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PLG plasminogen [Homo sapiens (human)]

Gene Symbol PLG
Entrez Gene ID 5340
Full Name plasminogen
Synonyms
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6q26

Summary The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]. lac of sum
Disorder MIM:

173350

Disorder Html: Plasminogen Tochigi disease (3); Thrombophilia, dysplasminogenemic
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OHu22912 NM_000301 Homo sapiens plasminogen (PLG), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK Not in stock 12-14 Starting from $99.00
OHu22248 NM_001168338 Homo sapiens plasminogen (PLG), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK Not in stock 7-9 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OHu22912D
Sequence Information ORF Nucleotide Sequence (Length: 2433bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product plasminogen isoform 1 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DR004070.1, M74220.1, X05199.1 and AL109933.25. This sequence is a reference standard in the RefSeqGene project. On Dec 3, 2009 this sequence version replaced gi:186972151. Summary: The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X05199.1, BC060513.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2145122 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGGAACATA AGGAAGTGGT TCTTCTACTT CTTTTATTTC TGAAATCAGG TCAAGGAGAG 
CCTCTGGATG ACTATGTGAA TACCCAGGGG GCTTCACTGT TCAGTGTCAC TAAGAAGCAG
CTGGGAGCAG GAAGTATAGA AGAATGTGCA GCAAAATGTG AGGAGGACGA AGAATTCACC
TGCAGGGCAT TCCAATATCA CAGTAAAGAG CAACAATGTG TGATAATGGC TGAAAACAGG
AAGTCCTCCA TAATCATTAG GATGAGAGAT GTAGTTTTAT TTGAAAAGAA AGTGTATCTC
TCAGAGTGCA AGACTGGGAA TGGAAAGAAC TACAGAGGGA CGATGTCCAA AACAAAAAAT
GGCATCACCT GTCAAAAATG GAGTTCCACT TCTCCCCACA GACCTAGATT CTCACCTGCT
ACACACCCCT CAGAGGGACT GGAGGAGAAC TACTGCAGGA ATCCAGACAA CGATCCGCAG
GGGCCCTGGT GCTATACTAC TGATCCAGAA AAGAGATATG ACTACTGCGA CATTCTTGAG
TGTGAAGAGG AATGTATGCA TTGCAGTGGA GAAAACTATG ACGGCAAAAT TTCCAAGACC
ATGTCTGGAC TGGAATGCCA GGCCTGGGAC TCTCAGAGCC CACACGCTCA TGGATACATT
CCTTCCAAAT TTCCAAACAA GAACCTGAAG AAGAATTACT GTCGTAACCC CGATAGGGAG
CTGCGGCCTT GGTGTTTCAC CACCGACCCC AACAAGCGCT GGGAACTTTG TGACATCCCC
CGCTGCACAA CACCTCCACC ATCTTCTGGT CCCACCTACC AGTGTCTGAA GGGAACAGGT
GAAAACTATC GCGGGAATGT GGCTGTTACC GTGTCCGGGC ACACCTGTCA GCACTGGAGT
GCACAGACCC CTCACACACA TAACAGGACA CCAGAAAACT TCCCCTGCAA AAATTTGGAT
GAAAACTACT GCCGCAATCC TGACGGAAAA AGGGCCCCAT GGTGCCATAC AACCAACAGC
CAAGTGCGGT GGGAGTACTG TAAGATACCG TCCTGTGACT CCTCCCCAGT ATCCACGGAA
CAATTGGCTC CCACAGCACC ACCTGAGCTA ACCCCTGTGG TCCAGGACTG CTACCATGGT
GATGGACAGA GCTACCGAGG CACATCCTCC ACCACCACCA CAGGAAAGAA GTGTCAGTCT
TGGTCATCTA TGACACCACA CCGGCACCAG AAGACCCCAG AAAACTACCC AAATGCTGGC
CTGACAATGA ACTACTGCAG GAATCCAGAT GCCGATAAAG GCCCCTGGTG TTTTACCACA
GACCCCAGCG TCAGGTGGGA GTACTGCAAC CTGAAAAAAT GCTCAGGAAC AGAAGCGAGT
GTTGTAGCAC CTCCGCCTGT TGTCCTGCTT CCAGATGTAG AGACTCCTTC CGAAGAAGAC
TGTATGTTTG GGAATGGGAA AGGATACCGA GGCAAGAGGG CGACCACTGT TACTGGGACG
CCATGCCAGG ACTGGGCTGC CCAGGAGCCC CATAGACACA GCATTTTCAC TCCAGAGACA
AATCCACGGG CGGGTCTGGA AAAAAATTAC TGCCGTAACC CTGATGGTGA TGTAGGTGGT
CCCTGGTGCT ACACGACAAA TCCAAGAAAA CTTTACGACT ACTGTGATGT CCCTCAGTGT
GCGGCCCCTT CATTTGATTG TGGGAAGCCT CAAGTGGAGC CGAAGAAATG TCCTGGAAGG
GTTGTAGGGG GGTGTGTGGC CCACCCACAT TCCTGGCCCT GGCAAGTCAG TCTTAGAACA
AGGTTTGGAA TGCACTTCTG TGGAGGCACC TTGATATCCC CAGAGTGGGT GTTGACTGCT
GCCCACTGCT TGGAGAAGTC CCCAAGGCCT TCATCCTACA AGGTCATCCT GGGTGCACAC
CAAGAAGTGA ATCTCGAACC GCATGTTCAG GAAATAGAAG TGTCTAGGCT GTTCTTGGAG
CCCACACGAA AAGATATTGC CTTGCTAAAG CTAAGCAGTC CTGCCGTCAT CACTGACAAA
GTAATCCCAG CTTGTCTGCC ATCCCCAAAT TATGTGGTCG CTGACCGGAC CGAATGTTTC
ATCACTGGCT GGGGAGAAAC CCAAGGTACT TTTGGAGCTG GCCTTCTCAA GGAAGCCCAG
CTCCCTGTGA TTGAGAATAA AGTGTGCAAT CGCTATGAGT TTCTGAATGG AAGAGTCCAA
TCCACCGAAC TCTGTGCTGG GCATTTGGCC GGAGGCACTG ACAGTTGCCA GGGTGACAGT
GGAGGTCCTC TGGTTTGCTT CGAGAAGGAC AAATACATTT TACAAGGAGT CACTTCTTGG
GGTCTTGGCT GTGCACGCCC CAATAAGCCT GGTGTCTATG TTCGTGTTTC AAGGTTTGTT
ACTTGGATTG AGGGAGTGAT GAGAAATAAT TAA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_000292.1
