||ORF Nucleotide Sequence (Length: 912bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||sodium/potassium-transporting ATPase subunit beta-1
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BQ934151.1, BC000006.2,
CD722755.1, BM762099.1, AA514770.1, U16799.1 and BE223067.1.
This sequence is a reference standard in the RefSeqGene project.
On Jul 1, 2004 this sequence version replaced gi:37595556.
Summary: The protein encoded by this gene belongs to the family of
Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily
of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein
responsible for establishing and maintaining the electrochemical
gradients of Na and K ions across the plasma membrane. These
gradients are essential for osmoregulation, for sodium-coupled
transport of a variety of organic and inorganic molecules, and for
electrical excitability of nerve and muscle. This enzyme is
composed of two subunits, a large catalytic subunit (alpha) and a
smaller glycoprotein subunit (beta). The beta subunit regulates,
through assembly of alpha/beta heterodimers, the number of sodium
pumps transported to the plasma membrane. The glycoprotein subunit
of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a
beta 1 subunit. Alternatively spliced transcript variants encoding
different isoforms have been described, but their biological
validity is not known. [provided by RefSeq, Mar 2010].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BX420567.2, BC000006.2 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.