synonym:
Exon (22)3122..3213
Gene:ATP1A3
Gene Synonym:
Exon (23)3214..3597
Gene:ATP1A3
Gene Synonym:
Translation
Position Chain Variation Link
53 53 g, t dbSNP:769525784
332 332 a, g dbSNP:199577046
407 407 a, c, t dbSNP:200616931
610 610 a, c, t dbSNP:542652468
619 619 a, t dbSNP:606231427
779 779 g, t dbSNP:200860753
866 866 a, g, t dbSNP:2217342
941 941 c, g, t dbSNP:767234141
1021 1021 a, c, t dbSNP:80356532
1029 1029 a, g dbSNP:80356533
1165 1165 a, t dbSNP:606231428
1176 1176 -, ctg dbSNP:397515578
1179 1179 -, ctg dbSNP:606231429
1198 1198 g, t dbSNP:606231430
1203 1203 a, c dbSNP:606231431
1272 1272 g, t dbSNP:606231432
1309 1309 a, c dbSNP:573535377
1312 1312 c, t dbSNP:606231433
1322 1322 c, t dbSNP:776748534
1344 1344 c, t dbSNP:606231448
1398 1398 a, t dbSNP:760884114
1450 1450 c, t dbSNP:606231449
1523 1523 a, g, t dbSNP:34578730
1719 1719 c, t dbSNP:749776123
2038 2038 c, t dbSNP:80356534
2214 2214 c, t dbSNP:267605506
2251 2251 c, t dbSNP:397515577
2313 2313 -, g dbSNP:371698459
2463 2463 a, g, t dbSNP:557052809
2464 2464 c, g dbSNP:606231434
2467 2467 a, g dbSNP:606231435
2470 2470 c, t dbSNP:606231436
2473 2473 g, t dbSNP:80356535
2512 2512 a, c, t dbSNP:557939077
2516 2516 a, c, g dbSNP:534926223
2518 2518 a, g, t dbSNP:606231437
2519 2519 c, t dbSNP:61733017
2538 2538 c, t dbSNP:80356536
2601 2601 a, g, t dbSNP:80356537
2611 2611 c, t dbSNP:606231438
2615 2615 c, g dbSNP:606231439
2617 2617 a, g, t dbSNP:549006436
2628 2628 a, t dbSNP:606231440
2629 2629 a, g, t dbSNP:536681257
2631 2631 c, t dbSNP:387907282
2643 2643 a, g dbSNP:387907281
2652 2652 a, g dbSNP:587777771
2800 2800 a, g dbSNP:606231442
2892 2892 c, t dbSNP:773848258
2955 2955 -, gtc dbSNP:606231443
2967 2967 a, g, t dbSNP:267606670
2980 2980 a, g, t dbSNP:606231444
2981 2981 c, g, t dbSNP:606231445
3039 3039 a, c, g dbSNP:398122887
3064 3064 a, c dbSNP:606231446
3174 3174 g, t dbSNP:606231447
3240 3240 -, act dbSNP:397515382
3281 3281 c, g dbSNP:919390
3295 3295 a, g dbSNP:776731215
3440 3440 -, ctc dbSNP:587778772
3478 3478 c, t dbSNP:199854166
3501 3501 c, t dbSNP:772022012

Target ORF information:

RefSeq Version NM_152296
Organism Homo sapiens (human)
Definition Homo sapiens ATPase, Na+/K+ transporting, alpha 3 polypeptide (ATP1A3), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_152296

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
ATGGGGGACA AGAAAGATGA CAAGGACTCA CCCAAGAAGA ACAAGGGCAA GGAGCGCCGG 
GACCTGGATG ACCTCAAGAA GGAGGTGGCT ATGACAGAGC ACAAGATGTC AGTGGAAGAG
GTCTGCCGGA AATACAACAC AGACTGTGTG CAGGGTTTGA CCCACAGCAA AGCCCAGGAG
ATCCTGGCCC GGGATGGGCC TAACGCACTC ACGCCACCGC CTACCACCCC AGAGTGGGTC
AAGTTTTGCC GGCAGCTCTT CGGGGGCTTC TCCATCCTGC TGTGGATCGG GGCTATCCTC
TGCTTCCTGG CCTACGGTAT CCAGGCGGGC ACCGAGGACG ACCCCTCTGG TGACAACCTG
TACCTGGGCA TCGTGCTGGC GGCCGTGGTG ATCATCACTG GCTGCTTCTC CTACTACCAG
GAGGCCAAGA GCTCCAAGAT CATGGAGTCC TTCAAGAACA TGGTGCCCCA GCAAGCCCTG
GTGATCCGGG AAGGTGAGAA GATGCAGGTG AACGCTGAGG AGGTGGTGGT CGGGGACCTG
GTGGAGATCA AGGGTGGAGA CCGAGTGCCA GCTGACCTGC GGATCATCTC AGCCCACGGC
TGCAAGGTGG ACAACTCCTC CCTGACTGGC GAATCCGAGC CCCAGACTCG CTCTCCCGAC
TGCACTCACG ACAACCCCTT GGAGACTCGG AACATCACCT TCTTTTCCAC CAACTGTGTG
GAAGGCACGG CTCGGGGCGT GGTGGTGGCC ACGGGCGACC GCACTGTCAT GGGCCGTATC
GCCACCCTGG CATCAGGGCT GGAGGTGGGC AAGACGCCCA TCGCCATCGA GATTGAGCAC
TTCATCCAGC TCATCACCGG CGTGGCTGTC TTCCTGGGTG TCTCCTTCTT CATCCTCTCC
CTCATTCTCG GATACACCTG GCTTGAGGCT GTCATCTTCC TCATCGGCAT CATCGTGGCC
AATGTCCCAG AGGGTCTGCT GGCCACTGTC ACTGTGTGTC TGACGCTGAC CGCCAAGCGC
