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PAX9 cDNA ORF clone, Homo sapiens (human)

Gene Symbol PAX9
Entrez Gene ID 5083
Full Name paired box 9
Synonyms STHAG3
General protein information
Preferred Names
paired box protein Pax-9
Names
paired box protein Pax-9
paired domain gene 9
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

14

14q13.3

Summary This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 9 gene is unknown but it may involve development of stratified squamous epithelia as well as various organs and skeletal elements. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

167416

Disorder Html: Tooth agenesis, selective, 3, 604625 (3)

mRNA and Protein(s)

mRNA Protein Name
NM_006194 NP_006185 paired box protein Pax-9


Homo sapiens (human) PAX9 NP_006185.1
Pan troglodytes (chimpanzee) PAX9 XP_001143345.2
Macaca mulatta (Rhesus monkey) PAX9 XP_002805071.1
Canis lupus familiaris (dog) PAX9 XP_005623393.1
Bos taurus (cattle) PAX9 NP_001179298.1
Mus musculus (house mouse) Pax9 NP_035171.1
Rattus norvegicus (Norway rat) Pax9 NP_001034628.1
Gallus gallus (chicken) PAX9 XP_004941978.1
Danio rerio (zebrafish) pax9 NP_571373.1
Xenopus (Silurana) tropicalis (western clawed frog) pax9 XP_002935394.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PAX9 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PAX9 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu22291
NM_006194 Homo sapiens paired box 9 (PAX9), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
Starting from $49.50
$99.00

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu22291
Clone ID Related Accession (Same CDS sequence) NM_006194
Accession Version NM_006194.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1026bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product paired box protein Pax-9
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB233208.1, DB196800.1, BC001159.1, AL079303.3 and AB248958.1. This sequence is a reference standard in the RefSeqGene project. On or before Aug 31, 2013 this sequence version replaced gi:530403885, gi:154350239. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AB248958.1, BC001159.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGAGCCAG CCTTCGGGGA GGTGAACCAG CTGGGAGGAG TGTTCGTGAA CGGGAGGCCG 
CTGCCCAACG CCATCCGGCT TCGCATCGTG GAACTGGCCC AACTGGGCAT CCGACCGTGT
GACATCAGCC GCCAGCTACG GGTCTCGCAC GGCTGCGTCA GCAAGATCCT GGCGCGATAC
AACGAGACGG GCTCGATCTT GCCAGGAGCC ATCGGGGGCA GCAAGCCCCG GGTCACTACC
CCCACCGTGG TGAAACACAT CCGGACCTAC AAGCAGAGAG ACCCCGGCAT CTTCGCCTGG
GAGATCCGGG ACCGCCTGCT GGCGGACGGC GTGTGCGACA AGTACAATGT GCCCTCCGTG
AGCTCCATCA GCCGCATTCT GCGCAACAAG ATCGGCAACT TGGCCCAGCA GGGTCATTAC
GACTCATACA AGCAGCACCA GCCGACGCCG CAGCCAGCGC TGCCCTACAA CCACATCTAC
TCGTACCCCA GCCCTATCAC GGCGGCGGCC GCCAAGGTGC CCACGCCACC CGGGGTGCCT
GCCATCCCCG GTTCGGTGGC CATGCCGCGC ACCTGGCCCT CCTCGCACTC CGTCACCGAC
ATCCTGGGCA TCCGCTCCAT CACCGACCAA GTGAGCGACA GCTCCCCCTA CCACAGCCCC
AAGGTGGAGG AGTGGAGCAG CCTGGGCCGC AACAACTTCC CCGCCGCCGC CCCGCACGCG
GTGAACGGGT TGGAGAAGGG AGCCCTGGAG CAGGAAGCCA AGTACGGTCA GGCACCAAAT
GGTCTCCCAG CTGTGGGCAG TTTTGTGTCA GCATCCAGCA TGGCTCCTTA CCCTACCCCA
GCCCAAGTGT CGCCTTACAT GACCTACAGT GCTGCTCCTT CTGGTTATGT TGCTGGACAT
GGGTGGCAAC ATGCTGGGGG CACCTCATTG TCTCCCCACA ACTGTGACAT TCCGGCATCG
CTGGCGTTCA AGGGAATGCA GGCAGCCAGA GAAGGTAGTC ATTCTGTCAC GGCTTCCGCG
CTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_006185.1
CDS727..1752
Misc Feature(1)658..660(+)
Misc Feature(2)742..1119(+)
Misc Feature(3)751..1110(+)
Misc Feature(4)802..1110(+)
Misc Feature(5)1228..1293(+)
Exon (1)1..333
Gene:PAX9
Gene Synonym:
Exon (2)334..730
Gene:PAX9
Gene Synonym:
Exon (3)731..1357
Gene:PAX9
Gene Synonym:
Exon (4)1358..1497
Gene:PAX9
Gene Synonym:
Exon (5)1498..3107
Gene:PAX9
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_006194
Organism Homo sapiens (human)
Definition Homo sapiens paired box 9 (PAX9), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_006194

