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PHEX phosphate regulating endopeptidase homolog, X-linked [Homo sapiens (human)]

Gene Symbol PHEX
Entrez Gene ID 5251
Full Name phosphate regulating endopeptidase homolog, X-linked
Synonyms HPDR, HPDR1, HYP, HYP1, LXHR, PEX, XLH
General protein information
Preferred Names
phosphate-regulating neutral endopeptidase
Names
phosphate-regulating neutral endopeptidase
metalloendopeptidase homolog PEX
X-linked hypophosphatemia protein
vitamin D-resistant hypophosphatemic rickets protein
phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xp22.2-p22.1

Summary The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]. lac of sum
Disorder MIM:

300550

Disorder Html: Hypophosphatemic rickets, X-linked dominant, 307800 (3)





The following PHEX gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PHEX gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu59658 XM_011545533 PREDICTED: Homo sapiens phosphate regulating endopeptidase homolog, X-linked (PHEX), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $319
OHu59658 XM_011545534 PREDICTED: Homo sapiens phosphate regulating endopeptidase homolog, X-linked (PHEX), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $319
OHu59659 XM_011545535 PREDICTED: Homo sapiens phosphate regulating endopeptidase homolog, X-linked (PHEX), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319
OHu59660 XM_011545536 PREDICTED: Homo sapiens phosphate regulating endopeptidase homolog, X-linked (PHEX), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $319
OHu21896 NM_000444 Homo sapiens phosphate regulating endopeptidase homolog, X-linked (PHEX), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$265.3
$379
OHu20451 NM_001282754 Homo sapiens phosphate regulating endopeptidase homolog, X-linked (PHEX), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu59658
Accession Version XM_011545533.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1494bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product phosphate-regulating neutral endopeptidase isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167197.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGTGGATA CTGCCGTGCT TTTAGGAGCT AACAGTTCCA GAGCAGAGCA TGACATGAAG 
TCAGTGCTCA GATTGGAAAT TAAGATAGCT GAGATAATGA TTCCACATGA AAACCGAACC
AGCGAGGCCA TGTACAACAA AATGAACATT TCTGAACTGA GTGCTATGAT TCCCCAGTTC
GACTGGCTGG GCTACATCAA GAAGGTCATT GACACCAGAC TCTACCCCCA TCTGAAAGAC
ATCAGCCCCT CCGAGAATGT GGTGGTCCGC GTCCCGCAGT ACTTTAAAGA TTTGTTTAGG
ATATTAGGGT CTGAGAGAAA GAAGACCATT GCCAACTATT TGGTGTGGAG AATGGTTTAT
TCCAGAATTC CAAACCTTAG CAGGCGCTTT CAGTATAGAT GGCTGGAATT CTCAAGGGTA
ATCCAGGGGA CCACAACTTT GCTGCCTCAA TGGGACAAAT GTGTAAACTT TATTGAAAGT
GCCCTCCCTT ATGTTGTTGG AAAGATGTTT GTAGATGTGT ACTTCCAGGA AGATAAGAAG
GAAATGATGG AGGAATTGGT TGAGGGCGTT CGCTGGGCCT TTATTGACAT GCTAGAGAAA
GAAAATGAGT GGATGGATGC AGGAACGAAA AGGAAAGCCA AAGAAAAGGC GAGAGCTGTT
TTGGCAAAAG TTGGCTATCC AGAGTTTATA ATGAATGATA CTCATGTTAA TGAAGACCTC
AAAGCTATCA AGTTTTCAGA AGCCGACTAC TTTGGCAACG TCCTACAAAC TCGCAAGTAT
TTAGCACAGT CTGATTTCTT CTGGCTAAGA AAAGCCGTTC CAAAAACAGA GTGGTTTACA
AATCCGACGA CTGTCAATGC CTTCTACAGT GCATCCACCA ACCAGATCCG ATTTCCAGCA
GGAGAGCTCC AGAAGCCTTT CTTTTGGGGA ACAGAATATC CTCGATCTCT GAGTTATGGT
GCTATAGGAG TAATTGTCGG ACATGAATTT ACACATGGAT TTGATAATAA TGGTAGAAAA
TATGATAAAA ATGGAAACCT GGATCCTTGG TGGTCTACTG AATCAGAAGA AAAGTTTAAG
GAAAAAACAA AATGCATGAT TAACCAGTAT AGCAACTATT ATTGGAAGAA AGCTGGCTTA
AATGTCAAGG GGAAGAGGAC CCTGGGAGAA AATATTGCTG ATAATGGAGG CCTGCGGGAA
GCTTTTAGGG CTTACAGGAA ATGGATAAAT GACAGAAGGC AGGGACTTGA GGAGCCTCTT
CTACCAGGCA TCACATTCAC CAACAACCAG CTCTTCTTCC TGAGTTATGC TCATGTGAGG
TGCAATTCCT ACAGACCAGA AGCTGCCCGA GAACAAGTCC AAATTGGTGC TCACAGTCCC
CCTCAGTTTA GGGTCAATGG TGCAATTAGT AACTTTGAAG AATTCCAGAA AGCTTTTAAC
TGTCCACCCA ATTCCACGAT GAACAGAGGC ATGGACTCCT GCCGACTCTG GTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011543835.1
CDS128..1621
Misc Feature(1)128..1612(+)
Misc Feature(2)983..1519(+)
Misc Feature(3)1109..1297(+)
Translation
Position Chain Variation Link
13 13 a, g dbSNP:138498455
44 44 a, g dbSNP:749327791
49 49 a, g dbSNP:771529993
61 61 c, g, t dbSNP:149487757
62 62 a, g dbSNP:376291775
81 81 a, t dbSNP:775148284
95 95 a, g dbSNP:760319054
96 96 c, g dbSNP:144007621
101 101 c, t dbSNP:763517570
111 111 a, g dbSNP:779431331
126 126 c, t dbSNP:267606945
130 130 a, g dbSNP:267606946
138 138 c, g dbSNP:746328622
140 140 c, g dbSNP:772441926
142 142 c, t dbSNP:142833404
153 153 a, g dbSNP:113219043
168 168 a, g dbSNP:775766235
191 191 a, g dbSNP:747331129
192 192 c, t dbSNP:768413746
198 198 a, g dbSNP:776124957
200 200 c, t dbSNP:761416628
201 201 a, t dbSNP:137853268
211 211 a, g dbSNP:147430384
220 220 a, g dbSNP:773293894
231 231 c, t dbSNP:746436151
238 238 a, g dbSNP:139771307
246 246 c, t dbSNP:768862054
247 247 a, c dbSNP:776367122
250 250 c, t dbSNP:772573976
251 251 a, g dbSNP:747696209
255 255 c, g dbSNP:769430757
256 256 -, cc dbSNP:193922460
266 266 a, g dbSNP:772921325
270 270 c, t dbSNP:762535711
272 272 a, c dbSNP:199893153
274 274 c, t dbSNP:142755818
275 275 a, g dbSNP:759411768
279 279 a, c dbSNP:767171186
281 281 a, g dbSNP:754106853
289 289 c, t dbSNP:150619847
293 293 a, g dbSNP:372663150
307 307 c, t dbSNP:760451270
308 308 a, g dbSNP:757539874
316 316 g, t dbSNP:750613071
318 318 g, t dbSNP:763042990
319 319 c, g dbSNP:766310950
328 328 a, g, t dbSNP:373261521
342 342 c, t dbSNP:199965602
344 344 a, c dbSNP:781713539
353 353 c, g dbSNP:201383931
360 360 g, t dbSNP:756512186
367 367 c, t dbSNP:139749399
379 379 c, t dbSNP:775973349
380 380 a, g dbSNP:770491624
385 385 c, t dbSNP:149793221
392 392 g, t dbSNP:745382329
395 395 c, t dbSNP:761575825
396 396 a, g dbSNP:376461141
397 397 c, t dbSNP:746847960
398 398 a, g dbSNP:768400503
413 413 a, g dbSNP:773436322
416 416 c, g dbSNP:763094620
433 433 a, g dbSNP:766616716
448 448 a, g dbSNP:774349246
450 450 a, g dbSNP:185862803
454 454 a, c dbSNP:753547432
464 464 c, t dbSNP:756929627
482 482 a, g dbSNP:759015845
489 489 c, t dbSNP:778616699
490 490 c, t dbSNP:753296824
511 511 a, g dbSNP:757894404
520 520 a, g dbSNP:779998335
525 525 a, g dbSNP:373233283
533 533 a, g dbSNP:746890776
553 553 a, g dbSNP:774598902
556 556 c, g dbSNP:371115510
567 567 c, t dbSNP:767652424
573 573 c, t dbSNP:145778165
577 577 a, g dbSNP:151234075
591 591 c, t dbSNP:764695823
596 596 c, t dbSNP:754314481
619 619 c, t dbSNP:757620472
632 632 a, g dbSNP:764839343
638 638 a, g dbSNP:750052547
649 649 c, t dbSNP:375729152
655 655 g, t dbSNP:757869310
694 694 c, t dbSNP:769336836
695 695 a, g dbSNP:777167473
715 715 c, t dbSNP:144911719
730 730 a, c dbSNP:202164519
745 745 c, t dbSNP:370746437
751 751 a, g dbSNP:750047503
753 753 c, t dbSNP:374873766
754 754 a, g dbSNP:77710864
766 766 c, g dbSNP:751117913
775 775 c, g dbSNP:754449807
777 777 c, t dbSNP:375593493
797 797 a, g dbSNP:766990714
808 808 a, g dbSNP:141436752
817 817 a, g dbSNP:756146878
827 827 a, g dbSNP:777560709
832 832 c, t dbSNP:765101791
834 834 a, t dbSNP:369896990
841 841 a, t dbSNP:371934258
852 852 a, c dbSNP:747180101
869 869 a, g dbSNP:765067632
870 870 a, c dbSNP:751837244
872 872 a, g dbSNP:373235530
873 873 a, g dbSNP:755284765
886 886 c, t dbSNP:764771688
887 887 a, g dbSNP:781248973
892 892 a, c dbSNP:748298612
902 902 a, c dbSNP:753522380
903 903 a, c dbSNP:778363445
916 916 c, g dbSNP:201266084
925 925 a, c dbSNP:749734873
960 960 a, g dbSNP:193922455
966 966 c, t dbSNP:767812044
987 987 c, t dbSNP:199935279
997 997 c, t dbSNP:752810184
1026 1026 c, t dbSNP:773244112
1027 1027 a, g dbSNP:143427381
1035 1035 c, t dbSNP:137853270
1046 1046 c, t dbSNP:762828809
1051 1051 c, t dbSNP:766026766
1070 1070 a, c, t dbSNP:137853271
1071 1071 a, g dbSNP:760870713
1073 1073 a, t dbSNP:768470624
1075 1075 c, t dbSNP:112728394
1093 1093 a, g dbSNP:780959710
1097 1097 a, g dbSNP:747692520
1105 1105 c, t dbSNP:769379550
1114 1114 a, g dbSNP:773291977
1119 1119 c, t dbSNP:762728667
1134 1134 a, t dbSNP:772130004
1144 1144 a, g dbSNP:781013156
1165 1165 c, t dbSNP:747743987
1180 1180 g, t dbSNP:755686699
1189 1189 a, g dbSNP:146055519
1190 1190 a, t dbSNP:748815816
1237 1237 c, t dbSNP:375441152
1287 1287 a, c dbSNP:111636676
1288 1288 a, c dbSNP:201343697
1289 1289 a, c dbSNP:756017274
1312 1312 c, t dbSNP:755885733
1320 1320 c, t dbSNP:193922456
1321 1321 a, g dbSNP:777456871
1323 1323 a, g dbSNP:748792378
1333 1333 c, t dbSNP:756752961
1352 1352 a, g dbSNP:774626712
1370 1370 g, t dbSNP:193922457
1383 1383 a, c dbSNP:759663012
1392 1392 a, c, t dbSNP:199517401
1396 1396 a, c dbSNP:760972913
1400 1400 a, c, g dbSNP:112577880
1401 1401 c, g dbSNP:764465237
1408 1408 c, t dbSNP:766459849
1423 1423 c, g dbSNP:373674171
1427 1427 a, c dbSNP:764784243
1439 1439 a, c dbSNP:200733697
1472 1472 g, t dbSNP:746918835
1479 1479 a, t dbSNP:747487296
1512 1512 a, g dbSNP:769039646
1522 1522 c, g dbSNP:772854418
1524 1524 a, c, g dbSNP:191028600
1532 1532 a, g dbSNP:766003166
1534 1534 c, g, t dbSNP:372307955
1544 1544 a, g dbSNP:767518128
1559 1559 g, t dbSNP:752729907
1567 1567 a, c dbSNP:376952568
1576 1576 c, t dbSNP:755989604
1578 1578 a, g dbSNP:367955819
1584 1584 c, t dbSNP:371825581
1585 1585 a, g dbSNP:140742016
1606 1606 c, g dbSNP:150112217
1611 1611 a, g dbSNP:138773278
1615 1615 c, g dbSNP:747154530
1622 1622 a, c dbSNP:754974866
1629 1629 a, g dbSNP:781727969
1640 1640 a, g dbSNP:374774539
1646 1646 c, t dbSNP:770279983
1668 1668 c, t dbSNP:370155243
1669 1669 a, g dbSNP:765479131
1679 1679 c, t dbSNP:183223600
1692 1692 a, g dbSNP:186466573
1731 1731 a, t dbSNP:780324969
1788 1788 a, g dbSNP:751689587
1828 1828 a, g dbSNP:755389049
1839 1839 a, c dbSNP:141594056
1843 1843 c, t dbSNP:748724335
1846 1846 a, g dbSNP:770275990
1848 1848 c, g dbSNP:765787001
1903 1903 g, t dbSNP:373526963
1926 1926 a, g dbSNP:189715720
1948 1948 c, g dbSNP:748836233
1956 1956 a, g dbSNP:770308822
1960 1960 a, g dbSNP:773553690
1982 1982 c, t dbSNP:182654518
2009 2009 a, g dbSNP:759086924
2046 2046 a, g dbSNP:775420101
2077 2077 a, g dbSNP:147507544
2093 2093 g, t dbSNP:763522632
2101 2101 c, t dbSNP:766900352
2149 2149 a, g dbSNP:113813269
2195 2195 c, g dbSNP:776361459
2212 2212 a, g dbSNP:369147272
2292 2292 g, t dbSNP:751959768
2309 2309 -, tgag dbSNP:750660265
2320 2320 c, g dbSNP:145080586
2326 2326 -, a dbSNP:766317343
2389 2389 c, t dbSNP:754747451
2398 2398 a, c dbSNP:188175876
2441 2441 a, g dbSNP:5951739
2444 2444 a, g dbSNP:41309575
2469 2469 -, t dbSNP:753078908
2493 2493 c, g, t dbSNP:376254574
2494 2494 a, g dbSNP:149673099
2516 2516 a, g dbSNP:749711087
2519 2519 c, t dbSNP:145476860
2541 2541 a, c dbSNP:192770679
2553 2553 a, g dbSNP:183619109
2569 2569 c, t dbSNP:187522891
2599 2599 -, t dbSNP:200473244
2601 2601 a, tagtgcaaag dbSNP:386824235
2601 2601 -, tagtgcaaa dbSNP:200544019
2601 2601 -, tagtgcaa dbSNP:79379908
2603 2603 -, gtgcaaag dbSNP:199638664
2604 2604 a, t dbSNP:777794098
2605 2605 a, g dbSNP:749259065
2608 2608 -, aag dbSNP:746800228
2610 2610 a, g dbSNP:200248764
2736 2736 a, g dbSNP:192098973
2742 2742 a, c dbSNP:757161203
2768 2768 a, g dbSNP:148478140
2776 2776 c, t dbSNP:761631760
2845 2845 c, t dbSNP:369535826
2876 2876 -, gtgtgtgtgtgtggtgtgtgtgt dbSNP:766550946
2877 2877 -, gtgtgtgtgt dbSNP:771619032
2877 2877 -, gt dbSNP:749752907
2908 2908 -, gtgtgtgtgt dbSNP:59496974
2926 2926 g, t dbSNP:774285492
2951 2951 c, t dbSNP:16981889
3029 3029 c, t dbSNP:184539861
3099 3099 a, t dbSNP:752876880
3110 3110 a, t dbSNP:377467619
3111 3111 -, a dbSNP:540966419
3123 3123 -, aat dbSNP:762309910
3124 3124 -, a, at dbSNP:71879575
3125 3125 a, t dbSNP:59285690
3125 3125 -, t dbSNP:372076236
3127 3127 a, t dbSNP:59180400
3127 3127 -, t dbSNP:370627436
3162 3162 a, c dbSNP:764345252
3165 3165 c, t dbSNP:5951740
3188 3188 g, t dbSNP:753777813
3272 3272 c, t dbSNP:757697615
3282 3282 c, t dbSNP:5951741
3303 3303 a, t dbSNP:5951742
3369 3369 c, g dbSNP:191203770
3382 3382 c, g dbSNP:745656887
3406 3406 a, g dbSNP:145670027
3409 3409 g, t dbSNP:768926927
3500 3500 c, g dbSNP:184499919
3581 3581 a, g dbSNP:748292420
3612 3612 a, g dbSNP:373843573
3632 3632 -, tcac dbSNP:776288532
3640 3640 c, t dbSNP:769805151
3751 3751 c, t dbSNP:773406106
3771 3771 -, caaa dbSNP:559255193
3771 3771 a, c dbSNP:1894417
3782 3782 a, g dbSNP:766992148
3810 3810 c, t dbSNP:189815560
3823 3823 c, g dbSNP:773135056
3848 3848 c, t dbSNP:759647942
3882 3882 a, g dbSNP:759926909
3886 3886 c, t dbSNP:772094808
3891 3891 a, g dbSNP:141005414
3923 3923 a, c dbSNP:1894418
3934 3934 a, g dbSNP:138745617
4064 4064 a, g dbSNP:752248178
4083 4083 c, g dbSNP:760339525
4095 4095 g, t dbSNP:149429660
4139 4139 a, g dbSNP:718302
4148 4148 a, c dbSNP:377429675
4200 4200 c, t dbSNP:147114489
4201 4201 a, g dbSNP:750920468
4215 4215 a, g dbSNP:758003630
4228 4228 a, t dbSNP:138443284
4271 4271 a, c dbSNP:751295282
4277 4277 a, c dbSNP:763558376
4306 4306 a, g dbSNP:144006455
4356 4356 -, cctc dbSNP:773840982
4388 4388 c, t dbSNP:186570524
4483 4483 a, c dbSNP:769591275
4599 4599 a, g dbSNP:147159870
4638 4638 a, g dbSNP:148632928
4648 4648 g, t dbSNP:141223944
4688 4688 c, t dbSNP:775541115
4708 4708 a, c dbSNP:150716965
4755 4755 -, a dbSNP:779634495
4759 4759 c, t dbSNP:768770074
4760 4760 a, g dbSNP:776842545
4761 4761 c, t dbSNP:139065358
4762 4762 c, t dbSNP:778752986
4771 4771 a, g dbSNP:144125698
4796 4796 a, t dbSNP:750231550
4825 4825 c, g dbSNP:751015608
4890 4890 c, t dbSNP:763520621
4908 4908 c, t dbSNP:146520078
4910 4910 c, t dbSNP:533345329
4933 4933 g, t dbSNP:57128317