CDS113..2545
Misc Feature(1)53..55(+)
Misc Feature(2)167..169(+)
Misc Feature(3)224..403(+)
Misc Feature(4)224..268(+)
Misc Feature(5)344..349(+)
Misc Feature(6)344..346(+)
Misc Feature(7)398..400(+)
Misc Feature(8)398..400(+)
Misc Feature(9)398..400(+)
Misc Feature(10)416..658(+)
Misc Feature(11)446..448(+)
Misc Feature(12)491..631(+)
Misc Feature(13)656..898(+)
Misc Feature(14)674..1060(+)
Misc Feature(15)692..694(+)
Misc Feature(16)737..874(+)
Misc Feature(17)914..916(+)
Misc Feature(18)926..1171(+)
Misc Feature(19)962..964(+)
Misc Feature(20)1007..1144(+)
Misc Feature(21)1034..1036(+)
Misc Feature(22)1205..1207(+)
Misc Feature(23)1235..1477(+)
Misc Feature(24)1268..1270(+)
Misc Feature(25)1313..1450(+)
Misc Feature(26)1484..1486(+)
Misc Feature(27)1505..1507(+)
Misc Feature(28)1508..1513(+)
Misc Feature(29)1508..1510(+)
Misc Feature(30)1508..1510(+)
Misc Feature(31)1544..1795(+)
Misc Feature(32)1553..1792(+)
Misc Feature(33)1580..1582(+)
Misc Feature(34)1616..1741(+)
Misc Feature(35)1625..1768(+)
Misc Feature(36)1703..1777(+)
Misc Feature(37)1757..1759(+)
Misc Feature(38)1799..1801(+)
Misc Feature(39)1811..2167(+)
Misc Feature(40)1841..1867(+)
Misc Feature(41)1850..2521(+)
Misc Feature(42)1850..1855(+)
Misc Feature(43)1850..1852(+)
Misc Feature(44)1850..1852(+)
Misc Feature(45)1853..2524(+)
Misc Feature(46)1853..1855(+)
Misc Feature(47)1901..1903(+)
Misc Feature(48)1901..1903(+)
Misc Feature(49)1976..2392(+)
Misc Feature(50)2012..2014(+)
Misc Feature(51)2120..2122(+)
Misc Feature(52)2150..2152(+)
Misc Feature(53)2261..2263(+)
Misc Feature(54)2291..2293(+)
Misc Feature(55)2372..2455(+)
Exon (1)1..161
Gene:PLG
Gene Synonym:
Exon (2)162..297
Gene:PLG
Gene Synonym:
Exon (3)298..404
Gene:PLG
Gene Synonym:
Exon (4)405..519
Gene:PLG
Gene Synonym:
Exon (5)520..659
Gene:PLG
Gene Synonym:
Exon (6)660..780
Gene:PLG
Gene Synonym:
Exon (7)781..899
Gene:PLG
Gene Synonym:
Exon (8)900..1062
Gene:PLG
Gene Synonym:
Exon (9)1063..1208
Gene:PLG
Gene Synonym:
Exon (10)1209..1368
Gene:PLG
Gene Synonym:
Exon (11)1369..1550
Gene:PLG
Gene Synonym:
Exon (12)1551..1699
Gene:PLG
Gene Synonym:
Exon (13)1700..1793
Gene:PLG
Gene Synonym:
Exon (14)1794..1914
Gene:PLG
Gene Synonym:
Exon (15)1915..1989
Gene:PLG
Gene Synonym:
Exon (16)1990..2130
Gene:PLG
Gene Synonym:
Exon (17)2131..2237
Gene:PLG
Gene Synonym:
Exon (18)2238..2383
Gene:PLG
Gene Synonym:
Exon (19)2384..3538
Gene:PLG
Gene Synonym:
Translation
Position Chain Variation Link
30 30 g, t dbSNP:547015291
31 31 c, t dbSNP:773235483
36 36 a, g dbSNP:570081943
39 39 c, t dbSNP:532887563
40 40 a, g dbSNP:538436952
47 47 c, g dbSNP:549803884
64 64 c, t dbSNP:113759707
65 65 a, g dbSNP:745586549
74 74 c, t dbSNP:187896045
77 77 a, g dbSNP:770018389
78 78 a, g dbSNP:4252060
80 80 a, c dbSNP:749742948
81 81 a, c dbSNP:769161551
84 84 c, t dbSNP:571997762
85 85 c, t dbSNP:774345563
87 87 c, t dbSNP:761797094
90 90 -, g dbSNP:776527411
92 92 g, t dbSNP:767695607
101 101 g, t dbSNP:773284230
105 105 a, g dbSNP:374037660
112 112 a, c dbSNP:764892205
118 118 a, g dbSNP:752552388
124 124 a, g dbSNP:4252061
129 129 c, t dbSNP:764121149
131 131 g, t dbSNP:751602282
137 137 c, t dbSNP:756696418
148 148 a, g dbSNP:371469289
154 154 c, g dbSNP:750008400
162 162 a, g, t dbSNP:755657852
168 168 a, g dbSNP:753547888
173 173 c, t dbSNP:755313936
175 175 c, t dbSNP:4063623
179 179 a, g dbSNP:779290753
180 180 a, t dbSNP:748555046
181 181 c, t dbSNP:532295436
185 185 c, t dbSNP:777646481
189 189 a, t dbSNP:747105638
195 195 c, t dbSNP:771191021
196 196 a, c, g dbSNP:776968748
199 199 a, g dbSNP:768527258
203 203 c, g dbSNP:2340665
209 209 a, c, g dbSNP:774229224
211 211 c, g, t dbSNP:140570408
215 215 a, g dbSNP:760167202
217 217 c, t dbSNP:765923801
224 224 a, g dbSNP:73015965
226 226 c, g dbSNP:372999008
227 227 a, c dbSNP:138353396
235 235 g, t dbSNP:372972552
238 238 a, g dbSNP:374911072
246 246 a, g dbSNP:753109342
247 247 c, t dbSNP:1049571
249 249 c, g, t dbSNP:1049573
253 253 a, g dbSNP:778328614
259 259 c, t dbSNP:747516899
270 270 a, g dbSNP:757377776
