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GP6 glycoprotein VI (platelet) [Homo sapiens (human)]

Gene Symbol GP6
Entrez Gene ID 51206
Full Name glycoprotein VI (platelet)
Synonyms BDPLT11, GPIV, GPVI
General protein information
Preferred Names
platelet glycoprotein VI
Names
platelet glycoprotein VI
glycoprotein 6
platelet collagen receptor
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q13.4

Summary This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]. lac of sum
Disorder MIM:

605546

Disorder Html:





The following GP6 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GP6 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu20368 NM_001083899 Homo sapiens glycoprotein VI (platelet) (GP6), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 Quote Price
OHu20989 NM_001256017 Homo sapiens glycoprotein VI (platelet) (GP6), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199
OHu21878 NM_016363 Homo sapiens glycoprotein VI (platelet) (GP6), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $379

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu20368
Accession Version NM_001083899.2
Sequence Information ORF Nucleotide Sequence (Length: 1863bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product platelet glycoprotein VI isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB043821.1 and AC011476.8. On Dec 6, 2013 this sequence version replaced gi:143770740. Summary: This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB043821.1, BC069485.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
ATGTCTCCAT CCCCGACCGC CCTCTTCTGT CTTGGGCTGT GTCTGGGGCG TGTGCCAGCG 
CAGAGTGGAC CGCTCCCCAA GCCCTCCCTC CAGGCTCTGC CCAGCTCCCT GGTGCCCCTG
GAGAAGCCAG TGACCCTCCG GTGCCAGGGA CCTCCGGGCG TGGACCTGTA CCGCCTGGAG
AAGCTGAGTT CCAGCAGGTA CCAGGATCAG GCAGTCCTCT TCATCCCGGC CATGAAGAGA
AGTCTGGCTG GACGCTACCG CTGCTCCTAC CAGAACGGAA GCCTCTGGTC CCTGCCCAGC
GACCAGCTGG AGCTCGTTGC CACGGGAGTT TTTGCCAAAC CCTCGCTCTC AGCCCAGCCC
GGCCCGGCGG TGTCGTCAGG AGGGGACGTA ACCCTACAGT GTCAGACTCG GTATGGCTTT
GACCAATTTG CTCTGTACAA GGAAGGGGAC CCTGCGCCCT ACAAGAATCC CGAGAGATGG
TACAGGGCTA GTTTTCCCAT CATCACGGTG ACCGCCGCCC ACAGCGGAAC CTACCGATGC
TACAGCTTCT CCAGCAGGGA CCCATACCTG TGGTCAGCCC CCAGCGACCC CCTGGAGCTT
GTGGTCACAG GAACCTCTGT GACCCCCAGC CGGTTACCAA CAGAACCACC TTCCCCGGTA
GCAGAATTCT CAGAAGCCAC CGCTGAACTG ACCGTCTCAT TCACAAACGA AGTCTTCACA
ACTGAGACTT CTAGGAGTAT CACCGCCAGT CCAAAGGAGT CAGACTCTCC AGCTGGTGAG
TCCTGCCCGC CAGTACTACA CCAAGGGCAA CCTGGTCCGG ATATGCCTCG GGGCTGTGAT
CCTAATAATC CTGGCGGGGT TTCTGGCAGA GGACTGGCAC AGCCGGAGGA AGCGCCTGCG
GCACAGGGGC AGGGCTGTGC AGAGGCCGCT TCCGCCCCTC CCGCCCCTCC CGCTGACCCG
GAAATCAAAC GGGGGTCAGG ATGGAGGCCG ACAGGATGTT CACAGCCGCG GGTTATGTTC
ATGACCGCTG AACCCCAGGC ACGGTCGTAT CCAAGGGAGG GATCATGGCA TGGGAGGCGA
CTCAAAGACT GGCGTGTGTG GAGCGTGGAA GCAGGAGGGC AGAGGCTACA GCTGTGGAAA
CGAGGCCATG CTGCCTCCTC CTGGTGTTCC ATCAGGGAGC CGTTCGGCCA GTGTCTGTCT
GTCTGTCTGC CTCTCTGTCT GAGGGCACCC TCCATTTGGG ATGGAAGGAA TCTGTGGAGA
CCCCATCCTC CTCCCTGCAC ACTGTGGATG ACATGGTACC CTGGCTGGAC CACATACTGG
CCTCTTTCTT CAACCTCTCT AATATGGGCT CCAGACGGAT CTCTAAGGTT CCCAGCTCTC
AGGGTTGACT CTGTTCCATC CTCTGTGCAA AATCCTCCCG TGCTTCCCTT TGGCCCTCTG
TGCTCTTGTC TGGTTTTCCC CAGAAACTCT CACCCTCACT CCATCTCCCA CTGCGGTCTA
ACAAATCTCC TTTCGTCTCT CAGAACGGGT CTTGCAGGCA GTTTGGGTAT GTCATTCATT
TTCCTTAGTG TAAAACTAGC ACGTTGCCCG CTTCCCTTCA CATTAGAAAA CAAGATCAGC
CTGTGCAACA TGGTGAAACC TCATCTCTAC CAACAAAACA AAAAAACACA AAAATTAGCC
AGGTGTGGTG GTGCATCCCT ATACTCCCAG CAACTCAGGG GGCTGAGGTG GGAGAATGGC
TTGAGCCTGG GAGGCAGAGG TTGCAGTGAG CTGAGATCAC ACCACTGCAC TCTAGCTCGG
GTGACGAAGC CTGACTTTGT CTCAAAAAAT ACAGGGATGA ATATGTCAAT TACCCTGATT
TGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001077368.2
CDS29..1891
Misc Feature(1)20..22(+)
Misc Feature(2)104..352(+)
Misc Feature(3)206..316(+)
Misc Feature(4)365..634(+)
Exon (1)1..62
Gene:GP6
Gene Synonym:
Exon (2)63..95
Gene:GP6
Gene Synonym:
Exon (3)96..353
Gene:GP6
Gene Synonym:
Exon (4)354..638
Gene:GP6
Gene Synonym:
Exon (5)639..692
Gene:GP6
Gene Synonym:
Exon (6)693..752
Gene:GP6
Gene Synonym:
Exon (7)753..807
Gene:GP6
Gene Synonym:
Exon (8)808..2268
Gene:GP6
Gene Synonym:
Translation
Position Chain Variation Link
2 2 c, t dbSNP:187629313
16 16 a, g dbSNP:777366918
18 18 a, g dbSNP:376612602
21 21 c, g dbSNP:568620558
24 24 g, t dbSNP:752582598
29 29 a, g dbSNP:764762153
39 39 c, g dbSNP:754527697
42 42 c, t dbSNP:371674665
43 43 a, g dbSNP:28385642
46 46 c, t dbSNP:199807828
47 47 a, g dbSNP:569446020
48 48 c, t dbSNP:764304178
52 52 c, t dbSNP:763537328
55 55 c, t dbSNP:776100510
67 67 c, g dbSNP:776785166
76 76 c, g dbSNP:770869085
77 77 c, t dbSNP:748269983
78 78 a, g dbSNP:773349443
87 87 a, c, t dbSNP:369642453
88 88 a, g, t dbSNP:201025246
90 90 a, g dbSNP:778679076
96 96 g, t dbSNP:761244764
97 97 a, g dbSNP:750477581
99 99 c, t dbSNP:767523302
100 100 a, g dbSNP:368522136
102 102 a, t dbSNP:773976878
105 105 c, t dbSNP:774514319
108 108 a, g dbSNP:764268085
110 110 c, t dbSNP:201283598
113 113 g, t dbSNP:775341524
114 114 a, c dbSNP:769686181
125 125 c, t dbSNP:28385643
130 130 c, t dbSNP:745762025
132 132 c, g dbSNP:200313847
134 134 c, t dbSNP:770526790
139 139 a, g dbSNP:746487471
145 145 a, c dbSNP:777620820
149 149 c, g dbSNP:758112169
153 153 a, g dbSNP:749686530
162 162 c, t dbSNP:780402836
165 165 c, t dbSNP:113219102
167 167 c, t dbSNP:756588702
168 168 a, g dbSNP:750889036
176 176 a, g dbSNP:767613010
177 177 a, g dbSNP:757364878
182 182 c, t dbSNP:751615170
183 183 c, t dbSNP:764355964
184 184 a, g dbSNP:763231845
187 187 c, t dbSNP:775151408
200 200 c, t dbSNP:199588110
201 201 a, g, t dbSNP:561370230
202 202 c, t dbSNP:776751773
211 211 a, g, t dbSNP:200403102
219 219 c, t dbSNP:772847163
223 223 c, t dbSNP:771631715
226 226 a, g dbSNP:146751606
234 234 a, t dbSNP:780301940
247 247 c, t dbSNP:28385644
250 250 c, t dbSNP:746184218
253 253 c, t dbSNP:189503167
256 256 a, g dbSNP:757745719
265 265 a, g dbSNP:28385645
270 270 a, g dbSNP:200424845
277 277 c, g, t dbSNP:559176407
279 279 a, g dbSNP:758571097
281 281 c, t dbSNP:752925351
288 288 a, g, t dbSNP:759426349
289 289 c, t dbSNP:554527184
300 300 a, g dbSNP:766494410
304 304 c, g, t dbSNP:545004274
305 305 a, g dbSNP:771558250
311 311 c, t dbSNP:761400559
313 313 c, t dbSNP:774089152
319 319 c, t dbSNP:370941526
328 328 c, t dbSNP:768168959
329 329 a, g dbSNP:572860909
331 331 c, t dbSNP:781531121
332 332 c, t dbSNP:771430932
335 335 c, g, t dbSNP:28969501
343 343 c, t dbSNP:374599974
344 344 a, g dbSNP:575231122
346 346 c, t dbSNP:567724105
352 352 a, g dbSNP:752698122
353 353 a, g dbSNP:779255434
354 354 a, c, g dbSNP:41311975
362 362 a, g dbSNP:771378058
363 363 a, c dbSNP:775164410
367 367 a, t dbSNP:764848572
372 372 c, g, t dbSNP:773447414
373 373 a, g dbSNP:772641061
374 374 c, g dbSNP:748548999
384 384 -, agccc dbSNP:760074158
388 388 -, agccc dbSNP:777169435
388 388 c, t dbSNP:375405887
389 389 a, g dbSNP:372032713
391 391 c, g dbSNP:79133006
392 392 c, t dbSNP:749343738
394 394 a, g, t dbSNP:756389201
408 408 g, t dbSNP:745739794
413 413 g, t dbSNP:536418941
414 414 a, t dbSNP:375205262
418 418 a, t dbSNP:115934645
426 426 a, g dbSNP:763987657
429 429 c, g dbSNP:757953891
431 431 c, t dbSNP:752191942
432 432 a, c, t dbSNP:764938362
433 433 g, t dbSNP:550808731
437 437 c, t dbSNP:759124753
438 438 a, g dbSNP:773642386
447 447 c, t dbSNP:374450055
448 448 c, t dbSNP:762417766
453 453 a, t dbSNP:371526523
459 459 c, t dbSNP:774756684
460 460 c, t dbSNP:769260812
466 466 c, g dbSNP:749433788
475 475 a, g dbSNP:201166741
478 478 c, t dbSNP:571307915
483 483 c, t dbSNP:746018547
484 484 a, g dbSNP:781062868
489 489 a, c dbSNP:756962244
490 490 c, g dbSNP:746798268
497 497 c, t dbSNP:777746272
499 499 c, t dbSNP:758328364
500 500 a, g, t dbSNP:778339783
503 503 a, t dbSNP:754684731
505 505 a, g dbSNP:753396840
508 508 a, g dbSNP:766027583
511 511 c, t dbSNP:762130319
512 512 -, c dbSNP:771165550
512 512 a, c, t dbSNP:892090
514 514 c, g dbSNP:763485474
515 515 g, t dbSNP:775726835
516 516 a, c dbSNP:769947136
519 519 c, g dbSNP:759834481
523 523 c, t dbSNP:892089
525 525 c, t dbSNP:771170249
529 529 c, t dbSNP:746844654
533 533 a, g dbSNP:777476310
535 535 a, g dbSNP:5030705
541 541 c, t dbSNP:748027211
542 542 a, g dbSNP:778421895
544 544 c, t dbSNP:754483221
552 552 a, g, t dbSNP:387906919
553 553 c, t dbSNP:367907292
554 554 a, g dbSNP:755790003
564 564 a, g dbSNP:751979972
567 567 c, g dbSNP:764497463
581 581 a, g dbSNP:369568059
583 583 c, g dbSNP:546902436
591 591 c, g dbSNP:753216495
593 593 c, t dbSNP:765744190
595 595 a, c dbSNP:201652983
596 596 c, g dbSNP:41300084
600 600 a, g dbSNP:776766695
601 601 c, g dbSNP:41301959
603 603 c, g, t dbSNP:534339924
604 604 a, c, g dbSNP:1654425
606 606 c, t dbSNP:370855777
612 612 a, g dbSNP:200525940
613 613 c, g dbSNP:768628583
614 614 a, g, t dbSNP:779552982
617 617 a, c dbSNP:755737487
618 618 a, c, g dbSNP:778314910
628 628 g, t dbSNP:758874083
629 629 a, g dbSNP:753098085
658 658 c, t dbSNP:781041470
659 659 c, g, t dbSNP:368555743
660 660 a, g, t dbSNP:373154193
671 671 a, g, t dbSNP:555734027
674 674 -, cc dbSNP:771675174
674 674 c, g dbSNP:766761398
682 682 c, t dbSNP:539172883
683 683 c, t dbSNP:1613662
684 684 a, c dbSNP:767798856
685 685 g, t dbSNP:557946250
710 710 c, g dbSNP:781194651
715 715 a, g dbSNP:199576708
718 718 a, g dbSNP:751766995