Target ORF information:

RefSeq Version XM_011545533
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens phosphate regulating endopeptidase homolog, X-linked (PHEX), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011545533

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGTGGATA CTGCCGTGCT TTTAGGAGCT AACAGTTCCA GAGCAGAGCA TGACATGAAG 
TCAGTGCTCA GATTGGAAAT TAAGATAGCT GAGATAATGA TTCCACATGA AAACCGAACC
AGCGAGGCCA TGTACAACAA AATGAACATT TCTGAACTGA GTGCTATGAT TCCCCAGTTC
GACTGGCTGG GCTACATCAA GAAGGTCATT GACACCAGAC TCTACCCCCA TCTGAAAGAC
ATCAGCCCCT CCGAGAATGT GGTGGTCCGC GTCCCGCAGT ACTTTAAAGA TTTGTTTAGG
ATATTAGGGT CTGAGAGAAA GAAGACCATT GCCAACTATT TGGTGTGGAG AATGGTTTAT
TCCAGAATTC CAAACCTTAG CAGGCGCTTT CAGTATAGAT GGCTGGAATT CTCAAGGGTA
ATCCAGGGGA CCACAACTTT GCTGCCTCAA TGGGACAAAT GTGTAAACTT TATTGAAAGT
GCCCTCCCTT ATGTTGTTGG AAAGATGTTT GTAGATGTGT ACTTCCAGGA AGATAAGAAG
GAAATGATGG AGGAATTGGT TGAGGGCGTT CGCTGGGCCT TTATTGACAT GCTAGAGAAA
GAAAATGAGT GGATGGATGC AGGAACGAAA AGGAAAGCCA AAGAAAAGGC GAGAGCTGTT
TTGGCAAAAG TTGGCTATCC AGAGTTTATA ATGAATGATA CTCATGTTAA TGAAGACCTC
AAAGCTATCA AGTTTTCAGA AGCCGACTAC TTTGGCAACG TCCTACAAAC TCGCAAGTAT
TTAGCACAGT CTGATTTCTT CTGGCTAAGA AAAGCCGTTC CAAAAACAGA GTGGTTTACA
AATCCGACGA CTGTCAATGC CTTCTACAGT GCATCCACCA ACCAGATCCG ATTTCCAGCA
GGAGAGCTCC AGAAGCCTTT CTTTTGGGGA ACAGAATATC CTCGATCTCT GAGTTATGGT
GCTATAGGAG TAATTGTCGG ACATGAATTT ACACATGGAT TTGATAATAA TGGTAGAAAA
TATGATAAAA ATGGAAACCT GGATCCTTGG TGGTCTACTG AATCAGAAGA AAAGTTTAAG
GAAAAAACAA AATGCATGAT TAACCAGTAT AGCAACTATT ATTGGAAGAA AGCTGGCTTA
AATGTCAAGG GGAAGAGGAC CCTGGGAGAA AATATTGCTG ATAATGGAGG CCTGCGGGAA
GCTTTTAGGG CTTACAGGAA ATGGATAAAT GACAGAAGGC AGGGACTTGA GGAGCCTCTT
CTACCAGGCA TCACATTCAC CAACAACCAG CTCTTCTTCC TGAGTTATGC TCATGTGAGG
TGCAATTCCT ACAGACCAGA AGCTGCCCGA GAACAAGTCC AAATTGGTGC TCACAGTCCC
CCTCAGTTTA GGGTCAATGG TGCAATTAGT AACTTTGAAG AATTCCAGAA AGCTTTTAAC
TGTCCACCCA ATTCCACGAT GAACAGAGGC ATGGACTCCT GCCGACTCTG GTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu59658
Accession Version XM_011545534.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1494bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product phosphate-regulating neutral endopeptidase isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167197.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGTGGATA CTGCCGTGCT TTTAGGAGCT AACAGTTCCA GAGCAGAGCA TGACATGAAG 
TCAGTGCTCA GATTGGAAAT TAAGATAGCT GAGATAATGA TTCCACATGA AAACCGAACC
AGCGAGGCCA TGTACAACAA AATGAACATT TCTGAACTGA GTGCTATGAT TCCCCAGTTC
GACTGGCTGG GCTACATCAA GAAGGTCATT GACACCAGAC TCTACCCCCA TCTGAAAGAC
ATCAGCCCCT CCGAGAATGT GGTGGTCCGC GTCCCGCAGT ACTTTAAAGA TTTGTTTAGG
ATATTAGGGT CTGAGAGAAA GAAGACCATT GCCAACTATT TGGTGTGGAG AATGGTTTAT
TCCAGAATTC CAAACCTTAG CAGGCGCTTT CAGTATAGAT GGCTGGAATT CTCAAGGGTA
ATCCAGGGGA CCACAACTTT GCTGCCTCAA TGGGACAAAT GTGTAAACTT TATTGAAAGT
GCCCTCCCTT ATGTTGTTGG AAAGATGTTT GTAGATGTGT ACTTCCAGGA AGATAAGAAG
GAAATGATGG AGGAATTGGT TGAGGGCGTT CGCTGGGCCT TTATTGACAT GCTAGAGAAA
GAAAATGAGT GGATGGATGC AGGAACGAAA AGGAAAGCCA AAGAAAAGGC GAGAGCTGTT
TTGGCAAAAG TTGGCTATCC AGAGTTTATA ATGAATGATA CTCATGTTAA TGAAGACCTC
AAAGCTATCA AGTTTTCAGA AGCCGACTAC TTTGGCAACG TCCTACAAAC TCGCAAGTAT
TTAGCACAGT CTGATTTCTT CTGGCTAAGA AAAGCCGTTC CAAAAACAGA GTGGTTTACA
AATCCGACGA CTGTCAATGC CTTCTACAGT GCATCCACCA ACCAGATCCG ATTTCCAGCA
GGAGAGCTCC AGAAGCCTTT CTTTTGGGGA ACAGAATATC CTCGATCTCT GAGTTATGGT
GCTATAGGAG TAATTGTCGG ACATGAATTT ACACATGGAT TTGATAATAA TGGTAGAAAA
TATGATAAAA ATGGAAACCT GGATCCTTGG TGGTCTACTG AATCAGAAGA AAAGTTTAAG
GAAAAAACAA AATGCATGAT TAACCAGTAT AGCAACTATT ATTGGAAGAA AGCTGGCTTA
AATGTCAAGG GGAAGAGGAC CCTGGGAGAA AATATTGCTG ATAATGGAGG CCTGCGGGAA
GCTTTTAGGG CTTACAGGAA ATGGATAAAT GACAGAAGGC AGGGACTTGA GGAGCCTCTT
CTACCAGGCA TCACATTCAC CAACAACCAG CTCTTCTTCC TGAGTTATGC TCATGTGAGG
TGCAATTCCT ACAGACCAGA AGCTGCCCGA GAACAAGTCC AAATTGGTGC TCACAGTCCC
CCTCAGTTTA GGGTCAATGG TGCAATTAGT AACTTTGAAG AATTCCAGAA AGCTTTTAAC
TGTCCACCCA ATTCCACGAT GAACAGAGGC ATGGACTCCT GCCGACTCTG GTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011543836.1
CDS157..1650
Misc Feature(1)157..1641(+)
Misc Feature(2)1012..1548(+)
Misc Feature(3)1138..1326(+)
Translation
Position Chain Variation Link
73 73 a, g dbSNP:749327791
78 78 a, g dbSNP:771529993
90 90 c, g, t dbSNP:149487757
91 91 a, g dbSNP:376291775
110 110 a, t dbSNP:775148284
124 124 a, g dbSNP:760319054
125 125 c, g dbSNP:144007621
130 130 c, t dbSNP:763517570
140 140 a, g dbSNP:779431331
155 155 c, t dbSNP:267606945
159 159 a, g dbSNP:267606946
167 167 c, g dbSNP:746328622
169 169 c, g dbSNP:772441926
171 171 c, t dbSNP:142833404
182 182 a, g dbSNP:113219043
197 197 a, g dbSNP:775766235
220 220 a, g dbSNP:747331129
221 221 c, t dbSNP:768413746
227 227 a, g dbSNP:776124957
229 229 c, t dbSNP:761416628
230 230 a, t dbSNP:137853268
240 240 a, g dbSNP:147430384
249 249 a, g dbSNP:773293894
260 260 c, t dbSNP:746436151
267 267 a, g dbSNP:139771307
275 275 c, t dbSNP:768862054
276 276 a, c dbSNP:776367122
279 279 c, t dbSNP:772573976
280 280 a, g dbSNP:747696209
284 284 c, g dbSNP:769430757
285 285 -, cc dbSNP:193922460
295 295 a, g dbSNP:772921325
299 299 c, t dbSNP:762535711
301 301 a, c dbSNP:199893153
303 303 c, t dbSNP:142755818
304 304 a, g dbSNP:759411768
308 308 a, c dbSNP:767171186
310 310 a, g dbSNP:754106853
318 318 c, t dbSNP:150619847
322 322 a, g dbSNP:372663150
336 336 c, t dbSNP:760451270
337 337 a, g dbSNP:757539874
345 345 g, t dbSNP:750613071
347 347 g, t dbSNP:763042990
348 348 c, g dbSNP:766310950
357 357 a, g, t dbSNP:373261521
371 371 c, t dbSNP:199965602
373 373 a, c dbSNP:781713539
382 382 c, g dbSNP:201383931
389 389 g, t dbSNP:756512186
396 396 c, t dbSNP:139749399
408 408 c, t dbSNP:775973349
409 409 a, g dbSNP:770491624
414 414 c, t dbSNP:149793221
421 421 g, t dbSNP:745382329
424 424 c, t dbSNP:761575825
425 425 a, g dbSNP:376461141
426 426 c, t dbSNP:746847960
427 427 a, g dbSNP:768400503
442 442 a, g dbSNP:773436322
445 445 c, g dbSNP:763094620
462 462 a, g dbSNP:766616716
477 477 a, g dbSNP:774349246
479 479 a, g dbSNP:185862803
483 483 a, c dbSNP:753547432
493 493 c, t dbSNP:756929627
511 511 a, g dbSNP:759015845
518 518 c, t dbSNP:778616699
519 519 c, t dbSNP:753296824
540 540 a, g dbSNP:757894404
549 549 a, g dbSNP:779998335
554 554 a, g dbSNP:373233283
562 562 a, g dbSNP:746890776
582 582 a, g dbSNP:774598902
585 585 c, g dbSNP:371115510
596 596 c, t dbSNP:767652424
602 602 c, t dbSNP:145778165
606 606 a, g dbSNP:151234075
620 620 c, t dbSNP:764695823
625 625 c, t dbSNP:754314481
648 648 c, t dbSNP:757620472
661 661 a, g dbSNP:764839343
667 667 a, g dbSNP:750052547
678 678 c, t dbSNP:375729152
684 684 g, t dbSNP:757869310
723 723 c, t dbSNP:769336836
724 724 a, g dbSNP:777167473
744 744 c, t dbSNP:144911719
759 759 a, c dbSNP:202164519
774 774 c, t dbSNP:370746437
780 780 a, g dbSNP:750047503
782 782 c, t dbSNP:374873766
783 783 a, g dbSNP:77710864
795 795 c, g dbSNP:751117913
804 804 c, g dbSNP:754449807
806 806 c, t dbSNP:375593493
826 826 a, g dbSNP:766990714
837 837 a, g dbSNP:141436752
846 846 a, g dbSNP:756146878
856 856 a, g dbSNP:777560709
861 861 c, t dbSNP:765101791
863 863 a, t dbSNP:369896990
870 870 a, t dbSNP:371934258
881 881 a, c dbSNP:747180101
898 898 a, g dbSNP:765067632
899 899 a, c dbSNP:751837244
901 901 a, g dbSNP:373235530
902 902 a, g dbSNP:755284765
915 915 c, t dbSNP:764771688
916 916 a, g dbSNP:781248973
921 921 a, c dbSNP:748298612
931 931 a, c dbSNP:753522380
932 932 a, c dbSNP:778363445
945 945 c, g dbSNP:201266084
954 954 a, c dbSNP:749734873
989 989 a, g dbSNP:193922455
995 995 c, t dbSNP:767812044
1016 1016 c, t dbSNP:199935279
1026 1026 c, t dbSNP:752810184
1055 1055 c, t dbSNP:773244112
1056 1056 a, g dbSNP:143427381
1064 1064 c, t dbSNP:137853270
1075 1075 c, t dbSNP:762828809
1080 1080 c, t dbSNP:766026766
1099 1099 a, c, t dbSNP:137853271
1100 1100 a, g dbSNP:760870713
1102 1102 a, t dbSNP:768470624
1104 1104 c, t dbSNP:112728394
1122 1122 a, g dbSNP:780959710
1126 1126 a, g dbSNP:747692520
1134 1134 c, t dbSNP:769379550
1143 1143 a, g dbSNP:773291977
1148 1148 c, t dbSNP:762728667
1163 1163 a, t dbSNP:772130004
1173 1173 a, g dbSNP:781013156
1194 1194 c, t dbSNP:747743987
1209 1209 g, t dbSNP:755686699
1218 1218 a, g dbSNP:146055519
1219 1219 a, t dbSNP:748815816
1266 1266 c, t dbSNP:375441152
1316 1316 a, c dbSNP:111636676
1317 1317 a, c dbSNP:201343697
1318 1318 a, c dbSNP:756017274
1341 1341 c, t dbSNP:755885733
1349 1349 c, t dbSNP:193922456
1350 1350 a, g dbSNP:777456871
1352 1352 a, g dbSNP:748792378
1362 1362 c, t dbSNP:756752961
1381 1381 a, g dbSNP:774626712
1399 1399 g, t dbSNP:193922457
1412 1412 a, c dbSNP:759663012
1421 1421 a, c, t dbSNP:199517401
1425 1425 a, c dbSNP:760972913
1429 1429 a, c, g dbSNP:112577880
1430 1430 c, g dbSNP:764465237
1437 1437 c, t dbSNP:766459849
1452 1452 c, g dbSNP:373674171
1456 1456 a, c dbSNP:764784243
1468 1468 a, c dbSNP:200733697
1501 1501 g, t dbSNP:746918835
1508 1508 a, t dbSNP:747487296
1541 1541 a, g dbSNP:769039646
1551 1551 c, g dbSNP:772854418
1553 1553 a, c, g dbSNP:191028600
1561 1561 a, g dbSNP:766003166
1563 1563 c, g, t dbSNP:372307955
1573 1573 a, g dbSNP:767518128
1588 1588 g, t dbSNP:752729907
1596 1596 a, c dbSNP:376952568
1605 1605 c, t dbSNP:755989604
1607 1607 a, g dbSNP:367955819
1613 1613 c, t dbSNP:371825581
1614 1614 a, g dbSNP:140742016
1635 1635 c, g dbSNP:150112217
1640 1640 a, g dbSNP:138773278
1644 1644 c, g dbSNP:747154530
1651 1651 a, c dbSNP:754974866
1658 1658 a, g dbSNP:781727969
1669 1669 a, g dbSNP:374774539
1675 1675 c, t dbSNP:770279983
1697 1697 c, t dbSNP:370155243
1698 1698 a, g dbSNP:765479131
1708 1708 c, t dbSNP:183223600
1721 1721 a, g dbSNP:186466573
1760 1760 a, t dbSNP:780324969
1817 1817 a, g dbSNP:751689587
1857 1857 a, g dbSNP:755389049
1868 1868 a, c dbSNP:141594056
1872 1872 c, t dbSNP:748724335
1875 1875 a, g dbSNP:770275990
1877 1877 c, g dbSNP:765787001
1932 1932 g, t dbSNP:373526963
1955 1955 a, g dbSNP:189715720
1977 1977 c, g dbSNP:748836233
1985 1985 a, g dbSNP:770308822
1989 1989 a, g dbSNP:773553690
2011 2011 c, t dbSNP:182654518
2038 2038 a, g dbSNP:759086924
2075 2075 a, g dbSNP:775420101
2106 2106 a, g dbSNP:147507544
2122 2122 g, t dbSNP:763522632
2130 2130 c, t dbSNP:766900352
2178 2178 a, g dbSNP:113813269
2224 2224 c, g dbSNP:776361459
2241 2241 a, g dbSNP:369147272
2321 2321 g, t dbSNP:751959768
2338 2338 -, tgag dbSNP:750660265
2349 2349 c, g dbSNP:145080586
2355 2355 -, a dbSNP:766317343
2418 2418 c, t dbSNP:754747451
2427 2427 a, c dbSNP:188175876
2470 2470 a, g dbSNP:5951739
2473 2473 a, g dbSNP:41309575
2498 2498 -, t dbSNP:753078908
2522 2522 c, g, t dbSNP:376254574
2523 2523 a, g dbSNP:149673099
2545 2545 a, g dbSNP:749711087
2548 2548 c, t dbSNP:145476860
2570 2570 a, c dbSNP:192770679
2582 2582 a, g dbSNP:183619109
2598 2598 c, t dbSNP:187522891
2628 2628 -, t dbSNP:200473244
2630 2630 a, tagtgcaaag dbSNP:386824235
2630 2630 -, tagtgcaaa dbSNP:200544019
2630 2630 -, tagtgcaa dbSNP:79379908
2632 2632 -, gtgcaaag dbSNP:199638664
2633 2633 a, t dbSNP:777794098
2634 2634 a, g dbSNP:749259065
2637 2637 -, aag dbSNP:746800228
2639 2639 a, g dbSNP:200248764
2765 2765 a, g dbSNP:192098973
2771 2771 a, c dbSNP:757161203
2797 2797 a, g dbSNP:148478140
2805 2805 c, t dbSNP:761631760
2874 2874 c, t dbSNP:369535826
2905 2905 -, gtgtgtgtgtgtggtgtgtgtgt dbSNP:766550946
2906 2906 -, gtgtgtgtgt dbSNP:771619032
2906 2906 -, gt dbSNP:749752907
2937 2937 -, gtgtgtgtgt dbSNP:59496974
2955 2955 g, t dbSNP:774285492
2980 2980 c, t dbSNP:16981889
3058 3058 c, t dbSNP:184539861
3128 3128 a, t dbSNP:752876880
3139 3139 a, t dbSNP:377467619
3140 3140 -, a dbSNP:540966419
3152 3152 -, aat dbSNP:762309910
3153 3153 -, a, at dbSNP:71879575
3154 3154 a, t dbSNP:59285690
3154 3154 -, t dbSNP:372076236
3156 3156 a, t dbSNP:59180400
3156 3156 -, t dbSNP:370627436
3191 3191 a, c dbSNP:764345252
3194 3194 c, t dbSNP:5951740
3217 3217 g, t dbSNP:753777813
3301 3301 c, t dbSNP:757697615
3311 3311 c, t dbSNP:5951741
3332 3332 a, t dbSNP:5951742
3398 3398 c, g dbSNP:191203770
3411 3411 c, g dbSNP:745656887
3435 3435 a, g dbSNP:145670027
3438 3438 g, t dbSNP:768926927
3529 3529 c, g dbSNP:184499919
3610 3610 a, g dbSNP:748292420
3641 3641 a, g dbSNP:373843573
3661 3661 -, tcac dbSNP:776288532
3669 3669 c, t dbSNP:769805151
3780 3780 c, t dbSNP:773406106
3800 3800 -, caaa dbSNP:559255193
3800 3800 a, c dbSNP:1894417
3811 3811 a, g dbSNP:766992148
3839 3839 c, t dbSNP:189815560
3852 3852 c, g dbSNP:773135056
3877 3877 c, t dbSNP:759647942
3911 3911 a, g dbSNP:759926909
3915 3915 c, t dbSNP:772094808
3920 3920 a, g dbSNP:141005414
3952 3952 a, c dbSNP:1894418
3963 3963 a, g dbSNP:138745617
4093 4093 a, g dbSNP:752248178
4112 4112 c, g dbSNP:760339525
4124 4124 g, t dbSNP:149429660
4168 4168 a, g dbSNP:718302
4177 4177 a, c dbSNP:377429675
4229 4229 c, t dbSNP:147114489
4230 4230 a, g dbSNP:750920468
4244 4244 a, g dbSNP:758003630
4257 4257 a, t dbSNP:138443284
4300 4300 a, c dbSNP:751295282
4306 4306 a, c dbSNP:763558376
4335 4335 a, g dbSNP:144006455
4385 4385 -, cctc dbSNP:773840982
4417 4417 c, t dbSNP:186570524
4512 4512 a, c dbSNP:769591275
4628 4628 a, g dbSNP:147159870
4667 4667 a, g dbSNP:148632928
4677 4677 g, t dbSNP:141223944
4717 4717 c, t dbSNP:775541115
4737 4737 a, c dbSNP:150716965
4784 4784 -, a dbSNP:779634495
4788 4788 c, t dbSNP:768770074
4789 4789 a, g dbSNP:776842545
4790 4790 c, t dbSNP:139065358
4791 4791 c, t dbSNP:778752986
4800 4800 a, g dbSNP:144125698
4825 4825 a, t dbSNP:750231550
4854 4854 c, g dbSNP:751015608
4919 4919 c, t dbSNP:763520621
4937 4937 c, t dbSNP:146520078
4939 4939 c, t dbSNP:533345329
4962 4962 g, t dbSNP:57128317