272 272 a, g dbSNP:781448572
277 277 a, g dbSNP:746034511
278 278 a, g dbSNP:770158666
280 280 c, t dbSNP:144100362
281 281 a, g dbSNP:4252070
289 289 c, t dbSNP:771821751
311 311 c, t dbSNP:140789621
314 314 a, t dbSNP:754051719
315 315 c, g dbSNP:540661824
322 322 a, g dbSNP:777476575
333 333 a, t dbSNP:761016779
338 338 a, t dbSNP:770768604
341 341 a, g dbSNP:781084043
344 344 a, g dbSNP:745842913
349 349 c, t dbSNP:769305013
351 351 g, t dbSNP:774881372
352 352 g, t dbSNP:762605639
367 367 c, g dbSNP:768201749
376 376 a, g dbSNP:189824042
378 378 a, c, g dbSNP:143079629
385 385 a, c dbSNP:768047126
393 393 c, t dbSNP:373442935
401 401 a, c dbSNP:750930821
405 405 c, t dbSNP:777253416
408 408 a, t dbSNP:759510598
412 412 c, t dbSNP:61731705
418 418 a, c, g dbSNP:144747470
421 421 c, t dbSNP:758640124
424 424 a, g dbSNP:767238787
425 425 a, g dbSNP:750185991
426 426 c, t dbSNP:756007372
427 427 a, t dbSNP:779846532
428 428 a, g, t dbSNP:141284301
429 429 c, g dbSNP:778599053
430 430 a, g dbSNP:747756137
435 435 c, g, t dbSNP:545865924
442 442 c, t dbSNP:4757
453 453 c, t dbSNP:139357983
454 454 a, g dbSNP:776970597
459 459 a, c dbSNP:760118758
469 469 a, t dbSNP:377275189
473 473 a, g dbSNP:775557740
480 480 c, t dbSNP:370856655
507 507 a, c dbSNP:764292529
510 510 a, g dbSNP:61731706
511 511 a, c dbSNP:4252186
515 515 c, t dbSNP:199833895
517 517 c, t dbSNP:544452740
529 529 c, t dbSNP:374989402
533 533 a, g dbSNP:565890939
538 538 c, g dbSNP:777371711
539 539 c, t dbSNP:751122910
540 540 c, t dbSNP:756944864
547 547 g, t dbSNP:781343369
551 551 c, t dbSNP:746222696
552 552 c, t dbSNP:770198253
553 553 -, gga dbSNP:755522987
560 560 a, t dbSNP:780520011
571 571 a, g dbSNP:144153702
577 577 a, g dbSNP:368638671
578 578 a, c, g dbSNP:756533019
580 580 a, c dbSNP:146415258
583 583 c, t dbSNP:372617319
584 584 a, g dbSNP:141045811
588 588 c, t dbSNP:201792453
589 589 a, g, t dbSNP:555922023
595 595 a, g, t dbSNP:575946180
596 596 a, c dbSNP:751081547
605 605 c, t dbSNP:139828885
613 613 g, t dbSNP:554946329
617 617 a, c dbSNP:143256245
620 620 a, g dbSNP:750128891
625 625 c, g dbSNP:374619723
626 626 a, g dbSNP:145535174
627 627 g, t dbSNP:749750806
634 634 c, t dbSNP:368221997
637 637 c, t dbSNP:371986721
640 640 a, c, t dbSNP:558599800
641 641 a, g dbSNP:374903528
646 646 c, t dbSNP:773535126
650 650 a, g dbSNP:369353385
651 651 a, g dbSNP:769663919
660 660 a, g dbSNP:768381731
672 672 a, g dbSNP:377016135
684 684 a, g dbSNP:761689224
688 688 c, t dbSNP:774596197
693 693 a, t dbSNP:150072546
694 694 c, t dbSNP:145192723
710 710 a, g dbSNP:149145958
712 712 c, t dbSNP:766015667
714 714 c, t dbSNP:753493236
715 715 g, t dbSNP:755349893
724 724 a, g dbSNP:369715307
734 734 g, t dbSNP:201014517
735 735 a, c, t dbSNP:758842289
740 740 a, g dbSNP:751682018
744 744 a, c dbSNP:757465792
757 757 a, c, t dbSNP:781540328
758 758 a, g dbSNP:374234922
763 763 c, t dbSNP:775795598
765 765 g, t dbSNP:778597933
767 767 c, t dbSNP:151092364
770 770 a, g, t dbSNP:377537611
772 772 c, t dbSNP:760165235
774 774 c, t dbSNP:770480023
777 777 c, t dbSNP:566440089
786 786 c, g dbSNP:749693342
797 797 c, g dbSNP:752070023
803 803 -, aag dbSNP:121918034
814 814 c, t dbSNP:762435382
816 816 a, g dbSNP:121918030
823 823 a, c, t dbSNP:200226472
824 824 a, g dbSNP:756287836
826 826 c, t dbSNP:766497393
827 827 a, g dbSNP:758627124
832 832 a, g dbSNP:142604256
836 836 a, c, t dbSNP:758158723
837 837 a, g dbSNP:746890698
850 850 a, c dbSNP:146910079
855 855 c, t dbSNP:139012522
856 856 a, c, t dbSNP:745353237
857 857 a, g, t dbSNP:532027310
861 861 c, t dbSNP:372026592
863 863 a, c dbSNP:774872002
864 864 a, g dbSNP:762347588
869 869 c, t dbSNP:767909495
870 870 a, g dbSNP:143034754
875 875 a, c, g dbSNP:760649328
883 883 c, t dbSNP:14224
884 884 a, g dbSNP:138242513
893 893 c, t dbSNP:763808748
894 894 a, g dbSNP:4252187
910 910 a, c dbSNP:756093439
919 919 c, t dbSNP:779647096
925 925 c, g, t dbSNP:774956297
926 926 a, c dbSNP:754598185
935 935 c, t dbSNP:778686781
949 949 a, g dbSNP:553595975
950 950 a, g dbSNP:747875226
