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POU5F1B POU class 5 homeobox 1B [Homo sapiens (human)]

Gene Symbol POU5F1B
Entrez Gene ID 5462
Full Name POU class 5 homeobox 1B
Synonyms OCT4-PG1, OCT4PG1, OTF3C, OTF3P1, POU5F1P1, POU5F1P4, POU5FLC20, POU5FLC8
General protein information
Preferred Names
putative POU domain, class 5, transcription factor 1B
Names
putative POU domain, class 5, transcription factor 1B
POU 5 domain protein
POU class 5 homeobox 1 pseudogene 1
POU domain transcription factor Oct-4
octamer binding protein 3_like sequence
POU domain transcription factor OCT4-pg1
POU domain, class 5, transcription factor 1 pseudogene 1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

8

8q24.21

Summary This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development. [provided by RefSeq, Apr 2009]. lac of sum
Disorder MIM:

615739

Disorder Html:
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OHu26333 NM_001159542 Homo sapiens POU class 5 homeobox 1B (POU5F1B), mRNA. pcDNA3.1-C-(k)DYK In stock 5-7 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OHu26333D
Sequence Information ORF Nucleotide Sequence (Length: 1080bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 25-MAY-2014
Organism Homo sapiens (human)
Product putative POU domain, class 5, transcription factor 1B
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DQ486513.1. Summary: This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development. [provided by RefSeq, Apr 2009]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: DQ486513.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCGGGAC ACCTGGCTTC GGATTTCGCC TTCTCGCCCC CTCCAGGCGG TGGGGGTGAT 
GGGCCATGGG GGGCGGAGCC GGGCTGGGTT GATCCTCTGA CCTGGCTAAG CTTCCAAGGC
CCTCCTGGAG GGCCAGGAAT CGGGCCGGGG GTTGGGCCAG GCTCTGAGGT GTGGGGGATT
CCCCCTTGCC CCCCGCCGTA TGAGTTATGT GGGGGGATGG CGTACTGTGG GCCTCAGGTT
GGAGTGGGGC TAGTGCCCCA AGGCGGCTTG GAGACCTCTC AGCCTGAGAG CGAAGCAGGA
GTCGGGGTGG AGAGCAACTC CAATGGGGCC TCCCCGGAAC CCTGCACCGT CCCCCCTGGT
GCCGTGAAGC TGGAGAAGGA GAAGCTAGAG CAAAACCCGG AGAAGTCCCA GGACATCAAA
GCTCTGCAGA AAGAACTCGA GCAATTTGCC AAGCTCCTGA AGCAGAAGAG GATCACCCTG
GGATATACAC AGGCCGATGT GGGGCTCATC CTGGGGGTTC TATTTGGGAA GGTGTTCAGC
CAAAAGACCA TCTGCCGCTT TGAGGCTCTG CAGCTTAGCT TCAAGAACAT GTGTAAGCTG
CGGCCCTTGC TGCAGAAGTG GGTGGAGGAA GCTGACAACA ATGAAAATCT TCAGGAGATA
TGCAAAGCAG AAACCCTCAT GCAGGCCCGA AAGAGAAAGC GAACCAGTAT CGAGAACCGA
GTGAGAGGCA ACCTGGAGAA TTTGTTCCTG CAGTGCCCGA AACCCACACT GCAGATCAGC
CACATCGCCC AGCAGCTTGG GCTCGAGAAG GATGTGGTCC GAGTGTGGTT CTGTAACCGG
CGCCAGAAGG GCAAGCGATC AAGCAGCGAC TATGCACAAC GAGAGGATTT TGAGGCTGCT
GGGTCTCCTT TCTCAGGGGG ACCAGTGTCC TTTCCTCCGG CCCCAGGGCC CCATTTTGGT
ACCCCAGGCT ATGGGAGCCC TCACTTCACT GCACTGTACT CCTCAGTCCC TTTCCCTGAG
GGGGAAGTCT TTCCCCCAGT CTCCGTCATC ACTCTGGGCT CTCCCATGCA TTCAAACTGA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_001153014.1
CDS256..1335
Misc Feature(1)208..210(+)
