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PRRX2 paired related homeobox 2 [Homo sapiens (human)]

Gene Symbol PRRX2
Entrez Gene ID 51450
Full Name paired related homeobox 2
Synonyms PMX2, PRX2
General protein information
Preferred Names
paired mesoderm homeobox protein 2
Names
paired mesoderm homeobox protein 2
PRX-2
paired-related homeobox protein 2
paired-like homeodomain protein PRX2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9q34.1

Summary The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

604675

Disorder Html:





The following PRRX2 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PRRX2 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu67943 XM_011518771 PREDICTED: Homo sapiens paired related homeobox 2 (PRRX2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $99
OHu67944 XM_011518772 PREDICTED: Homo sapiens paired related homeobox 2 (PRRX2), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $99
OHu30413 NM_016307 Homo sapiens paired related homeobox 2 (PRRX2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$199

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu67943
Accession Version XM_011518771.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 528bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product paired mesoderm homeobox protein 2 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008470.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
ATGCATTCCA AGGAGACAGA AAACAGTGAG TGTCCCAGCC CGGGGCGCGG TAGCGCCGCC 
AAGCGGAAGA AGAAGCAGCG GCGGAACCGC ACCACGTTCA ACAGCAGCCA ACTGCAGGCG
CTGGAGCGCG TGTTCGAGCG CACGCACTAC CCCGACGCCT TTGTGCGCGA GGAGCTTGCC
CGGCGCGTCA ACCTCAGCGA GGCGCGCGTT CAGGTCTGGT TTCAGAACCG CCGCGCCAAG
TTCCGCAGGA ATGAAAGGGC CATGCTGGCC AGCCGCTCTG CCTCGCTGCT CAAGTCCTAC
AGCCAGGAGG CCGCCATCGA GCAGCCCGTG GCTCCCCGGC CCACCGCCCT GAGTCCAGAT
TATCTCTCCT GGACAGCCTC GTCCCCCTAC AGCACAGTGC CACCCTACAG CCCTGGGAGC
TCAGGCCCCG CAACCCCAGG GGTCAACATG GCCAACAGCA TCGCCAGCCT CCGTCTCAAG
GCCAAGGAGT TCAGCCTGCA CCACAGCCAG GTGCCTACGG TGAACTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011517073.1
CDS16..543
Misc Feature(1)106..270(+)
Misc Feature(2)106..264(+)
Misc Feature(3)109..252(+)
Misc Feature(4)454..516(+)
Translation
Position Chain Variation Link
27 27 a, g dbSNP:769015916
44 44 a, c dbSNP:751921861
45 45 a, g dbSNP:564891395
53 53 g, t dbSNP:767772157
56 56 c, t dbSNP:777230786
57 57 g, t dbSNP:754567369
73 73 a, g, t dbSNP:527354835
74 74 c, t dbSNP:752216948
75 75 a, c, t dbSNP:370204978
78 78 a, g dbSNP:35865713
79 79 c, t dbSNP:746928887
80 80 g, t dbSNP:770826522
84 84 a, g dbSNP:201665194
88 88 a, c dbSNP:201179051
93 93 c, g dbSNP:149764500
97 97 c, t dbSNP:769856483
98 98 g, t dbSNP:775573934
102 102 c, t dbSNP:376858807
108 108 c, t dbSNP:768713520
110 110 c, t dbSNP:529534534
120 120 c, g dbSNP:774909161
121 121 a, g dbSNP:762197918
122 122 a, g dbSNP:370267786
126 126 a, g dbSNP:750705637
129 129 a, g dbSNP:759266648
138 138 a, g dbSNP:764916399
140 140 a, g dbSNP:537937463
143 143 -, c dbSNP:781559184
143 143 c, g, t dbSNP:373913153
144 144 c, t dbSNP:758038591
151 151 a, g dbSNP:777417092
153 153 a, g dbSNP:751553829
154 154 c, t dbSNP:546912518
157 157 a, g dbSNP:781060799
158 158 c, t dbSNP:745608136