952 952 a, t dbSNP:772285632
963 963 a, g, t dbSNP:371746732
964 964 c, t dbSNP:760216173
965 965 g, t dbSNP:771422389
967 967 a, g, t dbSNP:202061577
968 968 a, g dbSNP:763975431
969 969 a, g dbSNP:775647219
982 982 c, t dbSNP:763256179
983 983 a, g dbSNP:564003153
988 988 c, t dbSNP:753737813
989 989 a, g dbSNP:750240361
996 996 c, t dbSNP:760457084
1005 1005 a, g dbSNP:757014437
1024 1024 a, t dbSNP:766409637
1030 1030 -, a dbSNP:749118624
1038 1038 c, g dbSNP:753879928
1051 1051 c, t dbSNP:754506581
1054 1054 c, t dbSNP:1130656
1055 1055 c, t dbSNP:752244249
1060 1060 a, c dbSNP:758084577
1062 1062 a, t dbSNP:777354540
1063 1063 a, g dbSNP:751210887
1070 1070 c, g dbSNP:757573859
1073 1073 a, g dbSNP:76192728
1081 1081 c, t dbSNP:781555655
1086 1086 a, g, t dbSNP:746314667
1096 1096 c, t dbSNP:780494393
1108 1108 c, t dbSNP:571406329
1119 1119 a, t dbSNP:749375422
1127 1127 a, g dbSNP:200604924
1131 1131 c, g dbSNP:549550780
1135 1135 a, t dbSNP:138051887
1136 1136 a, c, g dbSNP:199771790
1138 1138 a, g dbSNP:759482781
1139 1139 c, t dbSNP:142647215
1140 1140 a, g dbSNP:775335671
1159 1159 a, g dbSNP:535713437
1160 1160 c, t dbSNP:763543916
1162 1162 a, g dbSNP:775045516
1166 1166 c, t dbSNP:751173845
1171 1171 c, g, t dbSNP:781616117
1174 1174 c, t dbSNP:756915624
1175 1175 c, t dbSNP:767801113
1176 1176 a, c dbSNP:750784310
1180 1180 a, g dbSNP:756530078
1183 1183 a, g dbSNP:146041064
1187 1187 a, g dbSNP:201973253
1195 1195 a, g dbSNP:13231
1202 1202 c, t dbSNP:369616186
1209 1209 c, t dbSNP:766685527
1219 1219 g, t dbSNP:754325596
1224 1224 a, c, g, t dbSNP:780940385
1226 1226 c, g dbSNP:758597842
1232 1232 g, t dbSNP:121918028
1236 1236 a, g dbSNP:142086839
1240 1240 c, g dbSNP:747572282
1250 1250 a, g dbSNP:769578807
1253 1253 g, t dbSNP:376572197
1255 1255 c, t dbSNP:749182016
1258 1258 a, g dbSNP:769370242
1260 1260 a, g dbSNP:370326625
1262 1262 a, g dbSNP:778073217
1268 1268 a, c dbSNP:771610738
1269 1269 a, g dbSNP:772811538
1276 1276 a, g dbSNP:760271152
1279 1279 c, t dbSNP:372689013
1283 1283 a, g dbSNP:754160565
1288 1288 c, t dbSNP:760014589
1310 1310 c, t dbSNP:773226077
1316 1316 c, t dbSNP:765815120
1322 1322 a, g dbSNP:753294113
1324 1324 a, g dbSNP:758508931
1334 1334 c, t dbSNP:4252119
1335 1335 a, g dbSNP:751773919
1341 1341 a, g dbSNP:757425055
1344 1344 a, c dbSNP:781542891
1346 1346 a, g dbSNP:749021358
1348 1348 a, c dbSNP:768546781
1360 1360 c, t dbSNP:778793475
1365 1365 a, c dbSNP:748115521
1366 1366 c, t dbSNP:771522609
1369 1369 c, t dbSNP:770222035
1371 1371 a, g dbSNP:139071351
1381 1381 g, t dbSNP:763477607
1393 1393 a, g dbSNP:149909079
1397 1397 c, t dbSNP:774970719
1404 1404 a, c dbSNP:761768856
1405 1405 c, t dbSNP:767669117
1406 1406 a, c, g dbSNP:770460362
1410 1410 a, c dbSNP:764948729
1414 1414 c, t dbSNP:774014073
1420 1420 c, g dbSNP:370807852
1431 1431 c, t dbSNP:758250276
1432 1432 a, g dbSNP:758987677
1433 1433 a, g dbSNP:777552429
1440 1440 a, g dbSNP:746995108
1441 1441 a, c, t dbSNP:756670030
1442 1442 a, g dbSNP:574500945
1446 1446 c, g dbSNP:769564214
1447 1447 c, g, t dbSNP:371661937
1451 1451 -, g dbSNP:36089164
1468 1468 a, g dbSNP:769185216
1469 1469 a, g dbSNP:774683115
1470 1470 a, t dbSNP:1804181
1475 1475 c, t dbSNP:762405404
1480 1480 a, g dbSNP:771989121
1481 1481 a, g dbSNP:773350034
1483 1483 a, g dbSNP:760815242
1488 1488 c, g, t dbSNP:771575586
1489 1489 a, g dbSNP:754112260
1492 1492 a, t dbSNP:116573785
1497 1497 c, t dbSNP:142565890
1502 1502 a, c dbSNP:374635068
1505 1505 c, t dbSNP:757219403
1506 1506 c, t dbSNP:374995543
1507 1507 a, g dbSNP:368155641
1515 1515 -, ttta dbSNP:759923340
1515 1515 c, t dbSNP:755731990
1526 1526 a, g dbSNP:4252125
1528 1528 a, t dbSNP:748980932
1529 1529 a, g dbSNP:768855743
1531 1531 -, ag dbSNP:753306661
1543 1543 c, t dbSNP:4699
1544 1544 a, g dbSNP:748537055
1546 1546 a, c, g dbSNP:532399913
1547 1547 g, t dbSNP:121918032
1558 1558 a, g dbSNP:753483846
1570 1570 a, g, t dbSNP:141539231
1580 1580 a, c, t dbSNP:367707054
1581 1581 a, g dbSNP:140537724
1588 1588 a, g dbSNP:778225357
