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ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 [Homo sapiens (human)]

Gene Symbol ATP5F1
Entrez Gene ID 515
Full Name ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
Synonyms PIG47
General protein information
Preferred Names
ATP synthase subunit b, mitochondrial
Names
ATP synthase subunit b, mitochondrial
ATPase subunit b
H+-ATP synthase subunit b
ATP synthase B chain, mitochondrial
cell proliferation-inducing protein 47
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1
NP_001679.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p13.2

Summary This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the b subunit of the proton channel. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

603270

Disorder Html:





The following ATP5F1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ATP5F1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu21926 NM_001688 Homo sapiens ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 (ATP5F1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu21926
Accession Version NM_001688.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 771bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product ATP synthase F(0) complex subunit B1, mitochondrial precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BF237506.1, AL390195.10, AW778751.1 and AI754631.1. On Jan 27, 2006 this sequence version replaced gi:50593508. Summary: This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the b subunit of the proton channel. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: AK291077.1, BC016350.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGCTGTCCC GGGTGGTACT TTCCGCCGCC GCCACAGCGG CCCCCTCTCT GAAGAATGCA 
GCCTTCCTAG GTCCAGGGGT ATTGCAGGCA ACAAGGACCT TTCATACAGG GCAGCCACAC
CTTGTCCCTG TACCACCTCT TCCTGAATAC GGAGGAAAAG TTCGTTATGG ACTGATCCCT
GAGGAATTCT TCCAGTTTCT TTATCCTAAA ACTGGTGTAA CAGGACCCTA TGTACTCGGA
ACTGGGCTTA TCTTGTACGC TTTATCCAAA GAAATATATG TGATTAGCGC AGAGACCTTC
ACTGCCCTAT CAGTACTAGG TGTAATGGTC TATGGAATTA AAAAATATGG TCCCTTTGTT
GCAGACTTTG CTGATAAACT CAATGAGCAA AAACTTGCCC AACTAGAAGA GGCGAAGCAG
GCTTCCATCC AACACATCCA GAATGCAATT GATACGGAGA AGTCACAACA GGCACTGGTT
CAGAAGCGCC ATTACCTTTT TGATGTGCAA AGGAATAACA TTGCTATGGC TTTGGAAGTT
ACTTACCGGG AACGACTGTA TAGAGTATAT AAGGAAGTAA AGAATCGCCT GGACTATCAT
ATATCTGTGC AGAACATGAT GCGTCGAAAG GAACAAGAAC ACATGATAAA TTGGGTGGAG
AAGCACGTGG TGCAAAGCAT CTCCACACAG CAGGAAAAGG AGACAATTGC CAAGTGCATT
GCGGACCTAA AGCTGCTGGC AAAGAAGGCT CAAGCACAGC CAGTTATGTA A
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001679.2
CDS422..1192
Misc Feature(1)23..25(+)
Misc Feature(2)668..1153(+)
Misc Feature(3)1082..1084(+)