721 721 c, t dbSNP:764192104
728 728 a, t dbSNP:762855744
730 730 c, t dbSNP:752421887
736 736 -, cgaa dbSNP:754929349
737 737 a, c, g dbSNP:1654416
737 737 -, g dbSNP:747661380
739 739 -, a dbSNP:778336022
745 745 a, c dbSNP:776301634
747 747 c, g dbSNP:201917182
750 750 c, t dbSNP:760070554
760 760 c, t dbSNP:760286317
773 773 a, g dbSNP:2304167
776 776 a, c dbSNP:202044825
777 777 c, g dbSNP:761318901
790 790 -, a dbSNP:764228426
790 790 a, g dbSNP:775857911
791 791 c, g dbSNP:770106401
796 796 -, tc dbSNP:763180314
797 797 c, g dbSNP:746202039
799 799 a, g dbSNP:373073778
804 804 a, g dbSNP:771329127
810 810 c, g dbSNP:533241802
813 813 g, t dbSNP:563944012
816 816 c, t dbSNP:540599440
817 817 a, g dbSNP:771474578
831 831 a, t dbSNP:749210453
834 834 a, g dbSNP:747424824
847 847 a, g dbSNP:372829679
848 848 c, g dbSNP:772083213
854 854 c, g, t dbSNP:779332945
857 857 c, t dbSNP:190904614
858 858 a, c, g dbSNP:779660245
860 860 a, g dbSNP:60843302
861 861 a, g dbSNP:750290180
867 867 a, g dbSNP:767460935
875 875 a, t dbSNP:201436629
878 878 a, c dbSNP:751058450
879 879 c, t dbSNP:763803376
883 883 c, t dbSNP:762526564
884 884 a, g dbSNP:754222737
893 893 a, g dbSNP:766612048
902 902 c, t dbSNP:761067320
903 903 a, t dbSNP:773639794
907 907 a, g dbSNP:772616628
908 908 c, g dbSNP:762049176
912 912 c, t dbSNP:201753264
913 913 a, g dbSNP:201997410
919 919 a, c dbSNP:749476604
922 922 a, g dbSNP:779935541
924 924 -, c dbSNP:752850718
927 927 c, t dbSNP:371817808
928 928 a, c, g dbSNP:781050416
930 930 c, t dbSNP:757183693
933 933 a, g dbSNP:751074784
950 950 a, g dbSNP:777208826
953 953 a, g dbSNP:537357993
955 955 c, t dbSNP:752332158
956 956 a, g dbSNP:373346261
957 957 c, t dbSNP:534709050
959 959 c, t dbSNP:750792954
961 961 c, t dbSNP:200151153
962 962 a, g dbSNP:762347897
968 968 c, g dbSNP:2304166
969 969 a, c dbSNP:768821288
970 970 c, t dbSNP:200431311
973 973 -, ccctcccgc dbSNP:760157972
973 973 a, c dbSNP:775626235
974 974 -, cctcccgct dbSNP:771380662
974 974 c, t dbSNP:770045316
977 977 c, t dbSNP:745718736
979 979 c, t dbSNP:780973296
980 980 a, g dbSNP:770868762
982 982 -, cccgca dbSNP:760940207
982 982 a, t dbSNP:1654413
987 987 c, t dbSNP:746907519
988 988 a, g dbSNP:777656189
995 995 a, t dbSNP:757950138
996 996 a, c dbSNP:1671152
998 998 a, c, t dbSNP:754590544
999 999 a, g dbSNP:80348265
1001 1001 c, g dbSNP:200948100
1007 1007 a, g dbSNP:757874715
1009 1009 a, g dbSNP:752155931
1017 1017 c, t dbSNP:368858591
1018 1018 a, g dbSNP:374509474
1020 1020 c, g dbSNP:775635724
1022 1022 a, g dbSNP:549916040
1023 1023 a, g dbSNP:267605686
1025 1025 g, t dbSNP:759748523
1026 1026 g, t dbSNP:776313503
1029 1029 c, t dbSNP:770751968
1031 1031 c, g dbSNP:746782553
1035 1035 c, t dbSNP:201413568
1036 1036 a, g dbSNP:767901432
1037 1037 c, t dbSNP:747612828
1039 1039 a, g dbSNP:778426724
1048 1048 c, g dbSNP:754606143
1051 1051 a, g dbSNP:201603906
1054 1054 c, t dbSNP:540637093
1055 1055 a, g, t dbSNP:759751882
1061 1061 c, g dbSNP:764765255
1063 1063 c, t dbSNP:527330221
1067 1067 a, g dbSNP:561323272
1070 1070 c, t dbSNP:765312634
1071 1071 a, g dbSNP:186103270
1073 1073 c, t dbSNP:776886080
1074 1074 c, t dbSNP:200019444
1075 1075 a, g dbSNP:557292489
1078 1078 g, t dbSNP:772920810
1082 1082 a, c dbSNP:772006921
1084 1084 g, t dbSNP:375643910
1085 1085 g, t dbSNP:748067631
1093 1093 a, t dbSNP:773762259
1102 1102 g, t dbSNP:768256234
1107 1107 a, g, t dbSNP:779914827
1111 1111 a, c dbSNP:755827734
1116 1116 a, g dbSNP:747382737
1119 1119 g, t dbSNP:778225188
1121 1121 c, t dbSNP:373596955
1122 1122 a, c, g dbSNP:370477228
1124 1124 -, g dbSNP:773558453
1127 1127 c, t dbSNP:755141586
1130 1130 a, t dbSNP:753910818
1133 1133 a, g, t dbSNP:377522937
1141 1141 a, t dbSNP:750237644
1148 1148 c, t dbSNP:767299494
1151 1151 a, c dbSNP:761484721
1153 1153 g, t dbSNP:774398889
1157 1157 c, t dbSNP:751635237
1158 1158 a, c, g dbSNP:775074233
1159 1159 a, g dbSNP:769584360
1169 1169 c, t dbSNP:745470892
1170 1170 a, c, g dbSNP:182940784
1177 1177 c, t dbSNP:748445118
1179 1179 c, g dbSNP:779540658
1186 1186 c, t dbSNP:755373331
1188 1188 -, cct dbSNP:771635825
1188 1188 c, g, t dbSNP:199813278
1189 1189 c, t dbSNP:780055487
1194 1194 a, g dbSNP:756358091
1196 1196 g, t dbSNP:750681822
1210 1210 a, g dbSNP:767614700
1213 1213 c, t dbSNP:761729129
1214 1214 g, t dbSNP:751311313
1219 1219 -, tgtc dbSNP:59110861
1219 1219 c, g dbSNP:200940260
1222 1222 -, ttgt dbSNP:747748721
1224 1224 c, t dbSNP:762927953
1226 1226 a, c, t dbSNP:769390004
1227 1227 a, c dbSNP:759087504
1230 1230 -, tctgtctg dbSNP:768134535
1232 1232 c, t dbSNP:776401390
1233 1233 -, tctg dbSNP:773724485
1234 1234 -, tctg dbSNP:775950031
1234 1234 c, t dbSNP:766715406
1237 1237 -, tctg, tctgtctg dbSNP:138680589
1241 1241 c, t dbSNP:748550203
1242 1242 c, t dbSNP:779088536
1253 1253 a, g dbSNP:769169673
1260 1260 c, t dbSNP:749752950
1268 1268 a, g dbSNP:370026589
1270 1270 c, t dbSNP:780505285
1272 1272 c, g dbSNP:150807394
1277 1277 a, c dbSNP:566107894
1280 1280 c, g dbSNP:745937021
1293 1293 a, g dbSNP:781548792
1303 1303 c, g dbSNP:555783596
1315 1315 a, g dbSNP:74697203
1317 1317 a, t dbSNP:763747397
1322 1322 c, t dbSNP:758443526
1332 1332 c, g dbSNP:752723824
1341 1341 c, g dbSNP:570109671
1350 1350 c, t dbSNP:759181602
1357 1357 c, t dbSNP:775936716
1361 1361 a, g dbSNP:766068188
1365 1365 c, g dbSNP:760193172
1369 1369 a, c dbSNP:774805420
1377 1377 c, g, t dbSNP:201940503
1384 1384 c, t dbSNP:776037769
1385 1385 a, g dbSNP:770284082
1400 1400 c, t dbSNP:745968195
1408 1408 c, t dbSNP:533111925
1420 1420 c, t dbSNP:369436148
1444 1444 c, t dbSNP:747159406
1447 1447 c, t dbSNP:1671151
1453 1453 -, t dbSNP:780995686
1456 1456 c, t dbSNP:377575412
1462 1462 c, t dbSNP:776592723
1463 1463 a, c dbSNP:765268240
1464 1464 c, t dbSNP:754904771
1468 1468 a, g dbSNP:753409870
1474 1474 -, tt dbSNP:758728587
1474 1474 c, t dbSNP:765762954
1486 1486 c, t dbSNP:760198171
1487 1487 c, t dbSNP:141737256
1488 1488 c, t dbSNP:768546634
1495 1495 c, t dbSNP:199561271
1511 1511 a, g dbSNP:763379117
1515 1515 c, t dbSNP:775768250
1517 1517 c, t dbSNP:368961812
1522 1522 c, t dbSNP:770304194
1523 1523 a, g dbSNP:41275822
1524 1524 a, g dbSNP:776805197
1537 1537 -, cct dbSNP:765453546
1537 1537 -, tc dbSNP:752938783
1537 1537 c, t dbSNP:770957240
1543 1543 a, c, g dbSNP:146318651
1551 1551 c, g dbSNP:772352178
1553 1553 a, g dbSNP:142053457
1554 1554 c, t dbSNP:778801507
1555 1555 a, c, g dbSNP:753756120
1557 1557 a, g dbSNP:780015649
1558 1558 a, t dbSNP:755635088
1559 1559 c, g dbSNP:200399196
1573 1573 a, g dbSNP:374982514
1578 1578 c, g, t dbSNP:200566792
1580 1580 c, t dbSNP:753087191
1583 1583 c, t dbSNP:375130495
1584 1584 g, t dbSNP:372569183
1593 1593 c, t dbSNP:368350811
1595 1595 a, c dbSNP:777054385
1596 1596 a, g dbSNP:768061284
1606 1606 a, t dbSNP:771458181
1610 1610 c, t dbSNP:760673543
1614 1614 g, t dbSNP:374590810
1617 1617 c, t dbSNP:772444957
1618 1618 a, g dbSNP:748340999
1623 1623 c, t dbSNP:771846036
1627 1627 c, g dbSNP:372175929
1633 1633 a, g dbSNP:768381545
1642 1642 g, t dbSNP:749092940
1643 1643 a, g dbSNP:779925828
1649 1649 c, t dbSNP:578145430
1651 1651 a, g dbSNP:368531531
1653 1653 g, t dbSNP:780636331
1656 1656 a, g dbSNP:756934246
1658 1658 a, g dbSNP:751253075
1672 1672 c, t dbSNP:763715619
1674 1674 a, t dbSNP:759878316
1675 1675 c, t dbSNP:754162124
1677 1677 a, g dbSNP:766808148
1685 1685 a, g dbSNP:201681535
1687 1687 a, c, g dbSNP:772313424
1690 1690 -, aaaaa dbSNP:759672977
1694 1694 -, a dbSNP:754459187
1710 1710 c, g dbSNP:761959070
1715 1715 g, t dbSNP:774769403
1720 1720 g, t dbSNP:768916446
1732 1732 c, g dbSNP:749043915
1742 1742 c, t dbSNP:775300532
1744 1744 c, t dbSNP:541786453
1745 1745 a, g dbSNP:1654412
1749 1749 g, t dbSNP:781077689
1750 1750 -, g dbSNP:766797825
1752 1752 a, t dbSNP:756811244
1753 1753 a, g, t dbSNP:777356988
1754 1754 a, g dbSNP:758008926
1755 1755 a, g dbSNP:10418074
1760 1760 g, t dbSNP:766725027
1765 1765 g, t dbSNP:756516167
1770 1770 c, t dbSNP:751011830
1773 1773 g, t dbSNP:372168591
1780 1780 -, tccc dbSNP:761185718
1793 1793 a, g dbSNP:190384471
1810 1810 c, t dbSNP:774503825
1817 1817 a, c dbSNP:115459014
1833 1833 c, t dbSNP:2886416
1834 1834 a, g dbSNP:775183932
1844 1844 c, t dbSNP:1671150
1847 1847 a, g dbSNP:745640729
1848 1848 c, t dbSNP:570669348
1849 1849 a, c dbSNP:770852322
1853 1853 a, g dbSNP:746533320
1854 1854 a, c dbSNP:777286436
1864 1864 g, t dbSNP:758016611
1900 1900 c, t dbSNP:747874978
1901 1901 a, g dbSNP:778403744
1902 1902 c, g, t dbSNP:138796044
1910 1910 -, atgtac dbSNP:761491834
1915 1915 a, c dbSNP:76129219
1923 1923 c, t dbSNP:567986876
1925 1925 a, g dbSNP:547798735
1940 1940 a, t dbSNP:186874802
1952 1952 g, t dbSNP:562322946
1953 1953 a, c dbSNP:10417981
1977 1977 -, aaataa dbSNP:770364130
1986 1986 a, g dbSNP:532098985
1993 1993 c, t dbSNP:752994413
2004 2004 c, t dbSNP:10417943
2031 2031 a, g dbSNP:541590036
2049 2049 a, g dbSNP:572797096
2064 2064 a, t dbSNP:562331603
2071 2071 a, g dbSNP:542141082
2078 2078 c, t dbSNP:769718229
2122 2122 a, g dbSNP:564914757
2133 2133 a, c dbSNP:143249922
2139 2139 c, t dbSNP:149570465
2163 2163 a, g dbSNP:780731263
2197 2197 c, g dbSNP:750698868
2217 2217 c, t dbSNP:565777020
2226 2226 c, t dbSNP:41275820
2248 2248 a, g dbSNP:533705783

