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PDCD2 programmed cell death 2 [Homo sapiens (human)]

Gene Symbol PDCD2
Entrez Gene ID 5134
Full Name programmed cell death 2
Synonyms RP8, ZMYND7
General protein information
Preferred Names
programmed cell death protein 2
Names
programmed cell death protein 2
zinc finger protein Rp-8
zinc finger MYND domain-containing protein 7
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6q27

Summary This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010]. lac of sum
Disorder MIM:

600866

Disorder Html:
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OHu59550 XM_011535878 PREDICTED: Homo sapiens programmed cell death 2 (PDCD2), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK Not in stock -1 Starting from $99.00
OHu59551 XM_011535879 PREDICTED: Homo sapiens programmed cell death 2 (PDCD2), transcript variant X3, mRNA. pcDNA3.1-C-(k)DYK Not in stock -1 Starting from $99.00
OHu12183 NM_002598 Homo sapiens programmed cell death 2 (PDCD2), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK In stock -1 Starting from $99.00
OHu09878 NM_144781 Homo sapiens programmed cell death 2 (PDCD2), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK Not in stock -1 Starting from $99.00
OHu09885 NM_001199461 Homo sapiens programmed cell death 2 (PDCD2), transcript variant 3, mRNA. pcDNA3.1-C-(k)DYK Not in stock -1 Starting from $99.00
OHu12040 NM_001199463 Homo sapiens programmed cell death 2 (PDCD2), transcript variant 5, mRNA. pcDNA3.1-C-(k)DYK Not in stock 7-9 Starting from $99.00
OHu10456 NM_001199464 Homo sapiens programmed cell death 2 (PDCD2), transcript variant 6, mRNA. pcDNA3.1-C-(k)DYK Not in stock 7-9 Starting from $99.00
OHu09435 NM_001199462 Homo sapiens programmed cell death 2 (PDCD2), transcript variant 4, mRNA. pcDNA3.1-C-(k)DYK Not in stock 7-9 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OHu59550D
Sequence Information ORF Nucleotide Sequence (Length: 951bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product programmed cell death protein 2 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_025741.16) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCGAGAG GTTTCCTCTG CCCCGTTCCC TCGCATTGGT CCTGCAACCG CTCCCGTCAG 
ACGCGTTTCC GCCTCCTGTC CTCCGGAAAG GTGCCCGCCT CTTGCCTTCC GGCCCGGCGC
CCGATTTCCG CCTTCCGACC CAGCTGTGGG CTGCGCCCCA CGCCAGCCCG CGCCCCGCAT
GGCTGCCGCC GGGGCCAGGC CTGTGGAGCT GGGCTTCGCC GAGTCGGCGC CGGCGTGGCG
ACTGCGCAGC GAGCAGTTCC CCAGCAAGGT GGGCGGGCGG CCGGCATGGC TGGGCGCGGC
CGGGCTGCCG GGGCCCCAGG CCCTGGCCTG CGAGCTGTGC GGCCGCCCGC TCTCCTTCCT
GCTGCAGGTG TATGCGCCGC TGCCTGGCCG CCCGGACGCC TTCCACCGCT GCATCTTCCT
CTTCTGCTGC CGCGAGCAGC CGTGCTGTGC CGGCCTGCGA GGGTTTGTGG CTGTTTAGGC
CCCAAAACGT GCTCCAGATG CCACAAAGCA TATTACTGCA GCAAGGAGCA TCAGACCCTA
GACTGGAGAT TGGGACATAA GCAGGCTTGT GCACAACCAG ATCATCTGGA CCATATAATT
CCAGACCACA ACTTCCTTTT TCCAGAATTT GAAATTGTAA TAGAAACAGA AGATGAGATT
ATGCCTGAGG TTGTGGAAAA GGAAGATTAC TCAGAGATTA TAGGGAGCAT GGGTGAAGCA
CTTGAGGAAG AACTGGATTC CATGGCAAAA CATGAATCCA GGGAAGATAA AATTTTTCAG
AAGTTTAAAA CTCAGATAGC CCTTGAACCA GAACAGATTC TTAGATATGG CAGAGGTATT
GCCCCCATCT GGATTTCTGG TGAAAATATT CCTCAAGAAA AGGATATTCC AGATTGCCCC
TGTGGTGCCA AGAGAATATT GGAATTCCAG TTTTCAGACA CGGTCTATTTG A
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqXP_011534180.1
CDS16..966
Misc Feature(1)478..585(+)
Misc Feature(2)616..>945(+)
Translation
Position Chain Variation Link
32 32 c, t dbSNP:577789627
78 78 a, g dbSNP:556003966
86 86 c, g dbSNP:113211980
102 102 a, g dbSNP:775062666
112 112 a, g dbSNP:186446776
128 128 c, t dbSNP:181785308
131 131 a, g dbSNP:564796099
143 143 c, t dbSNP:555386885
146 146 c, t dbSNP:534289056
156 156 c, g dbSNP:566808900
166 166 a, c dbSNP:78712376
173 173 c, g, t dbSNP:760052977
174 174 c, t dbSNP:771116468
178 178 c, t dbSNP:539613984
181 181 a, g dbSNP:532832776
183 183 c, t dbSNP:773206106
202 202 c, t dbSNP:551275548
208 208 g, t dbSNP:529662275
209 209 a, g dbSNP:567261750
230 230 a, t dbSNP:548662103
235 235 c, t dbSNP:527284090
239 239 c, t dbSNP:559964311
275 275 c, t dbSNP:773036976
277 277 c, t dbSNP:371862236
280 280 c, g dbSNP:545103128
312 312 c, t dbSNP:769150716
317 317 a, g dbSNP:749670057
319 319 a, g dbSNP:779749524
326 326 c, g dbSNP:755759947
331 331 c, t dbSNP:749923770
345 345 a, c, g dbSNP:757144594
346 346 a, c, g dbSNP:763817884
356 356 a, g dbSNP:762795976
361 361 c, t dbSNP:752501719
363 363 a, c dbSNP:61756020
364 364 a, g dbSNP:376113327
367 367 c, g dbSNP:532945174
373 373 c, t dbSNP:772313263
376 376 g, t dbSNP:189419068
377 377 c, t dbSNP:562369624
393 393 c, t dbSNP:774982075
397 397 g, t dbSNP:769349011
399 399 c, g dbSNP:74482927
400 400 g, t dbSNP:780328713
401 401 a, g dbSNP:769437764
405 405 g, t dbSNP:745536645
409 409 a, g dbSNP:200023629
413 413 g, t dbSNP:756772582
425 425 a, t dbSNP:751128316
426 426 a, g dbSNP:777682956
428 428 a, g dbSNP:555642254
436 436 c, t dbSNP:200905773
439 439 c, t dbSNP:764967878
448 448 c, t dbSNP:760914642
452 452 c, g dbSNP:750683402
454 454 g, t dbSNP:11557807
455 455 c, t dbSNP:200184000
456 456 c, t dbSNP:117413937
457 457 a, g dbSNP:774609988
467 467 a, g dbSNP:764637050
470 470 c, t dbSNP:1129634
474 474 a, g dbSNP:763390393
480 480 g, t dbSNP:777853006
486 486 c, g dbSNP:758688151
488 488 -, g dbSNP:145487503
489 489 g, t dbSNP:752697924
491 491 g, t dbSNP:779072921
492 492 a, g, t dbSNP:754349565
493 493 a, g dbSNP:766675033
495 495 c, t dbSNP:139143204
497 497 c, g, t dbSNP:767050564
499 499 a, c dbSNP:761545534
506 506 g, t dbSNP:372293466
507 507 c, t dbSNP:768284300
508 508 c, t dbSNP:762924182
509 509 c, g dbSNP:149555889
516 516 c, t dbSNP:561949385
523 523 a, c, g dbSNP:368569104
525 525 a, g dbSNP:772138191
527 527 a, g dbSNP:748435640
549 549 c, g dbSNP:778899901
551 551 a, c dbSNP:375620318
553 553 c, t dbSNP:755066452
560 560 a, g dbSNP:753980808
563 563 c, g dbSNP:780538358
572 572 a, g dbSNP:756658704
573 573 c, t dbSNP:201859590
574 574 a, g dbSNP:750701272
576 576 a, g dbSNP:767952037
580 580 c, g dbSNP:756790601
587 587 c, t dbSNP:772263336
594 594 a, c, g, t dbSNP:183277217
601 601 c, t dbSNP:764842993
609 609 c, t dbSNP:759350919
625 625 a, g dbSNP:776651392
626 626 a, g dbSNP:766274052
629 629 c, t dbSNP:778255010
630 630 c, t dbSNP:760484527
631 631 a, c dbSNP:773053732
634 634 c, t dbSNP:375838507
636 636 c, t dbSNP:749520124
637 637 c, t dbSNP:577424007
639 639 a, g dbSNP:769941780
651 651 g, t dbSNP:558824933
652 652 a, g dbSNP:373202680
661 661 a, g dbSNP:781338071
663 663 a, g dbSNP:770898248
666 666 -, aga dbSNP:561114246
667 667 a, g dbSNP:757772974
672 672 c, g, t dbSNP:778296317
677 677 -, t dbSNP:769614520
679 679 c, t dbSNP:758056878
686 686 c, t dbSNP:752427699
687 687 g, t dbSNP:778236042
688 688 a, g dbSNP:754486906
695 695 -, a dbSNP:745678386
709 709 a, g dbSNP:753325570
720 720 a, g dbSNP:766332437
721 721 a, g dbSNP:760583517
723 723 a, c dbSNP:192662962
724 724 a, g dbSNP:767335031
737 737 c, t dbSNP:779199451
738 738 a, t dbSNP:369266049
741 741 -, gga dbSNP:752874669
746 746 a, g dbSNP:138337157
748 748 c, g dbSNP:150472476
756 756 c, t dbSNP:758887507
757 757 a, g dbSNP:376751655
758 758 c, t dbSNP:745426165
764 764 a, c dbSNP:141160861
770 770 a, c dbSNP:757244867
773 773 a, c, t dbSNP:56926064
793 793 c, t dbSNP:763802273
794 794 a, g dbSNP:202247759
798 798 g, t dbSNP:755188301
808 808 a, c dbSNP:754029431
810 810 c, g dbSNP:766755961
811 811 -, atag dbSNP:773552634
823 823 c, t dbSNP:760804113
850 850 a, g dbSNP:774703417
857 857 c, t dbSNP:764705175
858 858 c, t dbSNP:199584824
862 862 a, c dbSNP:763226032
865 865 c, t dbSNP:775892587
867 867 c, g dbSNP:769380262
873 873 c, t dbSNP:759193086
877 877 a, g dbSNP:776080602
881 881 a, g dbSNP:140553523
893 893 a, g dbSNP:140573137
899 899 a, g dbSNP:777538268
907 907 c, g dbSNP:772112538
908 908 a, g dbSNP:747878373
918 918 c, t dbSNP:778862443
934 934 c, t dbSNP:756334058
971 971 c, g dbSNP:182216998
981 981 a, g dbSNP:149764685
982 982 a, g dbSNP:768553602
988 988 a, c dbSNP:529226086
989 989 c, t dbSNP:748625597
997 997 a, c, g dbSNP:3173219
1000 1000 c, t dbSNP:78106167
1002 1002 c, g dbSNP:751537748
1040 1040 c, t dbSNP:528514820
1051 1051 g, t dbSNP:564558091
1078 1078 a, c dbSNP:755327497
1095 1095 a, g dbSNP:562342254
1116 1116 c, t dbSNP:557862399

Target ORF information:

RefSeq Version XM_011535878
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens programmed cell death 2 (PDCD2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
XM_011535878

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCCGAGAG GTTTCCTCTG CCCCGTTCCC TCGCATTGGT CCTGCAACCG CTCCCGTCAG 
ACGCGTTTCC GCCTCCTGTC CTCCGGAAAG GTGCCCGCCT CTTGCCTTCC GGCCCGGCGC
CCGATTTCCG CCTTCCGACC CAGCTGTGGG CTGCGCCCCA CGCCAGCCCG CGCCCCGCAT
GGCTGCCGCC GGGGCCAGGC CTGTGGAGCT GGGCTTCGCC GAGTCGGCGC CGGCGTGGCG
ACTGCGCAGC GAGCAGTTCC CCAGCAAGGT GGGCGGGCGG CCGGCATGGC TGGGCGCGGC
CGGGCTGCCG GGGCCCCAGG CCCTGGCCTG CGAGCTGTGC GGCCGCCCGC TCTCCTTCCT
GCTGCAGGTG TATGCGCCGC TGCCTGGCCG CCCGGACGCC TTCCACCGCT GCATCTTCCT
CTTCTGCTGC CGCGAGCAGC CGTGCTGTGC CGGCCTGCGA GGGTTTGTGG CTGTTTAGGC
CCCAAAACGT GCTCCAGATG CCACAAAGCA TATTACTGCA GCAAGGAGCA TCAGACCCTA
GACTGGAGAT TGGGACATAA GCAGGCTTGT GCACAACCAG ATCATCTGGA CCATATAATT
CCAGACCACA ACTTCCTTTT TCCAGAATTT GAAATTGTAA TAGAAACAGA AGATGAGATT
ATGCCTGAGG TTGTGGAAAA GGAAGATTAC TCAGAGATTA TAGGGAGCAT GGGTGAAGCA
CTTGAGGAAG AACTGGATTC CATGGCAAAA CATGAATCCA GGGAAGATAA AATTTTTCAG
AAGTTTAAAA CTCAGATAGC CCTTGAACCA GAACAGATTC TTAGATATGG CAGAGGTATT
GCCCCCATCT GGATTTCTGG TGAAAATATT CCTCAAGAAA AGGATATTCC AGATTGCCCC
TGTGGTGCCA AGAGAATATT GGAATTCCAG TTTTCAGACA CGGTCTATTTG A

