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PMS1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol PMS1
Entrez Gene ID 5378
Full Name PMS1 homolog 1, mismatch repair system component
Synonyms HNPCC3, MLH2, PMSL1, hPMS1
General protein information
Preferred Names
PMS1 protein homolog 1
Names
PMS1 protein homolog 1
mismatch repair gene PMSL1
human homolog of yeast mutL
DNA mismatch repair protein PMS1
rhabdomyosarcoma antigen MU-RMS-40.10B
rhabdomyosarcoma antigen MU-RMS-40.10E
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2q31.1

Summary This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

600258

Disorder Html: Colorectal cancer, hereditary nonpolyposis, type 3 (3)





The following PMS1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PMS1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu16502 NM_001128144 Homo sapiens PMS1 homolog 1, mismatch repair system component (PMS1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu16504 NM_001128143 Homo sapiens PMS1 homolog 1, mismatch repair system component (PMS1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu16750 NM_001289408 Homo sapiens PMS1 homolog 1, mismatch repair system component (PMS1), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu19130 NM_000534 Homo sapiens PMS1 homolog 1, mismatch repair system component (PMS1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu16750 NM_001289409 Homo sapiens PMS1 homolog 1, mismatch repair system component (PMS1), transcript variant 5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu19130 XM_005246647 PREDICTED: Homo sapiens PMS1 postmeiotic segregation increased 1 (S. cerevisiae) (PMS1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu19130 XM_011511353 PREDICTED: Homo sapiens PMS1 postmeiotic segregation increased 1 (S. cerevisiae) (PMS1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu19130 XM_011511354 PREDICTED: Homo sapiens PMS1 postmeiotic segregation increased 1 (S. cerevisiae) (PMS1), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu36363 XM_005246649 PREDICTED: Homo sapiens PMS1 postmeiotic segregation increased 1 (S. cerevisiae) (PMS1), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu59793 XM_011511355 PREDICTED: Homo sapiens PMS1 postmeiotic segregation increased 1 (S. cerevisiae) (PMS1), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu16750 XM_011511356 PREDICTED: Homo sapiens PMS1 postmeiotic segregation increased 1 (S. cerevisiae) (PMS1), transcript variant X7, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu36364 XM_006712596 PREDICTED: Homo sapiens PMS1 postmeiotic segregation increased 1 (S. cerevisiae) (PMS1), transcript variant X8, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price
OHu59794 XM_011511357 PREDICTED: Homo sapiens PMS1 postmeiotic segregation increased 1 (S. cerevisiae) (PMS1), transcript variant X9, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 Quote Price

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**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu16502
Accession Version NM_001128144.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2313bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 13-JUL-2015
Organism Homo sapiens (human)
Product PMS1 protein homolog 1 isoform c
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC347859.1, BC096330.1, AB102870.1 and BM677668.1. Summary: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (3, also known as PMS1 nirs variant 2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform c), compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC096331.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGAAACAAT TGCCTGCGGC AACAGTTCGA CTCCTTTCAA GTTCTCAGAT CATCACTTCG 
GTGGTCAGTG TTGTAAAAGA GCTTATTGAA AACTCCTTGG ATGCTGGTGC CACAAGCGTA
GATGTTAAAC TGGAGAACTA TGGATTTGAT AAAATTGAGG TGCGAGATAA CGGGGAGGGT
ATCAAGGCTG TTGATGCACC TGTAATGGCA ATGAAGTACT ACACCTCAAA AATAAATAGT
CATGAAGATC TTGAAAATTT GACAACTTAC GGTTTTCGTG GAGAAGCCTT GGGGTCAATT
TGTTGTATAG CTGAGGTTTT AATTACAACA AGAACGGCTG CTGATAATTT TAGCACCCAG
TATGTTTTAG ATGGCAGTGG CCACATACTT TCTCAGAAAC CTTCACATCT TGGTCAAGGT
ACAACTGTAA CTGCTTTAAG ATTATTTAAG AATCTACCTG TAAGAAAGCA GTTTTACTCA
ACTGCAAAAA AATGTAAAGA TGAAATAAAA AAGATCCAAG ATCTCCTCAT GAGCTTTGGT
ATCCTTAAAC CTGACTTAAG GATTGTCTTT GTACATAACA AGGCAGTTAT TTGGCAGAAA
AGCAGAGTAT CAGATCACAA GATGGCTCTC ATGTCAGTTC TGGGGACTGC TGTTATGAAC
AATATGGAAT CCTTTCAGTA CCACTCTGAA GAATCTCAGA TTTATCTCAG TGGATTTCTT
CCAAAGTGTG ATGCAGACCA CTCTTTCACT AGTCTTTCAA CACCAGAAAG AAGTTTCATC
TTCATAAACA GTCGACCAGT ACATCAAAAA GATATCTTAA AGTTAATCCG ACATCATTAC
AATCTGAAAT GCCTAAAGGA ATCTACTCGT TTGTATCCTG TTTTCTTTCT GAAAATCGAT
GTTCCTACAG CTGATGTTGA TGTAAATTTA ACACCAGATA AAAGCCAAGT ATTATTACAA
AATAAGGAAT CTGTTTTAAT TGCTCTTGAA AATCTGATGA CGACTTGTTA TGGACCATTA
CCTAGTACAA ATTCTTATGA AAATAATAAA ACAGATGTTT CCGCAGCTGA CATCGTTCTT
AGTAAAACAG CAGAAACAGA TGTGCTTTTT AATAAAGTGG AATCATCTGG AAAGAATTAT
TCAAATGTTG ATACTTCAGT CATTCCATTC CAAAATGATA TGCATAATGA TGAATCTGGA
AAAAACACTG ATGATTGTTT AAATCACCAG ATAAGTATTG GTGACTTTGG TTATGGTCAT
TGTAGTAGTG AAATTTCTAA CATTGATAAA AACACTAAGA ATGCATTTCA GGACATTTCA
ATGAGTAATG TATCATGGGA GAACTCTCAG ACGGAATATA GTAAAACTTG TTTTATAAGT
TCCGTTAAGC ACACCCAGTC AGAAAATGGC AATAAAGACC ATATAGATGA GAGTGGGGAA
AATGAGGAAG AAGCAGGTCT TGAAAACTCT TCGGAAATTT CTGCAGATGA GTGGAGCAGG
GGAAATATAC TTAAAAATTC AGTGGGAGAG AATATTGAAC CTGTGAAAAT TTTAGTGCCT
GAAAAAAGTT TACCATGTAA AGTAAGTAAT AATAATTATC CAATCCCTGA ACAAATGAAT
CTTAATGAAG ATTCATGTAA CAAAAAATCA AATGTAATAG ATAATAAATC TGGAAAAGTT
ACAGCTTATG ATTTACTTAG CAATCGAGTA ATCAAGAAAC CCATGTCAGC AAGTGCTCTT
TTTGTTCAAG ATCATCGTCC TCAGTTTCTC ATAGAAAATC CTAAGACTAG TTTAGAGGAT
GCAACACTAC AAATTGAAGA ACTGTGGAAG ACATTGAGTG AAGAGGAAAA ACTGAATCTT
TTTAATGGAT CTCATTATTT AGACGTTTTA TATAAAATGA CAGCAGATGA CCAAAGATAC
AGTGGATCAA CTTACCTGTC TGATCCTCGT CTTACAGCGA ATGGTTTCAA GATAAAATTG
ATACCAGGAG TTTCAATTAC TGAAAATTAC TTGGAAATAG AAGGAATGGC TAATTGTCTC
CCATTCTATG GAGTAGCAGA TTTAAAAGAA ATTCTTAATG CTATATTAAA CAGAAATGCA
AAGGAAGTTT ATGAATGTAG ACCTCGCAAA GTGATAAGTT ATTTAGAGGG AGAAGCAGTG
CGTCTATCCA GACAATTACC CATGTACTTA TCAAAAGAGG ACATCCAAGA CATTATCTAC
AGAATGAAGC ACCAGTTTGG AAATGAAATT AAAGAGTGTG TTCATGGTCG CCCATTTTTT
CATCATTTAA CCTATCTTCC AGAAACTACA TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001121616.1
CDS530..2842
Misc Feature(1)366..366(+)
Misc Feature(2)401..401(+)
Misc Feature(3)412..412(+)
Misc Feature(4)476..476(+)
Misc Feature(5)500..502(+)
Misc Feature(6)530..1483(+)
Misc Feature(7)596..>832(+)
Misc Feature(8)608..820(+)
Misc Feature(9)620..622(+)
Misc Feature(10)701..817(+)
Misc Feature(11)1142..1543(+)
Misc Feature(12)1469..1471(+)
Misc Feature(13)2243..>2380(+)
Misc Feature(14)2246..2356(+)
Exon (1)1..509
Gene:PMS1
Gene Synonym:
Exon (2)510..661
Gene:PMS1
Gene Synonym:
Exon (3)662..844
Gene:PMS1
Gene Synonym:
Exon (4)845..947
Gene:PMS1
Gene Synonym:
Exon (5)948..1111
Gene:PMS1
Gene Synonym:
Exon (6)1112..1228
Gene:PMS1
Gene Synonym:
Exon (7)1229..1351
Gene:PMS1
Gene Synonym:
Exon (8)1352..1495
Gene:PMS1
Gene Synonym:
Exon (9)1496..2385
Gene:PMS1
Gene Synonym:
Exon (10)2386..2516
Gene:PMS1
Gene Synonym:
Exon (11)2517..2677
Gene:PMS1
Gene Synonym:
Exon (12)2678..3035
Gene:PMS1
Gene Synonym:
Translation
Position Chain Variation Link
20 20 a, g dbSNP:189547607
22 22 a, g dbSNP:536962444
23 23 c, t dbSNP:554655433
34 34 c, g dbSNP:750021361
41 41 a, g dbSNP:576428024
49 49 a, g dbSNP:5742927
53 53 c, g dbSNP:565412237
60 60 c, t dbSNP:757816314
70 70 c, t dbSNP:577428807
74 74 c, g dbSNP:11550049
89 89 g, t dbSNP:541196484
96 96 c, t dbSNP:559590295
137 137 a, c, g dbSNP:369675358
139 139 a, c dbSNP:529904737
175 175 a, g dbSNP:548513402
187 187 a, g dbSNP:5742928
194 194 c, t dbSNP:372712876
200 200 g, t dbSNP:758067747
207 207 c, t dbSNP:777624544
228 228 c, t dbSNP:5742929
232 232 g, t dbSNP:746616111
246 246 a, c dbSNP:551774070
250 250 a, c dbSNP:5742930
255 255 c, t dbSNP:5742931
256 256 a, t dbSNP:534415170
264 264 a, g dbSNP:547545719
271 271 a, c dbSNP:566304104
290 290 a, c dbSNP:536540364
296 296 c, t dbSNP:756536859
298 298 g, t dbSNP:745440258
350 350 c, g dbSNP:555270776
366 366 a, g dbSNP:777937194
371 371 c, t dbSNP:576342227
374 374 a, g dbSNP:147002700
380 380 c, t dbSNP:749530064
386 386 a, c, g dbSNP:375594683
409 409 -, gggtgc dbSNP:766501073
410 410 a, g dbSNP:757537327
422 422 c, g dbSNP:779071853
424 424 a, g dbSNP:556452424
427 427 c, t dbSNP:745993205
430 430 g, t dbSNP:5742932
431 431 g, t dbSNP:577363454
442 442 a, g dbSNP:541545004
446 446 c, g, t dbSNP:374103918
454 454 a, g dbSNP:559588204
483 483 a, g dbSNP:574605931
504 504 a, c dbSNP:771993432
506 506 c, g dbSNP:5742933
514 514 c, t dbSNP:757794123
515 515 c, t dbSNP:781605412
525 525 c, t dbSNP:570050132
526 526 a, g dbSNP:754586160
538 538 a, g dbSNP:373031044
540 540 c, t dbSNP:201944922
544 544 c, t dbSNP:778660303
546 546 c, t dbSNP:747835603
547 547 a, g dbSNP:771930754
551 551 a, g dbSNP:777641087
558 558 a, g dbSNP:370084230
561 561 c, t dbSNP:770894099
562 562 c, t dbSNP:762260830
563 563 a, c, t dbSNP:374261058
569 569 a, g dbSNP:775649361
570 570 a, g dbSNP:763166242
574 574 a, t dbSNP:377616727
576 576 a, g dbSNP:570876790
578 578 a, g dbSNP:151231718
585 585 c, g dbSNP:534847551
588 588 c, t dbSNP:768047966
589 589 g, t dbSNP:750916185
592 592 g, t dbSNP:754498304
599 599 a, g dbSNP:553130827
608 608 c, g dbSNP:5742973
635 635 a, g dbSNP:781053212
642 642 -, caagcg dbSNP:761879899
643 643 a, t dbSNP:758112220
644 644 a, g dbSNP:113193813
646 646 c, t dbSNP:777358818
647 647 a, g dbSNP:746784366
650 650 c, g dbSNP:757048301
651 651 a, c, g dbSNP:545600556
655 655 g, t dbSNP:769797470
669 669 a, g dbSNP:756031414
670 670 c, t dbSNP:5742980
681 681 a, c dbSNP:370668897
692 692 c, t dbSNP:375147123
696 696 a, g dbSNP:377024581
700 700 -, g dbSNP:765360578
700 700 c, t dbSNP:756254396
701 701 a, g dbSNP:772427166
702 702 a, g dbSNP:773700771
703 703 gg, ta dbSNP:587778608