Target ORF information:

RefSeq Version NM_001083899
Organism Homo sapiens (human)
Definition Homo sapiens glycoprotein VI (platelet) (GP6), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001083899

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
ATGTCTCCAT CCCCGACCGC CCTCTTCTGT CTTGGGCTGT GTCTGGGGCG TGTGCCAGCG 
CAGAGTGGAC CGCTCCCCAA GCCCTCCCTC CAGGCTCTGC CCAGCTCCCT GGTGCCCCTG
GAGAAGCCAG TGACCCTCCG GTGCCAGGGA CCTCCGGGCG TGGACCTGTA CCGCCTGGAG
AAGCTGAGTT CCAGCAGGTA CCAGGATCAG GCAGTCCTCT TCATCCCGGC CATGAAGAGA
AGTCTGGCTG GACGCTACCG CTGCTCCTAC CAGAACGGAA GCCTCTGGTC CCTGCCCAGC
GACCAGCTGG AGCTCGTTGC CACGGGAGTT TTTGCCAAAC CCTCGCTCTC AGCCCAGCCC
GGCCCGGCGG TGTCGTCAGG AGGGGACGTA ACCCTACAGT GTCAGACTCG GTATGGCTTT
GACCAATTTG CTCTGTACAA GGAAGGGGAC CCTGCGCCCT ACAAGAATCC CGAGAGATGG
TACAGGGCTA GTTTTCCCAT CATCACGGTG ACCGCCGCCC ACAGCGGAAC CTACCGATGC
TACAGCTTCT CCAGCAGGGA CCCATACCTG TGGTCAGCCC CCAGCGACCC CCTGGAGCTT
GTGGTCACAG GAACCTCTGT GACCCCCAGC CGGTTACCAA CAGAACCACC TTCCCCGGTA
GCAGAATTCT CAGAAGCCAC CGCTGAACTG ACCGTCTCAT TCACAAACGA AGTCTTCACA
ACTGAGACTT CTAGGAGTAT CACCGCCAGT CCAAAGGAGT CAGACTCTCC AGCTGGTGAG
TCCTGCCCGC CAGTACTACA CCAAGGGCAA CCTGGTCCGG ATATGCCTCG GGGCTGTGAT
CCTAATAATC CTGGCGGGGT TTCTGGCAGA GGACTGGCAC AGCCGGAGGA AGCGCCTGCG
GCACAGGGGC AGGGCTGTGC AGAGGCCGCT TCCGCCCCTC CCGCCCCTCC CGCTGACCCG
GAAATCAAAC GGGGGTCAGG ATGGAGGCCG ACAGGATGTT CACAGCCGCG GGTTATGTTC
ATGACCGCTG AACCCCAGGC ACGGTCGTAT CCAAGGGAGG GATCATGGCA TGGGAGGCGA
CTCAAAGACT GGCGTGTGTG GAGCGTGGAA GCAGGAGGGC AGAGGCTACA GCTGTGGAAA
CGAGGCCATG CTGCCTCCTC CTGGTGTTCC ATCAGGGAGC CGTTCGGCCA GTGTCTGTCT
GTCTGTCTGC CTCTCTGTCT GAGGGCACCC TCCATTTGGG ATGGAAGGAA TCTGTGGAGA
CCCCATCCTC CTCCCTGCAC ACTGTGGATG ACATGGTACC CTGGCTGGAC CACATACTGG
CCTCTTTCTT CAACCTCTCT AATATGGGCT CCAGACGGAT CTCTAAGGTT CCCAGCTCTC
AGGGTTGACT CTGTTCCATC CTCTGTGCAA AATCCTCCCG TGCTTCCCTT TGGCCCTCTG
TGCTCTTGTC TGGTTTTCCC CAGAAACTCT CACCCTCACT CCATCTCCCA CTGCGGTCTA
ACAAATCTCC TTTCGTCTCT CAGAACGGGT CTTGCAGGCA GTTTGGGTAT GTCATTCATT
TTCCTTAGTG TAAAACTAGC ACGTTGCCCG CTTCCCTTCA CATTAGAAAA CAAGATCAGC
CTGTGCAACA TGGTGAAACC TCATCTCTAC CAACAAAACA AAAAAACACA AAAATTAGCC
AGGTGTGGTG GTGCATCCCT ATACTCCCAG CAACTCAGGG GGCTGAGGTG GGAGAATGGC
TTGAGCCTGG GAGGCAGAGG TTGCAGTGAG CTGAGATCAC ACCACTGCAC TCTAGCTCGG
GTGACGAAGC CTGACTTTGT CTCAAAAAAT ACAGGGATGA ATATGTCAAT TACCCTGATT
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20989
Accession Version NM_001256017.2
Sequence Information ORF Nucleotide Sequence (Length: 966bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product platelet glycoprotein VI isoform 3 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB043820.1 and AC011476.8. On Dec 6, 2013 this sequence version replaced gi:365192547. Summary: This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]. Transcript Variant: This variant (3) lacks an exon and uses an alternate splice site in the 3' coding region, compared to variant 1, that results in a frameshift. It encodes isoform 3 which has a shorter and distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB043820.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968968 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCTCCAT CCCCGACCGC CCTCTTCTGT CTTGGGCTGT GTCTGGGGCG TGTGCCAGCG 
CAGAGTGGAC CGCTCCCCAA GCCCTCCCTC CAGGCTCTGC CCAGCTCCCT GGTGCCCCTG
GAGAAGCCAG TGACCCTCCG GTGCCAGGGA CCTCCGGGCG TGGACCTGTA CCGCCTGGAG
AAGCTGAGTT CCAGCAGGTA CCAGGATCAG GCAGTCCTCT TCATCCCGGC CATGAAGAGA
AGTCTGGCTG GACGCTACCG CTGCTCCTAC CAGAACGGAA GCCTCTGGTC CCTGCCCAGC
GACCAGCTGG AGCTCGTTGC CACGGGAGTT TTTGCCAAAC CCTCGCTCTC AGCCCAGCCC
GGCCCGGCGG TGTCGTCAGG AGGGGACGTA ACCCTACAGT GTCAGACTCG GTATGGCTTT
GACCAATTTG CTCTGTACAA GGAAGGGGAC CCTGCGCCCT ACAAGAATCC CGAGAGATGG
TACAGGGCTA GTTTTCCCAT CATCACGGTG ACCGCCGCCC ACAGCGGAAC CTACCGATGC
TACAGCTTCT CCAGCAGGGA CCCATACCTG TGGTCAGCCC CCAGCGACCC CCTGGAGCTT
GTGGTCACAG AATTCTCAGA AGCCACCGCT GAACTGACCG TCTCATTCAC AAACGAAGTC
TTCACAACTG AGACTTCTAG GAGTATCACC GCCAGTCCAA AGGAGTCAGA CTCTCCAGCT
GGTCCTGCCC GCCAGTACTA CACCAAGGGC AACCTGGTCC GGATATGCCT CGGGGCTGTG
ATCCTAATAA TCCTGGCGGG GTTTCTGGCA GAGGACTGGC ACAGCCGGAG GAAGCGCCTG
CGGCACAGGG GCAGGGCTGT GCAGAGGCCG CTTCCGCCCC TCCCGCCCCT CCCGCTGACC
CGGAAATCAA ACGGGGGTCA GGATGGAGGC CGACAGGATG TTCACAGCCG CGGGTTATGT
TCATGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001242946.2
CDS29..994
Misc Feature(1)20..22(+)
Misc Feature(2)104..352(+)
Misc Feature(3)206..316(+)
Misc Feature(4)365..634(+)
Exon (1)1..62
Gene:GP6
Gene Synonym:
Exon (2)63..95
Gene:GP6
Gene Synonym:
Exon (3)96..353
Gene:GP6
Gene Synonym:
Exon (4)354..638
Gene:GP6
Gene Synonym:
Exon (5)639..698
Gene:GP6
Gene Synonym:
Exon (6)699..749
Gene:GP6
Gene Synonym:
Exon (7)750..2210
Gene:GP6
Gene Synonym:
Translation
Position Chain Variation Link
2 2 c, t dbSNP:187629313
16 16 a, g dbSNP:777366918
18 18 a, g dbSNP:376612602
21 21 c, g dbSNP:568620558
24 24 g, t dbSNP:752582598
29 29 a, g dbSNP:764762153
39 39 c, g dbSNP:754527697
42 42 c, t dbSNP:371674665
43 43 a, g dbSNP:28385642
46 46 c, t dbSNP:199807828
47 47 a, g dbSNP:569446020
48 48 c, t dbSNP:764304178
52 52 c, t dbSNP:763537328
55 55 c, t dbSNP:776100510
67 67 c, g dbSNP:776785166
76 76 c, g dbSNP:770869085
77 77 c, t dbSNP:748269983
78 78 a, g dbSNP:773349443
87 87 a, c, t dbSNP:369642453
88 88 a, g, t dbSNP:201025246
90 90 a, g dbSNP:778679076
96 96 g, t dbSNP:761244764
97 97 a, g dbSNP:750477581
99 99 c, t dbSNP:767523302
100 100 a, g dbSNP:368522136
102 102 a, t dbSNP:773976878
105 105 c, t dbSNP:774514319
108 108 a, g dbSNP:764268085
110 110 c, t dbSNP:201283598
113 113 g, t dbSNP:775341524
114 114 a, c dbSNP:769686181
125 125 c, t dbSNP:28385643
130 130 c, t dbSNP:745762025
132 132 c, g dbSNP:200313847
134 134 c, t dbSNP:770526790
139 139 a, g dbSNP:746487471
145 145 a, c dbSNP:777620820
149 149 c, g dbSNP:758112169
153 153 a, g dbSNP:749686530
162 162 c, t dbSNP:780402836
165 165 c, t dbSNP:113219102
167 167 c, t dbSNP:756588702
168 168 a, g dbSNP:750889036
176 176 a, g dbSNP:767613010
177 177 a, g dbSNP:757364878
182 182 c, t dbSNP:751615170
183 183 c, t dbSNP:764355964
184 184 a, g dbSNP:763231845
187 187 c, t dbSNP:775151408
200 200 c, t dbSNP:199588110
201 201 a, g, t dbSNP:561370230
202 202 c, t dbSNP:776751773
211 211 a, g, t dbSNP:200403102
219 219 c, t dbSNP:772847163
223 223 c, t dbSNP:771631715
226 226 a, g dbSNP:146751606
