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MYOZ2 cDNA ORF clone, Homo sapiens (human)

Gene Symbol MYOZ2
Entrez Gene ID 51778
Full Name myozenin 2
Synonyms C4orf5, CMH16, CS-1
General protein information
Preferred Names
myozenin-2
Names
myozenin-2
FATZ-related protein 2
muscle-specific protein
calcineurin-binding protein calsarcin-1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4q26-q27

Summary The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder. [provided by RefSeq, Aug 2011]. lac of sum
Disorder MIM:

605602


mRNA and Protein(s)

mRNA Protein Name
XM_006714234 XP_006714297 myozenin-2 isoform X1
NM_016599 NP_057683 myozenin-2


Homo sapiens (human) MYOZ2 NP_057683.1
Pan troglodytes (chimpanzee) MYOZ2 XP_001148878.1
Macaca mulatta (Rhesus monkey) MYOZ2 XP_001098621.1
Canis lupus familiaris (dog) MYOZ2 XP_535703.3
Bos taurus (cattle) MYOZ2 NP_001015676.1
Mus musculus (house mouse) Myoz2 NP_067478.1
Gallus gallus (chicken) MYOZ2 NP_001264756.1
Danio rerio (zebrafish) myoz2b NP_957148.2
Xenopus (Silurana) tropicalis (western clawed frog) myoz2 NP_001011415.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MYOZ2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MYOZ2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu38965 XM_006714234 PREDICTED: Homo sapiens myozenin 2 (MYOZ2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu21456
NM_016599 Homo sapiens myozenin 2 (MYOZ2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu38965
Clone ID Related Accession (Same CDS sequence) XM_006714234
Accession Version XM_006714234.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 588bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product myozenin-2 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_016354.20) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578809164. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
ATGCTATCAC ATAATACTAT GATGAAGCAG AGAAAACAGC AAGCAACAGC CATCATGAAG 
GAAGTCCATG GAAATGATGT TGATGGCATG GACCTGGGCA AAAAGGTCAG CATCCCCAGA
GACATCATGT TGGAAGAATT ATCCCATCTC AGTAACCGTG GTGCCAGGCT ATTTAAGATG
CGTCAAAGAA GATCTGACAA ATACACATTT GAAAATTTCC AGTATCAATC TAGAGCACAA
ATAAATCACA GTATTGCTAT GCAGAATGGG AAAGTGGATG GAAGTAACTT GGAAGGTGGT
TCGCAGCAAG CCCCCTTGAC TCCTCCCAAC ACCCCAGATC CACGAAGCCC TCCAAATCCA
GACAACATTG CTCCAGGATA TTCTGGACCA CTGAAGGAAA TTCCTCCTGA AAAATTCAAC
ACCACAGCTG TCCCTAAGTA CTATCAATCT CCCTGGGAAC AAGCCATTAG CAATGATCCG
GAGCTTTTAG AGGCTTTATA TCCTAAACTT TTCAAGCCTG AAGGAAAGGC AGAACTGCCT
GATTACAGGA GCTTTAACAG GGGTTCAAGA CTTCATTGGA GGAAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006714297.1
CDS182..769
Misc Feature(1)182..>742(+)
Translation

Target ORF information:

RefSeq Version XM_006714234
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens myozenin 2 (MYOZ2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006714234

