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PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 [Homo sapiens (human)]

Gene Symbol PDP1
Entrez Gene ID 54704
Full Name pyruvate dehyrogenase phosphatase catalytic subunit 1
Synonyms PDH, PDP, PDPC, PPM2C
General protein information
Preferred Names
pyruvate dehyrogenase phosphatase catalytic subunit 1
Names
pyruvate dehyrogenase phosphatase catalytic subunit 1
PDP 1
PDPC 1
pyruvate dehydrogenase phosphatase catalytic subunit 1
pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase
protein phosphatase 2C, magnesium-dependent, catalytic subunit
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial
NP_001155251.1
NP_001155252.1
NP_001155253.1
NP_060914.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

8

8q22.1

Summary Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009]. lac of sum
Disorder MIM:

605993

Disorder Html: Pyruvate dehydrogenase phosphatase deficiency, 608782 (3)





The following PDP1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PDP1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu42507 XM_011517135 PREDICTED: Homo sapiens pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $439
OHu17481 XM_011517136 PREDICTED: Homo sapiens pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$307.3
$439
OHu17481 XM_011517137 PREDICTED: Homo sapiens pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$307.3
$439
OHu17459 NM_001161780 Homo sapiens pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $469
OHu17459 NM_001161779 Homo sapiens pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $469
OHu17481 NM_001161781 Homo sapiens pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$265.3
$379
OHu17481 NM_018444 Homo sapiens pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1), transcript variant 5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$307.3
$439