Misc Feature(2)667..891(+)
Misc Feature(3)946..1119(+)
Misc Feature(4)946..1113(+)
Misc Feature(5)952..1101(+)
Exon (1)1..1599
Gene:POU5F1B
Gene Synonym:
Translation
Position Chain Variation Link
21 21 a, t dbSNP:3999777
30 30 a, g dbSNP:575620851
32 32 a, c dbSNP:185974252
41 41 -, ata dbSNP:112002137
46 46 -, aat dbSNP:374993968
66 66 c, t dbSNP:557827884
116 116 c, g dbSNP:778771426
166 166 c, t dbSNP:190348884
205 205 a, g dbSNP:4871789
207 207 a, g dbSNP:759320436
208 208 c, t dbSNP:765089745
212 212 g, t dbSNP:752846168
232 232 c, g, t dbSNP:75427380
233 233 a, c, g dbSNP:751686418
239 239 g, t dbSNP:529087148
243 243 a, g dbSNP:746230296
248 248 c, t dbSNP:756376197
260 260 c, g, t dbSNP:542388560
274 274 g, t dbSNP:576539115
285 285 c, t dbSNP:771875761
291 291 a, g dbSNP:772828845
294 294 c, g dbSNP:746560962
297 297 a, t dbSNP:770900474
303 303 a, c dbSNP:776369676
303 303 c, t dbSNP:1061391
304 304 a, g, t dbSNP:562626736
309 309 a, g dbSNP:1061393
310 310 g, t dbSNP:764898370
319 319 c, t dbSNP:775283624
324 324 a, g dbSNP:531267041
325 325 c, g, t dbSNP:551358165
328 328 a, g, t dbSNP:751627167
334 334 c, t dbSNP:767638780
336 336 a, g dbSNP:750836510
353 353 g, t dbSNP:1061394
354 354 g, t dbSNP:756666124
363 363 a, c dbSNP:780524404
366 366 c, t dbSNP:754291935
370 370 c, t dbSNP:758097906
374 374 a, c, g dbSNP:777622917
375 375 a, c, t dbSNP:376562387
378 378 a, t dbSNP:780780793
379 379 -, c dbSNP:778622812
384 384 a, g dbSNP:745755611
390 390 a, g dbSNP:769765063
396 396 c, t dbSNP:775246122
397 397 g, t dbSNP:76449652
401 401 c, t dbSNP:768862753
402 402 a, g dbSNP:533483816
406 406 a, g dbSNP:762108790
410 410 c, g dbSNP:767445127
415 415 g, t dbSNP:750546034
417 417 c, t dbSNP:761053358
418 418 g, t dbSNP:369395842
426 426 a, g dbSNP:754238636
429 429 a, g dbSNP:755456031
430 430 c, g dbSNP:779438015
432 432 g, t dbSNP:751127201
433 433 a, c dbSNP:566751463
436 436 -, c dbSNP:747688158
441 441 a, t dbSNP:3211306
444 444 -, c dbSNP:771865314
455 455 a, g dbSNP:780539306
459 459 a, g dbSNP:745433783
462 462 a, c dbSNP:1061395
462 462 a, c dbSNP:769707993
463 463 c, t dbSNP:780034679
465 465 -, g dbSNP:559727185
466 466 a, c, g, t dbSNP:535674373
466 466 -, g dbSNP:746828492
467 467 c, g dbSNP:761899644
471 471 a, g dbSNP:772377045
476 476 c, t dbSNP:773140691
477 477 a, g dbSNP:760863803
481 481 c, t dbSNP:766985841
484 484 -, g dbSNP:780624994
489 489 c, t dbSNP:1061396
489 489 g, t dbSNP:754326284
494 494 c, t dbSNP:760145963
500 500 c, t dbSNP:765660142
501 501 a, g dbSNP:753148261
502 502 a, c, g dbSNP:756839675
506 506 c, t dbSNP:749898240
508 508 c, g dbSNP:755556323
511 511 a, c dbSNP:779553954
514 514 c, t dbSNP:749175077
519 519 c, t dbSNP:754939505
520 520 a, g dbSNP:778540580
524 524 c, t dbSNP:748022749
530 530 c, t dbSNP:772168979
532 532 g, t dbSNP:773546462
537 537 c, g dbSNP:555645826
547 547 a, g dbSNP:569344346
