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ALDH7A1 aldehyde dehydrogenase 7 family, member A1 [Homo sapiens (human)]

Gene Symbol ALDH7A1
Entrez Gene ID 501
Full Name aldehyde dehydrogenase 7 family, member A1
Synonyms ATQ1, EPD, PDE
General protein information
Preferred Names
alpha-aminoadipic semialdehyde dehydrogenase
Names
alpha-aminoadipic semialdehyde dehydrogenase
antiquitin-1
P6c dehydrogenase
alpha-AASA dehydrogenase
26g turgor protein homolog
betaine aldehyde dehydrogenase
delta1-piperideine-6-carboxylate dehydrogenase
NP_001173.2
NP_001188306.1
NP_001189333.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

5

5q31

Summary The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011]. lac of sum
Disorder MIM:

107323

Disorder Html: Epilepsy, pyridoxine-dependent, 266100 (3)





The following ALDH7A1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ALDH7A1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu56423 XM_011543417 PREDICTED: Homo sapiens aldehyde dehydrogenase 7 family, member A1 (ALDH7A1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $319
OHu22561 NM_001182 Homo sapiens aldehyde dehydrogenase 7 family, member A1 (ALDH7A1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $439
OHu22668 NM_001201377 Homo sapiens aldehyde dehydrogenase 7 family, member A1 (ALDH7A1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$439
OHu22641 NM_001202404 Homo sapiens aldehyde dehydrogenase 7 family, member A1 (ALDH7A1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $439

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu56423
Accession Version XM_011543417.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1215bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product alpha-aminoadipic semialdehyde dehydrogenase isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_034772.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGGGAAAA TCTTAGTGGA AGGTGTGGGT GAAGTTCAGG AGTATGTGGA TATCTGTGAC 
TATGCTGTTG GTTTATCAAG GATGATTGGA GGACCTATCT TGCCTTCTGA AAGATCTGGC
CATGCACTGA TTGAGCAGTG GAATCCCGTA GGCCTGGTTG GAATCATCAC GGCATTCAAT
TTCCCTGTGG CAGTGTATGG TTGGAACAAC GCCATCGCCA TGATCTGTGG AAATGTCTGC
CTCTGGAAAG GAGCTCCAAC CACTTCCCTC ATTAGTGTGG CTGTCACAAA GATAATAGCC
AAGGTTCTGG AGGACAACAA GCTGCCTGGT GCAATTTGTT CCTTGACTTG TGGTGGAGCA
GATATTGGCA CAGCAATGGC CAAAGATGAA CGAGTGAACC TGCTGTCCTT CACTGGGAGC
ACTCAGGTGG GAAAACAGGT GGGCCTGATG GTGCAGGAGA GGTTTGGGAG AAGTCTGTTG
GAACTTGGAG GAAACAATGC CATTATTGCC TTTGAAGATG CAGACCTCAG CTTAGTTGTT
CCATCAGCTC TCTTCGCTGC TGTGGGAACA GCTGGCCAGA GGTGTACCAC TGCGAGGCGA
CTGTTTATAC ATGAAAGCAT CCATGATGAG GTTGTAAACA GACTTAAAAA GGCCTATGCA
CAGATCCGAG TTGGGAACCC ATGGGACCCT AATGTTCTCT ATGGGCCACT CCACACCAAG
CAGGCAGTGA GCATGTTTCT TGGAGCAGTG GAAGAAGCAA AGAAAGAAGG TGGCACAGTG
GTCTATGGGG GCAAGGTTAT GGATCGCCCT GGAAATTATG TAGAACCGAC AATTGTGACA
GGTCTTGGCC ACGATGCGTC CATTGCACAC ACAGAGACTT TTGCTCCGAT TCTCTATGTC
TTTAAATTCA AGAATGAAGA AGAGGTCTTT GCATGGAATA ATGAAGTAAA ACAGGGACTT
TCAAGTAGCA TCTTTACCAA AGATCTGGGC AGAATCTTTC GCTGGCTTGG ACCTAAAGGA
TCAGACTGTG GCATTGTAAA TGTCAACATT CCAACAAGTG GGGCTGAGAT TGGAGGTGCC
TTTGGAGGAG AAAAGCACAC TGGTGGTGGC AGGGAGTCTG GCAGTGATGC CTGGAAACAG
TACATGAGAA GGTCTACTTG TACTATCAAC TACAGTAAAG ACCTTCCTCT GGCCCAAGGA
ATCAAGTTTC AGTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011541719.1
CDS589..1803
Misc Feature(1)589..1764(+)
Misc Feature(2)664..1761(+)
Misc Feature(3)757..1671(+)
Misc Feature(4)766..1173(+)
Translation
Position Chain Variation Link
1 1 -, a dbSNP:747955382
26 26 g, t dbSNP:370117983
80 80 a, g dbSNP:769304863
87 87 c, g dbSNP:530335400
100 100 c, g dbSNP:532080347
155 155 -, tcct dbSNP:761390661
178 178 a, c dbSNP:182060818
193 193 a, g dbSNP:756840658
195 195 a, c dbSNP:139882553
196 196 a, g dbSNP:755617413
201 201 a, g dbSNP:746488748
224 224 a, g dbSNP:150681998
225 225 a, t dbSNP:190192547
237 237 a, g dbSNP:774494695
278 278 a, c dbSNP:559141820
280 280 c, t dbSNP:765078104
285 285 a, g dbSNP:755286176
288 288 a, g dbSNP:541123495
290 290 c, g dbSNP:768611199
292 292 a, g dbSNP:754158640
296 296 c, t dbSNP:145704075
298 298 a, g dbSNP:756920000
306 306 c, g dbSNP:760863665
316 316 c, t dbSNP:561586729
320 320 a, g dbSNP:768070528
322 322 a, g dbSNP:572479930
325 325 a, g dbSNP:10519915
326 326 c, t dbSNP:763946523
332 332 a, g dbSNP:140292354
336 336 c, t dbSNP:778966998
339 339 c, t dbSNP:754864309
340 340 a, g dbSNP:753558719
343 343 c, t dbSNP:780386633
347 347 a, c dbSNP:756220906
348 348 c, t dbSNP:750527809
351 351 a, t dbSNP:767444977
352 352 c, t dbSNP:762338356
353 353 g, t dbSNP:752100211
356 356 c, t dbSNP:199762757
361 361 c, t dbSNP:372073658
362 362 a, c dbSNP:775652360
364 364 g, t dbSNP:770632526
367 367 g, t dbSNP:760199317
383 383 a, c, t dbSNP:543181020
384 384 a, g, t dbSNP:747643987
386 386 a, c dbSNP:58528748
390 390 c, t dbSNP:369516597
391 391 c, t dbSNP:768706976
406 406 a, g dbSNP:749111036
409 409 c, t dbSNP:779654060
412 412 a, c dbSNP:756379659
415 415 a, g dbSNP:750569691
418 418 a, g dbSNP:794727259
419 419 c, g dbSNP:781361567
424 424 c, t dbSNP:757377110
426 426 a, g dbSNP:146438406
429 429 a, g dbSNP:755397405
433 433 a, c dbSNP:775388343
434 434 a, g dbSNP:769518060
438 438 a, g dbSNP:745653970
445 445 c, t dbSNP:368517032
446 446 a, t dbSNP:376294954
448 448 c, g dbSNP:747103219
456 456 c, t dbSNP:60720055
459 459 a, g dbSNP:758973869
466 466 a, g dbSNP:551163406
468 468 -, g dbSNP:758414053
468 468 a, c dbSNP:754969438
470 470 g, t dbSNP:765748549
477 477 a, t dbSNP:755352873
511 511 c, g, t dbSNP:121912708
514 514 g, t dbSNP:763780569
528 528 a, g dbSNP:762428797
533 533 c, t dbSNP:749853326
537 537 c, t dbSNP:149228266
539 539 a, g dbSNP:765099324
541 541 c, g dbSNP:759418993
542 542 a, c, g, t dbSNP:549279821
545 545 c, t dbSNP:145329188
547 547 c, t dbSNP:370624118
556 556 a, g dbSNP:117295656
569 569 a, g dbSNP:778997049
577 577 a, g dbSNP:760527001
598 598 a, c dbSNP:772989605
600 600 c, t dbSNP:772201739
606 606 c, g dbSNP:199653162
612 612 g, t dbSNP:774328460
615 615 a, g dbSNP:768899130
618 618 g, t dbSNP:749358074
625 625 c, g, t dbSNP:551773096
633 633 c, t dbSNP:375095250
668 668 a, g dbSNP:781569684
669 669 g, t dbSNP:758016489
674 674 c, t dbSNP:747873042
677 677 c, g dbSNP:375491094
678 678 a, g dbSNP:754537923
685 685 a, g dbSNP:753339039
702 702 a, t dbSNP:200447936
705 705 g, t dbSNP:756081030
708 708 c, t dbSNP:750418342
710 710 a, g dbSNP:767336581
711 711 c, t dbSNP:757135576
712 712 c, g dbSNP:140102105
713 713 a, c dbSNP:764417585
715 715 -, ctgattgagca dbSNP:765119568
719 719 c, t dbSNP:763217060
721 721 a, g dbSNP:775743077
733 733 c, g dbSNP:765445537
735 735 c, t dbSNP:369859575
736 736 a, g, t dbSNP:61757685
742 742 c, t dbSNP:771335275
758 758 c, t dbSNP:376917645
760 760 a, g dbSNP:773503933
767 767 a, g dbSNP:372660425
771 771 c, t dbSNP:748904145
772 772 c, t dbSNP:779652673
775 775 a, g dbSNP:769398736
779 779 c, t dbSNP:121912709
780 780 a, g dbSNP:745357569
785 785 a, g dbSNP:781259686
790 790 g, t dbSNP:555896752
798 798 c, t dbSNP:369380330
802 802 a, g dbSNP:777670051
804 804 c, t dbSNP:758236544
805 805 a, g dbSNP:753014428
806 806 c, t dbSNP:200433565
810 810 a, g dbSNP:765542228
813 813 c, g dbSNP:759724393
822 822 c, t dbSNP:537260194
829 829 c, t dbSNP:753791407
839 839 c, g dbSNP:202084501
847 847 a, g dbSNP:777829351
848 848 c, t dbSNP:140827978
849 849 c, t dbSNP:758324700
856 856 c, t dbSNP:752533662
858 858 c, t dbSNP:57902950
862 862 a, g dbSNP:755093525
865 865 a, g dbSNP:201832111
871 871 a, g dbSNP:752824129
882 882 a, t dbSNP:756247675
889 889 a, g dbSNP:750500704
900 900 a, g dbSNP:768018240
903 903 c, t dbSNP:757704473
904 904 a, c dbSNP:751944211
913 913 a, c dbSNP:140701322
931 931 a, t dbSNP:763353456
953 953 c, t dbSNP:776202861
963 963 a, g dbSNP:772877760
964 964 a, g dbSNP:767172222
985 985 a, t dbSNP:761387197
990 990 a, g dbSNP:774216010
1007 1007 a, g dbSNP:768638552
1012 1012 c, g dbSNP:369271104
1015 1015 -, g dbSNP:746295168
1017 1017 a, c, g, t dbSNP:201948406
1022 1022 a, g dbSNP:746052220
1025 1025 a, g dbSNP:781369461
1026 1026 c, g dbSNP:771054683
1035 1035 c, g dbSNP:747107627
1036 1036 a, g dbSNP:778146305
1041 1041 a, g dbSNP:150623275
1058 1058 g, t dbSNP:756879600
1065 1065 c, g dbSNP:751053781
1067 1067 g, t dbSNP:763620908
1082 1082 a, c dbSNP:762340782
1085 1085 a, t dbSNP:121912711
1090 1090 a, g dbSNP:765153843
1097 1097 c, g dbSNP:141775154
1106 1106 a, g dbSNP:767632811
1113 1113 c, t dbSNP:202069068
1123 1123 c, g dbSNP:774519989
1130 1130 -, c dbSNP:778003597
1130 1130 c, t dbSNP:572990686
1133 1133 c, t dbSNP:148052962
1138 1138 c, g dbSNP:775830338
1143 1143 c, t dbSNP:114516357
1144 1144 a, g dbSNP:746212816
1145 1145 c, t dbSNP:3189320
1148 1148 c, t dbSNP:777483675
1170 1170 a, g dbSNP:761295869
1178 1178 c, g dbSNP:543182575
1181 1181 c, t dbSNP:144625212
1182 1182 a, g dbSNP:563675719
1183 1183 a, g dbSNP:111319259
1187 1187 a, g dbSNP:754449549
1193 1193 g, t dbSNP:747834606
1195 1195 a, g dbSNP:374248561
1198 1198 c, t dbSNP:768210262
1199 1199 a, g dbSNP:199767457
1200 1200 c, t dbSNP:200394848
1205 1205 a, g dbSNP:141701364
1206 1206 c, t dbSNP:750258751
1219 1219 a, g dbSNP:780813341
1222 1222 a, g dbSNP:757087792
1226 1226 a, g dbSNP:751879860
1229 1229 c, g dbSNP:553114356
1234 1234 a, g dbSNP:763193538
1242 1242 c, t dbSNP:752660981
1246 1246 a, g dbSNP:765795361
1248 1248 a, g dbSNP:759921213
1249 1249 c, g dbSNP:138675705
1251 1251 a, g dbSNP:376004978
1252 1252 a, g dbSNP:761011399
1253 1253 c, t dbSNP:774055048
1255 1255 c, t dbSNP:768233031
1256 1256 g, t dbSNP:144671885
1259 1259 c, t dbSNP:201752552
1263 1263 a, g dbSNP:779387233
1267 1267 c, t dbSNP:532800318
1268 1268 c, t dbSNP:745833299
1271 1271 a, g dbSNP:781254582
1276 1276 c, t dbSNP:370869432
1296 1296 a, g dbSNP:755077088
1309 1309 a, c, t dbSNP:564187364
1312 1312 a, g dbSNP:750205677
1316 1316 c, t dbSNP:7447092
1333 1333 a, g dbSNP:140947675
1339 1339 a, g dbSNP:756568507
1343 1343 a, c dbSNP:750821093
1350 1350 a, g dbSNP:767913793
1353 1353 a, g dbSNP:544253617
1366 1366 a, g dbSNP:373304485
1369 1369 a, g dbSNP:764939934
1373 1373 a, t dbSNP:758974665
1393 1393 c, t dbSNP:181287032
1394 1394 a, g dbSNP:771975420
1395 1395 c, t dbSNP:761523599
1400 1400 c, g dbSNP:774148433
1407 1407 c, g, t dbSNP:121912710
1415 1415 c, t dbSNP:780233639
1416 1416 a, g dbSNP:572831296
1417 1417 a, g dbSNP:2306618
1420 1420 a, g dbSNP:201792544
1426 1426 a, t dbSNP:757726867
1427 1427 c, g dbSNP:751898560
1440 1440 c, t dbSNP:778236831
1441 1441 a, g dbSNP:758810390
1445 1445 c, t dbSNP:753598402
1446 1446 a, g dbSNP:587780850
1450 1450 a, g dbSNP:760266177
1455 1455 a, g dbSNP:749889093
1458 1458 c, t dbSNP:767375552
1459 1459 a, g dbSNP:150305320
1460 1460 c, t dbSNP:774126237
1462 1462 c, g dbSNP:121912707
1467 1467 a, t dbSNP:762723665
1469 1469 c, t dbSNP:775759943
1470 1470 c, t dbSNP:375030056
1475 1475 c, t dbSNP:151107837
1476 1476 a, g dbSNP:538504116
1479 1479 g, t dbSNP:372127110
1480 1480 c, t dbSNP:548996847
1484 1484 -, at dbSNP:753671880
1484 1484 a, g dbSNP:747597620
1486 1486 a, g dbSNP:778125731
1488 1488 c, g dbSNP:142975776
1498 1498 a, c dbSNP:12514417
1503 1503 c, t dbSNP:755365818
1512 1512 a, g dbSNP:745584430
1518 1518 c, t dbSNP:780696540
1532 1532 a, g dbSNP:200299784
1533 1533 a, g dbSNP:200980969
1539 1539 a, c dbSNP:756859037
1543 1543 g, t dbSNP:750971835
1552 1552 a, c dbSNP:764036426
1558 1558 a, g, t dbSNP:186558364
1567 1567 a, g dbSNP:375090702
1579 1579 a, g dbSNP:113609617
1588 1588 c, t dbSNP:752523070
1589 1589 a, g dbSNP:147940248
1590 1590 c, g dbSNP:759234889
1594 1594 -, g dbSNP:772766995
1617 1617 -, tg dbSNP:770492145
1625 1625 c, t dbSNP:144701796
1640 1640 c, t dbSNP:766645306
1642 1642 -, a dbSNP:760092559
1643 1643 -, caa dbSNP:777187854
1644 1644 a, g dbSNP:372488916
1647 1647 c, t dbSNP:750640713
1660 1660 g, t dbSNP:767756650
1664 1664 g, t dbSNP:763418390
1669 1669 c, t dbSNP:202104680
1673 1673 g, t dbSNP:751635252
1674 1674 a, g dbSNP:764688935
1689 1689 c, t dbSNP:565405031
1696 1696 c, g dbSNP:556400964
1698 1698 c, t dbSNP:765576421
1703 1703 a, c, g dbSNP:80049945
1704 1704 a, g dbSNP:540451615
1717 1717 a, g dbSNP:771651423
1730 1730 a, g dbSNP:200102503
1733 1733 c, t dbSNP:773694788
1736 1736 a, c, g dbSNP:749231711
1739 1739 a, g dbSNP:561343926
1744 1744 a, g dbSNP:755930241
1747 1747 a, t dbSNP:745592760
1750 1750 a, g dbSNP:61757684
1753 1753 a, g dbSNP:765681480
1755 1755 a, c dbSNP:556737742
1757 1757 a, g dbSNP:754312564
1761 1761 c, t dbSNP:538884744
1762 1762 a, g dbSNP:761013423
1780 1780 a, g dbSNP:749839120
1780 1780 -, g dbSNP:387906574
1791 1791 c, g dbSNP:763737676
1792 1792 a, g dbSNP:762383899
1793 1793 a, g dbSNP:775017806
1800 1800 a, g dbSNP:769887865
1808 1808 a, g dbSNP:759591318
1809 1809 g, t dbSNP:776690396
1832 1832 c, t dbSNP:559710313
1836 1836 a, g dbSNP:374780587
1845 1845 c, g dbSNP:371971136
1849 1849 g, t dbSNP:372788241
1850 1850 g, t dbSNP:777869197
1868 1868 -, gaaa dbSNP:765576367
1871 1871 a, g dbSNP:2775
1902 1902 g, t dbSNP:553327175
1943 1943 c, g dbSNP:374361465
1952 1952 a, g dbSNP:187827993
2003 2003 a, g dbSNP:549472131
2015 2015 a, c dbSNP:143317618