1591 1591 a, g dbSNP:747532986
1593 1593 a, c, t dbSNP:4252128
1594 1594 a, g dbSNP:745998201
1611 1611 c, t dbSNP:140970354
1612 1612 a, g dbSNP:775623839
1615 1615 a, t dbSNP:150227219
1618 1618 c, t dbSNP:774954253
1622 1622 c, g dbSNP:767246436
1631 1631 g, t dbSNP:138011858
1632 1632 c, t dbSNP:372603134
1639 1639 g, t dbSNP:765921106
1645 1645 a, c, t dbSNP:753395776
1650 1650 a, t dbSNP:764925493
1651 1651 c, t dbSNP:752334341
1662 1662 c, t dbSNP:377265821
1669 1669 a, g dbSNP:768434850
1671 1671 a, c, g dbSNP:747448179
1679 1679 c, t dbSNP:4252129
1684 1684 a, g dbSNP:745937967
1686 1686 a, g dbSNP:533258034
1706 1706 c, t dbSNP:761700164
1711 1711 -, cc dbSNP:749135572
1727 1727 c, g dbSNP:750924392
1733 1733 a, c dbSNP:756169141
1739 1739 c, t dbSNP:780012024
1746 1746 c, t dbSNP:769824406
1747 1747 a, g dbSNP:370774291
1749 1749 c, t dbSNP:768997330
1750 1750 a, g dbSNP:779336978
1752 1752 a, g dbSNP:746781558
1768 1768 c, t dbSNP:113153850
1769 1769 a, c, g dbSNP:182937977
1779 1779 a, g dbSNP:769278141
1795 1795 g, t dbSNP:779248927
1808 1808 c, g dbSNP:569278081
1824 1824 a, g dbSNP:770804626
1827 1827 a, t dbSNP:780849993
1833 1833 c, t dbSNP:745737842
1834 1834 a, g dbSNP:146030266
1836 1836 a, g dbSNP:775543829
1847 1847 a, g dbSNP:138728014
1856 1856 g, t dbSNP:768183951
1860 1860 a, c, g dbSNP:551058645
1863 1863 a, g dbSNP:767857630
1875 1875 a, g dbSNP:202141531
1876 1876 c, t dbSNP:201308812
1883 1883 c, t dbSNP:121918029
1888 1888 a, g dbSNP:766775422
1891 1891 c, t dbSNP:368271141
1899 1899 g, t dbSNP:372520102
1919 1919 a, g dbSNP:777232742
1922 1922 a, g dbSNP:576700968
1936 1936 a, c dbSNP:372193015
1939 1939 a, c dbSNP:765908641
1946 1946 a, t dbSNP:752807651
1949 1949 a, t dbSNP:758551184
1960 1960 a, c, g dbSNP:121918031
1961 1961 c, g dbSNP:751836569
1962 1962 -, tgt dbSNP:768371532
1962 1962 a, t dbSNP:755814893
1963 1963 g, t dbSNP:779911364
1964 1964 c, t dbSNP:4252195
1970 1970 a, g dbSNP:121918027
1972 1972 c, t dbSNP:778879651
1981 1981 c, t dbSNP:144424879
1994 1994 c, t dbSNP:778793621
2008 2008 c, t dbSNP:375051997
2010 2010 a, g dbSNP:757799843
2015 2015 a, g dbSNP:777359514
2018 2018 a, g dbSNP:746578884
2047 2047 c, t dbSNP:182180648
2048 2048 a, g dbSNP:369196761
2051 2051 c, t dbSNP:746201137
2052 2052 c, t dbSNP:187157735
2053 2053 a, c, g dbSNP:61731712
2062 2062 a, g dbSNP:768551185
2070 2070 a, g dbSNP:774484989
2071 2071 a, g dbSNP:761856716
2074 2074 g, t dbSNP:4252196
2080 2080 a, g dbSNP:750685941
2090 2090 c, g dbSNP:759288464
2097 2097 c, t dbSNP:765041629
2099 2099 c, t dbSNP:752522150
2100 2100 a, c, g dbSNP:576737789
2101 2101 a, g dbSNP:751054851
2109 2109 c, t dbSNP:764647453
2136 2136 c, t dbSNP:755339005
2137 2137 a, c, t dbSNP:370325463
2138 2138 a, g dbSNP:142551860
2139 2139 a, t dbSNP:17857492
2143 2143 c, g dbSNP:773286811
2157 2157 a, t dbSNP:147175166
2170 2170 a, g dbSNP:771132412
2174 2174 a, t dbSNP:776753449
2180 2180 a, g dbSNP:762765275
2192 2192 a, c, g dbSNP:763815176
2194 2194 c, t dbSNP:4252170
2195 2195 a, g dbSNP:181030365
2198 2198 c, g, t dbSNP:144869703
2199 2199 a, g dbSNP:147930532
2200 2200 a, g dbSNP:753464654
2203 2203 a, c, t dbSNP:755323263
2204 2204 a, g dbSNP:201323384
2206 2206 a, g dbSNP:557700523
2207 2207 c, t dbSNP:778315137
2220 2220 a, g dbSNP:747055991
2234 2234 c, g dbSNP:770942860
2236 2236 a, c dbSNP:781424107
2246 2246 a, g dbSNP:202074006
2250 2250 c, t dbSNP:773236077
2256 2256 c, t dbSNP:760544829
2265 2265 a, g dbSNP:778725428
2271 2271 a, g dbSNP:200731501
2280 2280 c, t dbSNP:770409778
2281 2281 a, g dbSNP:776003920
2291 2291 a, g dbSNP:759147567
2296 2296 a, g dbSNP:140580870
2303 2303 c, t dbSNP:752373837
2304 2304 a, g dbSNP:150065136
2306 2306 c, t dbSNP:145177652
2307 2307 a, g dbSNP:149148300
2323 2323 a, t dbSNP:558651254
2339 2339 a, g dbSNP:757693607
2342 2342 c, g dbSNP:781757563
2344 2344 a, c dbSNP:750439464
2361 2361 c, t dbSNP:138277465
2362 2362 c, t dbSNP:756267226
2363 2363 a, g dbSNP:121918033
2367 2367 a, g dbSNP:771304689
2369 2369 a, g dbSNP:749552173