171 171 a, c, g dbSNP:756329628
183 183 c, t dbSNP:749511698
186 186 a, g dbSNP:199887986
192 192 g, t dbSNP:774394592
194 194 c, t dbSNP:569564205
196 196 c, t dbSNP:748715547
198 198 a, g dbSNP:772420049
199 199 a, c dbSNP:773632263
201 201 a, c dbSNP:537836904
202 202 a, g dbSNP:766838695
205 205 a, g dbSNP:775348667
207 207 c, t dbSNP:376061825
214 214 c, g dbSNP:202114136
221 221 c, g dbSNP:763744669
245 245 a, g dbSNP:747544751
249 249 a, c, t dbSNP:538411699
251 251 -, c dbSNP:755828117
252 252 a, c dbSNP:777113929
254 254 a, g dbSNP:762716963
258 258 c, t dbSNP:763795890
259 259 c, t dbSNP:773912196
270 270 a, g dbSNP:761167838
272 272 a, g dbSNP:767037621
274 274 g, t dbSNP:545291388
276 276 c, t dbSNP:556265818
278 278 c, t dbSNP:760586243
290 290 a, g, t dbSNP:766187907
291 291 c, t dbSNP:755197464
295 295 c, g dbSNP:145779250
296 296 c, g dbSNP:140591214
299 299 c, t dbSNP:144448846
300 300 a, g dbSNP:146603979
309 309 a, g dbSNP:547352299
311 311 c, t dbSNP:777876138
314 314 a, g dbSNP:567572265
319 319 c, g dbSNP:771515908
324 324 g, t dbSNP:781713116
327 327 c, t dbSNP:746163957
331 331 a, g dbSNP:765923715
333 333 c, t dbSNP:768366620
334 334 a, g dbSNP:773930013
344 344 a, t dbSNP:761498521
345 345 a, g dbSNP:771533497
346 346 g, t dbSNP:772733281
347 347 c, t dbSNP:141327412
348 348 c, t dbSNP:766238887
352 352 c, g dbSNP:753647365
357 357 c, t dbSNP:759386453
360 360 c, g dbSNP:765077601
364 364 c, g dbSNP:143393943
366 366 a, g dbSNP:758622935
368 368 a, g dbSNP:201217720
370 370 c, g, t dbSNP:751649295
371 371 c, t dbSNP:781739454
377 377 a, c dbSNP:148368723
380 380 a, t dbSNP:569824624
381 381 a, c, t dbSNP:372702758
383 383 c, g dbSNP:140111310
395 395 c, t dbSNP:771719938
396 396 a, g dbSNP:553709679
400 400 a, c, g, t dbSNP:552481765
402 402 c, t dbSNP:759487699
415 415 c, g dbSNP:763963937
422 422 a, t dbSNP:530773145
425 425 c, g dbSNP:762092376
437 437 c, t dbSNP:150293718
442 442 c, t dbSNP:750493450
444 444 c, t dbSNP:544099756
445 445 a, g, t dbSNP:566612578
457 457 a, g dbSNP:755437873
461 461 a, g dbSNP:779219560
469 469 a, g dbSNP:746715077
471 471 c, t dbSNP:756852568
477 477 c, t dbSNP:138042846
478 478 a, g dbSNP:745318451
484 484 c, g dbSNP:769631139
487 487 c, t dbSNP:202233874
488 488 a, g dbSNP:201083423
492 492 c, g dbSNP:768608876
498 498 c, t dbSNP:200632042
499 499 -, a dbSNP:779650417
500 500 a, g dbSNP:762161505
504 504 a, g dbSNP:772358017
509 509 c, g dbSNP:773183325
533 533 c, t dbSNP:143523637
534 534 a, c, g dbSNP:373951160
540 540 c, t dbSNP:760016044
545 545 -, gtccagt dbSNP:748845072
545 545 a, g dbSNP:765610431
555 555 a, c dbSNP:28428946
559 559 a, g dbSNP:756907451
564 564 c, g dbSNP:780765136
568 568 c, t dbSNP:370487741
569 569 a, g dbSNP:549073959
570 570 c, t dbSNP:779397611
589 589 a, g dbSNP:116237845
606 606 c, t dbSNP:575443811
619 619 a, g dbSNP:373341887
644 644 a, g dbSNP:142417382
669 669 a, g dbSNP:756253077
677 677 a, c, g dbSNP:2241898
688 688 a, g dbSNP:780394237
694 694 c, t dbSNP:1051445
701 701 a, g dbSNP:370014709
705 705 c, g dbSNP:28441121
749 749 c, t dbSNP:535567000
759 759 c, t dbSNP:555876693
810 810 g, t dbSNP:73627671
847 847 -, t dbSNP:552520403
854 854 -, a, t dbSNP:36093277
861 861 c, t dbSNP:10988483

