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POU3F3 POU class 3 homeobox 3 [Homo sapiens (human)]

Gene Symbol POU3F3
Entrez Gene ID 5455
Full Name POU class 3 homeobox 3
Synonyms BRN1, OTF8, brain-1, oct-8
General protein information
Preferred Names
POU domain, class 3, transcription factor 3
Names
POU domain, class 3, transcription factor 3
OTF-8
brn-1
oct-8
brain-1
octamer-binding protein 8
octamer-binding transcription factor 8
brain-specific homeobox/POU domain protein 1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2q12.1

Summary This gene encodes a POU-domain containing protein that functions as a transcription factor. The encoded protein recognizes an octamer sequence in the DNA of target genes. This protein may play a role in development of the nervous system. [provided by RefSeq, Apr 2015]. lac of sum
Disorder MIM:

602480

Disorder Html:





The following POU3F3 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the POU3F3 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu30942 NM_006236 Homo sapiens POU class 3 homeobox 3 (POU3F3), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $419

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu30942
Accession Version NM_006236.2
Sequence Information ORF Nucleotide Sequence (Length: 1503bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 03-APR-2015
Organism Homo sapiens (human)
Product POU domain, class 3, transcription factor 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC018730.8, CX873380.1 and CX873394.1. On Apr 3, 2015 this sequence version replaced gi:5453935. Summary: This gene encodes a POU-domain containing protein that functions as a transcription factor. The encoded protein recognizes an octamer sequence in the DNA of target genes. This protein may play a role in development of the nervous system. [provided by RefSeq, Apr 2015]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGCCACGG CGGCTTCTAA CCCCTACCTG CCGGGGAACA GCCTGCTCGC GGCCGGCTCT 
ATTGTGCACT CGGACGCGGC AGGGGCTGGC GGCGGCGGGG GTGGCGGCGG CGGCGGCGGC
GGGGGCGGCG CAGGGGGCGG GGGCGGCGGC ATGCAGCCGG GCAGCGCCGC CGTGACCTCG
GGCGCCTACC GGGGGGACCC GTCCTCTGTC AAGATGGTCC AGAGCGACTT CATGCAGGGG
GCCATGGCCG CCAGCAACGG CGGCCATATG CTGAGCCACG CGCACCAGTG GGTCACAGCC
CTGCCCCACG CCGCCGCCGC CGCCGCCGCT GCCGCCGCCG CCGCCGTGGA GGCGAGCTCG
CCGTGGTCGG GCAGCGCCGT GGGCATGGCT GGCAGCCCCC AGCAGCCACC GCAGCCGCCG
CCGCCACCGC CGCAGGGCCC CGACGTGAAG GGCGGCGCCG GGCGCGACGA CCTGCACGCG
GGCACAGCGC TGCACCACCG CGGGCCGCCG CACCTCGGAC CCCCGCCGCC GCCCCCACAC
CAGGGCCACC CTGGGGGCTG GGGGGCGGCC GCCGCTGCCG CAGCCGCAGC CGCCGCCGCC
GCCGCCGCCG CGCACCTCCC GTCCATGGCC GGGGGCCAGC AGCCGCCGCC GCAGAGTCTG
CTCTACTCGC AGCCCGGAGG CTTCACGGTG AACGGCATGC TGAGCGCGCC ACCGGGGCCC
GGCGGCGGCG GCGGCGGCGC GGGCGGTGGA GCCCAGAGCT TGGTGCACCC GGGGCTGGTG
CGCGGGGACA CGCCAGAGCT GGCCGAGCAC CACCACCACC ACCACCACCA CGCGCATCCT
CACCCGCCGC ACCCGCACCA CGCGCAGGGA CCCCCGCACC ACGGCGGCGG CGGCGGCGGC
GCGGGGCCTG GACTCAACAG CCACGACCCG CACTCGGACG AGGACACGCC GACGTCGGAC
GACCTGGAGC AGTTCGCCAA GCAGTTCAAG CAGCGGCGCA TCAAGCTGGG CTTCACGCAG