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu59551D
Sequence Information ORF Nucleotide Sequence (Length: 720bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product programmed cell death protein 2 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_025741.16) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
ATGCCGAGAG GTTTCCTCTG CCCCGTTCCC TCGCATTGGT CCTGCAACCG CTCCCGTCAG 
ACGCGTTTCC GCCTCCTGTC CTCCGGAAAG GTGCCCGCCT CTTGCCTTCC GGCCCGGCGC
CCGATTTCCG CCTTCCGACC CAGCTGTGGG CTGCGCCCCA CGCCAGCCCG CGCCCCGCAT
GGCTGCCGCC GGGGCCAGGC CTGTGGAGCT GGGCTTCGCC GAGTCGGCGC CGGCGTGGCG
ACTGCGCAGC GAGCAGTTCC CCAGCAAGGT GGGCGGGCGG CCGGCATGGC TGGGCGCGGC
CGGGCTGCCG GGGCCCCAGG CCCTGGCCTG CGAGCTGTGC GGCCGCCCGC TCTCCTTCCT
GCTGCAGGTG TATGCGCCGC TGCCTGGCCG CCCGGACGCC TTCCACCGCT GCATCTTCCT
CTTCTGCTGC CGCGAGCAGC CGTGCTGTGC CGGCCTGCGA GGGTTTGTGG CTGTTTAGGC
CCCAAAACGT GCTCCAGATG CCACAAAGCA TATTACTGCA GCAAGGAGCA TCAGACCCTA
GACTGGAGAT TGGGACATAA GCAGGCTTGT GCACAACCAG ATCATCTGGA CCATATAATT
CCAGACCACA ACTTCCTTTT TCCAGAATTT GAAATTGTAA TAGAAACAGA AGATGAGATT
ATGCCTGAGG TTGTGGAAAA GGAAGATTAC TCAGAGATTA TAGGGAGCAT GGGGATATAA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqXP_011534181.1
CDS16..735
Misc Feature(1)478..585(+)
Translation
Position Chain Variation Link
32 32 c, t dbSNP:577789627
78 78 a, g dbSNP:556003966
86 86 c, g dbSNP:113211980
102 102 a, g dbSNP:775062666
112 112 a, g dbSNP:186446776
128 128 c, t dbSNP:181785308
131 131 a, g dbSNP:564796099
143 143 c, t dbSNP:555386885
146 146 c, t dbSNP:534289056
156 156 c, g dbSNP:566808900
166 166 a, c dbSNP:78712376
173 173 c, g, t dbSNP:760052977
174 174 c, t dbSNP:771116468
178 178 c, t dbSNP:539613984
181 181 a, g dbSNP:532832776
183 183 c, t dbSNP:773206106
202 202 c, t dbSNP:551275548
208 208 g, t dbSNP:529662275
209 209 a, g dbSNP:567261750
230 230 a, t dbSNP:548662103
235 235 c, t dbSNP:527284090
239 239 c, t dbSNP:559964311
275 275 c, t dbSNP:773036976
277 277 c, t dbSNP:371862236
280 280 c, g dbSNP:545103128
312 312 c, t dbSNP:769150716
317 317 a, g dbSNP:749670057
319 319 a, g dbSNP:779749524
326 326 c, g dbSNP:755759947
331 331 c, t dbSNP:749923770
345 345 a, c, g dbSNP:757144594
346 346 a, c, g dbSNP:763817884
356 356 a, g dbSNP:762795976
361 361 c, t dbSNP:752501719
363 363 a, c dbSNP:61756020
364 364 a, g dbSNP:376113327
367 367 c, g dbSNP:532945174
373 373 c, t dbSNP:772313263
376 376 g, t dbSNP:189419068
377 377 c, t dbSNP:562369624
393 393 c, t dbSNP:774982075
397 397 g, t dbSNP:769349011
399 399 c, g dbSNP:74482927
400 400 g, t dbSNP:780328713
401 401 a, g dbSNP:769437764
405 405 g, t dbSNP:745536645
409 409 a, g dbSNP:200023629
413 413 g, t dbSNP:756772582
425 425 a, t dbSNP:751128316
426 426 a, g dbSNP:777682956
428 428 a, g dbSNP:555642254
436 436 c, t dbSNP:200905773
439 439 c, t dbSNP:764967878
448 448 c, t dbSNP:760914642
452 452 c, g dbSNP:750683402
454 454 g, t dbSNP:11557807
455 455 c, t dbSNP:200184000
456 456 c, t dbSNP:117413937
457 457 a, g dbSNP:774609988
467 467 a, g dbSNP:764637050
470 470 c, t dbSNP:1129634
474 474 a, g dbSNP:763390393
480 480 g, t dbSNP:777853006
486 486 c, g dbSNP:758688151
488 488 -, g dbSNP:145487503
489 489 g, t dbSNP:752697924
491 491 g, t dbSNP:779072921
492 492 a, g, t dbSNP:754349565
493 493 a, g dbSNP:766675033
495 495 c, t dbSNP:139143204
497 497 c, g, t dbSNP:767050564
499 499 a, c dbSNP:761545534
506 506 g, t dbSNP:372293466
507 507 c, t dbSNP:768284300
508 508 c, t dbSNP:762924182
509 509 c, g dbSNP:149555889
516 516 c, t dbSNP:561949385
523 523 a, c, g dbSNP:368569104
525 525 a, g dbSNP:772138191
527 527 a, g dbSNP:748435640
549 549 c, g dbSNP:778899901
551 551 a, c dbSNP:375620318
553 553 c, t dbSNP:755066452
560 560 a, g dbSNP:753980808
563 563 c, g dbSNP:780538358
572 572 a, g dbSNP:756658704
573 573 c, t dbSNP:201859590
574 574 a, g dbSNP:750701272
576 576 a, g dbSNP:767952037
580 580 c, g dbSNP:756790601
587 587 c, t dbSNP:772263336
594 594 a, c, g, t dbSNP:183277217
601 601 c, t dbSNP:764842993
609 609 c, t dbSNP:759350919
625 625 a, g dbSNP:776651392
626 626 a, g dbSNP:766274052
629 629 c, t dbSNP:778255010
630 630 c, t dbSNP:760484527
631 631 a, c dbSNP:773053732
634 634 c, t dbSNP:375838507
636 636 c, t dbSNP:749520124
637 637 c, t dbSNP:577424007
639 639 a, g dbSNP:769941780
651 651 g, t dbSNP:558824933
652 652 a, g dbSNP:373202680
661 661 a, g dbSNP:781338071
663 663 a, g dbSNP:770898248
666 666 -, aga dbSNP:561114246
667 667 a, g dbSNP:757772974
672 672 c, g, t dbSNP:778296317
677 677 -, t dbSNP:769614520
679 679 c, t dbSNP:758056878
686 686 c, t dbSNP:752427699
687 687 g, t dbSNP:778236042
688 688 a, g dbSNP:754486906
695 695 -, a dbSNP:745678386
709 709 a, g dbSNP:753325570
720 720 a, g dbSNP:766332437
721 721 a, g dbSNP:760583517
723 723 a, c dbSNP:192662962
724 724 a, g dbSNP:767335031
740 740 a, g dbSNP:779439052
752 752 a, g dbSNP:137952379
760 760 c, g dbSNP:750386447
776 776 c, t dbSNP:767494490
793 793 c, t dbSNP:186453867
857 857 c, t dbSNP:143812529
863 863 a, g dbSNP:373484547
880 880 c, g dbSNP:559652433
888 888 c, t dbSNP:778597560
892 892 a, g dbSNP:771234300
898 898 -, gt dbSNP:763430058
911 911 c, t dbSNP:183073999
942 942 c, t dbSNP:748879621
1011 1011 -, t dbSNP:541318061
1016 1016 c, t dbSNP:73258630
1038 1038 a, t dbSNP:12189695
1039 1039 -, gagt dbSNP:776001128
1073 1073 a, c dbSNP:561256815
1085 1085 a, c dbSNP:11557805
1097 1097 -, a dbSNP:146081543
1113 1113 g, t dbSNP:755535521
1141 1141 c, t dbSNP:532721323
1148 1148 a, t dbSNP:190814380
1151 1151 c, t dbSNP:543700179
1161 1161 -, ta dbSNP:773914040
1208 1208 a, g dbSNP:750978426
1220 1220 a, g dbSNP:148995772
1234 1234 a, c dbSNP:554846490
1235 1235 a, g dbSNP:185462539
1239 1239 c, t dbSNP:138944210

Target ORF information:

RefSeq Version XM_011535879
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens programmed cell death 2 (PDCD2), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
XM_011535879