Target ORF information:

RefSeq Version XM_011543417
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens aldehyde dehydrogenase 7 family, member A1 (ALDH7A1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011543417

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGGGAAAA TCTTAGTGGA AGGTGTGGGT GAAGTTCAGG AGTATGTGGA TATCTGTGAC 
TATGCTGTTG GTTTATCAAG GATGATTGGA GGACCTATCT TGCCTTCTGA AAGATCTGGC
CATGCACTGA TTGAGCAGTG GAATCCCGTA GGCCTGGTTG GAATCATCAC GGCATTCAAT
TTCCCTGTGG CAGTGTATGG TTGGAACAAC GCCATCGCCA TGATCTGTGG AAATGTCTGC
CTCTGGAAAG GAGCTCCAAC CACTTCCCTC ATTAGTGTGG CTGTCACAAA GATAATAGCC
AAGGTTCTGG AGGACAACAA GCTGCCTGGT GCAATTTGTT CCTTGACTTG TGGTGGAGCA
GATATTGGCA CAGCAATGGC CAAAGATGAA CGAGTGAACC TGCTGTCCTT CACTGGGAGC
ACTCAGGTGG GAAAACAGGT GGGCCTGATG GTGCAGGAGA GGTTTGGGAG AAGTCTGTTG
GAACTTGGAG GAAACAATGC CATTATTGCC TTTGAAGATG CAGACCTCAG CTTAGTTGTT
CCATCAGCTC TCTTCGCTGC TGTGGGAACA GCTGGCCAGA GGTGTACCAC TGCGAGGCGA
CTGTTTATAC ATGAAAGCAT CCATGATGAG GTTGTAAACA GACTTAAAAA GGCCTATGCA
CAGATCCGAG TTGGGAACCC ATGGGACCCT AATGTTCTCT ATGGGCCACT CCACACCAAG
CAGGCAGTGA GCATGTTTCT TGGAGCAGTG GAAGAAGCAA AGAAAGAAGG TGGCACAGTG
GTCTATGGGG GCAAGGTTAT GGATCGCCCT GGAAATTATG TAGAACCGAC AATTGTGACA
GGTCTTGGCC ACGATGCGTC CATTGCACAC ACAGAGACTT TTGCTCCGAT TCTCTATGTC
TTTAAATTCA AGAATGAAGA AGAGGTCTTT GCATGGAATA ATGAAGTAAA ACAGGGACTT
TCAAGTAGCA TCTTTACCAA AGATCTGGGC AGAATCTTTC GCTGGCTTGG ACCTAAAGGA
TCAGACTGTG GCATTGTAAA TGTCAACATT CCAACAAGTG GGGCTGAGAT TGGAGGTGCC
TTTGGAGGAG AAAAGCACAC TGGTGGTGGC AGGGAGTCTG GCAGTGATGC CTGGAAACAG
TACATGAGAA GGTCTACTTG TACTATCAAC TACAGTAAAG ACCTTCCTCT GGCCCAAGGA
ATCAAGTTTC AGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22561
Accession Version NM_001182.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1620bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product alpha-aminoadipic semialdehyde dehydrogenase isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC375277.1, BC071712.1, AK021800.1, AC093535.2, DB501575.1, BU153725.1, CD678674.1, BG680326.1, AK123774.1 and AI039375.1. This sequence is a reference standard in the RefSeqGene project. On Jan 19, 2011 this sequence version replaced gi:188035923. Summary: The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011]. Transcript Variant: This variant (1) encodes two isoforms resulting from the use of alternative in-frame translation initiation codons. The longer isoform (1) is derived from an upstream AUG (at nt 193-195), while the shorter isoform (2) is derived from a downstream AUG (at nt 277-279). This RefSeq represents the longer isoform, which resides in the mitochondria (PMIDs: 20207735 and 19885858). Sequence Note: This Refseq, containing three potential in-frame translation initiation codons (all with weak Kozak signals), is annotated with a CDS starting from a downstream start codon (at nt 193-195) based on better conservation, N-terminal consistency with homologous proteins, and the presence of a transit peptide, which is essential for the localization of this isoform in the mitochondria (PMIDs: 20207735 and 19885858), and is consistent with the function of this gene in lysine catabolism (which is known to occur in the mitochondria). The use of an upstream start codon (at nt 112-114) that is present in only a subset of higher mammals, would increase the protein length by 27 aa. A shorter, soluble isoform resulting from the use of another downstream start codon (at nt 277-279) is represented in a separate RefSeq (NM_001201377.1). This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal (PMID:19885858) gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: BC071712.1, S74728.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGTGGCGCC TTCCTCGCGC GCTGTGTGTG CACGCTGCAA AGACCAGCAA GCTCTCTGGA 
CCTTGGAGCA GGCCTGCCGC CTTCATGTCC ACTCTCCTCA TCAATCAGCC CCAGTATGCG
TGGCTGAAAG AGCTGGGGCT CCGCGAGGAA AACGAGGGCG TGTATAATGG AAGCTGGGGA
GGCCGGGGAG AGGTTATTAC GACCTATTGC CCTGCTAACA ACGAGCCAAT AGCAAGAGTC
CGACAGGCCA GTGTGGCAGA CTATGAAGAA ACTGTAAAGA AAGCAAGAGA AGCATGGAAA
ATCTGGGCAG ATATTCCTGC TCCAAAACGA GGAGAAATAG TAAGACAGAT TGGCGATGCC
TTGCGGGAGA AGATCCAAGT ACTAGGAAGC TTGGTGTCTT TGGAGATGGG GAAAATCTTA
GTGGAAGGTG TGGGTGAAGT TCAGGAGTAT GTGGATATCT GTGACTATGC TGTTGGTTTA
TCAAGGATGA TTGGAGGACC TATCTTGCCT TCTGAAAGAT CTGGCCATGC ACTGATTGAG
CAGTGGAATC CCGTAGGCCT GGTTGGAATC ATCACGGCAT TCAATTTCCC TGTGGCAGTG
TATGGTTGGA ACAACGCCAT CGCCATGATC TGTGGAAATG TCTGCCTCTG GAAAGGAGCT
CCAACCACTT CCCTCATTAG TGTGGCTGTC ACAAAGATAA TAGCCAAGGT TCTGGAGGAC
AACAAGCTGC CTGGTGCAAT TTGTTCCTTG ACTTGTGGTG GAGCAGATAT TGGCACAGCA
ATGGCCAAAG ATGAACGAGT GAACCTGCTG TCCTTCACTG GGAGCACTCA GGTGGGAAAA
CAGGTGGGCC TGATGGTGCA GGAGAGGTTT GGGAGAAGTC TGTTGGAACT TGGAGGAAAC
AATGCCATTA TTGCCTTTGA AGATGCAGAC CTCAGCTTAG TTGTTCCATC AGCTCTCTTC
GCTGCTGTGG GAACAGCTGG CCAGAGGTGT ACCACTGCGA GGCGACTGTT TATACATGAA
AGCATCCATG ATGAGGTTGT AAACAGACTT AAAAAGGCCT ATGCACAGAT CCGAGTTGGG
AACCCATGGG ACCCTAATGT TCTCTATGGG CCACTCCACA CCAAGCAGGC AGTGAGCATG
TTTCTTGGAG CAGTGGAAGA AGCAAAGAAA GAAGGTGGCA CAGTGGTCTA TGGGGGCAAG
GTTATGGATC GCCCTGGAAA TTATGTAGAA CCGACAATTG TGACAGGTCT TGGCCACGAT
GCGTCCATTG CACACACAGA GACTTTTGCT CCGATTCTCT ATGTCTTTAA ATTCAAGAAT
GAAGAAGAGG TCTTTGCATG GAATAATGAA GTAAAACAGG GACTTTCAAG TAGCATCTTT
ACCAAAGATC TGGGCAGAAT CTTTCGCTGG CTTGGACCTA AAGGATCAGA CTGTGGCATT
GTAAATGTCA ACATTCCAAC AAGTGGGGCT GAGATTGGAG GTGCCTTTGG AGGAGAAAAG
CACACTGGTG GTGGCAGGGA GTCTGGCAGT GATGCCTGGA AACAGTACAT GAGAAGGTCT
ACTTGTACTA TCAACTACAG TAAAGACCTT CCTCTGGCCC AAGGAATCAA GTTTCAGTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001173.2
CDS193..1812
Misc Feature(1)112..114(+)
Misc Feature(2)349..1773(+)
Misc Feature(3)490..1770(+)
Misc Feature(4)766..1680(+)
Misc Feature(5)775..1182(+)
Misc Feature(6)775..777(+)
Misc Feature(7)277..279(+)
Exon (1)1..384
Gene:ALDH7A1
Gene Synonym:
Exon (2)385..438
Gene:ALDH7A1
Gene Synonym:
Exon (3)439..504
Gene:ALDH7A1
Gene Synonym:
Exon (4)505..585
Gene:ALDH7A1
Gene Synonym:
Exon (5)586..709
Gene:ALDH7A1
Gene Synonym:
Exon (6)710..842
Gene:ALDH7A1
Gene Synonym:
Exon (7)843..887
Gene:ALDH7A1
Gene Synonym:
Exon (8)888..965
Gene:ALDH7A1
Gene Synonym:
Exon (9)966..1063
Gene:ALDH7A1
Gene Synonym:
Exon (10)1064..1105
Gene:ALDH7A1
Gene Synonym:
Exon (11)1106..1200
Gene:ALDH7A1
Gene Synonym:
Exon (12)1201..1285
Gene:ALDH7A1
Gene Synonym:
Exon (13)1286..1392
Gene:ALDH7A1
Gene Synonym:
Exon (14)1393..1509
Gene:ALDH7A1
Gene Synonym:
Exon (15)1510..1607
Gene:ALDH7A1
Gene Synonym:
Exon (16)1608..1681
Gene:ALDH7A1
Gene Synonym:
Exon (17)1682..1757
Gene:ALDH7A1
Gene Synonym:
Exon (18)1758..4936
Gene:ALDH7A1
Gene Synonym:
Translation
Position Chain Variation Link
35 35 g, t dbSNP:563329202
42 42 c, t dbSNP:900640
55 55 a, t dbSNP:577761503
61 61 a, c dbSNP:900641
64 64 a, c dbSNP:532564619
65 65 c, g dbSNP:768908360
75 75 a, c dbSNP:752916959
76 76 g, t dbSNP:146562077
93 93 a, g dbSNP:780114646
113 113 g, t dbSNP:563928852
123 123 c, t dbSNP:746337997
124 124 a, g dbSNP:573822035
129 129 a, g dbSNP:757747897
132 132 g, t dbSNP:751940730
133 133 a, g dbSNP:144272515
138 138 -, gctctatttcagc dbSNP:756450524
139 139 c, t dbSNP:537006969
159 159 c, g, t dbSNP:140627539
162 162 a, c dbSNP:765830909
163 163 c, t dbSNP:760633380
164 164 c, t dbSNP:556650006
165 165 c, t dbSNP:767418609
170 170 g, t dbSNP:761568340
180 180 g, t dbSNP:774190967
186 186 g, t dbSNP:768763698
190 190 a, c dbSNP:763177883
191 191 a, g dbSNP:763823758
200 200 a, g dbSNP:759866910
201 201 c, t dbSNP:770033340
205 205 c, t dbSNP:745921838
208 208 c, t dbSNP:781779462
210 210 c, t dbSNP:771562794
217 217 c, t dbSNP:747342957
223 223 c, g dbSNP:778144937
224 224 a, t dbSNP:754614105
225 225 c, g dbSNP:753485531
226 226 -, g dbSNP:750693623
228 228 c, t dbSNP:779646478
230 230 c, g dbSNP:367820135
231 231 a, g dbSNP:201566142
235 235 a, t dbSNP:1049211
238 238 -, acca dbSNP:767805540
247 247 c, t dbSNP:749919953
248 248 c, g dbSNP:566243475
252 252 a, t dbSNP:1049214
255 255 c, t dbSNP:368427726
258 258 c, g dbSNP:1049217
261 261 c, t dbSNP:763900156
265 265 c, t dbSNP:762624752
270 270 c, t dbSNP:11542969
274 274 c, t dbSNP:775904572
277 277 a, g dbSNP:765544488
284 284 c, t dbSNP:759758133
285 285 g, t dbSNP:776788391
287 287 a, t dbSNP:375009404
289 289 c, t dbSNP:771357813
292 292 -, a dbSNP:761986050
292 292 a, g dbSNP:747505504
294 294 c, g dbSNP:773484446
296 296 a, g dbSNP:547648880
300 300 c, g, t dbSNP:779736481
303 303 c, t dbSNP:372328305
309 309 g, t dbSNP:755756776
311 311 c, t dbSNP:745385277
325 325 a, c, t dbSNP:757162735
327 327 a, g dbSNP:751474057
330 330 a, g dbSNP:770975428
331 331 c, t dbSNP:144684547
333 333 a, c dbSNP:763915613
342 342 a, t dbSNP:758272364
345 345 c, t dbSNP:752537865
346 346 c, g dbSNP:765562932
375 375 a, c dbSNP:374526203
378 378 a, g dbSNP:776876925
379 379 a, g, t dbSNP:760636660
392 392 a, c, t dbSNP:543181020
393 393 a, g, t dbSNP:747643987
395 395 a, c dbSNP:58528748
399 399 c, t dbSNP:369516597
400 400 c, t dbSNP:768706976
415 415 a, g dbSNP:749111036
418 418 c, t dbSNP:779654060
421 421 a, c dbSNP:756379659
424 424 a, g dbSNP:750569691
427 427 a, g dbSNP:794727259
428 428 c, g dbSNP:781361567
433 433 c, t dbSNP:757377110
435 435 a, g dbSNP:146438406
438 438 a, g dbSNP:755397405
442 442 a, c dbSNP:775388343
443 443 a, g dbSNP:769518060
447 447 a, g dbSNP:745653970
454 454 c, t dbSNP:368517032
455 455 a, t dbSNP:376294954
457 457 c, g dbSNP:747103219
465 465 c, t dbSNP:60720055
468 468 a, g dbSNP:758973869
475 475 a, g dbSNP:551163406
477 477 -, g dbSNP:758414053
477 477 a, c dbSNP:754969438
479 479 g, t dbSNP:765748549
486 486 a, t dbSNP:755352873
520 520 c, g, t dbSNP:121912708
523 523 g, t dbSNP:763780569
537 537 a, g dbSNP:762428797
542 542 c, t dbSNP:749853326
546 546 c, t dbSNP:149228266
548 548 a, g dbSNP:765099324
550 550 c, g dbSNP:759418993
551 551 a, c, g, t dbSNP:549279821
554 554 c, t dbSNP:145329188
556 556 c, t dbSNP:370624118
565 565 a, g dbSNP:117295656
578 578 a, g dbSNP:778997049
586 586 a, g dbSNP:760527001
607 607 a, c dbSNP:772989605
609 609 c, t dbSNP:772201739
615 615 c, g dbSNP:199653162
621 621 g, t dbSNP:774328460
624 624 a, g dbSNP:768899130
627 627 g, t dbSNP:749358074
634 634 c, g, t dbSNP:551773096
642 642 c, t dbSNP:375095250
677 677 a, g dbSNP:781569684
678 678 g, t dbSNP:758016489
683 683 c, t dbSNP:747873042
686 686 c, g dbSNP:375491094
687 687 a, g dbSNP:754537923
694 694 a, g dbSNP:753339039
711 711 a, t dbSNP:200447936
714 714 g, t dbSNP:756081030
717 717 c, t dbSNP:750418342
719 719 a, g dbSNP:767336581
720 720 c, t dbSNP:757135576
721 721 c, g dbSNP:140102105
722 722 a, c dbSNP:764417585
724 724 -, ctgattgagca dbSNP:765119568
728 728 c, t dbSNP:763217060
730 730 a, g dbSNP:775743077
742 742 c, g dbSNP:765445537
744 744 c, t dbSNP:369859575
745 745 a, g, t dbSNP:61757685
751 751 c, t dbSNP:771335275
767 767 c, t dbSNP:376917645
769 769 a, g dbSNP:773503933