Target ORF information:

RefSeq Version XM_011518771
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens paired related homeobox 2 (PRRX2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011518771

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGCATTCCA AGGAGACAGA AAACAGTGAG TGTCCCAGCC CGGGGCGCGG TAGCGCCGCC 
AAGCGGAAGA AGAAGCAGCG GCGGAACCGC ACCACGTTCA ACAGCAGCCA ACTGCAGGCG
CTGGAGCGCG TGTTCGAGCG CACGCACTAC CCCGACGCCT TTGTGCGCGA GGAGCTTGCC
CGGCGCGTCA ACCTCAGCGA GGCGCGCGTT CAGGTCTGGT TTCAGAACCG CCGCGCCAAG
TTCCGCAGGA ATGAAAGGGC CATGCTGGCC AGCCGCTCTG CCTCGCTGCT CAAGTCCTAC
AGCCAGGAGG CCGCCATCGA GCAGCCCGTG GCTCCCCGGC CCACCGCCCT GAGTCCAGAT
TATCTCTCCT GGACAGCCTC GTCCCCCTAC AGCACAGTGC CACCCTACAG CCCTGGGAGC
TCAGGCCCCG CAACCCCAGG GGTCAACATG GCCAACAGCA TCGCCAGCCT CCGTCTCAAG
GCCAAGGAGT TCAGCCTGCA CCACAGCCAG GTGCCTACGG TGAACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu67944
Accession Version XM_011518772.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product paired mesoderm homeobox protein 2 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008470.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
ATGCTTGGAG GTGAGTGTCC CAGCCCGGGG CGCGGTAGCG CCGCCAAGCG GAAGAAGAAG 
CAGCGGCGGA ACCGCACCAC GTTCAACAGC AGCCAACTGC AGGCGCTGGA GCGCGTGTTC
GAGCGCACGC ACTACCCCGA CGCCTTTGTG CGCGAGGAGC TTGCCCGGCG CGTCAACCTC
AGCGAGGCGC GCGTTCAGGT CTGGTTTCAG AACCGCCGCG CCAAGTTCCG CAGGAATGAA
AGGGCCATGC TGGCCAGCCG CTCTGCCTCG CTGCTCAAGT CCTACAGCCA GGAGGCCGCC
ATCGAGCAGC CCGTGGCTCC CCGGCCCACC GCCCTGAGTC CAGATTATCT CTCCTGGACA
GCCTCGTCCC CCTACAGCAC AGTGCCACCC TACAGCCCTG GGAGCTCAGG CCCCGCAACC
CCAGGGGTCA ACATGGCCAA CAGCATCGCC AGCCTCCGTC TCAAGGCCAA GGAGTTCAGC
CTGCACCACA GCCAGGTGCC TACGGTGAAC TGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011517074.1
CDS825..1337
Misc Feature(1)900..1064(+)
Misc Feature(2)900..1058(+)
Misc Feature(3)903..1046(+)
Misc Feature(4)1248..1310(+)
Translation
Position Chain Variation Link
3 3 a, g dbSNP:79636645
34 34 a, c dbSNP:546428269
36 36 c, t dbSNP:759854519
60 60 c, t dbSNP:560433567
95 95 g, t dbSNP:542415428
96 96 -, a dbSNP:570433842
122 122 c, t dbSNP:73670154
123 123 a, g dbSNP:759058896
129 129 a, g dbSNP:115631935
150 150 c, t dbSNP:537418513
200 200 c, t dbSNP:189717281
201 201 a, g dbSNP:374900086
292 292 c, t dbSNP:7032080
367 367 c, t dbSNP:533892503
416 416 a, g dbSNP:117061940
421 421 c, t dbSNP:752631975
464 464 c, t dbSNP:79686347
476 476 a, g dbSNP:181358542
480 480 a, g dbSNP:76729941
498 498 c, t dbSNP:575909989
