The following FGFRL1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FGFRL1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||Documents for ORF clone product in dufault vector
||ORF Nucleotide Sequence (Length: 1515bp)
||pcDNA3.1+/C-(K)DYK or customized vector
||Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
||Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Document: OHu03560D_COA.pdf (pdf)
||Homo sapiens (human)
||fibroblast growth factor receptor-like 1 precursor
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AJ277437.1, BC036769.1 and
On Sep 13, 2004 this sequence version replaced gi:13112053.
Summary: The protein encoded by this gene is a member of the
fibroblast growth factor receptor (FGFR) family, where amino acid
sequence is highly conserved between members and throughout
evolution. FGFR family members differ from one another in their
ligand affinities and tissue distribution. A full-length
representative protein would consist of an extracellular region,
composed of three immunoglobulin-like domains, a single hydrophobic
membrane-spanning segment and a cytoplasmic tyrosine kinase domain.
The extracellular portion of the protein interacts with fibroblast
growth factors, setting in motion a cascade of downstream signals,
ultimately influencing mitogenesis and differentiation. A marked
difference between this gene product and the other family members
is its lack of a cytoplasmic tyrosine kinase domain. The result is
a transmembrane receptor that could interact with other family
members and potentially inhibit signaling. Multiple alternatively
spliced transcript variants encoding the same isoform have been
found for this gene. [provided by RefSeq, Jul 2008].
Transcript Variant: This variant (3) has an alternate 5' UTR, and
encodes the same isoform, as compared to variant 1.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: AJ277437.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.