The following PEX12 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PEX12 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 1080bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||peroxisome assembly protein 12
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DA298874.1, U91521.1,
BC031085.1 and AI341587.1.
This sequence is a reference standard in the RefSeqGene project.
On Aug 14, 2008 this sequence version replaced gi:4505720.
Summary: This gene belongs to the peroxin-12 family. Peroxins
(PEXs) are proteins that are essential for the assembly of
functional peroxisomes. The peroxisome biogenesis disorders (PBDs)
are a group of genetically heterogeneous autosomal recessive,
lethal diseases characterized by multiple defects in peroxisome
function. The peroxisomal biogenesis disorders are a heterogeneous
group with at least 14 complementation groups and with more than 1
phenotype being observed in cases falling into particular
complementation groups. Although the clinical features of PBD
patients vary, cells from all PBD patients exhibit a defect in the
import of one or more classes of peroxisomal matrix proteins into
the organelle. Defects in this gene are a cause of Zellweger
syndrome (ZWS). [provided by RefSeq, Oct 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: U91521.1, BC031085.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.