Target ORF information:

RefSeq Version XM_011545534
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens phosphate regulating endopeptidase homolog, X-linked (PHEX), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011545534

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGTGGATA CTGCCGTGCT TTTAGGAGCT AACAGTTCCA GAGCAGAGCA TGACATGAAG 
TCAGTGCTCA GATTGGAAAT TAAGATAGCT GAGATAATGA TTCCACATGA AAACCGAACC
AGCGAGGCCA TGTACAACAA AATGAACATT TCTGAACTGA GTGCTATGAT TCCCCAGTTC
GACTGGCTGG GCTACATCAA GAAGGTCATT GACACCAGAC TCTACCCCCA TCTGAAAGAC
ATCAGCCCCT CCGAGAATGT GGTGGTCCGC GTCCCGCAGT ACTTTAAAGA TTTGTTTAGG
ATATTAGGGT CTGAGAGAAA GAAGACCATT GCCAACTATT TGGTGTGGAG AATGGTTTAT
TCCAGAATTC CAAACCTTAG CAGGCGCTTT CAGTATAGAT GGCTGGAATT CTCAAGGGTA
ATCCAGGGGA CCACAACTTT GCTGCCTCAA TGGGACAAAT GTGTAAACTT TATTGAAAGT
GCCCTCCCTT ATGTTGTTGG AAAGATGTTT GTAGATGTGT ACTTCCAGGA AGATAAGAAG
GAAATGATGG AGGAATTGGT TGAGGGCGTT CGCTGGGCCT TTATTGACAT GCTAGAGAAA
GAAAATGAGT GGATGGATGC AGGAACGAAA AGGAAAGCCA AAGAAAAGGC GAGAGCTGTT
TTGGCAAAAG TTGGCTATCC AGAGTTTATA ATGAATGATA CTCATGTTAA TGAAGACCTC
AAAGCTATCA AGTTTTCAGA AGCCGACTAC TTTGGCAACG TCCTACAAAC TCGCAAGTAT
TTAGCACAGT CTGATTTCTT CTGGCTAAGA AAAGCCGTTC CAAAAACAGA GTGGTTTACA
AATCCGACGA CTGTCAATGC CTTCTACAGT GCATCCACCA ACCAGATCCG ATTTCCAGCA
GGAGAGCTCC AGAAGCCTTT CTTTTGGGGA ACAGAATATC CTCGATCTCT GAGTTATGGT
GCTATAGGAG TAATTGTCGG ACATGAATTT ACACATGGAT TTGATAATAA TGGTAGAAAA
TATGATAAAA ATGGAAACCT GGATCCTTGG TGGTCTACTG AATCAGAAGA AAAGTTTAAG
GAAAAAACAA AATGCATGAT TAACCAGTAT AGCAACTATT ATTGGAAGAA AGCTGGCTTA
AATGTCAAGG GGAAGAGGAC CCTGGGAGAA AATATTGCTG ATAATGGAGG CCTGCGGGAA
GCTTTTAGGG CTTACAGGAA ATGGATAAAT GACAGAAGGC AGGGACTTGA GGAGCCTCTT
CTACCAGGCA TCACATTCAC CAACAACCAG CTCTTCTTCC TGAGTTATGC TCATGTGAGG
TGCAATTCCT ACAGACCAGA AGCTGCCCGA GAACAAGTCC AAATTGGTGC TCACAGTCCC
CCTCAGTTTA GGGTCAATGG TGCAATTAGT AACTTTGAAG AATTCCAGAA AGCTTTTAAC
TGTCCACCCA ATTCCACGAT GAACAGAGGC ATGGACTCCT GCCGACTCTG GTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu59659
Accession Version XM_011545535.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1428bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product phosphate-regulating neutral endopeptidase isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167197.2) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGAAGCAG AAACAGGGAG CAGCGTGGAG ACTGGAAAGA AGGCCAACAG AGGCACTCGA 
ATTGCCCTGG TCGTGTTTGT CGGTGGCACC CTAGTTCTGG GCACGATCCT CTTTCTAGTG
AGTCAAGGTC TCTTAAGTCT CCAAGCTAAA CAGGAGTACT GCCTGAAGCC AGAATGCATC
GAAGCGGCTG CTGCCATCTT AAGTAAAGTA AATCTGTCTG TGGATCCTTG TGATAATTTC
TTCCGGTTCG CTTGTGATGG CTGGATAAGC AATAATCCAA TTCCCGAAGA TATGCCAAGC
TATGGGGTTT ATCCTTGGCT GAGACATAAT GTTGACCTCA AGTTGAAGGA ACTTTTGGAG
AAATCAATCA GTAGAAGGCG GGACACCGAA GCCATACAGA AAGCCAAAAT CCTTTATTCA
TCCTGCATGA ATGAGAAAGC GATTGAAAAA GCAGATGCCA AGCCACTGCT ACACATCCTA
CGGCATTCAC CTTTCCGCTG GCCCGTGCTT GAATCTAATA TTGGCCCTGA AGGGGTTTGG
TCAGAGAGAA AGTTCAGCCT TCTGCAGACA CTTGCAACGT TTCGTGGTCA ATACAGCAAT
TCTGTGTTCA TCCGTTTGTA TGTGTCCCCT GATGACAAAG CATCCAATGA ACATATCTTG
AAGCTGGACC AAGCAACACT CTCCCTGGCC GTGAGGGAAG ACTACCTTGA TAACAGTACA
GAAGCCAAGT CTTATCGGGA TGCCCTTTAC AAGTTCATGG TGGATACTGC CGTGCTTTTA
GGAGCTAACA GTTCCAGAGC AGAGCATGAC ATGAAGTCAG TGCTCAGATT GGAAATTAAG
ATAGCTGAGA TAATGATTCC ACATGAAAAC CGAACCAGCG AGGCCATGTA CAACAAAATG
AACATTTCTG AACTGAGTGC TATGATTCCC CAGTTCGACT GGCTGGGCTA CATCAAGAAG
GTCATTGACA CCAGACTCTA CCCCCATCTG AAAGACATCA GCCCCTCCGA GAATGTGGTG
GTCCGCGTCC CGCAGTACTT TAAAGATTTG TTTAGGATAT TAGGGTCTGA GAGAAAGAAG
ACCATTGCCA ACTATTTGGT GTGGAGAATG GTTTATTCCA GAATTCCAAA CCTTAGCAGG
CGCTTTCAGT ATAGATGGCT GGAATTCTCA AGGGTAATCC AGGGGACCAC AACTTTGCTG
CCTCAATGGG ACAAATGTGT AAACTTTATT GAAAGTGCCC TCCCTTATGT TGTTGGAAAG
ATGTTTGTAG ATGTGTACTT CCAGGAAGAT AAGAAGGAAA TGATGGAGGA ATTGGTTGAG
GGCGTTCGCT GGGCCTTTAT TGACATGCTA GAGAAAGAAA ATGAGTGGAT GGATGCAGGA
ACGAAAAGGA AAGCCAAAGA AAAGGTGGGT CCCCTGAGTG AGTACTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011543837.1
CDS680..2107
Misc Feature(1)899..>2086(+)
Translation
Position Chain Variation Link
137 137 a, g dbSNP:190284199
189 189 g, t dbSNP:182865352
220 220 c, t dbSNP:764250164
244 244 a, g dbSNP:555241989
267 267 a, g dbSNP:776891320
271 271 a, t dbSNP:573757656
286 286 a, c dbSNP:187601331
302 302 g, t dbSNP:178709
363 363 a, g dbSNP:371226416
370 370 c, t dbSNP:758949471
426 426 a, g dbSNP:770448887
472 472 a, g dbSNP:780387907
478 478 c, g dbSNP:777384160
534 534 a, g dbSNP:192414303
554 554 c, g dbSNP:185830047
559 559 -, g dbSNP:35301418
572 572 a, g dbSNP:149541983
590 590 a, g dbSNP:178710
642 642 a, c dbSNP:752602189
643 643 g, t dbSNP:201391816
647 647 c, t dbSNP:5951494
648 648 c, t dbSNP:750612939
657 657 a, g dbSNP:758504261
659 659 a, g dbSNP:780051359
662 662 c, t dbSNP:201251651
663 663 c, t dbSNP:755577853
669 669 c, t dbSNP:781538001
689 689 c, g dbSNP:147859619
697 697 c, g dbSNP:770026330
723 723 c, g dbSNP:773033853
726 726 a, g dbSNP:770920860
737 737 c, g dbSNP:770573978
738 738 -, a dbSNP:34610947
743 743 g, t dbSNP:773927462
752 752 a, g dbSNP:759110019
757 757 g, t dbSNP:767546324
760 760 c, t dbSNP:139862893
761 761 a, g dbSNP:760556268
783 783 c, t dbSNP:539005958
784 784 a, g dbSNP:763757285
810 810 a, t dbSNP:775529233
811 811 c, g dbSNP:778468346
821 821 c, g dbSNP:202074612
826 826 c, t dbSNP:768503558
835 835 a, g dbSNP:776477320
858 858 g, t dbSNP:756452995
860 860 a, g dbSNP:770630990
864 864 c, t dbSNP:145393882
865 865 a, g dbSNP:751752229
875 875 a, g dbSNP:779373231
888 888 c, g, t dbSNP:754929336
893 893 c, t dbSNP:768639876
905 905 c, g dbSNP:201394441
914 914 a, g dbSNP:761638747
924 924 a, g, t dbSNP:769541316
928 928 c, t dbSNP:145224279
929 929 a, g dbSNP:767642869
933 933 a, g dbSNP:137853269
936 936 a, g dbSNP:752781848
950 950 a, c dbSNP:375707069
959 959 a, g dbSNP:764744535
965 965 a, g dbSNP:149168023
967 967 a, g dbSNP:112836831
978 978 a, g dbSNP:765647670
981 981 a, g dbSNP:750103659
986 986 a, g dbSNP:758053428
997 997 a, g dbSNP:193922458
1003 1003 a, g dbSNP:779745439
1021 1021 a, g dbSNP:746551939
1031 1031 c, t dbSNP:772238348
1046 1046 a, g dbSNP:775756294
1058 1058 c, t dbSNP:375376231
1059 1059 a, g dbSNP:370698419
1066 1066 c, t dbSNP:777298207
1072 1072 c, t dbSNP:762351671
1076 1076 c, g dbSNP:151306376
1098 1098 c, t dbSNP:140678356
1119 1119 c, t dbSNP:749081778
1120 1120 a, g dbSNP:770726332
1122 1122 c, t dbSNP:775603606
1123 1123 c, t dbSNP:145881500
1129 1129 a, g dbSNP:768868675
1156 1156 c, t dbSNP:776784616
1159 1159 a, g dbSNP:761971488
1160 1160 c, t dbSNP:765714025
1161 1161 a, g dbSNP:138497409
1168 1168 a, g dbSNP:140231382
1170 1170 c, g dbSNP:766719010
1175 1175 c, t dbSNP:751230094
1176 1176 a, g dbSNP:150297950
1183 1183 c, t dbSNP:767157065
1184 1184 a, g dbSNP:187824835
1187 1187 c, g dbSNP:755595286
1197 1197 a, g dbSNP:777607846
1204 1204 a, c dbSNP:753767214
1216 1216 a, t dbSNP:137961493
1220 1220 g, t dbSNP:778710788
1246 1246 c, g dbSNP:747237564
1257 1257 c, t dbSNP:769066725
1258 1258 a, g dbSNP:781542537
1263 1263 a, g dbSNP:748279755
1292 1292 c, t dbSNP:769878509
1297 1297 g, t dbSNP:773617103
1299 1299 a, g dbSNP:763461759
1300 1300 c, t dbSNP:771208171
1304 1304 -, c dbSNP:36117823
1305 1305 c, g, t dbSNP:774768015
1310 1310 a, g dbSNP:370610267
1312 1312 c, t dbSNP:372618065
1332 1332 a, g dbSNP:774907553
1352 1352 a, g dbSNP:749327791
1357 1357 a, g dbSNP:771529993
1369 1369 c, g, t dbSNP:149487757
1370 1370 a, g dbSNP:376291775
1389 1389 a, t dbSNP:775148284
1403 1403 a, g dbSNP:760319054
1404 1404 c, g dbSNP:144007621
1409 1409 c, t dbSNP:763517570
1419 1419 a, g dbSNP:779431331
1434 1434 c, t dbSNP:267606945
1438 1438 a, g dbSNP:267606946
1446 1446 c, g dbSNP:746328622
1448 1448 c, g dbSNP:772441926
1450 1450 c, t dbSNP:142833404
1461 1461 a, g dbSNP:113219043
1476 1476 a, g dbSNP:775766235
1499 1499 a, g dbSNP:747331129
1500 1500 c, t dbSNP:768413746
1506 1506 a, g dbSNP:776124957
1508 1508 c, t dbSNP:761416628
1509 1509 a, t dbSNP:137853268
1519 1519 a, g dbSNP:147430384
1528 1528 a, g dbSNP:773293894
1539 1539 c, t dbSNP:746436151
1546 1546 a, g dbSNP:139771307
1554 1554 c, t dbSNP:768862054
1555 1555 a, c dbSNP:776367122
1558 1558 c, t dbSNP:772573976
1559 1559 a, g dbSNP:747696209
1563 1563 c, g dbSNP:769430757
1564 1564 -, cc dbSNP:193922460
1574 1574 a, g dbSNP:772921325
1578 1578 c, t dbSNP:762535711
1580 1580 a, c dbSNP:199893153
1582 1582 c, t dbSNP:142755818
1583 1583 a, g dbSNP:759411768
1587 1587 a, c dbSNP:767171186
1589 1589 a, g dbSNP:754106853
1597 1597 c, t dbSNP:150619847
1601 1601 a, g dbSNP:372663150
1615 1615 c, t dbSNP:760451270
1616 1616 a, g dbSNP:757539874
1624 1624 g, t dbSNP:750613071
1626 1626 g, t dbSNP:763042990
1627 1627 c, g dbSNP:766310950
1636 1636 a, g, t dbSNP:373261521
1650 1650 c, t dbSNP:199965602
1652 1652 a, c dbSNP:781713539
1661 1661 c, g dbSNP:201383931
1668 1668 g, t dbSNP:756512186
1675 1675 c, t dbSNP:139749399
1687 1687 c, t dbSNP:775973349
1688 1688 a, g dbSNP:770491624
1693 1693 c, t dbSNP:149793221
1700 1700 g, t dbSNP:745382329
1703 1703 c, t dbSNP:761575825
1704 1704 a, g dbSNP:376461141
1705 1705 c, t dbSNP:746847960
1706 1706 a, g dbSNP:768400503
1721 1721 a, g dbSNP:773436322
1724 1724 c, g dbSNP:763094620
1741 1741 a, g dbSNP:766616716
1756 1756 a, g dbSNP:774349246
1758 1758 a, g dbSNP:185862803
1762 1762 a, c dbSNP:753547432
1772 1772 c, t dbSNP:756929627
1790 1790 a, g dbSNP:759015845
1797 1797 c, t dbSNP:778616699
1798 1798 c, t dbSNP:753296824
1819 1819 a, g dbSNP:757894404
1828 1828 a, g dbSNP:779998335
1833 1833 a, g dbSNP:373233283
1841 1841 a, g dbSNP:746890776
1861 1861 a, g dbSNP:774598902
1864 1864 c, g dbSNP:371115510
1875 1875 c, t dbSNP:767652424
1881 1881 c, t dbSNP:145778165
1885 1885 a, g dbSNP:151234075
1899 1899 c, t dbSNP:764695823
1904 1904 c, t dbSNP:754314481
1927 1927 c, t dbSNP:757620472
1940 1940 a, g dbSNP:764839343
1946 1946 a, g dbSNP:750052547
1957 1957 c, t dbSNP:375729152
1963 1963 g, t dbSNP:757869310
2002 2002 c, t dbSNP:769336836
2003 2003 a, g dbSNP:777167473
2023 2023 c, t dbSNP:144911719
2038 2038 a, c dbSNP:202164519
2053 2053 c, t dbSNP:370746437
2059 2059 a, g dbSNP:750047503
2061 2061 c, t dbSNP:374873766
2062 2062 a, g dbSNP:77710864
2074 2074 c, g dbSNP:751117913
2083 2083 c, g dbSNP:754449807
2086 2086 a, g dbSNP:771565434
2162 2162 a, g dbSNP:746164856
2188 2188 c, t dbSNP:772167036
2213 2213 c, t dbSNP:376369335