Misc Feature(4)1118..1120(+)
Exon (1)1..461
Gene:ATP5F1
Gene Synonym:
Exon (2)462..498
Gene:ATP5F1
Gene Synonym:
Exon (3)499..644
Gene:ATP5F1
Gene Synonym:
Exon (4)645..808
Gene:ATP5F1
Gene Synonym:
Exon (5)809..934
Gene:ATP5F1
Gene Synonym:
Exon (6)935..1114
Gene:ATP5F1
Gene Synonym:
Exon (7)1115..2116
Gene:ATP5F1
Gene Synonym:
Translation
Position Chain Variation Link
7 7 a, g dbSNP:201286094
8 8 a, g dbSNP:755337873
12 12 a, g dbSNP:765480397
15 15 a, g dbSNP:753270642
17 17 a, g dbSNP:758776607
18 18 a, g dbSNP:778007058
24 24 -, g dbSNP:769189971
24 24 -, a dbSNP:761146269
25 25 a, g dbSNP:751688255
25 25 -, g dbSNP:776941477
26 26 a, c, g, t dbSNP:11548427
27 27 a, c, g, t dbSNP:75410241
28 28 c, g, t dbSNP:768471611
29 29 c, g dbSNP:761289527
37 37 a, t dbSNP:576209444
44 44 c, t dbSNP:771751745
59 59 -, tccaac dbSNP:762262343
62 62 a, g dbSNP:772883012
70 70 -, ggtt dbSNP:765889862
71 71 c, t dbSNP:542531420
87 87 a, c, g, t dbSNP:760197399
91 91 a, g dbSNP:763586389
94 94 c, t dbSNP:562212182
95 95 a, g dbSNP:751741504
101 101 c, t dbSNP:757385818
103 103 a, c, t dbSNP:1270853
104 104 a, g dbSNP:756220773
109 109 a, g dbSNP:779964177
118 118 c, t dbSNP:749021299
119 119 a, c dbSNP:768627924
129 129 a, g dbSNP:778789770
134 134 c, t dbSNP:748037698
137 137 a, g dbSNP:144089879
142 142 a, t dbSNP:772651959
147 147 a, c dbSNP:760380524
154 154 c, t dbSNP:770487019
163 163 a, c dbSNP:775983291
177 177 a, c dbSNP:763208191
192 192 c, t dbSNP:564105379
196 196 a, t dbSNP:752147544
197 197 a, g dbSNP:533100301
206 206 a, c dbSNP:767707395
207 207 c, t dbSNP:750463644
224 224 a, c dbSNP:756414576
232 232 a, g dbSNP:2298186
239 239 g, t dbSNP:766487176
243 243 a, g dbSNP:753706233
244 244 a, g dbSNP:754797792
245 245 c, g dbSNP:778630320
255 255 c, g dbSNP:748092662
258 258 g, t dbSNP:758266820
262 262 c, t dbSNP:549886016
266 266 a, g dbSNP:746490766
269 269 a, c dbSNP:770669361
270 270 -, t dbSNP:751230630
276 276 -, a dbSNP:759181162
276 276 a, t dbSNP:776120563
277 277 -, a dbSNP:767126922
277 277 a, t dbSNP:2298187
278 278 -, a dbSNP:752306973
278 278 a, t dbSNP:745482439
284 284 c, t dbSNP:769152539
293 293 a, t dbSNP:774786021
294 294 a, g dbSNP:762474319
297 297 c, t dbSNP:763301407
298 298 c, t dbSNP:768122869
301 301 a, c dbSNP:773388788
303 303 a, c, g dbSNP:760638955
304 304 a, t dbSNP:754029560
306 306 c, g dbSNP:761487393
309 309 g, t dbSNP:535613026
311 311 a, c dbSNP:549274125
313 313 a, c dbSNP:758390032
314 314 a, c dbSNP:777552361
316 316 -, t dbSNP:756092980
320 320 c, t dbSNP:746571813
323 323 c, g dbSNP:756751943
325 325 c, t dbSNP:780709227
328 328 c, g dbSNP:745515487
335 335 a, g dbSNP:769562154
340 340 a, c dbSNP:774910821
