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POU3F4 cDNA ORF clone, Homo sapiens (human)

Gene Symbol POU3F4
Entrez Gene ID 5456
Full Name POU class 3 homeobox 4
Synonyms BRAIN-4, BRN-4, BRN4, DFN3, DFNX2, OCT-9, OTF-9, OTF9
General protein information
Preferred Names
POU domain, class 3, transcription factor 4
Names
POU domain, class 3, transcription factor 4
octamer-binding transcription factor 9
brain-specific homeobox/POU domain protein 4
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xq21.1

Summary This gene encodes a member of the POU-III class of neural transcription factors. This family member plays a role in inner ear development. The protein is thought to be involved in the mediation of epigenetic signals which induce striatal neuron-precursor differentiation. Mutations in this gene are associated with X chromosome-linked nonsyndromic mixed deafness. [provided by RefSeq, Dec 2012]. lac of sum
Disorder MIM:

300039

Disorder Html: Deafness, X-linked 2, 304400 (3)





The following POU3F4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the POU3F4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu20520 NM_000307 Homo sapiens POU class 3 homeobox 4 (POU3F4), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$209.30
$299.00

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**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu20520
Accession Version NM_000307.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1086bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 04-MAY-2014
Organism Homo sapiens (human)
Product POU domain, class 3, transcription factor 4
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK314967.1, Z82170.3 and X82324.1. This sequence is a reference standard in the RefSeqGene project. On Dec 26, 2012 this sequence version replaced gi:194440735. Summary: This gene encodes a member of the POU-III class of neural transcription factors. This family member plays a role in inner ear development. The protein is thought to be involved in the mediation of epigenetic signals which induce striatal neuron-precursor differentiation. Mutations in this gene are associated with X chromosome-linked nonsyndromic mixed deafness. [provided by RefSeq, Dec 2012]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGCCACAG CTGCCTCGAA TCCCTACAGC ATTCTCAGTT CCACCTCCCT AGTCCATGCG 
GACTCTGCGG GCATGCAGCA GGGGAGTCCT TTCCGCAACC CTCAGAAACT TCTCCAAAGT
GATTACTTGC AGGGAGTTCC CAGCAATGGG CATCCCCTCG GGCATCACTG GGTGACCAGT
CTGAGCGACG GGGGCCCATG GTCCTCCACA CTGGCCACCA GCCCCCTGGA CCAGCAGGAC
GTGAAGCCCG GGCGCGAAGA CCTGCAACTG GGTGCGATCA TCCATCACCG CTCGCCACAC
GTAGCCCACC ACTCACCGCA CACTAACCAC CCCAACGCCT GGGGGGCCAG CCCGGCACCG
AACCCGTCTA TCACGTCAAG CGGCCAACCC CTCAACGTGT ACTCGCAGCC TGGCTTCACC
GTGAGCGGCA TGCTGGAACA CGGGGGACTC ACCCCACCTC CAGCTGCCGC CTCTGCACAG
AGCCTGCACC CGGTGCTCCG AGAGCCCCCG GATCACGGCG AACTGGGCTC GCACCATTGC
CAGGATCACT CCGACGAGGA GACGCCAACC TCTGATGAGT TGGAACAGTT CGCCAAACAA
TTCAAACAAA GAAGAATCAA GTTGGGCTTC ACGCAGGCCG ACGTGGGGTT GGCGCTGGGC
ACACTGTATG GTAACGTGTT CTCGCAGACC ACCATCTGCA GGTTCGAGGC CTTGCAGCTG
AGCTTCAAAA ATATGTGCAA GCTGAAGCCC CTGCTGAACA AGTGGCTGGA GGAGGCGGAT
TCGTCCACAG GGAGCCCGAC CAGCATTGAC AAGATCGCTG CACAGGGCCG CAAGCGCAAG
AAGCGGACCT CCATCGAGGT GAGTGTCAAG GGCGTACTGG AGACGCATTT CCTCAAGTGT
CCCAAGCCTG CCGCGCAGGA GATCTCCTCG CTGGCAGACA GCCTCCAGTT GGAGAAGGAA
GTGGTGCGTG TCTGGTTCTG TAATCGAAGA CAAAAAGAGA AAAGAATGAC TCCGCCAGGG
GATCAGCAGC CGCATGAGGT TTATTCGCAC ACCGTGAAAA CAGACACATC TTGCCATGAT
CTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_000298.3
CDS65..1150
Misc Feature(1)14..16(+)
Misc Feature(2)620..844(+)
Misc Feature(3)899..1072(+)
Misc Feature(4)899..1069(+)
Misc Feature(5)905..1057(+)
Exon (1)1..1507
Gene:POU3F4
Gene Synonym:
Translation
Position Chain Variation Link
19 19 c, t dbSNP:758805534
33 33 a, c dbSNP:374967521
38 38 a, g dbSNP:762743111
46 46 c, t dbSNP:764152522
51 51 a, g dbSNP:751307224
54 54 c, t dbSNP:761636905
79 79 a, c dbSNP:767707234
82 82 c, g dbSNP:750598848
88 88 c, t dbSNP:756362293
90 90 a, c dbSNP:779934284
112 112 c, t dbSNP:753962958
123 123 a, c dbSNP:755424605
132 132 c, t dbSNP:779536644
135 135 c, g dbSNP:748488461
143 143 c, g dbSNP:772613926
148 148 a, g dbSNP:375349043
154 154 c, t dbSNP:200127998
174 174 c, t dbSNP:745476784
178 178 c, t dbSNP:769490882
181 181 a, g dbSNP:774850800
190 190 c, t dbSNP:762593341
