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PGAM2 cDNA ORF clone, Homo sapiens (human)

Gene Symbol PGAM2
Entrez Gene ID 5224
Full Name phosphoglycerate mutase 2 (muscle)
Synonyms GSD10, PGAM-M, PGAMM
General protein information
Preferred Names
phosphoglycerate mutase 2
Names
phosphoglycerate mutase 2
BPG-dependent PGAM 2
phosphoglycerate mutase isozyme M
muscle-specific phosphoglycerate mutase
NP_000281.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

7

7p13-p12

Summary Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X. [provided by RefSeq, Sep 2009]. lac of sum
Disorder MIM:

612931

Disorder Html: Glycogen storage disease X, 261670 (3)

mRNA and Protein(s)

mRNA Protein Name
XM_011515426 XP_011513728 phosphoglycerate mutase 2 isoform X1
NM_000290 NP_000281 phosphoglycerate mutase 2



Homo sapiens (human) PGAM2 NP_000281.2
Pan troglodytes (chimpanzee) PGAM2 XP_001143059.1
Macaca mulatta (Rhesus monkey) PGAM2 XP_001116220.1
Canis lupus familiaris (dog) PGAM2 XP_532718.2
Bos taurus (cattle) PGAM2 NP_001033200.1
Mus musculus (house mouse) Pgam2 NP_061358.1
Rattus norvegicus (Norway rat) Pgam2 NP_059024.1
Danio rerio (zebrafish) pgam2 NP_957318.1
Drosophila melanogaster (fruit fly) Pglym87 NP_652041.2
Xenopus (Silurana) tropicalis (western clawed frog) pgam2 NP_001005665.1


The following PGAM2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PGAM2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu59639 XM_011515426 PREDICTED: Homo sapiens phosphoglycerate mutase 2 (muscle) (PGAM2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu19214
NM_000290 Homo sapiens phosphoglycerate mutase 2 (muscle) (PGAM2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
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30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu59639
Clone ID Related Accession (Same CDS sequence) XM_011515426
Accession Version XM_011515426.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 444bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product phosphoglycerate mutase 2 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_007819.18) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGGCCACTC ACCGCCTCGT GATGGTCCGG CACGGCGAGA GCACATGGAA CCAGGAGAAC 
CGTTTCTGTG GCTGGTTCGA TGCAGAGCTG AGTGAAAAGG GGACCGAGGA GGCCAAGCGG
GGAGCCAAGG CCATCAAGGA TGCCAAGATG GAGTTTGACA TCTGCTACAC GTCAGTGCTG
AAGCGGGCCA TCCGCACCCT CTGGGCCATC CTGGACGGCA CGGACCAGAT GTGGCTGCCT
GTGGTGCGCA CTTGGCGCCT CAATGAGCGG CATTACGGGG GCCTCACAGG CCTCAACAAG
GCAGAAACGG CCGCCAAGCA CGGGGAGGAG CAGGTGAAGA TCTGGAGGCG CTCCTTCGAC
ATCCCGCCGC CCCCGATGGA CGAGAAGCAC CCCTACTACA ACTCCATTAG CAAGGGATGT
CAGACCAGGC GATCATGGAG CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011513728.1
CDS444..887
Misc Feature(1)456..>710(+)
Misc Feature(2)471..629(+)
Translation

Target ORF information:

RefSeq Version XM_011515426
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens phosphoglycerate mutase 2 (muscle) (PGAM2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011515426