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGAGCCAG CCTTCGGGGA GGTGAACCAG CTGGGAGGAG TGTTCGTGAA CGGGAGGCCG 
CTGCCCAACG CCATCCGGCT TCGCATCGTG GAACTGGCCC AACTGGGCAT CCGACCGTGT
GACATCAGCC GCCAGCTACG GGTCTCGCAC GGCTGCGTCA GCAAGATCCT GGCGCGATAC
AACGAGACGG GCTCGATCTT GCCAGGAGCC ATCGGGGGCA GCAAGCCCCG GGTCACTACC
CCCACCGTGG TGAAACACAT CCGGACCTAC AAGCAGAGAG ACCCCGGCAT CTTCGCCTGG
GAGATCCGGG ACCGCCTGCT GGCGGACGGC GTGTGCGACA AGTACAATGT GCCCTCCGTG
AGCTCCATCA GCCGCATTCT GCGCAACAAG ATCGGCAACT TGGCCCAGCA GGGTCATTAC
GACTCATACA AGCAGCACCA GCCGACGCCG CAGCCAGCGC TGCCCTACAA CCACATCTAC
TCGTACCCCA GCCCTATCAC GGCGGCGGCC GCCAAGGTGC CCACGCCACC CGGGGTGCCT
GCCATCCCCG GTTCGGTGGC CATGCCGCGC ACCTGGCCCT CCTCGCACTC CGTCACCGAC
ATCCTGGGCA TCCGCTCCAT CACCGACCAA GTGAGCGACA GCTCCCCCTA CCACAGCCCC
AAGGTGGAGG AGTGGAGCAG CCTGGGCCGC AACAACTTCC CCGCCGCCGC CCCGCACGCG
GTGAACGGGT TGGAGAAGGG AGCCCTGGAG CAGGAAGCCA AGTACGGTCA GGCACCAAAT
GGTCTCCCAG CTGTGGGCAG TTTTGTGTCA GCATCCAGCA TGGCTCCTTA CCCTACCCCA
GCCCAAGTGT CGCCTTACAT GACCTACAGT GCTGCTCCTT CTGGTTATGT TGCTGGACAT
GGGTGGCAAC ATGCTGGGGG CACCTCATTG TCTCCCCACA ACTGTGACAT TCCGGCATCG
CTGGCGTTCA AGGGAATGCA GGCAGCCAGA GAAGGTAGTC ATTCTGTCAC GGCTTCCGCG
CTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

SNPs and interaction analyses of IRF6, MSX1 and PAX9 genes in patients with nonsyndromic cleft lip with or without palate
Mol Med Rep 8 (4), 1228-1234 (2013)
Song T, Wu D, Wang Y, Li H, Yin N and Zhao Z.