776 776 a, g dbSNP:372660425
780 780 c, t dbSNP:748904145
781 781 c, t dbSNP:779652673
784 784 a, g dbSNP:769398736
788 788 c, t dbSNP:121912709
789 789 a, g dbSNP:745357569
794 794 a, g dbSNP:781259686
799 799 g, t dbSNP:555896752
807 807 c, t dbSNP:369380330
811 811 a, g dbSNP:777670051
813 813 c, t dbSNP:758236544
814 814 a, g dbSNP:753014428
815 815 c, t dbSNP:200433565
819 819 a, g dbSNP:765542228
822 822 c, g dbSNP:759724393
831 831 c, t dbSNP:537260194
838 838 c, t dbSNP:753791407
848 848 c, g dbSNP:202084501
856 856 a, g dbSNP:777829351
857 857 c, t dbSNP:140827978
858 858 c, t dbSNP:758324700
865 865 c, t dbSNP:752533662
867 867 c, t dbSNP:57902950
871 871 a, g dbSNP:755093525
874 874 a, g dbSNP:201832111
880 880 a, g dbSNP:752824129
891 891 a, t dbSNP:756247675
898 898 a, g dbSNP:750500704
909 909 a, g dbSNP:768018240
912 912 c, t dbSNP:757704473
913 913 a, c dbSNP:751944211
922 922 a, c dbSNP:140701322
940 940 a, t dbSNP:763353456
962 962 c, t dbSNP:776202861
972 972 a, g dbSNP:772877760
973 973 a, g dbSNP:767172222
994 994 a, t dbSNP:761387197
999 999 a, g dbSNP:774216010
1016 1016 a, g dbSNP:768638552
1021 1021 c, g dbSNP:369271104
1024 1024 -, g dbSNP:746295168
1026 1026 a, c, g, t dbSNP:201948406
1031 1031 a, g dbSNP:746052220
1034 1034 a, g dbSNP:781369461
1035 1035 c, g dbSNP:771054683
1044 1044 c, g dbSNP:747107627
1045 1045 a, g dbSNP:778146305
1050 1050 a, g dbSNP:150623275
1067 1067 g, t dbSNP:756879600
1074 1074 c, g dbSNP:751053781
1076 1076 g, t dbSNP:763620908
1091 1091 a, c dbSNP:762340782
1094 1094 a, t dbSNP:121912711
1099 1099 a, g dbSNP:765153843
1106 1106 c, g dbSNP:141775154
1115 1115 a, g dbSNP:767632811
1122 1122 c, t dbSNP:202069068
1132 1132 c, g dbSNP:774519989
1139 1139 -, c dbSNP:778003597
1139 1139 c, t dbSNP:572990686
1142 1142 c, t dbSNP:148052962
1147 1147 c, g dbSNP:775830338
1152 1152 c, t dbSNP:114516357
1153 1153 a, g dbSNP:746212816
1154 1154 c, t dbSNP:3189320
1157 1157 c, t dbSNP:777483675
1179 1179 a, g dbSNP:761295869
1187 1187 c, g dbSNP:543182575
1190 1190 c, t dbSNP:144625212
1191 1191 a, g dbSNP:563675719
1192 1192 a, g dbSNP:111319259
1196 1196 a, g dbSNP:754449549
1202 1202 g, t dbSNP:747834606
1204 1204 a, g dbSNP:374248561
1207 1207 c, t dbSNP:768210262
1208 1208 a, g dbSNP:199767457
1209 1209 c, t dbSNP:200394848
1214 1214 a, g dbSNP:141701364
1215 1215 c, t dbSNP:750258751
1228 1228 a, g dbSNP:780813341
1231 1231 a, g dbSNP:757087792
1235 1235 a, g dbSNP:751879860
1238 1238 c, g dbSNP:553114356
1243 1243 a, g dbSNP:763193538
1251 1251 c, t dbSNP:752660981
1255 1255 a, g dbSNP:765795361
1257 1257 a, g dbSNP:759921213
1258 1258 c, g dbSNP:138675705
1260 1260 a, g dbSNP:376004978
1261 1261 a, g dbSNP:761011399
1262 1262 c, t dbSNP:774055048
1264 1264 c, t dbSNP:768233031
1265 1265 g, t dbSNP:144671885
1268 1268 c, t dbSNP:201752552
1272 1272 a, g dbSNP:779387233
1276 1276 c, t dbSNP:532800318
1277 1277 c, t dbSNP:745833299
1280 1280 a, g dbSNP:781254582
1285 1285 c, t dbSNP:370869432
1305 1305 a, g dbSNP:755077088
1318 1318 a, c, t dbSNP:564187364
1321 1321 a, g dbSNP:750205677
1325 1325 c, t dbSNP:7447092
1342 1342 a, g dbSNP:140947675
1348 1348 a, g dbSNP:756568507
1352 1352 a, c dbSNP:750821093
1359 1359 a, g dbSNP:767913793
1362 1362 a, g dbSNP:544253617
1375 1375 a, g dbSNP:373304485
1378 1378 a, g dbSNP:764939934
1382 1382 a, t dbSNP:758974665
1402 1402 c, t dbSNP:181287032
1403 1403 a, g dbSNP:771975420
1404 1404 c, t dbSNP:761523599
1409 1409 c, g dbSNP:774148433
1416 1416 c, g, t dbSNP:121912710
1424 1424 c, t dbSNP:780233639
1425 1425 a, g dbSNP:572831296
1426 1426 a, g dbSNP:2306618
1429 1429 a, g dbSNP:201792544
1435 1435 a, t dbSNP:757726867
1436 1436 c, g dbSNP:751898560
1449 1449 c, t dbSNP:778236831
1450 1450 a, g dbSNP:758810390
1454 1454 c, t dbSNP:753598402
1455 1455 a, g dbSNP:587780850
1459 1459 a, g dbSNP:760266177
1464 1464 a, g dbSNP:749889093
1467 1467 c, t dbSNP:767375552
1468 1468 a, g dbSNP:150305320
1469 1469 c, t dbSNP:774126237
1471 1471 c, g dbSNP:121912707
1476 1476 a, t dbSNP:762723665
1478 1478 c, t dbSNP:775759943
1479 1479 c, t dbSNP:375030056
1484 1484 c, t dbSNP:151107837
1485 1485 a, g dbSNP:538504116
1488 1488 g, t dbSNP:372127110
1489 1489 c, t dbSNP:548996847
1493 1493 -, at dbSNP:753671880
1493 1493 a, g dbSNP:747597620
1495 1495 a, g dbSNP:778125731
1497 1497 c, g dbSNP:142975776
1507 1507 a, c dbSNP:12514417
1512 1512 c, t dbSNP:755365818
1521 1521 a, g dbSNP:745584430
1527 1527 c, t dbSNP:780696540
1541 1541 a, g dbSNP:200299784
1542 1542 a, g dbSNP:200980969
1548 1548 a, c dbSNP:756859037
1552 1552 g, t dbSNP:750971835
1561 1561 a, c dbSNP:764036426
1567 1567 a, g, t dbSNP:186558364
1576 1576 a, g dbSNP:375090702
1588 1588 a, g dbSNP:113609617
1597 1597 c, t dbSNP:752523070
1598 1598 a, g dbSNP:147940248
1599 1599 c, g dbSNP:759234889
1603 1603 -, g dbSNP:772766995
1626 1626 -, tg dbSNP:770492145
1634 1634 c, t dbSNP:144701796
1649 1649 c, t dbSNP:766645306
1651 1651 -, a dbSNP:760092559
1652 1652 -, caa dbSNP:777187854
1653 1653 a, g dbSNP:372488916
1656 1656 c, t dbSNP:750640713
1669 1669 g, t dbSNP:767756650
1673 1673 g, t dbSNP:763418390
1678 1678 c, t dbSNP:202104680
1682 1682 g, t dbSNP:751635252
1683 1683 a, g dbSNP:764688935
1698 1698 c, t dbSNP:565405031
1705 1705 c, g dbSNP:556400964
1707 1707 c, t dbSNP:765576421
1712 1712 a, c, g dbSNP:80049945
1713 1713 a, g dbSNP:540451615
1726 1726 a, g dbSNP:771651423
1739 1739 a, g dbSNP:200102503
1742 1742 c, t dbSNP:773694788
1745 1745 a, c, g dbSNP:749231711
1748 1748 a, g dbSNP:561343926
1753 1753 a, g dbSNP:755930241
1756 1756 a, t dbSNP:745592760
1759 1759 a, g dbSNP:61757684
1762 1762 a, g dbSNP:765681480
1764 1764 a, c dbSNP:556737742
1766 1766 a, g dbSNP:754312564
1770 1770 c, t dbSNP:538884744
1771 1771 a, g dbSNP:761013423
1789 1789 a, g dbSNP:749839120
1789 1789 -, g dbSNP:387906574
1800 1800 c, g dbSNP:763737676
1801 1801 a, g dbSNP:762383899
1802 1802 a, g dbSNP:775017806
1809 1809 a, g dbSNP:769887865
1817 1817 a, g dbSNP:759591318
1818 1818 g, t dbSNP:776690396
1841 1841 c, t dbSNP:559710313
1845 1845 a, g dbSNP:374780587
1854 1854 c, g dbSNP:371971136
1858 1858 g, t dbSNP:372788241
1859 1859 g, t dbSNP:777869197
1877 1877 -, gaaa dbSNP:765576367
1880 1880 a, g dbSNP:2775
1911 1911 g, t dbSNP:553327175
1952 1952 c, g dbSNP:374361465
1961 1961 a, g dbSNP:187827993
2012 2012 a, g dbSNP:549472131
2024 2024 a, c dbSNP:143317618
2065 2065 a, t dbSNP:542748598
2114 2114 c, t dbSNP:775192146
2131 2131 g, t dbSNP:570223278
2137 2137 a, g dbSNP:55923017
2207 2207 a, t dbSNP:781309579
2215 2215 c, t dbSNP:112493228
2216 2216 a, g dbSNP:533678440
2221 2221 -, g dbSNP:556732113
2229 2229 c, t dbSNP:574931385
2243 2243 c, t dbSNP:779037755
2267 2267 a, g dbSNP:182676227
2272 2272 a, g dbSNP:191020661
2308 2308 a, c dbSNP:755220331
2360 2360 c, t dbSNP:1060856
2400 2400 c, g dbSNP:780328831
2453 2453 a, g dbSNP:372065850
2457 2457 a, c dbSNP:367884177
2488 2488 c, t dbSNP:7447380
2502 2502 c, t dbSNP:139905907
2509 2509 c, t dbSNP:544919864
2511 2511 c, t dbSNP:750743133
2538 2538 c, t dbSNP:1060857
2543 2543 a, g dbSNP:1138001
2619 2619 c, g dbSNP:1807
2630 2630 a, g dbSNP:1138005
2710 2710 -, gag dbSNP:543290589
2784 2784 c, t dbSNP:574036505
2792 2792 -, a dbSNP:60217601
2792 2792 a, c dbSNP:74892068
2812 2812 -, aa, aaa dbSNP:368894310
2848 2848 c, g dbSNP:370883463
2865 2865 a, g dbSNP:555808054
2870 2870 c, t dbSNP:111675585
2871 2871 a, g dbSNP:541187121
2920 2920 a, g dbSNP:1483780
2924 2924 g, t dbSNP:80345302
2936 2936 a, c dbSNP:769291143
2951 2951 c, g dbSNP:539682277
2964 2964 c, g dbSNP:146010837
2968 2968 a, c, t dbSNP:181404590
3015 3015 c, t dbSNP:144106312
3021 3021 a, g dbSNP:555172968
3030 3030 c, g dbSNP:372984832
3036 3036 c, t dbSNP:565083629
3094 3094 a, g dbSNP:548608589
3100 3100 a, g dbSNP:190996922
3122 3122 g, t dbSNP:778898407
3147 3147 c, t dbSNP:768755329
3153 3153 a, g dbSNP:139186397
3180 3180 a, t dbSNP:115645125
3197 3197 c, t dbSNP:532956497
3252 3252 a, g dbSNP:559504053
3253 3253 c, t dbSNP:541286622
3258 3258 a, g dbSNP:114580465
3260 3260 a, g dbSNP:576450678
3266 3266 a, g dbSNP:555797762
3335 3335 a, g dbSNP:780351820
3357 3357 c, t dbSNP:555863580
3394 3394 a, g dbSNP:543869348
3484 3484 a, g dbSNP:78029541
3505 3505 a, c dbSNP:557939339
3507 3507 a, t dbSNP:62947162
3514 3514 g, t dbSNP:200532010
3514 3514 -, t dbSNP:5871218
3527 3527 a, c dbSNP:756259873
3542 3542 c, t dbSNP:185960737
3551 3551 a, g dbSNP:566092091
3553 3553 a, t dbSNP:744720
3560 3560 at, tg dbSNP:386692155
3560 3560 a, t dbSNP:744721
3561 3561 -, g dbSNP:199550747
3561 3561 g, t dbSNP:744722
3600 3600 a, g dbSNP:533650761
3616 3616 c, t dbSNP:744723
3639 3639 a, g dbSNP:565927910
3648 3648 a, c dbSNP:763990036
3677 3677 c, t dbSNP:755847753
3696 3696 c, g dbSNP:189465791
3699 3699 a, c dbSNP:569655770
3750 3750 a, g dbSNP:551144920
3779 3779 a, g dbSNP:752477837
3884 3884 c, g dbSNP:553257829
3888 3888 a, c dbSNP:767359075
3898 3898 a, c dbSNP:759427220
3933 3933 c, t dbSNP:375841477
3938 3938 a, g dbSNP:115168957
3942 3942 c, t dbSNP:765274850
3959 3959 a, g dbSNP:752082866
3959 3959 -, g dbSNP:369180172
4002 4002 c, t dbSNP:559274917
4027 4027 g, t dbSNP:762058139
4066 4066 a, t dbSNP:76249070
4079 4079 c, g dbSNP:184630563
4100 4100 c, t dbSNP:764956560
4119 4119 -, t dbSNP:113950002
4126 4126 c, t dbSNP:561998848
4143 4143 a, g dbSNP:543756785
4159 4159 a, g dbSNP:538064274
4193 4193 c, t dbSNP:538927271
4199 4199 a, g dbSNP:116566135
4221 4221 a, c dbSNP:776633516
4231 4231 a, g dbSNP:545933526
4235 4235 c, t dbSNP:114575585
4276 4276 -, t dbSNP:200155555
4304 4304 c, t dbSNP:768166252
4308 4308 c, t dbSNP:769126957
4311 4311 a, g dbSNP:7715516
4318 4318 a, g dbSNP:370442664
4324 4324 a, g dbSNP:76363408
4351 4351 c, g dbSNP:574774962
4361 4361 c, g dbSNP:556404419
4381 4381 -, gc dbSNP:771970643
4387 4387 c, t dbSNP:114287342
4415 4415 a, g dbSNP:74415886
4477 4477 c, t dbSNP:749387811
4479 4479 -, c dbSNP:201421709
4509 4509 c, t dbSNP:368844061
4534 4534 a, g dbSNP:775421792
4576 4576 a, g dbSNP:181028716
4595 4595 a, g dbSNP:148309568
4600 4600 c, g dbSNP:189486979
4610 4610 -, t dbSNP:11395324
4611 4611 -, t dbSNP:59667289
4628 4628 c, t dbSNP:77525381
4630 4630 -, c dbSNP:780063692
4631 4631 -, c dbSNP:370255749
4654 4654 a, g dbSNP:145424881
4696 4696 -, aa dbSNP:542701107
4703 4703 c, t dbSNP:547600980
4709 4709 c, g dbSNP:184098590
4718 4718 c, t dbSNP:746329980
4726 4726 a, t dbSNP:192950824
4741 4741 a, g dbSNP:370866834
4797 4797 c, t dbSNP:550051176
4798 4798 -, t dbSNP:397760043
4798 4798 c, t dbSNP:369855064
4809 4809 -, t dbSNP:5871217
4816 4816 a, g dbSNP:57369925
4834 4834 c, t dbSNP:2035471
4848 4848 a, g dbSNP:756798087
4919 4919 a, g dbSNP:564310704
4922 4922 a, g dbSNP:546222411
4925 4925 c, t dbSNP:749036709
4936 4936 a, g dbSNP:572425402

