The following ATP1B1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ATP1B1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 912bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||sodium/potassium-transporting ATPase subunit beta-1
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BQ934151.1, BC000006.2,
CD722755.1, BM762099.1, AA514770.1, U16799.1 and BE223067.1.
This sequence is a reference standard in the RefSeqGene project.
On Jul 1, 2004 this sequence version replaced gi:37595556.
Summary: The protein encoded by this gene belongs to the family of
Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily
of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein
responsible for establishing and maintaining the electrochemical
gradients of Na and K ions across the plasma membrane. These
gradients are essential for osmoregulation, for sodium-coupled
transport of a variety of organic and inorganic molecules, and for
electrical excitability of nerve and muscle. This enzyme is
composed of two subunits, a large catalytic subunit (alpha) and a
smaller glycoprotein subunit (beta). The beta subunit regulates,
through assembly of alpha/beta heterodimers, the number of sodium
pumps transported to the plasma membrane. The glycoprotein subunit
of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a
beta 1 subunit. Alternatively spliced transcript variants encoding
different isoforms have been described, but their biological
validity is not known. [provided by RefSeq, Mar 2010].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BX420567.2, BC000006.2 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.