The following NFKBIA gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NFKBIA gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 954bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||NF-kappa-B inhibitor alpha
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AL133163.3, BC004983.1 and
This sequence is a reference standard in the RefSeqGene project.
On Feb 23, 2008 this sequence version replaced gi:10092618.
Summary: This gene encodes a member of the NF-kappa-B inhibitor
family, which contain multiple ankrin repeat domains. The encoded
protein interacts with REL dimers to inhibit NF-kappa-B/REL
complexes which are involved in inflammatory responses. The encoded
protein moves between the cytoplasm and the nucleus via a nuclear
localization signal and CRM1-mediated nuclear export. Mutations in
this gene have been found in ectodermal dysplasia anhidrotic with
T-cell immunodeficiency autosomal dominant disease. [provided by
RefSeq, Aug 2011].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BC002601.2, M69043.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.