Target ORF information:

RefSeq Version NM_001182
Organism Homo sapiens (human)
Definition Homo sapiens aldehyde dehydrogenase 7 family, member A1 (ALDH7A1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001182

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGTGGCGCC TTCCTCGCGC GCTGTGTGTG CACGCTGCAA AGACCAGCAA GCTCTCTGGA 
CCTTGGAGCA GGCCTGCCGC CTTCATGTCC ACTCTCCTCA TCAATCAGCC CCAGTATGCG
TGGCTGAAAG AGCTGGGGCT CCGCGAGGAA AACGAGGGCG TGTATAATGG AAGCTGGGGA
GGCCGGGGAG AGGTTATTAC GACCTATTGC CCTGCTAACA ACGAGCCAAT AGCAAGAGTC
CGACAGGCCA GTGTGGCAGA CTATGAAGAA ACTGTAAAGA AAGCAAGAGA AGCATGGAAA
ATCTGGGCAG ATATTCCTGC TCCAAAACGA GGAGAAATAG TAAGACAGAT TGGCGATGCC
TTGCGGGAGA AGATCCAAGT ACTAGGAAGC TTGGTGTCTT TGGAGATGGG GAAAATCTTA
GTGGAAGGTG TGGGTGAAGT TCAGGAGTAT GTGGATATCT GTGACTATGC TGTTGGTTTA
TCAAGGATGA TTGGAGGACC TATCTTGCCT TCTGAAAGAT CTGGCCATGC ACTGATTGAG
CAGTGGAATC CCGTAGGCCT GGTTGGAATC ATCACGGCAT TCAATTTCCC TGTGGCAGTG
TATGGTTGGA ACAACGCCAT CGCCATGATC TGTGGAAATG TCTGCCTCTG GAAAGGAGCT
CCAACCACTT CCCTCATTAG TGTGGCTGTC ACAAAGATAA TAGCCAAGGT TCTGGAGGAC
AACAAGCTGC CTGGTGCAAT TTGTTCCTTG ACTTGTGGTG GAGCAGATAT TGGCACAGCA
ATGGCCAAAG ATGAACGAGT GAACCTGCTG TCCTTCACTG GGAGCACTCA GGTGGGAAAA
CAGGTGGGCC TGATGGTGCA GGAGAGGTTT GGGAGAAGTC TGTTGGAACT TGGAGGAAAC
AATGCCATTA TTGCCTTTGA AGATGCAGAC CTCAGCTTAG TTGTTCCATC AGCTCTCTTC
GCTGCTGTGG GAACAGCTGG CCAGAGGTGT ACCACTGCGA GGCGACTGTT TATACATGAA
AGCATCCATG ATGAGGTTGT AAACAGACTT AAAAAGGCCT ATGCACAGAT CCGAGTTGGG
AACCCATGGG ACCCTAATGT TCTCTATGGG CCACTCCACA CCAAGCAGGC AGTGAGCATG
TTTCTTGGAG CAGTGGAAGA AGCAAAGAAA GAAGGTGGCA CAGTGGTCTA TGGGGGCAAG
GTTATGGATC GCCCTGGAAA TTATGTAGAA CCGACAATTG TGACAGGTCT TGGCCACGAT
GCGTCCATTG CACACACAGA GACTTTTGCT CCGATTCTCT ATGTCTTTAA ATTCAAGAAT
GAAGAAGAGG TCTTTGCATG GAATAATGAA GTAAAACAGG GACTTTCAAG TAGCATCTTT
ACCAAAGATC TGGGCAGAAT CTTTCGCTGG CTTGGACCTA AAGGATCAGA CTGTGGCATT
GTAAATGTCA ACATTCCAAC AAGTGGGGCT GAGATTGGAG GTGCCTTTGG AGGAGAAAAG
CACACTGGTG GTGGCAGGGA GTCTGGCAGT GATGCCTGGA AACAGTACAT GAGAAGGTCT
ACTTGTACTA TCAACTACAG TAAAGACCTT CCTCTGGCCC AAGGAATCAA GTTTCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22668
Accession Version NM_001201377.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1536bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear Document: OHu22668D_COA.pdf (pdf)
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product alpha-aminoadipic semialdehyde dehydrogenase isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC375277.1, BC071712.1, AK021800.1, AC093535.2, DB501575.1, BU153725.1, CD678674.1, BG680326.1, AK123774.1 and AI039375.1. On or before Jan 20, 2011 this sequence version replaced gi:310128086, gi:310128088, gi:310128092, gi:310128090, gi:310128094, gi:310128098, gi:310128096, gi:310128100, gi:310128102. Summary: The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011]. Transcript Variant: This variant (1) encodes two isoforms resulting from the use of alternative in-frame translation initiation codons. The longer isoform (1) is derived from an upstream AUG (at nt 193-195), while the shorter isoform (2) is derived from a downstream AUG (at nt 277-279). This RefSeq represents the shorter isoform, which is found in the cytosol (PMIDs: 20207735 and 19885858). Sequence Note: This Refseq, containing three potential in-frame translation initiation codons (all with weak Kozak signals), is annotated with a CDS starting from a downstream start codon (at nt 277-279), which results in a shorter, soluble isoform that is localized in the cytosol (PMIDs: 20207735 and 19885858). A longer isoform, resulting from the use of an upstream start codon (at nt 193-195) and localized in the mitochondria, is represented in a separate RefSeq (NM_001182.4). The use of another upstream start codon (at nt 112-114) that is present in only a subset of higher mammals, would increase the protein length by another 27 aa. This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: downstream AUG is associated with N-terminal localization signal (PMID:19885858) gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: BC071712.1, S74728.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGTCCACTC TCCTCATCAA TCAGCCCCAG TATGCGTGGC TGAAAGAGCT GGGGCTCCGC 
GAGGAAAACG AGGGCGTGTA TAATGGAAGC TGGGGAGGCC GGGGAGAGGT TATTACGACC
TATTGCCCTG CTAACAACGA GCCAATAGCA AGAGTCCGAC AGGCCAGTGT GGCAGACTAT
GAAGAAACTG TAAAGAAAGC AAGAGAAGCA TGGAAAATCT GGGCAGATAT TCCTGCTCCA
AAACGAGGAG AAATAGTAAG ACAGATTGGC GATGCCTTGC GGGAGAAGAT CCAAGTACTA
GGAAGCTTGG TGTCTTTGGA GATGGGGAAA ATCTTAGTGG AAGGTGTGGG TGAAGTTCAG
GAGTATGTGG ATATCTGTGA CTATGCTGTT GGTTTATCAA GGATGATTGG AGGACCTATC
TTGCCTTCTG AAAGATCTGG CCATGCACTG ATTGAGCAGT GGAATCCCGT AGGCCTGGTT
GGAATCATCA CGGCATTCAA TTTCCCTGTG GCAGTGTATG GTTGGAACAA CGCCATCGCC
ATGATCTGTG GAAATGTCTG CCTCTGGAAA GGAGCTCCAA CCACTTCCCT CATTAGTGTG
GCTGTCACAA AGATAATAGC CAAGGTTCTG GAGGACAACA AGCTGCCTGG TGCAATTTGT
TCCTTGACTT GTGGTGGAGC AGATATTGGC ACAGCAATGG CCAAAGATGA ACGAGTGAAC
CTGCTGTCCT TCACTGGGAG CACTCAGGTG GGAAAACAGG TGGGCCTGAT GGTGCAGGAG
AGGTTTGGGA GAAGTCTGTT GGAACTTGGA GGAAACAATG CCATTATTGC CTTTGAAGAT
GCAGACCTCA GCTTAGTTGT TCCATCAGCT CTCTTCGCTG CTGTGGGAAC AGCTGGCCAG
AGGTGTACCA CTGCGAGGCG ACTGTTTATA CATGAAAGCA TCCATGATGA GGTTGTAAAC
AGACTTAAAA AGGCCTATGC ACAGATCCGA GTTGGGAACC CATGGGACCC TAATGTTCTC
TATGGGCCAC TCCACACCAA GCAGGCAGTG AGCATGTTTC TTGGAGCAGT GGAAGAAGCA
AAGAAAGAAG GTGGCACAGT GGTCTATGGG GGCAAGGTTA TGGATCGCCC TGGAAATTAT
GTAGAACCGA CAATTGTGAC AGGTCTTGGC CACGATGCGT CCATTGCACA CACAGAGACT
TTTGCTCCGA TTCTCTATGT CTTTAAATTC AAGAATGAAG AAGAGGTCTT TGCATGGAAT
AATGAAGTAA AACAGGGACT TTCAAGTAGC ATCTTTACCA AAGATCTGGG CAGAATCTTT
CGCTGGCTTG GACCTAAAGG ATCAGACTGT GGCATTGTAA ATGTCAACAT TCCAACAAGT
GGGGCTGAGA TTGGAGGTGC CTTTGGAGGA GAAAAGCACA CTGGTGGTGG CAGGGAGTCT
GGCAGTGATG CCTGGAAACA GTACATGAGA AGGTCTACTT GTACTATCAA CTACAGTAAA
GACCTTCCTC TGGCCCAAGG AATCAAGTTT CAGTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001188306.1
CDS277..1812
Misc Feature(1)112..114(+)
Misc Feature(2)193..195(+)
Misc Feature(3)349..1773(+)
Misc Feature(4)490..1770(+)
Misc Feature(5)766..1680(+)
Misc Feature(6)775..1182(+)
Exon (1)1..384
Gene:ALDH7A1
Gene Synonym:
Exon (2)385..438
Gene:ALDH7A1
Gene Synonym:
Exon (3)439..504
Gene:ALDH7A1
Gene Synonym:
Exon (4)505..585
Gene:ALDH7A1
Gene Synonym:
Exon (5)586..709
Gene:ALDH7A1
Gene Synonym:
Exon (6)710..842
Gene:ALDH7A1
Gene Synonym:
Exon (7)843..887
Gene:ALDH7A1
Gene Synonym:
Exon (8)888..965
Gene:ALDH7A1
Gene Synonym:
Exon (9)966..1063
Gene:ALDH7A1
Gene Synonym:
Exon (10)1064..1105
Gene:ALDH7A1
Gene Synonym:
Exon (11)1106..1200
Gene:ALDH7A1
Gene Synonym:
Exon (12)1201..1285
Gene:ALDH7A1
Gene Synonym:
Exon (13)1286..1392
Gene:ALDH7A1
Gene Synonym:
Exon (14)1393..1509
Gene:ALDH7A1
Gene Synonym:
Exon (15)1510..1607
Gene:ALDH7A1
Gene Synonym:
Exon (16)1608..1681
Gene:ALDH7A1
Gene Synonym:
Exon (17)1682..1757
Gene:ALDH7A1
Gene Synonym:
Exon (18)1758..4936
Gene:ALDH7A1
Gene Synonym:
Translation
Position Chain Variation Link
35 35 g, t dbSNP:563329202
42 42 c, t dbSNP:900640
55 55 a, t dbSNP:577761503
61 61 a, c dbSNP:900641
64 64 a, c dbSNP:532564619
65 65 c, g dbSNP:768908360
75 75 a, c dbSNP:752916959
76 76 g, t dbSNP:146562077
93 93 a, g dbSNP:780114646
113 113 g, t dbSNP:563928852
123 123 c, t dbSNP:746337997
124 124 a, g dbSNP:573822035
129 129 a, g dbSNP:757747897
132 132 g, t dbSNP:751940730
133 133 a, g dbSNP:144272515
138 138 -, gctctatttcagc dbSNP:756450524
139 139 c, t dbSNP:537006969
159 159 c, g, t dbSNP:140627539
162 162 a, c dbSNP:765830909
163 163 c, t dbSNP:760633380
164 164 c, t dbSNP:556650006
165 165 c, t dbSNP:767418609
170 170 g, t dbSNP:761568340
180 180 g, t dbSNP:774190967
186 186 g, t dbSNP:768763698
190 190 a, c dbSNP:763177883
191 191 a, g dbSNP:763823758
200 200 a, g dbSNP:759866910
201 201 c, t dbSNP:770033340
205 205 c, t dbSNP:745921838
208 208 c, t dbSNP:781779462
210 210 c, t dbSNP:771562794
217 217 c, t dbSNP:747342957
223 223 c, g dbSNP:778144937
224 224 a, t dbSNP:754614105
225 225 c, g dbSNP:753485531
226 226 -, g dbSNP:750693623
228 228 c, t dbSNP:779646478
230 230 c, g dbSNP:367820135
231 231 a, g dbSNP:201566142
235 235 a, t dbSNP:1049211
238 238 -, acca dbSNP:767805540
247 247 c, t dbSNP:749919953
248 248 c, g dbSNP:566243475
252 252 a, t dbSNP:1049214
255 255 c, t dbSNP:368427726
258 258 c, g dbSNP:1049217
261 261 c, t dbSNP:763900156
265 265 c, t dbSNP:762624752
270 270 c, t dbSNP:11542969
274 274 c, t dbSNP:775904572
277 277 a, g dbSNP:765544488
284 284 c, t dbSNP:759758133
285 285 g, t dbSNP:776788391
287 287 a, t dbSNP:375009404
289 289 c, t dbSNP:771357813
292 292 -, a dbSNP:761986050
292 292 a, g dbSNP:747505504
294 294 c, g dbSNP:773484446
296 296 a, g dbSNP:547648880
300 300 c, g, t dbSNP:779736481
303 303 c, t dbSNP:372328305
309 309 g, t dbSNP:755756776
311 311 c, t dbSNP:745385277
325 325 a, c, t dbSNP:757162735
327 327 a, g dbSNP:751474057
330 330 a, g dbSNP:770975428
331 331 c, t dbSNP:144684547
333 333 a, c dbSNP:763915613
342 342 a, t dbSNP:758272364
345 345 c, t dbSNP:752537865
346 346 c, g dbSNP:765562932
375 375 a, c dbSNP:374526203
378 378 a, g dbSNP:776876925
379 379 a, g, t dbSNP:760636660
392 392 a, c, t dbSNP:543181020
393 393 a, g, t dbSNP:747643987
395 395 a, c dbSNP:58528748
399 399 c, t dbSNP:369516597
400 400 c, t dbSNP:768706976
415 415 a, g dbSNP:749111036
418 418 c, t dbSNP:779654060
421 421 a, c dbSNP:756379659
424 424 a, g dbSNP:750569691
427 427 a, g dbSNP:794727259
428 428 c, g dbSNP:781361567
433 433 c, t dbSNP:757377110
435 435 a, g dbSNP:146438406
438 438 a, g dbSNP:755397405
442 442 a, c dbSNP:775388343
443 443 a, g dbSNP:769518060
447 447 a, g dbSNP:745653970
454 454 c, t dbSNP:368517032
455 455 a, t dbSNP:376294954
457 457 c, g dbSNP:747103219
465 465 c, t dbSNP:60720055
468 468 a, g dbSNP:758973869
475 475 a, g dbSNP:551163406
477 477 -, g dbSNP:758414053
477 477 a, c dbSNP:754969438
479 479 g, t dbSNP:765748549
486 486 a, t dbSNP:755352873
520 520 c, g, t dbSNP:121912708
523 523 g, t dbSNP:763780569
537 537 a, g dbSNP:762428797
542 542 c, t dbSNP:749853326
546 546 c, t dbSNP:149228266
548 548 a, g dbSNP:765099324
550 550 c, g dbSNP:759418993
551 551 a, c, g, t dbSNP:549279821
554 554 c, t dbSNP:145329188
556 556 c, t dbSNP:370624118
565 565 a, g dbSNP:117295656
578 578 a, g dbSNP:778997049
586 586 a, g dbSNP:760527001
607 607 a, c dbSNP:772989605
609 609 c, t dbSNP:772201739
615 615 c, g dbSNP:199653162
621 621 g, t dbSNP:774328460
624 624 a, g dbSNP:768899130
627 627 g, t dbSNP:749358074
634 634 c, g, t dbSNP:551773096
642 642 c, t dbSNP:375095250
677 677 a, g dbSNP:781569684
678 678 g, t dbSNP:758016489
683 683 c, t dbSNP:747873042
686 686 c, g dbSNP:375491094
687 687 a, g dbSNP:754537923
694 694 a, g dbSNP:753339039
711 711 a, t dbSNP:200447936
714 714 g, t dbSNP:756081030
717 717 c, t dbSNP:750418342
719 719 a, g dbSNP:767336581
720 720 c, t dbSNP:757135576
721 721 c, g dbSNP:140102105
722 722 a, c dbSNP:764417585
724 724 -, ctgattgagca dbSNP:765119568
728 728 c, t dbSNP:763217060
730 730 a, g dbSNP:775743077
742 742 c, g dbSNP:765445537