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu42507
Accession Version XM_011517135.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1668bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008046.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGTTTGAAC GAATCCCAGT CAGAAGTTCC AGCCTGCCAC TGTTCTCTGA TGCCATGCCA 
GCACCAACTC AACTGTTTTT TCCTCTCATC CGTAACTGTG AACTGAGCAG GATCTATGGC
ACTGCATGTT ACTGCCACCA CAAACATCTC TGTTGTTCCT CATCGTACAT TCCTCAGAGT
CGACTGAGAT ACACACCTCA TCCAGCATAT GCTACCTTTT GCAGGCCAAA GGAGAACTGG
TGGCAGTACA CCCAAGGAAG GAGATATGCT TCCACACCAC AGAAATTTTA CCTCACACCT
CCACAAGTCA ATAGCATCCT TAAAGCTAAT GAATACAGTT TCAAAGTGCC AGAATTTGAC
GGCAAAAATG TCAGTTCTAT CCTTGGATTT GACAGCAATC AGCTGCCTGC AAATGCACCC
ATTGAGGACC GGAGAAGTGC AGCAACCTGC TTGCAGACCA GAGGGATGCT TTTGGGGGTT
TTTGATGGCC ATGCAGGTTG TGCTTGTTCC CAGGCAGTCA GTGAAAGACT CTTTTATTAT
ATTGCTGTCT CTTTGTTACC CCATGAGACT TTGCTAGAGA TTGAAAATGC AGTGGAGAGC
GGCCGGGCAC TGCTACCCAT TCTCCAGTGG CACAAGCACC CCAATGATTA CTTTAGTAAG
GAGGCATCCA AATTGTACTT TAACAGCTTG AGGACTTACT GGCAAGAGCT TATAGACCTC
AACACTGGTG AGTCGACTGA TATTGATGTT AAGGAGGCTC TAATTAATGC CTTCAAGAGG
CTTGATAATG ACATCTCCTT GGAGGCGCAA GTTGGTGATC CTAATTCTTT TCTCAACTAC
CTGGTGCTTC GAGTGGCATT TTCTGGAGCC ACTGCTTGTG TGGCCCATGT GGATGGTGTT
GACCTTCATG TGGCCAATAC TGGCGATAGC AGAGCCATGC TGGGTGTGCA GGAAGAGGAC
GGCTCATGGT CAGCAGTCAC GCTGTCTAAT GACCACAATG CTCAAAATGA AAGAGAACTA
GAACGGCTGA AATTGGAACA TCCAAAGAGT GAGGCCAAGA GTGTCGTGAA ACAGGATCGG
CTGCTTGGCT TGCTGATGCC ATTTAGGGCA TTTGGAGATG TAAAGTTCAA ATGGAGCATT
GACCTTCAAA AGAGAGTGAT AGAATCTGGC CCAGACCAGT TGAATGACAA TGAATATACC
AAGTTTATTC CTCCTAATTA TCACACACCT CCTTATCTCA CTGCTGAGCC AGAGGTAACT
TACCACCGAT TAAGGCCACA GGATAAGTTT CTGGTGTTGG CTACTGATGG GTTGTGGGAG
ACTATGCATA GGCAGGATGT GGTTAGGATT GTGGGTGAGT ACCTAACTGG CATGCATCAC
CAACAGCCAA TAGCTGTTGG TGGCTACAAG GTGACTCTGG GACAGATGCA TGGCCTTTTA
ACAGAAAGGA GAACCAAAAT GTCCTCGGTA TTTGAGGATC AGAACGCAGC AACCCATCTC
ATTCGCCACG CTGTGGGCAA CAACGAGTTT GGGACTGTTG ATCATGAGCG CCTCTCTAAA
ATGCTTAGTC TTCCTGAAGA GCTTGCTCGA ATGTACAGAG ATGACATTAC AATCATTGTA
GTTCAGTTCA ATTCTCATGT TGTAGGGGCG TATCAAAACC AAGAATAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011515437.1
CDS45..1712
Misc Feature(1)423..1673(+)
Misc Feature(2)456..1646(+)
Translation
Position Chain Variation Link
6 6 g, t dbSNP:764786849
57 57 a, g dbSNP:368896704
60 60 c, t dbSNP:745378971
72 72 c, t dbSNP:76597597
74 74 c, t dbSNP:771654817
75 75 a, t dbSNP:779914919
76 76 g, t dbSNP:746656680
84 84 -, t dbSNP:748745930
86 86 c, g dbSNP:373914341
89 89 a, c dbSNP:767109728
94 94 a, g dbSNP:763177277
95 95 a, t dbSNP:771499042
99 99 a, g dbSNP:774772187
103 103 c, t dbSNP:775877089
111 111 a, g dbSNP:759621538
112 112 c, g dbSNP:376864107
114 114 c, t dbSNP:775755715
116 116 a, c dbSNP:760854097
118 118 a, t dbSNP:763841975
120 120 c, t dbSNP:753700131
122 122 c, t dbSNP:756937580
123 123 c, t dbSNP:371323550
130 130 c, t dbSNP:765234818
135 135 c, t dbSNP:750372945
136 136 a, g dbSNP:758052799
145 145 a, t dbSNP:760929995
148 148 c, t dbSNP:746711864
154 154 a, g dbSNP:754684543
160 160 a, g dbSNP:780665993
164 164 c, t dbSNP:749664764
166 166 c, g dbSNP:771139058
171 171 c, t dbSNP:774892672
172 172 a, g dbSNP:746369657
182 182 c, t dbSNP:772178775
185 185 c, t dbSNP:758947272
189 189 c, t dbSNP:201452113
190 190 a, g, t dbSNP:764383471
209 209 a, c, g, t dbSNP:761727112
222 222 a, g dbSNP:758390717