2371 2371 c, t dbSNP:4252175
2398 2398 g, t dbSNP:11060
2414 2414 a, g dbSNP:199619244
2419 2419 a, g dbSNP:766570209
2420 2420 g, t dbSNP:754054583
2429 2429 a, g dbSNP:755235233
2440 2440 a, c dbSNP:779342869
2449 2449 c, t dbSNP:746746494
2450 2450 c, t dbSNP:757121130
2453 2453 a, g dbSNP:780956197
2468 2468 c, t dbSNP:200857824
2469 2469 a, g dbSNP:376140019
2476 2476 a, t dbSNP:774970398
2478 2478 a, g dbSNP:748865566
2491 2491 c, t dbSNP:768267732
2522 2522 a, g dbSNP:774103177
2525 2525 c, g dbSNP:762034623
2526 2526 a, g dbSNP:767955927
2532 2532 a, t dbSNP:773525076
2539 2539 -, taat dbSNP:772711456
2551 2551 c, t dbSNP:370809839
2552 2552 a, g dbSNP:181878511
2553 2553 a, g dbSNP:753960234
2556 2556 a, g dbSNP:755145357
2559 2559 a, g dbSNP:765351054
2562 2562 a, g dbSNP:752982395
2566 2566 c, t dbSNP:756939818
2567 2567 a, g, t dbSNP:781058780
2586 2586 a, c dbSNP:756043581
2590 2590 a, g dbSNP:6690
2590 2590 a, g dbSNP:57037765
2592 2592 c, t dbSNP:748775608
2593 2593 a, g, t dbSNP:150437480
2596 2596 g, t dbSNP:747840571
2597 2597 g, t dbSNP:772267049
2657 2657 c, t dbSNP:571532014
2666 2666 c, t dbSNP:41267833
2701 2701 c, g dbSNP:375006147
2709 2709 c, t dbSNP:372763926
2716 2716 c, g dbSNP:140323614
2785 2785 c, g dbSNP:777094383
2830 2830 a, t dbSNP:201911710
2830 2830 -, t dbSNP:4252177
2832 2832 a, tt dbSNP:369537132
2835 2835 -, a dbSNP:200319086
2877 2877 a, c dbSNP:145476240
2883 2883 a, g dbSNP:535600388
2899 2899 c, g dbSNP:186439505
2916 2916 a, g dbSNP:528224234
2918 2918 a, g dbSNP:189281351
2939 2939 c, g dbSNP:557814370
2956 2956 c, t dbSNP:117330062
2959 2959 c, t dbSNP:577562347
2960 2960 a, g dbSNP:543542776
2972 2972 g, t dbSNP:563192670
2987 2987 c, t dbSNP:529491948
3006 3006 c, t dbSNP:770227121
3031 3031 c, t dbSNP:783169
3040 3040 c, t dbSNP:181010511
3043 3043 g, t dbSNP:763236227
3046 3046 a, g dbSNP:783168
3050 3050 c, t dbSNP:551657790
3061 3061 c, t dbSNP:185993564
3064 3064 c, g dbSNP:530772141
3082 3082 a, g dbSNP:4252178
3102 3102 -, g dbSNP:369140852
3105 3105 c, g dbSNP:373956668
3110 3110 a, g dbSNP:783167
3142 3142 a, g, t dbSNP:1050912
3176 3176 a, g dbSNP:147387427
3193 3193 a, g dbSNP:565857424
3200 3200 a, c dbSNP:139573422
3226 3226 c, t dbSNP:557756245
3259 3259 a, g dbSNP:376724881
3299 3299 a, g dbSNP:111899543
3320 3320 a, g dbSNP:4252179
3323 3323 c, g dbSNP:11902
3326 3326 a, g dbSNP:4252180
3328 3328 a, g dbSNP:115406365
3372 3372 a, g dbSNP:756263474
3385 3385 c, t dbSNP:4252199
3403 3403 a, c dbSNP:139942589
3421 3421 c, t dbSNP:183109765
3456 3456 c, t dbSNP:4252181
3474 3474 a, t dbSNP:550667817
3513 3513 a, g dbSNP:561318610
3519 3519 a, t dbSNP:530245595
3527 3527 c, t dbSNP:547111906
3531 3531 c, t dbSNP:4252182

Target ORF information:

RefSeq Version NM_000301
Organism Homo sapiens (human)
Definition Homo sapiens plasminogen (PLG), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_000301

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
ATGGAACATA AGGAAGTGGT TCTTCTACTT CTTTTATTTC TGAAATCAGG TCAAGGAGAG 
CCTCTGGATG ACTATGTGAA TACCCAGGGG GCTTCACTGT TCAGTGTCAC TAAGAAGCAG
CTGGGAGCAG GAAGTATAGA AGAATGTGCA GCAAAATGTG AGGAGGACGA AGAATTCACC
TGCAGGGCAT TCCAATATCA CAGTAAAGAG CAACAATGTG TGATAATGGC TGAAAACAGG
AAGTCCTCCA TAATCATTAG GATGAGAGAT GTAGTTTTAT TTGAAAAGAA AGTGTATCTC
TCAGAGTGCA AGACTGGGAA TGGAAAGAAC TACAGAGGGA CGATGTCCAA AACAAAAAAT
GGCATCACCT GTCAAAAATG GAGTTCCACT TCTCCCCACA GACCTAGATT CTCACCTGCT
ACACACCCCT CAGAGGGACT GGAGGAGAAC TACTGCAGGA ATCCAGACAA CGATCCGCAG
GGGCCCTGGT GCTATACTAC TGATCCAGAA AAGAGATATG ACTACTGCGA CATTCTTGAG
TGTGAAGAGG AATGTATGCA TTGCAGTGGA GAAAACTATG ACGGCAAAAT TTCCAAGACC
ATGTCTGGAC TGGAATGCCA GGCCTGGGAC TCTCAGAGCC CACACGCTCA TGGATACATT
CCTTCCAAAT TTCCAAACAA GAACCTGAAG AAGAATTACT GTCGTAACCC CGATAGGGAG
CTGCGGCCTT GGTGTTTCAC CACCGACCCC AACAAGCGCT GGGAACTTTG TGACATCCCC
CGCTGCACAA CACCTCCACC ATCTTCTGGT CCCACCTACC AGTGTCTGAA GGGAACAGGT
GAAAACTATC GCGGGAATGT GGCTGTTACC GTGTCCGGGC ACACCTGTCA GCACTGGAGT
GCACAGACCC CTCACACACA TAACAGGACA CCAGAAAACT TCCCCTGCAA AAATTTGGAT
GAAAACTACT GCCGCAATCC TGACGGAAAA AGGGCCCCAT GGTGCCATAC AACCAACAGC