GCCGACGTGG GGTTGGCGCT GGGCACACTC TACGGCAACG TGTTCTCGCA GACCACCATC
TGCCGCTTCG AGGCCCTGCA GCTGAGCTTC AAGAACATGT GCAAGCTCAA GCCGCTGCTG
AACAAGTGGC TGGAGGAGGC GGACTCAAGC ACCGGCAGCC CCACAAGCAT CGACAAGATC
GCGGCGCAGG GCCGCAAGCG CAAGAAGCGG ACCTCTATCG AGGTGAGCGT CAAGGGCGCG
CTGGAGAGCC ACTTCCTCAA GTGCCCCAAG CCCTCCGCGC AGGAGATCAC CAACCTGGCC
GACAGCCTGC AGCTCGAGAA GGAGGTGGTG CGGGTCTGGT TCTGCAATCG GCGCCAAAAG
GAGAAGCGCA TGACGCCGCC CGGGATCCAA CAGCAGACGC CCGACGACGT CTACTCGCAG
GTGGGCACCG TGAGCGCCGA CACGCCGCCG CCTCACCACG GGCTGCAGAC GAGCGTTCAG
TGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_006227.1
CDS1444..2946
Misc Feature(1)889..891(+)
Misc Feature(2)2383..2607(+)
Misc Feature(3)2662..2835(+)
Misc Feature(4)2662..2832(+)
Misc Feature(5)2668..2820(+)
Exon (1)1..4507
Gene:POU3F3
Gene Synonym:
Translation
Position Chain Variation Link
13 13 a, t dbSNP:765311210
53 53 a, g dbSNP:754507182
97 97 a, t dbSNP:114510536
98 98 a, c, t dbSNP:527363620
118 118 c, g dbSNP:369599926
135 135 c, g dbSNP:549199613
151 151 a, c, g, t dbSNP:199515144
164 164 a, g dbSNP:567749273
180 180 c, g dbSNP:367605890
218 218 a, g dbSNP:550210742
236 236 g, t dbSNP:141819628
258 258 a, g dbSNP:539052004
337 337 c, t dbSNP:373623668
362 362 c, t dbSNP:778245430
439 439 c, g dbSNP:554183150
448 448 c, t dbSNP:77739424
473 473 a, g dbSNP:747260097
492 492 c, t dbSNP:146061121
591 591 a, t dbSNP:536732764
592 592 a, c dbSNP:555581056
609 609 g, t dbSNP:371697457
610 610 c, g dbSNP:745989925
639 639 c, t dbSNP:769892515
659 659 c, g dbSNP:186310432
695 695 a, g dbSNP:774310504
718 718 c, t dbSNP:190793769
745 745 c, t dbSNP:114716398
777 777 -, gagga dbSNP:767356487
781 781 -, gaggagagga dbSNP:762777001
785 785 a, g dbSNP:533174142
822 822 c, t dbSNP:751968570
827 827 c, t dbSNP:551459624
867 867 c, t dbSNP:577486145
889 889 c, t dbSNP:544632860
914 914 a, g dbSNP:559701743
915 915 g, t dbSNP:527425540
927 927 a, c dbSNP:140062057
928 928 a, g dbSNP:760380096
945 945 g, t dbSNP:781555042
972 972 c, t dbSNP:3739155
1011 1011 a, g dbSNP:770287087
1048 1048 c, t dbSNP:531823186
1124 1124 g, t dbSNP:779743162
1126 1126 c, g dbSNP:550316934
1199 1199 a, g dbSNP:113189120
1409 1409 g, t dbSNP:182220950
1419 1419 c, g dbSNP:565463018
1421 1421 g, t dbSNP:532835644
1464 1464 c, t dbSNP:762770245
1488 1488 a, g dbSNP:764013027
1530 1530 c, t dbSNP:186512421
1533 1533 c, t dbSNP:756985681
1545 1545 g, t dbSNP:547848317
1548 1548 c, g dbSNP:566074819
1590 1590 a, c, t dbSNP:766929905
1600 1600 c, t dbSNP:755592572
1621 1621 g, t dbSNP:779410764
1624 1624 a, g dbSNP:748681422
1633 1633 a, c, g dbSNP:758709883
1636 1636 c, g dbSNP:747198984
1637 1637 c, g dbSNP:771253910
1638 1638 g, t dbSNP:776563157
1639 1639 a, c, g dbSNP:745905442
1643 1643 c, g dbSNP:375481587
1651 1651 a, g dbSNP:763007366
1667 1667 a, g dbSNP:763960008
1669 1669 a, g dbSNP:774329985
1671 1671 c, t dbSNP:536599645
1676 1676 c, t dbSNP:767139571
1684 1684 a, g, t dbSNP:750047437
1686 1686 a, c, t dbSNP:765892800
1692 1692 c, t dbSNP:758940906