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCCACTC ACCGCCTCGT GATGGTCCGG CACGGCGAGA GCACATGGAA CCAGGAGAAC 
CGTTTCTGTG GCTGGTTCGA TGCAGAGCTG AGTGAAAAGG GGACCGAGGA GGCCAAGCGG
GGAGCCAAGG CCATCAAGGA TGCCAAGATG GAGTTTGACA TCTGCTACAC GTCAGTGCTG
AAGCGGGCCA TCCGCACCCT CTGGGCCATC CTGGACGGCA CGGACCAGAT GTGGCTGCCT
GTGGTGCGCA CTTGGCGCCT CAATGAGCGG CATTACGGGG GCCTCACAGG CCTCAACAAG
GCAGAAACGG CCGCCAAGCA CGGGGAGGAG CAGGTGAAGA TCTGGAGGCG CTCCTTCGAC
ATCCCGCCGC CCCCGATGGA CGAGAAGCAC CCCTACTACA ACTCCATTAG CAAGGGATGT
CAGACCAGGC GATCATGGAG CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19214
Clone ID Related Accession (Same CDS sequence) NM_000290
Accession Version NM_000290.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 762bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product phosphoglycerate mutase 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CT002473.1 and BC001904.1. This sequence is a reference standard in the RefSeqGene project. On Sep 25, 2009 this sequence version replaced gi:50593009. ##Evidence-Data-START## Transcript exon combination :: BC001904.1, BF340226.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGCCACTC ACCGCCTCGT GATGGTCCGG CACGGCGAGA GCACATGGAA CCAGGAGAAC 
CGTTTCTGTG GCTGGTTCGA TGCAGAGCTG AGTGAAAAGG GGACCGAGGA GGCCAAGCGG
GGAGCCAAGG CCATCAAGGA TGCCAAGATG GAGTTTGACA TCTGCTACAC GTCAGTGCTG
AAGCGGGCCA TCCGCACCCT CTGGGCCATC CTGGACGGCA CGGACCAGAT GTGGCTGCCT
GTGGTGCGCA CTTGGCGCCT CAATGAGCGG CATTACGGGG GCCTCACAGG CCTCAACAAG
GCAGAAACGG CCGCCAAGCA CGGGGAGGAG CAGGTGAAGA TCTGGAGGCG CTCCTTCGAC
ATCCCGCCGC CCCCGATGGA CGAGAAGCAC CCCTACTACA ACTCCATTAG CAAGGAGCGT
CGGTACGCAG GCCTGAAGCC CGGGGAACTC CCCACCTGCG AGAGCCTCAA GGACACCATT
GCCCGGGCCC TGCCCTTCTG GAACGAGGAG ATTGTTCCCC AGATCAAGGC CGGCAAGCGA
GTGCTCATTG CAGCCCACGG GAACAGCCTG CGGGGCATTG TCAAGCACCT GGAAGGGATG
TCAGACCAGG CGATCATGGA GCTGAACCTG CCCACGGGGA TCCCCATTGT GTATGAGCTG
AACAAGGAGC TGAAGCCCAC CAAGCCCATG CAGTTCCTGG GTGATGAGGA AACGGTGCGG
AAGGCCATGG AGGCTGTGGC TGCCCAGGGC AAGGCCAAGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000281.2
CDS59..820
Misc Feature(1)71..742(+)
Misc Feature(2)86..619(+)
Misc Feature(3)242..244(+)
Exon (1)1..472
Gene:PGAM2
Gene Synonym:
Exon (2)473..653
Gene:PGAM2
Gene Synonym:
Exon (3)654..857
Gene:PGAM2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000290
Organism Homo sapiens (human)
Definition Homo sapiens phosphoglycerate mutase 2 (muscle) (PGAM2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000290

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGCCACTC ACCGCCTCGT GATGGTCCGG CACGGCGAGA GCACATGGAA CCAGGAGAAC 
CGTTTCTGTG GCTGGTTCGA TGCAGAGCTG AGTGAAAAGG GGACCGAGGA GGCCAAGCGG
GGAGCCAAGG CCATCAAGGA TGCCAAGATG GAGTTTGACA TCTGCTACAC GTCAGTGCTG
AAGCGGGCCA TCCGCACCCT CTGGGCCATC CTGGACGGCA CGGACCAGAT GTGGCTGCCT
GTGGTGCGCA CTTGGCGCCT CAATGAGCGG CATTACGGGG GCCTCACAGG CCTCAACAAG
GCAGAAACGG CCGCCAAGCA CGGGGAGGAG CAGGTGAAGA TCTGGAGGCG CTCCTTCGAC
ATCCCGCCGC CCCCGATGGA CGAGAAGCAC CCCTACTACA ACTCCATTAG CAAGGAGCGT
CGGTACGCAG GCCTGAAGCC CGGGGAACTC CCCACCTGCG AGAGCCTCAA GGACACCATT
GCCCGGGCCC TGCCCTTCTG GAACGAGGAG ATTGTTCCCC AGATCAAGGC CGGCAAGCGA
GTGCTCATTG CAGCCCACGG GAACAGCCTG CGGGGCATTG TCAAGCACCT GGAAGGGATG
TCAGACCAGG CGATCATGGA GCTGAACCTG CCCACGGGGA TCCCCATTGT GTATGAGCTG
AACAAGGAGC TGAAGCCCAC CAAGCCCATG CAGTTCCTGG GTGATGAGGA AACGGTGCGG
AAGGCCATGG AGGCTGTGGC TGCCCAGGGC AAGGCCAAGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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