ATGGCCCGGA AGAACTGCCT GGTGAAGAAC CTGGAGGCTG TAGAAACCCT GGGCTCCACG
TCCACCATCT GCTCAGATAA GACAGGGACC CTCACTCAGA ACCGCATGAC AGTCGCCCAC
ATGTGGTTTG ACAACCAGAT CCACGAGGCT GACACCACTG AGGACCAGTC AGGGACCTCA
TTTGACAAGA GTTCGCACAC CTGGGTGGCC CTGTCTCACA TCGCTGGGCT CTGCAATCGC
GCTGTCTTCA AGGGTGGTCA GGACAACATC CCTGTGCTCA AGAGGGATGT GGCTGGGGAT
GCGTCTGAGT CTGCCCTGCT CAAGTGCATC GAGCTGTCCT CTGGCTCCGT GAAGCTGATG
CGTGAACGCA ACAAGAAAGT GGCTGAGATT CCCTTCAATT CCACCAACAA ATACCAGCTC
TCCATCCATG AGACCGAGGA CCCCAACGAC AACCGATACC TGCTGGTGAT GAAGGGTGCC
CCCGAGCGCA TCCTGGACCG CTGCTCCACC ATCCTGCTAC AGGGCAAGGA GCAGCCTCTG
GACGAGGAAA TGAAGGAGGC CTTCCAGAAT GCCTACCTTG AGCTCGGTGG CCTGGGCGAG
CGCGTGCTTG GTTTCTGCCA TTATTACCTG CCCGAGGAGC AGTTCCCCAA GGGCTTTGCC
TTCGACTGTG ATGACGTGAA CTTCACCACG GACAACCTCT GCTTTGTGGG CCTCATGTCC
ATGATCGACC CACCCCGGGC AGCCGTCCCT GACGCGGTGG GCAAGTGTCG CAGCGCAGGC
ATCAAGGTCA TCATGGTCAC CGGCGATCAC CCCATCACGG CCAAGGCCAT TGCCAAGGGT
GTGGGCATCA TCTCTGAGGG CAACGAGACT GTGGAGGACA TCGCCGCCCG GCTCAACATT
CCCGTCAGCC AGGTTAACCC CCGGGATGCC AAGGCCTGCG TGATCCACGG CACCGACCTC
AAGGACTTCA CCTCCGAGCA AATCGACGAG ATCCTGCAGA ATCACACCGA GATCGTCTTC
GCCCGCACAT CCCCCCAGCA GAAGCTCATC ATTGTGGAGG GCTGTCAGAG ACAGGGTGCA
ATTGTGGCTG TGACCGGGGA TGGTGTGAAC GACTCCCCCG CTCTGAAGAA GGCCGACATT
GGGGTGGCCA TGGGCATCGC TGGCTCTGAC GTCTCCAAGC AGGCAGCTGA CATGATCCTG
CTGGACGACA ACTTTGCCTC CATCGTCACA GGGGTGGAGG AGGGCCGCCT GATCTTCGAC
AACCTAAAGA AGTCCATTGC CTACACCCTG ACCAGCAATA TCCCGGAGAT CACGCCCTTC
CTGCTGTTCA TCATGGCCAA CATCCCGCTG CCCCTGGGCA CCATCACCAT CCTCTGCATC
GATCTGGGCA CTGACATGGT CCCTGCCATC TCACTGGCGT ACGAGGCTGC CGAAAGCGAC
ATCATGAAGA GACAGCCCAG GAACCCGCGG ACGGACAAAT TGGTCAATGA GAGACTCATC
AGCATGGCCT ACGGGCAGAT TGGAATGATC CAGGCTCTCG GTGGCTTCTT CTCTTACTTT
GTGATCCTGG CAGAAAATGG CTTCTTGCCC GGCAACCTGG TGGGCATCCG GCTGAACTGG
GATGACCGCA CCGTCAATGA CCTGGAAGAC AGTTACGGGC AGCAGTGGAC ATACGAGCAG
AGGAAGGTGG TGGAGTTCAC CTGCCACACG GCCTTCTTTG TGAGCATCGT TGTCGTCCAG
TGGGCCGATC TGATCATCTG CAAGACCCGG AGGAACTCGG TCTTCCAGCA GGGCATGAAG
AACAAGATCC TGATCTTCGG GCTGTTTGAG GAGACGGCCC TGGCTGCCTT CCTGTCCTAC
TGCCCCGGCA TGGACGTGGC CCTGCGCATG TACCCTCTCA AGCCCAGCTG GTGGTTCTGT
GCCTTCCCCT ACAGTTTCCT CATCTTCGTC TACGACGAAA TCCGCAAACT CATCCTGCGC
AGGAACCCAG GGGGTTGGGT GGAGAAGGAA ACCTACTACT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26608
Accession Version NM_001256213.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3075bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product sodium/potassium-transporting ATPase subunit alpha-3 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK296557.1, AK223569.1, AK295078.1 and BC009282.2. Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]. Transcript Variant: This variant (2) has an alternate 5' exon, compared to variant 1. The resulting isoform (2) has a different and longer N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK296557.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
ATGGGAGGCT GGGAGGAGGA GAGGAACAGG AGAGCCACGG ACAAGAAAGA TGACAAGGAC 
TCACCCAAGA AGAACAAGGG CAAGGAGCGC CGGGACCTGG ATGACCTCAA GAAGGAGGTG
GCTATGACAG AGCACAAGAT GTCAGTGGAA GAGGTCTGCC GGAAATACAA CACAGACTGT
GTGCAGGGTT TGACCCACAG CAAAGCCCAG GAGATCCTGG CCCGGGATGG GCCTAACGCA
CTCACGCCAC CGCCTACCAC CCCAGAGTGG GTCAAGTTTT GCCGGCAGCT CTTCGGGGGC
TTCTCCATCC TGCTGTGGAT CGGGGCTATC CTCTGCTTCC TGGCCTACGG TATCCAGGCG
GGCACCGAGG ACGACCCCTC TGGTGACAAC CTGTACCTGG GCATCGTGCT GGCGGCCGTG
GTGATCATCA CTGGCTGCTT CTCCTACTAC CAGGAGGCCA AGAGCTCCAA GATCATGGAG
TCCTTCAAGA ACATGGTGCC CCAGCAAGCC CTGGTGATCC GGGAAGGTGA GAAGATGCAG
GTGAACGCTG AGGAGGTGGT GGTCGGGGAC CTGGTGGAGA TCAAGGGTGG AGACCGAGTG