1704 1704 c, t dbSNP:778104691
1709 1709 a, g dbSNP:747467083
1725 1725 g, t dbSNP:757579144
1728 1728 a, c dbSNP:781413853
1749 1749 c, t dbSNP:746108918
1751 1751 -, cgc, cgccgc dbSNP:765534543
1752 1752 -, cgccgccgccgc dbSNP:754300848
1752 1752 -, cgccgccgc dbSNP:763521605
1752 1752 -, cgc dbSNP:760290191
1765 1765 -, gccgccgct dbSNP:747214163
1768 1768 -, gccgct dbSNP:755018949
1770 1770 c, t dbSNP:769870078
1774 1774 -, gcc dbSNP:781161822
1788 1788 -, cgt dbSNP:749189956
1803 1803 g, t dbSNP:191591917
1857 1857 -, gcc dbSNP:771043661
1861 1861 -, ccgccgcca dbSNP:774254585
1872 1872 a, g dbSNP:780332172
1944 1944 a, c dbSNP:749208505
1991 1991 a, c dbSNP:548400700
1995 1995 g, t dbSNP:570097332
2020 2020 -, gccgca dbSNP:745723608
2031 2031 -, gccgcc dbSNP:771609174
2031 2031 a, c dbSNP:768770377
2032 2032 -, gcc dbSNP:775150602
2124 2124 a, c dbSNP:774442521
2130 2130 c, g dbSNP:761600759
2163 2163 -, cggcggcgg dbSNP:763616750
2163 2163 -, cgg dbSNP:542802090
2181 2181 c, g dbSNP:537665161
2190 2190 g, t dbSNP:556300585
2217 2217 a, g dbSNP:368850481
2226 2226 c, t dbSNP:771794797
2250 2250 -, cac dbSNP:762283249
2251 2251 -, cac dbSNP:776137937
2277 2277 g, t dbSNP:772868054
2289 2289 c, g dbSNP:760289602
2295 2295 c, t dbSNP:765841252
2298 2298 a, g dbSNP:753410679
2316 2316 c, g, t dbSNP:763440005
2318 2318 a, c dbSNP:752015441
2321 2321 a, c dbSNP:757606116
2324 2324 -, acggcg dbSNP:765802779
2324 2324 -, cgg, cggcgg dbSNP:758735626
2325 2325 -, cggcggcgg dbSNP:550439793
2325 2325 -, cggcgg dbSNP:751766792
2325 2325 -, cgg dbSNP:750777878
2326 2326 a, g dbSNP:577550493
2333 2333 -, cgg dbSNP:546400611
2337 2337 c, g, t dbSNP:372442573
2346 2346 c, g dbSNP:750637952
2348 2348 a, g dbSNP:756446613
2349 2349 a, g dbSNP:780279142
2363 2363 c, g dbSNP:749320929
2364 2364 a, c, t dbSNP:768860277
2370 2370 c, t dbSNP:748058450
2371 2371 c, g dbSNP:771875028
2372 2372 a, c dbSNP:772917640
2373 2373 a, g dbSNP:760368081
2391 2391 a, g dbSNP:770625428
2394 2394 c, g dbSNP:572675410
2415 2415 a, g dbSNP:182992623
2418 2418 c, t dbSNP:758983648
2427 2427 a, g dbSNP:764762195
2437 2437 a, c dbSNP:571710580
2439 2439 a, g dbSNP:377053693
2487 2487 -, ca dbSNP:748780387
2490 2490 a, c dbSNP:762277417
2493 2493 c, t dbSNP:767894321
2505 2505 a, g dbSNP:371621473
2514 2514 a, g dbSNP:756558999
2520 2520 c, t dbSNP:780354913
2523 2523 c, t dbSNP:754144331
2529 2529 c, t dbSNP:755059340
2550 2550 c, t dbSNP:778904576
2556 2556 a, g dbSNP:748084015
2559 2559 c, t dbSNP:758331254
2577 2577 c, g dbSNP:777608264
2597 2597 a, g dbSNP:746751751
2600 2600 a, g dbSNP:770719599
2601 2601 a, g dbSNP:776229188
2604 2604 a, g dbSNP:745546456
2616 2616 c, t dbSNP:199565525
2618 2618 a, g dbSNP:774903968
2622 2622 c, t dbSNP:140419524
2626 2626 a, g dbSNP:767968798
2629 2629 a, g dbSNP:773772879
2630 2630 c, g dbSNP:146486201
2643 2643 c, t dbSNP:143105467
2644 2644 g, t dbSNP:766869344
2649 2649 a, c, g dbSNP:140129722
2658 2658 c, g dbSNP:137877846
2664 2664 c, g dbSNP:372764445
2673 2673 a, g dbSNP:758516234