514 514 c, t dbSNP:544236017
518 518 c, t dbSNP:144777736
541 541 -, ga dbSNP:540931149
579 579 c, t dbSNP:578030115
582 582 a, c dbSNP:540769241
593 593 a, g dbSNP:757404612
616 616 c, g dbSNP:562166689
673 673 a, c dbSNP:146712990
677 677 a, g dbSNP:529132225
682 682 c, t dbSNP:569357561
691 691 c, g dbSNP:185916649
717 717 c, g dbSNP:538209050
723 723 c, g, t dbSNP:552454688
739 739 a, g dbSNP:562609421
766 766 a, g dbSNP:565256534
800 800 c, t dbSNP:551043161
807 807 c, t dbSNP:780132724
829 829 g, t dbSNP:571268822
838 838 a, c dbSNP:751921861
839 839 a, g dbSNP:564891395
847 847 g, t dbSNP:767772157
850 850 c, t dbSNP:777230786
851 851 g, t dbSNP:754567369
867 867 a, g, t dbSNP:527354835
868 868 c, t dbSNP:752216948
869 869 a, c, t dbSNP:370204978
872 872 a, g dbSNP:35865713
873 873 c, t dbSNP:746928887
874 874 g, t dbSNP:770826522
878 878 a, g dbSNP:201665194
882 882 a, c dbSNP:201179051
887 887 c, g dbSNP:149764500
891 891 c, t dbSNP:769856483
892 892 g, t dbSNP:775573934
896 896 c, t dbSNP:376858807
902 902 c, t dbSNP:768713520
904 904 c, t dbSNP:529534534
914 914 c, g dbSNP:774909161
915 915 a, g dbSNP:762197918
916 916 a, g dbSNP:370267786
920 920 a, g dbSNP:750705637
923 923 a, g dbSNP:759266648
932 932 a, g dbSNP:764916399
934 934 a, g dbSNP:537937463
937 937 -, c dbSNP:781559184
937 937 c, g, t dbSNP:373913153
938 938 c, t dbSNP:758038591
945 945 a, g dbSNP:777417092
947 947 a, g dbSNP:751553829
948 948 c, t dbSNP:546912518
951 951 a, g dbSNP:781060799
952 952 c, t dbSNP:745608136
965 965 a, c, g dbSNP:756329628
977 977 c, t dbSNP:749511698
980 980 a, g dbSNP:199887986
986 986 g, t dbSNP:774394592
988 988 c, t dbSNP:569564205
990 990 c, t dbSNP:748715547
992 992 a, g dbSNP:772420049
993 993 a, c dbSNP:773632263
995 995 a, c dbSNP:537836904
996 996 a, g dbSNP:766838695
999 999 a, g dbSNP:775348667
1001 1001 c, t dbSNP:376061825
1008 1008 c, g dbSNP:202114136
1015 1015 c, g dbSNP:763744669
1039 1039 a, g dbSNP:747544751
1043 1043 a, c, t dbSNP:538411699
1045 1045 -, c dbSNP:755828117
1046 1046 a, c dbSNP:777113929
1048 1048 a, g dbSNP:762716963
1052 1052 c, t dbSNP:763795890
1053 1053 c, t dbSNP:773912196
1064 1064 a, g dbSNP:761167838
1066 1066 a, g dbSNP:767037621
1068 1068 g, t dbSNP:545291388
1070 1070 c, t dbSNP:556265818
1072 1072 c, t dbSNP:760586243
1084 1084 a, g, t dbSNP:766187907
1085 1085 c, t dbSNP:755197464
1089 1089 c, g dbSNP:145779250
1090 1090 c, g dbSNP:140591214
1093 1093 c, t dbSNP:144448846