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGCCGAGAG GTTTCCTCTG CCCCGTTCCC TCGCATTGGT CCTGCAACCG CTCCCGTCAG 
ACGCGTTTCC GCCTCCTGTC CTCCGGAAAG GTGCCCGCCT CTTGCCTTCC GGCCCGGCGC
CCGATTTCCG CCTTCCGACC CAGCTGTGGG CTGCGCCCCA CGCCAGCCCG CGCCCCGCAT
GGCTGCCGCC GGGGCCAGGC CTGTGGAGCT GGGCTTCGCC GAGTCGGCGC CGGCGTGGCG
ACTGCGCAGC GAGCAGTTCC CCAGCAAGGT GGGCGGGCGG CCGGCATGGC TGGGCGCGGC
CGGGCTGCCG GGGCCCCAGG CCCTGGCCTG CGAGCTGTGC GGCCGCCCGC TCTCCTTCCT
GCTGCAGGTG TATGCGCCGC TGCCTGGCCG CCCGGACGCC TTCCACCGCT GCATCTTCCT
CTTCTGCTGC CGCGAGCAGC CGTGCTGTGC CGGCCTGCGA GGGTTTGTGG CTGTTTAGGC
CCCAAAACGT GCTCCAGATG CCACAAAGCA TATTACTGCA GCAAGGAGCA TCAGACCCTA
GACTGGAGAT TGGGACATAA GCAGGCTTGT GCACAACCAG ATCATCTGGA CCATATAATT
CCAGACCACA ACTTCCTTTT TCCAGAATTT GAAATTGTAA TAGAAACAGA AGATGAGATT
ATGCCTGAGG TTGTGGAAAA GGAAGATTAC TCAGAGATTA TAGGGAGCAT GGGGATATAA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu12183D
Sequence Information ORF Nucleotide Sequence (Length: 1035bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product programmed cell death protein 2 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL031259.1, BC008378.1 and AK055180.1. On Dec 10, 2010 this sequence version replaced gi:21735591. Summary: This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010]. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: S78085.1, BC008378.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962337 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCTGCCG CCGGGGCCAG GCCTGTGGAG CTGGGCTTCG CCGAGTCGGC GCCGGCGTGG 
CGACTGCGCA GCGAGCAGTT CCCCAGCAAG GTGGGCGGGC GGCCGGCATG GCTGGGCGCG
GCCGGGCTGC CGGGGCCCCA GGCCCTGGCC TGCGAGCTGT GCGGCCGCCC GCTCTCCTTC
CTGCTGCAGG TGTATGCGCC GCTGCCTGGC CGCCCGGACG CCTTCCACCG CTGCATCTTC
CTCTTCTGCT GCCGCGAGCA GCCGTGCTGT GCCGGCCTGC GAGTTTTTAG GAATCAACTA
CCCAGGAAAA ACGATTTTTA CTCATATGAG CCACCTTCTG AGAATCCTCC CCCAGAAACA
GGAGAATCAG TGTGTCTCCA GCTTAAGTCT GGTGCTCATC TCTGCAGGGT TTGTGGCTGT
TTAGGCCCCA AAACGTGCTC CAGATGCCAC AAAGCATATT ACTGCAGCAA GGAGCATCAG
ACCCTAGACT GGAGATTGGG ACATAAGCAG GCTTGTGCAC AACCAGATCA TCTGGACCAT
ATAATTCCAG ACCACAACTT CCTTTTTCCA GAATTTGAAA TTGTAATAGA AACAGAAGAT
GAGATTATGC CTGAGGTTGT GGAAAAGGAA GATTACTCAG AGATTATAGG GAGCATGGGT
GAAGCACTTG AGGAAGAACT GGATTCCATG GCAAAACATG AATCCAGGGA AGATAAAATT
TTTCAGAAGT TTAAAACTCA GATAGCCCTT GAACCAGAAC AGATTCTTAG ATATGGCAGA
GGTATTGCCC CCATCTGGAT TTCTGGTGAA AATATTCCTC AAGAAAAGGA TATTCCAGAT
TGCCCCTGTG GTGCCAAGAG AATATTGGAA TTCCAGGTCA TGCCTCAGCT CCTAAACTAC
CTGAAGGCTG ACAGACTGGG CAAGAGCATT GACTGGGGCA TCCTGGCTGT CTTCACCTGT
GCTGAGAGCT GCAGCTTGGG TACTGGCTAT ACAGAAGAAT TTGTGTGGAA GCAGGATGTA
ACAGATACAC CGTAA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_002589.2
CDS112..1146
Misc Feature(1)514..627(+)
Misc Feature(2)658..1134(+)
Exon (1)1..394
Gene:PDCD2
Gene Synonym:
Exon (2)395..637
Gene:PDCD2
Gene Synonym:
Exon (3)638..769
Gene:PDCD2
Gene Synonym:
Exon (4)770..873
Gene:PDCD2
Gene Synonym:
Exon (5)874..987
Gene:PDCD2
Gene Synonym:
Exon (6)988..3133
Gene:PDCD2
Gene Synonym:
Translation
Position Chain Variation Link
4 4 c, g dbSNP:113211980
20 20 a, g dbSNP:775062666
30 30 a, g dbSNP:186446776
46 46 c, t dbSNP:181785308
49 49 a, g dbSNP:564796099
61 61 c, t dbSNP:555386885
64 64 c, t dbSNP:534289056
74 74 c, g dbSNP:566808900
84 84 a, c dbSNP:78712376
91 91 c, g, t dbSNP:760052977
92 92 c, t dbSNP:771116468
96 96 c, t dbSNP:539613984
99 99 a, g dbSNP:532832776
101 101 c, t dbSNP:773206106
120 120 c, t dbSNP:551275548
126 126 g, t dbSNP:529662275
127 127 a, g dbSNP:567261750
148 148 a, t dbSNP:548662103
153 153 c, t dbSNP:527284090
157 157 c, t dbSNP:559964311
193 193 c, t dbSNP:773036976
195 195 c, t dbSNP:371862236
198 198 c, g dbSNP:545103128
230 230 c, t dbSNP:769150716
235 235 a, g dbSNP:749670057
237 237 a, g dbSNP:779749524
244 244 c, g dbSNP:755759947
249 249 c, t dbSNP:749923770
263 263 a, c, g dbSNP:757144594
264 264 a, c, g dbSNP:763817884
274 274 a, g dbSNP:762795976
279 279 c, t dbSNP:752501719
281 281 a, c dbSNP:61756020
282 282 a, g dbSNP:376113327
285 285 c, g dbSNP:532945174
291 291 c, t dbSNP:772313263
294 294 g, t dbSNP:189419068
295 295 c, t dbSNP:562369624
311 311 c, t dbSNP:774982075
315 315 g, t dbSNP:769349011
317 317 c, g dbSNP:74482927
318 318 g, t dbSNP:780328713
319 319 a, g dbSNP:769437764
323 323 g, t dbSNP:745536645
327 327 a, g dbSNP:200023629
331 331 g, t dbSNP:756772582
343 343 a, t dbSNP:751128316
344 344 a, g dbSNP:777682956
346 346 a, g dbSNP:555642254
354 354 c, t dbSNP:200905773
357 357 c, t dbSNP:764967878
366 366 c, t dbSNP:760914642
370 370 c, g dbSNP:750683402
372 372 g, t dbSNP:11557807
373 373 c, t dbSNP:200184000
374 374 c, t dbSNP:117413937
375 375 a, g dbSNP:774609988
385 385 a, g dbSNP:764637050
388 388 c, t dbSNP:1129634
392 392 a, g dbSNP:763390393
395 395 a, t dbSNP:148653243
397 397 g, t dbSNP:749064967
402 402 g, t dbSNP:146332925
405 405 c, t dbSNP:757512379
406 406 c, t dbSNP:751833442
409 409 c, t dbSNP:372268684
419 419 a, g dbSNP:758393282
424 424 a, g, t dbSNP:367868951
438 438 c, t dbSNP:142084425
446 446 c, g, t dbSNP:535353957
447 447 g, t dbSNP:760257138
457 457 a, c dbSNP:76108444
458 458 c, t dbSNP:772756754
463 463 c, g dbSNP:551395095
465 465 a, g dbSNP:375668108
471 471 a, t dbSNP:73258640
480 480 a, g dbSNP:773957107
482 482 c, t dbSNP:768662184
485 485 g, t dbSNP:749267353
503 503 g, t dbSNP:779926843
515 515 a, g dbSNP:769722657
518 518 a, g dbSNP:568563523
522 522 g, t dbSNP:777853006
528 528 c, g dbSNP:758688151
530 530 -, g dbSNP:145487503
531 531 g, t dbSNP:752697924
533 533 g, t dbSNP:779072921
534 534 a, g, t dbSNP:754349565
535 535 a, g dbSNP:766675033
537 537 c, t dbSNP:139143204
539 539 c, g, t dbSNP:767050564
541 541 a, c dbSNP:761545534
548 548 g, t dbSNP:372293466
549 549 c, t dbSNP:768284300
550 550 c, t dbSNP:762924182
551 551 c, g dbSNP:149555889
558 558 c, t dbSNP:561949385
565 565 a, c, g dbSNP:368569104
567 567 a, g dbSNP:772138191
569 569 a, g dbSNP:748435640
591 591 c, g dbSNP:778899901
593 593 a, c dbSNP:375620318
595 595 c, t dbSNP:755066452
602 602 a, g dbSNP:753980808
605 605 c, g dbSNP:780538358
614 614 a, g dbSNP:756658704
615 615 c, t dbSNP:201859590
616 616 a, g dbSNP:750701272
618 618 a, g dbSNP:767952037
622 622 c, g dbSNP:756790601
629 629 c, t dbSNP:772263336
636 636 a, c, g, t dbSNP:183277217
643 643 c, t dbSNP:764842993
651 651 c, t dbSNP:759350919
667 667 a, g dbSNP:776651392
668 668 a, g dbSNP:766274052
671 671 c, t dbSNP:778255010
672 672 c, t dbSNP:760484527
673 673 a, c dbSNP:773053732
676 676 c, t dbSNP:375838507
678 678 c, t dbSNP:749520124
679 679 c, t dbSNP:577424007
681 681 a, g dbSNP:769941780
693 693 g, t dbSNP:558824933
694 694 a, g dbSNP:373202680
703 703 a, g dbSNP:781338071
705 705 a, g dbSNP:770898248
708 708 -, aga dbSNP:561114246
709 709 a, g dbSNP:757772974
714 714 c, g, t dbSNP:778296317
719 719 -, t dbSNP:769614520
721 721 c, t dbSNP:758056878
728 728 c, t dbSNP:752427699
729 729 g, t dbSNP:778236042
730 730 a, g dbSNP:754486906
737 737 -, a dbSNP:745678386
751 751 a, g dbSNP:753325570
762 762 a, g dbSNP:766332437
763 763 a, g dbSNP:760583517
765 765 a, c dbSNP:192662962
766 766 a, g dbSNP:767335031
779 779 c, t dbSNP:779199451
780 780 a, t dbSNP:369266049
783 783 -, gga dbSNP:752874669
788 788 a, g dbSNP:138337157
790 790 c, g dbSNP:150472476
798 798 c, t dbSNP:758887507
799 799 a, g dbSNP:376751655
800 800 c, t dbSNP:745426165
806 806 a, c dbSNP:141160861
812 812 a, c dbSNP:757244867
815 815 a, c, t dbSNP:56926064
835 835 c, t dbSNP:763802273
836 836 a, g dbSNP:202247759
840 840 g, t dbSNP:755188301
850 850 a, c dbSNP:754029431
852 852 c, g dbSNP:766755961
853 853 -, atag dbSNP:773552634
865 865 c, t dbSNP:760804113
892 892 a, g dbSNP:774703417
899 899 c, t dbSNP:764705175
900 900 c, t dbSNP:199584824
904 904 a, c dbSNP:763226032
907 907 c, t dbSNP:775892587
909 909 c, g dbSNP:769380262
915 915 c, t dbSNP:759193086
919 919 a, g dbSNP:776080602
923 923 a, g dbSNP:140553523
935 935 a, g dbSNP:140573137
941 941 a, g dbSNP:777538268
949 949 c, g dbSNP:772112538
950 950 a, g dbSNP:747878373
960 960 c, t dbSNP:778862443
976 976 c, t dbSNP:756334058
991 991 a, t dbSNP:774403635
1008 1008 c, t dbSNP:768784755
1018 1018 a, g dbSNP:749084257
1020 1020 c, t dbSNP:775370104
1025 1025 a, c, g dbSNP:140493653
1046 1046 a, g dbSNP:747287336
1050 1050 a, c dbSNP:563527184
1067 1067 c, t dbSNP:146748595
1070 1070 a, g, t dbSNP:377003096
1076 1076 a, g dbSNP:373713795
1100 1100 a, g dbSNP:755535884
1103 1103 c, g dbSNP:754140920
1112 1112 a, t dbSNP:766767936
1121 1121 a, g dbSNP:755678073
1129 1129 -, gtaacagat dbSNP:774188663
1131 1131 a, c dbSNP:750109537
1135 1135 c, g dbSNP:188661022
1139 1139 a, c, t dbSNP:372458890
1141 1141 -, gttagg dbSNP:768179250
1141 1141 c, t dbSNP:774065733
1142 1142 -, at dbSNP:762589330
1142 1142 c, t dbSNP:142102398
1143 1143 a, c, g dbSNP:377450946
1144 1144 c, t dbSNP:769654228
1193 1193 a, c dbSNP:200568227
1227 1227 a, t dbSNP:748631044
1232 1232 c, t dbSNP:545142207
1243 1243 c, g dbSNP:575710571
1262 1262 a, g dbSNP:8770
1270 1270 -, tt dbSNP:533506308
1282 1282 a, g dbSNP:183935437
1299 1299 -, aa dbSNP:572519361
1313 1313 -, ag dbSNP:140765246
1341 1341 a, c dbSNP:3177571
1375 1375 c, g dbSNP:147181373
1395 1395 c, t dbSNP:768947596
1403 1403 a, g dbSNP:559526838
1417 1417 g, t dbSNP:17875295
1426 1426 a, g dbSNP:541353308
1457 1457 c, g dbSNP:572499054
1533 1533 a, g dbSNP:145236172
1547 1547 g, t dbSNP:539054341
1634 1634 a, c dbSNP:568907656
1693 1693 a, g dbSNP:180923611
1722 1722 a, g dbSNP:535624731
1759 1759 a, g dbSNP:568193636
1764 1764 c, t dbSNP:187959900
1824 1824 g, t dbSNP:573736418
1841 1841 c, t dbSNP:528436852
1852 1852 c, t dbSNP:756333680
1876 1876 c, g dbSNP:570769702
1881 1881 a, g dbSNP:3734763
1884 1884 a, g dbSNP:553058017
1885 1885 a, g dbSNP:574268919
1921 1921 c, t dbSNP:148421292
1922 1922 c, g dbSNP:757319671
1939 1939 a, g dbSNP:548427247
1948 1948 c, t dbSNP:765200104
1988 1988 a, c dbSNP:754790130
2001 2001 c, t dbSNP:10946282
2050 2050 a, g dbSNP:766213618
2084 2084 c, t dbSNP:543736343
2111 2111 c, t dbSNP:770634979
2112 2112 a, g dbSNP:760421463
2140 2140 c, t dbSNP:772956025
2176 2176 c, t dbSNP:572566019
2186 2186 c, t dbSNP:576035342
2189 2189 g, t dbSNP:559740957
2212 2212 c, t dbSNP:541313201
2218 2218 c, t dbSNP:185589820
2222 2222 c, t dbSNP:77376186
2240 2240 c, t dbSNP:774775206
2241 2241 a, g dbSNP:769200596
2258 2258 c, t dbSNP:541405171
2277 2277 a, g dbSNP:545361520
2338 2338 a, g dbSNP:557427499
2344 2344 a, c dbSNP:575166983
2356 2356 a, g dbSNP:556998380
2358 2358 a, g dbSNP:775845704
2367 2367 c, t dbSNP:535245864
2426 2426 a, t dbSNP:574565450
2442 2442 a, g dbSNP:367749345
2452 2452 a, g dbSNP:553163279
2455 2455 c, t dbSNP:746881516
2460 2460 c, t dbSNP:770094038
2474 2474 a, g dbSNP:59965148
2477 2477 a, t dbSNP:570732769
2486 2486 c, t dbSNP:746120487
2529 2529 -, g dbSNP:35273447
2541 2541 c, t dbSNP:144504968
2546 2546 a, g dbSNP:781444862
2550 2550 a, g dbSNP:193293086
2572 2572 c, t dbSNP:577216277
2573 2573 a, g dbSNP:12212765
2590 2590 a, g dbSNP:548659610
2595 2595 a, t dbSNP:116818292
2600 2600 a, g dbSNP:149241428
2602 2602 c, t dbSNP:6913308
2607 2607 a, g dbSNP:778785938
2608 2608 c, t dbSNP:754975298
2646 2646 g, t dbSNP:558795635
2651 2651 a, g dbSNP:753774949
2660 2660 c, t dbSNP:766305251
2664 2664 -, aa dbSNP:752399456
2682 2682 a, t dbSNP:778815174
2704 2704 a, g dbSNP:565750767
2744 2744 g, t dbSNP:115384362
2767 2767 a, t dbSNP:767182647
2770 2770 g, t dbSNP:188753274
2783 2783 a, g dbSNP:111784233
2816 2816 c, t dbSNP:376837597
2849 2849 a, g dbSNP:750880207
2914 2914 a, g dbSNP:568137860
2937 2937 c, g dbSNP:185386167
2960 2960 c, g dbSNP:536981503
2980 2980 a, g dbSNP:534773859
3021 3021 a, c dbSNP:763472894
3036 3036 a, g dbSNP:143104029
3059 3059 c, t dbSNP:770184095
3068 3068 -, tatttaaaata dbSNP:539749153
3068 3068 c, t dbSNP:759874750
3078 3078 a, g dbSNP:558869323
3098 3098 c, t dbSNP:776777804
3119 3119 a, t dbSNP:536992068
3124 3124 a, g dbSNP:192869412

Target ORF information:

RefSeq Version NM_002598
Organism Homo sapiens (human)
Definition Homo sapiens programmed cell death 2 (PDCD2), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_002598