CCAGCTGACC TGCGGATCAT CTCAGCCCAC GGCTGCAAGG TGGACAACTC CTCCCTGACT
GGCGAATCCG AGCCCCAGAC TCGCTCTCCC GACTGCACTC ACGACAACCC CTTGGAGACT
CGGAACATCA CCTTCTTTTC CACCAACTGT GTGGAAGGCA CGGCTCGGGG CGTGGTGGTG
GCCACGGGCG ACCGCACTGT CATGGGCCGT ATCGCCACCC TGGCATCAGG GCTGGAGGTG
GGCAAGACGC CCATCGCCAT CGAGATTGAG CACTTCATCC AGCTCATCAC CGGCGTGGCT
GTCTTCCTGG GTGTCTCCTT CTTCATCCTC TCCCTCATTC TCGGATACAC CTGGCTTGAG
GCTGTCATCT TCCTCATCGG CATCATCGTG GCCAATGTCC CAGAGGGTCT GCTGGCCACT
GTCACTGTGT GTCTGACGCT GACCGCCAAG CGCATGGCCC GGAAGAACTG CCTGGTGAAG
AACCTGGAGG CTGTAGAAAC CCTGGGCTCC ACGTCCACCA TCTGCTCAGA TAAGACAGGG
ACCCTCACTC AGAACCGCAT GACAGTCGCC CACATGTGGT TTGACAACCA GATCCACGAG
GCTGACACCA CTGAGGACCA GTCAGGGACC TCATTTGACA AGAGTTCGCA CACCTGGGTG
GCCCTGTCTC ACATCGCTGG GCTCTGCAAT CGCGCTGTCT TCAAGGGTGG TCAGGACAAC
ATCCCTGTGC TCAAGAGGGA TGTGGCTGGG GATGCGTCTG AGTCTGCCCT GCTCAAGTGC
ATCGAGCTGT CCTCTGGCTC CGTGAAGCTG ATGCGTGAAC GCAACAAGAA AGTGGCTGAG
ATTCCCTTCA ATTCCACCAA CAAATACCAG CTCTCCATCC ATGAGACCGA GGACCCCAAC
GACAACCGAT ACCTGCTGGT GATGAAGGGT GCCCCCGAGC GCATCCTGGA CCGCTGCTCC
ACCATCCTGC TACAGGGCAA GGAGCAGCCT CTGGACGAGG AAATGAAGGA GGCCTTCCAG
AATGCCTACC TTGAGCTCGG TGGCCTGGGC GAGCGCGTGC TTGGTTTCTG CCATTATTAC
CTGCCCGAGG AGCAGTTCCC CAAGGGCTTT GCCTTCGACT GTGATGACGT GAACTTCACC
ACGGACAACC TCTGCTTTGT GGGCCTCATG TCCATGATCG ACCCACCCCG GGCAGCCGTC
CCTGACGCGG TGGGCAAGTG TCGCAGCGCA GGCATCAAGG TCATCATGGT CACCGGCGAT
CACCCCATCA CGGCCAAGGC CATTGCCAAG GGTGTGGGCA TCATCTCTGA GGGCAACGAG
ACTGTGGAGG ACATCGCCGC CCGGCTCAAC ATTCCCGTCA GCCAGGTTAA CCCCCGGGAT
GCCAAGGCCT GCGTGATCCA CGGCACCGAC CTCAAGGACT TCACCTCCGA GCAAATCGAC
GAGATCCTGC AGAATCACAC CGAGATCGTC TTCGCCCGCA CATCCCCCCA GCAGAAGCTC
ATCATTGTGG AGGGCTGTCA GAGACAGGGT GCAATTGTGG CTGTGACCGG GGATGGTGTG
AACGACTCCC CCGCTCTGAA GAAGGCCGAC ATTGGGGTGG CCATGGGCAT CGCTGGCTCT
GACGTCTCCA AGCAGGCAGC TGACATGATC CTGCTGGACG ACAACTTTGC CTCCATCGTC
ACAGGGGTGG AGGAGGGCCG CCTGATCTTC GACAACCTAA AGAAGTCCAT TGCCTACACC
CTGACCAGCA ATATCCCGGA GATCACGCCC TTCCTGCTGT TCATCATGGC CAACATCCCG
CTGCCCCTGG GCACCATCAC CATCCTCTGC ATCGATCTGG GCACTGACAT GGTCCCTGCC
ATCTCACTGG CGTACGAGGC TGCCGAAAGC GACATCATGA AGAGACAGCC CAGGAACCCG
CGGACGGACA AATTGGTCAA TGAGAGACTC ATCAGCATGG CCTACGGGCA GATTGGAATG
ATCCAGGCTC TCGGTGGCTT CTTCTCTTAC TTTGTGATCC TGGCAGAAAA TGGCTTCTTG
CCCGGCAACC TGGTGGGCAT CCGGCTGAAC TGGGATGACC GCACCGTCAA TGACCTGGAA
GACAGTTACG GGCAGCAGTG GACATACGAG CAGAGGAAGG TGGTGGAGTT CACCTGCCAC
ACGGCCTTCT TTGTGAGCAT CGTTGTCGTC CAGTGGGCCG ATCTGATCAT CTGCAAGACC
CGGAGGAACT CGGTCTTCCA GCAGGGCATG AAGAACAAGA TCCTGATCTT CGGGCTGTTT
GAGGAGACGG CCCTGGCTGC CTTCCTGTCC TACTGCCCCG GCATGGACGT GGCCCTGCGC
ATGTACCCTC TCAAGCCCAG CTGGTGGTTC TGTGCCTTCC CCTACAGTTT CCTCATCTTC
GTCTACGACG AAATCCGCAA ACTCATCCTG CGCAGGAACC CAGGGGGTTG GGTGGAGAAG
GAAACCTACT ACTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001243142.1
CDS37..3111
Misc Feature(1)118..3108(+)
Misc Feature(2)157..381(+)
Misc Feature(3)442..1137(+)
Misc Feature(4)1318..1602(+)
Misc Feature(5)1753..1893(+)
Misc Feature(6)1753..1770(+)
Misc Feature(7)1855..2295(+)
Misc Feature(8)1888..1890(+)
Misc Feature(9)2434..3063(+)
Exon (1)1..75
Gene:ATP1A3
Gene Synonym:
Exon (2)76..162
Gene:ATP1A3
Gene Synonym:
Exon (3)163..222
Gene:ATP1A3
Gene Synonym:
Exon (4)223..426
Gene:ATP1A3
Gene Synonym:
Exon (5)427..540
Gene:ATP1A3
Gene Synonym:
Exon (6)541..675
Gene:ATP1A3
Gene Synonym:
Exon (7)676..793
Gene:ATP1A3
Gene Synonym:
Exon (8)794..1062
Gene:ATP1A3
Gene Synonym:
Exon (9)1063..1261
Gene:ATP1A3
Gene Synonym:
Exon (10)1262..1371
Gene:ATP1A3
Gene Synonym:
Exon (11)1372..1506
Gene:ATP1A3
Gene Synonym:
Exon (12)1507..1699
Gene:ATP1A3
Gene Synonym:
Exon (13)1700..1875
Gene:ATP1A3
Gene Synonym:
Exon (14)1876..2012
Gene:ATP1A3
Gene Synonym:
Exon (15)2013..2163
Gene:ATP1A3
Gene Synonym:
Exon (16)2164..2332
Gene:ATP1A3
Gene Synonym:
Exon (17)2333..2487
Gene:ATP1A3
Gene Synonym:
Exon (18)2488..2611
Gene:ATP1A3
Gene Synonym:
Exon (19)2612..2757
Gene:ATP1A3
Gene Synonym:
Exon (20)2758..2888
Gene:ATP1A3
Gene Synonym:
Exon (21)2889..2990
Gene:ATP1A3
Gene Synonym:
Exon (22)2991..3082
Gene:ATP1A3
Gene Synonym:
Exon (23)3083..3466
Gene:ATP1A3
Gene Synonym:
Translation
Position Chain Variation Link
10 10 -, tg dbSNP:148508295
65 65 a, g dbSNP:12976997
201 201 a, g dbSNP:199577046
276 276 a, c, t dbSNP:200616931
479 479 a, c, t dbSNP:542652468
488 488 a, t dbSNP:606231427
648 648 g, t dbSNP:200860753
735 735 a, g, t dbSNP:2217342
810 810 c, g, t dbSNP:767234141
890 890 a, c, t dbSNP:80356532
898 898 a, g dbSNP:80356533
1034 1034 a, t dbSNP:606231428
1045 1045 -, ctg dbSNP:397515578
1048 1048 -, ctg dbSNP:606231429
1067 1067 g, t dbSNP:606231430
1072 1072 a, c dbSNP:606231431
1141 1141 g, t dbSNP:606231432
1178 1178 a, c dbSNP:573535377
1181 1181 c, t dbSNP:606231433
1191 1191 c, t dbSNP:776748534
1213 1213 c, t dbSNP:606231448
1267 1267 a, t dbSNP:760884114
1319 1319 c, t dbSNP:606231449
1392 1392 a, g, t dbSNP:34578730
1588 1588 c, t dbSNP:749776123
1907 1907 c, t dbSNP:80356534
2083 2083 c, t dbSNP:267605506
2120 2120 c, t dbSNP:397515577
2182 2182 -, g dbSNP:371698459
2332 2332 a, g, t dbSNP:557052809
2333 2333 c, g dbSNP:606231434
2336 2336 a, g dbSNP:606231435
2339 2339 c, t dbSNP:606231436
2342 2342 g, t dbSNP:80356535
2381 2381 a, c, t dbSNP:557939077
2385 2385 a, c, g dbSNP:534926223
2387 2387 a, g, t dbSNP:606231437
2388 2388 c, t dbSNP:61733017
2407 2407 c, t dbSNP:80356536
2470 2470 a, g, t dbSNP:80356537
2480 2480 c, t dbSNP:606231438
2484 2484 c, g dbSNP:606231439
2486 2486 a, g, t dbSNP:549006436
2497 2497 a, t dbSNP:606231440
2498 2498 a, g, t dbSNP:536681257
2500 2500 c, t dbSNP:387907282
2512 2512 a, g dbSNP:387907281
2521 2521 a, g dbSNP:587777771
2669 2669 a, g dbSNP:606231442
2761 2761 c, t dbSNP:773848258
2824 2824 -, gtc dbSNP:606231443
2836 2836 a, g, t dbSNP:267606670
2849 2849 a, g, t dbSNP:606231444
2850 2850 c, g, t dbSNP:606231445
2908 2908 a, c, g dbSNP:398122887
2933 2933 a, c dbSNP:606231446
3043 3043 g, t dbSNP:606231447
3109 3109 -, act dbSNP:397515382
3150 3150 c, g dbSNP:919390
3164 3164 a, g dbSNP:776731215
3309 3309 -, ctc dbSNP:587778772
3347 3347 c, t dbSNP:199854166
3370 3370 c, t dbSNP:772022012

Target ORF information:

RefSeq Version NM_001256213
Organism Homo sapiens (human)
Definition Homo sapiens ATPase, Na+/K+ transporting, alpha 3 polypeptide (ATP1A3), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001256213

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
ATGGGAGGCT GGGAGGAGGA GAGGAACAGG AGAGCCACGG ACAAGAAAGA TGACAAGGAC 
TCACCCAAGA AGAACAAGGG CAAGGAGCGC CGGGACCTGG ATGACCTCAA GAAGGAGGTG
GCTATGACAG AGCACAAGAT GTCAGTGGAA GAGGTCTGCC GGAAATACAA CACAGACTGT
GTGCAGGGTT TGACCCACAG CAAAGCCCAG GAGATCCTGG CCCGGGATGG GCCTAACGCA
CTCACGCCAC CGCCTACCAC CCCAGAGTGG GTCAAGTTTT GCCGGCAGCT CTTCGGGGGC
TTCTCCATCC TGCTGTGGAT CGGGGCTATC CTCTGCTTCC TGGCCTACGG TATCCAGGCG
GGCACCGAGG ACGACCCCTC TGGTGACAAC CTGTACCTGG GCATCGTGCT GGCGGCCGTG
GTGATCATCA CTGGCTGCTT CTCCTACTAC CAGGAGGCCA AGAGCTCCAA GATCATGGAG
TCCTTCAAGA ACATGGTGCC CCAGCAAGCC CTGGTGATCC GGGAAGGTGA GAAGATGCAG