703 703 g, t dbSNP:143323454
704 704 a, g dbSNP:143265397
728 728 c, t dbSNP:777322683
737 737 g, t dbSNP:753676547
740 740 a, g dbSNP:763541657
751 751 c, t dbSNP:751153318
753 753 c, t dbSNP:61756360
754 754 c, g dbSNP:201065617
759 759 -, aaat dbSNP:773464464
766 766 c, t dbSNP:750214766
771 771 a, g dbSNP:755941492
772 772 c, t dbSNP:150543935
786 786 a, t dbSNP:779918450
796 796 g, t dbSNP:753750267
797 797 -, a dbSNP:753745201
799 799 a, c, t dbSNP:149723996
800 800 a, g dbSNP:370300640
806 806 c, t dbSNP:772181508
807 807 a, c, g dbSNP:778185859
816 816 a, c, g, t dbSNP:139414606
816 816 -, c dbSNP:763126626
823 823 a, g dbSNP:541076815
827 827 a, g dbSNP:768152350
831 831 a, g dbSNP:773719324
834 834 a, g dbSNP:761453284
839 839 a, c, g dbSNP:200395679
845 845 c, g dbSNP:766079191
856 856 a, g dbSNP:146515816
858 858 c, g dbSNP:372752293
863 863 a, g dbSNP:765068532
864 864 c, t dbSNP:576285843
865 865 a, g dbSNP:543376612
866 866 g, t dbSNP:764270787
874 874 c, t dbSNP:2066457
883 883 c, t dbSNP:757537798
885 885 c, t dbSNP:781542667
899 899 c, g dbSNP:746186468
900 900 a, g dbSNP:756549435
903 903 a, g dbSNP:780386003
911 911 c, t dbSNP:576726933
914 914 a, g dbSNP:771514571
922 922 c, t dbSNP:772697027
929 929 a, c, t dbSNP:746592348
930 930 c, t dbSNP:776398978
932 932 a, t dbSNP:759206167
950 950 a, g dbSNP:773337973
958 958 a, g dbSNP:150245286
961 961 c, t dbSNP:370516860
963 963 c, g dbSNP:766604209
969 969 a, g dbSNP:113137368
981 981 a, g dbSNP:754084013
988 988 c, t dbSNP:759858356
1003 1003 a, t dbSNP:369474547
1005 1005 a, t dbSNP:765594171
1008 1008 c, t dbSNP:550220809
1014 1014 -, a dbSNP:779955300
1015 1015 -, a dbSNP:587778609
1018 1018 -, aaaatgt dbSNP:746998919
1025 1025 a, g dbSNP:758921945
1029 1029 a, g dbSNP:200244068
1052 1052 c, t dbSNP:749915619
1054 1054 c, t dbSNP:532912232
1059 1059 c, t dbSNP:755627056
1063 1063 a, c, t dbSNP:779802611
1070 1070 a, g dbSNP:768513050
1080 1080 a, c dbSNP:778838293
1084 1084 c, t dbSNP:73979090
1089 1089 a, g dbSNP:772016473
1098 1098 c, t dbSNP:773075006
1100 1100 g, t dbSNP:760761733
1103 1103 c, t dbSNP:771034057
1104 1104 a, g dbSNP:587778610
1107 1107 a, g dbSNP:776771191
1119 1119 a, t dbSNP:185306467
1123 1123 g, t dbSNP:143010673
1125 1125 a, c dbSNP:774854343
1131 1131 g, t dbSNP:762396678
1132 1132 c, t dbSNP:141178436
1134 1134 a, g dbSNP:2066459
1136 1136 -, t dbSNP:773199906
1137 1137 c, t dbSNP:754586112
1142 1142 c, g dbSNP:764936813
1143 1143 a, t dbSNP:752326070
1145 1145 c, g, t dbSNP:758149651
1147 1147 -, c dbSNP:763190120
1155 1155 c, t dbSNP:746884261
1157 1157 c, g dbSNP:757185669
1161 1161 c, t dbSNP:781151298
1171 1171 a, g dbSNP:745928666
1185 1185 c, t dbSNP:769887269
1194 1194 c, t dbSNP:775742142
1207 1207 c, g dbSNP:749477891
1226 1226 c, t dbSNP:121434628
1252 1252 a, g dbSNP:779243339
1255 1255 a, g dbSNP:56144843
1260 1260 a, t dbSNP:772593735
1265 1265 g, t dbSNP:75465207
1269 1269 a, g dbSNP:773786180
1292 1292 c, t dbSNP:769264049
1296 1296 a, g dbSNP:771521891
1298 1298 a, g dbSNP:774862999
1309 1309 c, t dbSNP:762568785
1315 1315 a, g dbSNP:763634931
1318 1318 c, t dbSNP:756974504
1319 1319 a, t dbSNP:751238299
1322 1322 c, t dbSNP:761558970
1341 1341 -, a dbSNP:774706986
1343 1343 a, g dbSNP:375164425
1344 1344 c, t dbSNP:767306276
1347 1347 c, t dbSNP:750303019
1348 1348 a, c dbSNP:755991524
1350 1350 a, c dbSNP:780079764
1355 1355 a, c dbSNP:777247528
1356 1356 c, t dbSNP:748700549
1358 1358 c, t dbSNP:768246348
1359 1359 a, g dbSNP:773928881
1365 1365 a, g dbSNP:761470579
1369 1369 c, g dbSNP:767216229
1391 1391 c, t dbSNP:772959693
1392 1392 c, t dbSNP:760566355
1394 1394 a, g dbSNP:766177870
1397 1397 c, t dbSNP:753843878
1398 1398 a, g dbSNP:183717609
1418 1418 c, g dbSNP:146040262
1424 1424 a, g dbSNP:752879186
1426 1426 c, t dbSNP:149988991
1428 1428 a, c dbSNP:574137844
1436 1436 a, g dbSNP:747316625
1437 1437 c, t dbSNP:757665441
1465 1465 a, g dbSNP:781513402
1469 1469 a, g dbSNP:148745528
1484 1484 a, t dbSNP:767995024
1487 1487 c, t dbSNP:773838917
1491 1491 a, g dbSNP:147901996
1492 1492 c, t dbSNP:202008207
1493 1493 a, g dbSNP:772872765
1496 1496 g, t dbSNP:777221902
1497 1497 a, g dbSNP:746684224
1514 1514 c, g, t dbSNP:770544182
1517 1517 c, g dbSNP:759285880
1528 1528 -, gac dbSNP:750135409
1530 1530 c, t dbSNP:147084726
1531 1531 a, g dbSNP:775595671
1532 1532 a, g dbSNP:763089248
1536 1536 a, g dbSNP:764276785
1540 1540 c, t dbSNP:751675535
1546 1546 a, g dbSNP:569336571
1547 1547 c, t dbSNP:762083170
1555 1555 c, t dbSNP:767698592
1556 1556 a, g dbSNP:750770322
1566 1566 a, g dbSNP:540051947
1567 1567 c, t dbSNP:780499163
1573 1573 a, taat dbSNP:386653706
1582 1582 a, g dbSNP:754345445
1583 1583 a, g dbSNP:757843914
1586 1586 a, g dbSNP:777321010
1589 1589 a, t dbSNP:746564566
1591 1591 c, t dbSNP:770583200
1592 1592 a, g dbSNP:141084536
1603 1603 c, t dbSNP:745613341
1604 1604 a, g dbSNP:369839744
1620 1620 c, t dbSNP:755937219
1647 1647 c, t dbSNP:199659366
1655 1655 -, c dbSNP:34800695
1658 1658 -, g dbSNP:758168664
1659 1659 c, g dbSNP:775503944
1672 1672 a, g dbSNP:763001065
1683 1683 c, g dbSNP:768772690
1687 1687 a, g dbSNP:779635858
1691 1691 a, c dbSNP:774486487
1696 1696 a, g dbSNP:761838436
1699 1699 c, g dbSNP:767757337
1701 1701 a, g dbSNP:750642262
1706 1706 g, t dbSNP:760960503
1707 1707 a, t dbSNP:766742199
1708 1708 c, t dbSNP:754255687
1710 1710 c, t dbSNP:1145231
1713 1713 a, g dbSNP:145375126
1720 1720 g, t dbSNP:567192785
1727 1727 -, g dbSNP:779867285
1728 1728 -, a dbSNP:746911496
1730 1730 a, t dbSNP:756743623
1738 1738 -, tga dbSNP:768607381
1751 1751 a, c dbSNP:768147034
1754 1754 -, cac dbSNP:777855415
1760 1760 a, g dbSNP:780862528
1770 1770 a, g dbSNP:745523368
1783 1783 c, t dbSNP:755918305
1791 1791 g, t dbSNP:142577664
1808 1808 a, g dbSNP:373271688
1810 1810 c, t dbSNP:749164046
1811 1811 a, g dbSNP:768607896
1821 1821 a, g dbSNP:774205801
1827 1827 a, c, g dbSNP:148690800
1829 1829 a, g dbSNP:534500725
1834 1834 a, g dbSNP:760872306
1840 1840 a, c, g dbSNP:55726197
1841 1841 c, g dbSNP:776947297
1850 1850 a, g dbSNP:759938479
1855 1855 g, t dbSNP:765723624
1857 1857 a, g dbSNP:200407029
1858 1858 c, t dbSNP:189863121
1858 1858 -, t dbSNP:763044411
1859 1859 g, t dbSNP:369312075
1861 1861 a, c, g dbSNP:534243480
1862 1862 c, t dbSNP:373224158
1877 1877 c, t dbSNP:779894503
1878 1878 a, g dbSNP:56305733
1881 1881 c, t dbSNP:181493700
1882 1882 a, g dbSNP:754752991
1886 1886 a, t dbSNP:778843582
1892 1892 a, g dbSNP:748046504
1905 1905 -, a dbSNP:749329798
1909 1909 g, t dbSNP:768758116
1909 1909 -, t dbSNP:771104806
1912 1912 c, t dbSNP:747621119
1915 1915 a, t dbSNP:773272437
1923 1923 c, t dbSNP:747129479
1936 1936 a, t dbSNP:144599126
1947 1947 a, t dbSNP:776857506
1948 1948 c, g dbSNP:759908270
1951 1951 c, t dbSNP:765529423
1953 1953 c, t dbSNP:371392948
1956 1956 a, g dbSNP:571235425
1958 1958 g, t dbSNP:764765315
1964 1964 a, g dbSNP:749923368
1965 1965 c, g dbSNP:587778612
1981 1981 a, g dbSNP:766081471
2001 2001 c, t dbSNP:753545002
2002 2002 a, g dbSNP:754744032
2006 2006 a, c dbSNP:778557193
2010 2010 c, t dbSNP:752602525
2012 2012 a, g dbSNP:758235016
2015 2015 a, g dbSNP:777734081
2016 2016 a, g dbSNP:375640863
2017 2017 c, t dbSNP:747037734
2025 2025 a, g dbSNP:775222893
2030 2030 a, g dbSNP:1145232
2033 2033 a, t dbSNP:781328782
2036 2036 a, g dbSNP:746096258
2037 2037 a, c, t dbSNP:770115265
2069 2069 c, g dbSNP:368282144
2071 2071 c, t dbSNP:763416734
2100 2100 c, g, t dbSNP:560096410
2105 2105 c, t dbSNP:760223545
2115 2115 a, g dbSNP:56064816
2118 2118 a, g dbSNP:753446372
2128 2128 g, t dbSNP:759105195
2135 2135 c, t dbSNP:201236867
2138 2138 a, g dbSNP:151325573
2150 2150 c, t dbSNP:759894015
2152 2152 g, t dbSNP:113372387
2155 2155 c, t dbSNP:777644154
2159 2159 g, t dbSNP:751506189
2163 2163 a, c dbSNP:757273212
2166 2166 a, g dbSNP:531239757
2170 2170 -, a dbSNP:774420632
2172 2172 a, g dbSNP:61736576
2173 2173 a, g dbSNP:769876795
2188 2188 a, c dbSNP:780372372
2190 2190 a, g dbSNP:749568233
2207 2207 -, g dbSNP:759884049
2213 2213 g, t dbSNP:189785572
2214 2214 a, c, t dbSNP:774939385
2219 2219 a, g dbSNP:531589926
2221 2221 c, t dbSNP:775824945
2225 2225 c, g dbSNP:140854388
2234 2234 c, t dbSNP:201194903
2235 2235 a, g dbSNP:138610933
2237 2237 a, g dbSNP:775236748
2243 2243 a, g dbSNP:762666544
2262 2262 a, g dbSNP:768653497
2271 2271 -, ttg dbSNP:772532489
2273 2273 a, g dbSNP:74512161
2285 2285 a, c, t dbSNP:566975683
2286 2286 a, g dbSNP:750449314
2298 2298 g, t dbSNP:756240681
2299 2299 c, t dbSNP:780100887
2301 2301 c, t dbSNP:749530914
2311 2311 g, t dbSNP:755308444
2320 2320 g, t dbSNP:139552807
2321 2321 a, t dbSNP:748563735
2323 2323 a, c dbSNP:772681534
2327 2327 a, g dbSNP:773787379
2328 2328 a, g dbSNP:745326955
2329 2329 c, t dbSNP:769347993
2330 2330 a, g dbSNP:147450758
2333 2333 a, g dbSNP:762582922
2359 2359 c, g dbSNP:751603605
2362 2362 a, g dbSNP:550510753
2363 2363 c, t dbSNP:763806939
2374 2374 a, c, g dbSNP:774104441
2377 2377 a, g dbSNP:767309798
2382 2382 g, t dbSNP:145406444
2394 2394 a, g dbSNP:55680602
2396 2396 c, g dbSNP:777821897
2401 2401 c, t dbSNP:201324347
2406 2406 a, g dbSNP:553828991
2412 2412 a, t dbSNP:757396542
2413 2413 c, t dbSNP:762377532
2414 2414 a, g dbSNP:781501975
2420 2420 c, g, t dbSNP:1145234
2421 2421 a, g dbSNP:770203209
2423 2423 a, t dbSNP:776086491
2428 2428 g, t dbSNP:749800455
2431 2431 a, g dbSNP:769354925
2443 2443 a, g dbSNP:150865251
2450 2450 a, c dbSNP:760284046
2460 2460 c, g dbSNP:55859858
2463 2463 a, t dbSNP:200919195
2465 2465 c, g dbSNP:759191350
2477 2477 c, t dbSNP:371745827
2478 2478 a, g, t dbSNP:375020232
2483 2483 a, g dbSNP:200172149
2484 2484 c, g dbSNP:369226504
2485 2485 a, g dbSNP:777704189
2487 2487 c, t dbSNP:139826569
2493 2493 a, g, t dbSNP:781206054
2503 2503 a, g dbSNP:756353601
2513 2513 a, c dbSNP:587778611
2536 2536 c, t dbSNP:576339546
