TOMM7 cDNA ORF clone, Homo sapiens (human)

Gene Symbol TOMM7
Entrez Gene ID 54543
Full Name translocase of outer mitochondrial membrane 7 homolog (yeast)
Synonyms TOM7
General protein information
Preferred Names
mitochondrial import receptor subunit TOM7 homolog
mitochondrial import receptor subunit TOM7 homolog
6.2 kd protein
translocase of outer membrane 7 kDa subunit homolog
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene encodes a subunit of the translocase of the outer mitochondrial membrane. The encoded protein regulates the assembly and stability of the translocase complex. [provided by RefSeq, Oct 2012]. lac of sum
Disorder MIM:


Disorder Html:

mRNA and Protein(s)

mRNA Protein Name
NM_019059 NP_061932 mitochondrial import receptor subunit TOM7 homolog

R-HSA-392499 Metabolism of proteins
R-HSA-1268020 Mitochondrial protein import

Homo sapiens (human) TOMM7 NP_061932.1
Pan troglodytes (chimpanzee) TOMM7 XP_001153870.2
Macaca mulatta (Rhesus monkey) TOMM7 XP_001102062.1
Canis lupus familiaris (dog) TOMM7 XP_539468.3
Bos taurus (cattle) TOMM7 NP_001106777.1
Mus musculus (house mouse) Tomm7 NP_079670.1
Rattus norvegicus (Norway rat) Tomm7 NP_001128646.1
Gallus gallus (chicken) TOMM7 NP_001186546.1


ID Name Evidence
GO:0005739 mitochondrion IDA
GO:0005742 mitochondrial outer membrane translocase complex IDA
GO:0016020 membrane IEA
GO:0016021 integral to membrane IEA


ID Name Evidence
GO:0008320 protein transmembrane transporter activity TAS
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity IEA


ID Name Evidence
GO:0006626 protein targeting to mitochondrion TAS
GO:0006886 intracellular protein transport IEA

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following TOMM7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TOMM7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
NM_019059 Homo sapiens translocase of outer mitochondrial membrane 7 homolog (yeast) (TOMM7), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee that the protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

CloneID OHu11238
Accession Version NM_019059.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 168bp)
Protein sequence
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product mitochondrial import receptor subunit TOM7 homolog
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AA181858.1, BC071973.1, BC001732.1 and AC005682.2. On Oct 24, 2012 this sequence version replaced gi:48976049. Summary: This gene encodes a subunit of the translocase of the outer mitochondrial membrane. The encoded protein regulates the assembly and stability of the translocase complex. [provided by RefSeq, Oct 2012]. ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: BC071973.1, BM761830.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##