234 234 a, t dbSNP:780301940
247 247 c, t dbSNP:28385644
250 250 c, t dbSNP:746184218
253 253 c, t dbSNP:189503167
256 256 a, g dbSNP:757745719
265 265 a, g dbSNP:28385645
270 270 a, g dbSNP:200424845
277 277 c, g, t dbSNP:559176407
279 279 a, g dbSNP:758571097
281 281 c, t dbSNP:752925351
288 288 a, g, t dbSNP:759426349
289 289 c, t dbSNP:554527184
300 300 a, g dbSNP:766494410
304 304 c, g, t dbSNP:545004274
305 305 a, g dbSNP:771558250
311 311 c, t dbSNP:761400559
313 313 c, t dbSNP:774089152
319 319 c, t dbSNP:370941526
328 328 c, t dbSNP:768168959
329 329 a, g dbSNP:572860909
331 331 c, t dbSNP:781531121
332 332 c, t dbSNP:771430932
335 335 c, g, t dbSNP:28969501
343 343 c, t dbSNP:374599974
344 344 a, g dbSNP:575231122
346 346 c, t dbSNP:567724105
352 352 a, g dbSNP:752698122
353 353 a, g dbSNP:779255434
354 354 a, c, g dbSNP:41311975
362 362 a, g dbSNP:771378058
363 363 a, c dbSNP:775164410
367 367 a, t dbSNP:764848572
372 372 c, g, t dbSNP:773447414
373 373 a, g dbSNP:772641061
374 374 c, g dbSNP:748548999
384 384 -, agccc dbSNP:760074158
388 388 -, agccc dbSNP:777169435
388 388 c, t dbSNP:375405887
389 389 a, g dbSNP:372032713
391 391 c, g dbSNP:79133006
392 392 c, t dbSNP:749343738
394 394 a, g, t dbSNP:756389201
408 408 g, t dbSNP:745739794
413 413 g, t dbSNP:536418941
414 414 a, t dbSNP:375205262
418 418 a, t dbSNP:115934645
426 426 a, g dbSNP:763987657
429 429 c, g dbSNP:757953891
431 431 c, t dbSNP:752191942
432 432 a, c, t dbSNP:764938362
433 433 g, t dbSNP:550808731
437 437 c, t dbSNP:759124753
438 438 a, g dbSNP:773642386
447 447 c, t dbSNP:374450055
448 448 c, t dbSNP:762417766
453 453 a, t dbSNP:371526523
459 459 c, t dbSNP:774756684
460 460 c, t dbSNP:769260812
466 466 c, g dbSNP:749433788
475 475 a, g dbSNP:201166741
478 478 c, t dbSNP:571307915
483 483 c, t dbSNP:746018547
484 484 a, g dbSNP:781062868
489 489 a, c dbSNP:756962244
490 490 c, g dbSNP:746798268
497 497 c, t dbSNP:777746272
499 499 c, t dbSNP:758328364
500 500 a, g, t dbSNP:778339783
503 503 a, t dbSNP:754684731
505 505 a, g dbSNP:753396840
508 508 a, g dbSNP:766027583
511 511 c, t dbSNP:762130319
512 512 -, c dbSNP:771165550
512 512 a, c, t dbSNP:892090
514 514 c, g dbSNP:763485474
515 515 g, t dbSNP:775726835
516 516 a, c dbSNP:769947136
519 519 c, g dbSNP:759834481
523 523 c, t dbSNP:892089
525 525 c, t dbSNP:771170249
529 529 c, t dbSNP:746844654
533 533 a, g dbSNP:777476310
535 535 a, g dbSNP:5030705
541 541 c, t dbSNP:748027211
542 542 a, g dbSNP:778421895
544 544 c, t dbSNP:754483221
552 552 a, g, t dbSNP:387906919
553 553 c, t dbSNP:367907292
554 554 a, g dbSNP:755790003
564 564 a, g dbSNP:751979972
567 567 c, g dbSNP:764497463
581 581 a, g dbSNP:369568059
583 583 c, g dbSNP:546902436
591 591 c, g dbSNP:753216495
593 593 c, t dbSNP:765744190
595 595 a, c dbSNP:201652983
596 596 c, g dbSNP:41300084
600 600 a, g dbSNP:776766695
601 601 c, g dbSNP:41301959
603 603 c, g, t dbSNP:534339924
604 604 a, c, g dbSNP:1654425
606 606 c, t dbSNP:370855777
612 612 a, g dbSNP:200525940
613 613 c, g dbSNP:768628583
614 614 a, g, t dbSNP:779552982
617 617 a, c dbSNP:755737487
618 618 a, c, g dbSNP:778314910
628 628 g, t dbSNP:758874083
629 629 a, g dbSNP:753098085
656 656 c, g dbSNP:781194651
661 661 a, g dbSNP:199576708
664 664 a, g dbSNP:751766995
667 667 c, t dbSNP:764192104
674 674 a, t dbSNP:762855744
676 676 c, t dbSNP:752421887
682 682 -, cgaa dbSNP:754929349
683 683 a, c, g dbSNP:1654416
683 683 -, g dbSNP:747661380
685 685 -, a dbSNP:778336022
691 691 a, c dbSNP:776301634
693 693 c, g dbSNP:201917182
696 696 c, t dbSNP:760070554
706 706 c, t dbSNP:760286317
719 719 a, g dbSNP:2304167
722 722 a, c dbSNP:202044825
723 723 c, g dbSNP:761318901
736 736 -, a dbSNP:764228426
736 736 a, g dbSNP:775857911
737 737 c, g dbSNP:770106401
742 742 -, tc dbSNP:763180314
743 743 c, g dbSNP:746202039
745 745 a, g dbSNP:373073778
752 752 c, g dbSNP:533241802
755 755 g, t dbSNP:563944012
758 758 c, t dbSNP:540599440
759 759 a, g dbSNP:771474578
773 773 a, t dbSNP:749210453
776 776 a, g dbSNP:747424824
789 789 a, g dbSNP:372829679
790 790 c, g dbSNP:772083213
796 796 c, g, t dbSNP:779332945
799 799 c, t dbSNP:190904614
800 800 a, c, g dbSNP:779660245
802 802 a, g dbSNP:60843302
803 803 a, g dbSNP:750290180
809 809 a, g dbSNP:767460935
817 817 a, t dbSNP:201436629
820 820 a, c dbSNP:751058450
821 821 c, t dbSNP:763803376
825 825 c, t dbSNP:762526564
826 826 a, g dbSNP:754222737
835 835 a, g dbSNP:766612048
844 844 c, t dbSNP:761067320
845 845 a, t dbSNP:773639794
849 849 a, g dbSNP:772616628
850 850 c, g dbSNP:762049176
854 854 c, t dbSNP:201753264
855 855 a, g dbSNP:201997410
861 861 a, c dbSNP:749476604
864 864 a, g dbSNP:779935541
866 866 -, c dbSNP:752850718
869 869 c, t dbSNP:371817808
870 870 a, c, g dbSNP:781050416
872 872 c, t dbSNP:757183693
875 875 a, g dbSNP:751074784
892 892 a, g dbSNP:777208826
895 895 a, g dbSNP:537357993
897 897 c, t dbSNP:752332158
898 898 a, g dbSNP:373346261
899 899 c, t dbSNP:534709050
901 901 c, t dbSNP:750792954
903 903 c, t dbSNP:200151153
904 904 a, g dbSNP:762347897
910 910 c, g dbSNP:2304166
911 911 a, c dbSNP:768821288
912 912 c, t dbSNP:200431311
915 915 -, ccctcccgc dbSNP:760157972
915 915 a, c dbSNP:775626235
916 916 -, cctcccgct dbSNP:771380662
916 916 c, t dbSNP:770045316
919 919 c, t dbSNP:745718736
921 921 c, t dbSNP:780973296
922 922 a, g dbSNP:770868762
924 924 -, cccgca dbSNP:760940207
924 924 a, t dbSNP:1654413
929 929 c, t dbSNP:746907519
930 930 a, g dbSNP:777656189
937 937 a, t dbSNP:757950138
938 938 a, c dbSNP:1671152
940 940 a, c, t dbSNP:754590544
941 941 a, g dbSNP:80348265
943 943 c, g dbSNP:200948100
949 949 a, g dbSNP:757874715
951 951 a, g dbSNP:752155931
959 959 c, t dbSNP:368858591
960 960 a, g dbSNP:374509474
962 962 c, g dbSNP:775635724
964 964 a, g dbSNP:549916040
965 965 a, g dbSNP:267605686
967 967 g, t dbSNP:759748523
968 968 g, t dbSNP:776313503
971 971 c, t dbSNP:770751968
973 973 c, g dbSNP:746782553
977 977 c, t dbSNP:201413568
978 978 a, g dbSNP:767901432
979 979 c, t dbSNP:747612828
981 981 a, g dbSNP:778426724
990 990 c, g dbSNP:754606143
993 993 a, g dbSNP:201603906
996 996 c, t dbSNP:540637093
997 997 a, g, t dbSNP:759751882
1003 1003 c, g dbSNP:764765255
1005 1005 c, t dbSNP:527330221