2682 2682 a, c dbSNP:777507294
2711 2711 c, g dbSNP:746982147
2712 2712 c, t dbSNP:756997559
2718 2718 c, t dbSNP:377188135
2752 2752 a, t dbSNP:745493142
2754 2754 c, t dbSNP:769403407
2758 2758 c, t dbSNP:775054761
2765 2765 a, g dbSNP:748677714
2768 2768 a, c, g dbSNP:768241893
2779 2779 c, g dbSNP:761309325
2790 2790 a, g dbSNP:147315122
2844 2844 c, t dbSNP:777201991
2865 2865 a, c, g, t dbSNP:759817331
2868 2868 a, c dbSNP:758371926
2869 2869 a, g dbSNP:764256978
2871 2871 c, g dbSNP:751477427
2873 2873 a, t dbSNP:377514724
2880 2880 a, g dbSNP:780965214
2883 2883 a, g dbSNP:750280176
2897 2897 a, g dbSNP:755952227
2901 2901 a, c dbSNP:779530854
2902 2902 a, g dbSNP:576061892
2907 2907 c, g dbSNP:768025847
2914 2914 c, t dbSNP:778602880
2916 2916 a, t dbSNP:202016096
2928 2928 a, g dbSNP:374340255
2931 2931 a, g dbSNP:777289770
2933 2933 c, g dbSNP:759751110
2934 2934 g, t dbSNP:770227812
2943 2943 g, t dbSNP:775527775
2948 2948 a, g, t dbSNP:763285090
2951 2951 a, t dbSNP:751709007
2954 2954 a, g dbSNP:113920817
2956 2956 a, g dbSNP:200554113
2963 2963 a, g dbSNP:767387977
2969 2969 -, gcc, gccgcc dbSNP:748277563
2970 2970 -, gccgcc dbSNP:781311964
2970 2970 -, gcc dbSNP:779050745
2970 2970 c, g dbSNP:750388843
2971 2971 c, t dbSNP:755813141
2979 2979 a, g dbSNP:532899619
2982 2982 -, ccgcct dbSNP:771830063
2982 2982 a, g dbSNP:753397035
2984 2984 a, c dbSNP:754725748
2993 2993 a, c dbSNP:778552073
3032 3032 c, t dbSNP:771781140
3050 3050 c, t dbSNP:548108972
3057 3057 a, g dbSNP:560044906
3138 3138 a, g dbSNP:546349728
3173 3173 g, t dbSNP:732278
3257 3257 a, g dbSNP:576425353
3264 3264 a, g dbSNP:370409837
3330 3330 -, t dbSNP:367709255
3330 3330 -, g dbSNP:548836960
3342 3342 g, t dbSNP:548534714
3404 3404 c, t dbSNP:759017724
3456 3456 -, tt dbSNP:753457266
3458 3458 c, t dbSNP:570079042
3464 3464 -, aaag dbSNP:757650001
3473 3473 a, g dbSNP:374079963
3527 3527 c, t dbSNP:537537158
3533 3533 -, gaaa dbSNP:779981413
3562 3562 a, c dbSNP:764774960
3577 3577 c, t dbSNP:549044068
3588 3588 a, g dbSNP:549750031
3594 3594 c, t dbSNP:368261876
3595 3595 a, g dbSNP:567936067
3672 3672 c, g dbSNP:188775926
3673 3673 -, a dbSNP:774498082
3677 3677 a, g dbSNP:73944983
3695 3695 -, a dbSNP:56376358
3702 3702 -, a dbSNP:397738242
3753 3753 a, t dbSNP:571976107
3754 3754 g, t dbSNP:535893693
3765 3765 g, t dbSNP:554529908
3791 3791 a, t dbSNP:146479913
3819 3819 c, t dbSNP:192873644
3830 3830 a, g dbSNP:184402865
3841 3841 g, t dbSNP:558636384
3860 3860 -, gcgg dbSNP:554405673
3905 3905 c, t dbSNP:10427165
3920 3920 a, g dbSNP:187906743
3948 3948 a, g dbSNP:377432639
3959 3959 a, g dbSNP:370171384
3975 3975 a, g dbSNP:751910388
3987 3987 a, g dbSNP:530396526
4041 4041 g, t dbSNP:559147905
4091 4091 -, ctctc dbSNP:764865358
4132 4132 c, t dbSNP:781314890
4140 4140 a, g dbSNP:746068232
4195 4195 c, t dbSNP:541891446
4300 4300 c, g dbSNP:563689881
4367 4367 a, g dbSNP:530954847
4399 4399 c, t dbSNP:772999840
4441 4441 a, c dbSNP:568979221
4500 4500 c, g dbSNP:552255787