225 225 c, t dbSNP:766372826
226 226 a, g dbSNP:201081450
228 228 c, g dbSNP:754376963
229 229 c, t dbSNP:780907656
243 243 c, t dbSNP:747738989
252 252 c, t dbSNP:140713866
281 281 c, t dbSNP:779217265
293 293 c, t dbSNP:375147234
294 294 a, g dbSNP:569067471
299 299 a, c, g dbSNP:775911139
300 300 a, g dbSNP:374758737
310 310 a, g dbSNP:776979550
312 312 g, t dbSNP:761913953
313 313 c, t dbSNP:769765131
324 324 a, c dbSNP:773166625
337 337 c, t dbSNP:79439881
355 355 a, g dbSNP:762798871
359 359 c, t dbSNP:144544236
369 369 a, g dbSNP:751392690
372 372 a, g dbSNP:759139812
374 374 c, t dbSNP:766927852
375 375 g, t dbSNP:267606938
382 382 a, g dbSNP:368756677
404 404 c, t dbSNP:755698784
405 405 a, g dbSNP:777354361
423 423 a, g dbSNP:750815139
426 426 c, g dbSNP:758705968
440 440 c, g, t dbSNP:780597558
443 443 c, t dbSNP:768820696
449 449 g, t dbSNP:781113804
462 462 c, g dbSNP:748213138
465 465 a, c, g dbSNP:144604949
474 474 a, c, t dbSNP:565152013
475 475 a, g dbSNP:147845975
476 476 c, g dbSNP:759361135
495 495 c, t dbSNP:767102971
502 502 c, g dbSNP:752170333
503 503 c, t dbSNP:376531662
504 504 a, c dbSNP:201131767
516 516 c, t dbSNP:141399719
519 519 a, g dbSNP:151019488
521 521 a, g dbSNP:368265235
523 523 -, t dbSNP:768282589
581 581 c, t dbSNP:758829356
590 590 g, t dbSNP:780250994
591 591 a, g dbSNP:752161030
599 599 a, g, t dbSNP:755465648
608 608 a, t dbSNP:200661557
613 613 c, t dbSNP:750529031
633 633 a, g dbSNP:769934912
634 634 c, g, t dbSNP:778196214
635 635 a, g dbSNP:770886339
639 639 c, g dbSNP:773995220
644 644 c, t dbSNP:202034256
647 647 c, t dbSNP:771933821
648 648 c, t dbSNP:775429341
649 649 a, g dbSNP:760238687
654 654 c, t dbSNP:763591084
655 655 c, g, t dbSNP:572895007
668 668 c, t dbSNP:764899090
698 698 a, c, t dbSNP:541907484
708 708 a, g dbSNP:767925776
721 721 a, g dbSNP:753240948
739 739 c, t dbSNP:200145429
749 749 a, g dbSNP:777966209
752 752 a, g dbSNP:749570505
755 755 c, t dbSNP:374859758
767 767 c, t dbSNP:138512618
769 769 c, t dbSNP:140780685
776 776 c, g dbSNP:199977411
778 778 c, t dbSNP:771889434
779 779 a, g dbSNP:369055053
782 782 c, t dbSNP:757895185
787 787 c, g, t dbSNP:201467137
788 788 c, t dbSNP:776144330
791 791 c, t dbSNP:761277113
803 803 g, t dbSNP:764804506
804 804 c, t dbSNP:772866221
815 815 c, g dbSNP:150112501
836 836 c, t dbSNP:767917111
851 851 a, g dbSNP:138553326
874 874 g, t dbSNP:750473319
875 875 g, t dbSNP:753292297
878 878 c, t dbSNP:140224111
880 880 a, g dbSNP:145915456
883 883 a, c dbSNP:754001678
895 895 a, g dbSNP:757292942
902 902 a, g dbSNP:779015042
905 905 a, t dbSNP:746100755
914 914 c, t dbSNP:758169742
926 926 a, g dbSNP:779802119
929 929 c, t dbSNP:746758163
945 945 g, t dbSNP:768615485
953 953 c, t dbSNP:201021364
961 961 a, g dbSNP:747673653
968 968 c, t dbSNP:561440517
969 969 a, g dbSNP:772803719
976 976 a, g dbSNP:762632055
984 984 c, g dbSNP:758604713
990 990 a, g dbSNP:373016029
995 995 a, g dbSNP:776018911
996 996 c, g dbSNP:780162130
998 998 a, g dbSNP:761080494
1004 1004 c, t dbSNP:138488258
1007 1007 c, t dbSNP:146222349
1011 1011 c, t dbSNP:149633208
1017 1017 g, t dbSNP:765330955
1024 1024 c, t dbSNP:750660703
1025 1025 a, g dbSNP:758670020
1035 1035 a, g dbSNP:780213686
1042 1042 a, g dbSNP:751365113
1049 1049 a, g dbSNP:754713600
1065 1065 a, g dbSNP:370143029
1069 1069 a, g dbSNP:748108713