2539 2539 c, g dbSNP:756377066
2543 2543 g, t dbSNP:780475445
2561 2561 a, g dbSNP:369909997
2565 2565 a, g dbSNP:755396415
2577 2577 a, g dbSNP:779501477
2582 2582 -, g dbSNP:772445011
2583 2583 c, t dbSNP:199892342
2584 2584 a, g dbSNP:772517576
2598 2598 a, c dbSNP:145521752
2601 2601 c, t dbSNP:745418589
2607 2607 a, c, g, t dbSNP:56309301
2613 2613 c, t dbSNP:762670803
2619 2619 a, g dbSNP:768453779
2630 2630 a, g dbSNP:774072907
2634 2634 a, g dbSNP:761809273
2638 2638 a, t dbSNP:767398078
2646 2646 a, g dbSNP:564962629
2654 2654 c, t dbSNP:143554211
2655 2655 a, g, t dbSNP:760863069
2655 2655 -, g dbSNP:775939224
2687 2687 a, g dbSNP:374222815
2690 2690 -, a dbSNP:769123166
2690 2690 c, t dbSNP:142159998
2691 2691 -, acgc dbSNP:776982819
2691 2691 a, g dbSNP:377603311
2692 2692 a, t dbSNP:748840882
2699 2699 a, t dbSNP:754639850
2704 2704 a, g dbSNP:61748257
2705 2705 c, t dbSNP:370611400
2708 2708 c, g dbSNP:374879205
2711 2711 a, t dbSNP:537745271
2714 2714 -, tact dbSNP:762425602
2716 2716 -, tta dbSNP:764615055
2727 2727 a, g dbSNP:746934898
2732 2732 a, t dbSNP:771027683
2736 2736 a, g dbSNP:776829529
2741 2741 a, g dbSNP:759710002
2748 2748 a, g dbSNP:765457307
2753 2753 a, c dbSNP:775577121
2759 2759 c, t dbSNP:763320793
2762 2762 c, g dbSNP:775695414
2778 2778 c, t dbSNP:764353574
2795 2795 a, g dbSNP:751989008
2797 2797 c, t dbSNP:757731143
2798 2798 c, t dbSNP:145103030
2799 2799 a, g, t dbSNP:147566508
2812 2812 a, t dbSNP:778563772
2819 2819 a, g dbSNP:138906915
2822 2822 c, t dbSNP:758133616
2823 2823 a, g dbSNP:111254723
2844 2844 a, t dbSNP:746846733
2852 2852 a, t dbSNP:5743199
2855 2855 -, aag dbSNP:772733884
2857 2857 g, t dbSNP:768386630
2878 2878 g, t dbSNP:745892695
2895 2895 c, t dbSNP:774172390
2897 2897 a, g dbSNP:764216417
2902 2902 a, g dbSNP:553749816
2919 2919 -, t dbSNP:753967087
2929 2929 a, g dbSNP:761210807
2954 2954 c, t dbSNP:572013326
2980 2980 c, t dbSNP:112239654
3009 3009 c, t dbSNP:542744208
3024 3024 a, g dbSNP:562248054
3031 3031 a, c dbSNP:767117479

Target ORF information:

RefSeq Version NM_001128144
Organism Homo sapiens (human)
Definition Homo sapiens PMS1 homolog 1, mismatch repair system component (PMS1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001128144

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
ATGAAACAAT TGCCTGCGGC AACAGTTCGA CTCCTTTCAA GTTCTCAGAT CATCACTTCG 
GTGGTCAGTG TTGTAAAAGA GCTTATTGAA AACTCCTTGG ATGCTGGTGC CACAAGCGTA
GATGTTAAAC TGGAGAACTA TGGATTTGAT AAAATTGAGG TGCGAGATAA CGGGGAGGGT
ATCAAGGCTG TTGATGCACC TGTAATGGCA ATGAAGTACT ACACCTCAAA AATAAATAGT
CATGAAGATC TTGAAAATTT GACAACTTAC GGTTTTCGTG GAGAAGCCTT GGGGTCAATT
TGTTGTATAG CTGAGGTTTT AATTACAACA AGAACGGCTG CTGATAATTT TAGCACCCAG
TATGTTTTAG ATGGCAGTGG CCACATACTT TCTCAGAAAC CTTCACATCT TGGTCAAGGT
ACAACTGTAA CTGCTTTAAG ATTATTTAAG AATCTACCTG TAAGAAAGCA GTTTTACTCA
ACTGCAAAAA AATGTAAAGA TGAAATAAAA AAGATCCAAG ATCTCCTCAT GAGCTTTGGT
ATCCTTAAAC CTGACTTAAG GATTGTCTTT GTACATAACA AGGCAGTTAT TTGGCAGAAA
AGCAGAGTAT CAGATCACAA GATGGCTCTC ATGTCAGTTC TGGGGACTGC TGTTATGAAC
AATATGGAAT CCTTTCAGTA CCACTCTGAA GAATCTCAGA TTTATCTCAG TGGATTTCTT
CCAAAGTGTG ATGCAGACCA CTCTTTCACT AGTCTTTCAA CACCAGAAAG AAGTTTCATC
TTCATAAACA GTCGACCAGT ACATCAAAAA GATATCTTAA AGTTAATCCG ACATCATTAC
AATCTGAAAT GCCTAAAGGA ATCTACTCGT TTGTATCCTG TTTTCTTTCT GAAAATCGAT
GTTCCTACAG CTGATGTTGA TGTAAATTTA ACACCAGATA AAAGCCAAGT ATTATTACAA
AATAAGGAAT CTGTTTTAAT TGCTCTTGAA AATCTGATGA CGACTTGTTA TGGACCATTA
CCTAGTACAA ATTCTTATGA AAATAATAAA ACAGATGTTT CCGCAGCTGA CATCGTTCTT
AGTAAAACAG CAGAAACAGA TGTGCTTTTT AATAAAGTGG AATCATCTGG AAAGAATTAT
TCAAATGTTG ATACTTCAGT CATTCCATTC CAAAATGATA TGCATAATGA TGAATCTGGA
AAAAACACTG ATGATTGTTT AAATCACCAG ATAAGTATTG GTGACTTTGG TTATGGTCAT
TGTAGTAGTG AAATTTCTAA CATTGATAAA AACACTAAGA ATGCATTTCA GGACATTTCA
ATGAGTAATG TATCATGGGA GAACTCTCAG ACGGAATATA GTAAAACTTG TTTTATAAGT
TCCGTTAAGC ACACCCAGTC AGAAAATGGC AATAAAGACC ATATAGATGA GAGTGGGGAA
AATGAGGAAG AAGCAGGTCT TGAAAACTCT TCGGAAATTT CTGCAGATGA GTGGAGCAGG
GGAAATATAC TTAAAAATTC AGTGGGAGAG AATATTGAAC CTGTGAAAAT TTTAGTGCCT
GAAAAAAGTT TACCATGTAA AGTAAGTAAT AATAATTATC CAATCCCTGA ACAAATGAAT
CTTAATGAAG ATTCATGTAA CAAAAAATCA AATGTAATAG ATAATAAATC TGGAAAAGTT
ACAGCTTATG ATTTACTTAG CAATCGAGTA ATCAAGAAAC CCATGTCAGC AAGTGCTCTT
TTTGTTCAAG ATCATCGTCC TCAGTTTCTC ATAGAAAATC CTAAGACTAG TTTAGAGGAT
GCAACACTAC AAATTGAAGA ACTGTGGAAG ACATTGAGTG AAGAGGAAAA ACTGAATCTT
TTTAATGGAT CTCATTATTT AGACGTTTTA TATAAAATGA CAGCAGATGA CCAAAGATAC
AGTGGATCAA CTTACCTGTC TGATCCTCGT CTTACAGCGA ATGGTTTCAA GATAAAATTG
ATACCAGGAG TTTCAATTAC TGAAAATTAC TTGGAAATAG AAGGAATGGC TAATTGTCTC
CCATTCTATG GAGTAGCAGA TTTAAAAGAA ATTCTTAATG CTATATTAAA CAGAAATGCA
AAGGAAGTTT ATGAATGTAG ACCTCGCAAA GTGATAAGTT ATTTAGAGGG AGAAGCAGTG
CGTCTATCCA GACAATTACC CATGTACTTA TCAAAAGAGG ACATCCAAGA CATTATCTAC
AGAATGAAGC ACCAGTTTGG AAATGAAATT AAAGAGTGTG TTCATGGTCG CCCATTTTTT
CATCATTTAA CCTATCTTCC AGAAACTACA TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16504
Accession Version NM_001128143.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2682bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 13-JUL-2015
Organism Homo sapiens (human)
Product PMS1 protein homolog 1 isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC347859.1, AB102875.1 and BM677668.1. Summary: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (2, also known as PMS1 nirs variant 7) lacks an alternate in-frame exon in the mid-coding region, compared to variant 1, resulting in a shorter protein (isoform b), compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AB102875.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
ATGAAACAAT TGCCTGCGGC AACAGTTCGA CTCCTTTCAA GTTCTCAGAT CATCACTTCG 
GTGGTCAGTG TTGTAAAAGA GCTTATTGAA AACTCCTTGG ATGCTGGTGC CACAAGCGTA
GATGTTAAAC TGGAGAACTA TGGATTTGAT AAAATTGAGG TGCGAGATAA CGGGGAGGGT
ATCAAGGCTG TTGATGCACC TGTAATGGCA ATGAAGTACT ACACCTCAAA AATAAATAGT
CATGAAGATC TTGAAAATTT GACAACTTAC GGTTTTCGTG GAGAAGCCTT GGGGTCAATT
TGTTGTATAG CTGAGGTTTT AATTACAACA AGAACGGCTG CTGATAATTT TAGCACCCAG
TATGTTTTAG ATGGCAGTGG CCACATACTT TCTCAGAAAC CTTCACATCT TGGTCAAGGT
ACAACTGTAA CTGCTTTAAG ATTATTTAAG AATCTACCTG TAAGAAAGCA GTTTTACTCA
ACTGCAAAAA AATGTAAAGA TGAAATAAAA AAGATCCAAG ATCTCCTCAT GAGCTTTGGT
ATCCTTAAAC CTGACTTAAG GATTGTCTTT GTACATAACA AGATTTATCT CAGTGGATTT
CTTCCAAAGT GTGATGCAGA CCACTCTTTC ACTAGTCTTT CAACACCAGA AAGAAGTTTC
ATCTTCATAA ACAGTCGACC AGTACATCAA AAAGATATCT TAAAGTTAAT CCGACATCAT
TACAATCTGA AATGCCTAAA GGAATCTACT CGTTTGTATC CTGTTTTCTT TCTGAAAATC
GATGTTCCTA CAGCTGATGT TGATGTAAAT TTAACACCAG ATAAAAGCCA AGTATTATTA
CAAAATAAGG AATCTGTTTT AATTGCTCTT GAAAATCTGA TGACGACTTG TTATGGACCA
TTACCTAGTA CAAATTCTTA TGAAAATAAT AAAACAGATG TTTCCGCAGC TGACATCGTT
CTTAGTAAAA CAGCAGAAAC AGATGTGCTT TTTAATAAAG TGGAATCATC TGGAAAGAAT
TATTCAAATG TTGATACTTC AGTCATTCCA TTCCAAAATG ATATGCATAA TGATGAATCT
GGAAAAAACA CTGATGATTG TTTAAATCAC CAGATAAGTA TTGGTGACTT TGGTTATGGT
CATTGTAGTA GTGAAATTTC TAACATTGAT AAAAACACTA AGAATGCATT TCAGGACATT
TCAATGAGTA ATGTATCATG GGAGAACTCT CAGACGGAAT ATAGTAAAAC TTGTTTTATA
AGTTCCGTTA AGCACACCCA GTCAGAAAAT GGCAATAAAG ACCATATAGA TGAGAGTGGG
GAAAATGAGG AAGAAGCAGG TCTTGAAAAC TCTTCGGAAA TTTCTGCAGA TGAGTGGAGC
AGGGGAAATA TACTTAAAAA TTCAGTGGGA GAGAATATTG AACCTGTGAA AATTTTAGTG
CCTGAAAAAA GTTTACCATG TAAAGTAAGT AATAATAATT ATCCAATCCC TGAACAAATG
AATCTTAATG AAGATTCATG TAACAAAAAA TCAAATGTAA TAGATAATAA ATCTGGAAAA
GTTACAGCTT ATGATTTACT TAGCAATCGA GTAATCAAGA AACCCATGTC AGCAAGTGCT
CTTTTTGTTC AAGATCATCG TCCTCAGTTT CTCATAGAAA ATCCTAAGAC TAGTTTAGAG
GATGCAACAC TACAAATTGA AGAACTGTGG AAGACATTGA GTGAAGAGGA AAAACTGAAA
TATGAAGAGA AGGCTACTAA AGACTTGGAA CGATACAATA GTCAAATGAA GAGAGCCATT
GAACAGGAGT CACAAATGTC ACTAAAAGAT GGCAGAAAAA AGATAAAACC CACCAGCGCA
TGGAATTTGG CCCAGAAGCA CAAGTTAAAA ACCTCATTAT CTAATCAACC AAAACTTGAT
GAACTCCTTC AGTCCCAAAT TGAAAAAAGA AGGAGTCAAA ATATTAAAAT GGTACAGATC
CCCTTTTCTA TGAAAAACTT AAAAATAAAT TTTAAGAAAC AAAACAAAGT TGACTTAGAA
GAGAAGGATG AACCTTGCTT GATCCACAAT CTCAGGTTTC CTGATGCATG GCTAATGACA
TCCAAAACAG AGGTAATGTT ATTAAATCCA TATAGAGTAG AAGAAGCCCT GCTATTTAAA
AGACTTCTTG AGAATCATAA ACTTCCTGCA GAGCCACTGG AAAAGCCAAT TATGTTAACA
GAGAGTCTTT TTAATGGATC TCATTATTTA GACGTTTTAT ATAAAATGAC AGCAGATGAC
CAAAGATACA GTGGATCAAC TTACCTGTCT GATCCTCGTC TTACAGCGAA TGGTTTCAAG
ATAAAATTGA TACCAGGAGT TTCAATTACT GAAAATTACT TGGAAATAGA AGGAATGGCT
AATTGTCTCC CATTCTATGG AGTAGCAGAT TTAAAAGAAA TTCTTAATGC TATATTAAAC
AGAAATGCAA AGGAAGTTTA TGAATGTAGA CCTCGCAAAG TGATAAGTTA TTTAGAGGGA
GAAGCAGTGC GTCTATCCAG ACAATTACCC ATGTACTTAT CAAAAGAGGA CATCCAAGAC
ATTATCTACA GAATGAAGCA CCAGTTTGGA AATGAAATTA AAGAGTGTGT TCATGGTCGC
CCATTTTTTC ATCATTTAAC CTATCTTCCA GAAACTACAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001121615.1
CDS530..3211
Misc Feature(1)366..366(+)
Misc Feature(2)401..401(+)
Misc Feature(3)412..412(+)
Misc Feature(4)476..476(+)
Misc Feature(5)500..502(+)
Misc Feature(6)530..1366(+)
Misc Feature(7)596..>832(+)
Misc Feature(8)608..820(+)
Misc Feature(9)620..622(+)
Misc Feature(10)701..817(+)
Misc Feature(11)1109..1426(+)
Misc Feature(12)1352..1354(+)
Misc Feature(13)2126..2320(+)
Misc Feature(14)2129..2296(+)
Exon (1)1..509
Gene:PMS1
Gene Synonym:
Exon (2)510..661
Gene:PMS1
Gene Synonym:
Exon (3)662..844
Gene:PMS1
Gene Synonym:
Exon (4)845..947
Gene:PMS1
Gene Synonym:
Exon (5)948..1111
Gene:PMS1
Gene Synonym:
Exon (6)1112..1234
Gene:PMS1
Gene Synonym:
Exon (7)1235..1378
Gene:PMS1
Gene Synonym:
Exon (8)1379..2268
Gene:PMS1
Gene Synonym:
Exon (9)2269..2754
Gene:PMS1
Gene Synonym:
Exon (10)2755..2885
Gene:PMS1
Gene Synonym:
Exon (11)2886..3046
Gene:PMS1
Gene Synonym:
Exon (12)3047..3404
Gene:PMS1
Gene Synonym:
Translation
Position Chain Variation Link
20 20 a, g dbSNP:189547607
22 22 a, g dbSNP:536962444
23 23 c, t dbSNP:554655433
34 34 c, g dbSNP:750021361
41 41 a, g dbSNP:576428024
49 49 a, g dbSNP:5742927
53 53 c, g dbSNP:565412237
60 60 c, t dbSNP:757816314
70 70 c, t dbSNP:577428807
74 74 c, g dbSNP:11550049
89 89 g, t dbSNP:541196484
96 96 c, t dbSNP:559590295
137 137 a, c, g dbSNP:369675358
139 139 a, c dbSNP:529904737