1009 1009 a, g dbSNP:561323272
1012 1012 c, t dbSNP:765312634
1013 1013 a, g dbSNP:186103270
1015 1015 c, t dbSNP:776886080
1016 1016 c, t dbSNP:200019444
1017 1017 a, g dbSNP:557292489
1020 1020 g, t dbSNP:772920810
1024 1024 a, c dbSNP:772006921
1026 1026 g, t dbSNP:375643910
1027 1027 g, t dbSNP:748067631
1035 1035 a, t dbSNP:773762259
1044 1044 g, t dbSNP:768256234
1049 1049 a, g, t dbSNP:779914827
1053 1053 a, c dbSNP:755827734
1058 1058 a, g dbSNP:747382737
1061 1061 g, t dbSNP:778225188
1063 1063 c, t dbSNP:373596955
1064 1064 a, c, g dbSNP:370477228
1066 1066 -, g dbSNP:773558453
1069 1069 c, t dbSNP:755141586
1072 1072 a, t dbSNP:753910818
1075 1075 a, g, t dbSNP:377522937
1083 1083 a, t dbSNP:750237644
1090 1090 c, t dbSNP:767299494
1093 1093 a, c dbSNP:761484721
1095 1095 g, t dbSNP:774398889
1099 1099 c, t dbSNP:751635237
1100 1100 a, c, g dbSNP:775074233
1101 1101 a, g dbSNP:769584360
1111 1111 c, t dbSNP:745470892
1112 1112 a, c, g dbSNP:182940784
1119 1119 c, t dbSNP:748445118
1121 1121 c, g dbSNP:779540658
1128 1128 c, t dbSNP:755373331
1130 1130 -, cct dbSNP:771635825
1130 1130 c, g, t dbSNP:199813278
1131 1131 c, t dbSNP:780055487
1136 1136 a, g dbSNP:756358091
1138 1138 g, t dbSNP:750681822
1152 1152 a, g dbSNP:767614700
1155 1155 c, t dbSNP:761729129
1156 1156 g, t dbSNP:751311313
1161 1161 -, tgtc dbSNP:59110861
1161 1161 c, g dbSNP:200940260
1164 1164 -, ttgt dbSNP:747748721
1166 1166 c, t dbSNP:762927953
1168 1168 a, c, t dbSNP:769390004
1169 1169 a, c dbSNP:759087504
1172 1172 -, tctgtctg dbSNP:768134535
1174 1174 c, t dbSNP:776401390
1175 1175 -, tctg dbSNP:773724485
1176 1176 -, tctg dbSNP:775950031
1176 1176 c, t dbSNP:766715406
1179 1179 -, tctg, tctgtctg dbSNP:138680589
1183 1183 c, t dbSNP:748550203
1184 1184 c, t dbSNP:779088536
1195 1195 a, g dbSNP:769169673
1202 1202 c, t dbSNP:749752950
1210 1210 a, g dbSNP:370026589
1212 1212 c, t dbSNP:780505285
1214 1214 c, g dbSNP:150807394
1219 1219 a, c dbSNP:566107894
1222 1222 c, g dbSNP:745937021
1235 1235 a, g dbSNP:781548792
1245 1245 c, g dbSNP:555783596
1257 1257 a, g dbSNP:74697203
1259 1259 a, t dbSNP:763747397
1264 1264 c, t dbSNP:758443526
1274 1274 c, g dbSNP:752723824
1283 1283 c, g dbSNP:570109671
1292 1292 c, t dbSNP:759181602
1299 1299 c, t dbSNP:775936716
1303 1303 a, g dbSNP:766068188
1307 1307 c, g dbSNP:760193172
1311 1311 a, c dbSNP:774805420
1319 1319 c, g, t dbSNP:201940503
1326 1326 c, t dbSNP:776037769
1327 1327 a, g dbSNP:770284082
1342 1342 c, t dbSNP:745968195
1350 1350 c, t dbSNP:533111925
1362 1362 c, t dbSNP:369436148
1386 1386 c, t dbSNP:747159406
1389 1389 c, t dbSNP:1671151
1395 1395 -, t dbSNP:780995686
1398 1398 c, t dbSNP:377575412
1404 1404 c, t dbSNP:776592723
1405 1405 a, c dbSNP:765268240
1406 1406 c, t dbSNP:754904771
1410 1410 a, g dbSNP:753409870
1416 1416 -, tt dbSNP:758728587
1416 1416 c, t dbSNP:765762954
1428 1428 c, t dbSNP:760198171
1429 1429 c, t dbSNP:141737256
1430 1430 c, t dbSNP:768546634
1437 1437 c, t dbSNP:199561271
1453 1453 a, g dbSNP:763379117
1457 1457 c, t dbSNP:775768250
1459 1459 c, t dbSNP:368961812
1464 1464 c, t dbSNP:770304194
1465 1465 a, g dbSNP:41275822
1466 1466 a, g dbSNP:776805197
1479 1479 -, cct dbSNP:765453546
1479 1479 -, tc dbSNP:752938783
1479 1479 c, t dbSNP:770957240
1485 1485 a, c, g dbSNP:146318651
1493 1493 c, g dbSNP:772352178
1495 1495 a, g dbSNP:142053457
1496 1496 c, t dbSNP:778801507
1497 1497 a, c, g dbSNP:753756120
1499 1499 a, g dbSNP:780015649
1500 1500 a, t dbSNP:755635088
1501 1501 c, g dbSNP:200399196
1515 1515 a, g dbSNP:374982514
1520 1520 c, g, t dbSNP:200566792
1522 1522 c, t dbSNP:753087191
1525 1525 c, t dbSNP:375130495
1526 1526 g, t dbSNP:372569183
1535 1535 c, t dbSNP:368350811
1537 1537 a, c dbSNP:777054385
1538 1538 a, g dbSNP:768061284
1548 1548 a, t dbSNP:771458181
1552 1552 c, t dbSNP:760673543
1556 1556 g, t dbSNP:374590810
1559 1559 c, t dbSNP:772444957
1560 1560 a, g dbSNP:748340999
1565 1565 c, t dbSNP:771846036
1569 1569 c, g dbSNP:372175929
1575 1575 a, g dbSNP:768381545
1584 1584 g, t dbSNP:749092940
1585 1585 a, g dbSNP:779925828
1591 1591 c, t dbSNP:578145430
1593 1593 a, g dbSNP:368531531
1595 1595 g, t dbSNP:780636331
1598 1598 a, g dbSNP:756934246
1600 1600 a, g dbSNP:751253075
1614 1614 c, t dbSNP:763715619
1616 1616 a, t dbSNP:759878316
1617 1617 c, t dbSNP:754162124
1619 1619 a, g dbSNP:766808148
1627 1627 a, g dbSNP:201681535
1629 1629 a, c, g dbSNP:772313424
1632 1632 -, aaaaa dbSNP:759672977
1636 1636 -, a dbSNP:754459187
1652 1652 c, g dbSNP:761959070
1657 1657 g, t dbSNP:774769403
1662 1662 g, t dbSNP:768916446
1674 1674 c, g dbSNP:749043915
1684 1684 c, t dbSNP:775300532
1686 1686 c, t dbSNP:541786453
1687 1687 a, g dbSNP:1654412
1691 1691 g, t dbSNP:781077689
1692 1692 -, g dbSNP:766797825
1694 1694 a, t dbSNP:756811244
1695 1695 a, g, t dbSNP:777356988
1696 1696 a, g dbSNP:758008926
1697 1697 a, g dbSNP:10418074
1702 1702 g, t dbSNP:766725027
1707 1707 g, t dbSNP:756516167
1712 1712 c, t dbSNP:751011830
1715 1715 g, t dbSNP:372168591
1722 1722 -, tccc dbSNP:761185718
1735 1735 a, g dbSNP:190384471
1752 1752 c, t dbSNP:774503825
1759 1759 a, c dbSNP:115459014
1775 1775 c, t dbSNP:2886416
1776 1776 a, g dbSNP:775183932
1786 1786 c, t dbSNP:1671150
1789 1789 a, g dbSNP:745640729
1790 1790 c, t dbSNP:570669348
1791 1791 a, c dbSNP:770852322
1795 1795 a, g dbSNP:746533320
1796 1796 a, c dbSNP:777286436
1806 1806 g, t dbSNP:758016611
1842 1842 c, t dbSNP:747874978
1843 1843 a, g dbSNP:778403744
1844 1844 c, g, t dbSNP:138796044
1852 1852 -, atgtac dbSNP:761491834
1857 1857 a, c dbSNP:76129219
1865 1865 c, t dbSNP:567986876
1867 1867 a, g dbSNP:547798735
1882 1882 a, t dbSNP:186874802
1894 1894 g, t dbSNP:562322946
1895 1895 a, c dbSNP:10417981
1919 1919 -, aaataa dbSNP:770364130
1928 1928 a, g dbSNP:532098985
1935 1935 c, t dbSNP:752994413
1946 1946 c, t dbSNP:10417943
1973 1973 a, g dbSNP:541590036
1991 1991 a, g dbSNP:572797096
2006 2006 a, t dbSNP:562331603
2013 2013 a, g dbSNP:542141082
2020 2020 c, t dbSNP:769718229
2064 2064 a, g dbSNP:564914757
2075 2075 a, c dbSNP:143249922
2081 2081 c, t dbSNP:149570465
2105 2105 a, g dbSNP:780731263
2139 2139 c, g dbSNP:750698868
2159 2159 c, t dbSNP:565777020
2168 2168 c, t dbSNP:41275820
2190 2190 a, g dbSNP:533705783