1094 1094 a, g dbSNP:146603979
1103 1103 a, g dbSNP:547352299
1105 1105 c, t dbSNP:777876138
1108 1108 a, g dbSNP:567572265
1113 1113 c, g dbSNP:771515908
1118 1118 g, t dbSNP:781713116
1121 1121 c, t dbSNP:746163957
1125 1125 a, g dbSNP:765923715
1127 1127 c, t dbSNP:768366620
1128 1128 a, g dbSNP:773930013
1138 1138 a, t dbSNP:761498521
1139 1139 a, g dbSNP:771533497
1140 1140 g, t dbSNP:772733281
1141 1141 c, t dbSNP:141327412
1142 1142 c, t dbSNP:766238887
1146 1146 c, g dbSNP:753647365
1151 1151 c, t dbSNP:759386453
1154 1154 c, g dbSNP:765077601
1158 1158 c, g dbSNP:143393943
1160 1160 a, g dbSNP:758622935
1162 1162 a, g dbSNP:201217720
1164 1164 c, g, t dbSNP:751649295
1165 1165 c, t dbSNP:781739454
1171 1171 a, c dbSNP:148368723
1174 1174 a, t dbSNP:569824624
1175 1175 a, c, t dbSNP:372702758
1177 1177 c, g dbSNP:140111310
1189 1189 c, t dbSNP:771719938
1190 1190 a, g dbSNP:553709679
1194 1194 a, c, g, t dbSNP:552481765
1196 1196 c, t dbSNP:759487699
1209 1209 c, g dbSNP:763963937
1216 1216 a, t dbSNP:530773145
1219 1219 c, g dbSNP:762092376
1231 1231 c, t dbSNP:150293718
1236 1236 c, t dbSNP:750493450
1238 1238 c, t dbSNP:544099756
1239 1239 a, g, t dbSNP:566612578
1251 1251 a, g dbSNP:755437873
1255 1255 a, g dbSNP:779219560
1263 1263 a, g dbSNP:746715077
1265 1265 c, t dbSNP:756852568
1271 1271 c, t dbSNP:138042846
1272 1272 a, g dbSNP:745318451
1278 1278 c, g dbSNP:769631139
1281 1281 c, t dbSNP:202233874
1282 1282 a, g dbSNP:201083423
1286 1286 c, g dbSNP:768608876
1292 1292 c, t dbSNP:200632042
1293 1293 -, a dbSNP:779650417
1294 1294 a, g dbSNP:762161505
1298 1298 a, g dbSNP:772358017
1303 1303 c, g dbSNP:773183325
1327 1327 c, t dbSNP:143523637
1328 1328 a, c, g dbSNP:373951160
1334 1334 c, t dbSNP:760016044
1339 1339 -, gtccagt dbSNP:748845072
1339 1339 a, g dbSNP:765610431
1349 1349 a, c dbSNP:28428946
1353 1353 a, g dbSNP:756907451
1358 1358 c, g dbSNP:780765136
1362 1362 c, t dbSNP:370487741
1363 1363 a, g dbSNP:549073959
1364 1364 c, t dbSNP:779397611
1383 1383 a, g dbSNP:116237845
1400 1400 c, t dbSNP:575443811
1413 1413 a, g dbSNP:373341887
1438 1438 a, g dbSNP:142417382
1463 1463 a, g dbSNP:756253077
1471 1471 a, c, g dbSNP:2241898
1482 1482 a, g dbSNP:780394237
1488 1488 c, t dbSNP:1051445
1495 1495 a, g dbSNP:370014709
1499 1499 c, g dbSNP:28441121
1543 1543 c, t dbSNP:535567000
1553 1553 c, t dbSNP:555876693
1604 1604 g, t dbSNP:73627671
1641 1641 -, t dbSNP:552520403
1648 1648 -, a, t dbSNP:36093277
1655 1655 c, t dbSNP:10988483