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGCTATCAC ATAATACTAT GATGAAGCAG AGAAAACAGC AAGCAACAGC CATCATGAAG 
GAAGTCCATG GAAATGATGT TGATGGCATG GACCTGGGCA AAAAGGTCAG CATCCCCAGA
GACATCATGT TGGAAGAATT ATCCCATCTC AGTAACCGTG GTGCCAGGCT ATTTAAGATG
CGTCAAAGAA GATCTGACAA ATACACATTT GAAAATTTCC AGTATCAATC TAGAGCACAA
ATAAATCACA GTATTGCTAT GCAGAATGGG AAAGTGGATG GAAGTAACTT GGAAGGTGGT
TCGCAGCAAG CCCCCTTGAC TCCTCCCAAC ACCCCAGATC CACGAAGCCC TCCAAATCCA
GACAACATTG CTCCAGGATA TTCTGGACCA CTGAAGGAAA TTCCTCCTGA AAAATTCAAC
ACCACAGCTG TCCCTAAGTA CTATCAATCT CCCTGGGAAC AAGCCATTAG CAATGATCCG
GAGCTTTTAG AGGCTTTATA TCCTAAACTT TTCAAGCCTG AAGGAAAGGC AGAACTGCCT
GATTACAGGA GCTTTAACAG GGGTTCAAGA CTTCATTGGA GGAAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu21456
Clone ID Related Accession (Same CDS sequence) NM_016599
Accession Version NM_016599.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 795bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product myozenin-2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP370492.1, BC020932.1, AC092656.1 and BM091578.1. This sequence is a reference standard in the RefSeqGene project. On Aug 11, 2011 this sequence version replaced gi:187936928. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY013295.1, AJ252149.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2144120 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGCTATCAC ATAATACTAT GATGAAGCAG AGAAAACAGC AAGCAACAGC CATCATGAAG 
GAAGTCCATG GAAATGATGT TGATGGCATG GACCTGGGCA AAAAGGTCAG CATCCCCAGA
GACATCATGT TGGAAGAATT ATCCCATCTC AGTAACCGTG GTGCCAGGCT ATTTAAGATG
CGTCAAAGAA GATCTGACAA ATACACATTT GAAAATTTCC AGTATCAATC TAGAGCACAA
ATAAATCACA GTATTGCTAT GCAGAATGGG AAAGTGGATG GAAGTAACTT GGAAGGTGGT
TCGCAGCAAG CCCCCTTGAC TCCTCCCAAC ACCCCAGATC CACGAAGCCC TCCAAATCCA
GACAACATTG CTCCAGGATA TTCTGGACCA CTGAAGGAAA TTCCTCCTGA AAAATTCAAC
ACCACAGCTG TCCCTAAGTA CTATCAATCT CCCTGGGAAC AAGCCATTAG CAATGATCCG
GAGCTTTTAG AGGCTTTATA TCCTAAACTT TTCAAGCCTG AAGGAAAGGC AGAACTGCCT
GATTACAGGA GCTTTAACAG GGTTGCCACA CCATTTGGAG GTTTTGAAAA AGCATCAAGA
ATGGTTAAAT TTAAAGTTCC AGATTTTGAG CTACTATTGC TAACAGATCC CAGGTTTATG
TCCTTTGTCA ATCCCCTTTC TGGCAGACGG TCCTTTAATA GGACTCCTAA GGGATGGATA
TCTGAGAATA TTCCTATAGT GATAACAACC GAACCTACAG ATGATACCAC TGTACCAGAA
TCAGAAGACC TATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_057683.1
CDS214..1008
Misc Feature(1)190..192(+)
Misc Feature(2)214..1005(+)
Misc Feature(3)544..546(+)
Exon (1)1..199
Gene:MYOZ2
Gene Synonym:
Exon (2)200..289
Gene:MYOZ2
Gene Synonym:
Exon (3)290..459
Gene:MYOZ2
Gene Synonym:
Exon (4)460..589
Gene:MYOZ2
Gene Synonym:
Exon (5)590..773
Gene:MYOZ2
Gene Synonym:
Exon (6)774..2597
Gene:MYOZ2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_016599
Organism Homo sapiens (human)
Definition Homo sapiens myozenin 2 (MYOZ2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_016599

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGCTATCAC ATAATACTAT GATGAAGCAG AGAAAACAGC AAGCAACAGC CATCATGAAG 
GAAGTCCATG GAAATGATGT TGATGGCATG GACCTGGGCA AAAAGGTCAG CATCCCCAGA
GACATCATGT TGGAAGAATT ATCCCATCTC AGTAACCGTG GTGCCAGGCT ATTTAAGATG
CGTCAAAGAA GATCTGACAA ATACACATTT GAAAATTTCC AGTATCAATC TAGAGCACAA
ATAAATCACA GTATTGCTAT GCAGAATGGG AAAGTGGATG GAAGTAACTT GGAAGGTGGT
TCGCAGCAAG CCCCCTTGAC TCCTCCCAAC ACCCCAGATC CACGAAGCCC TCCAAATCCA
GACAACATTG CTCCAGGATA TTCTGGACCA CTGAAGGAAA TTCCTCCTGA AAAATTCAAC
ACCACAGCTG TCCCTAAGTA CTATCAATCT CCCTGGGAAC AAGCCATTAG CAATGATCCG
GAGCTTTTAG AGGCTTTATA TCCTAAACTT TTCAAGCCTG AAGGAAAGGC AGAACTGCCT
GATTACAGGA GCTTTAACAG GGTTGCCACA CCATTTGGAG GTTTTGAAAA AGCATCAAGA
ATGGTTAAAT TTAAAGTTCC AGATTTTGAG CTACTATTGC TAACAGATCC CAGGTTTATG
TCCTTTGTCA ATCCCCTTTC TGGCAGACGG TCCTTTAATA GGACTCCTAA GGGATGGATA
TCTGAGAATA TTCCTATAGT GATAACAACC GAACCTACAG ATGATACCAC TGTACCAGAA
TCAGAAGACC TATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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