555 555 a, t dbSNP:77810828
558 558 a, c dbSNP:760092476
559 559 a, g dbSNP:552351247
560 560 a, g dbSNP:558179946
561 561 g, t dbSNP:200266503
564 564 a, g dbSNP:763443282
566 566 a, g dbSNP:764371674
567 567 a, g dbSNP:578063220
573 573 c, t dbSNP:755785393
576 576 c, t dbSNP:765835039
577 577 a, g dbSNP:753384380
578 578 a, g dbSNP:754885540
579 579 c, t dbSNP:778964462
583 583 a, c, g dbSNP:747888292
587 587 c, t dbSNP:777438148
591 591 a, g dbSNP:747198568
596 596 c, g dbSNP:771322061
599 599 a, g dbSNP:776833446
600 600 c, t dbSNP:746005783
601 601 a, g dbSNP:770200466
603 603 a, c, t dbSNP:775999702
604 604 a, g dbSNP:190778660
606 606 a, c dbSNP:774729169
606 606 -, c dbSNP:763078225
607 607 c, t dbSNP:760289677
609 609 a, c dbSNP:766068588
610 610 a, c, g dbSNP:182632506
612 612 -, t dbSNP:764149088
618 618 a, c dbSNP:764655739
619 619 a, g dbSNP:752618852
621 621 c, g dbSNP:758286343
622 622 a, g dbSNP:554089073
626 626 c, t dbSNP:751452457
628 628 a, g dbSNP:757541776
633 633 g, t dbSNP:746846728
640 640 a, c dbSNP:781630176
641 641 c, t dbSNP:573956416
654 654 a, g dbSNP:769855568
661 661 a, c, t dbSNP:780020292
676 676 g, t dbSNP:769082871
704 704 c, g dbSNP:774674067
706 706 a, g dbSNP:762221989
714 714 a, g dbSNP:770563864
717 717 a, g dbSNP:776196455
718 718 c, g dbSNP:759119790
725 725 g, t dbSNP:188813106
729 729 a, c dbSNP:767770484
733 733 c, t dbSNP:752192997
736 736 a, g dbSNP:140000439
740 740 a, c dbSNP:764186958
744 744 a, g dbSNP:751399282
745 745 a, c dbSNP:757047532
748 748 a, c, g dbSNP:576131592
762 762 c, t dbSNP:756322889
772 772 c, g dbSNP:780149602
774 774 c, t dbSNP:749375956
782 782 a, g dbSNP:6998061
787 787 g, t dbSNP:564569832
800 800 a, c dbSNP:13273814
805 805 a, g dbSNP:772362682
811 811 c, t dbSNP:773585425
813 813 c, t dbSNP:769368694
820 820 a, g dbSNP:769385130
825 825 a, g dbSNP:779799571
839 839 a, g dbSNP:775054724
841 841 a, g dbSNP:762441006
845 845 c, t dbSNP:763703745
850 850 a, g dbSNP:774375118
852 852 a, g dbSNP:761865135
857 857 a, c, g dbSNP:767382393
863 863 c, t dbSNP:756336940
864 864 c, g dbSNP:780723367
865 865 c, t dbSNP:192151034
873 873 a, g dbSNP:753946832
884 884 a, c dbSNP:377535415
885 885 a, g dbSNP:754980784
891 891 c, g dbSNP:778975553
895 895 a, g dbSNP:13274084
896 896 a, g dbSNP:529522221
903 903 a, t dbSNP:778092645
908 908 a, g dbSNP:747394472
918 918 c, g, t dbSNP:769484945
919 919 a, g dbSNP:769463125
922 922 a, g dbSNP:748985437
923 923 a, c, t dbSNP:768235193
929 929 c, t dbSNP:761812173
930 930 a, c dbSNP:749116626
934 934 a, g dbSNP:770937336
939 939 a, g dbSNP:6998254
944 944 -, a dbSNP:774496784
964 964 a, g dbSNP:760100990
966 966 c, g dbSNP:753945426
967 967 c, g dbSNP:7002225
969 969 c, g dbSNP:765256433
973 973 c, g, t dbSNP:538376803
974 974 a, c, g dbSNP:551571407
983 983 a, g dbSNP:757507123
989 989 c, t dbSNP:781638445
990 990 a, g dbSNP:748851874