Target ORF information:

RefSeq Version XM_011545535
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens phosphate regulating endopeptidase homolog, X-linked (PHEX), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011545535

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGAAGCAG AAACAGGGAG CAGCGTGGAG ACTGGAAAGA AGGCCAACAG AGGCACTCGA 
ATTGCCCTGG TCGTGTTTGT CGGTGGCACC CTAGTTCTGG GCACGATCCT CTTTCTAGTG
AGTCAAGGTC TCTTAAGTCT CCAAGCTAAA CAGGAGTACT GCCTGAAGCC AGAATGCATC
GAAGCGGCTG CTGCCATCTT AAGTAAAGTA AATCTGTCTG TGGATCCTTG TGATAATTTC
TTCCGGTTCG CTTGTGATGG CTGGATAAGC AATAATCCAA TTCCCGAAGA TATGCCAAGC
TATGGGGTTT ATCCTTGGCT GAGACATAAT GTTGACCTCA AGTTGAAGGA ACTTTTGGAG
AAATCAATCA GTAGAAGGCG GGACACCGAA GCCATACAGA AAGCCAAAAT CCTTTATTCA
TCCTGCATGA ATGAGAAAGC GATTGAAAAA GCAGATGCCA AGCCACTGCT ACACATCCTA
CGGCATTCAC CTTTCCGCTG GCCCGTGCTT GAATCTAATA TTGGCCCTGA AGGGGTTTGG
TCAGAGAGAA AGTTCAGCCT TCTGCAGACA CTTGCAACGT TTCGTGGTCA ATACAGCAAT
TCTGTGTTCA TCCGTTTGTA TGTGTCCCCT GATGACAAAG CATCCAATGA ACATATCTTG
AAGCTGGACC AAGCAACACT CTCCCTGGCC GTGAGGGAAG ACTACCTTGA TAACAGTACA
GAAGCCAAGT CTTATCGGGA TGCCCTTTAC AAGTTCATGG TGGATACTGC CGTGCTTTTA
GGAGCTAACA GTTCCAGAGC AGAGCATGAC ATGAAGTCAG TGCTCAGATT GGAAATTAAG
ATAGCTGAGA TAATGATTCC ACATGAAAAC CGAACCAGCG AGGCCATGTA CAACAAAATG
AACATTTCTG AACTGAGTGC TATGATTCCC CAGTTCGACT GGCTGGGCTA CATCAAGAAG
GTCATTGACA CCAGACTCTA CCCCCATCTG AAAGACATCA GCCCCTCCGA GAATGTGGTG
GTCCGCGTCC CGCAGTACTT TAAAGATTTG TTTAGGATAT TAGGGTCTGA GAGAAAGAAG
ACCATTGCCA ACTATTTGGT GTGGAGAATG GTTTATTCCA GAATTCCAAA CCTTAGCAGG
CGCTTTCAGT ATAGATGGCT GGAATTCTCA AGGGTAATCC AGGGGACCAC AACTTTGCTG
CCTCAATGGG ACAAATGTGT AAACTTTATT GAAAGTGCCC TCCCTTATGT TGTTGGAAAG
ATGTTTGTAG ATGTGTACTT CCAGGAAGAT AAGAAGGAAA TGATGGAGGA ATTGGTTGAG
GGCGTTCGCT GGGCCTTTAT TGACATGCTA GAGAAAGAAA ATGAGTGGAT GGATGCAGGA
ACGAAAAGGA AAGCCAAAGA AAAGGTGGGT CCCCTGAGTG AGTACTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu59660
Accession Version XM_011545536.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1143bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product phosphate-regulating neutral endopeptidase isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167197.2) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGGTTTATT CCAGAATTCC AAACCTTAGC AGGCGCTTTC AGTATAGATG GCTGGAATTC 
TCAAGGGTAA TCCAGGGGAC CACAACTTTG CTGCCTCAAT GGGACAAATG TGTAAACTTT
ATTGAAAGTG CCCTCCCTTA TGTTGTTGGA AAGATGTTTG TAGATGTGTA CTTCCAGGAA
GATAAGAAGG AAATGATGGA GGAATTGGTT GAGGGCGTTC GCTGGGCCTT TATTGACATG
CTAGAGAAAG AAAATGAGTG GATGGATGCA GGAACGAAAA GGAAAGCCAA AGAAAAGGCG
AGAGCTGTTT TGGCAAAAGT TGGCTATCCA GAGTTTATAA TGAATGATAC TCATGTTAAT
GAAGACCTCA AAGCTATCAA GTTTTCAGAA GCCGACTACT TTGGCAACGT CCTACAAACT
CGCAAGTATT TAGCACAGTC TGATTTCTTC TGGCTAAGAA AAGCCGTTCC AAAAACAGAG
TGGTTTACAA ATCCGACGAC TGTCAATGCC TTCTACAGTG CATCCACCAA CCAGATCCGA
TTTCCAGCAG GAGAGCTCCA GAAGCCTTTC TTTTGGGGAA CAGAATATCC TCGATCTCTG
AGTTATGGTG CTATAGGAGT AATTGTCGGA CATGAATTTA CACATGGATT TGATAATAAT
GGTAGAAAAT ATGATAAAAA TGGAAACCTG GATCCTTGGT GGTCTACTGA ATCAGAAGAA
AAGTTTAAGG AAAAAACAAA ATGCATGATT AACCAGTATA GCAACTATTA TTGGAAGAAA
GCTGGCTTAA ATGTCAAGGG GAAGAGGACC CTGGGAGAAA ATATTGCTGA TAATGGAGGC
CTGCGGGAAG CTTTTAGGGC TTACAGGAAA TGGATAAATG ACAGAAGGCA GGGACTTGAG
GAGCCTCTTC TACCAGGCAT CACATTCACC AACAACCAGC TCTTCTTCCT GAGTTATGCT
CATGTGAGGT GCAATTCCTA CAGACCAGAA GCTGCCCGAG AACAAGTCCA AATTGGTGCT
CACAGTCCCC CTCAGTTTAG GGTCAATGGT GCAATTAGTA ACTTTGAAGA ATTCCAGAAA
GCTTTTAACT GTCCACCCAA TTCCACGATG AACAGAGGCA TGGACTCCTG CCGACTCTGG
TAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011543838.1
CDS130..1272
Misc Feature(1)130..1263(+)
Misc Feature(2)634..1170(+)
Misc Feature(3)760..948(+)
Translation
Position Chain Variation Link
12 12 c, t dbSNP:762168059
13 13 a, g dbSNP:141787046
18 18 c, g dbSNP:2285063
30 30 -, ttg dbSNP:201418442
44 44 -, gtt dbSNP:367942178
49 49 c, g dbSNP:766028367
105 105 a, c dbSNP:753547432
115 115 c, t dbSNP:756929627
133 133 a, g dbSNP:759015845
140 140 c, t dbSNP:778616699
141 141 c, t dbSNP:753296824
162 162 a, g dbSNP:757894404
171 171 a, g dbSNP:779998335
176 176 a, g dbSNP:373233283
184 184 a, g dbSNP:746890776
204 204 a, g dbSNP:774598902
207 207 c, g dbSNP:371115510
218 218 c, t dbSNP:767652424
224 224 c, t dbSNP:145778165
228 228 a, g dbSNP:151234075
242 242 c, t dbSNP:764695823
247 247 c, t dbSNP:754314481
270 270 c, t dbSNP:757620472
283 283 a, g dbSNP:764839343
289 289 a, g dbSNP:750052547
300 300 c, t dbSNP:375729152
306 306 g, t dbSNP:757869310
345 345 c, t dbSNP:769336836
346 346 a, g dbSNP:777167473
366 366 c, t dbSNP:144911719
381 381 a, c dbSNP:202164519
396 396 c, t dbSNP:370746437
402 402 a, g dbSNP:750047503
404 404 c, t dbSNP:374873766
405 405 a, g dbSNP:77710864
417 417 c, g dbSNP:751117913
426 426 c, g dbSNP:754449807
428 428 c, t dbSNP:375593493
448 448 a, g dbSNP:766990714
459 459 a, g dbSNP:141436752
468 468 a, g dbSNP:756146878
478 478 a, g dbSNP:777560709
483 483 c, t dbSNP:765101791
485 485 a, t dbSNP:369896990
492 492 a, t dbSNP:371934258
503 503 a, c dbSNP:747180101
520 520 a, g dbSNP:765067632
521 521 a, c dbSNP:751837244
523 523 a, g dbSNP:373235530
524 524 a, g dbSNP:755284765
537 537 c, t dbSNP:764771688
538 538 a, g dbSNP:781248973
543 543 a, c dbSNP:748298612
553 553 a, c dbSNP:753522380
554 554 a, c dbSNP:778363445
567 567 c, g dbSNP:201266084
576 576 a, c dbSNP:749734873
611 611 a, g dbSNP:193922455
617 617 c, t dbSNP:767812044
638 638 c, t dbSNP:199935279
648 648 c, t dbSNP:752810184
677 677 c, t dbSNP:773244112
678 678 a, g dbSNP:143427381
686 686 c, t dbSNP:137853270
697 697 c, t dbSNP:762828809
702 702 c, t dbSNP:766026766
721 721 a, c, t dbSNP:137853271
722 722 a, g dbSNP:760870713
724 724 a, t dbSNP:768470624
726 726 c, t dbSNP:112728394
744 744 a, g dbSNP:780959710
748 748 a, g dbSNP:747692520
756 756 c, t dbSNP:769379550
765 765 a, g dbSNP:773291977
770 770 c, t dbSNP:762728667
785 785 a, t dbSNP:772130004
795 795 a, g dbSNP:781013156
816 816 c, t dbSNP:747743987
831 831 g, t dbSNP:755686699
840 840 a, g dbSNP:146055519
841 841 a, t dbSNP:748815816
888 888 c, t dbSNP:375441152
938 938 a, c dbSNP:111636676
939 939 a, c dbSNP:201343697
940 940 a, c dbSNP:756017274
963 963 c, t dbSNP:755885733
971 971 c, t dbSNP:193922456
972 972 a, g dbSNP:777456871
974 974 a, g dbSNP:748792378
984 984 c, t dbSNP:756752961
1003 1003 a, g dbSNP:774626712
1021 1021 g, t dbSNP:193922457
1034 1034 a, c dbSNP:759663012
1043 1043 a, c, t dbSNP:199517401
1047 1047 a, c dbSNP:760972913
1051 1051 a, c, g dbSNP:112577880
1052 1052 c, g dbSNP:764465237
1059 1059 c, t dbSNP:766459849
1074 1074 c, g dbSNP:373674171
1078 1078 a, c dbSNP:764784243
1090 1090 a, c dbSNP:200733697
1123 1123 g, t dbSNP:746918835
1130 1130 a, t dbSNP:747487296
1163 1163 a, g dbSNP:769039646
1173 1173 c, g dbSNP:772854418
1175 1175 a, c, g dbSNP:191028600
1183 1183 a, g dbSNP:766003166
1185 1185 c, g, t dbSNP:372307955
1195 1195 a, g dbSNP:767518128
1210 1210 g, t dbSNP:752729907
1218 1218 a, c dbSNP:376952568
1227 1227 c, t dbSNP:755989604
1229 1229 a, g dbSNP:367955819
1235 1235 c, t dbSNP:371825581
1236 1236 a, g dbSNP:140742016
1257 1257 c, g dbSNP:150112217
1262 1262 a, g dbSNP:138773278
1266 1266 c, g dbSNP:747154530
1273 1273 a, c dbSNP:754974866
1280 1280 a, g dbSNP:781727969
1291 1291 a, g dbSNP:374774539
1297 1297 c, t dbSNP:770279983
1319 1319 c, t dbSNP:370155243
1320 1320 a, g dbSNP:765479131
1330 1330 c, t dbSNP:183223600
1343 1343 a, g dbSNP:186466573
1382 1382 a, t dbSNP:780324969
1439 1439 a, g dbSNP:751689587
1479 1479 a, g dbSNP:755389049
1490 1490 a, c dbSNP:141594056
1494 1494 c, t dbSNP:748724335
1497 1497 a, g dbSNP:770275990
1499 1499 c, g dbSNP:765787001
1554 1554 g, t dbSNP:373526963
1577 1577 a, g dbSNP:189715720
1599 1599 c, g dbSNP:748836233
1607 1607 a, g dbSNP:770308822
1611 1611 a, g dbSNP:773553690
1633 1633 c, t dbSNP:182654518
1660 1660 a, g dbSNP:759086924
1697 1697 a, g dbSNP:775420101
1728 1728 a, g dbSNP:147507544
1744 1744 g, t dbSNP:763522632
1752 1752 c, t dbSNP:766900352
1800 1800 a, g dbSNP:113813269
1846 1846 c, g dbSNP:776361459
1863 1863 a, g dbSNP:369147272
1943 1943 g, t dbSNP:751959768
1960 1960 -, tgag dbSNP:750660265
1971 1971 c, g dbSNP:145080586
1977 1977 -, a dbSNP:766317343
2040 2040 c, t dbSNP:754747451
2049 2049 a, c dbSNP:188175876
2092 2092 a, g dbSNP:5951739
2095 2095 a, g dbSNP:41309575
2120 2120 -, t dbSNP:753078908
2144 2144 c, g, t dbSNP:376254574
2145 2145 a, g dbSNP:149673099
2167 2167 a, g dbSNP:749711087
2170 2170 c, t dbSNP:145476860
2192 2192 a, c dbSNP:192770679
2204 2204 a, g dbSNP:183619109
2220 2220 c, t dbSNP:187522891
2250 2250 -, t dbSNP:200473244
2252 2252 a, tagtgcaaag dbSNP:386824235
2252 2252 -, tagtgcaaa dbSNP:200544019
2252 2252 -, tagtgcaa dbSNP:79379908
2254 2254 -, gtgcaaag dbSNP:199638664
2255 2255 a, t dbSNP:777794098
2256 2256 a, g dbSNP:749259065
2259 2259 -, aag dbSNP:746800228
2261 2261 a, g dbSNP:200248764
2387 2387 a, g dbSNP:192098973
2393 2393 a, c dbSNP:757161203
2419 2419 a, g dbSNP:148478140
2427 2427 c, t dbSNP:761631760
2496 2496 c, t dbSNP:369535826
2527 2527 -, gtgtgtgtgtgtggtgtgtgtgt dbSNP:766550946
2528 2528 -, gtgtgtgtgt dbSNP:771619032
2528 2528 -, gt dbSNP:749752907
2559 2559 -, gtgtgtgtgt dbSNP:59496974
2577 2577 g, t dbSNP:774285492
2602 2602 c, t dbSNP:16981889
2680 2680 c, t dbSNP:184539861
2750 2750 a, t dbSNP:752876880
2761 2761 a, t dbSNP:377467619
2762 2762 -, a dbSNP:540966419
2774 2774 -, aat dbSNP:762309910
2775 2775 -, a, at dbSNP:71879575
2776 2776 a, t dbSNP:59285690
2776 2776 -, t dbSNP:372076236
2778 2778 a, t dbSNP:59180400
2778 2778 -, t dbSNP:370627436
2813 2813 a, c dbSNP:764345252
2816 2816 c, t dbSNP:5951740
2839 2839 g, t dbSNP:753777813
2923 2923 c, t dbSNP:757697615
2933 2933 c, t dbSNP:5951741
2954 2954 a, t dbSNP:5951742
3020 3020 c, g dbSNP:191203770
3033 3033 c, g dbSNP:745656887
3057 3057 a, g dbSNP:145670027
3060 3060 g, t dbSNP:768926927
3151 3151 c, g dbSNP:184499919
3232 3232 a, g dbSNP:748292420
3263 3263 a, g dbSNP:373843573
3283 3283 -, tcac dbSNP:776288532
3291 3291 c, t dbSNP:769805151
3402 3402 c, t dbSNP:773406106
3422 3422 -, caaa dbSNP:559255193
3422 3422 a, c dbSNP:1894417
3433 3433 a, g dbSNP:766992148
3461 3461 c, t dbSNP:189815560
3474 3474 c, g dbSNP:773135056
3499 3499 c, t dbSNP:759647942
3533 3533 a, g dbSNP:759926909
3537 3537 c, t dbSNP:772094808
3542 3542 a, g dbSNP:141005414
3574 3574 a, c dbSNP:1894418
3585 3585 a, g dbSNP:138745617
3715 3715 a, g dbSNP:752248178
3734 3734 c, g dbSNP:760339525
3746 3746 g, t dbSNP:149429660
3790 3790 a, g dbSNP:718302
3799 3799 a, c dbSNP:377429675
3851 3851 c, t dbSNP:147114489
3852 3852 a, g dbSNP:750920468
3866 3866 a, g dbSNP:758003630
3879 3879 a, t dbSNP:138443284
3922 3922 a, c dbSNP:751295282
3928 3928 a, c dbSNP:763558376
3957 3957 a, g dbSNP:144006455
4007 4007 -, cctc dbSNP:773840982
4039 4039 c, t dbSNP:186570524
4134 4134 a, c dbSNP:769591275
4250 4250 a, g dbSNP:147159870
4289 4289 a, g dbSNP:148632928
4299 4299 g, t dbSNP:141223944
4339 4339 c, t dbSNP:775541115
4359 4359 a, c dbSNP:150716965
4406 4406 -, a dbSNP:779634495
4410 4410 c, t dbSNP:768770074
4411 4411 a, g dbSNP:776842545
4412 4412 c, t dbSNP:139065358
4413 4413 c, t dbSNP:778752986
4422 4422 a, g dbSNP:144125698
4447 4447 a, t dbSNP:750231550
4476 4476 c, g dbSNP:751015608
4541 4541 c, t dbSNP:763520621
4559 4559 c, t dbSNP:146520078
4561 4561 c, t dbSNP:533345329
4584 4584 g, t dbSNP:57128317