CAAGTGCGGT GGGAGTACTG TAAGATACCG TCCTGTGACT CCTCCCCAGT ATCCACGGAA
CAATTGGCTC CCACAGCACC ACCTGAGCTA ACCCCTGTGG TCCAGGACTG CTACCATGGT
GATGGACAGA GCTACCGAGG CACATCCTCC ACCACCACCA CAGGAAAGAA GTGTCAGTCT
TGGTCATCTA TGACACCACA CCGGCACCAG AAGACCCCAG AAAACTACCC AAATGCTGGC
CTGACAATGA ACTACTGCAG GAATCCAGAT GCCGATAAAG GCCCCTGGTG TTTTACCACA
GACCCCAGCG TCAGGTGGGA GTACTGCAAC CTGAAAAAAT GCTCAGGAAC AGAAGCGAGT
GTTGTAGCAC CTCCGCCTGT TGTCCTGCTT CCAGATGTAG AGACTCCTTC CGAAGAAGAC
TGTATGTTTG GGAATGGGAA AGGATACCGA GGCAAGAGGG CGACCACTGT TACTGGGACG
CCATGCCAGG ACTGGGCTGC CCAGGAGCCC CATAGACACA GCATTTTCAC TCCAGAGACA
AATCCACGGG CGGGTCTGGA AAAAAATTAC TGCCGTAACC CTGATGGTGA TGTAGGTGGT
CCCTGGTGCT ACACGACAAA TCCAAGAAAA CTTTACGACT ACTGTGATGT CCCTCAGTGT
GCGGCCCCTT CATTTGATTG TGGGAAGCCT CAAGTGGAGC CGAAGAAATG TCCTGGAAGG
GTTGTAGGGG GGTGTGTGGC CCACCCACAT TCCTGGCCCT GGCAAGTCAG TCTTAGAACA
AGGTTTGGAA TGCACTTCTG TGGAGGCACC TTGATATCCC CAGAGTGGGT GTTGACTGCT
GCCCACTGCT TGGAGAAGTC CCCAAGGCCT TCATCCTACA AGGTCATCCT GGGTGCACAC
CAAGAAGTGA ATCTCGAACC GCATGTTCAG GAAATAGAAG TGTCTAGGCT GTTCTTGGAG
CCCACACGAA AAGATATTGC CTTGCTAAAG CTAAGCAGTC CTGCCGTCAT CACTGACAAA
GTAATCCCAG CTTGTCTGCC ATCCCCAAAT TATGTGGTCG CTGACCGGAC CGAATGTTTC
ATCACTGGCT GGGGAGAAAC CCAAGGTACT TTTGGAGCTG GCCTTCTCAA GGAAGCCCAG
CTCCCTGTGA TTGAGAATAA AGTGTGCAAT CGCTATGAGT TTCTGAATGG AAGAGTCCAA
TCCACCGAAC TCTGTGCTGG GCATTTGGCC GGAGGCACTG ACAGTTGCCA GGGTGACAGT
GGAGGTCCTC TGGTTTGCTT CGAGAAGGAC AAATACATTT TACAAGGAGT CACTTCTTGG
GGTCTTGGCT GTGCACGCCC CAATAAGCCT GGTGTCTATG TTCGTGTTTC AAGGTTTGTT
ACTTGGATTG AGGGAGTGAT GAGAAATAAT TAA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu22248D
Sequence Information ORF Nucleotide Sequence (Length: 411bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product plasminogen isoform 2 precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DR004070.1 and AL109933.25. Summary: The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]. Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CB116968.1, DA639760.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
ATGGAACATA AGGAAGTGGT TCTTCTACTT CTTTTATTTC TGAAATCAGG TCAAGGAGAG 
CCTCTGGATG ACTATGTGAA TACCCAGGGG GCTTCACTGT TCAGTGTCAC TAAGAAGCAG
CTGGGAGCAG GAAGTATAGA AGAATGTGCA GCAAAATGTG AGGAGGACGA AGAATTCACC
TGCAGGGCAT TCCAATATCA CAGTAAAGAG CAACAATGTG TGATAATGGC TGAAAACAGG
AAGTCCTCCA TAATCATTAG GATGAGAGAT GTAGTTTTAT TTGAAAAGAA AGTGTATCTC
TCAGAGTGCA AGACTGGGAA TGGAAAGAAC TACAGAGGGA CGATGTCCAA AACAAAAAAT
GGCATCACCT GTCAAAAATG GAGTTCCACT TCTCCCCACA GACCTAGGTTA A
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_001161810.1
CDS113..523
Misc Feature(1)53..55(+)
Misc Feature(2)224..403(+)
Misc Feature(3)224..268(+)
Misc Feature(4)344..349(+)
Misc Feature(5)416..>520(+)
Misc Feature(6)446..448(+)
Exon (1)1..161
Gene:PLG
Gene Synonym:
Exon (2)162..297
Gene:PLG
Gene Synonym:
Exon (3)298..404
Gene:PLG
Gene Synonym:
Exon (4)405..1200
Gene:PLG
Gene Synonym:
Translation
Position Chain Variation Link
30 30 g, t dbSNP:547015291
31 31 c, t dbSNP:773235483
36 36 a, g dbSNP:570081943
39 39 c, t dbSNP:532887563
40 40 a, g dbSNP:538436952
47 47 c, g dbSNP:549803884
64 64 c, t dbSNP:113759707
65 65 a, g dbSNP:745586549
74 74 c, t dbSNP:187896045
77 77 a, g dbSNP:770018389
78 78 a, g dbSNP:4252060
80 80 a, c dbSNP:749742948
81 81 a, c dbSNP:769161551
84 84 c, t dbSNP:571997762
85 85 c, t dbSNP:774345563
87 87 c, t dbSNP:761797094
90 90 -, g dbSNP:776527411
92 92 g, t dbSNP:767695607
101 101 g, t dbSNP:773284230
105 105 a, g dbSNP:374037660
112 112 a, c dbSNP:764892205
118 118 a, g dbSNP:752552388
124 124 a, g dbSNP:4252061
129 129 c, t dbSNP:764121149
131 131 g, t dbSNP:751602282
137 137 c, t dbSNP:756696418
148 148 a, g dbSNP:371469289
154 154 c, g dbSNP:750008400
162 162 a, g, t dbSNP:755657852
168 168 a, g dbSNP:753547888
173 173 c, t dbSNP:755313936
175 175 c, t dbSNP:4063623
179 179 a, g dbSNP:779290753
180 180 a, t dbSNP:748555046
181 181 c, t dbSNP:532295436
185 185 c, t dbSNP:777646481
189 189 a, t dbSNP:747105638
195 195 c, t dbSNP:771191021
196 196 a, c, g dbSNP:776968748