1011 1011 a, c dbSNP:571698634
1018 1018 c, g, t dbSNP:773976279
1034 1034 c, g dbSNP:772129206
1046 1046 a, c dbSNP:767622124
1047 1047 a, g dbSNP:772954529
1055 1055 a, g dbSNP:182961302
1064 1064 a, c dbSNP:554176727
1073 1073 c, t dbSNP:761530890
1075 1075 c, t dbSNP:776516653
1076 1076 a, g dbSNP:759719679
1078 1078 c, g dbSNP:765504314
1080 1080 a, g dbSNP:752774436
1084 1084 g, t dbSNP:762957047
1092 1092 c, t dbSNP:764250580
1094 1094 c, g dbSNP:751963914
1096 1096 a, c, t dbSNP:573985615
1098 1098 c, g dbSNP:533435736
1122 1122 c, t dbSNP:28409416
1123 1123 c, g dbSNP:750867584
1124 1124 a, g dbSNP:754663669
1132 1132 a, c dbSNP:778774788
1135 1135 c, t dbSNP:747805182
1137 1137 a, g dbSNP:771424910
1151 1151 c, t dbSNP:777361565
1152 1152 c, t dbSNP:746879083
1162 1162 c, t dbSNP:770937166
1167 1167 c, t dbSNP:776264328
1170 1170 -, ag, g dbSNP:533552619
1172 1172 a, g dbSNP:759396734
1174 1174 g, t dbSNP:536151237
1191 1191 g, t dbSNP:775635108
1193 1193 c, t dbSNP:556361752
1194 1194 a, g dbSNP:374138216
1198 1198 a, c dbSNP:751703386
1201 1201 a, g dbSNP:762206111
1202 1202 c, g dbSNP:768127363
1206 1206 c, g dbSNP:750810557
1213 1213 c, g dbSNP:756479586
1214 1214 a, g dbSNP:780579414
1217 1217 c, g dbSNP:371019833
1220 1220 c, t dbSNP:758096671
1242 1242 c, t dbSNP:777113684
1254 1254 -, ctc dbSNP:750747373
1254 1254 a, c dbSNP:746575607
1258 1258 c, t dbSNP:148676795
1270 1270 c, g dbSNP:142141895
1272 1272 c, t dbSNP:745822635
1273 1273 g, t dbSNP:769533326
1274 1274 a, t dbSNP:564660017
1275 1275 -, g dbSNP:545756863
1279 1279 a, g dbSNP:775485125
1281 1281 a, t dbSNP:768973800
1283 1283 a, t dbSNP:774283454
1285 1285 c, t dbSNP:762017742
1288 1288 a, c dbSNP:767497872
1289 1289 c, t dbSNP:773796757
1291 1291 c, t dbSNP:761284971
1293 1293 -, a dbSNP:766888634
1296 1296 c, t dbSNP:766805368
1299 1299 c, t dbSNP:397839847
1303 1303 a, g dbSNP:571772325
1309 1309 a, c dbSNP:763861496
1311 1311 -, g dbSNP:754368664
1313 1313 g, t dbSNP:751178428
1334 1334 a, g dbSNP:756736362
1339 1339 g, t dbSNP:780707684
1340 1340 c, t dbSNP:745769186
1343 1343 a, g dbSNP:756085416
1356 1356 c, t dbSNP:779804055
1360 1360 a, g dbSNP:373454446
1361 1361 a, g dbSNP:749166599
1363 1363 a, c, g dbSNP:187298898
1364 1364 -, ag dbSNP:755512421
1364 1364 a, g dbSNP:774564179
1366 1366 a, c, g dbSNP:371237720
1372 1372 c, g dbSNP:772229313
1406 1406 c, g dbSNP:9297754
1418 1418 a, c, g, t dbSNP:78695295
1425 1425 a, g dbSNP:549402782
1457 1457 a, c dbSNP:563132584
1459 1459 a, t dbSNP:9297755
1470 1470 a, g dbSNP:78931371
1472 1472 a, t dbSNP:182512875
1514 1514 a, g dbSNP:534247326
1534 1534 c, t dbSNP:547856508
1558 1558 c, t dbSNP:188074125
1572 1572 c, t dbSNP:3179559
1580 1580 c, t dbSNP:192359771
1582 1582 -, t dbSNP:199935435
1591 1591 a, g dbSNP:556160013
1595 1595 a, g dbSNP:200889381
1596 1596 a, g dbSNP:368932899
1599 1599 a, g dbSNP:74548710