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCTGCCG CCGGGGCCAG GCCTGTGGAG CTGGGCTTCG CCGAGTCGGC GCCGGCGTGG 
CGACTGCGCA GCGAGCAGTT CCCCAGCAAG GTGGGCGGGC GGCCGGCATG GCTGGGCGCG
GCCGGGCTGC CGGGGCCCCA GGCCCTGGCC TGCGAGCTGT GCGGCCGCCC GCTCTCCTTC
CTGCTGCAGG TGTATGCGCC GCTGCCTGGC CGCCCGGACG CCTTCCACCG CTGCATCTTC
CTCTTCTGCT GCCGCGAGCA GCCGTGCTGT GCCGGCCTGC GAGTTTTTAG GAATCAACTA
CCCAGGAAAA ACGATTTTTA CTCATATGAG CCACCTTCTG AGAATCCTCC CCCAGAAACA
GGAGAATCAG TGTGTCTCCA GCTTAAGTCT GGTGCTCATC TCTGCAGGGT TTGTGGCTGT
TTAGGCCCCA AAACGTGCTC CAGATGCCAC AAAGCATATT ACTGCAGCAA GGAGCATCAG
ACCCTAGACT GGAGATTGGG ACATAAGCAG GCTTGTGCAC AACCAGATCA TCTGGACCAT
ATAATTCCAG ACCACAACTT CCTTTTTCCA GAATTTGAAA TTGTAATAGA AACAGAAGAT
GAGATTATGC CTGAGGTTGT GGAAAAGGAA GATTACTCAG AGATTATAGG GAGCATGGGT
GAAGCACTTG AGGAAGAACT GGATTCCATG GCAAAACATG AATCCAGGGA AGATAAAATT
TTTCAGAAGT TTAAAACTCA GATAGCCCTT GAACCAGAAC AGATTCTTAG ATATGGCAGA
GGTATTGCCC CCATCTGGAT TTCTGGTGAA AATATTCCTC AAGAAAAGGA TATTCCAGAT
TGCCCCTGTG GTGCCAAGAG AATATTGGAA TTCCAGGTCA TGCCTCAGCT CCTAAACTAC
CTGAAGGCTG ACAGACTGGG CAAGAGCATT GACTGGGGCA TCCTGGCTGT CTTCACCTGT
GCTGAGAGCT GCAGCTTGGG TACTGGCTAT ACAGAAGAAT TTGTGTGGAA GCAGGATGTA
ACAGATACAC CGTAA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu09878D
Sequence Information ORF Nucleotide Sequence (Length: 687bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product programmed cell death protein 2 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL031259.1 and AJ420535.1. On Dec 10, 2010 this sequence version replaced gi:21735593. Summary: This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010]. Transcript Variant: This variant (2) differs in the 3' coding region and UTR, compared to variant 1. The resulting protein (isoform 2) has a shorter and distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ420535.1, BG721244.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962337 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCTGCCG CCGGGGCCAG GCCTGTGGAG CTGGGCTTCG CCGAGTCGGC GCCGGCGTGG 
CGACTGCGCA GCGAGCAGTT CCCCAGCAAG GTGGGCGGGC GGCCGGCATG GCTGGGCGCG
GCCGGGCTGC CGGGGCCCCA GGCCCTGGCC TGCGAGCTGT GCGGCCGCCC GCTCTCCTTC
CTGCTGCAGG TGTATGCGCC GCTGCCTGGC CGCCCGGACG CCTTCCACCG CTGCATCTTC
CTCTTCTGCT GCCGCGAGCA GCCGTGCTGT GCCGGCCTGC GAGTTTTTAG GAATCAACTA
CCCAGGAAAA ACGATTTTTA CTCATATGAG CCACCTTCTG AGAATCCTCC CCCAGAAACA
GGAGAATCAG TGTGTCTCCA GCTTAAGTCT GGTGCTCATC TCTGCAGGGT TTGTGGCTGT
TTAGGCCCCA AAACGTGCTC CAGATGCCAC AAAGCATATT ACTGCAGCAA GGAGCATCAG
ACCCTAGACT GGAGATTGGG ACATAAGCAG GCTTGTGCAC AACCAGATCA TCTGGACCAT
ATAATTCCAG ACCACAACTT CCTTTTTCCA GAATTTGAAA TTGTAATAGA AACAGAAGAT
GAGATTATGC CTGAGGTTGT GGAAAAGGAA GATTACTCAG AGATTATAGG GAGCATGGGT
AAGCAGTTTC AGGACTTCAT TCATTAA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_659005.1
CDS112..798
Misc Feature(1)514..627(+)
Exon (1)1..394
Gene:PDCD2
Gene Synonym:
Exon (2)395..637
Gene:PDCD2
Gene Synonym:
Exon (3)638..2079
Gene:PDCD2
Gene Synonym:
Translation
Position Chain Variation Link
4 4 c, g dbSNP:113211980
20 20 a, g dbSNP:775062666
30 30 a, g dbSNP:186446776
46 46 c, t dbSNP:181785308
49 49 a, g dbSNP:564796099
61 61 c, t dbSNP:555386885
64 64 c, t dbSNP:534289056
74 74 c, g dbSNP:566808900
84 84 a, c dbSNP:78712376
91 91 c, g, t dbSNP:760052977
92 92 c, t dbSNP:771116468
96 96 c, t dbSNP:539613984
99 99 a, g dbSNP:532832776
101 101 c, t dbSNP:773206106
120 120 c, t dbSNP:551275548
126 126 g, t dbSNP:529662275
127 127 a, g dbSNP:567261750
148 148 a, t dbSNP:548662103
153 153 c, t dbSNP:527284090
157 157 c, t dbSNP:559964311
193 193 c, t dbSNP:773036976
195 195 c, t dbSNP:371862236
198 198 c, g dbSNP:545103128
230 230 c, t dbSNP:769150716
235 235 a, g dbSNP:749670057
237 237 a, g dbSNP:779749524
244 244 c, g dbSNP:755759947
249 249 c, t dbSNP:749923770
263 263 a, c, g dbSNP:757144594
264 264 a, c, g dbSNP:763817884
274 274 a, g dbSNP:762795976
279 279 c, t dbSNP:752501719
281 281 a, c dbSNP:61756020
282 282 a, g dbSNP:376113327
285 285 c, g dbSNP:532945174
291 291 c, t dbSNP:772313263
294 294 g, t dbSNP:189419068
295 295 c, t dbSNP:562369624
311 311 c, t dbSNP:774982075
315 315 g, t dbSNP:769349011
317 317 c, g dbSNP:74482927
318 318 g, t dbSNP:780328713
319 319 a, g dbSNP:769437764
323 323 g, t dbSNP:745536645
327 327 a, g dbSNP:200023629
331 331 g, t dbSNP:756772582
343 343 a, t dbSNP:751128316
344 344 a, g dbSNP:777682956
346 346 a, g dbSNP:555642254
354 354 c, t dbSNP:200905773
357 357 c, t dbSNP:764967878
366 366 c, t dbSNP:760914642
370 370 c, g dbSNP:750683402
372 372 g, t dbSNP:11557807
373 373 c, t dbSNP:200184000
374 374 c, t dbSNP:117413937
375 375 a, g dbSNP:774609988
385 385 a, g dbSNP:764637050
388 388 c, t dbSNP:1129634
392 392 a, g dbSNP:763390393
395 395 a, t dbSNP:148653243
397 397 g, t dbSNP:749064967
402 402 g, t dbSNP:146332925
405 405 c, t dbSNP:757512379
406 406 c, t dbSNP:751833442
409 409 c, t dbSNP:372268684
419 419 a, g dbSNP:758393282
424 424 a, g, t dbSNP:367868951
438 438 c, t dbSNP:142084425
446 446 c, g, t dbSNP:535353957
447 447 g, t dbSNP:760257138
457 457 a, c dbSNP:76108444
458 458 c, t dbSNP:772756754
463 463 c, g dbSNP:551395095
465 465 a, g dbSNP:375668108
471 471 a, t dbSNP:73258640
480 480 a, g dbSNP:773957107
482 482 c, t dbSNP:768662184
485 485 g, t dbSNP:749267353
503 503 g, t dbSNP:779926843
515 515 a, g dbSNP:769722657
518 518 a, g dbSNP:568563523
522 522 g, t dbSNP:777853006
528 528 c, g dbSNP:758688151
530 530 -, g dbSNP:145487503
531 531 g, t dbSNP:752697924
533 533 g, t dbSNP:779072921
534 534 a, g, t dbSNP:754349565
535 535 a, g dbSNP:766675033
537 537 c, t dbSNP:139143204
539 539 c, g, t dbSNP:767050564
541 541 a, c dbSNP:761545534
548 548 g, t dbSNP:372293466
549 549 c, t dbSNP:768284300
550 550 c, t dbSNP:762924182
551 551 c, g dbSNP:149555889
558 558 c, t dbSNP:561949385
565 565 a, c, g dbSNP:368569104
567 567 a, g dbSNP:772138191
569 569 a, g dbSNP:748435640
591 591 c, g dbSNP:778899901
593 593 a, c dbSNP:375620318
595 595 c, t dbSNP:755066452
602 602 a, g dbSNP:753980808
605 605 c, g dbSNP:780538358
614 614 a, g dbSNP:756658704
615 615 c, t dbSNP:201859590
616 616 a, g dbSNP:750701272
618 618 a, g dbSNP:767952037
622 622 c, g dbSNP:756790601
629 629 c, t dbSNP:772263336
636 636 a, c, g, t dbSNP:183277217
643 643 c, t dbSNP:764842993
651 651 c, t dbSNP:759350919
667 667 a, g dbSNP:776651392
668 668 a, g dbSNP:766274052
671 671 c, t dbSNP:778255010
672 672 c, t dbSNP:760484527
673 673 a, c dbSNP:773053732
676 676 c, t dbSNP:375838507
678 678 c, t dbSNP:749520124
679 679 c, t dbSNP:577424007
681 681 a, g dbSNP:769941780
693 693 g, t dbSNP:558824933
694 694 a, g dbSNP:373202680
703 703 a, g dbSNP:781338071
705 705 a, g dbSNP:770898248
708 708 -, aga dbSNP:561114246
709 709 a, g dbSNP:757772974
714 714 c, g, t dbSNP:778296317
719 719 -, t dbSNP:769614520
721 721 c, t dbSNP:758056878
728 728 c, t dbSNP:752427699
729 729 g, t dbSNP:778236042
730 730 a, g dbSNP:754486906
737 737 -, a dbSNP:745678386
751 751 a, g dbSNP:753325570
762 762 a, g dbSNP:766332437
763 763 a, g dbSNP:760583517
765 765 a, c dbSNP:192662962
766 766 a, g dbSNP:767335031
786 786 c, t dbSNP:763115351
793 793 c, t dbSNP:187752077
805 805 a, g dbSNP:769951017
806 806 a, g dbSNP:759659044
807 807 a, g dbSNP:776632849
809 809 a, t dbSNP:79226996
814 814 a, g dbSNP:9295417
815 815 c, g dbSNP:778241526
819 819 a, g dbSNP:772585675
827 827 a, g dbSNP:748570130
833 833 a, g dbSNP:778594378
840 840 c, t dbSNP:754650921
841 841 a, g dbSNP:753371133
853 853 -, c dbSNP:750392422
869 869 c, g, t dbSNP:142807549
882 882 a, g dbSNP:777636987
905 905 c, t dbSNP:528278929
918 918 a, g dbSNP:570698065
957 957 a, g dbSNP:767274753
1029 1029 a, g dbSNP:182985220
1050 1050 c, t dbSNP:530911163
1051 1051 a, g dbSNP:12214447
1058 1058 g, t dbSNP:2072917
1066 1066 a, g dbSNP:530253401
1078 1078 g, t dbSNP:754534025
1099 1099 c, t dbSNP:559599110
1100 1100 a, g dbSNP:534352794
1111 1111 a, g dbSNP:761254972
1149 1149 c, t dbSNP:138703551
1177 1177 a, c dbSNP:558789090
1185 1185 a, g dbSNP:73793715
1215 1215 a, g dbSNP:767955864
1233 1233 a, g dbSNP:574892981
1255 1255 c, t dbSNP:556581168
1260 1260 c, t dbSNP:535115746
1264 1264 -, cctta dbSNP:548849132
1324 1324 -, tg dbSNP:774488312
1327 1327 g, t dbSNP:762237059
1357 1357 c, t dbSNP:191691000
1377 1377 c, t dbSNP:774761378
1381 1381 g, t dbSNP:115094430
1417 1417 a, g dbSNP:768985115
1421 1421 a, c dbSNP:2066954
1423 1423 c, t dbSNP:775645941
1469 1469 c, t dbSNP:371202891
1470 1470 a, g dbSNP:17860836
1503 1503 c, t dbSNP:551509286
1531 1531 c, t dbSNP:749779356
1551 1551 c, t dbSNP:143396203
1553 1553 a, g dbSNP:746990835
1573 1573 a, g dbSNP:779439052
1585 1585 a, g dbSNP:137952379
1593 1593 c, g dbSNP:750386447
1609 1609 c, t dbSNP:767494490
1626 1626 c, t dbSNP:186453867
1690 1690 c, t dbSNP:143812529
1696 1696 a, g dbSNP:373484547
1713 1713 c, g dbSNP:559652433
1721 1721 c, t dbSNP:778597560
1725 1725 a, g dbSNP:771234300
1731 1731 -, gt dbSNP:763430058
1744 1744 c, t dbSNP:183073999
1775 1775 c, t dbSNP:748879621
1844 1844 -, t dbSNP:541318061
1849 1849 c, t dbSNP:73258630
1871 1871 a, t dbSNP:12189695
1872 1872 -, gagt dbSNP:776001128
1906 1906 a, c dbSNP:561256815
1918 1918 a, c dbSNP:11557805
1930 1930 -, a dbSNP:146081543
1946 1946 g, t dbSNP:755535521
1974 1974 c, t dbSNP:532721323
1981 1981 a, t dbSNP:190814380
1984 1984 c, t dbSNP:543700179
1994 1994 -, ta dbSNP:773914040
2041 2041 a, g dbSNP:750978426
2053 2053 a, g dbSNP:148995772
2067 2067 a, c dbSNP:554846490
2068 2068 a, g dbSNP:185462539
2072 2072 c, t dbSNP:138944210