341 341 a, g dbSNP:748498765
347 347 c, g, t dbSNP:565793834
350 350 g, t dbSNP:374809270
353 353 c, t dbSNP:11553278
353 353 c, t dbSNP:1264899
355 355 a, c, t dbSNP:776626095
355 355 -, t dbSNP:777872357
356 356 g, t dbSNP:553921206
360 360 c, t dbSNP:576814686
367 367 g, t dbSNP:763288150
368 368 a, t dbSNP:762707644
369 369 c, g dbSNP:763912567
370 370 a, t dbSNP:751478587
371 371 c, t dbSNP:757147686
372 372 c, t dbSNP:780629447
377 377 c, g dbSNP:749937380
379 379 a, g dbSNP:372461676
382 382 c, g dbSNP:779820639
384 384 c, g, t dbSNP:376540396
386 386 a, g dbSNP:370991921
387 387 a, g dbSNP:747475994
389 389 a, t dbSNP:112858760
391 391 a, g dbSNP:776750889
392 392 c, t dbSNP:759592698
399 399 c, t dbSNP:377259164
401 401 c, g dbSNP:3209756
410 410 c, g dbSNP:763190213
413 413 g, t dbSNP:200429045
414 414 c, g, t dbSNP:562409675
415 415 c, g dbSNP:767460908
421 421 c, t dbSNP:750004922
429 429 c, g, t dbSNP:755709315
430 430 c, t dbSNP:753545373
431 431 a, c dbSNP:754600948
434 434 c, g dbSNP:778056395
436 436 a, g dbSNP:374607908
437 437 a, g dbSNP:368018920
451 451 c, g dbSNP:11553284
453 453 c, t dbSNP:781646701
455 455 a, t dbSNP:11553281
456 456 -, c dbSNP:757076011
457 457 a, g dbSNP:746322583
462 462 a, c dbSNP:773084651
463 463 c, t dbSNP:760752798
468 468 c, t dbSNP:569768542
471 471 c, t dbSNP:776043138
476 476 a, c dbSNP:756442495
483 483 c, g, t dbSNP:778130788
488 488 c, t dbSNP:143447407
492 492 c, g dbSNP:757976399
494 494 c, t dbSNP:767877355
500 500 g, t dbSNP:770878179
520 520 c, t dbSNP:539774261
525 525 a, g dbSNP:150771597
529 529 a, g dbSNP:769600505
532 532 c, g dbSNP:775109914
533 533 c, g dbSNP:762432243
538 538 a, g dbSNP:11553283
550 550 g, t dbSNP:768108339
552 552 c, t dbSNP:774026445
554 554 c, t dbSNP:761389778
555 555 a, c dbSNP:374654547
557 557 c, t dbSNP:754140123
564 564 c, g dbSNP:760155692
570 570 a, g dbSNP:143525671
571 571 c, t dbSNP:752873057
572 572 a, g dbSNP:140312350
578 578 a, g dbSNP:575607915
584 584 c, t dbSNP:751833359
585 585 a, g dbSNP:757360032
588 588 a, g dbSNP:145422069
589 589 c, t dbSNP:781095726
593 593 c, t dbSNP:745642833
600 600 c, t dbSNP:756726209
607 607 a, g dbSNP:779993797
633 633 c, t dbSNP:369841642
640 640 a, g dbSNP:749185529
650 650 c, t dbSNP:755894961
653 653 a, g dbSNP:61752545
655 655 a, g dbSNP:749238528
658 658 c, t dbSNP:61752543
661 661 a, g dbSNP:778462420
671 671 a, g dbSNP:151112830
675 675 c, t dbSNP:771805671
679 679 c, t dbSNP:772760964
680 680 a, g dbSNP:138675238
688 688 c, g dbSNP:770057473
689 689 a, g dbSNP:775935392
693 693 a, g dbSNP:17850025
703 703 g, t dbSNP:41314011
709 709 c, t dbSNP:148039333
710 710 a, g dbSNP:774610006
712 712 a, c, g dbSNP:376770527