1077 1077 c, t dbSNP:373354872
1078 1078 g, t dbSNP:529355400
1091 1091 a, g dbSNP:200054483
1099 1099 c, g dbSNP:770737506
1100 1100 c, g dbSNP:774080309
1109 1109 c, t dbSNP:761133347
1110 1110 a, g dbSNP:769128065
1119 1119 c, g dbSNP:144339806
1122 1122 c, t dbSNP:762362258
1127 1127 c, g dbSNP:755900273
1128 1128 c, t dbSNP:534701211
1131 1131 -, g dbSNP:774046054
1166 1166 a, g dbSNP:769050733
1188 1188 c, g dbSNP:750548247
1202 1202 a, g dbSNP:762878527
1205 1205 a, g dbSNP:766605438
1217 1217 a, g dbSNP:751770350
1227 1227 a, t dbSNP:754838278
1228 1228 a, g dbSNP:780930808
1241 1241 c, t dbSNP:752624152
1251 1251 a, t dbSNP:777603105
1256 1256 c, t dbSNP:777530209
1267 1267 a, c dbSNP:748834473
1269 1269 a, t dbSNP:756767503
1274 1274 g, t dbSNP:778764676
1280 1280 c, t dbSNP:745485872
1302 1302 a, g dbSNP:769193664
1307 1307 c, t dbSNP:777075890
1311 1311 c, t dbSNP:377342640
1312 1312 a, g dbSNP:770342233
1326 1326 g, t dbSNP:369447724
1327 1327 a, g dbSNP:763153521
1331 1331 a, g dbSNP:374326474
1340 1340 a, g dbSNP:148348306
1349 1349 c, t dbSNP:774592444
1356 1356 g, t dbSNP:759729815
1365 1365 a, g dbSNP:767674134
1372 1372 a, g dbSNP:200222464
1379 1379 a, c, g dbSNP:141493326
1382 1382 c, t dbSNP:753703262
1402 1402 a, g dbSNP:756892474
1409 1409 a, t dbSNP:778545811
1414 1414 a, g dbSNP:745323862
1416 1416 a, g dbSNP:758156720
1420 1420 a, g dbSNP:779506684
1427 1427 a, c dbSNP:748562555
1439 1439 g, t dbSNP:770046269
1440 1440 a, g dbSNP:749168775
1452 1452 a, g dbSNP:773838560
1453 1453 a, g dbSNP:749767366
1454 1454 a, g dbSNP:771044295
1461 1461 c, g dbSNP:373946288
1464 1464 a, g dbSNP:759570204
1473 1473 c, g dbSNP:767783621
1478 1478 -, cctttta dbSNP:747806749
1491 1491 a, g dbSNP:775515661
1496 1496 a, g dbSNP:760576538
1498 1498 c, g dbSNP:763792118
1500 1500 a, g dbSNP:377553463
1511 1511 a, g dbSNP:757283913
1515 1515 c, t dbSNP:201132164
1521 1521 g, t dbSNP:749959908
1523 1523 a, t dbSNP:757927785
1527 1527 a, g dbSNP:779817145
1529 1529 c, t dbSNP:147477305
1530 1530 a, g dbSNP:756545344
1532 1532 a, g dbSNP:117294206
1544 1544 a, c, t dbSNP:137975172
1545 1545 a, g dbSNP:370390664
1548 1548 c, t dbSNP:745958515
1553 1553 c, t dbSNP:374262682
1559 1559 a, g dbSNP:775848242
1564 1564 a, g dbSNP:760776715
1568 1568 c, t dbSNP:768875523
1579 1579 c, t dbSNP:776599018
1593 1593 c, t dbSNP:761636189
1594 1594 a, g dbSNP:376060350
1600 1600 c, g dbSNP:750375166
1601 1601 c, t dbSNP:762593464
1618 1618 c, g dbSNP:145358369
1625 1625 a, g dbSNP:751277921
1632 1632 c, t dbSNP:202225648
1643 1643 a, g dbSNP:754605931
1656 1656 a, g dbSNP:202145000
1665 1665 c, g dbSNP:754204252
1668 1668 c, g dbSNP:147237491
1675 1675 a, g dbSNP:779452040
1677 1677 c, t dbSNP:746369671
1683 1683 g, t dbSNP:772232968
1686 1686 a, g dbSNP:780020258
1688 1688 -, g dbSNP:772846653
1691 1691 a, g dbSNP:747071043
1693 1693 c, t dbSNP:768767735
1694 1694 a, g dbSNP:535568386
1712 1712 c, g dbSNP:139199750
1713 1713 c, t dbSNP:761761105
1714 1714 c, g dbSNP:769711015
1726 1726 c, t dbSNP:773326652
1728 1728 a, c dbSNP:762781777
1732 1732 c, g dbSNP:766287359
1734 1734 a, g dbSNP:555465685
1737 1737 c, g dbSNP:41272415
1743 1743 c, t dbSNP:759016944
1748 1748 c, t dbSNP:4735258
1749 1749 a, g dbSNP:752331175
1750 1750 c, t dbSNP:757684185
1751 1751 a, g dbSNP:765555188
1758 1758 a, g, t dbSNP:750976092