Target ORF information:

RefSeq Version NM_144781
Organism Homo sapiens (human)
Definition Homo sapiens programmed cell death 2 (PDCD2), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_144781

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCTGCCG CCGGGGCCAG GCCTGTGGAG CTGGGCTTCG CCGAGTCGGC GCCGGCGTGG 
CGACTGCGCA GCGAGCAGTT CCCCAGCAAG GTGGGCGGGC GGCCGGCATG GCTGGGCGCG
GCCGGGCTGC CGGGGCCCCA GGCCCTGGCC TGCGAGCTGT GCGGCCGCCC GCTCTCCTTC
CTGCTGCAGG TGTATGCGCC GCTGCCTGGC CGCCCGGACG CCTTCCACCG CTGCATCTTC
CTCTTCTGCT GCCGCGAGCA GCCGTGCTGT GCCGGCCTGC GAGTTTTTAG GAATCAACTA
CCCAGGAAAA ACGATTTTTA CTCATATGAG CCACCTTCTG AGAATCCTCC CCCAGAAACA
GGAGAATCAG TGTGTCTCCA GCTTAAGTCT GGTGCTCATC TCTGCAGGGT TTGTGGCTGT
TTAGGCCCCA AAACGTGCTC CAGATGCCAC AAAGCATATT ACTGCAGCAA GGAGCATCAG
ACCCTAGACT GGAGATTGGG ACATAAGCAG GCTTGTGCAC AACCAGATCA TCTGGACCAT
ATAATTCCAG ACCACAACTT CCTTTTTCCA GAATTTGAAA TTGTAATAGA AACAGAAGAT
GAGATTATGC CTGAGGTTGT GGAAAAGGAA GATTACTCAG AGATTATAGG GAGCATGGGT
AAGCAGTTTC AGGACTTCAT TCATTAA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu09885D
Sequence Information ORF Nucleotide Sequence (Length: 666bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product programmed cell death protein 2 isoform 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL031259.1, AW966881.1 and AJ420535.1. Summary: This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010]. Transcript Variant: This variant (3) differs in the 3' coding region and UTR, compared to variant 1. The resulting protein (isoform 3) has a shorter and distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AW966881.1, AW967505.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962337 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCTGCCG CCGGGGCCAG GCCTGTGGAG CTGGGCTTCG CCGAGTCGGC GCCGGCGTGG 
CGACTGCGCA GCGAGCAGTT CCCCAGCAAG GTGGGCGGGC GGCCGGCATG GCTGGGCGCG
GCCGGGCTGC CGGGGCCCCA GGCCCTGGCC TGCGAGCTGT GCGGCCGCCC GCTCTCCTTC
CTGCTGCAGG TGTATGCGCC GCTGCCTGGC CGCCCGGACG CCTTCCACCG CTGCATCTTC
CTCTTCTGCT GCCGCGAGCA GCCGTGCTGT GCCGGCCTGC GAGTTTTTAG GAATCAACTA
CCCAGGAAAA ACGATTTTTA CTCATATGAG CCACCTTCTG AGAATCCTCC CCCAGAAACA
GGAGAATCAG TGTGTCTCCA GCTTAAGTCT GGTGCTCATC TCTGCAGGGT TTGTGGCTGT
TTAGGCCCCA AAACGTGCTC CAGATGCCAC AAAGCATATT ACTGCAGCAA GGAGCATCAG
ACCCTAGACT GGAGATTGGG ACATAAGCAG GCTTGTGCAC AACCAGATCA TCTGGACCAT
ATAATTCCAG ACCACAACTT CCTTTTTCCA GAATTTGAAA TTGTAATAGA AACAGAAGAT
GAGATTATGC CTGAGGTTGT GGAAAAGGAA GATTACTCAG AGATTATAGG GAGCATGGGG
ATATAA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_001186390.1
CDS112..777
Misc Feature(1)514..627(+)
Exon (1)1..394
Gene:PDCD2
Gene Synonym:
Exon (2)395..637
Gene:PDCD2
Gene Synonym:
Exon (3)638..769
Gene:PDCD2
Gene Synonym:
Exon (4)770..1288
Gene:PDCD2
Gene Synonym:
Translation
Position Chain Variation Link
4 4 c, g dbSNP:113211980
20 20 a, g dbSNP:775062666
30 30 a, g dbSNP:186446776
46 46 c, t dbSNP:181785308
49 49 a, g dbSNP:564796099
61 61 c, t dbSNP:555386885
64 64 c, t dbSNP:534289056
74 74 c, g dbSNP:566808900
84 84 a, c dbSNP:78712376
91 91 c, g, t dbSNP:760052977
92 92 c, t dbSNP:771116468
96 96 c, t dbSNP:539613984
99 99 a, g dbSNP:532832776
101 101 c, t dbSNP:773206106
120 120 c, t dbSNP:551275548
126 126 g, t dbSNP:529662275
127 127 a, g dbSNP:567261750
148 148 a, t dbSNP:548662103
153 153 c, t dbSNP:527284090
157 157 c, t dbSNP:559964311
193 193 c, t dbSNP:773036976
195 195 c, t dbSNP:371862236
198 198 c, g dbSNP:545103128
230 230 c, t dbSNP:769150716
235 235 a, g dbSNP:749670057
237 237 a, g dbSNP:779749524
244 244 c, g dbSNP:755759947
249 249 c, t dbSNP:749923770
263 263 a, c, g dbSNP:757144594
264 264 a, c, g dbSNP:763817884
274 274 a, g dbSNP:762795976
279 279 c, t dbSNP:752501719
281 281 a, c dbSNP:61756020
282 282 a, g dbSNP:376113327
285 285 c, g dbSNP:532945174
291 291 c, t dbSNP:772313263
294 294 g, t dbSNP:189419068
295 295 c, t dbSNP:562369624
311 311 c, t dbSNP:774982075
315 315 g, t dbSNP:769349011
317 317 c, g dbSNP:74482927
318 318 g, t dbSNP:780328713
319 319 a, g dbSNP:769437764
323 323 g, t dbSNP:745536645
327 327 a, g dbSNP:200023629
331 331 g, t dbSNP:756772582
343 343 a, t dbSNP:751128316
344 344 a, g dbSNP:777682956
346 346 a, g dbSNP:555642254
354 354 c, t dbSNP:200905773
357 357 c, t dbSNP:764967878
366 366 c, t dbSNP:760914642
370 370 c, g dbSNP:750683402
372 372 g, t dbSNP:11557807
373 373 c, t dbSNP:200184000
374 374 c, t dbSNP:117413937
375 375 a, g dbSNP:774609988
385 385 a, g dbSNP:764637050
388 388 c, t dbSNP:1129634
392 392 a, g dbSNP:763390393
395 395 a, t dbSNP:148653243
397 397 g, t dbSNP:749064967
402 402 g, t dbSNP:146332925
405 405 c, t dbSNP:757512379
406 406 c, t dbSNP:751833442
409 409 c, t dbSNP:372268684
419 419 a, g dbSNP:758393282
424 424 a, g, t dbSNP:367868951
438 438 c, t dbSNP:142084425
446 446 c, g, t dbSNP:535353957
447 447 g, t dbSNP:760257138
457 457 a, c dbSNP:76108444
458 458 c, t dbSNP:772756754
463 463 c, g dbSNP:551395095
465 465 a, g dbSNP:375668108
471 471 a, t dbSNP:73258640
480 480 a, g dbSNP:773957107
482 482 c, t dbSNP:768662184
485 485 g, t dbSNP:749267353
503 503 g, t dbSNP:779926843
515 515 a, g dbSNP:769722657
518 518 a, g dbSNP:568563523
522 522 g, t dbSNP:777853006
528 528 c, g dbSNP:758688151
530 530 -, g dbSNP:145487503
531 531 g, t dbSNP:752697924
533 533 g, t dbSNP:779072921
534 534 a, g, t dbSNP:754349565
535 535 a, g dbSNP:766675033
537 537 c, t dbSNP:139143204
539 539 c, g, t dbSNP:767050564
541 541 a, c dbSNP:761545534
548 548 g, t dbSNP:372293466
549 549 c, t dbSNP:768284300
550 550 c, t dbSNP:762924182
551 551 c, g dbSNP:149555889
558 558 c, t dbSNP:561949385
565 565 a, c, g dbSNP:368569104
567 567 a, g dbSNP:772138191
569 569 a, g dbSNP:748435640
591 591 c, g dbSNP:778899901
593 593 a, c dbSNP:375620318
595 595 c, t dbSNP:755066452
602 602 a, g dbSNP:753980808
605 605 c, g dbSNP:780538358
614 614 a, g dbSNP:756658704
615 615 c, t dbSNP:201859590
616 616 a, g dbSNP:750701272
618 618 a, g dbSNP:767952037
622 622 c, g dbSNP:756790601
629 629 c, t dbSNP:772263336
636 636 a, c, g, t dbSNP:183277217
643 643 c, t dbSNP:764842993
651 651 c, t dbSNP:759350919
667 667 a, g dbSNP:776651392
668 668 a, g dbSNP:766274052
671 671 c, t dbSNP:778255010
672 672 c, t dbSNP:760484527
673 673 a, c dbSNP:773053732
676 676 c, t dbSNP:375838507
678 678 c, t dbSNP:749520124
679 679 c, t dbSNP:577424007
681 681 a, g dbSNP:769941780
693 693 g, t dbSNP:558824933
694 694 a, g dbSNP:373202680
703 703 a, g dbSNP:781338071
705 705 a, g dbSNP:770898248
708 708 -, aga dbSNP:561114246
709 709 a, g dbSNP:757772974
714 714 c, g, t dbSNP:778296317
719 719 -, t dbSNP:769614520
721 721 c, t dbSNP:758056878
728 728 c, t dbSNP:752427699
729 729 g, t dbSNP:778236042
730 730 a, g dbSNP:754486906
737 737 -, a dbSNP:745678386
751 751 a, g dbSNP:753325570
762 762 a, g dbSNP:766332437
763 763 a, g dbSNP:760583517
765 765 a, c dbSNP:192662962
766 766 a, g dbSNP:767335031
782 782 a, g dbSNP:779439052
794 794 a, g dbSNP:137952379
802 802 c, g dbSNP:750386447
818 818 c, t dbSNP:767494490
835 835 c, t dbSNP:186453867
899 899 c, t dbSNP:143812529
905 905 a, g dbSNP:373484547
922 922 c, g dbSNP:559652433
930 930 c, t dbSNP:778597560
934 934 a, g dbSNP:771234300
940 940 -, gt dbSNP:763430058
953 953 c, t dbSNP:183073999
984 984 c, t dbSNP:748879621
1053 1053 -, t dbSNP:541318061
1058 1058 c, t dbSNP:73258630
1080 1080 a, t dbSNP:12189695
1081 1081 -, gagt dbSNP:776001128
1115 1115 a, c dbSNP:561256815
1127 1127 a, c dbSNP:11557805
1139 1139 -, a dbSNP:146081543
1155 1155 g, t dbSNP:755535521
1183 1183 c, t dbSNP:532721323
1190 1190 a, t dbSNP:190814380
1193 1193 c, t dbSNP:543700179
1203 1203 -, ta dbSNP:773914040
1250 1250 a, g dbSNP:750978426
1262 1262 a, g dbSNP:148995772
1276 1276 a, c dbSNP:554846490
1277 1277 a, g dbSNP:185462539
1281 1281 c, t dbSNP:138944210

Target ORF information:

RefSeq Version NM_001199461
Organism Homo sapiens (human)
Definition Homo sapiens programmed cell death 2 (PDCD2), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_001199461

