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PRRX2 cDNA ORF clone, Homo sapiens (human)

Gene Symbol PRRX2
Entrez Gene ID 51450
Full Name paired related homeobox 2
Synonyms PMX2, PRX2
General protein information
Preferred Names
paired mesoderm homeobox protein 2
Names
paired mesoderm homeobox protein 2
PRX-2
paired-related homeobox protein 2
paired-like homeodomain protein PRX2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9q34.1

Summary The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

604675


mRNA and Protein(s)

mRNA Protein Name
XM_011518771 XP_011517073 paired mesoderm homeobox protein 2 isoform X1
XM_011518772 XP_011517074 paired mesoderm homeobox protein 2 isoform X2
NM_016307 NP_057391 paired mesoderm homeobox protein 2


Homo sapiens (human) PRRX2 NP_057391.1
Pan troglodytes (chimpanzee) PRRX2 XP_520310.2
Macaca mulatta (Rhesus monkey) PRRX2 XP_001107634.1
Canis lupus familiaris (dog) PRRX2 XP_548419.3
Bos taurus (cattle) PRRX2 XP_002691720.3
Mus musculus (house mouse) Prrx2 NP_033142.2
Rattus norvegicus (Norway rat) Prrx2 NP_001099209.1
Gallus gallus (chicken) PRRX2 XP_415476.3
Xenopus (Silurana) tropicalis (western clawed frog) prrx2 XP_002940803.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PRRX2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PRRX2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu67943 XM_011518771 PREDICTED: Homo sapiens paired related homeobox 2 (PRRX2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu67944 XM_011518772 PREDICTED: Homo sapiens paired related homeobox 2 (PRRX2), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu30413
NM_016307 Homo sapiens paired related homeobox 2 (PRRX2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99.50-$139.30
$199.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu67943
Clone ID Related Accession (Same CDS sequence) XM_011518771
Accession Version XM_011518771.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 528bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product paired mesoderm homeobox protein 2 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008470.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
ATGCATTCCA AGGAGACAGA AAACAGTGAG TGTCCCAGCC CGGGGCGCGG TAGCGCCGCC 
AAGCGGAAGA AGAAGCAGCG GCGGAACCGC ACCACGTTCA ACAGCAGCCA ACTGCAGGCG
CTGGAGCGCG TGTTCGAGCG CACGCACTAC CCCGACGCCT TTGTGCGCGA GGAGCTTGCC
CGGCGCGTCA ACCTCAGCGA GGCGCGCGTT CAGGTCTGGT TTCAGAACCG CCGCGCCAAG
TTCCGCAGGA ATGAAAGGGC CATGCTGGCC AGCCGCTCTG CCTCGCTGCT CAAGTCCTAC
AGCCAGGAGG CCGCCATCGA GCAGCCCGTG GCTCCCCGGC CCACCGCCCT GAGTCCAGAT
TATCTCTCCT GGACAGCCTC GTCCCCCTAC AGCACAGTGC CACCCTACAG CCCTGGGAGC
TCAGGCCCCG CAACCCCAGG GGTCAACATG GCCAACAGCA TCGCCAGCCT CCGTCTCAAG
GCCAAGGAGT TCAGCCTGCA CCACAGCCAG GTGCCTACGG TGAACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011517073.1
CDS16..543
Misc Feature(1)106..270(+)
Misc Feature(2)106..264(+)
Misc Feature(3)109..252(+)
Misc Feature(4)454..516(+)
Translation

Target ORF information:

RefSeq Version XM_011518771
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens paired related homeobox 2 (PRRX2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011518771