The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

Misc Feature(1)98..232(+)
Misc Feature(2)134..181(+)
Exon (1)1..176
Gene Synonym:
Exon (2)177..225
Gene Synonym:
Exon (3)226..779
Gene Synonym:
Position Chain Variation Link
5 5 c, t dbSNP:2270105
10 10 c, t dbSNP:555489915
23 23 c, g dbSNP:754331737
26 26 c, g dbSNP:375208814
29 29 c, t dbSNP:760781520
31 31 c, t dbSNP:773432962
37 37 c, t dbSNP:772348183
43 43 c, g dbSNP:371820988
45 45 a, g dbSNP:774482209
48 48 a, c dbSNP:769597222
49 49 c, g dbSNP:745677965
54 54 g, t dbSNP:781132656
55 55 a, g dbSNP:369337116
59 59 c, t dbSNP:770866576
64 64 a, g dbSNP:374907365
66 66 c, t dbSNP:530787392
67 67 c, t dbSNP:779018097
68 68 a, g dbSNP:777260166
72 72 a, c dbSNP:757962007
73 73 c, t dbSNP:747805671
77 77 -, gtgaagctg dbSNP:778885601
82 82 g, t dbSNP:778462898
97 97 c, g, t dbSNP:754831020
99 99 a, g dbSNP:754168840
100 100 a, g dbSNP:766928879
102 102 a, g dbSNP:756687946
105 105 c, g dbSNP:140701464
109 109 a, g dbSNP:147233774
110 110 c, t dbSNP:761835937
113 113 c, t dbSNP:774588880
123 123 a, c dbSNP:764242809
124 124 a, g dbSNP:267601461
130 130 c, t dbSNP:759315830
132 132 a, g dbSNP:528247553
138 138 c, t dbSNP:770778580
139 139 c, t dbSNP:746935829
144 144 a, g dbSNP:773174244
155 155 a, c dbSNP:771572545
157 157 c, t dbSNP:149563394
159 159 c, t dbSNP:778567973
160 160 c, t dbSNP:138312355
161 161 c, t dbSNP:754589475
172 172 c, t dbSNP:749032737
188 188 c, g dbSNP:765466330
192 192 c, t dbSNP:368578088
194 194 g, t dbSNP:750797740
197 197 c, g dbSNP:750221280
199 199 c, t dbSNP:141512738
200 200 a, g dbSNP:138988156
206 206 c, g dbSNP:774391125
211 211 a, c dbSNP:144665947
212 212 c, g dbSNP:779983228
215 215 a, c dbSNP:775237725
216 216 c, t dbSNP:142415106
245 245 a, t dbSNP:772570431
251 251 g, t dbSNP:748718417
255 255 c, g dbSNP:778948787
256 256 c, t dbSNP:755096940
273 273 a, g dbSNP:368421212
274 274 g, t dbSNP:780351479
278 278 c, t dbSNP:570562210
279 279 a, g dbSNP:201378474
280 280 a, g dbSNP:764059947
288 288 a, g dbSNP:758408755
294 294 c, t dbSNP:752742258
300 300 c, g dbSNP:556430590
306 306 c, g dbSNP:759158918
308 308 c, g, t dbSNP:766068357
309 309 a, g dbSNP:760881080
320 320 c, g dbSNP:773620062
329 329 -, ttca dbSNP:777088136
333 333 c, g dbSNP:772482122
335 335 c, g dbSNP:748630230
337 337 c, t dbSNP:774874509
339 339 a, g dbSNP:768678749
340 340 a, g dbSNP:749412166
344 344 a, g dbSNP:780084548
353 353 a, g dbSNP:762199420
356 356 c, t dbSNP:536910931
361 361 -, c dbSNP:766607637
361 361 c, t dbSNP:746145865
367 367 c, t dbSNP:567868758
386 386 a, t dbSNP:3087676
386 386 a, c dbSNP:539986954
387 387 a, t dbSNP:1054471
438 438 a, t dbSNP:113219383
439 439 a, t dbSNP:111824691
447 447 a, g dbSNP:753406781
459 459 a, g dbSNP:765866585
489 489 -, ttaa dbSNP:773180800
494 494 c, t dbSNP:571352088
518 518 a, g dbSNP:2240727
531 531 a, g dbSNP:2240728
554 554 c, g dbSNP:568910082
594 594 c, t dbSNP:77893681
606 606 a, t dbSNP:112599404
634 634 c, t dbSNP:770575885
650 650 c, g dbSNP:746466670
677 677 c, t dbSNP:560208764
679 679 c, t dbSNP:546738974
684 684 c, t dbSNP:777882761
691 691 c, t dbSNP:370611001
694 694 c, t dbSNP:752586113
778 778 a, t dbSNP:565036422

Target ORF information:

RefSeq Version NM_019059
Organism Homo sapiens (human)
Definition Homo sapiens translocase of outer mitochondrial membrane 7 homolog (yeast) (TOMM7), mRNA.

Target ORF information:

Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK

ORF Insert Sequence:


The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.


Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease
Circulation 128 (12), 1310-1324 (2013)
Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP, Folkersen L, Basu S, Rudnicka AR, Trompet S, Malarstig A, Baumert J, Bis JC, Guo X, Hottenga JJ, Shin SY, Lopez LM, Lahti J, Tanaka T, Yanek LR, Oudot-Mellakh T, Wilson JF, Navarro P, Huffman JE, Zemunik T, Redline S, Mehra R, Pulanic D, Rudan I, Wright AF, Kolcic I, Polasek O, Wild SH, Campbell H, Curb JD, Wallace R, Liu S, Eaton CB, Becker DM, Becker LC, Bandinelli S, Raikkonen K, Widen E, Palotie A, Fornage M, Green D, Gross M, Davies G, Harris SE, Liewald DC, Starr JM, Williams FM, Grant PJ, Spector TD, Strawbridge RJ, Silveira A, Sennblad B, Rivadeneira F, Uitterlinden AG, Franco OH, Hofman A, van Dongen J, Willemsen G, Boomsma DI, Yao J, Swords Jenny N, Haritunians T, McKnight B, Lumley T, Taylor KD, Rotter JI, Psaty BM, Peters A, Gieger C, Illig T, Grotevendt A, Homuth G, Volzke H, Kocher T, Goel A, Franzosi MG, Seedorf U, Clarke R, Steri M, Tarasov KV, Sanna S, Schlessinger D, Stott DJ, Sattar N, Buckley BM, Rumley A, Lowe GD, McArdle WL, Chen MH, Tofler GH, Song J, Boerwinkle E, Folsom AR, Rose LM, Franco-Cereceda A, Teichert M, Ikram MA, Mosley TH, Bevan S, Dichgans M, Rothwell PM, Sudlow CL, Hopewell JC, Chambers JC, Saleheen D, Kooner JS, Danesh J, Nelson CP, Erdmann J, Reilly MP, Kathiresan S, Schunkert H, Morange PE, Ferrucci L, Eriksson JG, Jacobs D, Deary IJ, Soranzo N, Witteman JC, de Geus EJ, Tracy RP, Hayward C, Koenig W, Cucca F, Jukema JW, Eriksson P, Seshadri S, Markus HS, Watkins H, Samani NJ, Wallaschofski H, Smith NL, Tregouet D, Ridker PM, Tang W, Strachan DP, Hamsten A and O'Donnell CJ.


Identification of Tom5 and Tom6 in the preprotein translocase complex of human mitochondrial outer membrane
Biochem. Biophys. Res. Commun. 369 (3), 958-963 (2008)
Kato H and Mihara K.


Dissection of the mitochondrial import and assembly pathway for human Tom40
J. Biol. Chem. 280 (12), 11535-11543 (2005)
Humphries AD, Streimann IC, Stojanovski D, Johnston AJ, Yano M, Hoogenraad NJ and Ryan MT.


Insertion and assembly of human tom7 into the preprotein translocase complex of the outer mitochondrial membrane
J. Biol. Chem. 277 (44), 42197-42204 (2002)
Johnston AJ, Hoogenraad J, Dougan DA, Truscott KN, Yano M, Mori M, Hoogenraad NJ and Ryan MT.


Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning
Proc. Natl. Acad. Sci. U.S.A. 97 (17), 9543-9548 (2000)
Hu RM, Han ZG, Song HD, Peng YD, Huang QH, Ren SX, Gu YJ, Huang CH, Li YB, Jiang CL, Fu G, Zhang QH, Gu BW, Dai M, Mao YF, Gao GF, Rong R, Ye M, Zhou J, Xu SH, Gu J, Shi JX, Jin WR, Zhang CK, Wu TM, Huang GY, Chen Z, Chen MD and Chen JL.


Cloning and characterization of the human novel gene encoding 6.2 kDa protein highly expressed upon ultraviolet irradiation in DNA-PK-deleted human glioma M059J cells
DNA Seq. 10 (3), 195-198 (1999)
Lee JS.