Target ORF information:

RefSeq Version XM_011518772
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens paired related homeobox 2 (PRRX2), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011518772

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGCTTGGAG GTGAGTGTCC CAGCCCGGGG CGCGGTAGCG CCGCCAAGCG GAAGAAGAAG 
CAGCGGCGGA ACCGCACCAC GTTCAACAGC AGCCAACTGC AGGCGCTGGA GCGCGTGTTC
GAGCGCACGC ACTACCCCGA CGCCTTTGTG CGCGAGGAGC TTGCCCGGCG CGTCAACCTC
AGCGAGGCGC GCGTTCAGGT CTGGTTTCAG AACCGCCGCG CCAAGTTCCG CAGGAATGAA
AGGGCCATGC TGGCCAGCCG CTCTGCCTCG CTGCTCAAGT CCTACAGCCA GGAGGCCGCC
ATCGAGCAGC CCGTGGCTCC CCGGCCCACC GCCCTGAGTC CAGATTATCT CTCCTGGACA
GCCTCGTCCC CCTACAGCAC AGTGCCACCC TACAGCCCTG GGAGCTCAGG CCCCGCAACC
CCAGGGGTCA ACATGGCCAA CAGCATCGCC AGCCTCCGTC TCAAGGCCAA GGAGTTCAGC
CTGCACCACA GCCAGGTGCC TACGGTGAAC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu30413
Accession Version NM_016307.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 762bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear Document: OHu30413D_COA.pdf (pdf)
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product paired mesoderm homeobox protein 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC014645.1. On Nov 25, 2003 this sequence version replaced gi:12707581. Summary: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq, Jul 2008]. ##Evidence-Data-START## Transcript exon combination :: BC014645.1, AF061970.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGACAGCG CGGCCGCCGC CTTCGCCCTG GACAAGCCGG CGCTGGGCCC GGGGCCGCCG 
CCGCCTCCAC CCGCGCTGGG GCCCGGCGAC TGCGCCCAGG CGCGCAAGAA CTTCTCGGTG
AGCCACCTCC TGGACCTGGA AGAGGTGGCG GCGGCCGGGC GGCTGGCGGC GCGCCCCGGG
GCCAGGGCCG AGGCGCGGGA GGGCGCAGCA CGGGAGCCGT CCGGGGGCAG CAGCGGCAGC
GAGGCGGCGC CGCAGGATGG TGAGTGTCCC AGCCCGGGGC GCGGTAGCGC CGCCAAGCGG
AAGAAGAAGC AGCGGCGGAA CCGCACCACG TTCAACAGCA GCCAACTGCA GGCGCTGGAG
CGCGTGTTCG AGCGCACGCA CTACCCCGAC GCCTTTGTGC GCGAGGAGCT TGCCCGGCGC
GTCAACCTCA GCGAGGCGCG CGTTCAGGTC TGGTTTCAGA ACCGCCGCGC CAAGTTCCGC
AGGAATGAAA GGGCCATGCT GGCCAGCCGC TCTGCCTCGC TGCTCAAGTC CTACAGCCAG
GAGGCCGCCA TCGAGCAGCC CGTGGCTCCC CGGCCCACCG CCCTGAGTCC AGATTATCTC
TCCTGGACAG CCTCGTCCCC CTACAGCACA GTGCCACCCT ACAGCCCTGG GAGCTCAGGC
CCCGCAACCC CAGGGGTCAA CATGGCCAAC AGCATCGCCA GCCTCCGTCT CAAGGCCAAG
GAGTTCAGCC TGCACCACAG CCAGGTGCCT ACGGTGAACT GA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_057391.1
CDS228..989
Misc Feature(1)552..716(+)
Misc Feature(2)552..710(+)
Misc Feature(3)555..698(+)
Misc Feature(4)900..962(+)
Misc Feature(5)915..956(+)
Exon (1)1..486
Gene:PRRX2
Gene Synonym:
Exon (2)487..674
Gene:PRRX2
Gene Synonym:
Exon (3)675..853
Gene:PRRX2
Gene Synonym:
Exon (4)854..1311
Gene:PRRX2
Gene Synonym:
Translation
Position Chain Variation Link
25 25 c, g dbSNP:368393993
64 64 g, t dbSNP:575423504
77 77 a, c dbSNP:115147301
98 98 a, g dbSNP:539715466
120 120 a, t dbSNP:553713809
280 280 -, gcc dbSNP:761533769
299 299 a, c dbSNP:753269081
306 306 a, g dbSNP:758869156
325 325 a, g dbSNP:764488857
366 366 a, g dbSNP:751868612
490 490 a, c dbSNP:751921861
491 491 a, g dbSNP:564891395
499 499 g, t dbSNP:767772157
502 502 c, t dbSNP:777230786
503 503 g, t dbSNP:754567369
519 519 a, g, t dbSNP:527354835
520 520 c, t dbSNP:752216948
521 521 a, c, t dbSNP:370204978
524 524 a, g dbSNP:35865713
525 525 c, t dbSNP:746928887
526 526 g, t dbSNP:770826522
530 530 a, g dbSNP:201665194
534 534 a, c dbSNP:201179051
539 539 c, g dbSNP:149764500
543 543 c, t dbSNP:769856483
544 544 g, t dbSNP:775573934
548 548 c, t dbSNP:376858807
554 554 c, t dbSNP:768713520
556 556 c, t dbSNP:529534534
566 566 c, g dbSNP:774909161
567 567 a, g dbSNP:762197918
568 568 a, g dbSNP:370267786