Target ORF information:

RefSeq Version XM_011545536
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens phosphate regulating endopeptidase homolog, X-linked (PHEX), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011545536

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGGTTTATT CCAGAATTCC AAACCTTAGC AGGCGCTTTC AGTATAGATG GCTGGAATTC 
TCAAGGGTAA TCCAGGGGAC CACAACTTTG CTGCCTCAAT GGGACAAATG TGTAAACTTT
ATTGAAAGTG CCCTCCCTTA TGTTGTTGGA AAGATGTTTG TAGATGTGTA CTTCCAGGAA
GATAAGAAGG AAATGATGGA GGAATTGGTT GAGGGCGTTC GCTGGGCCTT TATTGACATG
CTAGAGAAAG AAAATGAGTG GATGGATGCA GGAACGAAAA GGAAAGCCAA AGAAAAGGCG
AGAGCTGTTT TGGCAAAAGT TGGCTATCCA GAGTTTATAA TGAATGATAC TCATGTTAAT
GAAGACCTCA AAGCTATCAA GTTTTCAGAA GCCGACTACT TTGGCAACGT CCTACAAACT
CGCAAGTATT TAGCACAGTC TGATTTCTTC TGGCTAAGAA AAGCCGTTCC AAAAACAGAG
TGGTTTACAA ATCCGACGAC TGTCAATGCC TTCTACAGTG CATCCACCAA CCAGATCCGA
TTTCCAGCAG GAGAGCTCCA GAAGCCTTTC TTTTGGGGAA CAGAATATCC TCGATCTCTG
AGTTATGGTG CTATAGGAGT AATTGTCGGA CATGAATTTA CACATGGATT TGATAATAAT
GGTAGAAAAT ATGATAAAAA TGGAAACCTG GATCCTTGGT GGTCTACTGA ATCAGAAGAA
AAGTTTAAGG AAAAAACAAA ATGCATGATT AACCAGTATA GCAACTATTA TTGGAAGAAA
GCTGGCTTAA ATGTCAAGGG GAAGAGGACC CTGGGAGAAA ATATTGCTGA TAATGGAGGC
CTGCGGGAAG CTTTTAGGGC TTACAGGAAA TGGATAAATG ACAGAAGGCA GGGACTTGAG
GAGCCTCTTC TACCAGGCAT CACATTCACC AACAACCAGC TCTTCTTCCT GAGTTATGCT
CATGTGAGGT GCAATTCCTA CAGACCAGAA GCTGCCCGAG AACAAGTCCA AATTGGTGCT
CACAGTCCCC CTCAGTTTAG GGTCAATGGT GCAATTAGTA ACTTTGAAGA ATTCCAGAAA
GCTTTTAACT GTCCACCCAA TTCCACGATG AACAGAGGCA TGGACTCCTG CCGACTCTGG
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu21896
Accession Version NM_000444.5 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2250bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product phosphate-regulating neutral endopeptidase isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U82970.1, Y10196.1 and AK301528.1. This sequence is a reference standard in the RefSeqGene project. On Sep 19, 2013 this sequence version replaced gi:181336426. Summary: The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U82970.1, U75645.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2144333 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGGAAGCAG AAACAGGGAG CAGCGTGGAG ACTGGAAAGA AGGCCAACAG AGGCACTCGA 
ATTGCCCTGG TCGTGTTTGT CGGTGGCACC CTAGTTCTGG GCACGATCCT CTTTCTAGTG
AGTCAAGGTC TCTTAAGTCT CCAAGCTAAA CAGGAGTACT GCCTGAAGCC AGAATGCATC
GAAGCGGCTG CTGCCATCTT AAGTAAAGTA AATCTGTCTG TGGATCCTTG TGATAATTTC
TTCCGGTTCG CTTGTGATGG CTGGATAAGC AATAATCCAA TTCCCGAAGA TATGCCAAGC
TATGGGGTTT ATCCTTGGCT GAGACATAAT GTTGACCTCA AGTTGAAGGA ACTTTTGGAG
AAATCAATCA GTAGAAGGCG GGACACCGAA GCCATACAGA AAGCCAAAAT CCTTTATTCA
TCCTGCATGA ATGAGAAAGC GATTGAAAAA GCAGATGCCA AGCCACTGCT ACACATCCTA
CGGCATTCAC CTTTCCGCTG GCCCGTGCTT GAATCTAATA TTGGCCCTGA AGGGGTTTGG
TCAGAGAGAA AGTTCAGCCT TCTGCAGACA CTTGCAACGT TTCGTGGTCA ATACAGCAAT
TCTGTGTTCA TCCGTTTGTA TGTGTCCCCT GATGACAAAG CATCCAATGA ACATATCTTG
AAGCTGGACC AAGCAACACT CTCCCTGGCC GTGAGGGAAG ACTACCTTGA TAACAGTACA
GAAGCCAAGT CTTATCGGGA TGCCCTTTAC AAGTTCATGG TGGATACTGC CGTGCTTTTA
GGAGCTAACA GTTCCAGAGC AGAGCATGAC ATGAAGTCAG TGCTCAGATT GGAAATTAAG
ATAGCTGAGA TAATGATTCC ACATGAAAAC CGAACCAGCG AGGCCATGTA CAACAAAATG
AACATTTCTG AACTGAGTGC TATGATTCCC CAGTTCGACT GGCTGGGCTA CATCAAGAAG
GTCATTGACA CCAGACTCTA CCCCCATCTG AAAGACATCA GCCCCTCCGA GAATGTGGTG
GTCCGCGTCC CGCAGTACTT TAAAGATTTG TTTAGGATAT TAGGGTCTGA GAGAAAGAAG
ACCATTGCCA ACTATTTGGT GTGGAGAATG GTTTATTCCA GAATTCCAAA CCTTAGCAGG
CGCTTTCAGT ATAGATGGCT GGAATTCTCA AGGGTAATCC AGGGGACCAC AACTTTGCTG
CCTCAATGGG ACAAATGTGT AAACTTTATT GAAAGTGCCC TCCCTTATGT TGTTGGAAAG
ATGTTTGTAG ATGTGTACTT CCAGGAAGAT AAGAAGGAAA TGATGGAGGA ATTGGTTGAG
GGCGTTCGCT GGGCCTTTAT TGACATGCTA GAGAAAGAAA ATGAGTGGAT GGATGCAGGA
ACGAAAAGGA AAGCCAAAGA AAAGGCGAGA GCTGTTTTGG CAAAAGTTGG CTATCCAGAG
TTTATAATGA ATGATACTCA TGTTAATGAA GACCTCAAAG CTATCAAGTT TTCAGAAGCC
GACTACTTTG GCAACGTCCT ACAAACTCGC AAGTATTTAG CACAGTCTGA TTTCTTCTGG
CTAAGAAAAG CCGTTCCAAA AACAGAGTGG TTTACAAATC CGACGACTGT CAATGCCTTC
TACAGTGCAT CCACCAACCA GATCCGATTT CCAGCAGGAG AGCTCCAGAA GCCTTTCTTT
TGGGGAACAG AATATCCTCG ATCTCTGAGT TATGGTGCTA TAGGAGTAAT TGTCGGACAT
GAATTTACAC ATGGATTTGA TAATAATGGT AGAAAATATG ATAAAAATGG AAACCTGGAT
CCTTGGTGGT CTACTGAATC AGAAGAAAAG TTTAAGGAAA AAACAAAATG CATGATTAAC
CAGTATAGCA ACTATTATTG GAAGAAAGCT GGCTTAAATG TCAAGGGGAA GAGGACCCTG
GGAGAAAATA TTGCTGATAA TGGAGGCCTG CGGGAAGCTT TTAGGGCTTA CAGGAAATGG
ATAAATGACA GAAGGCAGGG ACTTGAGGAG CCTCTTCTAC CAGGCATCAC ATTCACCAAC
AACCAGCTCT TCTTCCTGAG TTATGCTCAT GTGAGGTGCA ATTCCTACAG ACCAGAAGCT
GCCCGAGAAC AAGTCCAAAT TGGTGCTCAC AGTCCCCCTC AGTTTAGGGT CAATGGTGCA
ATTAGTAACT TTGAAGAATT CCAGAAAGCT TTTAACTGTC CACCCAATTC CACGATGAAC
AGAGGCATGG ACTCCTGCCG ACTCTGGTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_000435.3
CDS563..2812
Misc Feature(1)527..529(+)
Misc Feature(2)623..685(+)
Misc Feature(3)761..2785(+)
Misc Feature(4)782..2803(+)
Misc Feature(5)2174..2710(+)
Misc Feature(6)2300..2488(+)
Exon (1)1..680
Gene:PHEX
Gene Synonym:
Exon (2)681..749
Gene:PHEX
Gene Synonym:
Exon (3)750..911
Gene:PHEX
Gene Synonym:
Exon (4)912..998
Gene:PHEX
Gene Synonym:
Exon (5)999..1225
Gene:PHEX
Gene Synonym:
Exon (6)1226..1294
Gene:PHEX
Gene Synonym:
Exon (7)1295..1411
Gene:PHEX
Gene Synonym:
Exon (8)1412..1495
Gene:PHEX
Gene Synonym:
Exon (9)1496..1641
Gene:PHEX
Gene Synonym:
Exon (10)1642..1735
Gene:PHEX
Gene Synonym:
Exon (11)1736..1864
Gene:PHEX
Gene Synonym:
Exon (12)1865..1966
Gene:PHEX
Gene Synonym:
Exon (13)1967..2044
Gene:PHEX
Gene Synonym:
Exon (14)2045..2148
Gene:PHEX
Gene Synonym:
Exon (15)2149..2207
Gene:PHEX
Gene Synonym:
Exon (16)2208..2262
Gene:PHEX
Gene Synonym:
Exon (17)2263..2330
Gene:PHEX
Gene Synonym:
Exon (18)2331..2461
Gene:PHEX
Gene Synonym:
Exon (19)2462..2527
Gene:PHEX
Gene Synonym:
Exon (20)2528..2632
Gene:PHEX
Gene Synonym:
Exon (21)2633..2709
Gene:PHEX
Gene Synonym:
Exon (22)2710..6169
Gene:PHEX
Gene Synonym:
Translation
Position Chain Variation Link
20 20 a, g dbSNP:190284199
72 72 g, t dbSNP:182865352
103 103 c, t dbSNP:764250164
127 127 a, g dbSNP:555241989
150 150 a, g dbSNP:776891320
154 154 a, t dbSNP:573757656
169 169 a, c dbSNP:187601331
185 185 g, t dbSNP:178709
246 246 a, g dbSNP:371226416
253 253 c, t dbSNP:758949471
309 309 a, g dbSNP:770448887
355 355 a, g dbSNP:780387907
361 361 c, g dbSNP:777384160
417 417 a, g dbSNP:192414303
437 437 c, g dbSNP:185830047
442 442 -, g dbSNP:35301418
455 455 a, g dbSNP:149541983
473 473 a, g dbSNP:178710
525 525 a, c dbSNP:752602189
526 526 g, t dbSNP:201391816
530 530 c, t dbSNP:5951494
531 531 c, t dbSNP:750612939
540 540 a, g dbSNP:758504261
542 542 a, g dbSNP:780051359
545 545 c, t dbSNP:201251651
546 546 c, t dbSNP:755577853
552 552 c, t dbSNP:781538001
572 572 c, g dbSNP:147859619
580 580 c, g dbSNP:770026330
606 606 c, g dbSNP:773033853
609 609 a, g dbSNP:770920860
620 620 c, g dbSNP:770573978
621 621 -, a dbSNP:34610947
626 626 g, t dbSNP:773927462
635 635 a, g dbSNP:759110019
640 640 g, t dbSNP:767546324
643 643 c, t dbSNP:139862893
644 644 a, g dbSNP:760556268
666 666 c, t dbSNP:539005958
667 667 a, g dbSNP:763757285
693 693 a, t dbSNP:775529233
694 694 c, g dbSNP:778468346
704 704 c, g dbSNP:202074612
709 709 c, t dbSNP:768503558
718 718 a, g dbSNP:776477320
741 741 g, t dbSNP:756452995
743 743 a, g dbSNP:770630990
747 747 c, t dbSNP:145393882
748 748 a, g dbSNP:751752229
758 758 a, g dbSNP:779373231
771 771 c, g, t dbSNP:754929336
776 776 c, t dbSNP:768639876
788 788 c, g dbSNP:201394441
797 797 a, g dbSNP:761638747
807 807 a, g, t dbSNP:769541316
811 811 c, t dbSNP:145224279
812 812 a, g dbSNP:767642869
816 816 a, g dbSNP:137853269
819 819 a, g dbSNP:752781848
833 833 a, c dbSNP:375707069
842 842 a, g dbSNP:764744535
848 848 a, g dbSNP:149168023
850 850 a, g dbSNP:112836831
861 861 a, g dbSNP:765647670
864 864 a, g dbSNP:750103659
869 869 a, g dbSNP:758053428
880 880 a, g dbSNP:193922458
886 886 a, g dbSNP:779745439
904 904 a, g dbSNP:746551939
914 914 c, t dbSNP:772238348
929 929 a, g dbSNP:775756294
941 941 c, t dbSNP:375376231
942 942 a, g dbSNP:370698419
949 949 c, t dbSNP:777298207
955 955 c, t dbSNP:762351671
959 959 c, g dbSNP:151306376
981 981 c, t dbSNP:140678356
1002 1002 c, t dbSNP:749081778
1003 1003 a, g dbSNP:770726332
1005 1005 c, t dbSNP:775603606
1006 1006 c, t dbSNP:145881500
1012 1012 a, g dbSNP:768868675
1039 1039 c, t dbSNP:776784616
1042 1042 a, g dbSNP:761971488
1043 1043 c, t dbSNP:765714025
1044 1044 a, g dbSNP:138497409
1051 1051 a, g dbSNP:140231382
1053 1053 c, g dbSNP:766719010
1058 1058 c, t dbSNP:751230094
1059 1059 a, g dbSNP:150297950
1066 1066 c, t dbSNP:767157065
1067 1067 a, g dbSNP:187824835
1070 1070 c, g dbSNP:755595286
1080 1080 a, g dbSNP:777607846
1087 1087 a, c dbSNP:753767214
1099 1099 a, t dbSNP:137961493
1103 1103 g, t dbSNP:778710788
1129 1129 c, g dbSNP:747237564
1140 1140 c, t dbSNP:769066725
1141 1141 a, g dbSNP:781542537
1146 1146 a, g dbSNP:748279755
1175 1175 c, t dbSNP:769878509
1180 1180 g, t dbSNP:773617103
1182 1182 a, g dbSNP:763461759
1183 1183 c, t dbSNP:771208171
1187 1187 -, c dbSNP:36117823
1188 1188 c, g, t dbSNP:774768015
1193 1193 a, g dbSNP:370610267
1195 1195 c, t dbSNP:372618065
1215 1215 a, g dbSNP:774907553
1235 1235 a, g dbSNP:749327791
1240 1240 a, g dbSNP:771529993
1252 1252 c, g, t dbSNP:149487757
1253 1253 a, g dbSNP:376291775
1272 1272 a, t dbSNP:775148284
1286 1286 a, g dbSNP:760319054
1287 1287 c, g dbSNP:144007621
1292 1292 c, t dbSNP:763517570
1302 1302 a, g dbSNP:779431331