199 199 a, g dbSNP:768527258
203 203 c, g dbSNP:2340665
209 209 a, c, g dbSNP:774229224
211 211 c, g, t dbSNP:140570408
215 215 a, g dbSNP:760167202
217 217 c, t dbSNP:765923801
224 224 a, g dbSNP:73015965
226 226 c, g dbSNP:372999008
227 227 a, c dbSNP:138353396
235 235 g, t dbSNP:372972552
238 238 a, g dbSNP:374911072
246 246 a, g dbSNP:753109342
247 247 c, t dbSNP:1049571
249 249 c, g, t dbSNP:1049573
253 253 a, g dbSNP:778328614
259 259 c, t dbSNP:747516899
270 270 a, g dbSNP:757377776
272 272 a, g dbSNP:781448572
277 277 a, g dbSNP:746034511
278 278 a, g dbSNP:770158666
280 280 c, t dbSNP:144100362
281 281 a, g dbSNP:4252070
289 289 c, t dbSNP:771821751
311 311 c, t dbSNP:140789621
314 314 a, t dbSNP:754051719
315 315 c, g dbSNP:540661824
322 322 a, g dbSNP:777476575
333 333 a, t dbSNP:761016779
338 338 a, t dbSNP:770768604
341 341 a, g dbSNP:781084043
344 344 a, g dbSNP:745842913
349 349 c, t dbSNP:769305013
351 351 g, t dbSNP:774881372
352 352 g, t dbSNP:762605639
367 367 c, g dbSNP:768201749
376 376 a, g dbSNP:189824042
378 378 a, c, g dbSNP:143079629
385 385 a, c dbSNP:768047126
393 393 c, t dbSNP:373442935
401 401 a, c dbSNP:750930821
405 405 c, t dbSNP:777253416
408 408 a, t dbSNP:759510598
412 412 c, t dbSNP:61731705
418 418 a, c, g dbSNP:144747470
421 421 c, t dbSNP:758640124
424 424 a, g dbSNP:767238787
425 425 a, g dbSNP:750185991
426 426 c, t dbSNP:756007372
427 427 a, t dbSNP:779846532
428 428 a, g, t dbSNP:141284301
429 429 c, g dbSNP:778599053
430 430 a, g dbSNP:747756137
435 435 c, g, t dbSNP:545865924
442 442 c, t dbSNP:4757
453 453 c, t dbSNP:139357983
454 454 a, g dbSNP:776970597
459 459 a, c dbSNP:760118758
469 469 a, t dbSNP:377275189
473 473 a, g dbSNP:775557740
480 480 c, t dbSNP:370856655
507 507 a, c dbSNP:764292529
510 510 a, g dbSNP:61731706
511 511 a, c dbSNP:4252186
515 515 c, t dbSNP:199833895
517 517 c, t dbSNP:544452740
520 520 a, g dbSNP:79159046
521 521 c, t dbSNP:753682387
525 525 a, g dbSNP:754989870
531 531 c, t dbSNP:778509006
539 539 a, c dbSNP:747666681
546 546 c, t dbSNP:377592315
550 550 c, t dbSNP:758038614
556 556 c, g dbSNP:561029734
561 561 c, g dbSNP:530037780
564 564 a, g dbSNP:771159162
570 570 a, c, t dbSNP:781635106
572 572 a, g dbSNP:770286048
577 577 c, t dbSNP:546876735
585 585 a, t dbSNP:566645496
634 634 c, t dbSNP:371600373
654 654 a, g dbSNP:551866642
674 674 c, t dbSNP:776973067
679 679 c, t dbSNP:568970479
685 685 a, g dbSNP:537517059
691 691 c, t dbSNP:761940171
713 713 g, t dbSNP:4252082
719 719 a, g dbSNP:4513764
752 752 a, g dbSNP:534229030
781 781 a, c, t dbSNP:4252083
827 827 a, c dbSNP:537790926
834 834 c, g dbSNP:140952222
874 874 a, t dbSNP:4252084
884 884 c, t dbSNP:537236684
912 912 c, t dbSNP:780495516
913 913 a, g dbSNP:542313677
914 914 g, t dbSNP:181216167
934 934 g, t dbSNP:752079695
952 952 g, t dbSNP:1049638
1001 1001 c, t dbSNP:557042222
1013 1013 c, t dbSNP:4252085
1021 1021 c, t dbSNP:4252086
1030 1030 a, g dbSNP:545894744
1038 1038 a, t dbSNP:532292749
1059 1059 c, t dbSNP:113832225
1094 1094 c, t dbSNP:562118638
1100 1100 c, t dbSNP:1853018
1126 1126 a, g dbSNP:1830519
1134 1134 c, t dbSNP:144914409
1141 1141 c, t dbSNP:748706678
1146 1146 a, g dbSNP:534167106
1149 1149 c, t dbSNP:367907241
1150 1150 a, g dbSNP:184411928
1160 1160 c, g dbSNP:561954369
1167 1167 -, a dbSNP:199737099

Target ORF information:

RefSeq Version NM_001168338
Organism Homo sapiens (human)
Definition Homo sapiens plasminogen (PLG), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_001168338

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGAACATA AGGAAGTGGT TCTTCTACTT CTTTTATTTC TGAAATCAGG TCAAGGAGAG 
CCTCTGGATG ACTATGTGAA TACCCAGGGG GCTTCACTGT TCAGTGTCAC TAAGAAGCAG
CTGGGAGCAG GAAGTATAGA AGAATGTGCA GCAAAATGTG AGGAGGACGA AGAATTCACC
TGCAGGGCAT TCCAATATCA CAGTAAAGAG CAACAATGTG TGATAATGGC TGAAAACAGG
AAGTCCTCCA TAATCATTAG GATGAGAGAT GTAGTTTTAT TTGAAAAGAA AGTGTATCTC
TCAGAGTGCA AGACTGGGAA TGGAAAGAAC TACAGAGGGA CGATGTCCAA AACAAAAAAT
GGCATCACCT GTCAAAAATG GAGTTCCACT TCTCCCCACA GACCTAGGTTA A

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.