572 572 a, g dbSNP:750705637
575 575 a, g dbSNP:759266648
584 584 a, g dbSNP:764916399
586 586 a, g dbSNP:537937463
589 589 -, c dbSNP:781559184
589 589 c, g, t dbSNP:373913153
590 590 c, t dbSNP:758038591
597 597 a, g dbSNP:777417092
599 599 a, g dbSNP:751553829
600 600 c, t dbSNP:546912518
603 603 a, g dbSNP:781060799
604 604 c, t dbSNP:745608136
617 617 a, c, g dbSNP:756329628
629 629 c, t dbSNP:749511698
632 632 a, g dbSNP:199887986
638 638 g, t dbSNP:774394592
640 640 c, t dbSNP:569564205
642 642 c, t dbSNP:748715547
644 644 a, g dbSNP:772420049
645 645 a, c dbSNP:773632263
647 647 a, c dbSNP:537836904
648 648 a, g dbSNP:766838695
651 651 a, g dbSNP:775348667
653 653 c, t dbSNP:376061825
660 660 c, g dbSNP:202114136
667 667 c, g dbSNP:763744669
691 691 a, g dbSNP:747544751
695 695 a, c, t dbSNP:538411699
697 697 -, c dbSNP:755828117
698 698 a, c dbSNP:777113929
700 700 a, g dbSNP:762716963
704 704 c, t dbSNP:763795890
705 705 c, t dbSNP:773912196
716 716 a, g dbSNP:761167838
718 718 a, g dbSNP:767037621
720 720 g, t dbSNP:545291388
722 722 c, t dbSNP:556265818
724 724 c, t dbSNP:760586243
736 736 a, g, t dbSNP:766187907
737 737 c, t dbSNP:755197464
741 741 c, g dbSNP:145779250
742 742 c, g dbSNP:140591214
745 745 c, t dbSNP:144448846
746 746 a, g dbSNP:146603979
755 755 a, g dbSNP:547352299
757 757 c, t dbSNP:777876138
760 760 a, g dbSNP:567572265
765 765 c, g dbSNP:771515908
770 770 g, t dbSNP:781713116
773 773 c, t dbSNP:746163957
777 777 a, g dbSNP:765923715
779 779 c, t dbSNP:768366620
780 780 a, g dbSNP:773930013
790 790 a, t dbSNP:761498521
791 791 a, g dbSNP:771533497
792 792 g, t dbSNP:772733281
793 793 c, t dbSNP:141327412
794 794 c, t dbSNP:766238887
798 798 c, g dbSNP:753647365
803 803 c, t dbSNP:759386453
806 806 c, g dbSNP:765077601
810 810 c, g dbSNP:143393943
812 812 a, g dbSNP:758622935
814 814 a, g dbSNP:201217720
816 816 c, g, t dbSNP:751649295
817 817 c, t dbSNP:781739454
823 823 a, c dbSNP:148368723
826 826 a, t dbSNP:569824624
827 827 a, c, t dbSNP:372702758
829 829 c, g dbSNP:140111310
841 841 c, t dbSNP:771719938
842 842 a, g dbSNP:553709679
846 846 a, c, g, t dbSNP:552481765
848 848 c, t dbSNP:759487699
861 861 c, g dbSNP:763963937
868 868 a, t dbSNP:530773145
871 871 c, g dbSNP:762092376
883 883 c, t dbSNP:150293718
888 888 c, t dbSNP:750493450
890 890 c, t dbSNP:544099756
891 891 a, g, t dbSNP:566612578
903 903 a, g dbSNP:755437873
907 907 a, g dbSNP:779219560
915 915 a, g dbSNP:746715077
917 917 c, t dbSNP:756852568
923 923 c, t dbSNP:138042846
924 924 a, g dbSNP:745318451
930 930 c, g dbSNP:769631139
933 933 c, t dbSNP:202233874
934 934 a, g dbSNP:201083423
938 938 c, g dbSNP:768608876
944 944 c, t dbSNP:200632042
945 945 -, a dbSNP:779650417
946 946 a, g dbSNP:762161505
950 950 a, g dbSNP:772358017
955 955 c, g dbSNP:773183325
979 979 c, t dbSNP:143523637
980 980 a, c, g dbSNP:373951160
986 986 c, t dbSNP:760016044
991 991 -, gtccagt dbSNP:748845072
991 991 a, g dbSNP:765610431
1001 1001 a, c dbSNP:28428946
1005 1005 a, g dbSNP:756907451
1010 1010 c, g dbSNP:780765136
1014 1014 c, t dbSNP:370487741
1015 1015 a, g dbSNP:549073959
1016 1016 c, t dbSNP:779397611
1035 1035 a, g dbSNP:116237845
1052 1052 c, t dbSNP:575443811
1065 1065 a, g dbSNP:373341887
1090 1090 a, g dbSNP:142417382
1115 1115 a, g dbSNP:756253077
1123 1123 a, c, g dbSNP:2241898
1134 1134 a, g dbSNP:780394237
1140 1140 c, t dbSNP:1051445
1147 1147 a, g dbSNP:370014709
1151 1151 c, g dbSNP:28441121
1195 1195 c, t dbSNP:535567000
1205 1205 c, t dbSNP:555876693
1256 1256 g, t dbSNP:73627671
1293 1293 -, t dbSNP:552520403
1300 1300 -, a, t dbSNP:36093277
1307 1307 c, t dbSNP:10988483