199 199 a, g dbSNP:768447190
203 203 c, t dbSNP:144417952
213 213 a, g dbSNP:761765614
219 219 a, c dbSNP:767261687
226 226 a, g dbSNP:369124905
227 227 a, c dbSNP:760825524
230 230 c, t dbSNP:766679721
231 231 a, c dbSNP:753854662
232 232 a, c dbSNP:372901057
239 239 a, c dbSNP:766488009
240 240 a, c dbSNP:779264827
255 255 a, g dbSNP:753206337
256 256 a, g dbSNP:376048374
262 262 a, g dbSNP:759003524
279 279 c, t dbSNP:778214819
284 284 a, t dbSNP:780655471
285 285 a, g dbSNP:776921688
307 307 a, g dbSNP:769328148
313 313 a, c dbSNP:370722742
344 344 a, c dbSNP:748726844
353 353 c, g dbSNP:768166630
357 357 c, t dbSNP:773886219
365 365 a, g dbSNP:375260287
369 369 c, g dbSNP:772013350
375 375 a, t dbSNP:772975740
405 405 a, g dbSNP:111033343
417 417 a, c dbSNP:760582733
418 418 c, g dbSNP:766475054
421 421 a, g dbSNP:759663098
423 423 a, c dbSNP:765593474
429 429 c, t dbSNP:759698748
436 436 c, t dbSNP:765320605
438 438 a, c dbSNP:752828020
446 446 a, g dbSNP:571115452
448 448 -, ccaacc dbSNP:777874504
451 451 a, g dbSNP:747552234
454 454 c, t dbSNP:758915528
460 460 c, t dbSNP:764765426
468 468 c, g dbSNP:751943327
469 469 g, t dbSNP:757689948
482 482 a, c dbSNP:186010225
484 484 a, c dbSNP:748934483
494 494 a, c dbSNP:754593721
496 496 g, t dbSNP:148408866
497 497 a, c dbSNP:778339838
503 503 c, t dbSNP:747711944
505 505 c, t dbSNP:771990622
506 506 c, g dbSNP:773169987
510 510 a, g dbSNP:746754567
519 519 a, c dbSNP:770710063
526 526 a, g dbSNP:776321460
527 527 c, g dbSNP:762824898
532 532 c, t dbSNP:377423111
541 541 a, c dbSNP:763738912
543 543 a, g dbSNP:765569063
547 547 a, c dbSNP:727503376
554 554 c, t dbSNP:763166620
559 559 c, g dbSNP:56143048
563 563 c, t dbSNP:111033345
564 564 a, g dbSNP:752058465
568 568 a, g dbSNP:757738569
570 570 c, t dbSNP:200696740
571 571 c, g dbSNP:750770913
578 578 c, g dbSNP:754649841
579 579 a, g dbSNP:777439213
580 580 c, t dbSNP:778599627
586 586 a, g dbSNP:748935939
594 594 c, t dbSNP:770657036
600 600 a, t dbSNP:751518933
649 649 a, g dbSNP:202020213
652 652 c, g dbSNP:770776910
668 668 a, t dbSNP:104894920
691 691 a, c dbSNP:780983067
697 697 g, t dbSNP:368307448
715 715 -, g dbSNP:267606975
719 719 c, t dbSNP:781092151
727 727 a, g dbSNP:770109931
759 759 c, t dbSNP:397516335
772 772 agg, ggc dbSNP:386826000
772 772 -, a dbSNP:111919890
772 772 a, g dbSNP:5921978
774 774 c, g dbSNP:5921979
775 775 -, c dbSNP:113043342
791 791 a, g dbSNP:768817520
811 811 a, g dbSNP:774302063
817 817 a, g dbSNP:779713849
826 826 a, g dbSNP:767970736
834 834 a, g dbSNP:750792732
862 862 a, c, g dbSNP:186990152
873 873 a, t dbSNP:752294354
874 874 c, t dbSNP:371128139
881 881 a, g dbSNP:777196693
884 884 a, g dbSNP:1042659
892 892 c, t dbSNP:751045189
901 901 a, c dbSNP:757204998
913 913 c, t dbSNP:781033656
917 917 -, at dbSNP:397516336
925 925 a, g dbSNP:374197546
926 926 -, agtg dbSNP:730882189
930 930 c, t dbSNP:191066633
934 934 a, g dbSNP:769666063
941 941 c, t dbSNP:780027419
948 948 a, c dbSNP:749458124
949 949 c, g dbSNP:367805648
952 952 c, t dbSNP:774480747
955 955 c, t dbSNP:761868906
959 959 -, a dbSNP:267606974
964 964 c, t dbSNP:772596392
991 991 -, ctc dbSNP:111033340
999 999 c, t dbSNP:387906502
1009 1009 c, g dbSNP:772504142
1013 1013 c, t dbSNP:761189442
1014 1014 -, t dbSNP:398122516
1014 1014 g, t dbSNP:104894921
1028 1028 a, g dbSNP:111033291
1031 1031 c, g, t dbSNP:104894924
1032 1032 a, g dbSNP:727505246
1035 1035 c, t dbSNP:775336891
1054 1054 a, t dbSNP:104894923
1064 1064 a, g dbSNP:104894922
1073 1073 a, t dbSNP:766686938
1078 1078 g, t dbSNP:140485350
1082 1082 g, t dbSNP:762532750
1085 1085 a, g dbSNP:763712381
1096 1096 a, g, t dbSNP:41312552
1109 1109 c, t dbSNP:756767918
1118 1118 a, g, t dbSNP:182912945
1123 1123 a, g dbSNP:750348258
1124 1124 -, a dbSNP:398122517
1125 1125 c, t dbSNP:144463918
1150 1150 -, actg dbSNP:727503377
1160 1160 g, t dbSNP:756127565
1166 1166 -, a dbSNP:745894574
1172 1172 c, g dbSNP:201213510
1173 1173 a, c, t dbSNP:375216358
1177 1177 c, g dbSNP:760616807
1184 1184 a, g dbSNP:748233159
1193 1193 c, g dbSNP:771993476
1196 1196 a, g dbSNP:773370268
1251 1251 c, t dbSNP:771626373
1255 1255 c, t dbSNP:777244703
1291 1291 c, t dbSNP:368408951
1303 1303 c, t dbSNP:769942921
1342 1342 c, t dbSNP:775863791
1375 1375 -, ccctt dbSNP:763018226
1410 1410 c, g dbSNP:147101869
1473 1473 g, t dbSNP:751368124