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCTGCCG CCGGGGCCAG GCCTGTGGAG CTGGGCTTCG CCGAGTCGGC GCCGGCGTGG 
CGACTGCGCA GCGAGCAGTT CCCCAGCAAG GTGGGCGGGC GGCCGGCATG GCTGGGCGCG
GCCGGGCTGC CGGGGCCCCA GGCCCTGGCC TGCGAGCTGT GCGGCCGCCC GCTCTCCTTC
CTGCTGCAGG TGTATGCGCC GCTGCCTGGC CGCCCGGACG CCTTCCACCG CTGCATCTTC
CTCTTCTGCT GCCGCGAGCA GCCGTGCTGT GCCGGCCTGC GAGTTTTTAG GAATCAACTA
CCCAGGAAAA ACGATTTTTA CTCATATGAG CCACCTTCTG AGAATCCTCC CCCAGAAACA
GGAGAATCAG TGTGTCTCCA GCTTAAGTCT GGTGCTCATC TCTGCAGGGT TTGTGGCTGT
TTAGGCCCCA AAACGTGCTC CAGATGCCAC AAAGCATATT ACTGCAGCAA GGAGCATCAG
ACCCTAGACT GGAGATTGGG ACATAAGCAG GCTTGTGCAC AACCAGATCA TCTGGACCAT
ATAATTCCAG ACCACAACTT CCTTTTTCCA GAATTTGAAA TTGTAATAGA AACAGAAGAT
GAGATTATGC CTGAGGTTGT GGAAAAGGAA GATTACTCAG AGATTATAGG GAGCATGGGG
ATATAA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu12040D
Sequence Information ORF Nucleotide Sequence (Length: 588bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product programmed cell death protein 2 isoform 5
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK297343.1, AL031259.1 and AJ420535.1. Summary: This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010]. Transcript Variant: This variant (5) uses an alternate in-frame splice site in the 5' coding region and differs in the 3' coding region and UTR, compared to variant 1. The resulting protein (isoform 5) is shorter and has a distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK297343.1, BX396302.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1968540, SAMEA1970526 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
ATGGCTGCCG CCGGGGCCAG GCCTGTGGAG CTGGGCTTCG CCGAGTCGGC GCCGGCGTGG 
CGACTGCGCA GCGAGCAGTT CCCCAGCAAG GTGTATGCGC CGCTGCCTGG CCGCCCGGAC
GCCTTCCACC GCTGCATCTT CCTCTTCTGC TGCCGCGAGC AGCCGTGCTG TGCCGGCCTG
CGAGTTTTTA GGAATCAACT ACCCAGGAAA AACGATTTTT ACTCATATGA GCCACCTTCT
GAGAATCCTC CCCCAGAAAC AGGAGAATCA GTGTGTCTCC AGCTTAAGTC TGGTGCTCAT
CTCTGCAGGG TTTGTGGCTG TTTAGGCCCC AAAACGTGCT CCAGATGCCA CAAAGCATAT
TACTGCAGCA AGGAGCATCA GACCCTAGAC TGGAGATTGG GACATAAGCA GGCTTGTGCA
CAACCAGATC ATCTGGACCA TATAATTCCA GACCACAACT TCCTTTTTCC AGAATTTGAA
ATTGTAATAG AAACAGAAGA TGAGATTATG CCTGAGGTTG TGGAAAAGGA AGATTACTCA
GAGATTATAG GGAGCATGGG TAAGCAGTTT CAGGACTTCA TTCATTAA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_001186392.1
CDS74..661
Misc Feature(1)377..490(+)
Exon (1)1..163
Gene:PDCD2
Gene Synonym:
Exon (2)164..257
Gene:PDCD2
Gene Synonym:
Exon (3)258..500
Gene:PDCD2
Gene Synonym:
Exon (4)501..1942
Gene:PDCD2
Gene Synonym:
Translation
Position Chain Variation Link
8 8 c, t dbSNP:181785308
11 11 a, g dbSNP:564796099
23 23 c, t dbSNP:555386885
26 26 c, t dbSNP:534289056
36 36 c, g dbSNP:566808900
46 46 a, c dbSNP:78712376
53 53 c, g, t dbSNP:760052977
54 54 c, t dbSNP:771116468
58 58 c, t dbSNP:539613984
61 61 a, g dbSNP:532832776
63 63 c, t dbSNP:773206106
82 82 c, t dbSNP:551275548
88 88 g, t dbSNP:529662275
89 89 a, g dbSNP:567261750
110 110 a, t dbSNP:548662103
115 115 c, t dbSNP:527284090
119 119 c, t dbSNP:559964311
155 155 c, t dbSNP:773036976
157 157 c, t dbSNP:371862236
160 160 c, g dbSNP:545103128
174 174 c, t dbSNP:774982075
178 178 g, t dbSNP:769349011
180 180 c, g dbSNP:74482927
181 181 g, t dbSNP:780328713
182 182 a, g dbSNP:769437764
186 186 g, t dbSNP:745536645
190 190 a, g dbSNP:200023629
194 194 g, t dbSNP:756772582
206 206 a, t dbSNP:751128316
207 207 a, g dbSNP:777682956
209 209 a, g dbSNP:555642254
217 217 c, t dbSNP:200905773
220 220 c, t dbSNP:764967878
229 229 c, t dbSNP:760914642
233 233 c, g dbSNP:750683402
235 235 g, t dbSNP:11557807
236 236 c, t dbSNP:200184000
237 237 c, t dbSNP:117413937
238 238 a, g dbSNP:774609988
248 248 a, g dbSNP:764637050
251 251 c, t dbSNP:1129634
255 255 a, g dbSNP:763390393
258 258 a, t dbSNP:148653243
260 260 g, t dbSNP:749064967
265 265 g, t dbSNP:146332925
268 268 c, t dbSNP:757512379
269 269 c, t dbSNP:751833442
272 272 c, t dbSNP:372268684
282 282 a, g dbSNP:758393282
287 287 a, g, t dbSNP:367868951
301 301 c, t dbSNP:142084425
309 309 c, g, t dbSNP:535353957
310 310 g, t dbSNP:760257138
320 320 a, c dbSNP:76108444
321 321 c, t dbSNP:772756754
326 326 c, g dbSNP:551395095
328 328 a, g dbSNP:375668108
334 334 a, t dbSNP:73258640
343 343 a, g dbSNP:773957107
345 345 c, t dbSNP:768662184
348 348 g, t dbSNP:749267353
366 366 g, t dbSNP:779926843
378 378 a, g dbSNP:769722657
381 381 a, g dbSNP:568563523
385 385 g, t dbSNP:777853006
391 391 c, g dbSNP:758688151
393 393 -, g dbSNP:145487503
394 394 g, t dbSNP:752697924
396 396 g, t dbSNP:779072921
397 397 a, g, t dbSNP:754349565
398 398 a, g dbSNP:766675033
400 400 c, t dbSNP:139143204
402 402 c, g, t dbSNP:767050564
404 404 a, c dbSNP:761545534
411 411 g, t dbSNP:372293466
412 412 c, t dbSNP:768284300
413 413 c, t dbSNP:762924182
414 414 c, g dbSNP:149555889
421 421 c, t dbSNP:561949385
428 428 a, c, g dbSNP:368569104
430 430 a, g dbSNP:772138191
432 432 a, g dbSNP:748435640
454 454 c, g dbSNP:778899901
456 456 a, c dbSNP:375620318
458 458 c, t dbSNP:755066452
465 465 a, g dbSNP:753980808
468 468 c, g dbSNP:780538358
477 477 a, g dbSNP:756658704
478 478 c, t dbSNP:201859590
479 479 a, g dbSNP:750701272
481 481 a, g dbSNP:767952037
485 485 c, g dbSNP:756790601
492 492 c, t dbSNP:772263336
499 499 a, c, g, t dbSNP:183277217
506 506 c, t dbSNP:764842993
514 514 c, t dbSNP:759350919
530 530 a, g dbSNP:776651392
531 531 a, g dbSNP:766274052
534 534 c, t dbSNP:778255010
535 535 c, t dbSNP:760484527
536 536 a, c dbSNP:773053732
539 539 c, t dbSNP:375838507
541 541 c, t dbSNP:749520124
542 542 c, t dbSNP:577424007
544 544 a, g dbSNP:769941780
556 556 g, t dbSNP:558824933
557 557 a, g dbSNP:373202680
566 566 a, g dbSNP:781338071
568 568 a, g dbSNP:770898248
571 571 -, aga dbSNP:561114246
572 572 a, g dbSNP:757772974
577 577 c, g, t dbSNP:778296317
582 582 -, t dbSNP:769614520
584 584 c, t dbSNP:758056878
591 591 c, t dbSNP:752427699
592 592 g, t dbSNP:778236042
593 593 a, g dbSNP:754486906
600 600 -, a dbSNP:745678386
614 614 a, g dbSNP:753325570
625 625 a, g dbSNP:766332437
626 626 a, g dbSNP:760583517
628 628 a, c dbSNP:192662962
629 629 a, g dbSNP:767335031
649 649 c, t dbSNP:763115351
656 656 c, t dbSNP:187752077
668 668 a, g dbSNP:769951017
669 669 a, g dbSNP:759659044
670 670 a, g dbSNP:776632849
672 672 a, t dbSNP:79226996
677 677 a, g dbSNP:9295417
678 678 c, g dbSNP:778241526
682 682 a, g dbSNP:772585675
690 690 a, g dbSNP:748570130
696 696 a, g dbSNP:778594378
703 703 c, t dbSNP:754650921
704 704 a, g dbSNP:753371133
716 716 -, c dbSNP:750392422
732 732 c, g, t dbSNP:142807549
745 745 a, g dbSNP:777636987
768 768 c, t dbSNP:528278929
781 781 a, g dbSNP:570698065
820 820 a, g dbSNP:767274753
892 892 a, g dbSNP:182985220
913 913 c, t dbSNP:530911163
914 914 a, g dbSNP:12214447
921 921 g, t dbSNP:2072917
929 929 a, g dbSNP:530253401
941 941 g, t dbSNP:754534025
962 962 c, t dbSNP:559599110
963 963 a, g dbSNP:534352794
974 974 a, g dbSNP:761254972
1012 1012 c, t dbSNP:138703551
1040 1040 a, c dbSNP:558789090
1048 1048 a, g dbSNP:73793715
1078 1078 a, g dbSNP:767955864
1096 1096 a, g dbSNP:574892981
1118 1118 c, t dbSNP:556581168
1123 1123 c, t dbSNP:535115746
1127 1127 -, cctta dbSNP:548849132
1187 1187 -, tg dbSNP:774488312
1190 1190 g, t dbSNP:762237059
1220 1220 c, t dbSNP:191691000
1240 1240 c, t dbSNP:774761378
1244 1244 g, t dbSNP:115094430
1280 1280 a, g dbSNP:768985115
1284 1284 a, c dbSNP:2066954
1286 1286 c, t dbSNP:775645941
1332 1332 c, t dbSNP:371202891
1333 1333 a, g dbSNP:17860836
1366 1366 c, t dbSNP:551509286
1394 1394 c, t dbSNP:749779356
1414 1414 c, t dbSNP:143396203
1416 1416 a, g dbSNP:746990835
1436 1436 a, g dbSNP:779439052
1448 1448 a, g dbSNP:137952379
1456 1456 c, g dbSNP:750386447
1472 1472 c, t dbSNP:767494490
1489 1489 c, t dbSNP:186453867
1553 1553 c, t dbSNP:143812529
1559 1559 a, g dbSNP:373484547
1576 1576 c, g dbSNP:559652433
1584 1584 c, t dbSNP:778597560
1588 1588 a, g dbSNP:771234300
1594 1594 -, gt dbSNP:763430058
1607 1607 c, t dbSNP:183073999
1638 1638 c, t dbSNP:748879621
1707 1707 -, t dbSNP:541318061
1712 1712 c, t dbSNP:73258630
1734 1734 a, t dbSNP:12189695
1735 1735 -, gagt dbSNP:776001128
1769 1769 a, c dbSNP:561256815
1781 1781 a, c dbSNP:11557805
1793 1793 -, a dbSNP:146081543
1809 1809 g, t dbSNP:755535521
1837 1837 c, t dbSNP:532721323
1844 1844 a, t dbSNP:190814380
1847 1847 c, t dbSNP:543700179
1857 1857 -, ta dbSNP:773914040
1904 1904 a, g dbSNP:750978426
1916 1916 a, g dbSNP:148995772
1930 1930 a, c dbSNP:554846490
1931 1931 a, g dbSNP:185462539
1935 1935 c, t dbSNP:138944210

Target ORF information:

RefSeq Version NM_001199463
Organism Homo sapiens (human)
Definition Homo sapiens programmed cell death 2 (PDCD2), transcript variant 5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_001199463