Target ORF information:

RefSeq Version NM_001159542
Organism Homo sapiens (human)
Definition Homo sapiens POU class 5 homeobox 1B (POU5F1B), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_001159542

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
ATGGCGGGAC ACCTGGCTTC GGATTTCGCC TTCTCGCCCC CTCCAGGCGG TGGGGGTGAT 
GGGCCATGGG GGGCGGAGCC GGGCTGGGTT GATCCTCTGA CCTGGCTAAG CTTCCAAGGC
CCTCCTGGAG GGCCAGGAAT CGGGCCGGGG GTTGGGCCAG GCTCTGAGGT GTGGGGGATT
CCCCCTTGCC CCCCGCCGTA TGAGTTATGT GGGGGGATGG CGTACTGTGG GCCTCAGGTT
GGAGTGGGGC TAGTGCCCCA AGGCGGCTTG GAGACCTCTC AGCCTGAGAG CGAAGCAGGA
GTCGGGGTGG AGAGCAACTC CAATGGGGCC TCCCCGGAAC CCTGCACCGT CCCCCCTGGT
GCCGTGAAGC TGGAGAAGGA GAAGCTAGAG CAAAACCCGG AGAAGTCCCA GGACATCAAA
GCTCTGCAGA AAGAACTCGA GCAATTTGCC AAGCTCCTGA AGCAGAAGAG GATCACCCTG
GGATATACAC AGGCCGATGT GGGGCTCATC CTGGGGGTTC TATTTGGGAA GGTGTTCAGC
CAAAAGACCA TCTGCCGCTT TGAGGCTCTG CAGCTTAGCT TCAAGAACAT GTGTAAGCTG
CGGCCCTTGC TGCAGAAGTG GGTGGAGGAA GCTGACAACA ATGAAAATCT TCAGGAGATA
TGCAAAGCAG AAACCCTCAT GCAGGCCCGA AAGAGAAAGC GAACCAGTAT CGAGAACCGA
GTGAGAGGCA ACCTGGAGAA TTTGTTCCTG CAGTGCCCGA AACCCACACT GCAGATCAGC
CACATCGCCC AGCAGCTTGG GCTCGAGAAG GATGTGGTCC GAGTGTGGTT CTGTAACCGG
CGCCAGAAGG GCAAGCGATC AAGCAGCGAC TATGCACAAC GAGAGGATTT TGAGGCTGCT
GGGTCTCCTT TCTCAGGGGG ACCAGTGTCC TTTCCTCCGG CCCCAGGGCC CCATTTTGGT
ACCCCAGGCT ATGGGAGCCC TCACTTCACT GCACTGTACT CCTCAGTCCC TTTCCCTGAG
GGGGAAGTCT TTCCCCCAGT CTCCGTCATC ACTCTGGGCT CTCCCATGCA TTCAAACTGA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.