713 713 c, g dbSNP:370896481
715 715 g, t dbSNP:767597893
722 722 a, g dbSNP:750616843
725 725 a, g dbSNP:11553282
733 733 a, g dbSNP:766220727
743 743 a, g dbSNP:753627949
751 751 c, g dbSNP:754949769
753 753 a, t dbSNP:759699044
772 772 c, t dbSNP:17849983
777 777 c, t dbSNP:778799728
782 782 a, g dbSNP:371319407
784 784 a, c dbSNP:752631080
786 786 a, c dbSNP:572819940
787 787 c, t dbSNP:777269751
819 819 a, c dbSNP:773207757
821 821 a, c dbSNP:11553279
825 825 c, t dbSNP:760721320
827 827 a, g dbSNP:770948319
834 834 c, t dbSNP:11553277
835 835 a, g dbSNP:759686657
840 840 a, g dbSNP:147175114
841 841 a, g dbSNP:564164027
845 845 g, t dbSNP:752520640
856 856 a, c dbSNP:762862337
866 866 a, g dbSNP:764057361
869 869 a, g, t dbSNP:150276317
872 872 c, g dbSNP:767073765
876 876 c, t dbSNP:1264895
877 877 a, g dbSNP:755817721
878 878 c, g dbSNP:779213739
880 880 a, g dbSNP:201572368
888 888 a, g dbSNP:748517197
897 897 g, t dbSNP:570082983
898 898 a, g dbSNP:778367498
902 902 a, c dbSNP:185647013
908 908 c, t dbSNP:747473562
912 912 a, g dbSNP:771003345
917 917 c, g dbSNP:765923102
935 935 a, g dbSNP:758823326
941 941 a, g dbSNP:777931213
950 950 a, g dbSNP:144377157
956 956 a, g dbSNP:368586672
962 962 a, g dbSNP:781312478
968 968 c, t dbSNP:371788562
969 969 a, g dbSNP:201778705
971 971 c, g dbSNP:775801229
973 973 a, g dbSNP:749406776
974 974 c, t dbSNP:760514793
975 975 a, g dbSNP:375518422
978 978 a, t dbSNP:774278975
984 984 c, g dbSNP:537603530
988 988 a, g dbSNP:761912371
994 994 a, g dbSNP:767531827
996 996 a, g dbSNP:772898298
999 999 c, t dbSNP:534137182
1000 1000 a, g dbSNP:141292134
1002 1002 a, g dbSNP:17850024
1007 1007 c, t dbSNP:200467988
1008 1008 a, g, t dbSNP:574830737
1017 1017 a, g dbSNP:201457142
1022 1022 a, g dbSNP:202089486
1025 1025 a, t dbSNP:757798524
1026 1026 c, t dbSNP:781645142
1043 1043 c, g, t dbSNP:151251385
1044 1044 a, g dbSNP:779942500
1046 1046 c, t dbSNP:749584142
1047 1047 a, g dbSNP:768759849
1051 1051 -, g dbSNP:780075681
1055 1055 c, g dbSNP:778895390
1058 1058 a, c, g dbSNP:182170395
1062 1062 a, g dbSNP:773316141
1063 1063 c, t dbSNP:78375935
1064 1064 a, g dbSNP:770487268
1065 1065 c, t dbSNP:573246874
1066 1066 c, g dbSNP:759299462
1069 1069 a, g dbSNP:764834418
1088 1088 a, g dbSNP:146878380
1096 1096 a, g dbSNP:565196606
1110 1110 a, g dbSNP:374781296
1120 1120 a, g dbSNP:376802418
1123 1123 a, g dbSNP:776244761
1126 1126 a, g dbSNP:758943813
1136 1136 c, g, t dbSNP:769241043
1137 1137 a, g dbSNP:762522611
1139 1139 a, g dbSNP:767930458
1143 1143 c, t dbSNP:773447587
1144 1144 a, c, g dbSNP:761288089
1150 1150 a, g dbSNP:142204470
1153 1153 g, t dbSNP:755140912
1172 1172 c, g, t dbSNP:765343628