175 175 a, g dbSNP:548513402
187 187 a, g dbSNP:5742928
194 194 c, t dbSNP:372712876
200 200 g, t dbSNP:758067747
207 207 c, t dbSNP:777624544
228 228 c, t dbSNP:5742929
232 232 g, t dbSNP:746616111
246 246 a, c dbSNP:551774070
250 250 a, c dbSNP:5742930
255 255 c, t dbSNP:5742931
256 256 a, t dbSNP:534415170
264 264 a, g dbSNP:547545719
271 271 a, c dbSNP:566304104
290 290 a, c dbSNP:536540364
296 296 c, t dbSNP:756536859
298 298 g, t dbSNP:745440258
350 350 c, g dbSNP:555270776
366 366 a, g dbSNP:777937194
371 371 c, t dbSNP:576342227
374 374 a, g dbSNP:147002700
380 380 c, t dbSNP:749530064
386 386 a, c, g dbSNP:375594683
409 409 -, gggtgc dbSNP:766501073
410 410 a, g dbSNP:757537327
422 422 c, g dbSNP:779071853
424 424 a, g dbSNP:556452424
427 427 c, t dbSNP:745993205
430 430 g, t dbSNP:5742932
431 431 g, t dbSNP:577363454
442 442 a, g dbSNP:541545004
446 446 c, g, t dbSNP:374103918
454 454 a, g dbSNP:559588204
483 483 a, g dbSNP:574605931
504 504 a, c dbSNP:771993432
506 506 c, g dbSNP:5742933
514 514 c, t dbSNP:757794123
515 515 c, t dbSNP:781605412
525 525 c, t dbSNP:570050132
526 526 a, g dbSNP:754586160
538 538 a, g dbSNP:373031044
540 540 c, t dbSNP:201944922
544 544 c, t dbSNP:778660303
546 546 c, t dbSNP:747835603
547 547 a, g dbSNP:771930754
551 551 a, g dbSNP:777641087
558 558 a, g dbSNP:370084230
561 561 c, t dbSNP:770894099
562 562 c, t dbSNP:762260830
563 563 a, c, t dbSNP:374261058
569 569 a, g dbSNP:775649361
570 570 a, g dbSNP:763166242
574 574 a, t dbSNP:377616727
576 576 a, g dbSNP:570876790
578 578 a, g dbSNP:151231718
585 585 c, g dbSNP:534847551
588 588 c, t dbSNP:768047966
589 589 g, t dbSNP:750916185
592 592 g, t dbSNP:754498304
599 599 a, g dbSNP:553130827
608 608 c, g dbSNP:5742973
635 635 a, g dbSNP:781053212
642 642 -, caagcg dbSNP:761879899
643 643 a, t dbSNP:758112220
644 644 a, g dbSNP:113193813
646 646 c, t dbSNP:777358818
647 647 a, g dbSNP:746784366
650 650 c, g dbSNP:757048301
651 651 a, c, g dbSNP:545600556
655 655 g, t dbSNP:769797470
669 669 a, g dbSNP:756031414
670 670 c, t dbSNP:5742980
681 681 a, c dbSNP:370668897
692 692 c, t dbSNP:375147123
696 696 a, g dbSNP:377024581
700 700 -, g dbSNP:765360578
700 700 c, t dbSNP:756254396
701 701 a, g dbSNP:772427166
702 702 a, g dbSNP:773700771
703 703 gg, ta dbSNP:587778608
703 703 g, t dbSNP:143323454
704 704 a, g dbSNP:143265397
728 728 c, t dbSNP:777322683
737 737 g, t dbSNP:753676547
740 740 a, g dbSNP:763541657
751 751 c, t dbSNP:751153318
753 753 c, t dbSNP:61756360
754 754 c, g dbSNP:201065617
759 759 -, aaat dbSNP:773464464
766 766 c, t dbSNP:750214766
771 771 a, g dbSNP:755941492
772 772 c, t dbSNP:150543935
786 786 a, t dbSNP:779918450
796 796 g, t dbSNP:753750267
797 797 -, a dbSNP:753745201
799 799 a, c, t dbSNP:149723996
800 800 a, g dbSNP:370300640
806 806 c, t dbSNP:772181508
807 807 a, c, g dbSNP:778185859
816 816 a, c, g, t dbSNP:139414606
816 816 -, c dbSNP:763126626
823 823 a, g dbSNP:541076815
827 827 a, g dbSNP:768152350
831 831 a, g dbSNP:773719324
834 834 a, g dbSNP:761453284
839 839 a, c, g dbSNP:200395679
845 845 c, g dbSNP:766079191
856 856 a, g dbSNP:146515816
858 858 c, g dbSNP:372752293
863 863 a, g dbSNP:765068532
864 864 c, t dbSNP:576285843
865 865 a, g dbSNP:543376612
866 866 g, t dbSNP:764270787
874 874 c, t dbSNP:2066457
883 883 c, t dbSNP:757537798
885 885 c, t dbSNP:781542667
899 899 c, g dbSNP:746186468
900 900 a, g dbSNP:756549435
903 903 a, g dbSNP:780386003
911 911 c, t dbSNP:576726933
914 914 a, g dbSNP:771514571
922 922 c, t dbSNP:772697027
929 929 a, c, t dbSNP:746592348
930 930 c, t dbSNP:776398978
932 932 a, t dbSNP:759206167
950 950 a, g dbSNP:773337973
958 958 a, g dbSNP:150245286
961 961 c, t dbSNP:370516860
963 963 c, g dbSNP:766604209
969 969 a, g dbSNP:113137368
981 981 a, g dbSNP:754084013
988 988 c, t dbSNP:759858356
1003 1003 a, t dbSNP:369474547
1005 1005 a, t dbSNP:765594171
1008 1008 c, t dbSNP:550220809
1014 1014 -, a dbSNP:779955300
1015 1015 -, a dbSNP:587778609
1018 1018 -, aaaatgt dbSNP:746998919
1025 1025 a, g dbSNP:758921945
1029 1029 a, g dbSNP:200244068
1052 1052 c, t dbSNP:749915619
1054 1054 c, t dbSNP:532912232
1059 1059 c, t dbSNP:755627056
1063 1063 a, c, t dbSNP:779802611
1070 1070 a, g dbSNP:768513050
1080 1080 a, c dbSNP:778838293
1084 1084 c, t dbSNP:73979090
1089 1089 a, g dbSNP:772016473
1098 1098 c, t dbSNP:773075006
1100 1100 g, t dbSNP:760761733
1103 1103 c, t dbSNP:771034057
1104 1104 a, g dbSNP:587778610
1107 1107 a, g dbSNP:776771191
1135 1135 a, g dbSNP:779243339
1138 1138 a, g dbSNP:56144843
1143 1143 a, t dbSNP:772593735
1148 1148 g, t dbSNP:75465207
1152 1152 a, g dbSNP:773786180
1175 1175 c, t dbSNP:769264049
1179 1179 a, g dbSNP:771521891
1181 1181 a, g dbSNP:774862999
1192 1192 c, t dbSNP:762568785
1198 1198 a, g dbSNP:763634931
1201 1201 c, t dbSNP:756974504
1202 1202 a, t dbSNP:751238299
1205 1205 c, t dbSNP:761558970
1224 1224 -, a dbSNP:774706986
1226 1226 a, g dbSNP:375164425
1227 1227 c, t dbSNP:767306276
1230 1230 c, t dbSNP:750303019
1231 1231 a, c dbSNP:755991524
1233 1233 a, c dbSNP:780079764
1238 1238 a, c dbSNP:777247528
1239 1239 c, t dbSNP:748700549
1241 1241 c, t dbSNP:768246348
1242 1242 a, g dbSNP:773928881
1248 1248 a, g dbSNP:761470579
1252 1252 c, g dbSNP:767216229
1274 1274 c, t dbSNP:772959693
1275 1275 c, t dbSNP:760566355
1277 1277 a, g dbSNP:766177870
1280 1280 c, t dbSNP:753843878
1281 1281 a, g dbSNP:183717609
1301 1301 c, g dbSNP:146040262
1307 1307 a, g dbSNP:752879186
1309 1309 c, t dbSNP:149988991
1311 1311 a, c dbSNP:574137844
1319 1319 a, g dbSNP:747316625
1320 1320 c, t dbSNP:757665441
1348 1348 a, g dbSNP:781513402
1352 1352 a, g dbSNP:148745528
1367 1367 a, t dbSNP:767995024
1370 1370 c, t dbSNP:773838917
1374 1374 a, g dbSNP:147901996
1375 1375 c, t dbSNP:202008207
1376 1376 a, g dbSNP:772872765
1379 1379 g, t dbSNP:777221902
1380 1380 a, g dbSNP:746684224
1397 1397 c, g, t dbSNP:770544182
1400 1400 c, g dbSNP:759285880
1411 1411 -, gac dbSNP:750135409
1413 1413 c, t dbSNP:147084726
1414 1414 a, g dbSNP:775595671
1415 1415 a, g dbSNP:763089248
1419 1419 a, g dbSNP:764276785
1423 1423 c, t dbSNP:751675535
1429 1429 a, g dbSNP:569336571
1430 1430 c, t dbSNP:762083170
1438 1438 c, t dbSNP:767698592
1439 1439 a, g dbSNP:750770322
1449 1449 a, g dbSNP:540051947
1450 1450 c, t dbSNP:780499163
1456 1456 a, taat dbSNP:386653706
1465 1465 a, g dbSNP:754345445
1466 1466 a, g dbSNP:757843914
1469 1469 a, g dbSNP:777321010
1472 1472 a, t dbSNP:746564566
1474 1474 c, t dbSNP:770583200
1475 1475 a, g dbSNP:141084536
1486 1486 c, t dbSNP:745613341
1487 1487 a, g dbSNP:369839744
1503 1503 c, t dbSNP:755937219
1530 1530 c, t dbSNP:199659366
1538 1538 -, c dbSNP:34800695
1541 1541 -, g dbSNP:758168664
1542 1542 c, g dbSNP:775503944
1555 1555 a, g dbSNP:763001065
1566 1566 c, g dbSNP:768772690
1570 1570 a, g dbSNP:779635858
1574 1574 a, c dbSNP:774486487
1579 1579 a, g dbSNP:761838436
1582 1582 c, g dbSNP:767757337
1584 1584 a, g dbSNP:750642262
1589 1589 g, t dbSNP:760960503
1590 1590 a, t dbSNP:766742199
1591 1591 c, t dbSNP:754255687
1593 1593 c, t dbSNP:1145231
1596 1596 a, g dbSNP:145375126
1603 1603 g, t dbSNP:567192785
1610 1610 -, g dbSNP:779867285
1611 1611 -, a dbSNP:746911496
1613 1613 a, t dbSNP:756743623
1621 1621 -, tga dbSNP:768607381
1634 1634 a, c dbSNP:768147034
1637 1637 -, cac dbSNP:777855415
1643 1643 a, g dbSNP:780862528
1653 1653 a, g dbSNP:745523368
1666 1666 c, t dbSNP:755918305
1674 1674 g, t dbSNP:142577664
1691 1691 a, g dbSNP:373271688
1693 1693 c, t dbSNP:749164046
1694 1694 a, g dbSNP:768607896
1704 1704 a, g dbSNP:774205801
1710 1710 a, c, g dbSNP:148690800
1712 1712 a, g dbSNP:534500725
1717 1717 a, g dbSNP:760872306
1723 1723 a, c, g dbSNP:55726197
1724 1724 c, g dbSNP:776947297
1733 1733 a, g dbSNP:759938479
1738 1738 g, t dbSNP:765723624
1740 1740 a, g dbSNP:200407029
1741 1741 c, t dbSNP:189863121
1741 1741 -, t dbSNP:763044411
1742 1742 g, t dbSNP:369312075
1744 1744 a, c, g dbSNP:534243480
1745 1745 c, t dbSNP:373224158
1760 1760 c, t dbSNP:779894503
1761 1761 a, g dbSNP:56305733
1764 1764 c, t dbSNP:181493700
1765 1765 a, g dbSNP:754752991
1769 1769 a, t dbSNP:778843582
1775 1775 a, g dbSNP:748046504
1788 1788 -, a dbSNP:749329798
1792 1792 g, t dbSNP:768758116
1792 1792 -, t dbSNP:771104806
1795 1795 c, t dbSNP:747621119
1798 1798 a, t dbSNP:773272437
1806 1806 c, t dbSNP:747129479
1819 1819 a, t dbSNP:144599126
1830 1830 a, t dbSNP:776857506
1831 1831 c, g dbSNP:759908270
1834 1834 c, t dbSNP:765529423
1836 1836 c, t dbSNP:371392948
1839 1839 a, g dbSNP:571235425
1841 1841 g, t dbSNP:764765315
1847 1847 a, g dbSNP:749923368
1848 1848 c, g dbSNP:587778612
1864 1864 a, g dbSNP:766081471
1884 1884 c, t dbSNP:753545002
1885 1885 a, g dbSNP:754744032
1889 1889 a, c dbSNP:778557193
1893 1893 c, t dbSNP:752602525
1895 1895 a, g dbSNP:758235016
1898 1898 a, g dbSNP:777734081
1899 1899 a, g dbSNP:375640863
1900 1900 c, t dbSNP:747037734
1908 1908 a, g dbSNP:775222893
1913 1913 a, g dbSNP:1145232
1916 1916 a, t dbSNP:781328782
1919 1919 a, g dbSNP:746096258
1920 1920 a, c, t dbSNP:770115265
1952 1952 c, g dbSNP:368282144
1954 1954 c, t dbSNP:763416734
1983 1983 c, g, t dbSNP:560096410
1988 1988 c, t dbSNP:760223545
1998 1998 a, g dbSNP:56064816
2001 2001 a, g dbSNP:753446372
2011 2011 g, t dbSNP:759105195
2018 2018 c, t dbSNP:201236867
2021 2021 a, g dbSNP:151325573
2033 2033 c, t dbSNP:759894015
2035 2035 g, t dbSNP:113372387
2038 2038 c, t dbSNP:777644154
2042 2042 g, t dbSNP:751506189
2046 2046 a, c dbSNP:757273212
2049 2049 a, g dbSNP:531239757
2053 2053 -, a dbSNP:774420632
2055 2055 a, g dbSNP:61736576
2056 2056 a, g dbSNP:769876795
2071 2071 a, c dbSNP:780372372
2073 2073 a, g dbSNP:749568233
2090 2090 -, g dbSNP:759884049
2096 2096 g, t dbSNP:189785572
2097 2097 a, c, t dbSNP:774939385
2102 2102 a, g dbSNP:531589926
2104 2104 c, t dbSNP:775824945
2108 2108 c, g dbSNP:140854388
