The following MAGEL2 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGEL2 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 3750bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||MAGE-like protein 2
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AC124309.7.
This sequence is a reference standard in the RefSeqGene project.
On Sep 12, 2009 this sequence version replaced gi:148746205.
Summary: Prader-Willi syndrome (PWS) is caused by the loss of
expression of imprinted genes in chromosome 15q11-q13 region.
Affected individuals exhibit neonatal hypotonia, developmental
delay, and childhood-onset obesity. Necdin (NDN), a gene involved
in the terminal differentiation of neurons, localizes to this
region of the genome and has been implicated as one of the genes
responsible for the etiology of PWS. This gene is structurally
similar to NDN, is also localized to the PWS chromosomal region,
and is paternally imprinted, suggesting a possible role for it in
PWS. [provided by RefSeq, Oct 2010].
Sequence Note: The RefSeq transcript and protein were derived from
genomic sequence to make the sequence consistent with the reference
genome assembly. The genomic coordinates used for the transcript
record were based on alignments.
imprinted gene :: PMID: 10556298, 10915770
COMPLETENESS: complete on the 3' end.