GTGAACGCTG AGGAGGTGGT GGTCGGGGAC CTGGTGGAGA TCAAGGGTGG AGACCGAGTG
CCAGCTGACC TGCGGATCAT CTCAGCCCAC GGCTGCAAGG TGGACAACTC CTCCCTGACT
GGCGAATCCG AGCCCCAGAC TCGCTCTCCC GACTGCACTC ACGACAACCC CTTGGAGACT
CGGAACATCA CCTTCTTTTC CACCAACTGT GTGGAAGGCA CGGCTCGGGG CGTGGTGGTG
GCCACGGGCG ACCGCACTGT CATGGGCCGT ATCGCCACCC TGGCATCAGG GCTGGAGGTG
GGCAAGACGC CCATCGCCAT CGAGATTGAG CACTTCATCC AGCTCATCAC CGGCGTGGCT
GTCTTCCTGG GTGTCTCCTT CTTCATCCTC TCCCTCATTC TCGGATACAC CTGGCTTGAG
GCTGTCATCT TCCTCATCGG CATCATCGTG GCCAATGTCC CAGAGGGTCT GCTGGCCACT
GTCACTGTGT GTCTGACGCT GACCGCCAAG CGCATGGCCC GGAAGAACTG CCTGGTGAAG
AACCTGGAGG CTGTAGAAAC CCTGGGCTCC ACGTCCACCA TCTGCTCAGA TAAGACAGGG
ACCCTCACTC AGAACCGCAT GACAGTCGCC CACATGTGGT TTGACAACCA GATCCACGAG
GCTGACACCA CTGAGGACCA GTCAGGGACC TCATTTGACA AGAGTTCGCA CACCTGGGTG
GCCCTGTCTC ACATCGCTGG GCTCTGCAAT CGCGCTGTCT TCAAGGGTGG TCAGGACAAC
ATCCCTGTGC TCAAGAGGGA TGTGGCTGGG GATGCGTCTG AGTCTGCCCT GCTCAAGTGC
ATCGAGCTGT CCTCTGGCTC CGTGAAGCTG ATGCGTGAAC GCAACAAGAA AGTGGCTGAG
ATTCCCTTCA ATTCCACCAA CAAATACCAG CTCTCCATCC ATGAGACCGA GGACCCCAAC
GACAACCGAT ACCTGCTGGT GATGAAGGGT GCCCCCGAGC GCATCCTGGA CCGCTGCTCC
ACCATCCTGC TACAGGGCAA GGAGCAGCCT CTGGACGAGG AAATGAAGGA GGCCTTCCAG
AATGCCTACC TTGAGCTCGG TGGCCTGGGC GAGCGCGTGC TTGGTTTCTG CCATTATTAC
CTGCCCGAGG AGCAGTTCCC CAAGGGCTTT GCCTTCGACT GTGATGACGT GAACTTCACC
ACGGACAACC TCTGCTTTGT GGGCCTCATG TCCATGATCG ACCCACCCCG GGCAGCCGTC
CCTGACGCGG TGGGCAAGTG TCGCAGCGCA GGCATCAAGG TCATCATGGT CACCGGCGAT
CACCCCATCA CGGCCAAGGC CATTGCCAAG GGTGTGGGCA TCATCTCTGA GGGCAACGAG
ACTGTGGAGG ACATCGCCGC CCGGCTCAAC ATTCCCGTCA GCCAGGTTAA CCCCCGGGAT
GCCAAGGCCT GCGTGATCCA CGGCACCGAC CTCAAGGACT TCACCTCCGA GCAAATCGAC
GAGATCCTGC AGAATCACAC CGAGATCGTC TTCGCCCGCA CATCCCCCCA GCAGAAGCTC
ATCATTGTGG AGGGCTGTCA GAGACAGGGT GCAATTGTGG CTGTGACCGG GGATGGTGTG
AACGACTCCC CCGCTCTGAA GAAGGCCGAC ATTGGGGTGG CCATGGGCAT CGCTGGCTCT
GACGTCTCCA AGCAGGCAGC TGACATGATC CTGCTGGACG ACAACTTTGC CTCCATCGTC
ACAGGGGTGG AGGAGGGCCG CCTGATCTTC GACAACCTAA AGAAGTCCAT TGCCTACACC
CTGACCAGCA ATATCCCGGA GATCACGCCC TTCCTGCTGT TCATCATGGC CAACATCCCG
CTGCCCCTGG GCACCATCAC CATCCTCTGC ATCGATCTGG GCACTGACAT GGTCCCTGCC
ATCTCACTGG CGTACGAGGC TGCCGAAAGC GACATCATGA AGAGACAGCC CAGGAACCCG
CGGACGGACA AATTGGTCAA TGAGAGACTC ATCAGCATGG CCTACGGGCA GATTGGAATG
ATCCAGGCTC TCGGTGGCTT CTTCTCTTAC TTTGTGATCC TGGCAGAAAA TGGCTTCTTG
CCCGGCAACC TGGTGGGCAT CCGGCTGAAC TGGGATGACC GCACCGTCAA TGACCTGGAA
GACAGTTACG GGCAGCAGTG GACATACGAG CAGAGGAAGG TGGTGGAGTT CACCTGCCAC
ACGGCCTTCT TTGTGAGCAT CGTTGTCGTC CAGTGGGCCG ATCTGATCAT CTGCAAGACC
CGGAGGAACT CGGTCTTCCA GCAGGGCATG AAGAACAAGA TCCTGATCTT CGGGCTGTTT
GAGGAGACGG CCCTGGCTGC CTTCCTGTCC TACTGCCCCG GCATGGACGT GGCCCTGCGC
ATGTACCCTC TCAAGCCCAG CTGGTGGTTC TGTGCCTTCC CCTACAGTTT CCTCATCTTC
GTCTACGACG AAATCCGCAA ACTCATCCTG CGCAGGAACC CAGGGGGTTG GGTGGAGAAG
GAAACCTACT ACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27445
Accession Version NM_001256214.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3081bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product sodium/potassium-transporting ATPase subunit alpha-3 isoform 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB482528.1, AK295078.1, AK223569.1 and BC009282.2. Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]. Transcript Variant: This variant (3) has an additional in-frame segment in the 5' coding region, compared to variant 1. The resulting isoform (3) is longer than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK295078.1, AK316069.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962346 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