2117 2117 c, t dbSNP:201194903
2118 2118 a, g dbSNP:138610933
2120 2120 a, g dbSNP:775236748
2126 2126 a, g dbSNP:762666544
2145 2145 a, g dbSNP:768653497
2154 2154 -, ttg dbSNP:772532489
2156 2156 a, g dbSNP:74512161
2168 2168 a, c, t dbSNP:566975683
2169 2169 a, g dbSNP:750449314
2181 2181 g, t dbSNP:756240681
2182 2182 c, t dbSNP:780100887
2184 2184 c, t dbSNP:749530914
2194 2194 g, t dbSNP:755308444
2203 2203 g, t dbSNP:139552807
2204 2204 a, t dbSNP:748563735
2206 2206 a, c dbSNP:772681534
2210 2210 a, g dbSNP:773787379
2211 2211 a, g dbSNP:745326955
2212 2212 c, t dbSNP:769347993
2213 2213 a, g dbSNP:147450758
2216 2216 a, g dbSNP:762582922
2242 2242 c, g dbSNP:751603605
2245 2245 a, g dbSNP:550510753
2246 2246 c, t dbSNP:763806939
2257 2257 a, c, g dbSNP:774104441
2260 2260 a, g dbSNP:767309798
2265 2265 g, t dbSNP:145406444
2281 2281 c, g dbSNP:567568410
2282 2282 a, g dbSNP:759618103
2291 2291 c, g dbSNP:765418665
2296 2296 a, g, t dbSNP:752879348
2300 2300 c, t dbSNP:139932286
2301 2301 a, g dbSNP:751934617
2307 2307 a, g dbSNP:2066456
2314 2314 a, g dbSNP:371000056
2324 2324 a, g dbSNP:750934823
2328 2328 g, t dbSNP:754429223
2347 2347 a, g dbSNP:778382887
2365 2365 -, a dbSNP:764521118
2387 2387 a, g dbSNP:747650016
2389 2389 a, g dbSNP:771732109
2401 2401 c, t dbSNP:777313675
2421 2421 c, g dbSNP:746778101
2430 2430 c, t dbSNP:770849733
2432 2432 a, c dbSNP:374303819
2450 2450 a, g dbSNP:745785113
2468 2468 a, g dbSNP:775854930
2469 2469 c, t dbSNP:769922512
2470 2470 g, t dbSNP:587778614
2472 2472 a, t dbSNP:377266054
2476 2476 -, aag dbSNP:777263508
2489 2489 a, g dbSNP:113616678
2490 2490 a, g, t dbSNP:369814333
2509 2509 a, c dbSNP:774468225
2511 2511 c, t dbSNP:370578519
2518 2518 a, t dbSNP:374605857
2519 2519 a, g dbSNP:750847463
2522 2522 a, g dbSNP:756580931
2527 2527 -, attt dbSNP:761216715
2531 2531 -, aaaat dbSNP:764853982
2535 2535 c, t dbSNP:766919900
2546 2546 -, aaaca dbSNP:750048736
2555 2555 a, g dbSNP:752201789
2558 2558 a, g dbSNP:757877460
2566 2566 -, agaag dbSNP:758080998
2572 2572 c, g dbSNP:2066455
2574 2574 a, g dbSNP:777413446
2577 2577 a, g dbSNP:746652083
2579 2579 a, g dbSNP:61736573
2581 2581 a, g dbSNP:781127435
2585 2585 c, t dbSNP:745701071
2598 2598 a, g dbSNP:201205478
2619 2619 a, g dbSNP:368630253
2620 2620 a, g dbSNP:749351122
2631 2631 c, t dbSNP:587778613
2637 2637 c, t dbSNP:201778750
2638 2638 -, a dbSNP:766117735
2659 2659 a, t dbSNP:768622783
2661 2661 a, g dbSNP:774576220
2665 2665 a, g dbSNP:761928375
2669 2669 a, g dbSNP:767796763
2676 2676 c, g dbSNP:773542405
2682 2682 c, t dbSNP:761048343
2689 2689 a, t dbSNP:766830290
2693 2693 c, t dbSNP:754305507
2695 2695 c, t dbSNP:150341545
2696 2696 a, c dbSNP:538489643
2701 2701 g, t dbSNP:751145104
2702 2702 a, c dbSNP:375553851
2704 2704 c, t dbSNP:781043612
2711 2711 c, g dbSNP:188947672
2712 2712 c, g, t dbSNP:756008351
2722 2722 a, g dbSNP:749197166
2723 2723 a, c dbSNP:143686298
2729 2729 c, g dbSNP:778857327
2738 2738 a, g dbSNP:748274684
2742 2742 c, t dbSNP:772231922
2750 2750 a, g dbSNP:193252599
2753 2753 a, g dbSNP:201984263
2763 2763 a, g dbSNP:55680602
2765 2765 c, g dbSNP:777821897
2770 2770 c, t dbSNP:201324347
2775 2775 a, g dbSNP:553828991
2781 2781 a, t dbSNP:757396542
2782 2782 c, t dbSNP:762377532
2783 2783 a, g dbSNP:781501975
2789 2789 c, g, t dbSNP:1145234
2790 2790 a, g dbSNP:770203209
2792 2792 a, t dbSNP:776086491
2797 2797 g, t dbSNP:749800455
2800 2800 a, g dbSNP:769354925
2812 2812 a, g dbSNP:150865251
2819 2819 a, c dbSNP:760284046
2829 2829 c, g dbSNP:55859858
2832 2832 a, t dbSNP:200919195
2834 2834 c, g dbSNP:759191350
2846 2846 c, t dbSNP:371745827
2847 2847 a, g, t dbSNP:375020232
2852 2852 a, g dbSNP:200172149
2853 2853 c, g dbSNP:369226504
2854 2854 a, g dbSNP:777704189
2856 2856 c, t dbSNP:139826569
2862 2862 a, g, t dbSNP:781206054
2872 2872 a, g dbSNP:756353601
2882 2882 a, c dbSNP:587778611
2905 2905 c, t dbSNP:576339546
2908 2908 c, g dbSNP:756377066
2912 2912 g, t dbSNP:780475445
2930 2930 a, g dbSNP:369909997
2934 2934 a, g dbSNP:755396415
2946 2946 a, g dbSNP:779501477
2951 2951 -, g dbSNP:772445011
2952 2952 c, t dbSNP:199892342
2953 2953 a, g dbSNP:772517576
2967 2967 a, c dbSNP:145521752
2970 2970 c, t dbSNP:745418589
2976 2976 a, c, g, t dbSNP:56309301
2982 2982 c, t dbSNP:762670803
2988 2988 a, g dbSNP:768453779
2999 2999 a, g dbSNP:774072907
3003 3003 a, g dbSNP:761809273
3007 3007 a, t dbSNP:767398078
3015 3015 a, g dbSNP:564962629
3023 3023 c, t dbSNP:143554211
3024 3024 a, g, t dbSNP:760863069
3024 3024 -, g dbSNP:775939224
3056 3056 a, g dbSNP:374222815
3059 3059 -, a dbSNP:769123166
3059 3059 c, t dbSNP:142159998
3060 3060 -, acgc dbSNP:776982819
3060 3060 a, g dbSNP:377603311
3061 3061 a, t dbSNP:748840882
3068 3068 a, t dbSNP:754639850
3073 3073 a, g dbSNP:61748257
3074 3074 c, t dbSNP:370611400
3077 3077 c, g dbSNP:374879205
3080 3080 a, t dbSNP:537745271
3083 3083 -, tact dbSNP:762425602
3085 3085 -, tta dbSNP:764615055
3096 3096 a, g dbSNP:746934898
3101 3101 a, t dbSNP:771027683
3105 3105 a, g dbSNP:776829529
3110 3110 a, g dbSNP:759710002
3117 3117 a, g dbSNP:765457307
3122 3122 a, c dbSNP:775577121
3128 3128 c, t dbSNP:763320793
3131 3131 c, g dbSNP:775695414
3147 3147 c, t dbSNP:764353574
3164 3164 a, g dbSNP:751989008
3166 3166 c, t dbSNP:757731143
3167 3167 c, t dbSNP:145103030
3168 3168 a, g, t dbSNP:147566508
3181 3181 a, t dbSNP:778563772
3188 3188 a, g dbSNP:138906915
3191 3191 c, t dbSNP:758133616
3192 3192 a, g dbSNP:111254723
3213 3213 a, t dbSNP:746846733
3221 3221 a, t dbSNP:5743199
3224 3224 -, aag dbSNP:772733884
3226 3226 g, t dbSNP:768386630
3247 3247 g, t dbSNP:745892695
3264 3264 c, t dbSNP:774172390
3266 3266 a, g dbSNP:764216417
3271 3271 a, g dbSNP:553749816
3288 3288 -, t dbSNP:753967087
3298 3298 a, g dbSNP:761210807
3323 3323 c, t dbSNP:572013326
3349 3349 c, t dbSNP:112239654
3378 3378 c, t dbSNP:542744208
3393 3393 a, g dbSNP:562248054
3400 3400 a, c dbSNP:767117479

Target ORF information:

RefSeq Version NM_001128143
Organism Homo sapiens (human)
Definition Homo sapiens PMS1 homolog 1, mismatch repair system component (PMS1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001128143

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
ATGAAACAAT TGCCTGCGGC AACAGTTCGA CTCCTTTCAA GTTCTCAGAT CATCACTTCG 
GTGGTCAGTG TTGTAAAAGA GCTTATTGAA AACTCCTTGG ATGCTGGTGC CACAAGCGTA
GATGTTAAAC TGGAGAACTA TGGATTTGAT AAAATTGAGG TGCGAGATAA CGGGGAGGGT
ATCAAGGCTG TTGATGCACC TGTAATGGCA ATGAAGTACT ACACCTCAAA AATAAATAGT
CATGAAGATC TTGAAAATTT GACAACTTAC GGTTTTCGTG GAGAAGCCTT GGGGTCAATT
TGTTGTATAG CTGAGGTTTT AATTACAACA AGAACGGCTG CTGATAATTT TAGCACCCAG
TATGTTTTAG ATGGCAGTGG CCACATACTT TCTCAGAAAC CTTCACATCT TGGTCAAGGT
ACAACTGTAA CTGCTTTAAG ATTATTTAAG AATCTACCTG TAAGAAAGCA GTTTTACTCA
ACTGCAAAAA AATGTAAAGA TGAAATAAAA AAGATCCAAG ATCTCCTCAT GAGCTTTGGT
ATCCTTAAAC CTGACTTAAG GATTGTCTTT GTACATAACA AGATTTATCT CAGTGGATTT
CTTCCAAAGT GTGATGCAGA CCACTCTTTC ACTAGTCTTT CAACACCAGA AAGAAGTTTC
ATCTTCATAA ACAGTCGACC AGTACATCAA AAAGATATCT TAAAGTTAAT CCGACATCAT
TACAATCTGA AATGCCTAAA GGAATCTACT CGTTTGTATC CTGTTTTCTT TCTGAAAATC
GATGTTCCTA CAGCTGATGT TGATGTAAAT TTAACACCAG ATAAAAGCCA AGTATTATTA
CAAAATAAGG AATCTGTTTT AATTGCTCTT GAAAATCTGA TGACGACTTG TTATGGACCA
TTACCTAGTA CAAATTCTTA TGAAAATAAT AAAACAGATG TTTCCGCAGC TGACATCGTT
CTTAGTAAAA CAGCAGAAAC AGATGTGCTT TTTAATAAAG TGGAATCATC TGGAAAGAAT
TATTCAAATG TTGATACTTC AGTCATTCCA TTCCAAAATG ATATGCATAA TGATGAATCT
GGAAAAAACA CTGATGATTG TTTAAATCAC CAGATAAGTA TTGGTGACTT TGGTTATGGT
CATTGTAGTA GTGAAATTTC TAACATTGAT AAAAACACTA AGAATGCATT TCAGGACATT
TCAATGAGTA ATGTATCATG GGAGAACTCT CAGACGGAAT ATAGTAAAAC TTGTTTTATA
AGTTCCGTTA AGCACACCCA GTCAGAAAAT GGCAATAAAG ACCATATAGA TGAGAGTGGG
GAAAATGAGG AAGAAGCAGG TCTTGAAAAC TCTTCGGAAA TTTCTGCAGA TGAGTGGAGC
AGGGGAAATA TACTTAAAAA TTCAGTGGGA GAGAATATTG AACCTGTGAA AATTTTAGTG
CCTGAAAAAA GTTTACCATG TAAAGTAAGT AATAATAATT ATCCAATCCC TGAACAAATG
AATCTTAATG AAGATTCATG TAACAAAAAA TCAAATGTAA TAGATAATAA ATCTGGAAAA
GTTACAGCTT ATGATTTACT TAGCAATCGA GTAATCAAGA AACCCATGTC AGCAAGTGCT
CTTTTTGTTC AAGATCATCG TCCTCAGTTT CTCATAGAAA ATCCTAAGAC TAGTTTAGAG
GATGCAACAC TACAAATTGA AGAACTGTGG AAGACATTGA GTGAAGAGGA AAAACTGAAA
TATGAAGAGA AGGCTACTAA AGACTTGGAA CGATACAATA GTCAAATGAA GAGAGCCATT
GAACAGGAGT CACAAATGTC ACTAAAAGAT GGCAGAAAAA AGATAAAACC CACCAGCGCA
TGGAATTTGG CCCAGAAGCA CAAGTTAAAA ACCTCATTAT CTAATCAACC AAAACTTGAT
GAACTCCTTC AGTCCCAAAT TGAAAAAAGA AGGAGTCAAA ATATTAAAAT GGTACAGATC
CCCTTTTCTA TGAAAAACTT AAAAATAAAT TTTAAGAAAC AAAACAAAGT TGACTTAGAA
GAGAAGGATG AACCTTGCTT GATCCACAAT CTCAGGTTTC CTGATGCATG GCTAATGACA
TCCAAAACAG AGGTAATGTT ATTAAATCCA TATAGAGTAG AAGAAGCCCT GCTATTTAAA
AGACTTCTTG AGAATCATAA ACTTCCTGCA GAGCCACTGG AAAAGCCAAT TATGTTAACA
GAGAGTCTTT TTAATGGATC TCATTATTTA GACGTTTTAT ATAAAATGAC AGCAGATGAC
CAAAGATACA GTGGATCAAC TTACCTGTCT GATCCTCGTC TTACAGCGAA TGGTTTCAAG
ATAAAATTGA TACCAGGAGT TTCAATTACT GAAAATTACT TGGAAATAGA AGGAATGGCT
AATTGTCTCC CATTCTATGG AGTAGCAGAT TTAAAAGAAA TTCTTAATGC TATATTAAAC
AGAAATGCAA AGGAAGTTTA TGAATGTAGA CCTCGCAAAG TGATAAGTTA TTTAGAGGGA
GAAGCAGTGC GTCTATCCAG ACAATTACCC ATGTACTTAT CAAAAGAGGA CATCCAAGAC
ATTATCTACA GAATGAAGCA CCAGTTTGGA AATGAAATTA AAGAGTGTGT TCATGGTCGC
CCATTTTTTC ATCATTTAAC CTATCTTCCA GAAACTACAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16750
Accession Version NM_001289408.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2271bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 13-JUL-2015
Organism Homo sapiens (human)
Product PMS1 protein homolog 1 isoform d
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC347859.1, AK295602.1, BC096332.1 and BG195153.1. Summary: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (4) lacks an exon in the 5' coding region, and uses a downstream translation start, compared to variant 1. The encoded protein (isoform d) has a shorter N-terminus, compared to isoform a. Variants 4 and 5 both encode isoform d. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK295602.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGAGCTTTG GTATCCTTAA ACCTGACTTA AGGATTGTCT TTGTACATAA CAAGGCAGTT 