1761 1761 a, c dbSNP:192535454
1763 1763 g, t dbSNP:149521176
1771 1771 a, t dbSNP:540479716
1777 1777 a, g dbSNP:144036151
1783 1783 c, t dbSNP:148691545
1794 1794 a, g dbSNP:542596810
1805 1805 a, g dbSNP:144473673
1869 1869 -, a dbSNP:760027289
1892 1892 c, t dbSNP:577643189
2003 2003 a, g dbSNP:769186837
2013 2013 a, g dbSNP:531689009
2080 2080 c, g dbSNP:551728387
2085 2085 c, t dbSNP:185126352
2105 2105 c, t dbSNP:527981638
2132 2132 c, t dbSNP:548043412
2164 2164 c, t dbSNP:566488276
2170 2170 a, t dbSNP:535475031
2203 2203 g, t dbSNP:41272417
2221 2221 a, c, g dbSNP:199846257
2278 2278 c, t dbSNP:78884124
2304 2304 a, g dbSNP:537935933
2310 2310 c, t dbSNP:557676479
2322 2322 a, g dbSNP:190420045
2333 2333 a, g dbSNP:545692596
2341 2341 a, g dbSNP:192629673
2343 2343 c, g dbSNP:911
2351 2351 a, g dbSNP:147461233
2357 2357 c, g dbSNP:762341289
2367 2367 a, g dbSNP:185015320
2378 2378 -, g dbSNP:139623857
2415 2415 a, g dbSNP:562533870
2423 2423 a, g dbSNP:554502999
2439 2439 c, t dbSNP:545440707
2519 2519 a, c dbSNP:188727327
2524 2524 a, g dbSNP:765693471
2570 2570 c, t dbSNP:750465585
2571 2571 a, g dbSNP:527854224
2586 2586 g, t dbSNP:572912702
2598 2598 c, t dbSNP:547657737
2610 2610 -, ctt dbSNP:756226872
2622 2622 a, t dbSNP:7461396
2642 2642 a, g dbSNP:180752222
2669 2669 a, g dbSNP:75265995
2714 2714 -, g dbSNP:35866235
2719 2719 a, g dbSNP:185360919
2741 2741 c, g dbSNP:762919416
2803 2803 a, c dbSNP:568829851
2812 2812 a, g dbSNP:540442395
2825 2825 c, t dbSNP:537546709
2826 2826 a, g dbSNP:551427862
2839 2839 c, t dbSNP:766520277
2915 2915 -, g dbSNP:35793146
2940 2940 a, c dbSNP:571367515
2951 2951 a, c dbSNP:751718373
2962 2962 a, g dbSNP:534020211
3036 3036 a, c, g dbSNP:774244422
3045 3045 a, g dbSNP:553548239
3053 3053 g, t dbSNP:573640783
3062 3062 c, t dbSNP:561592504
3118 3118 a, c dbSNP:753665809
3121 3121 a, g dbSNP:757140568
3131 3131 a, c dbSNP:201779185
3154 3154 a, g dbSNP:748740342
3199 3199 a, t dbSNP:189435075
3208 3208 a, t dbSNP:576359274
3223 3223 c, t dbSNP:745862328
3229 3229 a, g dbSNP:545190275
3250 3250 c, t dbSNP:771482216
3261 3261 c, t dbSNP:565409416
3263 3263 g, t dbSNP:779668197
3276 3276 a, c dbSNP:111728711
3321 3321 a, g dbSNP:186669527
3360 3360 -, t dbSNP:778564057
3360 3360 -, g dbSNP:145384326
3361 3361 g, t dbSNP:377214447
3362 3362 g, t dbSNP:192025344
3373 3373 -, t dbSNP:60316663
3376 3376 a, g dbSNP:558897089
3402 3402 a, g dbSNP:777095381
3432 3432 a, g dbSNP:566314054
3448 3448 c, g dbSNP:116788695
3474 3474 c, t dbSNP:568255963
3500 3500 -, c dbSNP:753816030
3511 3511 c, g dbSNP:535028389
3515 3515 c, g dbSNP:773560152
3517 3517 a, g dbSNP:531302765
3519 3519 a, t dbSNP:77734416
3542 3542 c, g dbSNP:571368323
3549 3549 a, g dbSNP:533642903
3558 3558 a, g dbSNP:537145163
3570 3570 a, g dbSNP:767466121
3581 3581 a, g dbSNP:553341714
3618 3618 g, t dbSNP:567078023
3634 3634 a, t dbSNP:139839619
3662 3662 c, t dbSNP:751645556
3787 3787 -, a dbSNP:368109978
3798 3798 a, g dbSNP:556007957
3807 3807 c, t dbSNP:115434133
3927 3927 g, t dbSNP:759715556
3942 3942 a, t dbSNP:767751976
3967 3967 c, t dbSNP:183503324
3969 3969 a, t dbSNP:367694582
3975 3975 c, t dbSNP:145337691
4012 4012 -, a dbSNP:539401507
4025 4025 g, t dbSNP:754099555
4048 4048 a, t dbSNP:186410170
4065 4065 g, t dbSNP:190113849
4097 4097 a, t dbSNP:557560034
4103 4103 -, c dbSNP:745781350