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGCTGCCG CCGGGGCCAG GCCTGTGGAG CTGGGCTTCG CCGAGTCGGC GCCGGCGTGG 
CGACTGCGCA GCGAGCAGTT CCCCAGCAAG GTGTATGCGC CGCTGCCTGG CCGCCCGGAC
GCCTTCCACC GCTGCATCTT CCTCTTCTGC TGCCGCGAGC AGCCGTGCTG TGCCGGCCTG
CGAGTTTTTA GGAATCAACT ACCCAGGAAA AACGATTTTT ACTCATATGA GCCACCTTCT
GAGAATCCTC CCCCAGAAAC AGGAGAATCA GTGTGTCTCC AGCTTAAGTC TGGTGCTCAT
CTCTGCAGGG TTTGTGGCTG TTTAGGCCCC AAAACGTGCT CCAGATGCCA CAAAGCATAT
TACTGCAGCA AGGAGCATCA GACCCTAGAC TGGAGATTGG GACATAAGCA GGCTTGTGCA
CAACCAGATC ATCTGGACCA TATAATTCCA GACCACAACT TCCTTTTTCC AGAATTTGAA
ATTGTAATAG AAACAGAAGA TGAGATTATG CCTGAGGTTG TGGAAAAGGA AGATTACTCA
GAGATTATAG GGAGCATGGG TAAGCAGTTT CAGGACTTCA TTCATTAA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu10456D
Sequence Information ORF Nucleotide Sequence (Length: 567bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product programmed cell death protein 2 isoform 6
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK297343.1, BX385363.2, AL031259.1 and AJ420535.1. Summary: This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010]. Transcript Variant: This variant (6) uses an alternate in-frame splice site in the 5' coding region and differs in the 3' coding region and UTR, compared to variant 1. The resulting protein (isoform 6) is shorter and has a distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX385363.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
ATGGCTGCCG CCGGGGCCAG GCCTGTGGAG CTGGGCTTCG CCGAGTCGGC GCCGGCGTGG 
CGACTGCGCA GCGAGCAGTT CCCCAGCAAG GTGTATGCGC CGCTGCCTGG CCGCCCGGAC
GCCTTCCACC GCTGCATCTT CCTCTTCTGC TGCCGCGAGC AGCCGTGCTG TGCCGGCCTG
CGAGTTTTTA GGAATCAACT ACCCAGGAAA AACGATTTTT ACTCATATGA GCCACCTTCT
GAGAATCCTC CCCCAGAAAC AGGAGAATCA GTGTGTCTCC AGCTTAAGTC TGGTGCTCAT
CTCTGCAGGG TTTGTGGCTG TTTAGGCCCC AAAACGTGCT CCAGATGCCA CAAAGCATAT
TACTGCAGCA AGGAGCATCA GACCCTAGAC TGGAGATTGG GACATAAGCA GGCTTGTGCA
CAACCAGATC ATCTGGACCA TATAATTCCA GACCACAACT TCCTTTTTCC AGAATTTGAA
ATTGTAATAG AAACAGAAGA TGAGATTATG CCTGAGGTTG TGGAAAAGGA AGATTACTCA
GAGATTATAG GGAGCATGGG GATATAA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_001186393.1
CDS74..640
Misc Feature(1)377..490(+)
Exon (1)1..163
Gene:PDCD2
Gene Synonym:
Exon (2)164..257
Gene:PDCD2
Gene Synonym:
Exon (3)258..500
Gene:PDCD2
Gene Synonym:
Exon (4)501..632
Gene:PDCD2
Gene Synonym:
Exon (5)633..1151
Gene:PDCD2
Gene Synonym:
Translation
Position Chain Variation Link
8 8 c, t dbSNP:181785308
11 11 a, g dbSNP:564796099
23 23 c, t dbSNP:555386885
26 26 c, t dbSNP:534289056
36 36 c, g dbSNP:566808900
46 46 a, c dbSNP:78712376
53 53 c, g, t dbSNP:760052977
54 54 c, t dbSNP:771116468
58 58 c, t dbSNP:539613984
61 61 a, g dbSNP:532832776
63 63 c, t dbSNP:773206106
82 82 c, t dbSNP:551275548
88 88 g, t dbSNP:529662275
89 89 a, g dbSNP:567261750
110 110 a, t dbSNP:548662103
115 115 c, t dbSNP:527284090
119 119 c, t dbSNP:559964311
155 155 c, t dbSNP:773036976
157 157 c, t dbSNP:371862236
160 160 c, g dbSNP:545103128
174 174 c, t dbSNP:774982075
178 178 g, t dbSNP:769349011
180 180 c, g dbSNP:74482927
181 181 g, t dbSNP:780328713
182 182 a, g dbSNP:769437764
186 186 g, t dbSNP:745536645
190 190 a, g dbSNP:200023629
194 194 g, t dbSNP:756772582
206 206 a, t dbSNP:751128316
207 207 a, g dbSNP:777682956
209 209 a, g dbSNP:555642254
217 217 c, t dbSNP:200905773
220 220 c, t dbSNP:764967878
229 229 c, t dbSNP:760914642
233 233 c, g dbSNP:750683402
235 235 g, t dbSNP:11557807
236 236 c, t dbSNP:200184000
237 237 c, t dbSNP:117413937
238 238 a, g dbSNP:774609988
248 248 a, g dbSNP:764637050
251 251 c, t dbSNP:1129634
255 255 a, g dbSNP:763390393
258 258 a, t dbSNP:148653243
260 260 g, t dbSNP:749064967
265 265 g, t dbSNP:146332925
268 268 c, t dbSNP:757512379
269 269 c, t dbSNP:751833442
272 272 c, t dbSNP:372268684
282 282 a, g dbSNP:758393282
287 287 a, g, t dbSNP:367868951
301 301 c, t dbSNP:142084425
309 309 c, g, t dbSNP:535353957
310 310 g, t dbSNP:760257138
320 320 a, c dbSNP:76108444
321 321 c, t dbSNP:772756754
326 326 c, g dbSNP:551395095
328 328 a, g dbSNP:375668108
334 334 a, t dbSNP:73258640
343 343 a, g dbSNP:773957107
345 345 c, t dbSNP:768662184
348 348 g, t dbSNP:749267353
366 366 g, t dbSNP:779926843
378 378 a, g dbSNP:769722657
381 381 a, g dbSNP:568563523
385 385 g, t dbSNP:777853006
391 391 c, g dbSNP:758688151
393 393 -, g dbSNP:145487503
394 394 g, t dbSNP:752697924
396 396 g, t dbSNP:779072921
397 397 a, g, t dbSNP:754349565
398 398 a, g dbSNP:766675033
400 400 c, t dbSNP:139143204
402 402 c, g, t dbSNP:767050564
404 404 a, c dbSNP:761545534
411 411 g, t dbSNP:372293466
412 412 c, t dbSNP:768284300
413 413 c, t dbSNP:762924182
414 414 c, g dbSNP:149555889
421 421 c, t dbSNP:561949385
428 428 a, c, g dbSNP:368569104
430 430 a, g dbSNP:772138191
432 432 a, g dbSNP:748435640
454 454 c, g dbSNP:778899901
456 456 a, c dbSNP:375620318
458 458 c, t dbSNP:755066452
465 465 a, g dbSNP:753980808
468 468 c, g dbSNP:780538358
477 477 a, g dbSNP:756658704
478 478 c, t dbSNP:201859590
479 479 a, g dbSNP:750701272
481 481 a, g dbSNP:767952037
485 485 c, g dbSNP:756790601
492 492 c, t dbSNP:772263336
499 499 a, c, g, t dbSNP:183277217
506 506 c, t dbSNP:764842993
514 514 c, t dbSNP:759350919
530 530 a, g dbSNP:776651392
531 531 a, g dbSNP:766274052
534 534 c, t dbSNP:778255010
535 535 c, t dbSNP:760484527
536 536 a, c dbSNP:773053732
539 539 c, t dbSNP:375838507
541 541 c, t dbSNP:749520124
542 542 c, t dbSNP:577424007
544 544 a, g dbSNP:769941780
556 556 g, t dbSNP:558824933
557 557 a, g dbSNP:373202680
566 566 a, g dbSNP:781338071
568 568 a, g dbSNP:770898248
571 571 -, aga dbSNP:561114246
572 572 a, g dbSNP:757772974
577 577 c, g, t dbSNP:778296317
582 582 -, t dbSNP:769614520
584 584 c, t dbSNP:758056878
591 591 c, t dbSNP:752427699
592 592 g, t dbSNP:778236042
593 593 a, g dbSNP:754486906
600 600 -, a dbSNP:745678386
614 614 a, g dbSNP:753325570
625 625 a, g dbSNP:766332437
626 626 a, g dbSNP:760583517
628 628 a, c dbSNP:192662962
629 629 a, g dbSNP:767335031
645 645 a, g dbSNP:779439052
657 657 a, g dbSNP:137952379
665 665 c, g dbSNP:750386447
681 681 c, t dbSNP:767494490
698 698 c, t dbSNP:186453867
762 762 c, t dbSNP:143812529
768 768 a, g dbSNP:373484547
785 785 c, g dbSNP:559652433
793 793 c, t dbSNP:778597560
797 797 a, g dbSNP:771234300
803 803 -, gt dbSNP:763430058
816 816 c, t dbSNP:183073999
847 847 c, t dbSNP:748879621
916 916 -, t dbSNP:541318061
921 921 c, t dbSNP:73258630
943 943 a, t dbSNP:12189695
944 944 -, gagt dbSNP:776001128
978 978 a, c dbSNP:561256815
990 990 a, c dbSNP:11557805
1002 1002 -, a dbSNP:146081543
1018 1018 g, t dbSNP:755535521
1046 1046 c, t dbSNP:532721323
1053 1053 a, t dbSNP:190814380
1056 1056 c, t dbSNP:543700179
1066 1066 -, ta dbSNP:773914040
1113 1113 a, g dbSNP:750978426
1125 1125 a, g dbSNP:148995772
1139 1139 a, c dbSNP:554846490
1140 1140 a, g dbSNP:185462539
1144 1144 c, t dbSNP:138944210

Target ORF information:

RefSeq Version NM_001199464
Organism Homo sapiens (human)
Definition Homo sapiens programmed cell death 2 (PDCD2), transcript variant 6, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_001199464