ATGGGGTCTG GTGGCTCTGA CAGCTATCGT ATCGCCACCT CGCAGGACAA GAAAGATGAC 
AAGGACTCAC CCAAGAAGAA CAAGGGCAAG GAGCGCCGGG ACCTGGATGA CCTCAAGAAG
GAGGTGGCTA TGACAGAGCA CAAGATGTCA GTGGAAGAGG TCTGCCGGAA ATACAACACA
GACTGTGTGC AGGGTTTGAC CCACAGCAAA GCCCAGGAGA TCCTGGCCCG GGATGGGCCT
AACGCACTCA CGCCACCGCC TACCACCCCA GAGTGGGTCA AGTTTTGCCG GCAGCTCTTC
GGGGGCTTCT CCATCCTGCT GTGGATCGGG GCTATCCTCT GCTTCCTGGC CTACGGTATC
CAGGCGGGCA CCGAGGACGA CCCCTCTGGT GACAACCTGT ACCTGGGCAT CGTGCTGGCG
GCCGTGGTGA TCATCACTGG CTGCTTCTCC TACTACCAGG AGGCCAAGAG CTCCAAGATC
ATGGAGTCCT TCAAGAACAT GGTGCCCCAG CAAGCCCTGG TGATCCGGGA AGGTGAGAAG
ATGCAGGTGA ACGCTGAGGA GGTGGTGGTC GGGGACCTGG TGGAGATCAA GGGTGGAGAC
CGAGTGCCAG CTGACCTGCG GATCATCTCA GCCCACGGCT GCAAGGTGGA CAACTCCTCC
CTGACTGGCG AATCCGAGCC CCAGACTCGC TCTCCCGACT GCACTCACGA CAACCCCTTG
GAGACTCGGA ACATCACCTT CTTTTCCACC AACTGTGTGG AAGGCACGGC TCGGGGCGTG
GTGGTGGCCA CGGGCGACCG CACTGTCATG GGCCGTATCG CCACCCTGGC ATCAGGGCTG
GAGGTGGGCA AGACGCCCAT CGCCATCGAG ATTGAGCACT TCATCCAGCT CATCACCGGC
GTGGCTGTCT TCCTGGGTGT CTCCTTCTTC ATCCTCTCCC TCATTCTCGG ATACACCTGG
CTTGAGGCTG TCATCTTCCT CATCGGCATC ATCGTGGCCA ATGTCCCAGA GGGTCTGCTG
GCCACTGTCA CTGTGTGTCT GACGCTGACC GCCAAGCGCA TGGCCCGGAA GAACTGCCTG
GTGAAGAACC TGGAGGCTGT AGAAACCCTG GGCTCCACGT CCACCATCTG CTCAGATAAG
ACAGGGACCC TCACTCAGAA CCGCATGACA GTCGCCCACA TGTGGTTTGA CAACCAGATC
CACGAGGCTG ACACCACTGA GGACCAGTCA GGGACCTCAT TTGACAAGAG TTCGCACACC
TGGGTGGCCC TGTCTCACAT CGCTGGGCTC TGCAATCGCG CTGTCTTCAA GGGTGGTCAG
GACAACATCC CTGTGCTCAA GAGGGATGTG GCTGGGGATG CGTCTGAGTC TGCCCTGCTC
AAGTGCATCG AGCTGTCCTC TGGCTCCGTG AAGCTGATGC GTGAACGCAA CAAGAAAGTG
GCTGAGATTC CCTTCAATTC CACCAACAAA TACCAGCTCT CCATCCATGA GACCGAGGAC
CCCAACGACA ACCGATACCT GCTGGTGATG AAGGGTGCCC CCGAGCGCAT CCTGGACCGC
TGCTCCACCA TCCTGCTACA GGGCAAGGAG CAGCCTCTGG ACGAGGAAAT GAAGGAGGCC
TTCCAGAATG CCTACCTTGA GCTCGGTGGC CTGGGCGAGC GCGTGCTTGG TTTCTGCCAT
TATTACCTGC CCGAGGAGCA GTTCCCCAAG GGCTTTGCCT TCGACTGTGA TGACGTGAAC
TTCACCACGG ACAACCTCTG CTTTGTGGGC CTCATGTCCA TGATCGACCC ACCCCGGGCA
GCCGTCCCTG ACGCGGTGGG CAAGTGTCGC AGCGCAGGCA TCAAGGTCAT CATGGTCACC
GGCGATCACC CCATCACGGC CAAGGCCATT GCCAAGGGTG TGGGCATCAT CTCTGAGGGC
AACGAGACTG TGGAGGACAT CGCCGCCCGG CTCAACATTC CCGTCAGCCA GGTTAACCCC
CGGGATGCCA AGGCCTGCGT GATCCACGGC ACCGACCTCA AGGACTTCAC CTCCGAGCAA
ATCGACGAGA TCCTGCAGAA TCACACCGAG ATCGTCTTCG CCCGCACATC CCCCCAGCAG
AAGCTCATCA TTGTGGAGGG CTGTCAGAGA CAGGGTGCAA TTGTGGCTGT GACCGGGGAT
GGTGTGAACG ACTCCCCCGC TCTGAAGAAG GCCGACATTG GGGTGGCCAT GGGCATCGCT
GGCTCTGACG TCTCCAAGCA GGCAGCTGAC ATGATCCTGC TGGACGACAA CTTTGCCTCC
ATCGTCACAG GGGTGGAGGA GGGCCGCCTG ATCTTCGACA ACCTAAAGAA GTCCATTGCC
TACACCCTGA CCAGCAATAT CCCGGAGATC ACGCCCTTCC TGCTGTTCAT CATGGCCAAC
ATCCCGCTGC CCCTGGGCAC CATCACCATC CTCTGCATCG ATCTGGGCAC TGACATGGTC
CCTGCCATCT CACTGGCGTA CGAGGCTGCC GAAAGCGACA TCATGAAGAG ACAGCCCAGG
AACCCGCGGA CGGACAAATT GGTCAATGAG AGACTCATCA GCATGGCCTA CGGGCAGATT
GGAATGATCC AGGCTCTCGG TGGCTTCTTC TCTTACTTTG TGATCCTGGC AGAAAATGGC
TTCTTGCCCG GCAACCTGGT GGGCATCCGG CTGAACTGGG ATGACCGCAC CGTCAATGAC
CTGGAAGACA GTTACGGGCA GCAGTGGACA TACGAGCAGA GGAAGGTGGT GGAGTTCACC
TGCCACACGG CCTTCTTTGT GAGCATCGTT GTCGTCCAGT GGGCCGATCT GATCATCTGC
AAGACCCGGA GGAACTCGGT CTTCCAGCAG GGCATGAAGA ACAAGATCCT GATCTTCGGG
CTGTTTGAGG AGACGGCCCT GGCTGCCTTC CTGTCCTACT GCCCCGGCAT GGACGTGGCC
CTGCGCATGT ACCCTCTCAA GCCCAGCTGG TGGTTCTGTG CCTTCCCCTA CAGTTTCCTC
ATCTTCGTCT ACGACGAAAT CCGCAAACTC ATCCTGCGCA GGAACCCAGG GGGTTGGGTG
GAGAAGGAAA CCTACTACTG A
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001243143.1
CDS201..3281