Target ORF information:

RefSeq Version NM_006236
Organism Homo sapiens (human)
Definition Homo sapiens POU class 3 homeobox 3 (POU3F3), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_006236

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGCCACGG CGGCTTCTAA CCCCTACCTG CCGGGGAACA GCCTGCTCGC GGCCGGCTCT 
ATTGTGCACT CGGACGCGGC AGGGGCTGGC GGCGGCGGGG GTGGCGGCGG CGGCGGCGGC
GGGGGCGGCG CAGGGGGCGG GGGCGGCGGC ATGCAGCCGG GCAGCGCCGC CGTGACCTCG
GGCGCCTACC GGGGGGACCC GTCCTCTGTC AAGATGGTCC AGAGCGACTT CATGCAGGGG
GCCATGGCCG CCAGCAACGG CGGCCATATG CTGAGCCACG CGCACCAGTG GGTCACAGCC
CTGCCCCACG CCGCCGCCGC CGCCGCCGCT GCCGCCGCCG CCGCCGTGGA GGCGAGCTCG
CCGTGGTCGG GCAGCGCCGT GGGCATGGCT GGCAGCCCCC AGCAGCCACC GCAGCCGCCG
CCGCCACCGC CGCAGGGCCC CGACGTGAAG GGCGGCGCCG GGCGCGACGA CCTGCACGCG
GGCACAGCGC TGCACCACCG CGGGCCGCCG CACCTCGGAC CCCCGCCGCC GCCCCCACAC
CAGGGCCACC CTGGGGGCTG GGGGGCGGCC GCCGCTGCCG CAGCCGCAGC CGCCGCCGCC
GCCGCCGCCG CGCACCTCCC GTCCATGGCC GGGGGCCAGC AGCCGCCGCC GCAGAGTCTG
CTCTACTCGC AGCCCGGAGG CTTCACGGTG AACGGCATGC TGAGCGCGCC ACCGGGGCCC
GGCGGCGGCG GCGGCGGCGC GGGCGGTGGA GCCCAGAGCT TGGTGCACCC GGGGCTGGTG
CGCGGGGACA CGCCAGAGCT GGCCGAGCAC CACCACCACC ACCACCACCA CGCGCATCCT
CACCCGCCGC ACCCGCACCA CGCGCAGGGA CCCCCGCACC ACGGCGGCGG CGGCGGCGGC
GCGGGGCCTG GACTCAACAG CCACGACCCG CACTCGGACG AGGACACGCC GACGTCGGAC
GACCTGGAGC AGTTCGCCAA GCAGTTCAAG CAGCGGCGCA TCAAGCTGGG CTTCACGCAG
GCCGACGTGG GGTTGGCGCT GGGCACACTC TACGGCAACG TGTTCTCGCA GACCACCATC
TGCCGCTTCG AGGCCCTGCA GCTGAGCTTC AAGAACATGT GCAAGCTCAA GCCGCTGCTG
AACAAGTGGC TGGAGGAGGC GGACTCAAGC ACCGGCAGCC CCACAAGCAT CGACAAGATC
GCGGCGCAGG GCCGCAAGCG CAAGAAGCGG ACCTCTATCG AGGTGAGCGT CAAGGGCGCG
CTGGAGAGCC ACTTCCTCAA GTGCCCCAAG CCCTCCGCGC AGGAGATCAC CAACCTGGCC
GACAGCCTGC AGCTCGAGAA GGAGGTGGTG CGGGTCTGGT TCTGCAATCG GCGCCAAAAG
GAGAAGCGCA TGACGCCGCC CGGGATCCAA CAGCAGACGC CCGACGACGT CTACTCGCAG
GTGGGCACCG TGAGCGCCGA CACGCCGCCG CCTCACCACG GGCTGCAGAC GAGCGTTCAG
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.