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGCTGCCG CCGGGGCCAG GCCTGTGGAG CTGGGCTTCG CCGAGTCGGC GCCGGCGTGG 
CGACTGCGCA GCGAGCAGTT CCCCAGCAAG GTGTATGCGC CGCTGCCTGG CCGCCCGGAC
GCCTTCCACC GCTGCATCTT CCTCTTCTGC TGCCGCGAGC AGCCGTGCTG TGCCGGCCTG
CGAGTTTTTA GGAATCAACT ACCCAGGAAA AACGATTTTT ACTCATATGA GCCACCTTCT
GAGAATCCTC CCCCAGAAAC AGGAGAATCA GTGTGTCTCC AGCTTAAGTC TGGTGCTCAT
CTCTGCAGGG TTTGTGGCTG TTTAGGCCCC AAAACGTGCT CCAGATGCCA CAAAGCATAT
TACTGCAGCA AGGAGCATCA GACCCTAGAC TGGAGATTGG GACATAAGCA GGCTTGTGCA
CAACCAGATC ATCTGGACCA TATAATTCCA GACCACAACT TCCTTTTTCC AGAATTTGAA
ATTGTAATAG AAACAGAAGA TGAGATTATG CCTGAGGTTG TGGAAAAGGA AGATTACTCA
GAGATTATAG GGAGCATGGG GATATAA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu09435D
Sequence Information ORF Nucleotide Sequence (Length: 936bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product programmed cell death protein 2 isoform 4
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC351104.1, AY948416.1 and AK055180.1. Summary: This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010]. Transcript Variant: This variant (4) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The resulting protein (isoform 4) is shorter, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY948416.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCTGCCG CCGGGGCCAG GCCTGTGGAG CTGGGCTTCG CCGAGTCGGC GCCGGCGTGG 
CGACTGCGCA GCGAGCAGTT CCCCAGCAAG GTGTATGCGC CGCTGCCTGG CCGCCCGGAC
GCCTTCCACC GCTGCATCTT CCTCTTCTGC TGCCGCGAGC AGCCGTGCTG TGCCGGCCTG
CGAGTTTTTA GGAATCAACT ACCCAGGAAA AACGATTTTT ACTCATATGA GCCACCTTCT
GAGAATCCTC CCCCAGAAAC AGGAGAATCA GTGTGTCTCC AGCTTAAGTC TGGTGCTCAT
CTCTGCAGGG TTTGTGGCTG TTTAGGCCCC AAAACGTGCT CCAGATGCCA CAAAGCATAT
TACTGCAGCA AGGAGCATCA GACCCTAGAC TGGAGATTGG GACATAAGCA GGCTTGTGCA
CAACCAGATC ATCTGGACCA TATAATTCCA GACCACAACT TCCTTTTTCC AGAATTTGAA
ATTGTAATAG AAACAGAAGA TGAGATTATG CCTGAGGTTG TGGAAAAGGA AGATTACTCA
GAGATTATAG GGAGCATGGG TGAAGCACTT GAGGAAGAAC TGGATTCCAT GGCAAAACAT
GAATCCAGGG AAGATAAAAT TTTTCAGAAG TTTAAAACTC AGATAGCCCT TGAACCAGAA
CAGATTCTTA GATATGGCAG AGGTATTGCC CCCATCTGGA TTTCTGGTGA AAATATTCCT
CAAGAAAAGG ATATTCCAGA TTGCCCCTGT GGTGCCAAGA GAATATTGGA ATTCCAGGTC
ATGCCTCAGC TCCTAAACTA CCTGAAGGCT GACAGACTGG GCAAGAGCAT TGACTGGGGC
ATCCTGGCTG TCTTCACCTG TGCTGAGAGC TGCAGCTTGG GTACTGGCTA TACAGAAGAA
TTTGTGTGGA AGCAGGATGT AACAGATACA CCGTAA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_001186391.1
CDS74..1009
Misc Feature(1)377..490(+)
Misc Feature(2)521..997(+)
Exon (1)1..163
Gene:PDCD2
Gene Synonym:
Exon (2)164..257
Gene:PDCD2
Gene Synonym:
Exon (3)258..500
Gene:PDCD2
Gene Synonym:
Exon (4)501..632
Gene:PDCD2
Gene Synonym:
Exon (5)633..736
Gene:PDCD2
Gene Synonym:
Exon (6)737..850
Gene:PDCD2
Gene Synonym:
Exon (7)851..2996
Gene:PDCD2
Gene Synonym:
Translation
Position Chain Variation Link
8 8 c, t dbSNP:181785308
11 11 a, g dbSNP:564796099
23 23 c, t dbSNP:555386885
26 26 c, t dbSNP:534289056
36 36 c, g dbSNP:566808900
46 46 a, c dbSNP:78712376
53 53 c, g, t dbSNP:760052977
54 54 c, t dbSNP:771116468
58 58 c, t dbSNP:539613984
61 61 a, g dbSNP:532832776
63 63 c, t dbSNP:773206106
82 82 c, t dbSNP:551275548
88 88 g, t dbSNP:529662275
89 89 a, g dbSNP:567261750
110 110 a, t dbSNP:548662103
115 115 c, t dbSNP:527284090
119 119 c, t dbSNP:559964311
155 155 c, t dbSNP:773036976
157 157 c, t dbSNP:371862236
160 160 c, g dbSNP:545103128
174 174 c, t dbSNP:774982075
178 178 g, t dbSNP:769349011
180 180 c, g dbSNP:74482927
181 181 g, t dbSNP:780328713
182 182 a, g dbSNP:769437764
186 186 g, t dbSNP:745536645
190 190 a, g dbSNP:200023629
194 194 g, t dbSNP:756772582
206 206 a, t dbSNP:751128316
207 207 a, g dbSNP:777682956
209 209 a, g dbSNP:555642254
217 217 c, t dbSNP:200905773
220 220 c, t dbSNP:764967878
229 229 c, t dbSNP:760914642
233 233 c, g dbSNP:750683402
235 235 g, t dbSNP:11557807
236 236 c, t dbSNP:200184000
237 237 c, t dbSNP:117413937
238 238 a, g dbSNP:774609988
248 248 a, g dbSNP:764637050
251 251 c, t dbSNP:1129634
255 255 a, g dbSNP:763390393
258 258 a, t dbSNP:148653243
260 260 g, t dbSNP:749064967
265 265 g, t dbSNP:146332925
268 268 c, t dbSNP:757512379
269 269 c, t dbSNP:751833442
272 272 c, t dbSNP:372268684
282 282 a, g dbSNP:758393282
287 287 a, g, t dbSNP:367868951
301 301 c, t dbSNP:142084425
309 309 c, g, t dbSNP:535353957
310 310 g, t dbSNP:760257138
320 320 a, c dbSNP:76108444
321 321 c, t dbSNP:772756754
326 326 c, g dbSNP:551395095
328 328 a, g dbSNP:375668108
334 334 a, t dbSNP:73258640
343 343 a, g dbSNP:773957107
345 345 c, t dbSNP:768662184
348 348 g, t dbSNP:749267353
366 366 g, t dbSNP:779926843
378 378 a, g dbSNP:769722657
381 381 a, g dbSNP:568563523
385 385 g, t dbSNP:777853006
391 391 c, g dbSNP:758688151
393 393 -, g dbSNP:145487503
394 394 g, t dbSNP:752697924
396 396 g, t dbSNP:779072921
397 397 a, g, t dbSNP:754349565
398 398 a, g dbSNP:766675033
400 400 c, t dbSNP:139143204
402 402 c, g, t dbSNP:767050564
404 404 a, c dbSNP:761545534
411 411 g, t dbSNP:372293466
412 412 c, t dbSNP:768284300
413 413 c, t dbSNP:762924182
414 414 c, g dbSNP:149555889
421 421 c, t dbSNP:561949385
428 428 a, c, g dbSNP:368569104
430 430 a, g dbSNP:772138191
432 432 a, g dbSNP:748435640
454 454 c, g dbSNP:778899901
456 456 a, c dbSNP:375620318
458 458 c, t dbSNP:755066452
465 465 a, g dbSNP:753980808
468 468 c, g dbSNP:780538358
477 477 a, g dbSNP:756658704
478 478 c, t dbSNP:201859590
479 479 a, g dbSNP:750701272
481 481 a, g dbSNP:767952037
485 485 c, g dbSNP:756790601
492 492 c, t dbSNP:772263336
499 499 a, c, g, t dbSNP:183277217
506 506 c, t dbSNP:764842993
514 514 c, t dbSNP:759350919
530 530 a, g dbSNP:776651392
531 531 a, g dbSNP:766274052
534 534 c, t dbSNP:778255010
535 535 c, t dbSNP:760484527
536 536 a, c dbSNP:773053732
539 539 c, t dbSNP:375838507
541 541 c, t dbSNP:749520124
542 542 c, t dbSNP:577424007
544 544 a, g dbSNP:769941780
556 556 g, t dbSNP:558824933
557 557 a, g dbSNP:373202680
566 566 a, g dbSNP:781338071
568 568 a, g dbSNP:770898248
571 571 -, aga dbSNP:561114246
572 572 a, g dbSNP:757772974
577 577 c, g, t dbSNP:778296317
582 582 -, t dbSNP:769614520
584 584 c, t dbSNP:758056878
591 591 c, t dbSNP:752427699
592 592 g, t dbSNP:778236042
593 593 a, g dbSNP:754486906
600 600 -, a dbSNP:745678386
614 614 a, g dbSNP:753325570
625 625 a, g dbSNP:766332437
626 626 a, g dbSNP:760583517
628 628 a, c dbSNP:192662962
629 629 a, g dbSNP:767335031
642 642 c, t dbSNP:779199451
643 643 a, t dbSNP:369266049
646 646 -, gga dbSNP:752874669
651 651 a, g dbSNP:138337157
653 653 c, g dbSNP:150472476
661 661 c, t dbSNP:758887507
662 662 a, g dbSNP:376751655
663 663 c, t dbSNP:745426165
669 669 a, c dbSNP:141160861
675 675 a, c dbSNP:757244867
678 678 a, c, t dbSNP:56926064
698 698 c, t dbSNP:763802273
699 699 a, g dbSNP:202247759
703 703 g, t dbSNP:755188301
713 713 a, c dbSNP:754029431
715 715 c, g dbSNP:766755961
716 716 -, atag dbSNP:773552634
728 728 c, t dbSNP:760804113
755 755 a, g dbSNP:774703417
762 762 c, t dbSNP:764705175
763 763 c, t dbSNP:199584824
767 767 a, c dbSNP:763226032
770 770 c, t dbSNP:775892587
772 772 c, g dbSNP:769380262
778 778 c, t dbSNP:759193086
782 782 a, g dbSNP:776080602
786 786 a, g dbSNP:140553523
798 798 a, g dbSNP:140573137
804 804 a, g dbSNP:777538268
812 812 c, g dbSNP:772112538
813 813 a, g dbSNP:747878373
823 823 c, t dbSNP:778862443
839 839 c, t dbSNP:756334058
854 854 a, t dbSNP:774403635
871 871 c, t dbSNP:768784755
881 881 a, g dbSNP:749084257
883 883 c, t dbSNP:775370104
888 888 a, c, g dbSNP:140493653
909 909 a, g dbSNP:747287336
913 913 a, c dbSNP:563527184
930 930 c, t dbSNP:146748595
933 933 a, g, t dbSNP:377003096
939 939 a, g dbSNP:373713795
963 963 a, g dbSNP:755535884
966 966 c, g dbSNP:754140920
975 975 a, t dbSNP:766767936
984 984 a, g dbSNP:755678073
992 992 -, gtaacagat dbSNP:774188663
994 994 a, c dbSNP:750109537
998 998 c, g dbSNP:188661022
1002 1002 a, c, t dbSNP:372458890
1004 1004 -, gttagg dbSNP:768179250
1004 1004 c, t dbSNP:774065733
1005 1005 -, at dbSNP:762589330
1005 1005 c, t dbSNP:142102398
1006 1006 a, c, g dbSNP:377450946
1007 1007 c, t dbSNP:769654228
1056 1056 a, c dbSNP:200568227
1090 1090 a, t dbSNP:748631044
1095 1095 c, t dbSNP:545142207
1106 1106 c, g dbSNP:575710571
1125 1125 a, g dbSNP:8770
1133 1133 -, tt dbSNP:533506308
1145 1145 a, g dbSNP:183935437
1162 1162 -, aa dbSNP:572519361
1176 1176 -, ag dbSNP:140765246
1204 1204 a, c dbSNP:3177571
1238 1238 c, g dbSNP:147181373
1258 1258 c, t dbSNP:768947596
1266 1266 a, g dbSNP:559526838
1280 1280 g, t dbSNP:17875295
1289 1289 a, g dbSNP:541353308
1320 1320 c, g dbSNP:572499054
1396 1396 a, g dbSNP:145236172
1410 1410 g, t dbSNP:539054341
1497 1497 a, c dbSNP:568907656
1556 1556 a, g dbSNP:180923611
1585 1585 a, g dbSNP:535624731
1622 1622 a, g dbSNP:568193636
1627 1627 c, t dbSNP:187959900
1687 1687 g, t dbSNP:573736418
1704 1704 c, t dbSNP:528436852
1715 1715 c, t dbSNP:756333680
1739 1739 c, g dbSNP:570769702
1744 1744 a, g dbSNP:3734763
1747 1747 a, g dbSNP:553058017
1748 1748 a, g dbSNP:574268919
1784 1784 c, t dbSNP:148421292
1785 1785 c, g dbSNP:757319671
1802 1802 a, g dbSNP:548427247
1811 1811 c, t dbSNP:765200104
1851 1851 a, c dbSNP:754790130
1864 1864 c, t dbSNP:10946282
1913 1913 a, g dbSNP:766213618
1947 1947 c, t dbSNP:543736343
1974 1974 c, t dbSNP:770634979
1975 1975 a, g dbSNP:760421463
2003 2003 c, t dbSNP:772956025
2039 2039 c, t dbSNP:572566019
2049 2049 c, t dbSNP:576035342
2052 2052 g, t dbSNP:559740957
2075 2075 c, t dbSNP:541313201
2081 2081 c, t dbSNP:185589820
2085 2085 c, t dbSNP:77376186
2103 2103 c, t dbSNP:774775206
2104 2104 a, g dbSNP:769200596
2121 2121 c, t dbSNP:541405171
2140 2140 a, g dbSNP:545361520
2201 2201 a, g dbSNP:557427499
2207 2207 a, c dbSNP:575166983
2219 2219 a, g dbSNP:556998380
2221 2221 a, g dbSNP:775845704
2230 2230 c, t dbSNP:535245864
2289 2289 a, t dbSNP:574565450
2305 2305 a, g dbSNP:367749345
2315 2315 a, g dbSNP:553163279
2318 2318 c, t dbSNP:746881516
2323 2323 c, t dbSNP:770094038
2337 2337 a, g dbSNP:59965148
2340 2340 a, t dbSNP:570732769
2349 2349 c, t dbSNP:746120487
2392 2392 -, g dbSNP:35273447
2404 2404 c, t dbSNP:144504968
2409 2409 a, g dbSNP:781444862
2413 2413 a, g dbSNP:193293086
2435 2435 c, t dbSNP:577216277
2436 2436 a, g dbSNP:12212765
2453 2453 a, g dbSNP:548659610
2458 2458 a, t dbSNP:116818292
2463 2463 a, g dbSNP:149241428
2465 2465 c, t dbSNP:6913308
2470 2470 a, g dbSNP:778785938
2471 2471 c, t dbSNP:754975298
2509 2509 g, t dbSNP:558795635
2514 2514 a, g dbSNP:753774949
2523 2523 c, t dbSNP:766305251
2527 2527 -, aa dbSNP:752399456
2545 2545 a, t dbSNP:778815174
2567 2567 a, g dbSNP:565750767
2607 2607 g, t dbSNP:115384362
2630 2630 a, t dbSNP:767182647
2633 2633 g, t dbSNP:188753274
2646 2646 a, g dbSNP:111784233
2679 2679 c, t dbSNP:376837597
2712 2712 a, g dbSNP:750880207
2777 2777 a, g dbSNP:568137860
2800 2800 c, g dbSNP:185386167
2823 2823 c, g dbSNP:536981503
2843 2843 a, g dbSNP:534773859
2884 2884 a, c dbSNP:763472894
2899 2899 a, g dbSNP:143104029
2922 2922 c, t dbSNP:770184095
2931 2931 -, tatttaaaata dbSNP:539749153
2931 2931 c, t dbSNP:759874750
2941 2941 a, g dbSNP:558869323
2961 2961 c, t dbSNP:776777804
2982 2982 a, t dbSNP:536992068
2987 2987 a, g dbSNP:192869412

Target ORF information:

RefSeq Version NM_001199462
Organism Homo sapiens (human)
Definition Homo sapiens programmed cell death 2 (PDCD2), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_001199462

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCTGCCG CCGGGGCCAG GCCTGTGGAG CTGGGCTTCG CCGAGTCGGC GCCGGCGTGG 
CGACTGCGCA GCGAGCAGTT CCCCAGCAAG GTGTATGCGC CGCTGCCTGG CCGCCCGGAC
GCCTTCCACC GCTGCATCTT CCTCTTCTGC TGCCGCGAGC AGCCGTGCTG TGCCGGCCTG
CGAGTTTTTA GGAATCAACT ACCCAGGAAA AACGATTTTT ACTCATATGA GCCACCTTCT
GAGAATCCTC CCCCAGAAAC AGGAGAATCA GTGTGTCTCC AGCTTAAGTC TGGTGCTCAT
CTCTGCAGGG TTTGTGGCTG TTTAGGCCCC AAAACGTGCT CCAGATGCCA CAAAGCATAT
TACTGCAGCA AGGAGCATCA GACCCTAGAC TGGAGATTGG GACATAAGCA GGCTTGTGCA
CAACCAGATC ATCTGGACCA TATAATTCCA GACCACAACT TCCTTTTTCC AGAATTTGAA
ATTGTAATAG AAACAGAAGA TGAGATTATG CCTGAGGTTG TGGAAAAGGA AGATTACTCA
GAGATTATAG GGAGCATGGG TGAAGCACTT GAGGAAGAAC TGGATTCCAT GGCAAAACAT
GAATCCAGGG AAGATAAAAT TTTTCAGAAG TTTAAAACTC AGATAGCCCT TGAACCAGAA
CAGATTCTTA GATATGGCAG AGGTATTGCC CCCATCTGGA TTTCTGGTGA AAATATTCCT
CAAGAAAAGG ATATTCCAGA TTGCCCCTGT GGTGCCAAGA GAATATTGGA ATTCCAGGTC
ATGCCTCAGC TCCTAAACTA CCTGAAGGCT GACAGACTGG GCAAGAGCAT TGACTGGGGC
ATCCTGGCTG TCTTCACCTG TGCTGAGAGC TGCAGCTTGG GTACTGGCTA TACAGAAGAA
TTTGTGTGGA AGCAGGATGT AACAGATACA CCGTAA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.