ATTTGGCAGA AAAGCAGAGT ATCAGATCAC AAGATGGCTC TCATGTCAGT TCTGGGGACT
GCTGTTATGA ACAATATGGA ATCCTTTCAG TACCACTCTG AAGAATCTCA GATTTATCTC
AGTGGATTTC TTCCAAAGTG TGATGCAGAC CACTCTTTCA CTAGTCTTTC AACACCAGAA
AGAAGTTTCA TCTTCATAAA CAGTCGACCA GTACATCAAA AAGATATCTT AAAGTTAATC
CGACATCATT ACAATCTGAA ATGCCTAAAG GAATCTACTC GTTTGTATCC TGTTTTCTTT
CTGAAAATCG ATGTTCCTAC AGCTGATGTT GATGTAAATT TAACACCAGA TAAAAGCCAA
GTATTATTAC AAAATAAGGA ATCTGTTTTA ATTGCTCTTG AAAATCTGAT GACGACTTGT
TATGGACCAT TACCTAGTAC AAATTCTTAT GAAAATAATA AAACAGATGT TTCCGCAGCT
GACATCGTTC TTAGTAAAAC AGCAGAAACA GATGTGCTTT TTAATAAAGT GGAATCATCT
GGAAAGAATT ATTCAAATGT TGATACTTCA GTCATTCCAT TCCAAAATGA TATGCATAAT
GATGAATCTG GAAAAAACAC TGATGATTGT TTAAATCACC AGATAAGTAT TGGTGACTTT
GGTTATGGTC ATTGTAGTAG TGAAATTTCT AACATTGATA AAAACACTAA GAATGCATTT
CAGGACATTT CAATGAGTAA TGTATCATGG GAGAACTCTC AGACGGAATA TAGTAAAACT
TGTTTTATAA GTTCCGTTAA GCACACCCAG TCAGAAAATG GCAATAAAGA CCATATAGAT
GAGAGTGGGG AAAATGAGGA AGAAGCAGGT CTTGAAAACT CTTCGGAAAT TTCTGCAGAT
GAGTGGAGCA GGGGAAATAT ACTTAAAAAT TCAGTGGGAG AGAATATTGA ACCTGTGAAA
ATTTTAGTGC CTGAAAAAAG TTTACCATGT AAAGTAAGTA ATAATAATTA TCCAATCCCT
GAACAAATGA ATCTTAATGA AGATTCATGT AACAAAAAAT CAAATGTAAT AGATAATAAA
TCTGGAAAAG TTACAGCTTA TGATTTACTT AGCAATCGAG TAATCAAGAA ACCCATGTCA
GCAAGTGCTC TTTTTGTTCA AGATCATCGT CCTCAGTTTC TCATAGAAAA TCCTAAGACT
AGTTTAGAGG ATGCAACACT ACAAATTGAA GAACTGTGGA AGACATTGAG TGAAGAGGAA
AAACTGAAAT ATGAAGAGAA GGCTACTAAA GACTTGGAAC GATACAATAG TCAAATGAAG
AGAGCCATTG AACAGGAGTC ACAAATGTCA CTAAAAGATG GCAGAAAAAA GATAAAACCC
ACCAGCGCAT GGAATTTGGC CCAGAAGCAC AAGTTAAAAA CCTCATTATC TAATCAACCA
AAACTTGATG AACTCCTTCA GTCCCAAATT GAAAAAAGAA GGAGTCAAAA TATTAAAATG
GTACAGATCC CCTTTTCTAT GAAAAACTTA AAAATAAATT TTAAGAAACA AAACAAAGTT
GACTTAGAAG AGAAGGATGA ACCTTGCTTG ATCCACAATC TCAGGTTTCC TGATGCATGG
CTAATGACAT CCAAAACAGA GGTAATGTTA TTAAATCCAT ATAGAGTAGA AGAAGCCCTG
CTATTTAAAA GACTTCTTGA GAATCATAAA CTTCCTGCAG AGCCACTGGA AAAGCCAATT
ATGTTAACAG AGAGTCTTTT TAATGGATCT CATTATTTAG ACGTTTTATA TAAAATGACA
GCAGATGACC AAAGATACAG TGGATCAACT TACCTGTCTG ATCCTCGTCT TACAGCGAAT
GGTTTCAAGA TAAAATTGAT ACCAGGAGTT TCAATTACTG AAAATTACTT GGAAATAGAA
GGAATGGCTA ATTGTCTCCC ATTCTATGGA GTAGCAGATT TAAAAGAAAT TCTTAATGCT
ATATTAAACA GAAATGCAAA GGAAGTTTAT GAATGTAGAC CTCGCAAAGT GATAAGTTAT
TTAGAGGGAG AAGCAGTGCG TCTATCCAGA CAATTACCCA TGTACTTATC AAAAGAGGAC
ATCCAAGACA TTATCTACAG AATGAAGCAC CAGTTTGGAA ATGAAATTAA AGAGTGTGTT
CATGGTCGCC CATTTTTTCA TCATTTAACC TATCTTCCAG AAACTACATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001276337.1
CDS955..3225
Misc Feature(1)841..843(+)
Misc Feature(2)1039..1440(+)
Misc Feature(3)1366..1368(+)
Misc Feature(4)2140..2334(+)
Misc Feature(5)2143..2310(+)
Exon (1)1..509
Gene:PMS1
Gene Synonym:
Exon (2)510..661
Gene:PMS1
Gene Synonym:
Exon (3)662..844
Gene:PMS1
Gene Synonym:
Exon (4)845..1008
Gene:PMS1
Gene Synonym:
Exon (5)1009..1125
Gene:PMS1
Gene Synonym:
Exon (6)1126..1248
Gene:PMS1
Gene Synonym:
Exon (7)1249..1392
Gene:PMS1
Gene Synonym:
Exon (8)1393..2282
Gene:PMS1
Gene Synonym:
Exon (9)2283..2768
Gene:PMS1
Gene Synonym:
Exon (10)2769..2899
Gene:PMS1
Gene Synonym:
Exon (11)2900..3060
Gene:PMS1
Gene Synonym:
Exon (12)3061..3418
Gene:PMS1
Gene Synonym:
Translation
Position Chain Variation Link
20 20 a, g dbSNP:189547607
22 22 a, g dbSNP:536962444
23 23 c, t dbSNP:554655433
34 34 c, g dbSNP:750021361
41 41 a, g dbSNP:576428024
49 49 a, g dbSNP:5742927
53 53 c, g dbSNP:565412237
60 60 c, t dbSNP:757816314
70 70 c, t dbSNP:577428807
74 74 c, g dbSNP:11550049
89 89 g, t dbSNP:541196484
96 96 c, t dbSNP:559590295
137 137 a, c, g dbSNP:369675358
139 139 a, c dbSNP:529904737
175 175 a, g dbSNP:548513402
187 187 a, g dbSNP:5742928
194 194 c, t dbSNP:372712876
200 200 g, t dbSNP:758067747
207 207 c, t dbSNP:777624544
228 228 c, t dbSNP:5742929
232 232 g, t dbSNP:746616111
246 246 a, c dbSNP:551774070
250 250 a, c dbSNP:5742930
255 255 c, t dbSNP:5742931
256 256 a, t dbSNP:534415170
264 264 a, g dbSNP:547545719
271 271 a, c dbSNP:566304104
290 290 a, c dbSNP:536540364
296 296 c, t dbSNP:756536859
298 298 g, t dbSNP:745440258
350 350 c, g dbSNP:555270776
366 366 a, g dbSNP:777937194
371 371 c, t dbSNP:576342227
374 374 a, g dbSNP:147002700
380 380 c, t dbSNP:749530064
386 386 a, c, g dbSNP:375594683
409 409 -, gggtgc dbSNP:766501073
410 410 a, g dbSNP:757537327
422 422 c, g dbSNP:779071853
424 424 a, g dbSNP:556452424
427 427 c, t dbSNP:745993205
430 430 g, t dbSNP:5742932
431 431 g, t dbSNP:577363454
442 442 a, g dbSNP:541545004
446 446 c, g, t dbSNP:374103918
454 454 a, g dbSNP:559588204
483 483 a, g dbSNP:574605931
504 504 a, c dbSNP:771993432
506 506 c, g dbSNP:5742933
514 514 c, t dbSNP:757794123
515 515 c, t dbSNP:781605412
525 525 c, t dbSNP:570050132
526 526 a, g dbSNP:754586160
538 538 a, g dbSNP:373031044
540 540 c, t dbSNP:201944922
544 544 c, t dbSNP:778660303
546 546 c, t dbSNP:747835603
547 547 a, g dbSNP:771930754
551 551 a, g dbSNP:777641087
558 558 a, g dbSNP:370084230
561 561 c, t dbSNP:770894099
562 562 c, t dbSNP:762260830
563 563 a, c, t dbSNP:374261058
569 569 a, g dbSNP:775649361
570 570 a, g dbSNP:763166242
574 574 a, t dbSNP:377616727
576 576 a, g dbSNP:570876790
578 578 a, g dbSNP:151231718
585 585 c, g dbSNP:534847551
588 588 c, t dbSNP:768047966
589 589 g, t dbSNP:750916185
592 592 g, t dbSNP:754498304
599 599 a, g dbSNP:553130827
608 608 c, g dbSNP:5742973
635 635 a, g dbSNP:781053212
642 642 -, caagcg dbSNP:761879899
643 643 a, t dbSNP:758112220
644 644 a, g dbSNP:113193813
646 646 c, t dbSNP:777358818
647 647 a, g dbSNP:746784366
650 650 c, g dbSNP:757048301
651 651 a, c, g dbSNP:545600556
655 655 g, t dbSNP:769797470
669 669 a, g dbSNP:756031414
670 670 c, t dbSNP:5742980
681 681 a, c dbSNP:370668897
692 692 c, t dbSNP:375147123
696 696 a, g dbSNP:377024581
700 700 -, g dbSNP:765360578
700 700 c, t dbSNP:756254396
701 701 a, g dbSNP:772427166
702 702 a, g dbSNP:773700771
703 703 gg, ta dbSNP:587778608
703 703 g, t dbSNP:143323454
704 704 a, g dbSNP:143265397
728 728 c, t dbSNP:777322683
737 737 g, t dbSNP:753676547
740 740 a, g dbSNP:763541657
751 751 c, t dbSNP:751153318
753 753 c, t dbSNP:61756360
754 754 c, g dbSNP:201065617
759 759 -, aaat dbSNP:773464464
766 766 c, t dbSNP:750214766
771 771 a, g dbSNP:755941492
772 772 c, t dbSNP:150543935
786 786 a, t dbSNP:779918450
796 796 g, t dbSNP:753750267
797 797 -, a dbSNP:753745201
799 799 a, c, t dbSNP:149723996
800 800 a, g dbSNP:370300640
806 806 c, t dbSNP:772181508
807 807 a, c, g dbSNP:778185859
816 816 a, c, g, t dbSNP:139414606
816 816 -, c dbSNP:763126626
823 823 a, g dbSNP:541076815
827 827 a, g dbSNP:768152350
831 831 a, g dbSNP:773719324
834 834 a, g dbSNP:761453284
839 839 a, c, g dbSNP:200395679
847 847 a, g dbSNP:773337973
855 855 a, g dbSNP:150245286
858 858 c, t dbSNP:370516860
860 860 c, g dbSNP:766604209
866 866 a, g dbSNP:113137368
878 878 a, g dbSNP:754084013
885 885 c, t dbSNP:759858356
900 900 a, t dbSNP:369474547
902 902 a, t dbSNP:765594171
905 905 c, t dbSNP:550220809
911 911 -, a dbSNP:779955300
912 912 -, a dbSNP:587778609
915 915 -, aaaatgt dbSNP:746998919
922 922 a, g dbSNP:758921945
926 926 a, g dbSNP:200244068
949 949 c, t dbSNP:749915619
951 951 c, t dbSNP:532912232
956 956 c, t dbSNP:755627056
960 960 a, c, t dbSNP:779802611
967 967 a, g dbSNP:768513050
977 977 a, c dbSNP:778838293
981 981 c, t dbSNP:73979090
986 986 a, g dbSNP:772016473
995 995 c, t dbSNP:773075006
997 997 g, t dbSNP:760761733
1000 1000 c, t dbSNP:771034057
1001 1001 a, g dbSNP:587778610
1004 1004 a, g dbSNP:776771191
1016 1016 a, t dbSNP:185306467
1020 1020 g, t dbSNP:143010673
1022 1022 a, c dbSNP:774854343
1028 1028 g, t dbSNP:762396678
1029 1029 c, t dbSNP:141178436
1031 1031 a, g dbSNP:2066459
1033 1033 -, t dbSNP:773199906
1034 1034 c, t dbSNP:754586112
1039 1039 c, g dbSNP:764936813
1040 1040 a, t dbSNP:752326070
1042 1042 c, g, t dbSNP:758149651
1044 1044 -, c dbSNP:763190120
1052 1052 c, t dbSNP:746884261
1054 1054 c, g dbSNP:757185669
1058 1058 c, t dbSNP:781151298
1068 1068 a, g dbSNP:745928666
1082 1082 c, t dbSNP:769887269
1091 1091 c, t dbSNP:775742142
1104 1104 c, g dbSNP:749477891
1123 1123 c, t dbSNP:121434628
1149 1149 a, g dbSNP:779243339
1152 1152 a, g dbSNP:56144843
1157 1157 a, t dbSNP:772593735
1162 1162 g, t dbSNP:75465207
1166 1166 a, g dbSNP:773786180
1189 1189 c, t dbSNP:769264049
1193 1193 a, g dbSNP:771521891
1195 1195 a, g dbSNP:774862999
1206 1206 c, t dbSNP:762568785
1212 1212 a, g dbSNP:763634931
1215 1215 c, t dbSNP:756974504
1216 1216 a, t dbSNP:751238299
1219 1219 c, t dbSNP:761558970
1238 1238 -, a dbSNP:774706986
1240 1240 a, g dbSNP:375164425
1241 1241 c, t dbSNP:767306276
1244 1244 c, t dbSNP:750303019
1245 1245 a, c dbSNP:755991524
1247 1247 a, c dbSNP:780079764
1252 1252 a, c dbSNP:777247528
1253 1253 c, t dbSNP:748700549
1255 1255 c, t dbSNP:768246348
1256 1256 a, g dbSNP:773928881
1262 1262 a, g dbSNP:761470579
1266 1266 c, g dbSNP:767216229
1288 1288 c, t dbSNP:772959693
1289 1289 c, t dbSNP:760566355
1291 1291 a, g dbSNP:766177870
1294 1294 c, t dbSNP:753843878
1295 1295 a, g dbSNP:183717609
1315 1315 c, g dbSNP:146040262
1321 1321 a, g dbSNP:752879186
1323 1323 c, t dbSNP:149988991
1325 1325 a, c dbSNP:574137844
1333 1333 a, g dbSNP:747316625
1334 1334 c, t dbSNP:757665441
1362 1362 a, g dbSNP:781513402
1366 1366 a, g dbSNP:148745528
1381 1381 a, t dbSNP:767995024
1384 1384 c, t dbSNP:773838917
1388 1388 a, g dbSNP:147901996
1389 1389 c, t dbSNP:202008207
1390 1390 a, g dbSNP:772872765
1393 1393 g, t dbSNP:777221902
1394 1394 a, g dbSNP:746684224
1411 1411 c, g, t dbSNP:770544182
1414 1414 c, g dbSNP:759285880
1425 1425 -, gac dbSNP:750135409
1427 1427 c, t dbSNP:147084726
1428 1428 a, g dbSNP:775595671
1429 1429 a, g dbSNP:763089248
1433 1433 a, g dbSNP:764276785
1437 1437 c, t dbSNP:751675535
1443 1443 a, g dbSNP:569336571