1317 1317 c, t dbSNP:267606945
1321 1321 a, g dbSNP:267606946
1329 1329 c, g dbSNP:746328622
1331 1331 c, g dbSNP:772441926
1333 1333 c, t dbSNP:142833404
1344 1344 a, g dbSNP:113219043
1359 1359 a, g dbSNP:775766235
1382 1382 a, g dbSNP:747331129
1383 1383 c, t dbSNP:768413746
1389 1389 a, g dbSNP:776124957
1391 1391 c, t dbSNP:761416628
1392 1392 a, t dbSNP:137853268
1402 1402 a, g dbSNP:147430384
1411 1411 a, g dbSNP:773293894
1422 1422 c, t dbSNP:746436151
1429 1429 a, g dbSNP:139771307
1437 1437 c, t dbSNP:768862054
1438 1438 a, c dbSNP:776367122
1441 1441 c, t dbSNP:772573976
1442 1442 a, g dbSNP:747696209
1446 1446 c, g dbSNP:769430757
1447 1447 -, cc dbSNP:193922460
1457 1457 a, g dbSNP:772921325
1461 1461 c, t dbSNP:762535711
1463 1463 a, c dbSNP:199893153
1465 1465 c, t dbSNP:142755818
1466 1466 a, g dbSNP:759411768
1470 1470 a, c dbSNP:767171186
1472 1472 a, g dbSNP:754106853
1480 1480 c, t dbSNP:150619847
1484 1484 a, g dbSNP:372663150
1498 1498 c, t dbSNP:760451270
1499 1499 a, g dbSNP:757539874
1507 1507 g, t dbSNP:750613071
1509 1509 g, t dbSNP:763042990
1510 1510 c, g dbSNP:766310950
1519 1519 a, g, t dbSNP:373261521
1533 1533 c, t dbSNP:199965602
1535 1535 a, c dbSNP:781713539
1544 1544 c, g dbSNP:201383931
1551 1551 g, t dbSNP:756512186
1558 1558 c, t dbSNP:139749399
1570 1570 c, t dbSNP:775973349
1571 1571 a, g dbSNP:770491624
1576 1576 c, t dbSNP:149793221
1583 1583 g, t dbSNP:745382329
1586 1586 c, t dbSNP:761575825
1587 1587 a, g dbSNP:376461141
1588 1588 c, t dbSNP:746847960
1589 1589 a, g dbSNP:768400503
1604 1604 a, g dbSNP:773436322
1607 1607 c, g dbSNP:763094620
1624 1624 a, g dbSNP:766616716
1639 1639 a, g dbSNP:774349246
1641 1641 a, g dbSNP:185862803
1645 1645 a, c dbSNP:753547432
1655 1655 c, t dbSNP:756929627
1673 1673 a, g dbSNP:759015845
1680 1680 c, t dbSNP:778616699
1681 1681 c, t dbSNP:753296824
1702 1702 a, g dbSNP:757894404
1711 1711 a, g dbSNP:779998335
1716 1716 a, g dbSNP:373233283
1724 1724 a, g dbSNP:746890776
1744 1744 a, g dbSNP:774598902
1747 1747 c, g dbSNP:371115510
1758 1758 c, t dbSNP:767652424
1764 1764 c, t dbSNP:145778165
1768 1768 a, g dbSNP:151234075
1782 1782 c, t dbSNP:764695823
1787 1787 c, t dbSNP:754314481
1810 1810 c, t dbSNP:757620472
1823 1823 a, g dbSNP:764839343
1829 1829 a, g dbSNP:750052547
1840 1840 c, t dbSNP:375729152
1846 1846 g, t dbSNP:757869310
1885 1885 c, t dbSNP:769336836
1886 1886 a, g dbSNP:777167473
1906 1906 c, t dbSNP:144911719
1921 1921 a, c dbSNP:202164519
1936 1936 c, t dbSNP:370746437
1942 1942 a, g dbSNP:750047503
1944 1944 c, t dbSNP:374873766
1945 1945 a, g dbSNP:77710864
1957 1957 c, g dbSNP:751117913
1966 1966 c, g dbSNP:754449807
1968 1968 c, t dbSNP:375593493
1988 1988 a, g dbSNP:766990714
1999 1999 a, g dbSNP:141436752
2008 2008 a, g dbSNP:756146878
2018 2018 a, g dbSNP:777560709
2023 2023 c, t dbSNP:765101791
2025 2025 a, t dbSNP:369896990
2032 2032 a, t dbSNP:371934258
2043 2043 a, c dbSNP:747180101
2060 2060 a, g dbSNP:765067632
2061 2061 a, c dbSNP:751837244
2063 2063 a, g dbSNP:373235530
2064 2064 a, g dbSNP:755284765
2077 2077 c, t dbSNP:764771688
2078 2078 a, g dbSNP:781248973
2083 2083 a, c dbSNP:748298612
2093 2093 a, c dbSNP:753522380
2094 2094 a, c dbSNP:778363445
2107 2107 c, g dbSNP:201266084
2116 2116 a, c dbSNP:749734873
2151 2151 a, g dbSNP:193922455
2157 2157 c, t dbSNP:767812044
2178 2178 c, t dbSNP:199935279
2188 2188 c, t dbSNP:752810184
2217 2217 c, t dbSNP:773244112
2218 2218 a, g dbSNP:143427381
2226 2226 c, t dbSNP:137853270
2237 2237 c, t dbSNP:762828809
2242 2242 c, t dbSNP:766026766
2261 2261 a, c, t dbSNP:137853271
2262 2262 a, g dbSNP:760870713
2264 2264 a, t dbSNP:768470624
2266 2266 c, t dbSNP:112728394
2284 2284 a, g dbSNP:780959710
2288 2288 a, g dbSNP:747692520
2296 2296 c, t dbSNP:769379550
2305 2305 a, g dbSNP:773291977
2310 2310 c, t dbSNP:762728667
2325 2325 a, t dbSNP:772130004
2335 2335 a, g dbSNP:781013156
2356 2356 c, t dbSNP:747743987
2371 2371 g, t dbSNP:755686699
2380 2380 a, g dbSNP:146055519
2381 2381 a, t dbSNP:748815816
2428 2428 c, t dbSNP:375441152
2478 2478 a, c dbSNP:111636676
2479 2479 a, c dbSNP:201343697
2480 2480 a, c dbSNP:756017274
2503 2503 c, t dbSNP:755885733
2511 2511 c, t dbSNP:193922456
2512 2512 a, g dbSNP:777456871
2514 2514 a, g dbSNP:748792378
2524 2524 c, t dbSNP:756752961
2543 2543 a, g dbSNP:774626712
2561 2561 g, t dbSNP:193922457
2574 2574 a, c dbSNP:759663012
2583 2583 a, c, t dbSNP:199517401
2587 2587 a, c dbSNP:760972913
2591 2591 a, c, g dbSNP:112577880
2592 2592 c, g dbSNP:764465237
2599 2599 c, t dbSNP:766459849
2614 2614 c, g dbSNP:373674171
2618 2618 a, c dbSNP:764784243
2630 2630 a, c dbSNP:200733697
2663 2663 g, t dbSNP:746918835
2670 2670 a, t dbSNP:747487296
2703 2703 a, g dbSNP:769039646
2713 2713 c, g dbSNP:772854418
2715 2715 a, c, g dbSNP:191028600
2723 2723 a, g dbSNP:766003166
2725 2725 c, g, t dbSNP:372307955
2735 2735 a, g dbSNP:767518128
2750 2750 g, t dbSNP:752729907
2758 2758 a, c dbSNP:376952568
2767 2767 c, t dbSNP:755989604
2769 2769 a, g dbSNP:367955819
2775 2775 c, t dbSNP:371825581
2776 2776 a, g dbSNP:140742016
2797 2797 c, g dbSNP:150112217
2802 2802 a, g dbSNP:138773278
2806 2806 c, g dbSNP:747154530
2813 2813 a, c dbSNP:754974866
2820 2820 a, g dbSNP:781727969
2831 2831 a, g dbSNP:374774539
2837 2837 c, t dbSNP:770279983
2859 2859 c, t dbSNP:370155243
2860 2860 a, g dbSNP:765479131
2870 2870 c, t dbSNP:183223600
2883 2883 a, g dbSNP:186466573
2922 2922 a, t dbSNP:780324969
2979 2979 a, g dbSNP:751689587
3019 3019 a, g dbSNP:755389049
3030 3030 a, c dbSNP:141594056
3034 3034 c, t dbSNP:748724335
3037 3037 a, g dbSNP:770275990
3039 3039 c, g dbSNP:765787001
3094 3094 g, t dbSNP:373526963
3117 3117 a, g dbSNP:189715720
3139 3139 c, g dbSNP:748836233
3147 3147 a, g dbSNP:770308822
3151 3151 a, g dbSNP:773553690
3173 3173 c, t dbSNP:182654518
3200 3200 a, g dbSNP:759086924
3237 3237 a, g dbSNP:775420101
3268 3268 a, g dbSNP:147507544
3284 3284 g, t dbSNP:763522632
3292 3292 c, t dbSNP:766900352
3340 3340 a, g dbSNP:113813269
3386 3386 c, g dbSNP:776361459
3403 3403 a, g dbSNP:369147272
3483 3483 g, t dbSNP:751959768
3500 3500 -, tgag dbSNP:750660265
3511 3511 c, g dbSNP:145080586
3517 3517 -, a dbSNP:766317343
3580 3580 c, t dbSNP:754747451
3589 3589 a, c dbSNP:188175876
3632 3632 a, g dbSNP:5951739
3635 3635 a, g dbSNP:41309575
3660 3660 -, t dbSNP:753078908
3684 3684 c, g, t dbSNP:376254574
3685 3685 a, g dbSNP:149673099
3707 3707 a, g dbSNP:749711087
3710 3710 c, t dbSNP:145476860
3732 3732 a, c dbSNP:192770679
3744 3744 a, g dbSNP:183619109
3760 3760 c, t dbSNP:187522891
3790 3790 -, t dbSNP:200473244
3792 3792 a, tagtgcaaag dbSNP:386824235
3792 3792 -, tagtgcaaa dbSNP:200544019
3792 3792 -, tagtgcaa dbSNP:79379908
3794 3794 -, gtgcaaag dbSNP:199638664
3795 3795 a, t dbSNP:777794098
3796 3796 a, g dbSNP:749259065
3799 3799 -, aag dbSNP:746800228
3801 3801 a, g dbSNP:200248764
3927 3927 a, g dbSNP:192098973
3933 3933 a, c dbSNP:757161203
3959 3959 a, g dbSNP:148478140
3967 3967 c, t dbSNP:761631760
4036 4036 c, t dbSNP:369535826
4067 4067 -, gtgtgtgtgtgtggtgtgtgtgt dbSNP:766550946
4068 4068 -, gtgtgtgtgt dbSNP:771619032
4068 4068 -, gt dbSNP:749752907
4099 4099 -, gtgtgtgtgt dbSNP:59496974
4117 4117 g, t dbSNP:774285492
4142 4142 c, t dbSNP:16981889
4220 4220 c, t dbSNP:184539861
4290 4290 a, t dbSNP:752876880
4301 4301 a, t dbSNP:377467619
4302 4302 -, a dbSNP:540966419
4314 4314 -, aat dbSNP:762309910
4315 4315 -, a, at dbSNP:71879575
4316 4316 a, t dbSNP:59285690
4316 4316 -, t dbSNP:372076236
4318 4318 a, t dbSNP:59180400
4318 4318 -, t dbSNP:370627436
4353 4353 a, c dbSNP:764345252
4356 4356 c, t dbSNP:5951740
4379 4379 g, t dbSNP:753777813
4463 4463 c, t dbSNP:757697615
4473 4473 c, t dbSNP:5951741
4494 4494 a, t dbSNP:5951742
4560 4560 c, g dbSNP:191203770
4573 4573 c, g dbSNP:745656887
4597 4597 a, g dbSNP:145670027
4600 4600 g, t dbSNP:768926927
4691 4691 c, g dbSNP:184499919
4772 4772 a, g dbSNP:748292420
4803 4803 a, g dbSNP:373843573
4823 4823 -, tcac dbSNP:776288532
4831 4831 c, t dbSNP:769805151
4942 4942 c, t dbSNP:773406106
4962 4962 -, caaa dbSNP:559255193
4962 4962 a, c dbSNP:1894417
4973 4973 a, g dbSNP:766992148
5001 5001 c, t dbSNP:189815560
5014 5014 c, g dbSNP:773135056
5039 5039 c, t dbSNP:759647942
5073 5073 a, g dbSNP:759926909
5077 5077 c, t dbSNP:772094808
5082 5082 a, g dbSNP:141005414
5114 5114 a, c dbSNP:1894418
5125 5125 a, g dbSNP:138745617
5255 5255 a, g dbSNP:752248178
5274 5274 c, g dbSNP:760339525
5286 5286 g, t dbSNP:149429660
5330 5330 a, g dbSNP:718302
5339 5339 a, c dbSNP:377429675
5391 5391 c, t dbSNP:147114489
5392 5392 a, g dbSNP:750920468
5406 5406 a, g dbSNP:758003630
5419 5419 a, t dbSNP:138443284
5462 5462 a, c dbSNP:751295282
5468 5468 a, c dbSNP:763558376
5497 5497 a, g dbSNP:144006455
5547 5547 -, cctc dbSNP:773840982
5579 5579 c, t dbSNP:186570524
5674 5674 a, c dbSNP:769591275
5790 5790 a, g dbSNP:147159870
5829 5829 a, g dbSNP:148632928
5839 5839 g, t dbSNP:141223944
5879 5879 c, t dbSNP:775541115
5899 5899 a, c dbSNP:150716965
5946 5946 -, a dbSNP:779634495
5950 5950 c, t dbSNP:768770074
5951 5951 a, g dbSNP:776842545
5952 5952 c, t dbSNP:139065358
5953 5953 c, t dbSNP:778752986
5962 5962 a, g dbSNP:144125698
5987 5987 a, t dbSNP:750231550
6016 6016 c, g dbSNP:751015608
6081 6081 c, t dbSNP:763520621
6099 6099 c, t dbSNP:146520078
6101 6101 c, t dbSNP:533345329
6124 6124 g, t dbSNP:57128317