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGCATTCCA AGGAGACAGA AAACAGTGAG TGTCCCAGCC CGGGGCGCGG TAGCGCCGCC 
AAGCGGAAGA AGAAGCAGCG GCGGAACCGC ACCACGTTCA ACAGCAGCCA ACTGCAGGCG
CTGGAGCGCG TGTTCGAGCG CACGCACTAC CCCGACGCCT TTGTGCGCGA GGAGCTTGCC
CGGCGCGTCA ACCTCAGCGA GGCGCGCGTT CAGGTCTGGT TTCAGAACCG CCGCGCCAAG
TTCCGCAGGA ATGAAAGGGC CATGCTGGCC AGCCGCTCTG CCTCGCTGCT CAAGTCCTAC
AGCCAGGAGG CCGCCATCGA GCAGCCCGTG GCTCCCCGGC CCACCGCCCT GAGTCCAGAT
TATCTCTCCT GGACAGCCTC GTCCCCCTAC AGCACAGTGC CACCCTACAG CCCTGGGAGC
TCAGGCCCCG CAACCCCAGG GGTCAACATG GCCAACAGCA TCGCCAGCCT CCGTCTCAAG
GCCAAGGAGT TCAGCCTGCA CCACAGCCAG GTGCCTACGG TGAACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu67944
Clone ID Related Accession (Same CDS sequence) XM_011518772
Accession Version XM_011518772.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product paired mesoderm homeobox protein 2 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008470.20) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
ATGCTTGGAG GTGAGTGTCC CAGCCCGGGG CGCGGTAGCG CCGCCAAGCG GAAGAAGAAG 
CAGCGGCGGA ACCGCACCAC GTTCAACAGC AGCCAACTGC AGGCGCTGGA GCGCGTGTTC
GAGCGCACGC ACTACCCCGA CGCCTTTGTG CGCGAGGAGC TTGCCCGGCG CGTCAACCTC
AGCGAGGCGC GCGTTCAGGT CTGGTTTCAG AACCGCCGCG CCAAGTTCCG CAGGAATGAA
AGGGCCATGC TGGCCAGCCG CTCTGCCTCG CTGCTCAAGT CCTACAGCCA GGAGGCCGCC
ATCGAGCAGC CCGTGGCTCC CCGGCCCACC GCCCTGAGTC CAGATTATCT CTCCTGGACA
GCCTCGTCCC CCTACAGCAC AGTGCCACCC TACAGCCCTG GGAGCTCAGG CCCCGCAACC
CCAGGGGTCA ACATGGCCAA CAGCATCGCC AGCCTCCGTC TCAAGGCCAA GGAGTTCAGC
CTGCACCACA GCCAGGTGCC TACGGTGAAC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011517074.1
CDS825..1337
Misc Feature(1)900..1064(+)
Misc Feature(2)900..1058(+)
Misc Feature(3)903..1046(+)
Misc Feature(4)1248..1310(+)
Translation

Target ORF information:

RefSeq Version XM_011518772
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens paired related homeobox 2 (PRRX2), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011518772