Target ORF information:

RefSeq Version NM_000307
Organism Homo sapiens (human)
Definition Homo sapiens POU class 3 homeobox 4 (POU3F4), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000307

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGGCCACAG CTGCCTCGAA TCCCTACAGC ATTCTCAGTT CCACCTCCCT AGTCCATGCG 
GACTCTGCGG GCATGCAGCA GGGGAGTCCT TTCCGCAACC CTCAGAAACT TCTCCAAAGT
GATTACTTGC AGGGAGTTCC CAGCAATGGG CATCCCCTCG GGCATCACTG GGTGACCAGT
CTGAGCGACG GGGGCCCATG GTCCTCCACA CTGGCCACCA GCCCCCTGGA CCAGCAGGAC
GTGAAGCCCG GGCGCGAAGA CCTGCAACTG GGTGCGATCA TCCATCACCG CTCGCCACAC
GTAGCCCACC ACTCACCGCA CACTAACCAC CCCAACGCCT GGGGGGCCAG CCCGGCACCG
AACCCGTCTA TCACGTCAAG CGGCCAACCC CTCAACGTGT ACTCGCAGCC TGGCTTCACC
GTGAGCGGCA TGCTGGAACA CGGGGGACTC ACCCCACCTC CAGCTGCCGC CTCTGCACAG
AGCCTGCACC CGGTGCTCCG AGAGCCCCCG GATCACGGCG AACTGGGCTC GCACCATTGC
CAGGATCACT CCGACGAGGA GACGCCAACC TCTGATGAGT TGGAACAGTT CGCCAAACAA
TTCAAACAAA GAAGAATCAA GTTGGGCTTC ACGCAGGCCG ACGTGGGGTT GGCGCTGGGC
ACACTGTATG GTAACGTGTT CTCGCAGACC ACCATCTGCA GGTTCGAGGC CTTGCAGCTG
AGCTTCAAAA ATATGTGCAA GCTGAAGCCC CTGCTGAACA AGTGGCTGGA GGAGGCGGAT
TCGTCCACAG GGAGCCCGAC CAGCATTGAC AAGATCGCTG CACAGGGCCG CAAGCGCAAG
AAGCGGACCT CCATCGAGGT GAGTGTCAAG GGCGTACTGG AGACGCATTT CCTCAAGTGT
CCCAAGCCTG CCGCGCAGGA GATCTCCTCG CTGGCAGACA GCCTCCAGTT GGAGAAGGAA
GTGGTGCGTG TCTGGTTCTG TAATCGAAGA CAAAAAGAGA AAAGAATGAC TCCGCCAGGG
GATCAGCAGC CGCATGAGGT TTATTCGCAC ACCGTGAAAA CAGACACATC TTGCCATGAT
CTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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