Target ORF information:

RefSeq Version NM_001256017
Organism Homo sapiens (human)
Definition Homo sapiens glycoprotein VI (platelet) (GP6), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001256017

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCTCCAT CCCCGACCGC CCTCTTCTGT CTTGGGCTGT GTCTGGGGCG TGTGCCAGCG 
CAGAGTGGAC CGCTCCCCAA GCCCTCCCTC CAGGCTCTGC CCAGCTCCCT GGTGCCCCTG
GAGAAGCCAG TGACCCTCCG GTGCCAGGGA CCTCCGGGCG TGGACCTGTA CCGCCTGGAG
AAGCTGAGTT CCAGCAGGTA CCAGGATCAG GCAGTCCTCT TCATCCCGGC CATGAAGAGA
AGTCTGGCTG GACGCTACCG CTGCTCCTAC CAGAACGGAA GCCTCTGGTC CCTGCCCAGC
GACCAGCTGG AGCTCGTTGC CACGGGAGTT TTTGCCAAAC CCTCGCTCTC AGCCCAGCCC
GGCCCGGCGG TGTCGTCAGG AGGGGACGTA ACCCTACAGT GTCAGACTCG GTATGGCTTT
GACCAATTTG CTCTGTACAA GGAAGGGGAC CCTGCGCCCT ACAAGAATCC CGAGAGATGG
TACAGGGCTA GTTTTCCCAT CATCACGGTG ACCGCCGCCC ACAGCGGAAC CTACCGATGC
TACAGCTTCT CCAGCAGGGA CCCATACCTG TGGTCAGCCC CCAGCGACCC CCTGGAGCTT
GTGGTCACAG AATTCTCAGA AGCCACCGCT GAACTGACCG TCTCATTCAC AAACGAAGTC
TTCACAACTG AGACTTCTAG GAGTATCACC GCCAGTCCAA AGGAGTCAGA CTCTCCAGCT
GGTCCTGCCC GCCAGTACTA CACCAAGGGC AACCTGGTCC GGATATGCCT CGGGGCTGTG
ATCCTAATAA TCCTGGCGGG GTTTCTGGCA GAGGACTGGC ACAGCCGGAG GAAGCGCCTG
CGGCACAGGG GCAGGGCTGT GCAGAGGCCG CTTCCGCCCC TCCCGCCCCT CCCGCTGACC
CGGAAATCAA ACGGGGGTCA GGATGGAGGC CGACAGGATG TTCACAGCCG CGGGTTATGT
TCATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu21878
Accession Version NM_016363.5
Sequence Information ORF Nucleotide Sequence (Length: 1020bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product platelet glycoprotein VI isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB043819.1 and AC011476.8. On Dec 6, 2013 this sequence version replaced gi:143770754. Summary: This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]. Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1, that results in a frameshift. It encodes isoform 2 which has a shorter and distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB043819.1, BC104832.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCTCCAT CCCCGACCGC CCTCTTCTGT CTTGGGCTGT GTCTGGGGCG TGTGCCAGCG 
CAGAGTGGAC CGCTCCCCAA GCCCTCCCTC CAGGCTCTGC CCAGCTCCCT GGTGCCCCTG
GAGAAGCCAG TGACCCTCCG GTGCCAGGGA CCTCCGGGCG TGGACCTGTA CCGCCTGGAG
AAGCTGAGTT CCAGCAGGTA CCAGGATCAG GCAGTCCTCT TCATCCCGGC CATGAAGAGA
AGTCTGGCTG GACGCTACCG CTGCTCCTAC CAGAACGGAA GCCTCTGGTC CCTGCCCAGC
GACCAGCTGG AGCTCGTTGC CACGGGAGTT TTTGCCAAAC CCTCGCTCTC AGCCCAGCCC
GGCCCGGCGG TGTCGTCAGG AGGGGACGTA ACCCTACAGT GTCAGACTCG GTATGGCTTT
GACCAATTTG CTCTGTACAA GGAAGGGGAC CCTGCGCCCT ACAAGAATCC CGAGAGATGG
TACAGGGCTA GTTTTCCCAT CATCACGGTG ACCGCCGCCC ACAGCGGAAC CTACCGATGC
TACAGCTTCT CCAGCAGGGA CCCATACCTG TGGTCAGCCC CCAGCGACCC CCTGGAGCTT
GTGGTCACAG GAACCTCTGT GACCCCCAGC CGGTTACCAA CAGAACCACC TTCCCCGGTA
GCAGAATTCT CAGAAGCCAC CGCTGAACTG ACCGTCTCAT TCACAAACGA AGTCTTCACA
ACTGAGACTT CTAGGAGTAT CACCGCCAGT CCAAAGGAGT CAGACTCTCC AGCTGGTCCT
GCCCGCCAGT ACTACACCAA GGGCAACCTG GTCCGGATAT GCCTCGGGGC TGTGATCCTA
ATAATCCTGG CGGGGTTTCT GGCAGAGGAC TGGCACAGCC GGAGGAAGCG CCTGCGGCAC
AGGGGCAGGG CTGTGCAGAG GCCGCTTCCG CCCCTCCCGC CCCTCCCGCT GACCCGGAAA
TCAAACGGGG GTCAGGATGG AGGCCGACAG GATGTTCACA GCCGCGGGTT ATGTTCATGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_057447.5
CDS29..1048
Misc Feature(1)20..22(+)
Misc Feature(2)104..352(+)
Misc Feature(3)206..316(+)
Misc Feature(4)365..634(+)
Misc Feature(5)830..892(+)
Exon (1)1..62
Gene:GP6
Gene Synonym:
Exon (2)63..95
Gene:GP6
Gene Synonym:
Exon (3)96..353
Gene:GP6
Gene Synonym:
Exon (4)354..638
Gene:GP6
Gene Synonym:
Exon (5)639..692
Gene:GP6
Gene Synonym:
Exon (6)693..752
Gene:GP6
Gene Synonym:
Exon (7)753..803
Gene:GP6
Gene Synonym:
Exon (8)804..2264
Gene:GP6
Gene Synonym:
Translation
Position Chain Variation Link
2 2 c, t dbSNP:187629313
16 16 a, g dbSNP:777366918
18 18 a, g dbSNP:376612602
21 21 c, g dbSNP:568620558
24 24 g, t dbSNP:752582598
29 29 a, g dbSNP:764762153
39 39 c, g dbSNP:754527697
42 42 c, t dbSNP:371674665
43 43 a, g dbSNP:28385642
46 46 c, t dbSNP:199807828
47 47 a, g dbSNP:569446020
48 48 c, t dbSNP:764304178
52 52 c, t dbSNP:763537328
55 55 c, t dbSNP:776100510
67 67 c, g dbSNP:776785166
76 76 c, g dbSNP:770869085
77 77 c, t dbSNP:748269983
78 78 a, g dbSNP:773349443
87 87 a, c, t dbSNP:369642453
88 88 a, g, t dbSNP:201025246
90 90 a, g dbSNP:778679076
96 96 g, t dbSNP:761244764
97 97 a, g dbSNP:750477581
99 99 c, t dbSNP:767523302
100 100 a, g dbSNP:368522136
102 102 a, t dbSNP:773976878
105 105 c, t dbSNP:774514319
108 108 a, g dbSNP:764268085
110 110 c, t dbSNP:201283598
113 113 g, t dbSNP:775341524
114 114 a, c dbSNP:769686181
125 125 c, t dbSNP:28385643
130 130 c, t dbSNP:745762025
132 132 c, g dbSNP:200313847
134 134 c, t dbSNP:770526790
139 139 a, g dbSNP:746487471
145 145 a, c dbSNP:777620820
149 149 c, g dbSNP:758112169
153 153 a, g dbSNP:749686530
162 162 c, t dbSNP:780402836
165 165 c, t dbSNP:113219102
167 167 c, t dbSNP:756588702
168 168 a, g dbSNP:750889036
176 176 a, g dbSNP:767613010
177 177 a, g dbSNP:757364878
182 182 c, t dbSNP:751615170
183 183 c, t dbSNP:764355964
184 184 a, g dbSNP:763231845
187 187 c, t dbSNP:775151408
200 200 c, t dbSNP:199588110
201 201 a, g, t dbSNP:561370230
202 202 c, t dbSNP:776751773
211 211 a, g, t dbSNP:200403102
219 219 c, t dbSNP:772847163
223 223 c, t dbSNP:771631715
226 226 a, g dbSNP:146751606
234 234 a, t dbSNP:780301940
247 247 c, t dbSNP:28385644
250 250 c, t dbSNP:746184218
253 253 c, t dbSNP:189503167
256 256 a, g dbSNP:757745719
265 265 a, g dbSNP:28385645
270 270 a, g dbSNP:200424845
277 277 c, g, t dbSNP:559176407
279 279 a, g dbSNP:758571097
281 281 c, t dbSNP:752925351
288 288 a, g, t dbSNP:759426349
289 289 c, t dbSNP:554527184
300 300 a, g dbSNP:766494410
304 304 c, g, t dbSNP:545004274
305 305 a, g dbSNP:771558250
311 311 c, t dbSNP:761400559
313 313 c, t dbSNP:774089152
319 319 c, t dbSNP:370941526
328 328 c, t dbSNP:768168959
329 329 a, g dbSNP:572860909
331 331 c, t dbSNP:781531121
332 332 c, t dbSNP:771430932
335 335 c, g, t dbSNP:28969501
343 343 c, t dbSNP:374599974
344 344 a, g dbSNP:575231122
346 346 c, t dbSNP:567724105
352 352 a, g dbSNP:752698122
353 353 a, g dbSNP:779255434
354 354 a, c, g dbSNP:41311975
362 362 a, g dbSNP:771378058
363 363 a, c dbSNP:775164410
367 367 a, t dbSNP:764848572
372 372 c, g, t dbSNP:773447414
373 373 a, g dbSNP:772641061
374 374 c, g dbSNP:748548999
384 384 -, agccc dbSNP:760074158
388 388 -, agccc dbSNP:777169435
388 388 c, t dbSNP:375405887
389 389 a, g dbSNP:372032713
391 391 c, g dbSNP:79133006
392 392 c, t dbSNP:749343738
394 394 a, g, t dbSNP:756389201
408 408 g, t dbSNP:745739794
413 413 g, t dbSNP:536418941
414 414 a, t dbSNP:375205262
418 418 a, t dbSNP:115934645
426 426 a, g dbSNP:763987657
429 429 c, g dbSNP:757953891
431 431 c, t dbSNP:752191942
432 432 a, c, t dbSNP:764938362
433 433 g, t dbSNP:550808731
437 437 c, t dbSNP:759124753
438 438 a, g dbSNP:773642386
447 447 c, t dbSNP:374450055
448 448 c, t dbSNP:762417766
453 453 a, t dbSNP:371526523
459 459 c, t dbSNP:774756684
460 460 c, t dbSNP:769260812
466 466 c, g dbSNP:749433788
475 475 a, g dbSNP:201166741
478 478 c, t dbSNP:571307915
483 483 c, t dbSNP:746018547
484 484 a, g dbSNP:781062868
489 489 a, c dbSNP:756962244
490 490 c, g dbSNP:746798268
497 497 c, t dbSNP:777746272
499 499 c, t dbSNP:758328364
500 500 a, g, t dbSNP:778339783
503 503 a, t dbSNP:754684731
505 505 a, g dbSNP:753396840
508 508 a, g dbSNP:766027583
511 511 c, t dbSNP:762130319
512 512 -, c dbSNP:771165550
512 512 a, c, t dbSNP:892090
514 514 c, g dbSNP:763485474
515 515 g, t dbSNP:775726835
516 516 a, c dbSNP:769947136
519 519 c, g dbSNP:759834481
523 523 c, t dbSNP:892089
525 525 c, t dbSNP:771170249
529 529 c, t dbSNP:746844654
533 533 a, g dbSNP:777476310
535 535 a, g dbSNP:5030705
541 541 c, t dbSNP:748027211
542 542 a, g dbSNP:778421895
544 544 c, t dbSNP:754483221
552 552 a, g, t dbSNP:387906919
553 553 c, t dbSNP:367907292
554 554 a, g dbSNP:755790003
564 564 a, g dbSNP:751979972
567 567 c, g dbSNP:764497463
581 581 a, g dbSNP:369568059
583 583 c, g dbSNP:546902436
591 591 c, g dbSNP:753216495
593 593 c, t dbSNP:765744190
595 595 a, c dbSNP:201652983
596 596 c, g dbSNP:41300084
600 600 a, g dbSNP:776766695
601 601 c, g dbSNP:41301959
603 603 c, g, t dbSNP:534339924
604 604 a, c, g dbSNP:1654425
606 606 c, t dbSNP:370855777
612 612 a, g dbSNP:200525940
613 613 c, g dbSNP:768628583
614 614 a, g, t dbSNP:779552982
617 617 a, c dbSNP:755737487
618 618 a, c, g dbSNP:778314910
628 628 g, t dbSNP:758874083
629 629 a, g dbSNP:753098085
658 658 c, t dbSNP:781041470
659 659 c, g, t dbSNP:368555743
660 660 a, g, t dbSNP:373154193
671 671 a, g, t dbSNP:555734027
674 674 -, cc dbSNP:771675174
674 674 c, g dbSNP:766761398
682 682 c, t dbSNP:539172883
683 683 c, t dbSNP:1613662
684 684 a, c dbSNP:767798856
685 685 g, t dbSNP:557946250
710 710 c, g dbSNP:781194651
715 715 a, g dbSNP:199576708
718 718 a, g dbSNP:751766995
721 721 c, t dbSNP:764192104
728 728 a, t dbSNP:762855744
730 730 c, t dbSNP:752421887
736 736 -, cgaa dbSNP:754929349
737 737 a, c, g dbSNP:1654416
737 737 -, g dbSNP:747661380
739 739 -, a dbSNP:778336022