1183 1183 a, g dbSNP:369899764
1192 1192 a, g dbSNP:777688122
1195 1195 a, g dbSNP:746748500
1197 1197 a, g, t dbSNP:757264247
1200 1200 c, t dbSNP:200707226
1202 1202 c, t dbSNP:769294372
1203 1203 c, g dbSNP:774970442
1207 1207 a, g dbSNP:749010309
1208 1208 c, t dbSNP:768269878
1224 1224 -, a dbSNP:773510743
1238 1238 a, g dbSNP:558718946
1250 1250 g, t dbSNP:569210356
1299 1299 a, g dbSNP:150328066
1354 1354 c, t dbSNP:138013503
1388 1388 c, g dbSNP:573759476
1403 1403 c, t dbSNP:749607329
1404 1404 a, g dbSNP:17027704
1471 1471 a, t dbSNP:532160227
1485 1485 g, t dbSNP:778512199
1521 1521 a, g dbSNP:186937939
1532 1532 c, g dbSNP:191668877
1546 1546 c, t dbSNP:183887376
1575 1575 a, c dbSNP:17027711
1594 1594 c, g dbSNP:188939805
1614 1614 g, t dbSNP:112516088
1698 1698 c, g dbSNP:10489793
1707 1707 a, g dbSNP:779664099
1726 1726 a, g dbSNP:147218131
1733 1733 a, g dbSNP:547656425
1753 1753 c, t dbSNP:191481445
1755 1755 a, c dbSNP:533100920
1763 1763 a, t dbSNP:548125797
1769 1769 g, t dbSNP:550019219
1840 1840 a, g dbSNP:569172994
1883 1883 a, c dbSNP:768367938
1933 1933 a, g dbSNP:776273885
1955 1955 c, t dbSNP:538196416
1956 1956 a, g dbSNP:761399411
1961 1961 c, t dbSNP:772171719
1990 1990 g, t dbSNP:775504618
2018 2018 a, g dbSNP:567075519
2022 2022 a, g dbSNP:11587579
2024 2024 a, c dbSNP:776464982
2045 2045 a, g dbSNP:761663849
2063 2063 c, g dbSNP:377688327
2087 2087 c, t dbSNP:28645563
2098 2098 a, g dbSNP:542717367
2099 2099 -, a dbSNP:34311324
2102 2102 a, g dbSNP:12083696

Target ORF information:

RefSeq Version NM_001688
Organism Homo sapiens (human)
Definition Homo sapiens ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 (ATP5F1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001688

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGCTGTCCC GGGTGGTACT TTCCGCCGCC GCCACAGCGG CCCCCTCTCT GAAGAATGCA 
GCCTTCCTAG GTCCAGGGGT ATTGCAGGCA ACAAGGACCT TTCATACAGG GCAGCCACAC
CTTGTCCCTG TACCACCTCT TCCTGAATAC GGAGGAAAAG TTCGTTATGG ACTGATCCCT
GAGGAATTCT TCCAGTTTCT TTATCCTAAA ACTGGTGTAA CAGGACCCTA TGTACTCGGA
ACTGGGCTTA TCTTGTACGC TTTATCCAAA GAAATATATG TGATTAGCGC AGAGACCTTC
ACTGCCCTAT CAGTACTAGG TGTAATGGTC TATGGAATTA AAAAATATGG TCCCTTTGTT
GCAGACTTTG CTGATAAACT CAATGAGCAA AAACTTGCCC AACTAGAAGA GGCGAAGCAG
GCTTCCATCC AACACATCCA GAATGCAATT GATACGGAGA AGTCACAACA GGCACTGGTT
CAGAAGCGCC ATTACCTTTT TGATGTGCAA AGGAATAACA TTGCTATGGC TTTGGAAGTT
ACTTACCGGG AACGACTGTA TAGAGTATAT AAGGAAGTAA AGAATCGCCT GGACTATCAT
ATATCTGTGC AGAACATGAT GCGTCGAAAG GAACAAGAAC ACATGATAAA TTGGGTGGAG
AAGCACGTGG TGCAAAGCAT CTCCACACAG CAGGAAAAGG AGACAATTGC CAAGTGCATT
GCGGACCTAA AGCTGCTGGC AAAGAAGGCT CAAGCACAGC CAGTTATGTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.