Target ORF information:

RefSeq Version NM_000444
Organism Homo sapiens (human)
Definition Homo sapiens phosphate regulating endopeptidase homolog, X-linked (PHEX), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000444

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGGAAGCAG AAACAGGGAG CAGCGTGGAG ACTGGAAAGA AGGCCAACAG AGGCACTCGA 
ATTGCCCTGG TCGTGTTTGT CGGTGGCACC CTAGTTCTGG GCACGATCCT CTTTCTAGTG
AGTCAAGGTC TCTTAAGTCT CCAAGCTAAA CAGGAGTACT GCCTGAAGCC AGAATGCATC
GAAGCGGCTG CTGCCATCTT AAGTAAAGTA AATCTGTCTG TGGATCCTTG TGATAATTTC
TTCCGGTTCG CTTGTGATGG CTGGATAAGC AATAATCCAA TTCCCGAAGA TATGCCAAGC
TATGGGGTTT ATCCTTGGCT GAGACATAAT GTTGACCTCA AGTTGAAGGA ACTTTTGGAG
AAATCAATCA GTAGAAGGCG GGACACCGAA GCCATACAGA AAGCCAAAAT CCTTTATTCA
TCCTGCATGA ATGAGAAAGC GATTGAAAAA GCAGATGCCA AGCCACTGCT ACACATCCTA
CGGCATTCAC CTTTCCGCTG GCCCGTGCTT GAATCTAATA TTGGCCCTGA AGGGGTTTGG
TCAGAGAGAA AGTTCAGCCT TCTGCAGACA CTTGCAACGT TTCGTGGTCA ATACAGCAAT
TCTGTGTTCA TCCGTTTGTA TGTGTCCCCT GATGACAAAG CATCCAATGA ACATATCTTG
AAGCTGGACC AAGCAACACT CTCCCTGGCC GTGAGGGAAG ACTACCTTGA TAACAGTACA
GAAGCCAAGT CTTATCGGGA TGCCCTTTAC AAGTTCATGG TGGATACTGC CGTGCTTTTA
GGAGCTAACA GTTCCAGAGC AGAGCATGAC ATGAAGTCAG TGCTCAGATT GGAAATTAAG
ATAGCTGAGA TAATGATTCC ACATGAAAAC CGAACCAGCG AGGCCATGTA CAACAAAATG
AACATTTCTG AACTGAGTGC TATGATTCCC CAGTTCGACT GGCTGGGCTA CATCAAGAAG
GTCATTGACA CCAGACTCTA CCCCCATCTG AAAGACATCA GCCCCTCCGA GAATGTGGTG
GTCCGCGTCC CGCAGTACTT TAAAGATTTG TTTAGGATAT TAGGGTCTGA GAGAAAGAAG
ACCATTGCCA ACTATTTGGT GTGGAGAATG GTTTATTCCA GAATTCCAAA CCTTAGCAGG
CGCTTTCAGT ATAGATGGCT GGAATTCTCA AGGGTAATCC AGGGGACCAC AACTTTGCTG
CCTCAATGGG ACAAATGTGT AAACTTTATT GAAAGTGCCC TCCCTTATGT TGTTGGAAAG
ATGTTTGTAG ATGTGTACTT CCAGGAAGAT AAGAAGGAAA TGATGGAGGA ATTGGTTGAG
GGCGTTCGCT GGGCCTTTAT TGACATGCTA GAGAAAGAAA ATGAGTGGAT GGATGCAGGA
ACGAAAAGGA AAGCCAAAGA AAAGGCGAGA GCTGTTTTGG CAAAAGTTGG CTATCCAGAG
TTTATAATGA ATGATACTCA TGTTAATGAA GACCTCAAAG CTATCAAGTT TTCAGAAGCC
GACTACTTTG GCAACGTCCT ACAAACTCGC AAGTATTTAG CACAGTCTGA TTTCTTCTGG
CTAAGAAAAG CCGTTCCAAA AACAGAGTGG TTTACAAATC CGACGACTGT CAATGCCTTC
TACAGTGCAT CCACCAACCA GATCCGATTT CCAGCAGGAG AGCTCCAGAA GCCTTTCTTT
TGGGGAACAG AATATCCTCG ATCTCTGAGT TATGGTGCTA TAGGAGTAAT TGTCGGACAT
GAATTTACAC ATGGATTTGA TAATAATGGT AGAAAATATG ATAAAAATGG AAACCTGGAT
CCTTGGTGGT CTACTGAATC AGAAGAAAAG TTTAAGGAAA AAACAAAATG CATGATTAAC
CAGTATAGCA ACTATTATTG GAAGAAAGCT GGCTTAAATG TCAAGGGGAA GAGGACCCTG
GGAGAAAATA TTGCTGATAA TGGAGGCCTG CGGGAAGCTT TTAGGGCTTA CAGGAAATGG
ATAAATGACA GAAGGCAGGG ACTTGAGGAG CCTCTTCTAC CAGGCATCAC ATTCACCAAC
AACCAGCTCT TCTTCCTGAG TTATGCTCAT GTGAGGTGCA ATTCCTACAG ACCAGAAGCT
GCCCGAGAAC AAGTCCAAAT TGGTGCTCAC AGTCCCCCTC AGTTTAGGGT CAATGGTGCA
ATTAGTAACT TTGAAGAATT CCAGAAAGCT TTTAACTGTC CACCCAATTC CACGATGAAC
AGAGGCATGG ACTCCTGCCG ACTCTGGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20451
Accession Version NM_001282754.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2088bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product phosphate-regulating neutral endopeptidase isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U82970.1, Y10196.1, AK298030.1, BC105057.1 and AK301528.1. Summary: The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]. Transcript Variant: This variant (2) lacks an alternate exon in the 3' coding region, which results in a frameshift and an early stop codon, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK298030.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGGAAGCAG AAACAGGGAG CAGCGTGGAG ACTGGAAAGA AGGCCAACAG AGGCACTCGA 
ATTGCCCTGG TCGTGTTTGT CGGTGGCACC CTAGTTCTGG GCACGATCCT CTTTCTAGTG
AGTCAAGGTC TCTTAAGTCT CCAAGCTAAA CAGGAGTACT GCCTGAAGCC AGAATGCATC
GAAGCGGCTG CTGCCATCTT AAGTAAAGTA AATCTGTCTG TGGATCCTTG TGATAATTTC
TTCCGGTTCG CTTGTGATGG CTGGATAAGC AATAATCCAA TTCCCGAAGA TATGCCAAGC
TATGGGGTTT ATCCTTGGCT GAGACATAAT GTTGACCTCA AGTTGAAGGA ACTTTTGGAG
AAATCAATCA GTAGAAGGCG GGACACCGAA GCCATACAGA AAGCCAAAAT CCTTTATTCA
TCCTGCATGA ATGAGAAAGC GATTGAAAAA GCAGATGCCA AGCCACTGCT ACACATCCTA
CGGCATTCAC CTTTCCGCTG GCCCGTGCTT GAATCTAATA TTGGCCCTGA AGGGGTTTGG
TCAGAGAGAA AGTTCAGCCT TCTGCAGACA CTTGCAACGT TTCGTGGTCA ATACAGCAAT
TCTGTGTTCA TCCGTTTGTA TGTGTCCCCT GATGACAAAG CATCCAATGA ACATATCTTG
AAGCTGGACC AAGCAACACT CTCCCTGGCC GTGAGGGAAG ACTACCTTGA TAACAGTACA
GAAGCCAAGT CTTATCGGGA TGCCCTTTAC AAGTTCATGG TGGATACTGC CGTGCTTTTA
GGAGCTAACA GTTCCAGAGC AGAGCATGAC ATGAAGTCAG TGCTCAGATT GGAAATTAAG
ATAGCTGAGA TAATGATTCC ACATGAAAAC CGAACCAGCG AGGCCATGTA CAACAAAATG
AACATTTCTG AACTGAGTGC TATGATTCCC CAGTTCGACT GGCTGGGCTA CATCAAGAAG
GTCATTGACA CCAGACTCTA CCCCCATCTG AAAGACATCA GCCCCTCCGA GAATGTGGTG
GTCCGCGTCC CGCAGTACTT TAAAGATTTG TTTAGGATAT TAGGGTCTGA GAGAAAGAAG
ACCATTGCCA ACTATTTGGT GTGGAGAATG GTTTATTCCA GAATTCCAAA CCTTAGCAGG
CGCTTTCAGT ATAGATGGCT GGAATTCTCA AGGGTAATCC AGGGGACCAC AACTTTGCTG
CCTCAATGGG ACAAATGTGT AAACTTTATT GAAAGTGCCC TCCCTTATGT TGTTGGAAAG
ATGTTTGTAG ATGTGTACTT CCAGGAAGAT AAGAAGGAAA TGATGGAGGA ATTGGTTGAG
GGCGTTCGCT GGGCCTTTAT TGACATGCTA GAGAAAGAAA ATGAGTGGAT GGATGCAGGA
ACGAAAAGGA AAGCCAAAGA AAAGGCGAGA GCTGTTTTGG CAAAAGTTGG CTATCCAGAG
TTTATAATGA ATGATACTCA TGTTAATGAA GACCTCAAAG CTATCAAGTT TTCAGAAGCC
GACTACTTTG GCAACGTCCT ACAAACTCGC AAGTATTTAG CACAGTCTGA TTTCTTCTGG
CTAAGAAAAG CCGTTCCAAA AACAGAGTGG TTTACAAATC CGACGACTGT CAATGCCTTC
TACAGTGCAT CCACCAACCA GATCCGATTT CCAGCAGGAG AGCTCCAGAA GCCTTTCTTT
TGGGGAACAG AATATCCTCG ATCTCTGAGT TATGGTGCTA TAGGAGTAAT TGTCGGACAT
GAATTTACAC ATGGATTTGA TAATAATGGT AGAAAATATG ATAAAAATGG AAACCTGGAT
CCTTGGTGGT CTACTGAATC AGAAGAAAAG TTTAAGGAAA AAACAAAATG CATGATTAAC
CAGTATAGCA ACTATTATTG GAAGAAAGCT GGCTTAAATG TCAAGGGGAA GAGGACCCTG
GGAGAAAATA TTGCTGATAA TGGAGGCCTG CGGGAAGCTT TTAGGGCTTA CAGGAAATGG
ATAAATGACA GAAGGCAGGG ACTTGAGGAG CCTCTTCTAC CAGGCATCAC ATTCACCAAC
AACCAGCTCT TCTTCCTGAG TTATGCTCAT GGTCAATGGT GCAATTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001269683.1
CDS563..2650
Misc Feature(1)527..529(+)
Misc Feature(2)623..685(+)
Misc Feature(3)782..2647(+)
Misc Feature(4)2174..2629(+)
Misc Feature(5)2300..2488(+)
Exon (1)1..680
Gene:PHEX
Gene Synonym:
Exon (2)681..749
Gene:PHEX
Gene Synonym:
Exon (3)750..911
Gene:PHEX
Gene Synonym:
Exon (4)912..998
Gene:PHEX
Gene Synonym:
Exon (5)999..1225
Gene:PHEX
Gene Synonym:
Exon (6)1226..1294
Gene:PHEX
Gene Synonym:
Exon (7)1295..1411
Gene:PHEX
Gene Synonym:
Exon (8)1412..1495
Gene:PHEX
Gene Synonym:
Exon (9)1496..1641
Gene:PHEX
Gene Synonym:
Exon (10)1642..1735
Gene:PHEX
Gene Synonym:
Exon (11)1736..1864
Gene:PHEX
Gene Synonym:
Exon (12)1865..1966
Gene:PHEX
Gene Synonym:
Exon (13)1967..2044
Gene:PHEX
Gene Synonym:
Exon (14)2045..2148
Gene:PHEX
Gene Synonym:
Exon (15)2149..2207
Gene:PHEX
Gene Synonym:
Exon (16)2208..2262
Gene:PHEX
Gene Synonym:
Exon (17)2263..2330
Gene:PHEX
Gene Synonym:
Exon (18)2331..2461
Gene:PHEX
Gene Synonym:
Exon (19)2462..2527
Gene:PHEX
Gene Synonym:
Exon (20)2528..2632
Gene:PHEX
Gene Synonym:
Exon (21)2633..6092
Gene:PHEX
Gene Synonym:
Translation
Position Chain Variation Link
20 20 a, g dbSNP:190284199
72 72 g, t dbSNP:182865352
103 103 c, t dbSNP:764250164
127 127 a, g dbSNP:555241989
150 150 a, g dbSNP:776891320
154 154 a, t dbSNP:573757656
169 169 a, c dbSNP:187601331
185 185 g, t dbSNP:178709
246 246 a, g dbSNP:371226416
253 253 c, t dbSNP:758949471
309 309 a, g dbSNP:770448887
355 355 a, g dbSNP:780387907
361 361 c, g dbSNP:777384160
417 417 a, g dbSNP:192414303
437 437 c, g dbSNP:185830047
442 442 -, g dbSNP:35301418
455 455 a, g dbSNP:149541983
473 473 a, g dbSNP:178710
525 525 a, c dbSNP:752602189
526 526 g, t dbSNP:201391816
530 530 c, t dbSNP:5951494
531 531 c, t dbSNP:750612939
540 540 a, g dbSNP:758504261
542 542 a, g dbSNP:780051359
545 545 c, t dbSNP:201251651
546 546 c, t dbSNP:755577853
552 552 c, t dbSNP:781538001
572 572 c, g dbSNP:147859619
580 580 c, g dbSNP:770026330
606 606 c, g dbSNP:773033853
609 609 a, g dbSNP:770920860
620 620 c, g dbSNP:770573978
621 621 -, a dbSNP:34610947
626 626 g, t dbSNP:773927462
635 635 a, g dbSNP:759110019
640 640 g, t dbSNP:767546324
643 643 c, t dbSNP:139862893
644 644 a, g dbSNP:760556268
666 666 c, t dbSNP:539005958
667 667 a, g dbSNP:763757285
693 693 a, t dbSNP:775529233
694 694 c, g dbSNP:778468346
704 704 c, g dbSNP:202074612
709 709 c, t dbSNP:768503558
718 718 a, g dbSNP:776477320
741 741 g, t dbSNP:756452995
743 743 a, g dbSNP:770630990
747 747 c, t dbSNP:145393882
748 748 a, g dbSNP:751752229
758 758 a, g dbSNP:779373231
771 771 c, g, t dbSNP:754929336
776 776 c, t dbSNP:768639876
788 788 c, g dbSNP:201394441
797 797 a, g dbSNP:761638747
807 807 a, g, t dbSNP:769541316
811 811 c, t dbSNP:145224279
812 812 a, g dbSNP:767642869
816 816 a, g dbSNP:137853269
819 819 a, g dbSNP:752781848
833 833 a, c dbSNP:375707069
842 842 a, g dbSNP:764744535
848 848 a, g dbSNP:149168023
850 850 a, g dbSNP:112836831
861 861 a, g dbSNP:765647670
864 864 a, g dbSNP:750103659
869 869 a, g dbSNP:758053428
880 880 a, g dbSNP:193922458
886 886 a, g dbSNP:779745439
904 904 a, g dbSNP:746551939
914 914 c, t dbSNP:772238348
929 929 a, g dbSNP:775756294
941 941 c, t dbSNP:375376231
942 942 a, g dbSNP:370698419
949 949 c, t dbSNP:777298207
955 955 c, t dbSNP:762351671
959 959 c, g dbSNP:151306376
981 981 c, t dbSNP:140678356
1002 1002 c, t dbSNP:749081778
1003 1003 a, g dbSNP:770726332
1005 1005 c, t dbSNP:775603606
1006 1006 c, t dbSNP:145881500
1012 1012 a, g dbSNP:768868675
1039 1039 c, t dbSNP:776784616
1042 1042 a, g dbSNP:761971488
1043 1043 c, t dbSNP:765714025
1044 1044 a, g dbSNP:138497409
1051 1051 a, g dbSNP:140231382
1053 1053 c, g dbSNP:766719010
1058 1058 c, t dbSNP:751230094
1059 1059 a, g dbSNP:150297950
1066 1066 c, t dbSNP:767157065
1067 1067 a, g dbSNP:187824835