744 744 c, t dbSNP:369859575
745 745 a, g, t dbSNP:61757685
751 751 c, t dbSNP:771335275
767 767 c, t dbSNP:376917645
769 769 a, g dbSNP:773503933
776 776 a, g dbSNP:372660425
780 780 c, t dbSNP:748904145
781 781 c, t dbSNP:779652673
784 784 a, g dbSNP:769398736
788 788 c, t dbSNP:121912709
789 789 a, g dbSNP:745357569
794 794 a, g dbSNP:781259686
799 799 g, t dbSNP:555896752
807 807 c, t dbSNP:369380330
811 811 a, g dbSNP:777670051
813 813 c, t dbSNP:758236544
814 814 a, g dbSNP:753014428
815 815 c, t dbSNP:200433565
819 819 a, g dbSNP:765542228
822 822 c, g dbSNP:759724393
831 831 c, t dbSNP:537260194
838 838 c, t dbSNP:753791407
848 848 c, g dbSNP:202084501
856 856 a, g dbSNP:777829351
857 857 c, t dbSNP:140827978
858 858 c, t dbSNP:758324700
865 865 c, t dbSNP:752533662
867 867 c, t dbSNP:57902950
871 871 a, g dbSNP:755093525
874 874 a, g dbSNP:201832111
880 880 a, g dbSNP:752824129
891 891 a, t dbSNP:756247675
898 898 a, g dbSNP:750500704
909 909 a, g dbSNP:768018240
912 912 c, t dbSNP:757704473
913 913 a, c dbSNP:751944211
922 922 a, c dbSNP:140701322
940 940 a, t dbSNP:763353456
962 962 c, t dbSNP:776202861
972 972 a, g dbSNP:772877760
973 973 a, g dbSNP:767172222
994 994 a, t dbSNP:761387197
999 999 a, g dbSNP:774216010
1016 1016 a, g dbSNP:768638552
1021 1021 c, g dbSNP:369271104
1024 1024 -, g dbSNP:746295168
1026 1026 a, c, g, t dbSNP:201948406
1031 1031 a, g dbSNP:746052220
1034 1034 a, g dbSNP:781369461
1035 1035 c, g dbSNP:771054683
1044 1044 c, g dbSNP:747107627
1045 1045 a, g dbSNP:778146305
1050 1050 a, g dbSNP:150623275
1067 1067 g, t dbSNP:756879600
1074 1074 c, g dbSNP:751053781
1076 1076 g, t dbSNP:763620908
1091 1091 a, c dbSNP:762340782
1094 1094 a, t dbSNP:121912711
1099 1099 a, g dbSNP:765153843
1106 1106 c, g dbSNP:141775154
1115 1115 a, g dbSNP:767632811
1122 1122 c, t dbSNP:202069068
1132 1132 c, g dbSNP:774519989
1139 1139 -, c dbSNP:778003597
1139 1139 c, t dbSNP:572990686
1142 1142 c, t dbSNP:148052962
1147 1147 c, g dbSNP:775830338
1152 1152 c, t dbSNP:114516357
1153 1153 a, g dbSNP:746212816
1154 1154 c, t dbSNP:3189320
1157 1157 c, t dbSNP:777483675
1179 1179 a, g dbSNP:761295869
1187 1187 c, g dbSNP:543182575
1190 1190 c, t dbSNP:144625212
1191 1191 a, g dbSNP:563675719
1192 1192 a, g dbSNP:111319259
1196 1196 a, g dbSNP:754449549
1202 1202 g, t dbSNP:747834606
1204 1204 a, g dbSNP:374248561
1207 1207 c, t dbSNP:768210262
1208 1208 a, g dbSNP:199767457
1209 1209 c, t dbSNP:200394848
1214 1214 a, g dbSNP:141701364
1215 1215 c, t dbSNP:750258751
1228 1228 a, g dbSNP:780813341
1231 1231 a, g dbSNP:757087792
1235 1235 a, g dbSNP:751879860
1238 1238 c, g dbSNP:553114356
1243 1243 a, g dbSNP:763193538
1251 1251 c, t dbSNP:752660981
1255 1255 a, g dbSNP:765795361
1257 1257 a, g dbSNP:759921213
1258 1258 c, g dbSNP:138675705
1260 1260 a, g dbSNP:376004978
1261 1261 a, g dbSNP:761011399
1262 1262 c, t dbSNP:774055048
1264 1264 c, t dbSNP:768233031
1265 1265 g, t dbSNP:144671885
1268 1268 c, t dbSNP:201752552
1272 1272 a, g dbSNP:779387233
1276 1276 c, t dbSNP:532800318
1277 1277 c, t dbSNP:745833299
1280 1280 a, g dbSNP:781254582
1285 1285 c, t dbSNP:370869432
1305 1305 a, g dbSNP:755077088
1318 1318 a, c, t dbSNP:564187364
1321 1321 a, g dbSNP:750205677
1325 1325 c, t dbSNP:7447092
1342 1342 a, g dbSNP:140947675
1348 1348 a, g dbSNP:756568507
1352 1352 a, c dbSNP:750821093
1359 1359 a, g dbSNP:767913793
1362 1362 a, g dbSNP:544253617
1375 1375 a, g dbSNP:373304485
1378 1378 a, g dbSNP:764939934
1382 1382 a, t dbSNP:758974665
1402 1402 c, t dbSNP:181287032
1403 1403 a, g dbSNP:771975420
1404 1404 c, t dbSNP:761523599
1409 1409 c, g dbSNP:774148433
1416 1416 c, g, t dbSNP:121912710
1424 1424 c, t dbSNP:780233639
1425 1425 a, g dbSNP:572831296
1426 1426 a, g dbSNP:2306618
1429 1429 a, g dbSNP:201792544
1435 1435 a, t dbSNP:757726867
1436 1436 c, g dbSNP:751898560
1449 1449 c, t dbSNP:778236831
1450 1450 a, g dbSNP:758810390
1454 1454 c, t dbSNP:753598402
1455 1455 a, g dbSNP:587780850
1459 1459 a, g dbSNP:760266177
1464 1464 a, g dbSNP:749889093
1467 1467 c, t dbSNP:767375552
1468 1468 a, g dbSNP:150305320
1469 1469 c, t dbSNP:774126237
1471 1471 c, g dbSNP:121912707
1476 1476 a, t dbSNP:762723665
1478 1478 c, t dbSNP:775759943
1479 1479 c, t dbSNP:375030056
1484 1484 c, t dbSNP:151107837
1485 1485 a, g dbSNP:538504116
1488 1488 g, t dbSNP:372127110
1489 1489 c, t dbSNP:548996847
1493 1493 -, at dbSNP:753671880
1493 1493 a, g dbSNP:747597620
1495 1495 a, g dbSNP:778125731
1497 1497 c, g dbSNP:142975776
1507 1507 a, c dbSNP:12514417
1512 1512 c, t dbSNP:755365818
1521 1521 a, g dbSNP:745584430
1527 1527 c, t dbSNP:780696540
1541 1541 a, g dbSNP:200299784
1542 1542 a, g dbSNP:200980969
1548 1548 a, c dbSNP:756859037
1552 1552 g, t dbSNP:750971835
1561 1561 a, c dbSNP:764036426
1567 1567 a, g, t dbSNP:186558364
1576 1576 a, g dbSNP:375090702
1588 1588 a, g dbSNP:113609617
1597 1597 c, t dbSNP:752523070
1598 1598 a, g dbSNP:147940248
1599 1599 c, g dbSNP:759234889
1603 1603 -, g dbSNP:772766995
1626 1626 -, tg dbSNP:770492145
1634 1634 c, t dbSNP:144701796
1649 1649 c, t dbSNP:766645306
1651 1651 -, a dbSNP:760092559
1652 1652 -, caa dbSNP:777187854
1653 1653 a, g dbSNP:372488916
1656 1656 c, t dbSNP:750640713
1669 1669 g, t dbSNP:767756650
1673 1673 g, t dbSNP:763418390
1678 1678 c, t dbSNP:202104680
1682 1682 g, t dbSNP:751635252
1683 1683 a, g dbSNP:764688935
1698 1698 c, t dbSNP:565405031
1705 1705 c, g dbSNP:556400964
1707 1707 c, t dbSNP:765576421
1712 1712 a, c, g dbSNP:80049945
1713 1713 a, g dbSNP:540451615
1726 1726 a, g dbSNP:771651423
1739 1739 a, g dbSNP:200102503
1742 1742 c, t dbSNP:773694788
1745 1745 a, c, g dbSNP:749231711
1748 1748 a, g dbSNP:561343926
1753 1753 a, g dbSNP:755930241
1756 1756 a, t dbSNP:745592760
1759 1759 a, g dbSNP:61757684
1762 1762 a, g dbSNP:765681480
1764 1764 a, c dbSNP:556737742
1766 1766 a, g dbSNP:754312564
1770 1770 c, t dbSNP:538884744
1771 1771 a, g dbSNP:761013423
1789 1789 a, g dbSNP:749839120
1789 1789 -, g dbSNP:387906574
1800 1800 c, g dbSNP:763737676
1801 1801 a, g dbSNP:762383899
1802 1802 a, g dbSNP:775017806
1809 1809 a, g dbSNP:769887865
1817 1817 a, g dbSNP:759591318
1818 1818 g, t dbSNP:776690396
1841 1841 c, t dbSNP:559710313
1845 1845 a, g dbSNP:374780587
1854 1854 c, g dbSNP:371971136
1858 1858 g, t dbSNP:372788241
1859 1859 g, t dbSNP:777869197
1877 1877 -, gaaa dbSNP:765576367
1880 1880 a, g dbSNP:2775
1911 1911 g, t dbSNP:553327175
1952 1952 c, g dbSNP:374361465
1961 1961 a, g dbSNP:187827993
2012 2012 a, g dbSNP:549472131
2024 2024 a, c dbSNP:143317618
2065 2065 a, t dbSNP:542748598
2114 2114 c, t dbSNP:775192146
2131 2131 g, t dbSNP:570223278
2137 2137 a, g dbSNP:55923017
2207 2207 a, t dbSNP:781309579
2215 2215 c, t dbSNP:112493228
2216 2216 a, g dbSNP:533678440
2221 2221 -, g dbSNP:556732113
2229 2229 c, t dbSNP:574931385
2243 2243 c, t dbSNP:779037755
2267 2267 a, g dbSNP:182676227
2272 2272 a, g dbSNP:191020661
2308 2308 a, c dbSNP:755220331
2360 2360 c, t dbSNP:1060856
2400 2400 c, g dbSNP:780328831
2453 2453 a, g dbSNP:372065850
2457 2457 a, c dbSNP:367884177
2488 2488 c, t dbSNP:7447380
2502 2502 c, t dbSNP:139905907
2509 2509 c, t dbSNP:544919864
2511 2511 c, t dbSNP:750743133
2538 2538 c, t dbSNP:1060857
2543 2543 a, g dbSNP:1138001
2619 2619 c, g dbSNP:1807
2630 2630 a, g dbSNP:1138005
2710 2710 -, gag dbSNP:543290589
2784 2784 c, t dbSNP:574036505
2792 2792 -, a dbSNP:60217601
2792 2792 a, c dbSNP:74892068
2812 2812 -, aa, aaa dbSNP:368894310
2848 2848 c, g dbSNP:370883463
2865 2865 a, g dbSNP:555808054
2870 2870 c, t dbSNP:111675585
2871 2871 a, g dbSNP:541187121
2920 2920 a, g dbSNP:1483780
2924 2924 g, t dbSNP:80345302
2936 2936 a, c dbSNP:769291143
2951 2951 c, g dbSNP:539682277
2964 2964 c, g dbSNP:146010837
2968 2968 a, c, t dbSNP:181404590
3015 3015 c, t dbSNP:144106312
3021 3021 a, g dbSNP:555172968
3030 3030 c, g dbSNP:372984832
3036 3036 c, t dbSNP:565083629
3094 3094 a, g dbSNP:548608589
3100 3100 a, g dbSNP:190996922
3122 3122 g, t dbSNP:778898407
3147 3147 c, t dbSNP:768755329
3153 3153 a, g dbSNP:139186397
3180 3180 a, t dbSNP:115645125
3197 3197 c, t dbSNP:532956497
3252 3252 a, g dbSNP:559504053
3253 3253 c, t dbSNP:541286622
3258 3258 a, g dbSNP:114580465
3260 3260 a, g dbSNP:576450678
3266 3266 a, g dbSNP:555797762
3335 3335 a, g dbSNP:780351820
3357 3357 c, t dbSNP:555863580
3394 3394 a, g dbSNP:543869348
3484 3484 a, g dbSNP:78029541
3505 3505 a, c dbSNP:557939339
3507 3507 a, t dbSNP:62947162
3514 3514 g, t dbSNP:200532010
3514 3514 -, t dbSNP:5871218
3527 3527 a, c dbSNP:756259873
3542 3542 c, t dbSNP:185960737
3551 3551 a, g dbSNP:566092091
3553 3553 a, t dbSNP:744720
3560 3560 at, tg dbSNP:386692155
3560 3560 a, t dbSNP:744721
3561 3561 -, g dbSNP:199550747
3561 3561 g, t dbSNP:744722
3600 3600 a, g dbSNP:533650761
3616 3616 c, t dbSNP:744723
3639 3639 a, g dbSNP:565927910
3648 3648 a, c dbSNP:763990036
3677 3677 c, t dbSNP:755847753
3696 3696 c, g dbSNP:189465791
3699 3699 a, c dbSNP:569655770
3750 3750 a, g dbSNP:551144920
3779 3779 a, g dbSNP:752477837
3884 3884 c, g dbSNP:553257829
3888 3888 a, c dbSNP:767359075
3898 3898 a, c dbSNP:759427220
3933 3933 c, t dbSNP:375841477
3938 3938 a, g dbSNP:115168957
3942 3942 c, t dbSNP:765274850
3959 3959 a, g dbSNP:752082866
3959 3959 -, g dbSNP:369180172
4002 4002 c, t dbSNP:559274917
4027 4027 g, t dbSNP:762058139
4066 4066 a, t dbSNP:76249070
4079 4079 c, g dbSNP:184630563
4100 4100 c, t dbSNP:764956560
4119 4119 -, t dbSNP:113950002
4126 4126 c, t dbSNP:561998848
4143 4143 a, g dbSNP:543756785
4159 4159 a, g dbSNP:538064274
4193 4193 c, t dbSNP:538927271
4199 4199 a, g dbSNP:116566135
4221 4221 a, c dbSNP:776633516
4231 4231 a, g dbSNP:545933526
4235 4235 c, t dbSNP:114575585
4276 4276 -, t dbSNP:200155555
4304 4304 c, t dbSNP:768166252
4308 4308 c, t dbSNP:769126957
4311 4311 a, g dbSNP:7715516
4318 4318 a, g dbSNP:370442664
4324 4324 a, g dbSNP:76363408
4351 4351 c, g dbSNP:574774962
4361 4361 c, g dbSNP:556404419
4381 4381 -, gc dbSNP:771970643
4387 4387 c, t dbSNP:114287342
4415 4415 a, g dbSNP:74415886
4477 4477 c, t dbSNP:749387811
4479 4479 -, c dbSNP:201421709
4509 4509 c, t dbSNP:368844061
4534 4534 a, g dbSNP:775421792
4576 4576 a, g dbSNP:181028716
4595 4595 a, g dbSNP:148309568
4600 4600 c, g dbSNP:189486979
4610 4610 -, t dbSNP:11395324
4611 4611 -, t dbSNP:59667289
4628 4628 c, t dbSNP:77525381
4630 4630 -, c dbSNP:780063692
4631 4631 -, c dbSNP:370255749
4654 4654 a, g dbSNP:145424881
4696 4696 -, aa dbSNP:542701107
4703 4703 c, t dbSNP:547600980
4709 4709 c, g dbSNP:184098590
4718 4718 c, t dbSNP:746329980
4726 4726 a, t dbSNP:192950824
4741 4741 a, g dbSNP:370866834
4797 4797 c, t dbSNP:550051176
4798 4798 -, t dbSNP:397760043
4798 4798 c, t dbSNP:369855064
4809 4809 -, t dbSNP:5871217
4816 4816 a, g dbSNP:57369925
4834 4834 c, t dbSNP:2035471
4848 4848 a, g dbSNP:756798087
4919 4919 a, g dbSNP:564310704
4922 4922 a, g dbSNP:546222411
4925 4925 c, t dbSNP:749036709
4936 4936 a, g dbSNP:572425402