book

Large-scale genotyping identifies 41 new loci associated with breast cancer risk
Nat. Genet. 45 (4), 353-361 (2013)
Michailidou K, Hall P, Gonzalez-Neira A, Ghoussaini M, Dennis J, Milne RL, Schmidt MK, Chang-Claude J, Bojesen SE, Bolla MK, Wang Q, Dicks E, Lee A, Turnbull C, Rahman N, Fletcher O, Peto J, Gibson L, Dos Santos Silva I, Nevanlinna H, Muranen TA, Aittomaki K, Blomqvist C, Czene K, Irwanto A, Liu J, Waisfisz Q, Meijers-Heijboer H, Adank M, van der Luijt RB, Hein R, Dahmen N, Beckman L, Meindl A, Schmutzler RK, Muller-Myhsok B, Lichtner P, Hopper JL, Southey MC, Makalic E, Schmidt DF, Uitterlinden AG, Hofman A, Hunter DJ, Chanock SJ, Vincent D, Bacot F, Tessier DC, Canisius S, Wessels LF, Haiman CA, Shah M, Luben R, Brown J, Luccarini C, Schoof N, Humphreys K, Li J, Nordestgaard BG, Nielsen SF, Flyger H, Couch FJ, Wang X, Vachon C, Stevens KN, Lambrechts D, Moisse M, Paridaens R, Christiaens MR, Rudolph A, Nickels S, Flesch-Janys D, Johnson N, Aitken Z, Aaltonen K, Heikkinen T, Broeks A, Veer LJ, van der Schoot CE, Guenel P, Truong T, Laurent-Puig P, Menegaux F, Marme F, Schneeweiss A, Sohn C, Burwinkel B, Zamora MP, Perez JI, Pita G, Alonso MR, Cox A, Brock IW, Cross SS, Reed MW, Sawyer EJ, Tomlinson I, Kerin MJ, Miller N, Henderson BE, Schumacher F, Le Marchand L, Andrulis IL, Knight JA, Glendon G, Mulligan AM, Lindblom A, Margolin S, Hooning MJ, Hollestelle A, van den Ouweland AM, Jager A, Bui QM, Stone J, Dite GS, Apicella C, Tsimiklis H, Giles GG, Severi G, Baglietto L, Fasching PA, Haeberle L, Ekici AB, Beckmann MW, Brenner H, Muller H, Arndt V, Stegmaier C, Swerdlow A, Ashworth A, Orr N, Jones M, Figueroa J, Lissowska J, Brinton L, Goldberg MS, Labreche F, Dumont M, Winqvist R, Pylkas K, Jukkola-Vuorinen A, Grip M, Brauch H, Hamann U, Bruning T, Radice P, Peterlongo P, Manoukian S, Bonanni B, Devilee P, Tollenaar RA, Seynaeve C, van Asperen CJ, Jakubowska A, Lubinski J, Jaworska K, Durda K, Mannermaa A, Kataja V, Kosma VM, Hartikainen JM, Bogdanova NV, Antonenkova NN, Dork T, Kristensen VN, Anton-Culver H, Slager S, Toland AE, Edge S, Fostira F, Kang D, Yoo KY, Noh DY, Matsuo K, Ito H, Iwata H, Sueta A, Wu AH, Tseng CC, Van Den Berg D, Stram DO, Shu XO, Lu W, Gao YT, Cai H, Teo SH, Yip CH, Phuah SY, Cornes BK, Hartman M, Miao H, Lim WY, Sng JH, Muir K, Lophatananon A, Stewart-Brown S, Siriwanarangsan P, Shen CY, Hsiung CN, Wu PE, Ding SL, Sangrajrang S, Gaborieau V, Brennan P, McKay J, Blot WJ, Signorello LB, Cai Q, Zheng W, Deming-Halverson S, Shrubsole M, Long J, Simard J, Garcia-Closas M, Pharoah PD, Chenevix-Trench G, Dunning AM, Benitez J and Easton DF.


book

PAX9 polymorphism and susceptibility to sporadic non-syndromic severe anodontia: a case-control study in southwest China
J Appl Oral Sci 21 (3), 256-264 (2013)
Wang J, Xu Y, Chen J, Wang F, Huang R, Wu S, Shu L, Qiu J, Yang Z, Xue J, Wang R, Zhao J and Lai W.


book

Association between PAX9 single-nucleotide polymorphisms and nonsyndromic cleft lip with or without cleft palate
J Craniofac Surg 23 (5), 1262-1266 (2012)
Lee JK, Park JW, Kim YH and Baek SH.


book

Novel PAX9 and COL1A2 missense mutations causing tooth agenesis and OI/DGI without skeletal abnormalities
PLoS ONE 7 (12), E51533 (2012)
Wang SK, Chan HC, Makovey I, Simmer JP and Hu JC.


book

The novel polymorphic variants within the paired box of the PAX9 gene are associated with selective tooth agenesis
Folia Histochem. Cytobiol. 39 (2), 111-112 (2001)
Kobielak A, Kobielak K, Wisniewski AS, Mostowska A, Biedziak B and Trzeciak WH.


book

Evolutionary conservation of gene structures of the Pax1/9 gene family
Biochim. Biophys. Acta 1492 (2-3), 517-521 (2000)
Hetzer-Egger C, Schorpp M and Boehm T.


book

Mutation of PAX9 is associated with oligodontia
Nat. Genet. 24 (1), 18-19 (2000)
Stockton DW, Das P, Goldenberg M, D'Souza RN and Patel PI.


book

Isolation of the Pax9 cDNA from adult human esophagus
Mamm. Genome 8 (1), 62-64 (1997)
Peters H, Schuster G, Neubuser A, Richter T, Hofler H and Balling R.


book

Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9
Nat. Genet. 3 (4), 292-298 (1993)
Stapleton P, Weith A, Urbanek P, Kozmik Z and Busslinger M.


 
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