Misc Feature(1)141..143(+)
Misc Feature(2)288..3278(+)
Misc Feature(3)327..551(+)
Misc Feature(4)612..1307(+)
Misc Feature(5)1488..1772(+)
Misc Feature(6)1923..2063(+)
Misc Feature(7)1923..1940(+)
Misc Feature(8)2025..2465(+)
Misc Feature(9)2058..2060(+)
Misc Feature(10)2604..3233(+)
Exon (1)1..206
Gene:ATP1A3
Gene Synonym:
Exon (2)207..332
Gene:ATP1A3
Gene Synonym:
Exon (3)333..392
Gene:ATP1A3
Gene Synonym:
Exon (4)393..596
Gene:ATP1A3
Gene Synonym:
Exon (5)597..710
Gene:ATP1A3
Gene Synonym:
Exon (6)711..845
Gene:ATP1A3
Gene Synonym:
Exon (7)846..963
Gene:ATP1A3
Gene Synonym:
Exon (8)964..1232
Gene:ATP1A3
Gene Synonym:
Exon (9)1233..1431
Gene:ATP1A3
Gene Synonym:
Exon (10)1432..1541
Gene:ATP1A3
Gene Synonym:
Exon (11)1542..1676
Gene:ATP1A3
Gene Synonym:
Exon (12)1677..1869
Gene:ATP1A3
Gene Synonym:
Exon (13)1870..2045
Gene:ATP1A3
Gene Synonym:
Exon (14)2046..2182
Gene:ATP1A3
Gene Synonym:
Exon (15)2183..2333
Gene:ATP1A3
Gene Synonym:
Exon (16)2334..2502
Gene:ATP1A3
Gene Synonym:
Exon (17)2503..2657
Gene:ATP1A3
Gene Synonym:
Exon (18)2658..2781
Gene:ATP1A3
Gene Synonym:
Exon (19)2782..2927
Gene:ATP1A3
Gene Synonym:
Exon (20)2928..3058
Gene:ATP1A3
Gene Synonym:
Exon (21)3059..3160
Gene:ATP1A3
Gene Synonym:
Exon (22)3161..3252
Gene:ATP1A3
Gene Synonym:
Exon (23)3253..3636
Gene:ATP1A3
Gene Synonym:
Translation
Position Chain Variation Link
53 53 g, t dbSNP:769525784
371 371 a, g dbSNP:199577046
446 446 a, c, t dbSNP:200616931
649 649 a, c, t dbSNP:542652468
658 658 a, t dbSNP:606231427
818 818 g, t dbSNP:200860753
905 905 a, g, t dbSNP:2217342
980 980 c, g, t dbSNP:767234141
1060 1060 a, c, t dbSNP:80356532
1068 1068 a, g dbSNP:80356533
1204 1204 a, t dbSNP:606231428
1215 1215 -, ctg dbSNP:397515578
1218 1218 -, ctg dbSNP:606231429
1237 1237 g, t dbSNP:606231430
1242 1242 a, c dbSNP:606231431
1311 1311 g, t dbSNP:606231432
1348 1348 a, c dbSNP:573535377
1351 1351 c, t dbSNP:606231433
1361 1361 c, t dbSNP:776748534
1383 1383 c, t dbSNP:606231448
1437 1437 a, t dbSNP:760884114
1489 1489 c, t dbSNP:606231449
1562 1562 a, g, t dbSNP:34578730
1758 1758 c, t dbSNP:749776123
2077 2077 c, t dbSNP:80356534
2253 2253 c, t dbSNP:267605506
2290 2290 c, t dbSNP:397515577
2352 2352 -, g dbSNP:371698459
2502 2502 a, g, t dbSNP:557052809
2503 2503 c, g dbSNP:606231434
2506 2506 a, g dbSNP:606231435
2509 2509 c, t dbSNP:606231436
2512 2512 g, t dbSNP:80356535
2551 2551 a, c, t dbSNP:557939077
2555 2555 a, c, g dbSNP:534926223
2557 2557 a, g, t dbSNP:606231437
2558 2558 c, t dbSNP:61733017
2577 2577 c, t dbSNP:80356536
2640 2640 a, g, t dbSNP:80356537
2650 2650 c, t dbSNP:606231438
2654 2654 c, g dbSNP:606231439
2656 2656 a, g, t dbSNP:549006436
2667 2667 a, t dbSNP:606231440
2668 2668 a, g, t dbSNP:536681257
2670 2670 c, t dbSNP:387907282
2682 2682 a, g dbSNP:387907281
2691 2691 a, g dbSNP:587777771
2839 2839 a, g dbSNP:606231442
2931 2931 c, t dbSNP:773848258
2994 2994 -, gtc dbSNP:606231443
3006 3006 a, g, t dbSNP:267606670
3019 3019 a, g, t dbSNP:606231444
3020 3020 c, g, t dbSNP:606231445
3078 3078 a, c, g dbSNP:398122887
3103 3103 a, c dbSNP:606231446
3213 3213 g, t dbSNP:606231447
3279 3279 -, act dbSNP:397515382
3320 3320 c, g dbSNP:919390
3334 3334 a, g dbSNP:776731215
3479 3479 -, ctc dbSNP:587778772
3517 3517 c, t dbSNP:199854166
3540 3540 c, t dbSNP:772022012

Target ORF information:

RefSeq Version NM_001256214
Organism Homo sapiens (human)
Definition Homo sapiens ATPase, Na+/K+ transporting, alpha 3 polypeptide (ATP1A3), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001256214