Target ORF information:

RefSeq Version NM_001201377
Organism Homo sapiens (human)
Definition Homo sapiens aldehyde dehydrogenase 7 family, member A1 (ALDH7A1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001201377

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGTCCACTC TCCTCATCAA TCAGCCCCAG TATGCGTGGC TGAAAGAGCT GGGGCTCCGC 
GAGGAAAACG AGGGCGTGTA TAATGGAAGC TGGGGAGGCC GGGGAGAGGT TATTACGACC
TATTGCCCTG CTAACAACGA GCCAATAGCA AGAGTCCGAC AGGCCAGTGT GGCAGACTAT
GAAGAAACTG TAAAGAAAGC AAGAGAAGCA TGGAAAATCT GGGCAGATAT TCCTGCTCCA
AAACGAGGAG AAATAGTAAG ACAGATTGGC GATGCCTTGC GGGAGAAGAT CCAAGTACTA
GGAAGCTTGG TGTCTTTGGA GATGGGGAAA ATCTTAGTGG AAGGTGTGGG TGAAGTTCAG
GAGTATGTGG ATATCTGTGA CTATGCTGTT GGTTTATCAA GGATGATTGG AGGACCTATC
TTGCCTTCTG AAAGATCTGG CCATGCACTG ATTGAGCAGT GGAATCCCGT AGGCCTGGTT
GGAATCATCA CGGCATTCAA TTTCCCTGTG GCAGTGTATG GTTGGAACAA CGCCATCGCC
ATGATCTGTG GAAATGTCTG CCTCTGGAAA GGAGCTCCAA CCACTTCCCT CATTAGTGTG
GCTGTCACAA AGATAATAGC CAAGGTTCTG GAGGACAACA AGCTGCCTGG TGCAATTTGT
TCCTTGACTT GTGGTGGAGC AGATATTGGC ACAGCAATGG CCAAAGATGA ACGAGTGAAC
CTGCTGTCCT TCACTGGGAG CACTCAGGTG GGAAAACAGG TGGGCCTGAT GGTGCAGGAG
AGGTTTGGGA GAAGTCTGTT GGAACTTGGA GGAAACAATG CCATTATTGC CTTTGAAGAT
GCAGACCTCA GCTTAGTTGT TCCATCAGCT CTCTTCGCTG CTGTGGGAAC AGCTGGCCAG
AGGTGTACCA CTGCGAGGCG ACTGTTTATA CATGAAAGCA TCCATGATGA GGTTGTAAAC
AGACTTAAAA AGGCCTATGC ACAGATCCGA GTTGGGAACC CATGGGACCC TAATGTTCTC
TATGGGCCAC TCCACACCAA GCAGGCAGTG AGCATGTTTC TTGGAGCAGT GGAAGAAGCA
AAGAAAGAAG GTGGCACAGT GGTCTATGGG GGCAAGGTTA TGGATCGCCC TGGAAATTAT
GTAGAACCGA CAATTGTGAC AGGTCTTGGC CACGATGCGT CCATTGCACA CACAGAGACT
TTTGCTCCGA TTCTCTATGT CTTTAAATTC AAGAATGAAG AAGAGGTCTT TGCATGGAAT
AATGAAGTAA AACAGGGACT TTCAAGTAGC ATCTTTACCA AAGATCTGGG CAGAATCTTT
CGCTGGCTTG GACCTAAAGG ATCAGACTGT GGCATTGTAA ATGTCAACAT TCCAACAAGT
GGGGCTGAGA TTGGAGGTGC CTTTGGAGGA GAAAAGCACA CTGGTGGTGG CAGGGAGTCT
GGCAGTGATG CCTGGAAACA GTACATGAGA AGGTCTACTT GTACTATCAA CTACAGTAAA
GACCTTCCTC TGGCCCAAGG AATCAAGTTT CAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22641
Accession Version NM_001202404.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1509bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product alpha-aminoadipic semialdehyde dehydrogenase isoform 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC375277.1, BC071712.1, AK297365.1, AK021800.1, AC093535.2, DB501575.1, BU153725.1, CD678674.1, BG680326.1, AK123774.1 and AI039375.1. Summary: The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011]. Transcript Variant: This variant (2) is missing two in-frame coding exons compared to variant 1, resulting in a shorter isoform (3) lacking an internal protein segment compared to isoform 1. Sequence Note: This Refseq, containing three potential in-frame translation initiation codons (all with weak Kozak signals), is annotated with a CDS starting from the upstream start codon (at nt 112-114). While this variant has transcript support, the localization and/or function of this isoform is not known. Translation from the downstream AUGs (at nt 193-195 and 277-279) may occur by leaky scanning. This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: AK297365.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGGTTCTC CCGGGCGGGG GGCGGGGCTC TATTTCAGCA GCTCTCAGGG CCTTGGGCTC 
ATCCCGAGTC CCGGGCTCAG TATGTGGCGC CTTCCTCGCG CGCTGTGTGT GCACGCTGCA
AAGACCAGCA AGCTCTCTGG ACCTTGGAGC AGGCCTGCCG CCTTCATGTC CACTCTCCTC
ATCAATCAGC CCCAGTATGC GTGGCTGAAA GAGCTGGGGC TCCGCGAGGA AAACGAGGGC
GTGTATAATG GAAGCTGGGG AGGCCGGGGA GAGGTTATTA CGACCTATTG CCCTGCTAAC
AACGAGCCAA TAGCAAGAGT CCGACAGGCC AGTGTGGCAG ACTATGAAGA AACTGTAAAG
AAAGCAAGAG AAGCATGGAA AATCTGGGCA GATATTCCTG CTCCAAAACG AGGAGAAATA
GTAAGACAGA TTGGCGATGC CTTGCGGGAG AAGATCCAAG TACTAGGAAG CTTGGTGTCT
TTGGAGATGG GGAAAATCTT AGTGGAAGGT GTGGGTGAAG TTCAGGAGTA TGTGGATATC
TGTGACTATG CTGTTGGTTT ATCAAGGATG ATTGGAGGAC CTATCTTGCC TTCTGAAAGA
TCTGGCCATG CACTGATTGA GCAGTGGAAT CCCGTAGGCC TGGTTGGAAT CATCACGGCA
TTCAATTTCC CTGTGGCAGT GTATGGTTGG AACAACGCCA TCGCCATGAT CTGTGGAAAT
GTCTGCCTCT GGAAAGGAGC TCCAACCACT TCCCTCATTA GTGTGGCTGT CACAAAGATA
ATAGCCAAGG TTCTGGAGGA CAACAAGCTG CCTGGTGCAA TTTGTTCCTT GACTTGTGGT
GGAGCAGATA TTGGCACAGC AATGGCCAAA GATGAACGAG TGAACCTGCT GTCCTTCACT
GGGAGCACTC AGGTGGGAAA ACAGGTGGGC CTGATGGTGC AGGAGAGGTT TGGGAGAAGT
CTGTTGGAAC TTGGAGGAAA CAATGCCATT ATTGCCTTTG AAGATGCAGA CCTCAGCTTA
GTTGTTCCAT CAGCTCTCTT CGCTGCTGTG GGAACAGCTG GCCAGAGGTG TACCACTGCG
AGGCGACTGG TTATGGATCG CCCTGGAAAT TATGTAGAAC CGACAATTGT GACAGGTCTT
GGCCACGATG CGTCCATTGC ACACACAGAG ACTTTTGCTC CGATTCTCTA TGTCTTTAAA
TTCAAGAATG AAGAAGAGGT CTTTGCATGG AATAATGAAG TAAAACAGGG ACTTTCAAGT
AGCATCTTTA CCAAAGATCT GGGCAGAATC TTTCGCTGGC TTGGACCTAA AGGATCAGAC
TGTGGCATTG TAAATGTCAA CATTCCAACA AGTGGGGCTG AGATTGGAGG TGCCTTTGGA
GGAGAAAAGC ACACTGGTGG TGGCAGGGAG TCTGGCAGTG ATGCCTGGAA ACAGTACATG
AGAAGGTCTA CTTGTACTAT CAACTACAGT AAAGACCTTC CTCTGGCCCA AGGAATCAAG
TTTCAGTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001189333.1
CDS112..1620
Misc Feature(1)349..1581(+)
Misc Feature(2)490..1578(+)
Misc Feature(3)766..1488(+)
Misc Feature(4)775..1182(+)
Misc Feature(5)193..195(+)
Misc Feature(6)277..279(+)
Exon (1)1..384
Gene:ALDH7A1
Gene Synonym:
Exon (2)385..438
Gene:ALDH7A1
Gene Synonym:
Exon (3)439..504
Gene:ALDH7A1
Gene Synonym:
Exon (4)505..585
Gene:ALDH7A1
Gene Synonym:
Exon (5)586..709
Gene:ALDH7A1
Gene Synonym:
Exon (6)710..842
Gene:ALDH7A1
Gene Synonym:
Exon (7)843..887
Gene:ALDH7A1
Gene Synonym:
Exon (8)888..965
Gene:ALDH7A1
Gene Synonym:
Exon (9)966..1063
Gene:ALDH7A1
Gene Synonym:
Exon (10)1064..1105
Gene:ALDH7A1
Gene Synonym:
Exon (11)1106..1200
Gene:ALDH7A1
Gene Synonym:
Exon (12)1201..1317
Gene:ALDH7A1
Gene Synonym:
Exon (13)1318..1415
Gene:ALDH7A1
Gene Synonym:
Exon (14)1416..1489
Gene:ALDH7A1
Gene Synonym:
Exon (15)1490..1565
Gene:ALDH7A1
Gene Synonym:
Exon (16)1566..4744
Gene:ALDH7A1
Gene Synonym:
Translation
Position Chain Variation Link
35 35 g, t dbSNP:563329202
42 42 c, t dbSNP:900640
55 55 a, t dbSNP:577761503
61 61 a, c dbSNP:900641
64 64 a, c dbSNP:532564619
65 65 c, g dbSNP:768908360
75 75 a, c dbSNP:752916959
76 76 g, t dbSNP:146562077
93 93 a, g dbSNP:780114646
113 113 g, t dbSNP:563928852
123 123 c, t dbSNP:746337997
124 124 a, g dbSNP:573822035
129 129 a, g dbSNP:757747897
132 132 g, t dbSNP:751940730
133 133 a, g dbSNP:144272515
138 138 -, gctctatttcagc dbSNP:756450524
139 139 c, t dbSNP:537006969
159 159 c, g, t dbSNP:140627539
162 162 a, c dbSNP:765830909
163 163 c, t dbSNP:760633380
164 164 c, t dbSNP:556650006
165 165 c, t dbSNP:767418609
170 170 g, t dbSNP:761568340
180 180 g, t dbSNP:774190967
186 186 g, t dbSNP:768763698
190 190 a, c dbSNP:763177883
191 191 a, g dbSNP:763823758
200 200 a, g dbSNP:759866910
201 201 c, t dbSNP:770033340
205 205 c, t dbSNP:745921838
208 208 c, t dbSNP:781779462
210 210 c, t dbSNP:771562794
217 217 c, t dbSNP:747342957
223 223 c, g dbSNP:778144937
224 224 a, t dbSNP:754614105
225 225 c, g dbSNP:753485531
226 226 -, g dbSNP:750693623
228 228 c, t dbSNP:779646478
230 230 c, g dbSNP:367820135
231 231 a, g dbSNP:201566142
235 235 a, t dbSNP:1049211
238 238 -, acca dbSNP:767805540
247 247 c, t dbSNP:749919953
248 248 c, g dbSNP:566243475
252 252 a, t dbSNP:1049214
255 255 c, t dbSNP:368427726
258 258 c, g dbSNP:1049217
261 261 c, t dbSNP:763900156
265 265 c, t dbSNP:762624752
270 270 c, t dbSNP:11542969
274 274 c, t dbSNP:775904572
277 277 a, g dbSNP:765544488
284 284 c, t dbSNP:759758133
285 285 g, t dbSNP:776788391
287 287 a, t dbSNP:375009404
289 289 c, t dbSNP:771357813
292 292 -, a dbSNP:761986050
292 292 a, g dbSNP:747505504
294 294 c, g dbSNP:773484446
296 296 a, g dbSNP:547648880
300 300 c, g, t dbSNP:779736481
303 303 c, t dbSNP:372328305
309 309 g, t dbSNP:755756776
311 311 c, t dbSNP:745385277
325 325 a, c, t dbSNP:757162735
327 327 a, g dbSNP:751474057
330 330 a, g dbSNP:770975428
331 331 c, t dbSNP:144684547
333 333 a, c dbSNP:763915613
342 342 a, t dbSNP:758272364
345 345 c, t dbSNP:752537865
346 346 c, g dbSNP:765562932
375 375 a, c dbSNP:374526203
378 378 a, g dbSNP:776876925
379 379 a, g, t dbSNP:760636660
392 392 a, c, t dbSNP:543181020
393 393 a, g, t dbSNP:747643987
395 395 a, c dbSNP:58528748
399 399 c, t dbSNP:369516597
400 400 c, t dbSNP:768706976
415 415 a, g dbSNP:749111036
418 418 c, t dbSNP:779654060
421 421 a, c dbSNP:756379659
424 424 a, g dbSNP:750569691
427 427 a, g dbSNP:794727259
428 428 c, g dbSNP:781361567
433 433 c, t dbSNP:757377110
435 435 a, g dbSNP:146438406
438 438 a, g dbSNP:755397405
442 442 a, c dbSNP:775388343
443 443 a, g dbSNP:769518060
447 447 a, g dbSNP:745653970
454 454 c, t dbSNP:368517032
455 455 a, t dbSNP:376294954
457 457 c, g dbSNP:747103219
465 465 c, t dbSNP:60720055
468 468 a, g dbSNP:758973869
475 475 a, g dbSNP:551163406
477 477 -, g dbSNP:758414053
477 477 a, c dbSNP:754969438
479 479 g, t dbSNP:765748549
486 486 a, t dbSNP:755352873
520 520 c, g, t dbSNP:121912708
523 523 g, t dbSNP:763780569
537 537 a, g dbSNP:762428797
542 542 c, t dbSNP:749853326
546 546 c, t dbSNP:149228266
548 548 a, g dbSNP:765099324
550 550 c, g dbSNP:759418993
551 551 a, c, g, t dbSNP:549279821
554 554 c, t dbSNP:145329188
556 556 c, t dbSNP:370624118
565 565 a, g dbSNP:117295656
578 578 a, g dbSNP:778997049
586 586 a, g dbSNP:760527001
607 607 a, c dbSNP:772989605
609 609 c, t dbSNP:772201739
615 615 c, g dbSNP:199653162
621 621 g, t dbSNP:774328460
624 624 a, g dbSNP:768899130
627 627 g, t dbSNP:749358074
634 634 c, g, t dbSNP:551773096
642 642 c, t dbSNP:375095250
677 677 a, g dbSNP:781569684
678 678 g, t dbSNP:758016489
683 683 c, t dbSNP:747873042
686 686 c, g dbSNP:375491094
687 687 a, g dbSNP:754537923
694 694 a, g dbSNP:753339039
711 711 a, t dbSNP:200447936
714 714 g, t dbSNP:756081030
717 717 c, t dbSNP:750418342
719 719 a, g dbSNP:767336581
720 720 c, t dbSNP:757135576
721 721 c, g dbSNP:140102105
722 722 a, c dbSNP:764417585
724 724 -, ctgattgagca dbSNP:765119568