1444 1444 c, t dbSNP:762083170
1452 1452 c, t dbSNP:767698592
1453 1453 a, g dbSNP:750770322
1463 1463 a, g dbSNP:540051947
1464 1464 c, t dbSNP:780499163
1470 1470 a, taat dbSNP:386653706
1479 1479 a, g dbSNP:754345445
1480 1480 a, g dbSNP:757843914
1483 1483 a, g dbSNP:777321010
1486 1486 a, t dbSNP:746564566
1488 1488 c, t dbSNP:770583200
1489 1489 a, g dbSNP:141084536
1500 1500 c, t dbSNP:745613341
1501 1501 a, g dbSNP:369839744
1517 1517 c, t dbSNP:755937219
1544 1544 c, t dbSNP:199659366
1552 1552 -, c dbSNP:34800695
1555 1555 -, g dbSNP:758168664
1556 1556 c, g dbSNP:775503944
1569 1569 a, g dbSNP:763001065
1580 1580 c, g dbSNP:768772690
1584 1584 a, g dbSNP:779635858
1588 1588 a, c dbSNP:774486487
1593 1593 a, g dbSNP:761838436
1596 1596 c, g dbSNP:767757337
1598 1598 a, g dbSNP:750642262
1603 1603 g, t dbSNP:760960503
1604 1604 a, t dbSNP:766742199
1605 1605 c, t dbSNP:754255687
1607 1607 c, t dbSNP:1145231
1610 1610 a, g dbSNP:145375126
1617 1617 g, t dbSNP:567192785
1624 1624 -, g dbSNP:779867285
1625 1625 -, a dbSNP:746911496
1627 1627 a, t dbSNP:756743623
1635 1635 -, tga dbSNP:768607381
1648 1648 a, c dbSNP:768147034
1651 1651 -, cac dbSNP:777855415
1657 1657 a, g dbSNP:780862528
1667 1667 a, g dbSNP:745523368
1680 1680 c, t dbSNP:755918305
1688 1688 g, t dbSNP:142577664
1705 1705 a, g dbSNP:373271688
1707 1707 c, t dbSNP:749164046
1708 1708 a, g dbSNP:768607896
1718 1718 a, g dbSNP:774205801
1724 1724 a, c, g dbSNP:148690800
1726 1726 a, g dbSNP:534500725
1731 1731 a, g dbSNP:760872306
1737 1737 a, c, g dbSNP:55726197
1738 1738 c, g dbSNP:776947297
1747 1747 a, g dbSNP:759938479
1752 1752 g, t dbSNP:765723624
1754 1754 a, g dbSNP:200407029
1755 1755 c, t dbSNP:189863121
1755 1755 -, t dbSNP:763044411
1756 1756 g, t dbSNP:369312075
1758 1758 a, c, g dbSNP:534243480
1759 1759 c, t dbSNP:373224158
1774 1774 c, t dbSNP:779894503
1775 1775 a, g dbSNP:56305733
1778 1778 c, t dbSNP:181493700
1779 1779 a, g dbSNP:754752991
1783 1783 a, t dbSNP:778843582
1789 1789 a, g dbSNP:748046504
1802 1802 -, a dbSNP:749329798
1806 1806 g, t dbSNP:768758116
1806 1806 -, t dbSNP:771104806
1809 1809 c, t dbSNP:747621119
1812 1812 a, t dbSNP:773272437
1820 1820 c, t dbSNP:747129479
1833 1833 a, t dbSNP:144599126
1844 1844 a, t dbSNP:776857506
1845 1845 c, g dbSNP:759908270
1848 1848 c, t dbSNP:765529423
1850 1850 c, t dbSNP:371392948
1853 1853 a, g dbSNP:571235425
1855 1855 g, t dbSNP:764765315
1861 1861 a, g dbSNP:749923368
1862 1862 c, g dbSNP:587778612
1878 1878 a, g dbSNP:766081471
1898 1898 c, t dbSNP:753545002
1899 1899 a, g dbSNP:754744032
1903 1903 a, c dbSNP:778557193
1907 1907 c, t dbSNP:752602525
1909 1909 a, g dbSNP:758235016
1912 1912 a, g dbSNP:777734081
1913 1913 a, g dbSNP:375640863
1914 1914 c, t dbSNP:747037734
1922 1922 a, g dbSNP:775222893
1927 1927 a, g dbSNP:1145232
1930 1930 a, t dbSNP:781328782
1933 1933 a, g dbSNP:746096258
1934 1934 a, c, t dbSNP:770115265
1966 1966 c, g dbSNP:368282144
1968 1968 c, t dbSNP:763416734
1997 1997 c, g, t dbSNP:560096410
2002 2002 c, t dbSNP:760223545
2012 2012 a, g dbSNP:56064816
2015 2015 a, g dbSNP:753446372
2025 2025 g, t dbSNP:759105195
2032 2032 c, t dbSNP:201236867
2035 2035 a, g dbSNP:151325573
2047 2047 c, t dbSNP:759894015
2049 2049 g, t dbSNP:113372387
2052 2052 c, t dbSNP:777644154
2056 2056 g, t dbSNP:751506189
2060 2060 a, c dbSNP:757273212
2063 2063 a, g dbSNP:531239757
2067 2067 -, a dbSNP:774420632
2069 2069 a, g dbSNP:61736576
2070 2070 a, g dbSNP:769876795
2085 2085 a, c dbSNP:780372372
2087 2087 a, g dbSNP:749568233
2104 2104 -, g dbSNP:759884049
2110 2110 g, t dbSNP:189785572
2111 2111 a, c, t dbSNP:774939385
2116 2116 a, g dbSNP:531589926
2118 2118 c, t dbSNP:775824945
2122 2122 c, g dbSNP:140854388
2131 2131 c, t dbSNP:201194903
2132 2132 a, g dbSNP:138610933
2134 2134 a, g dbSNP:775236748
2140 2140 a, g dbSNP:762666544
2159 2159 a, g dbSNP:768653497
2168 2168 -, ttg dbSNP:772532489
2170 2170 a, g dbSNP:74512161
2182 2182 a, c, t dbSNP:566975683
2183 2183 a, g dbSNP:750449314
2195 2195 g, t dbSNP:756240681
2196 2196 c, t dbSNP:780100887
2198 2198 c, t dbSNP:749530914
2208 2208 g, t dbSNP:755308444
2217 2217 g, t dbSNP:139552807
2218 2218 a, t dbSNP:748563735
2220 2220 a, c dbSNP:772681534
2224 2224 a, g dbSNP:773787379
2225 2225 a, g dbSNP:745326955
2226 2226 c, t dbSNP:769347993
2227 2227 a, g dbSNP:147450758
2230 2230 a, g dbSNP:762582922
2256 2256 c, g dbSNP:751603605
2259 2259 a, g dbSNP:550510753
2260 2260 c, t dbSNP:763806939
2271 2271 a, c, g dbSNP:774104441
2274 2274 a, g dbSNP:767309798
2279 2279 g, t dbSNP:145406444
2295 2295 c, g dbSNP:567568410
2296 2296 a, g dbSNP:759618103
2305 2305 c, g dbSNP:765418665
2310 2310 a, g, t dbSNP:752879348
2314 2314 c, t dbSNP:139932286
2315 2315 a, g dbSNP:751934617
2321 2321 a, g dbSNP:2066456
2328 2328 a, g dbSNP:371000056
2338 2338 a, g dbSNP:750934823
2342 2342 g, t dbSNP:754429223
2361 2361 a, g dbSNP:778382887
2379 2379 -, a dbSNP:764521118
2401 2401 a, g dbSNP:747650016
2403 2403 a, g dbSNP:771732109
2415 2415 c, t dbSNP:777313675
2435 2435 c, g dbSNP:746778101
2444 2444 c, t dbSNP:770849733
2446 2446 a, c dbSNP:374303819
2464 2464 a, g dbSNP:745785113
2482 2482 a, g dbSNP:775854930
2483 2483 c, t dbSNP:769922512
2484 2484 g, t dbSNP:587778614
2486 2486 a, t dbSNP:377266054
2490 2490 -, aag dbSNP:777263508
2503 2503 a, g dbSNP:113616678
2504 2504 a, g, t dbSNP:369814333
2523 2523 a, c dbSNP:774468225
2525 2525 c, t dbSNP:370578519
2532 2532 a, t dbSNP:374605857
2533 2533 a, g dbSNP:750847463
2536 2536 a, g dbSNP:756580931
2541 2541 -, attt dbSNP:761216715
2545 2545 -, aaaat dbSNP:764853982
2549 2549 c, t dbSNP:766919900
2560 2560 -, aaaca dbSNP:750048736
2569 2569 a, g dbSNP:752201789
2572 2572 a, g dbSNP:757877460
2580 2580 -, agaag dbSNP:758080998
2586 2586 c, g dbSNP:2066455
2588 2588 a, g dbSNP:777413446
2591 2591 a, g dbSNP:746652083
2593 2593 a, g dbSNP:61736573
2595 2595 a, g dbSNP:781127435
2599 2599 c, t dbSNP:745701071
2612 2612 a, g dbSNP:201205478
2633 2633 a, g dbSNP:368630253
2634 2634 a, g dbSNP:749351122
2645 2645 c, t dbSNP:587778613
2651 2651 c, t dbSNP:201778750
2652 2652 -, a dbSNP:766117735
2673 2673 a, t dbSNP:768622783
2675 2675 a, g dbSNP:774576220
2679 2679 a, g dbSNP:761928375
2683 2683 a, g dbSNP:767796763
2690 2690 c, g dbSNP:773542405
2696 2696 c, t dbSNP:761048343
2703 2703 a, t dbSNP:766830290
2707 2707 c, t dbSNP:754305507
2709 2709 c, t dbSNP:150341545
2710 2710 a, c dbSNP:538489643
2715 2715 g, t dbSNP:751145104
2716 2716 a, c dbSNP:375553851
2718 2718 c, t dbSNP:781043612
2725 2725 c, g dbSNP:188947672
2726 2726 c, g, t dbSNP:756008351
2736 2736 a, g dbSNP:749197166
2737 2737 a, c dbSNP:143686298
2743 2743 c, g dbSNP:778857327
2752 2752 a, g dbSNP:748274684
2756 2756 c, t dbSNP:772231922
2764 2764 a, g dbSNP:193252599
2767 2767 a, g dbSNP:201984263
2777 2777 a, g dbSNP:55680602
2779 2779 c, g dbSNP:777821897
2784 2784 c, t dbSNP:201324347
2789 2789 a, g dbSNP:553828991
2795 2795 a, t dbSNP:757396542
2796 2796 c, t dbSNP:762377532
2797 2797 a, g dbSNP:781501975
2803 2803 c, g, t dbSNP:1145234
2804 2804 a, g dbSNP:770203209
2806 2806 a, t dbSNP:776086491
2811 2811 g, t dbSNP:749800455
2814 2814 a, g dbSNP:769354925
2826 2826 a, g dbSNP:150865251
2833 2833 a, c dbSNP:760284046
2843 2843 c, g dbSNP:55859858
2846 2846 a, t dbSNP:200919195
2848 2848 c, g dbSNP:759191350
2860 2860 c, t dbSNP:371745827
2861 2861 a, g, t dbSNP:375020232
2866 2866 a, g dbSNP:200172149
2867 2867 c, g dbSNP:369226504
2868 2868 a, g dbSNP:777704189
2870 2870 c, t dbSNP:139826569
2876 2876 a, g, t dbSNP:781206054
2886 2886 a, g dbSNP:756353601
2896 2896 a, c dbSNP:587778611
2919 2919 c, t dbSNP:576339546
2922 2922 c, g dbSNP:756377066
2926 2926 g, t dbSNP:780475445
2944 2944 a, g dbSNP:369909997
2948 2948 a, g dbSNP:755396415
2960 2960 a, g dbSNP:779501477
2965 2965 -, g dbSNP:772445011
2966 2966 c, t dbSNP:199892342
2967 2967 a, g dbSNP:772517576
2981 2981 a, c dbSNP:145521752
2984 2984 c, t dbSNP:745418589
2990 2990 a, c, g, t dbSNP:56309301
2996 2996 c, t dbSNP:762670803
3002 3002 a, g dbSNP:768453779
3013 3013 a, g dbSNP:774072907
3017 3017 a, g dbSNP:761809273
3021 3021 a, t dbSNP:767398078
3029 3029 a, g dbSNP:564962629
3037 3037 c, t dbSNP:143554211
3038 3038 a, g, t dbSNP:760863069
3038 3038 -, g dbSNP:775939224
3070 3070 a, g dbSNP:374222815
3073 3073 -, a dbSNP:769123166
3073 3073 c, t dbSNP:142159998
3074 3074 -, acgc dbSNP:776982819
3074 3074 a, g dbSNP:377603311
3075 3075 a, t dbSNP:748840882
3082 3082 a, t dbSNP:754639850
3087 3087 a, g dbSNP:61748257
3088 3088 c, t dbSNP:370611400
3091 3091 c, g dbSNP:374879205
3094 3094 a, t dbSNP:537745271
3097 3097 -, tact dbSNP:762425602
3099 3099 -, tta dbSNP:764615055
3110 3110 a, g dbSNP:746934898
3115 3115 a, t dbSNP:771027683
3119 3119 a, g dbSNP:776829529
3124 3124 a, g dbSNP:759710002
3131 3131 a, g dbSNP:765457307
3136 3136 a, c dbSNP:775577121
3142 3142 c, t dbSNP:763320793
3145 3145 c, g dbSNP:775695414
3161 3161 c, t dbSNP:764353574
3178 3178 a, g dbSNP:751989008
3180 3180 c, t dbSNP:757731143
3181 3181 c, t dbSNP:145103030
3182 3182 a, g, t dbSNP:147566508
3195 3195 a, t dbSNP:778563772
3202 3202 a, g dbSNP:138906915
3205 3205 c, t dbSNP:758133616
3206 3206 a, g dbSNP:111254723
3227 3227 a, t dbSNP:746846733
3235 3235 a, t dbSNP:5743199
3238 3238 -, aag dbSNP:772733884
3240 3240 g, t dbSNP:768386630
3261 3261 g, t dbSNP:745892695
3278 3278 c, t dbSNP:774172390
3280 3280 a, g dbSNP:764216417
3285 3285 a, g dbSNP:553749816
3302 3302 -, t dbSNP:753967087
3312 3312 a, g dbSNP:761210807
3337 3337 c, t dbSNP:572013326
3363 3363 c, t dbSNP:112239654
3392 3392 c, t dbSNP:542744208
3407 3407 a, g dbSNP:562248054
3414 3414 a, c dbSNP:767117479

Target ORF information:

RefSeq Version NM_001289408
Organism Homo sapiens (human)
Definition Homo sapiens PMS1 homolog 1, mismatch repair system component (PMS1), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001289408