745 745 a, c dbSNP:776301634
747 747 c, g dbSNP:201917182
750 750 c, t dbSNP:760070554
760 760 c, t dbSNP:760286317
773 773 a, g dbSNP:2304167
776 776 a, c dbSNP:202044825
777 777 c, g dbSNP:761318901
790 790 -, a dbSNP:764228426
790 790 a, g dbSNP:775857911
791 791 c, g dbSNP:770106401
796 796 -, tc dbSNP:763180314
797 797 c, g dbSNP:746202039
799 799 a, g dbSNP:373073778
806 806 c, g dbSNP:533241802
809 809 g, t dbSNP:563944012
812 812 c, t dbSNP:540599440
813 813 a, g dbSNP:771474578
827 827 a, t dbSNP:749210453
830 830 a, g dbSNP:747424824
843 843 a, g dbSNP:372829679
844 844 c, g dbSNP:772083213
850 850 c, g, t dbSNP:779332945
853 853 c, t dbSNP:190904614
854 854 a, c, g dbSNP:779660245
856 856 a, g dbSNP:60843302
857 857 a, g dbSNP:750290180
863 863 a, g dbSNP:767460935
871 871 a, t dbSNP:201436629
874 874 a, c dbSNP:751058450
875 875 c, t dbSNP:763803376
879 879 c, t dbSNP:762526564
880 880 a, g dbSNP:754222737
889 889 a, g dbSNP:766612048
898 898 c, t dbSNP:761067320
899 899 a, t dbSNP:773639794
903 903 a, g dbSNP:772616628
904 904 c, g dbSNP:762049176
908 908 c, t dbSNP:201753264
909 909 a, g dbSNP:201997410
915 915 a, c dbSNP:749476604
918 918 a, g dbSNP:779935541
920 920 -, c dbSNP:752850718
923 923 c, t dbSNP:371817808
924 924 a, c, g dbSNP:781050416
926 926 c, t dbSNP:757183693
929 929 a, g dbSNP:751074784
946 946 a, g dbSNP:777208826
949 949 a, g dbSNP:537357993
951 951 c, t dbSNP:752332158
952 952 a, g dbSNP:373346261
953 953 c, t dbSNP:534709050
955 955 c, t dbSNP:750792954
957 957 c, t dbSNP:200151153
958 958 a, g dbSNP:762347897
964 964 c, g dbSNP:2304166
965 965 a, c dbSNP:768821288
966 966 c, t dbSNP:200431311
969 969 -, ccctcccgc dbSNP:760157972
969 969 a, c dbSNP:775626235
970 970 -, cctcccgct dbSNP:771380662
970 970 c, t dbSNP:770045316
973 973 c, t dbSNP:745718736
975 975 c, t dbSNP:780973296
976 976 a, g dbSNP:770868762
978 978 -, cccgca dbSNP:760940207
978 978 a, t dbSNP:1654413
983 983 c, t dbSNP:746907519
984 984 a, g dbSNP:777656189
991 991 a, t dbSNP:757950138
992 992 a, c dbSNP:1671152
994 994 a, c, t dbSNP:754590544
995 995 a, g dbSNP:80348265
997 997 c, g dbSNP:200948100
1003 1003 a, g dbSNP:757874715
1005 1005 a, g dbSNP:752155931
1013 1013 c, t dbSNP:368858591
1014 1014 a, g dbSNP:374509474
1016 1016 c, g dbSNP:775635724
1018 1018 a, g dbSNP:549916040
1019 1019 a, g dbSNP:267605686
1021 1021 g, t dbSNP:759748523
1022 1022 g, t dbSNP:776313503
1025 1025 c, t dbSNP:770751968
1027 1027 c, g dbSNP:746782553
1031 1031 c, t dbSNP:201413568
1032 1032 a, g dbSNP:767901432
1033 1033 c, t dbSNP:747612828
1035 1035 a, g dbSNP:778426724
1044 1044 c, g dbSNP:754606143
1047 1047 a, g dbSNP:201603906
1050 1050 c, t dbSNP:540637093
1051 1051 a, g, t dbSNP:759751882
1057 1057 c, g dbSNP:764765255
1059 1059 c, t dbSNP:527330221
1063 1063 a, g dbSNP:561323272
1066 1066 c, t dbSNP:765312634
1067 1067 a, g dbSNP:186103270
1069 1069 c, t dbSNP:776886080
1070 1070 c, t dbSNP:200019444
1071 1071 a, g dbSNP:557292489
1074 1074 g, t dbSNP:772920810
1078 1078 a, c dbSNP:772006921
1080 1080 g, t dbSNP:375643910
1081 1081 g, t dbSNP:748067631
1089 1089 a, t dbSNP:773762259
1098 1098 g, t dbSNP:768256234
1103 1103 a, g, t dbSNP:779914827
1107 1107 a, c dbSNP:755827734
1112 1112 a, g dbSNP:747382737
1115 1115 g, t dbSNP:778225188
1117 1117 c, t dbSNP:373596955
1118 1118 a, c, g dbSNP:370477228
1120 1120 -, g dbSNP:773558453
1123 1123 c, t dbSNP:755141586
1126 1126 a, t dbSNP:753910818
1129 1129 a, g, t dbSNP:377522937
1137 1137 a, t dbSNP:750237644
1144 1144 c, t dbSNP:767299494
1147 1147 a, c dbSNP:761484721
1149 1149 g, t dbSNP:774398889
1153 1153 c, t dbSNP:751635237
1154 1154 a, c, g dbSNP:775074233
1155 1155 a, g dbSNP:769584360
1165 1165 c, t dbSNP:745470892
1166 1166 a, c, g dbSNP:182940784
1173 1173 c, t dbSNP:748445118
1175 1175 c, g dbSNP:779540658
1182 1182 c, t dbSNP:755373331
1184 1184 -, cct dbSNP:771635825
1184 1184 c, g, t dbSNP:199813278
1185 1185 c, t dbSNP:780055487
1190 1190 a, g dbSNP:756358091
1192 1192 g, t dbSNP:750681822
1206 1206 a, g dbSNP:767614700
1209 1209 c, t dbSNP:761729129
1210 1210 g, t dbSNP:751311313
1215 1215 -, tgtc dbSNP:59110861
1215 1215 c, g dbSNP:200940260
1218 1218 -, ttgt dbSNP:747748721
1220 1220 c, t dbSNP:762927953
1222 1222 a, c, t dbSNP:769390004
1223 1223 a, c dbSNP:759087504
1226 1226 -, tctgtctg dbSNP:768134535
1228 1228 c, t dbSNP:776401390
1229 1229 -, tctg dbSNP:773724485
1230 1230 -, tctg dbSNP:775950031
1230 1230 c, t dbSNP:766715406
1233 1233 -, tctg, tctgtctg dbSNP:138680589
1237 1237 c, t dbSNP:748550203
1238 1238 c, t dbSNP:779088536
1249 1249 a, g dbSNP:769169673
1256 1256 c, t dbSNP:749752950
1264 1264 a, g dbSNP:370026589
1266 1266 c, t dbSNP:780505285
1268 1268 c, g dbSNP:150807394
1273 1273 a, c dbSNP:566107894
1276 1276 c, g dbSNP:745937021
1289 1289 a, g dbSNP:781548792
1299 1299 c, g dbSNP:555783596
1311 1311 a, g dbSNP:74697203
1313 1313 a, t dbSNP:763747397
1318 1318 c, t dbSNP:758443526
1328 1328 c, g dbSNP:752723824
1337 1337 c, g dbSNP:570109671
1346 1346 c, t dbSNP:759181602
1353 1353 c, t dbSNP:775936716
1357 1357 a, g dbSNP:766068188
1361 1361 c, g dbSNP:760193172
1365 1365 a, c dbSNP:774805420
1373 1373 c, g, t dbSNP:201940503
1380 1380 c, t dbSNP:776037769
1381 1381 a, g dbSNP:770284082
1396 1396 c, t dbSNP:745968195
1404 1404 c, t dbSNP:533111925
1416 1416 c, t dbSNP:369436148
1440 1440 c, t dbSNP:747159406
1443 1443 c, t dbSNP:1671151
1449 1449 -, t dbSNP:780995686
1452 1452 c, t dbSNP:377575412
1458 1458 c, t dbSNP:776592723
1459 1459 a, c dbSNP:765268240
1460 1460 c, t dbSNP:754904771
1464 1464 a, g dbSNP:753409870
1470 1470 -, tt dbSNP:758728587
1470 1470 c, t dbSNP:765762954
1482 1482 c, t dbSNP:760198171
1483 1483 c, t dbSNP:141737256
1484 1484 c, t dbSNP:768546634
1491 1491 c, t dbSNP:199561271
1507 1507 a, g dbSNP:763379117
1511 1511 c, t dbSNP:775768250
1513 1513 c, t dbSNP:368961812
1518 1518 c, t dbSNP:770304194
1519 1519 a, g dbSNP:41275822
1520 1520 a, g dbSNP:776805197
1533 1533 -, cct dbSNP:765453546
1533 1533 -, tc dbSNP:752938783
1533 1533 c, t dbSNP:770957240
1539 1539 a, c, g dbSNP:146318651
1547 1547 c, g dbSNP:772352178
1549 1549 a, g dbSNP:142053457
1550 1550 c, t dbSNP:778801507
1551 1551 a, c, g dbSNP:753756120
1553 1553 a, g dbSNP:780015649
1554 1554 a, t dbSNP:755635088
1555 1555 c, g dbSNP:200399196
1569 1569 a, g dbSNP:374982514
1574 1574 c, g, t dbSNP:200566792
1576 1576 c, t dbSNP:753087191
1579 1579 c, t dbSNP:375130495
1580 1580 g, t dbSNP:372569183
1589 1589 c, t dbSNP:368350811
1591 1591 a, c dbSNP:777054385
1592 1592 a, g dbSNP:768061284
1602 1602 a, t dbSNP:771458181
1606 1606 c, t dbSNP:760673543
1610 1610 g, t dbSNP:374590810
1613 1613 c, t dbSNP:772444957
1614 1614 a, g dbSNP:748340999
1619 1619 c, t dbSNP:771846036
1623 1623 c, g dbSNP:372175929
1629 1629 a, g dbSNP:768381545
1638 1638 g, t dbSNP:749092940
1639 1639 a, g dbSNP:779925828
1645 1645 c, t dbSNP:578145430
1647 1647 a, g dbSNP:368531531
1649 1649 g, t dbSNP:780636331
1652 1652 a, g dbSNP:756934246
1654 1654 a, g dbSNP:751253075
1668 1668 c, t dbSNP:763715619
1670 1670 a, t dbSNP:759878316
1671 1671 c, t dbSNP:754162124
1673 1673 a, g dbSNP:766808148
1681 1681 a, g dbSNP:201681535
1683 1683 a, c, g dbSNP:772313424
1686 1686 -, aaaaa dbSNP:759672977
1690 1690 -, a dbSNP:754459187
1706 1706 c, g dbSNP:761959070
1711 1711 g, t dbSNP:774769403
1716 1716 g, t dbSNP:768916446
1728 1728 c, g dbSNP:749043915
1738 1738 c, t dbSNP:775300532
1740 1740 c, t dbSNP:541786453
1741 1741 a, g dbSNP:1654412
1745 1745 g, t dbSNP:781077689
1746 1746 -, g dbSNP:766797825
1748 1748 a, t dbSNP:756811244
1749 1749 a, g, t dbSNP:777356988
1750 1750 a, g dbSNP:758008926
1751 1751 a, g dbSNP:10418074
1756 1756 g, t dbSNP:766725027
1761 1761 g, t dbSNP:756516167
1766 1766 c, t dbSNP:751011830
1769 1769 g, t dbSNP:372168591
1776 1776 -, tccc dbSNP:761185718
1789 1789 a, g dbSNP:190384471
1806 1806 c, t dbSNP:774503825
1813 1813 a, c dbSNP:115459014
1829 1829 c, t dbSNP:2886416
1830 1830 a, g dbSNP:775183932
1840 1840 c, t dbSNP:1671150
1843 1843 a, g dbSNP:745640729
1844 1844 c, t dbSNP:570669348
1845 1845 a, c dbSNP:770852322
1849 1849 a, g dbSNP:746533320
1850 1850 a, c dbSNP:777286436
1860 1860 g, t dbSNP:758016611
1896 1896 c, t dbSNP:747874978
1897 1897 a, g dbSNP:778403744
1898 1898 c, g, t dbSNP:138796044
1906 1906 -, atgtac dbSNP:761491834
1911 1911 a, c dbSNP:76129219
1919 1919 c, t dbSNP:567986876
1921 1921 a, g dbSNP:547798735
1936 1936 a, t dbSNP:186874802
1948 1948 g, t dbSNP:562322946
1949 1949 a, c dbSNP:10417981
1973 1973 -, aaataa dbSNP:770364130
1982 1982 a, g dbSNP:532098985
1989 1989 c, t dbSNP:752994413
2000 2000 c, t dbSNP:10417943
2027 2027 a, g dbSNP:541590036
2045 2045 a, g dbSNP:572797096
2060 2060 a, t dbSNP:562331603
2067 2067 a, g dbSNP:542141082
2074 2074 c, t dbSNP:769718229
2118 2118 a, g dbSNP:564914757
2129 2129 a, c dbSNP:143249922
2135 2135 c, t dbSNP:149570465
2159 2159 a, g dbSNP:780731263
2193 2193 c, g dbSNP:750698868
2213 2213 c, t dbSNP:565777020
2222 2222 c, t dbSNP:41275820
2244 2244 a, g dbSNP:533705783