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
ATGGGGTCTG GTGGCTCTGA CAGCTATCGT ATCGCCACCT CGCAGGACAA GAAAGATGAC 
AAGGACTCAC CCAAGAAGAA CAAGGGCAAG GAGCGCCGGG ACCTGGATGA CCTCAAGAAG
GAGGTGGCTA TGACAGAGCA CAAGATGTCA GTGGAAGAGG TCTGCCGGAA ATACAACACA
GACTGTGTGC AGGGTTTGAC CCACAGCAAA GCCCAGGAGA TCCTGGCCCG GGATGGGCCT
AACGCACTCA CGCCACCGCC TACCACCCCA GAGTGGGTCA AGTTTTGCCG GCAGCTCTTC
GGGGGCTTCT CCATCCTGCT GTGGATCGGG GCTATCCTCT GCTTCCTGGC CTACGGTATC
CAGGCGGGCA CCGAGGACGA CCCCTCTGGT GACAACCTGT ACCTGGGCAT CGTGCTGGCG
GCCGTGGTGA TCATCACTGG CTGCTTCTCC TACTACCAGG AGGCCAAGAG CTCCAAGATC
ATGGAGTCCT TCAAGAACAT GGTGCCCCAG CAAGCCCTGG TGATCCGGGA AGGTGAGAAG
ATGCAGGTGA ACGCTGAGGA GGTGGTGGTC GGGGACCTGG TGGAGATCAA GGGTGGAGAC
CGAGTGCCAG CTGACCTGCG GATCATCTCA GCCCACGGCT GCAAGGTGGA CAACTCCTCC
CTGACTGGCG AATCCGAGCC CCAGACTCGC TCTCCCGACT GCACTCACGA CAACCCCTTG
GAGACTCGGA ACATCACCTT CTTTTCCACC AACTGTGTGG AAGGCACGGC TCGGGGCGTG
GTGGTGGCCA CGGGCGACCG CACTGTCATG GGCCGTATCG CCACCCTGGC ATCAGGGCTG
GAGGTGGGCA AGACGCCCAT CGCCATCGAG ATTGAGCACT TCATCCAGCT CATCACCGGC
GTGGCTGTCT TCCTGGGTGT CTCCTTCTTC ATCCTCTCCC TCATTCTCGG ATACACCTGG
CTTGAGGCTG TCATCTTCCT CATCGGCATC ATCGTGGCCA ATGTCCCAGA GGGTCTGCTG
GCCACTGTCA CTGTGTGTCT GACGCTGACC GCCAAGCGCA TGGCCCGGAA GAACTGCCTG
GTGAAGAACC TGGAGGCTGT AGAAACCCTG GGCTCCACGT CCACCATCTG CTCAGATAAG
ACAGGGACCC TCACTCAGAA CCGCATGACA GTCGCCCACA TGTGGTTTGA CAACCAGATC
CACGAGGCTG ACACCACTGA GGACCAGTCA GGGACCTCAT TTGACAAGAG TTCGCACACC
TGGGTGGCCC TGTCTCACAT CGCTGGGCTC TGCAATCGCG CTGTCTTCAA GGGTGGTCAG
GACAACATCC CTGTGCTCAA GAGGGATGTG GCTGGGGATG CGTCTGAGTC TGCCCTGCTC
AAGTGCATCG AGCTGTCCTC TGGCTCCGTG AAGCTGATGC GTGAACGCAA CAAGAAAGTG
GCTGAGATTC CCTTCAATTC CACCAACAAA TACCAGCTCT CCATCCATGA GACCGAGGAC
CCCAACGACA ACCGATACCT GCTGGTGATG AAGGGTGCCC CCGAGCGCAT CCTGGACCGC
TGCTCCACCA TCCTGCTACA GGGCAAGGAG CAGCCTCTGG ACGAGGAAAT GAAGGAGGCC
TTCCAGAATG CCTACCTTGA GCTCGGTGGC CTGGGCGAGC GCGTGCTTGG TTTCTGCCAT
TATTACCTGC CCGAGGAGCA GTTCCCCAAG GGCTTTGCCT TCGACTGTGA TGACGTGAAC
TTCACCACGG ACAACCTCTG CTTTGTGGGC CTCATGTCCA TGATCGACCC ACCCCGGGCA
GCCGTCCCTG ACGCGGTGGG CAAGTGTCGC AGCGCAGGCA TCAAGGTCAT CATGGTCACC
GGCGATCACC CCATCACGGC CAAGGCCATT GCCAAGGGTG TGGGCATCAT CTCTGAGGGC
AACGAGACTG TGGAGGACAT CGCCGCCCGG CTCAACATTC CCGTCAGCCA GGTTAACCCC
CGGGATGCCA AGGCCTGCGT GATCCACGGC ACCGACCTCA AGGACTTCAC CTCCGAGCAA
ATCGACGAGA TCCTGCAGAA TCACACCGAG ATCGTCTTCG CCCGCACATC CCCCCAGCAG
AAGCTCATCA TTGTGGAGGG CTGTCAGAGA CAGGGTGCAA TTGTGGCTGT GACCGGGGAT
GGTGTGAACG ACTCCCCCGC TCTGAAGAAG GCCGACATTG GGGTGGCCAT GGGCATCGCT
GGCTCTGACG TCTCCAAGCA GGCAGCTGAC ATGATCCTGC TGGACGACAA CTTTGCCTCC
ATCGTCACAG GGGTGGAGGA GGGCCGCCTG ATCTTCGACA ACCTAAAGAA GTCCATTGCC
TACACCCTGA CCAGCAATAT CCCGGAGATC ACGCCCTTCC TGCTGTTCAT CATGGCCAAC
ATCCCGCTGC CCCTGGGCAC CATCACCATC CTCTGCATCG ATCTGGGCAC TGACATGGTC
CCTGCCATCT CACTGGCGTA CGAGGCTGCC GAAAGCGACA TCATGAAGAG ACAGCCCAGG
AACCCGCGGA CGGACAAATT GGTCAATGAG AGACTCATCA GCATGGCCTA CGGGCAGATT
GGAATGATCC AGGCTCTCGG TGGCTTCTTC TCTTACTTTG TGATCCTGGC AGAAAATGGC
TTCTTGCCCG GCAACCTGGT GGGCATCCGG CTGAACTGGG ATGACCGCAC CGTCAATGAC
CTGGAAGACA GTTACGGGCA GCAGTGGACA TACGAGCAGA GGAAGGTGGT GGAGTTCACC
TGCCACACGG CCTTCTTTGT GAGCATCGTT GTCGTCCAGT GGGCCGATCT GATCATCTGC
AAGACCCGGA GGAACTCGGT CTTCCAGCAG GGCATGAAGA ACAAGATCCT GATCTTCGGG
CTGTTTGAGG AGACGGCCCT GGCTGCCTTC CTGTCCTACT GCCCCGGCAT GGACGTGGCC
CTGCGCATGT ACCCTCTCAA GCCCAGCTGG TGGTTCTGTG CCTTCCCCTA CAGTTTCCTC
ATCTTCGTCT ACGACGAAAT CCGCAAACTC ATCCTGCGCA GGAACCCAGG GGGTTGGGTG
GAGAAGGAAA CCTACTACTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.