728 728 c, t dbSNP:763217060
730 730 a, g dbSNP:775743077
742 742 c, g dbSNP:765445537
744 744 c, t dbSNP:369859575
745 745 a, g, t dbSNP:61757685
751 751 c, t dbSNP:771335275
767 767 c, t dbSNP:376917645
769 769 a, g dbSNP:773503933
776 776 a, g dbSNP:372660425
780 780 c, t dbSNP:748904145
781 781 c, t dbSNP:779652673
784 784 a, g dbSNP:769398736
788 788 c, t dbSNP:121912709
789 789 a, g dbSNP:745357569
794 794 a, g dbSNP:781259686
799 799 g, t dbSNP:555896752
807 807 c, t dbSNP:369380330
811 811 a, g dbSNP:777670051
813 813 c, t dbSNP:758236544
814 814 a, g dbSNP:753014428
815 815 c, t dbSNP:200433565
819 819 a, g dbSNP:765542228
822 822 c, g dbSNP:759724393
831 831 c, t dbSNP:537260194
838 838 c, t dbSNP:753791407
848 848 c, g dbSNP:202084501
856 856 a, g dbSNP:777829351
857 857 c, t dbSNP:140827978
858 858 c, t dbSNP:758324700
865 865 c, t dbSNP:752533662
867 867 c, t dbSNP:57902950
871 871 a, g dbSNP:755093525
874 874 a, g dbSNP:201832111
880 880 a, g dbSNP:752824129
891 891 a, t dbSNP:756247675
898 898 a, g dbSNP:750500704
909 909 a, g dbSNP:768018240
912 912 c, t dbSNP:757704473
913 913 a, c dbSNP:751944211
922 922 a, c dbSNP:140701322
940 940 a, t dbSNP:763353456
962 962 c, t dbSNP:776202861
972 972 a, g dbSNP:772877760
973 973 a, g dbSNP:767172222
994 994 a, t dbSNP:761387197
999 999 a, g dbSNP:774216010
1016 1016 a, g dbSNP:768638552
1021 1021 c, g dbSNP:369271104
1024 1024 -, g dbSNP:746295168
1026 1026 a, c, g, t dbSNP:201948406
1031 1031 a, g dbSNP:746052220
1034 1034 a, g dbSNP:781369461
1035 1035 c, g dbSNP:771054683
1044 1044 c, g dbSNP:747107627
1045 1045 a, g dbSNP:778146305
1050 1050 a, g dbSNP:150623275
1067 1067 g, t dbSNP:756879600
1074 1074 c, g dbSNP:751053781
1076 1076 g, t dbSNP:763620908
1091 1091 a, c dbSNP:762340782
1094 1094 a, t dbSNP:121912711
1099 1099 a, g dbSNP:765153843
1106 1106 c, g dbSNP:141775154
1115 1115 a, g dbSNP:767632811
1122 1122 c, t dbSNP:202069068
1132 1132 c, g dbSNP:774519989
1139 1139 -, c dbSNP:778003597
1139 1139 c, t dbSNP:572990686
1142 1142 c, t dbSNP:148052962
1147 1147 c, g dbSNP:775830338
1152 1152 c, t dbSNP:114516357
1153 1153 a, g dbSNP:746212816
1154 1154 c, t dbSNP:3189320
1157 1157 c, t dbSNP:777483675
1179 1179 a, g dbSNP:761295869
1187 1187 c, g dbSNP:543182575
1190 1190 c, t dbSNP:144625212
1191 1191 a, g dbSNP:563675719
1192 1192 a, g dbSNP:111319259
1196 1196 a, g dbSNP:754449549
1210 1210 c, t dbSNP:181287032
1211 1211 a, g dbSNP:771975420
1212 1212 c, t dbSNP:761523599
1217 1217 c, g dbSNP:774148433
1224 1224 c, g, t dbSNP:121912710
1232 1232 c, t dbSNP:780233639
1233 1233 a, g dbSNP:572831296
1234 1234 a, g dbSNP:2306618
1237 1237 a, g dbSNP:201792544
1243 1243 a, t dbSNP:757726867
1244 1244 c, g dbSNP:751898560
1257 1257 c, t dbSNP:778236831
1258 1258 a, g dbSNP:758810390
1262 1262 c, t dbSNP:753598402
1263 1263 a, g dbSNP:587780850
1267 1267 a, g dbSNP:760266177
1272 1272 a, g dbSNP:749889093
1275 1275 c, t dbSNP:767375552
1276 1276 a, g dbSNP:150305320
1277 1277 c, t dbSNP:774126237
1279 1279 c, g dbSNP:121912707
1284 1284 a, t dbSNP:762723665
1286 1286 c, t dbSNP:775759943
1287 1287 c, t dbSNP:375030056
1292 1292 c, t dbSNP:151107837
1293 1293 a, g dbSNP:538504116
1296 1296 g, t dbSNP:372127110
1297 1297 c, t dbSNP:548996847
1301 1301 -, at dbSNP:753671880
1301 1301 a, g dbSNP:747597620
1303 1303 a, g dbSNP:778125731
1305 1305 c, g dbSNP:142975776
1315 1315 a, c dbSNP:12514417
1320 1320 c, t dbSNP:755365818
1329 1329 a, g dbSNP:745584430
1335 1335 c, t dbSNP:780696540
1349 1349 a, g dbSNP:200299784
1350 1350 a, g dbSNP:200980969
1356 1356 a, c dbSNP:756859037
1360 1360 g, t dbSNP:750971835
1369 1369 a, c dbSNP:764036426
1375 1375 a, g, t dbSNP:186558364
1384 1384 a, g dbSNP:375090702
1396 1396 a, g dbSNP:113609617
1405 1405 c, t dbSNP:752523070
1406 1406 a, g dbSNP:147940248
1407 1407 c, g dbSNP:759234889
1411 1411 -, g dbSNP:772766995
1434 1434 -, tg dbSNP:770492145
1442 1442 c, t dbSNP:144701796
1457 1457 c, t dbSNP:766645306
1459 1459 -, a dbSNP:760092559
1460 1460 -, caa dbSNP:777187854
1461 1461 a, g dbSNP:372488916
1464 1464 c, t dbSNP:750640713
1477 1477 g, t dbSNP:767756650
1481 1481 g, t dbSNP:763418390
1486 1486 c, t dbSNP:202104680
1490 1490 g, t dbSNP:751635252
1491 1491 a, g dbSNP:764688935
1506 1506 c, t dbSNP:565405031
1513 1513 c, g dbSNP:556400964
1515 1515 c, t dbSNP:765576421
1520 1520 a, c, g dbSNP:80049945
1521 1521 a, g dbSNP:540451615
1534 1534 a, g dbSNP:771651423
1547 1547 a, g dbSNP:200102503
1550 1550 c, t dbSNP:773694788
1553 1553 a, c, g dbSNP:749231711
1556 1556 a, g dbSNP:561343926
1561 1561 a, g dbSNP:755930241
1564 1564 a, t dbSNP:745592760
1567 1567 a, g dbSNP:61757684
1570 1570 a, g dbSNP:765681480
1572 1572 a, c dbSNP:556737742
1574 1574 a, g dbSNP:754312564
1578 1578 c, t dbSNP:538884744
1579 1579 a, g dbSNP:761013423
1597 1597 a, g dbSNP:749839120
1597 1597 -, g dbSNP:387906574
1608 1608 c, g dbSNP:763737676
1609 1609 a, g dbSNP:762383899
1610 1610 a, g dbSNP:775017806
1617 1617 a, g dbSNP:769887865
1625 1625 a, g dbSNP:759591318
1626 1626 g, t dbSNP:776690396
1649 1649 c, t dbSNP:559710313
1653 1653 a, g dbSNP:374780587
1662 1662 c, g dbSNP:371971136
1666 1666 g, t dbSNP:372788241
1667 1667 g, t dbSNP:777869197
1685 1685 -, gaaa dbSNP:765576367
1688 1688 a, g dbSNP:2775
1719 1719 g, t dbSNP:553327175
1760 1760 c, g dbSNP:374361465
1769 1769 a, g dbSNP:187827993
1820 1820 a, g dbSNP:549472131
1832 1832 a, c dbSNP:143317618
1873 1873 a, t dbSNP:542748598
1922 1922 c, t dbSNP:775192146
1939 1939 g, t dbSNP:570223278
1945 1945 a, g dbSNP:55923017
2015 2015 a, t dbSNP:781309579
2023 2023 c, t dbSNP:112493228
2024 2024 a, g dbSNP:533678440
2029 2029 -, g dbSNP:556732113
2037 2037 c, t dbSNP:574931385
2051 2051 c, t dbSNP:779037755
2075 2075 a, g dbSNP:182676227
2080 2080 a, g dbSNP:191020661
2116 2116 a, c dbSNP:755220331
2168 2168 c, t dbSNP:1060856
2208 2208 c, g dbSNP:780328831
2261 2261 a, g dbSNP:372065850
2265 2265 a, c dbSNP:367884177
2296 2296 c, t dbSNP:7447380
2310 2310 c, t dbSNP:139905907
2317 2317 c, t dbSNP:544919864
2319 2319 c, t dbSNP:750743133
2346 2346 c, t dbSNP:1060857
2351 2351 a, g dbSNP:1138001
2427 2427 c, g dbSNP:1807
2438 2438 a, g dbSNP:1138005
2518 2518 -, gag dbSNP:543290589
2592 2592 c, t dbSNP:574036505
2600 2600 -, a dbSNP:60217601
2600 2600 a, c dbSNP:74892068
2620 2620 -, aa, aaa dbSNP:368894310
2656 2656 c, g dbSNP:370883463
2673 2673 a, g dbSNP:555808054
2678 2678 c, t dbSNP:111675585
2679 2679 a, g dbSNP:541187121
2728 2728 a, g dbSNP:1483780
2732 2732 g, t dbSNP:80345302
2744 2744 a, c dbSNP:769291143
2759 2759 c, g dbSNP:539682277
2772 2772 c, g dbSNP:146010837
2776 2776 a, c, t dbSNP:181404590
2823 2823 c, t dbSNP:144106312
2829 2829 a, g dbSNP:555172968
2838 2838 c, g dbSNP:372984832
2844 2844 c, t dbSNP:565083629
2902 2902 a, g dbSNP:548608589
2908 2908 a, g dbSNP:190996922
2930 2930 g, t dbSNP:778898407
2955 2955 c, t dbSNP:768755329
2961 2961 a, g dbSNP:139186397
2988 2988 a, t dbSNP:115645125
3005 3005 c, t dbSNP:532956497
3060 3060 a, g dbSNP:559504053
3061 3061 c, t dbSNP:541286622
3066 3066 a, g dbSNP:114580465
3068 3068 a, g dbSNP:576450678
3074 3074 a, g dbSNP:555797762
3143 3143 a, g dbSNP:780351820
3165 3165 c, t dbSNP:555863580
3202 3202 a, g dbSNP:543869348
3292 3292 a, g dbSNP:78029541
3313 3313 a, c dbSNP:557939339
3315 3315 a, t dbSNP:62947162
3322 3322 g, t dbSNP:200532010
3322 3322 -, t dbSNP:5871218
3335 3335 a, c dbSNP:756259873
3350 3350 c, t dbSNP:185960737
3359 3359 a, g dbSNP:566092091
3361 3361 a, t dbSNP:744720
3368 3368 at, tg dbSNP:386692155
3368 3368 a, t dbSNP:744721
3369 3369 -, g dbSNP:199550747
3369 3369 g, t dbSNP:744722
3408 3408 a, g dbSNP:533650761
3424 3424 c, t dbSNP:744723
3447 3447 a, g dbSNP:565927910
3456 3456 a, c dbSNP:763990036
3485 3485 c, t dbSNP:755847753
3504 3504 c, g dbSNP:189465791
3507 3507 a, c dbSNP:569655770
3558 3558 a, g dbSNP:551144920
3587 3587 a, g dbSNP:752477837
3692 3692 c, g dbSNP:553257829
3696 3696 a, c dbSNP:767359075
3706 3706 a, c dbSNP:759427220
3741 3741 c, t dbSNP:375841477
3746 3746 a, g dbSNP:115168957
3750 3750 c, t dbSNP:765274850
3767 3767 a, g dbSNP:752082866
3767 3767 -, g dbSNP:369180172
3810 3810 c, t dbSNP:559274917
3835 3835 g, t dbSNP:762058139
3874 3874 a, t dbSNP:76249070
3887 3887 c, g dbSNP:184630563
3908 3908 c, t dbSNP:764956560
3927 3927 -, t dbSNP:113950002
3934 3934 c, t dbSNP:561998848
3951 3951 a, g dbSNP:543756785
3967 3967 a, g dbSNP:538064274
4001 4001 c, t dbSNP:538927271
4007 4007 a, g dbSNP:116566135
4029 4029 a, c dbSNP:776633516
4039 4039 a, g dbSNP:545933526
4043 4043 c, t dbSNP:114575585
4084 4084 -, t dbSNP:200155555
4112 4112 c, t dbSNP:768166252
4116 4116 c, t dbSNP:769126957
4119 4119 a, g dbSNP:7715516
4126 4126 a, g dbSNP:370442664
4132 4132 a, g dbSNP:76363408
4159 4159 c, g dbSNP:574774962
4169 4169 c, g dbSNP:556404419
4189 4189 -, gc dbSNP:771970643
4195 4195 c, t dbSNP:114287342
4223 4223 a, g dbSNP:74415886
4285 4285 c, t dbSNP:749387811
4287 4287 -, c dbSNP:201421709
4317 4317 c, t dbSNP:368844061
4342 4342 a, g dbSNP:775421792
4384 4384 a, g dbSNP:181028716
4403 4403 a, g dbSNP:148309568
4408 4408 c, g dbSNP:189486979
4418 4418 -, t dbSNP:11395324
4419 4419 -, t dbSNP:59667289
4436 4436 c, t dbSNP:77525381
4438 4438 -, c dbSNP:780063692
4439 4439 -, c dbSNP:370255749
4462 4462 a, g dbSNP:145424881
4504 4504 -, aa dbSNP:542701107
4511 4511 c, t dbSNP:547600980
4517 4517 c, g dbSNP:184098590
4526 4526 c, t dbSNP:746329980
4534 4534 a, t dbSNP:192950824
4549 4549 a, g dbSNP:370866834
4605 4605 c, t dbSNP:550051176
4606 4606 -, t dbSNP:397760043
4606 4606 c, t dbSNP:369855064
4617 4617 -, t dbSNP:5871217
4624 4624 a, g dbSNP:57369925
4642 4642 c, t dbSNP:2035471
4656 4656 a, g dbSNP:756798087
4727 4727 a, g dbSNP:564310704
4730 4730 a, g dbSNP:546222411
4733 4733 c, t dbSNP:749036709
4744 4744 a, g dbSNP:572425402