1070 1070 c, g dbSNP:755595286
1080 1080 a, g dbSNP:777607846
1087 1087 a, c dbSNP:753767214
1099 1099 a, t dbSNP:137961493
1103 1103 g, t dbSNP:778710788
1129 1129 c, g dbSNP:747237564
1140 1140 c, t dbSNP:769066725
1141 1141 a, g dbSNP:781542537
1146 1146 a, g dbSNP:748279755
1175 1175 c, t dbSNP:769878509
1180 1180 g, t dbSNP:773617103
1182 1182 a, g dbSNP:763461759
1183 1183 c, t dbSNP:771208171
1187 1187 -, c dbSNP:36117823
1188 1188 c, g, t dbSNP:774768015
1193 1193 a, g dbSNP:370610267
1195 1195 c, t dbSNP:372618065
1215 1215 a, g dbSNP:774907553
1235 1235 a, g dbSNP:749327791
1240 1240 a, g dbSNP:771529993
1252 1252 c, g, t dbSNP:149487757
1253 1253 a, g dbSNP:376291775
1272 1272 a, t dbSNP:775148284
1286 1286 a, g dbSNP:760319054
1287 1287 c, g dbSNP:144007621
1292 1292 c, t dbSNP:763517570
1302 1302 a, g dbSNP:779431331
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1321 1321 a, g dbSNP:267606946
1329 1329 c, g dbSNP:746328622
1331 1331 c, g dbSNP:772441926
1333 1333 c, t dbSNP:142833404
1344 1344 a, g dbSNP:113219043
1359 1359 a, g dbSNP:775766235
1382 1382 a, g dbSNP:747331129
1383 1383 c, t dbSNP:768413746
1389 1389 a, g dbSNP:776124957
1391 1391 c, t dbSNP:761416628
1392 1392 a, t dbSNP:137853268
1402 1402 a, g dbSNP:147430384
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1422 1422 c, t dbSNP:746436151
1429 1429 a, g dbSNP:139771307
1437 1437 c, t dbSNP:768862054
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1446 1446 c, g dbSNP:769430757
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1457 1457 a, g dbSNP:772921325
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1463 1463 a, c dbSNP:199893153
1465 1465 c, t dbSNP:142755818
1466 1466 a, g dbSNP:759411768
1470 1470 a, c dbSNP:767171186
1472 1472 a, g dbSNP:754106853
1480 1480 c, t dbSNP:150619847
1484 1484 a, g dbSNP:372663150
1498 1498 c, t dbSNP:760451270
1499 1499 a, g dbSNP:757539874
1507 1507 g, t dbSNP:750613071
1509 1509 g, t dbSNP:763042990
1510 1510 c, g dbSNP:766310950
1519 1519 a, g, t dbSNP:373261521
1533 1533 c, t dbSNP:199965602
1535 1535 a, c dbSNP:781713539
1544 1544 c, g dbSNP:201383931
1551 1551 g, t dbSNP:756512186
1558 1558 c, t dbSNP:139749399
1570 1570 c, t dbSNP:775973349
1571 1571 a, g dbSNP:770491624
1576 1576 c, t dbSNP:149793221
1583 1583 g, t dbSNP:745382329
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1587 1587 a, g dbSNP:376461141
1588 1588 c, t dbSNP:746847960
1589 1589 a, g dbSNP:768400503
1604 1604 a, g dbSNP:773436322
1607 1607 c, g dbSNP:763094620
1624 1624 a, g dbSNP:766616716
1639 1639 a, g dbSNP:774349246
1641 1641 a, g dbSNP:185862803
1645 1645 a, c dbSNP:753547432
1655 1655 c, t dbSNP:756929627
1673 1673 a, g dbSNP:759015845
1680 1680 c, t dbSNP:778616699
1681 1681 c, t dbSNP:753296824
1702 1702 a, g dbSNP:757894404
1711 1711 a, g dbSNP:779998335
1716 1716 a, g dbSNP:373233283
1724 1724 a, g dbSNP:746890776
1744 1744 a, g dbSNP:774598902
1747 1747 c, g dbSNP:371115510
1758 1758 c, t dbSNP:767652424
1764 1764 c, t dbSNP:145778165
1768 1768 a, g dbSNP:151234075
1782 1782 c, t dbSNP:764695823
1787 1787 c, t dbSNP:754314481
1810 1810 c, t dbSNP:757620472
1823 1823 a, g dbSNP:764839343
1829 1829 a, g dbSNP:750052547
1840 1840 c, t dbSNP:375729152
1846 1846 g, t dbSNP:757869310
1885 1885 c, t dbSNP:769336836
1886 1886 a, g dbSNP:777167473
1906 1906 c, t dbSNP:144911719
1921 1921 a, c dbSNP:202164519
1936 1936 c, t dbSNP:370746437
1942 1942 a, g dbSNP:750047503
1944 1944 c, t dbSNP:374873766
1945 1945 a, g dbSNP:77710864
1957 1957 c, g dbSNP:751117913
1966 1966 c, g dbSNP:754449807
1968 1968 c, t dbSNP:375593493
1988 1988 a, g dbSNP:766990714
1999 1999 a, g dbSNP:141436752
2008 2008 a, g dbSNP:756146878
2018 2018 a, g dbSNP:777560709
2023 2023 c, t dbSNP:765101791
2025 2025 a, t dbSNP:369896990
2032 2032 a, t dbSNP:371934258
2043 2043 a, c dbSNP:747180101
2060 2060 a, g dbSNP:765067632
2061 2061 a, c dbSNP:751837244
2063 2063 a, g dbSNP:373235530
2064 2064 a, g dbSNP:755284765
2077 2077 c, t dbSNP:764771688
2078 2078 a, g dbSNP:781248973
2083 2083 a, c dbSNP:748298612
2093 2093 a, c dbSNP:753522380
2094 2094 a, c dbSNP:778363445
2107 2107 c, g dbSNP:201266084
2116 2116 a, c dbSNP:749734873
2151 2151 a, g dbSNP:193922455
2157 2157 c, t dbSNP:767812044
2178 2178 c, t dbSNP:199935279
2188 2188 c, t dbSNP:752810184
2217 2217 c, t dbSNP:773244112
2218 2218 a, g dbSNP:143427381
2226 2226 c, t dbSNP:137853270
2237 2237 c, t dbSNP:762828809
2242 2242 c, t dbSNP:766026766
2261 2261 a, c, t dbSNP:137853271
2262 2262 a, g dbSNP:760870713
2264 2264 a, t dbSNP:768470624
2266 2266 c, t dbSNP:112728394
2284 2284 a, g dbSNP:780959710
2288 2288 a, g dbSNP:747692520
2296 2296 c, t dbSNP:769379550
2305 2305 a, g dbSNP:773291977
2310 2310 c, t dbSNP:762728667
2325 2325 a, t dbSNP:772130004
2335 2335 a, g dbSNP:781013156
2356 2356 c, t dbSNP:747743987
2371 2371 g, t dbSNP:755686699
2380 2380 a, g dbSNP:146055519
2381 2381 a, t dbSNP:748815816
2428 2428 c, t dbSNP:375441152
2478 2478 a, c dbSNP:111636676
2479 2479 a, c dbSNP:201343697
2480 2480 a, c dbSNP:756017274
2503 2503 c, t dbSNP:755885733
2511 2511 c, t dbSNP:193922456
2512 2512 a, g dbSNP:777456871
2514 2514 a, g dbSNP:748792378
2524 2524 c, t dbSNP:756752961
2543 2543 a, g dbSNP:774626712
2561 2561 g, t dbSNP:193922457
2574 2574 a, c dbSNP:759663012
2583 2583 a, c, t dbSNP:199517401
2587 2587 a, c dbSNP:760972913
2591 2591 a, c, g dbSNP:112577880
2592 2592 c, g dbSNP:764465237
2599 2599 c, t dbSNP:766459849
2614 2614 c, g dbSNP:373674171
2618 2618 a, c dbSNP:764784243
2630 2630 a, c dbSNP:200733697
2636 2636 c, g dbSNP:772854418
2638 2638 a, c, g dbSNP:191028600
2646 2646 a, g dbSNP:766003166
2648 2648 c, g, t dbSNP:372307955
2658 2658 a, g dbSNP:767518128
2673 2673 g, t dbSNP:752729907
2681 2681 a, c dbSNP:376952568
2690 2690 c, t dbSNP:755989604
2692 2692 a, g dbSNP:367955819
2698 2698 c, t dbSNP:371825581
2699 2699 a, g dbSNP:140742016
2720 2720 c, g dbSNP:150112217
2725 2725 a, g dbSNP:138773278
2729 2729 c, g dbSNP:747154530
2736 2736 a, c dbSNP:754974866
2743 2743 a, g dbSNP:781727969
2754 2754 a, g dbSNP:374774539
2760 2760 c, t dbSNP:770279983
2782 2782 c, t dbSNP:370155243
2783 2783 a, g dbSNP:765479131
2793 2793 c, t dbSNP:183223600
2806 2806 a, g dbSNP:186466573
2845 2845 a, t dbSNP:780324969
2902 2902 a, g dbSNP:751689587
2942 2942 a, g dbSNP:755389049
2953 2953 a, c dbSNP:141594056
2957 2957 c, t dbSNP:748724335
2960 2960 a, g dbSNP:770275990
2962 2962 c, g dbSNP:765787001
3017 3017 g, t dbSNP:373526963
3040 3040 a, g dbSNP:189715720
3062 3062 c, g dbSNP:748836233
3070 3070 a, g dbSNP:770308822
3074 3074 a, g dbSNP:773553690
3096 3096 c, t dbSNP:182654518
3123 3123 a, g dbSNP:759086924
3160 3160 a, g dbSNP:775420101
3191 3191 a, g dbSNP:147507544
3207 3207 g, t dbSNP:763522632
3215 3215 c, t dbSNP:766900352
3263 3263 a, g dbSNP:113813269
3309 3309 c, g dbSNP:776361459
3326 3326 a, g dbSNP:369147272
3406 3406 g, t dbSNP:751959768
3423 3423 -, tgag dbSNP:750660265
3434 3434 c, g dbSNP:145080586
3440 3440 -, a dbSNP:766317343
3503 3503 c, t dbSNP:754747451
3512 3512 a, c dbSNP:188175876
3555 3555 a, g dbSNP:5951739
3558 3558 a, g dbSNP:41309575
3583 3583 -, t dbSNP:753078908
3607 3607 c, g, t dbSNP:376254574
3608 3608 a, g dbSNP:149673099
3630 3630 a, g dbSNP:749711087
3633 3633 c, t dbSNP:145476860
3655 3655 a, c dbSNP:192770679
3667 3667 a, g dbSNP:183619109
3683 3683 c, t dbSNP:187522891
3713 3713 -, t dbSNP:200473244
3715 3715 a, tagtgcaaag dbSNP:386824235
3715 3715 -, tagtgcaaa dbSNP:200544019
3715 3715 -, tagtgcaa dbSNP:79379908
3717 3717 -, gtgcaaag dbSNP:199638664
3718 3718 a, t dbSNP:777794098
3719 3719 a, g dbSNP:749259065
3722 3722 -, aag dbSNP:746800228
3724 3724 a, g dbSNP:200248764
3850 3850 a, g dbSNP:192098973
3856 3856 a, c dbSNP:757161203
3882 3882 a, g dbSNP:148478140
3890 3890 c, t dbSNP:761631760
3959 3959 c, t dbSNP:369535826
3990 3990 -, gtgtgtgtgtgtggtgtgtgtgt dbSNP:766550946
3991 3991 -, gtgtgtgtgt dbSNP:771619032
3991 3991 -, gt dbSNP:749752907
4022 4022 -, gtgtgtgtgt dbSNP:59496974
4040 4040 g, t dbSNP:774285492
4065 4065 c, t dbSNP:16981889
4143 4143 c, t dbSNP:184539861
4213 4213 a, t dbSNP:752876880
4224 4224 a, t dbSNP:377467619
4225 4225 -, a dbSNP:540966419
4237 4237 -, aat dbSNP:762309910
4238 4238 -, a, at dbSNP:71879575
4239 4239 a, t dbSNP:59285690
4239 4239 -, t dbSNP:372076236
4241 4241 a, t dbSNP:59180400
4241 4241 -, t dbSNP:370627436
4276 4276 a, c dbSNP:764345252
4279 4279 c, t dbSNP:5951740
4302 4302 g, t dbSNP:753777813
4386 4386 c, t dbSNP:757697615
4396 4396 c, t dbSNP:5951741
4417 4417 a, t dbSNP:5951742
4483 4483 c, g dbSNP:191203770
4496 4496 c, g dbSNP:745656887
4520 4520 a, g dbSNP:145670027
4523 4523 g, t dbSNP:768926927
4614 4614 c, g dbSNP:184499919
4695 4695 a, g dbSNP:748292420
4726 4726 a, g dbSNP:373843573
4746 4746 -, tcac dbSNP:776288532
4754 4754 c, t dbSNP:769805151
4865 4865 c, t dbSNP:773406106
4885 4885 -, caaa dbSNP:559255193
4885 4885 a, c dbSNP:1894417
4896 4896 a, g dbSNP:766992148
4924 4924 c, t dbSNP:189815560
4937 4937 c, g dbSNP:773135056
4962 4962 c, t dbSNP:759647942
4996 4996 a, g dbSNP:759926909
5000 5000 c, t dbSNP:772094808
5005 5005 a, g dbSNP:141005414
5037 5037 a, c dbSNP:1894418
5048 5048 a, g dbSNP:138745617
5178 5178 a, g dbSNP:752248178
5197 5197 c, g dbSNP:760339525
5209 5209 g, t dbSNP:149429660
5253 5253 a, g dbSNP:718302
5262 5262 a, c dbSNP:377429675
5314 5314 c, t dbSNP:147114489
5315 5315 a, g dbSNP:750920468
5329 5329 a, g dbSNP:758003630
5342 5342 a, t dbSNP:138443284
5385 5385 a, c dbSNP:751295282
5391 5391