Target ORF information:

RefSeq Version NM_016307
Organism Homo sapiens (human)
Definition Homo sapiens paired related homeobox 2 (PRRX2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_016307

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGACAGCG CGGCCGCCGC CTTCGCCCTG GACAAGCCGG CGCTGGGCCC GGGGCCGCCG 
CCGCCTCCAC CCGCGCTGGG GCCCGGCGAC TGCGCCCAGG CGCGCAAGAA CTTCTCGGTG
AGCCACCTCC TGGACCTGGA AGAGGTGGCG GCGGCCGGGC GGCTGGCGGC GCGCCCCGGG
GCCAGGGCCG AGGCGCGGGA GGGCGCAGCA CGGGAGCCGT CCGGGGGCAG CAGCGGCAGC
GAGGCGGCGC CGCAGGATGG TGAGTGTCCC AGCCCGGGGC GCGGTAGCGC CGCCAAGCGG
AAGAAGAAGC AGCGGCGGAA CCGCACCACG TTCAACAGCA GCCAACTGCA GGCGCTGGAG
CGCGTGTTCG AGCGCACGCA CTACCCCGAC GCCTTTGTGC GCGAGGAGCT TGCCCGGCGC
GTCAACCTCA GCGAGGCGCG CGTTCAGGTC TGGTTTCAGA ACCGCCGCGC CAAGTTCCGC
AGGAATGAAA GGGCCATGCT GGCCAGCCGC TCTGCCTCGC TGCTCAAGTC CTACAGCCAG
GAGGCCGCCA TCGAGCAGCC CGTGGCTCCC CGGCCCACCG CCCTGAGTCC AGATTATCTC
TCCTGGACAG CCTCGTCCCC CTACAGCACA GTGCCACCCT ACAGCCCTGG GAGCTCAGGC
CCCGCAACCC CAGGGGTCAA CATGGCCAAC AGCATCGCCA GCCTCCGTCT CAAGGCCAAG
GAGTTCAGCC TGCACCACAG CCAGGTGCCT ACGGTGAACT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.