Target ORF information:

RefSeq Version NM_001202404
Organism Homo sapiens (human)
Definition Homo sapiens aldehyde dehydrogenase 7 family, member A1 (ALDH7A1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001202404

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGGTTCTC CCGGGCGGGG GGCGGGGCTC TATTTCAGCA GCTCTCAGGG CCTTGGGCTC 
ATCCCGAGTC CCGGGCTCAG TATGTGGCGC CTTCCTCGCG CGCTGTGTGT GCACGCTGCA
AAGACCAGCA AGCTCTCTGG ACCTTGGAGC AGGCCTGCCG CCTTCATGTC CACTCTCCTC
ATCAATCAGC CCCAGTATGC GTGGCTGAAA GAGCTGGGGC TCCGCGAGGA AAACGAGGGC
GTGTATAATG GAAGCTGGGG AGGCCGGGGA GAGGTTATTA CGACCTATTG CCCTGCTAAC
AACGAGCCAA TAGCAAGAGT CCGACAGGCC AGTGTGGCAG ACTATGAAGA AACTGTAAAG
AAAGCAAGAG AAGCATGGAA AATCTGGGCA GATATTCCTG CTCCAAAACG AGGAGAAATA
GTAAGACAGA TTGGCGATGC CTTGCGGGAG AAGATCCAAG TACTAGGAAG CTTGGTGTCT
TTGGAGATGG GGAAAATCTT AGTGGAAGGT GTGGGTGAAG TTCAGGAGTA TGTGGATATC
TGTGACTATG CTGTTGGTTT ATCAAGGATG ATTGGAGGAC CTATCTTGCC TTCTGAAAGA
TCTGGCCATG CACTGATTGA GCAGTGGAAT CCCGTAGGCC TGGTTGGAAT CATCACGGCA
TTCAATTTCC CTGTGGCAGT GTATGGTTGG AACAACGCCA TCGCCATGAT CTGTGGAAAT
GTCTGCCTCT GGAAAGGAGC TCCAACCACT TCCCTCATTA GTGTGGCTGT CACAAAGATA
ATAGCCAAGG TTCTGGAGGA CAACAAGCTG CCTGGTGCAA TTTGTTCCTT GACTTGTGGT
GGAGCAGATA TTGGCACAGC AATGGCCAAA GATGAACGAG TGAACCTGCT GTCCTTCACT
GGGAGCACTC AGGTGGGAAA ACAGGTGGGC CTGATGGTGC AGGAGAGGTT TGGGAGAAGT
CTGTTGGAAC TTGGAGGAAA CAATGCCATT ATTGCCTTTG AAGATGCAGA CCTCAGCTTA
GTTGTTCCAT CAGCTCTCTT CGCTGCTGTG GGAACAGCTG GCCAGAGGTG TACCACTGCG
AGGCGACTGG TTATGGATCG CCCTGGAAAT TATGTAGAAC CGACAATTGT GACAGGTCTT
GGCCACGATG CGTCCATTGC ACACACAGAG ACTTTTGCTC CGATTCTCTA TGTCTTTAAA
TTCAAGAATG AAGAAGAGGT CTTTGCATGG AATAATGAAG TAAAACAGGG ACTTTCAAGT
AGCATCTTTA CCAAAGATCT GGGCAGAATC TTTCGCTGGC TTGGACCTAA AGGATCAGAC
TGTGGCATTG TAAATGTCAA CATTCCAACA AGTGGGGCTG AGATTGGAGG TGCCTTTGGA
GGAGAAAAGC ACACTGGTGG TGGCAGGGAG TCTGGCAGTG ATGCCTGGAA ACAGTACATG
AGAAGGTCTA CTTGTACTAT CAACTACAGT AAAGACCTTC CTCTGGCCCA AGGAATCAAG
TTTCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.