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGAGCTTTG GTATCCTTAA ACCTGACTTA AGGATTGTCT TTGTACATAA CAAGGCAGTT 
ATTTGGCAGA AAAGCAGAGT ATCAGATCAC AAGATGGCTC TCATGTCAGT TCTGGGGACT
GCTGTTATGA ACAATATGGA ATCCTTTCAG TACCACTCTG AAGAATCTCA GATTTATCTC
AGTGGATTTC TTCCAAAGTG TGATGCAGAC CACTCTTTCA CTAGTCTTTC AACACCAGAA
AGAAGTTTCA TCTTCATAAA CAGTCGACCA GTACATCAAA AAGATATCTT AAAGTTAATC
CGACATCATT ACAATCTGAA ATGCCTAAAG GAATCTACTC GTTTGTATCC TGTTTTCTTT
CTGAAAATCG ATGTTCCTAC AGCTGATGTT GATGTAAATT TAACACCAGA TAAAAGCCAA
GTATTATTAC AAAATAAGGA ATCTGTTTTA ATTGCTCTTG AAAATCTGAT GACGACTTGT
TATGGACCAT TACCTAGTAC AAATTCTTAT GAAAATAATA AAACAGATGT TTCCGCAGCT
GACATCGTTC TTAGTAAAAC AGCAGAAACA GATGTGCTTT TTAATAAAGT GGAATCATCT
GGAAAGAATT ATTCAAATGT TGATACTTCA GTCATTCCAT TCCAAAATGA TATGCATAAT
GATGAATCTG GAAAAAACAC TGATGATTGT TTAAATCACC AGATAAGTAT TGGTGACTTT
GGTTATGGTC ATTGTAGTAG TGAAATTTCT AACATTGATA AAAACACTAA GAATGCATTT
CAGGACATTT CAATGAGTAA TGTATCATGG GAGAACTCTC AGACGGAATA TAGTAAAACT
TGTTTTATAA GTTCCGTTAA GCACACCCAG TCAGAAAATG GCAATAAAGA CCATATAGAT
GAGAGTGGGG AAAATGAGGA AGAAGCAGGT CTTGAAAACT CTTCGGAAAT TTCTGCAGAT
GAGTGGAGCA GGGGAAATAT ACTTAAAAAT TCAGTGGGAG AGAATATTGA ACCTGTGAAA
ATTTTAGTGC CTGAAAAAAG TTTACCATGT AAAGTAAGTA ATAATAATTA TCCAATCCCT
GAACAAATGA ATCTTAATGA AGATTCATGT AACAAAAAAT CAAATGTAAT AGATAATAAA
TCTGGAAAAG TTACAGCTTA TGATTTACTT AGCAATCGAG TAATCAAGAA ACCCATGTCA
GCAAGTGCTC TTTTTGTTCA AGATCATCGT CCTCAGTTTC TCATAGAAAA TCCTAAGACT
AGTTTAGAGG ATGCAACACT ACAAATTGAA GAACTGTGGA AGACATTGAG TGAAGAGGAA
AAACTGAAAT ATGAAGAGAA GGCTACTAAA GACTTGGAAC GATACAATAG TCAAATGAAG
AGAGCCATTG AACAGGAGTC ACAAATGTCA CTAAAAGATG GCAGAAAAAA GATAAAACCC
ACCAGCGCAT GGAATTTGGC CCAGAAGCAC AAGTTAAAAA CCTCATTATC TAATCAACCA
AAACTTGATG AACTCCTTCA GTCCCAAATT GAAAAAAGAA GGAGTCAAAA TATTAAAATG
GTACAGATCC CCTTTTCTAT GAAAAACTTA AAAATAAATT TTAAGAAACA AAACAAAGTT
GACTTAGAAG AGAAGGATGA ACCTTGCTTG ATCCACAATC TCAGGTTTCC TGATGCATGG
CTAATGACAT CCAAAACAGA GGTAATGTTA TTAAATCCAT ATAGAGTAGA AGAAGCCCTG
CTATTTAAAA GACTTCTTGA GAATCATAAA CTTCCTGCAG AGCCACTGGA AAAGCCAATT
ATGTTAACAG AGAGTCTTTT TAATGGATCT CATTATTTAG ACGTTTTATA TAAAATGACA
GCAGATGACC AAAGATACAG TGGATCAACT TACCTGTCTG ATCCTCGTCT TACAGCGAAT
GGTTTCAAGA TAAAATTGAT ACCAGGAGTT TCAATTACTG AAAATTACTT GGAAATAGAA
GGAATGGCTA ATTGTCTCCC ATTCTATGGA GTAGCAGATT TAAAAGAAAT TCTTAATGCT
ATATTAAACA GAAATGCAAA GGAAGTTTAT GAATGTAGAC CTCGCAAAGT GATAAGTTAT
TTAGAGGGAG AAGCAGTGCG TCTATCCAGA CAATTACCCA TGTACTTATC AAAAGAGGAC
ATCCAAGACA TTATCTACAG AATGAAGCAC CAGTTTGGAA ATGAAATTAA AGAGTGTGTT
CATGGTCGCC CATTTTTTCA TCATTTAACC TATCTTCCAG AAACTACATG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19130
Accession Version NM_000534.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2799bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 13-JUL-2015
Organism Homo sapiens (human)
Product PMS1 protein homolog 1 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC347859.1, BC096330.1, BC096332.1 and BM677668.1. This sequence is a reference standard in the RefSeqGene project. On Jun 6, 2008 this sequence version replaced gi:53729349. Summary: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC096330.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
ATGAAACAAT TGCCTGCGGC AACAGTTCGA CTCCTTTCAA GTTCTCAGAT CATCACTTCG 
GTGGTCAGTG TTGTAAAAGA GCTTATTGAA AACTCCTTGG ATGCTGGTGC CACAAGCGTA
GATGTTAAAC TGGAGAACTA TGGATTTGAT AAAATTGAGG TGCGAGATAA CGGGGAGGGT
ATCAAGGCTG TTGATGCACC TGTAATGGCA ATGAAGTACT ACACCTCAAA AATAAATAGT
CATGAAGATC TTGAAAATTT GACAACTTAC GGTTTTCGTG GAGAAGCCTT GGGGTCAATT
TGTTGTATAG CTGAGGTTTT AATTACAACA AGAACGGCTG CTGATAATTT TAGCACCCAG
TATGTTTTAG ATGGCAGTGG CCACATACTT TCTCAGAAAC CTTCACATCT TGGTCAAGGT
ACAACTGTAA CTGCTTTAAG ATTATTTAAG AATCTACCTG TAAGAAAGCA GTTTTACTCA
ACTGCAAAAA AATGTAAAGA TGAAATAAAA AAGATCCAAG ATCTCCTCAT GAGCTTTGGT
ATCCTTAAAC CTGACTTAAG GATTGTCTTT GTACATAACA AGGCAGTTAT TTGGCAGAAA
AGCAGAGTAT CAGATCACAA GATGGCTCTC ATGTCAGTTC TGGGGACTGC TGTTATGAAC
AATATGGAAT CCTTTCAGTA CCACTCTGAA GAATCTCAGA TTTATCTCAG TGGATTTCTT
CCAAAGTGTG ATGCAGACCA CTCTTTCACT AGTCTTTCAA CACCAGAAAG AAGTTTCATC
TTCATAAACA GTCGACCAGT ACATCAAAAA GATATCTTAA AGTTAATCCG ACATCATTAC
AATCTGAAAT GCCTAAAGGA ATCTACTCGT TTGTATCCTG TTTTCTTTCT GAAAATCGAT
GTTCCTACAG CTGATGTTGA TGTAAATTTA ACACCAGATA AAAGCCAAGT ATTATTACAA
AATAAGGAAT CTGTTTTAAT TGCTCTTGAA AATCTGATGA CGACTTGTTA TGGACCATTA
CCTAGTACAA ATTCTTATGA AAATAATAAA ACAGATGTTT CCGCAGCTGA CATCGTTCTT
AGTAAAACAG CAGAAACAGA TGTGCTTTTT AATAAAGTGG AATCATCTGG AAAGAATTAT
TCAAATGTTG ATACTTCAGT CATTCCATTC CAAAATGATA TGCATAATGA TGAATCTGGA
AAAAACACTG ATGATTGTTT AAATCACCAG ATAAGTATTG GTGACTTTGG TTATGGTCAT
TGTAGTAGTG AAATTTCTAA CATTGATAAA AACACTAAGA ATGCATTTCA GGACATTTCA
ATGAGTAATG TATCATGGGA GAACTCTCAG ACGGAATATA GTAAAACTTG TTTTATAAGT
TCCGTTAAGC ACACCCAGTC AGAAAATGGC AATAAAGACC ATATAGATGA GAGTGGGGAA
AATGAGGAAG AAGCAGGTCT TGAAAACTCT TCGGAAATTT CTGCAGATGA GTGGAGCAGG
GGAAATATAC TTAAAAATTC AGTGGGAGAG AATATTGAAC CTGTGAAAAT TTTAGTGCCT
GAAAAAAGTT TACCATGTAA AGTAAGTAAT AATAATTATC CAATCCCTGA ACAAATGAAT
CTTAATGAAG ATTCATGTAA CAAAAAATCA AATGTAATAG ATAATAAATC TGGAAAAGTT
ACAGCTTATG ATTTACTTAG CAATCGAGTA ATCAAGAAAC CCATGTCAGC AAGTGCTCTT
TTTGTTCAAG ATCATCGTCC TCAGTTTCTC ATAGAAAATC CTAAGACTAG TTTAGAGGAT
GCAACACTAC AAATTGAAGA ACTGTGGAAG ACATTGAGTG AAGAGGAAAA ACTGAAATAT
GAAGAGAAGG CTACTAAAGA CTTGGAACGA TACAATAGTC AAATGAAGAG AGCCATTGAA
CAGGAGTCAC AAATGTCACT AAAAGATGGC AGAAAAAAGA TAAAACCCAC CAGCGCATGG
AATTTGGCCC AGAAGCACAA GTTAAAAACC TCATTATCTA ATCAACCAAA ACTTGATGAA
CTCCTTCAGT CCCAAATTGA AAAAAGAAGG AGTCAAAATA TTAAAATGGT ACAGATCCCC
TTTTCTATGA AAAACTTAAA AATAAATTTT AAGAAACAAA ACAAAGTTGA CTTAGAAGAG
AAGGATGAAC CTTGCTTGAT CCACAATCTC AGGTTTCCTG ATGCATGGCT AATGACATCC
AAAACAGAGG TAATGTTATT AAATCCATAT AGAGTAGAAG AAGCCCTGCT ATTTAAAAGA
CTTCTTGAGA ATCATAAACT TCCTGCAGAG CCACTGGAAA AGCCAATTAT GTTAACAGAG
AGTCTTTTTA ATGGATCTCA TTATTTAGAC GTTTTATATA AAATGACAGC AGATGACCAA
AGATACAGTG GATCAACTTA CCTGTCTGAT CCTCGTCTTA CAGCGAATGG TTTCAAGATA
AAATTGATAC CAGGAGTTTC AATTACTGAA AATTACTTGG AAATAGAAGG AATGGCTAAT
TGTCTCCCAT TCTATGGAGT AGCAGATTTA AAAGAAATTC TTAATGCTAT ATTAAACAGA
AATGCAAAGG AAGTTTATGA ATGTAGACCT CGCAAAGTGA TAAGTTATTT AGAGGGAGAA
GCAGTGCGTC TATCCAGACA ATTACCCATG TACTTATCAA AAGAGGACAT CCAAGACATT
ATCTACAGAA TGAAGCACCA GTTTGGAAAT GAAATTAAAG AGTGTGTTCA TGGTCGCCCA
TTTTTTCATC ATTTAACCTA TCTTCCAGAA ACTACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_000525.1
CDS530..3328
Misc Feature(1)366..366(+)
Misc Feature(2)401..401(+)
Misc Feature(3)412..412(+)
Misc Feature(4)476..476(+)
Misc Feature(5)500..502(+)
Misc Feature(6)530..1483(+)
Misc Feature(7)596..>832(+)
Misc Feature(8)608..820(+)
Misc Feature(9)620..622(+)
Misc Feature(10)701..817(+)
Misc Feature(11)1142..1543(+)
Misc Feature(12)1469..1471(+)
Misc Feature(13)2243..2437(+)
Misc Feature(14)2246..2413(+)
Exon (1)1..509
Gene:PMS1
Gene Synonym:
Exon (2)510..661
Gene:PMS1
Gene Synonym:
Exon (3)662..844
Gene:PMS1
Gene Synonym:
Exon (4)845..947
Gene:PMS1
Gene Synonym:
Exon (5)948..1111
Gene:PMS1
Gene Synonym:
Exon (6)1112..1228
Gene:PMS1
Gene Synonym:
Exon (7)1229..1351
Gene:PMS1
Gene Synonym:
Exon (8)1352..1495
Gene:PMS1
Gene Synonym:
Exon (9)1496..2385
Gene:PMS1
Gene Synonym:
Exon (10)2386..2871
Gene:PMS1
Gene Synonym:
Exon (11)2872..3002
Gene:PMS1
Gene Synonym:
Exon (12)3003..3163
Gene:PMS1
Gene Synonym:
Exon (13)3164..3521
Gene:PMS1
Gene Synonym:
Translation
Position Chain Variation Link
20 20 a, g dbSNP:189547607
22 22 a, g dbSNP:536962444
23 23 c, t dbSNP:554655433
34 34 c, g dbSNP:750021361
41 41 a, g dbSNP:576428024
49 49 a, g dbSNP:5742927
53 53 c, g dbSNP:565412237
60 60 c, t dbSNP:757816314
70 70 c, t dbSNP:577428807
74 74 c, g dbSNP:11550049
89 89 g, t dbSNP:541196484
96 96 c, t dbSNP:559590295
137 137 a, c, g dbSNP:369675358
139 139 a, c dbSNP:529904737
175 175 a, g dbSNP:548513402
187 187 a, g dbSNP:5742928
194 194 c, t dbSNP:372712876
200 200 g, t dbSNP:758067747
207 207 c, t dbSNP:777624544
228 228 c, t dbSNP:5742929
232 232 g, t dbSNP:746616111
246 246 a, c dbSNP:551774070
250 250 a, c dbSNP:5742930
255 255 c, t dbSNP:5742931
256 256 a, t dbSNP:534415170
264 264 a, g dbSNP:547545719
271 271 a, c dbSNP:566304104
290 290 a, c dbSNP:536540364
296 296 c, t dbSNP:756536859
298 298 g, t dbSNP:745440258
350 350 c, g dbSNP:555270776
366 366 a, g dbSNP:777937194
371 371 c, t dbSNP:576342227
374 374 a, g dbSNP:147002700
380 380 c, t dbSNP:749530064
386 386 a, c, g dbSNP:375594683
409 409 -, gggtgc dbSNP:766501073
410 410 a, g dbSNP:757537327
422 422 c, g dbSNP:779071853
424 424 a, g dbSNP:556452424
427 427 c, t dbSNP:745993205
430 430 g, t dbSNP:5742932
431 431 g, t dbSNP:577363454
442 442 a, g dbSNP:541545004
446 446 c, g, t dbSNP:374103918
454 454 a, g dbSNP:559588204
483 483 a, g dbSNP:574605931
504 504 a, c dbSNP:771993432
506 506 c, g dbSNP:5742933
514 514 c, t dbSNP:757794123
515 515 c, t dbSNP:781605412
525 525 c, t dbSNP:570050132
526 526 a, g dbSNP:754586160
538 538 a, g dbSNP:373031044
540 540 c, t dbSNP:201944922
544 544 c, t dbSNP:778660303
546 546 c, t dbSNP:747835603
547 547 a, g dbSNP:771930754
551 551 a, g dbSNP:777641087
558 558 a, g dbSNP:370084230
561 561 c, t dbSNP:770894099
562 562 c, t dbSNP:762260830
563 563 a, c, t dbSNP:374261058
569 569 a, g dbSNP:775649361
570 570 a, g dbSNP:763166242
574 574 a, t dbSNP:377616727
576 576 a, g dbSNP:570876790
578 578 a, g dbSNP:151231718
585 585 c, g dbSNP:534847551
588 588 c, t dbSNP:768047966
589 589 g, t dbSNP:750916185
592 592 g, t dbSNP:754498304
599 599 a, g dbSNP:553130827
608 608 c, g dbSNP:5742973
635 635 a, g dbSNP:781053212
642 642 -, caagcg dbSNP:761879899
643 643 a, t dbSNP:758112220
644 644 a, g dbSNP:113193813
646 646 c, t dbSNP:777358818
647 647 a, g dbSNP:746784366
650 650 c, g dbSNP:757048301
651 651 a, c, g dbSNP:545600556
655 655 g, t dbSNP:769797470
669 669 a, g dbSNP:756031414
670 670 c, t dbSNP:5742980
681 681 a, c dbSNP:370668897
692 692 c, t dbSNP:375147123
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