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGCTTGGAG GTGAGTGTCC CAGCCCGGGG CGCGGTAGCG CCGCCAAGCG GAAGAAGAAG 
CAGCGGCGGA ACCGCACCAC GTTCAACAGC AGCCAACTGC AGGCGCTGGA GCGCGTGTTC
GAGCGCACGC ACTACCCCGA CGCCTTTGTG CGCGAGGAGC TTGCCCGGCG CGTCAACCTC
AGCGAGGCGC GCGTTCAGGT CTGGTTTCAG AACCGCCGCG CCAAGTTCCG CAGGAATGAA
AGGGCCATGC TGGCCAGCCG CTCTGCCTCG CTGCTCAAGT CCTACAGCCA GGAGGCCGCC
ATCGAGCAGC CCGTGGCTCC CCGGCCCACC GCCCTGAGTC CAGATTATCT CTCCTGGACA
GCCTCGTCCC CCTACAGCAC AGTGCCACCC TACAGCCCTG GGAGCTCAGG CCCCGCAACC
CCAGGGGTCA ACATGGCCAA CAGCATCGCC AGCCTCCGTC TCAAGGCCAA GGAGTTCAGC
CTGCACCACA GCCAGGTGCC TACGGTGAAC TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu30413
Clone ID Related Accession (Same CDS sequence) NM_016307
Accession Version NM_016307.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 762bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product paired mesoderm homeobox protein 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC014645.1. On Nov 25, 2003 this sequence version replaced gi:12707581. ##Evidence-Data-START## Transcript exon combination :: BC014645.1, AF061970.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGACAGCG CGGCCGCCGC CTTCGCCCTG GACAAGCCGG CGCTGGGCCC GGGGCCGCCG 
CCGCCTCCAC CCGCGCTGGG GCCCGGCGAC TGCGCCCAGG CGCGCAAGAA CTTCTCGGTG
AGCCACCTCC TGGACCTGGA AGAGGTGGCG GCGGCCGGGC GGCTGGCGGC GCGCCCCGGG
GCCAGGGCCG AGGCGCGGGA GGGCGCAGCA CGGGAGCCGT CCGGGGGCAG CAGCGGCAGC
GAGGCGGCGC CGCAGGATGG TGAGTGTCCC AGCCCGGGGC GCGGTAGCGC CGCCAAGCGG
AAGAAGAAGC AGCGGCGGAA CCGCACCACG TTCAACAGCA GCCAACTGCA GGCGCTGGAG
CGCGTGTTCG AGCGCACGCA CTACCCCGAC GCCTTTGTGC GCGAGGAGCT TGCCCGGCGC
GTCAACCTCA GCGAGGCGCG CGTTCAGGTC TGGTTTCAGA ACCGCCGCGC CAAGTTCCGC
AGGAATGAAA GGGCCATGCT GGCCAGCCGC TCTGCCTCGC TGCTCAAGTC CTACAGCCAG
GAGGCCGCCA TCGAGCAGCC CGTGGCTCCC CGGCCCACCG CCCTGAGTCC AGATTATCTC
TCCTGGACAG CCTCGTCCCC CTACAGCACA GTGCCACCCT ACAGCCCTGG GAGCTCAGGC
CCCGCAACCC CAGGGGTCAA CATGGCCAAC AGCATCGCCA GCCTCCGTCT CAAGGCCAAG
GAGTTCAGCC TGCACCACAG CCAGGTGCCT ACGGTGAACT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_057391.1
CDS228..989
Misc Feature(1)552..716(+)
Misc Feature(2)552..710(+)
Misc Feature(3)555..698(+)
Misc Feature(4)900..962(+)
Misc Feature(5)915..956(+)
Exon (1)1..486
Gene:PRRX2
Gene Synonym:
Exon (2)487..674
Gene:PRRX2
Gene Synonym:
Exon (3)675..853
Gene:PRRX2
Gene Synonym:
Exon (4)854..1311
Gene:PRRX2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_016307
Organism Homo sapiens (human)
Definition Homo sapiens paired related homeobox 2 (PRRX2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_016307

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGACAGCG CGGCCGCCGC CTTCGCCCTG GACAAGCCGG CGCTGGGCCC GGGGCCGCCG 
CCGCCTCCAC CCGCGCTGGG GCCCGGCGAC TGCGCCCAGG CGCGCAAGAA CTTCTCGGTG
AGCCACCTCC TGGACCTGGA AGAGGTGGCG GCGGCCGGGC GGCTGGCGGC GCGCCCCGGG
GCCAGGGCCG AGGCGCGGGA GGGCGCAGCA CGGGAGCCGT CCGGGGGCAG CAGCGGCAGC
GAGGCGGCGC CGCAGGATGG TGAGTGTCCC AGCCCGGGGC GCGGTAGCGC CGCCAAGCGG
AAGAAGAAGC AGCGGCGGAA CCGCACCACG TTCAACAGCA GCCAACTGCA GGCGCTGGAG
CGCGTGTTCG AGCGCACGCA CTACCCCGAC GCCTTTGTGC GCGAGGAGCT TGCCCGGCGC
GTCAACCTCA GCGAGGCGCG CGTTCAGGTC TGGTTTCAGA ACCGCCGCGC CAAGTTCCGC
AGGAATGAAA GGGCCATGCT GGCCAGCCGC TCTGCCTCGC TGCTCAAGTC CTACAGCCAG
GAGGCCGCCA TCGAGCAGCC CGTGGCTCCC CGGCCCACCG CCCTGAGTCC AGATTATCTC
TCCTGGACAG CCTCGTCCCC CTACAGCACA GTGCCACCCT ACAGCCCTGG GAGCTCAGGC
CCCGCAACCC CAGGGGTCAA CATGGCCAAC AGCATCGCCA GCCTCCGTCT CAAGGCCAAG
GAGTTCAGCC TGCACCACAG CCAGGTGCCT ACGGTGAACT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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