Target ORF information:

RefSeq Version NM_016363
Organism Homo sapiens (human)
Definition Homo sapiens glycoprotein VI (platelet) (GP6), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_016363

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCTCCAT CCCCGACCGC CCTCTTCTGT CTTGGGCTGT GTCTGGGGCG TGTGCCAGCG 
CAGAGTGGAC CGCTCCCCAA GCCCTCCCTC CAGGCTCTGC CCAGCTCCCT GGTGCCCCTG
GAGAAGCCAG TGACCCTCCG GTGCCAGGGA CCTCCGGGCG TGGACCTGTA CCGCCTGGAG
AAGCTGAGTT CCAGCAGGTA CCAGGATCAG GCAGTCCTCT TCATCCCGGC CATGAAGAGA
AGTCTGGCTG GACGCTACCG CTGCTCCTAC CAGAACGGAA GCCTCTGGTC CCTGCCCAGC
GACCAGCTGG AGCTCGTTGC CACGGGAGTT TTTGCCAAAC CCTCGCTCTC AGCCCAGCCC
GGCCCGGCGG TGTCGTCAGG AGGGGACGTA ACCCTACAGT GTCAGACTCG GTATGGCTTT
GACCAATTTG CTCTGTACAA GGAAGGGGAC CCTGCGCCCT ACAAGAATCC CGAGAGATGG
TACAGGGCTA GTTTTCCCAT CATCACGGTG ACCGCCGCCC ACAGCGGAAC CTACCGATGC
TACAGCTTCT CCAGCAGGGA CCCATACCTG TGGTCAGCCC CCAGCGACCC CCTGGAGCTT
GTGGTCACAG GAACCTCTGT GACCCCCAGC CGGTTACCAA CAGAACCACC TTCCCCGGTA
GCAGAATTCT CAGAAGCCAC CGCTGAACTG ACCGTCTCAT TCACAAACGA AGTCTTCACA
ACTGAGACTT CTAGGAGTAT CACCGCCAGT CCAAAGGAGT CAGACTCTCC AGCTGGTCCT
GCCCGCCAGT ACTACACCAA GGGCAACCTG GTCCGGATAT GCCTCGGGGC TGTGATCCTA
ATAATCCTGG CGGGGTTTCT GGCAGAGGAC TGGCACAGCC GGAGGAAGCG CCTGCGGCAC
AGGGGCAGGG CTGTGCAGAG GCCGCTTCCG CCCCTCCCGC CCCTCCCGCT GACCCGGAAA
TCAAACGGGG GTCAGGATGG AGGCCGACAG GATGTTCACA GCCGCGGGTT ATGTTCATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.