Target ORF information:

RefSeq Version XM_011517135
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011517135

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGTTTGAAC GAATCCCAGT CAGAAGTTCC AGCCTGCCAC TGTTCTCTGA TGCCATGCCA 
GCACCAACTC AACTGTTTTT TCCTCTCATC CGTAACTGTG AACTGAGCAG GATCTATGGC
ACTGCATGTT ACTGCCACCA CAAACATCTC TGTTGTTCCT CATCGTACAT TCCTCAGAGT
CGACTGAGAT ACACACCTCA TCCAGCATAT GCTACCTTTT GCAGGCCAAA GGAGAACTGG
TGGCAGTACA CCCAAGGAAG GAGATATGCT TCCACACCAC AGAAATTTTA CCTCACACCT
CCACAAGTCA ATAGCATCCT TAAAGCTAAT GAATACAGTT TCAAAGTGCC AGAATTTGAC
GGCAAAAATG TCAGTTCTAT CCTTGGATTT GACAGCAATC AGCTGCCTGC AAATGCACCC
ATTGAGGACC GGAGAAGTGC AGCAACCTGC TTGCAGACCA GAGGGATGCT TTTGGGGGTT
TTTGATGGCC ATGCAGGTTG TGCTTGTTCC CAGGCAGTCA GTGAAAGACT CTTTTATTAT
ATTGCTGTCT CTTTGTTACC CCATGAGACT TTGCTAGAGA TTGAAAATGC AGTGGAGAGC
GGCCGGGCAC TGCTACCCAT TCTCCAGTGG CACAAGCACC CCAATGATTA CTTTAGTAAG
GAGGCATCCA AATTGTACTT TAACAGCTTG AGGACTTACT GGCAAGAGCT TATAGACCTC
AACACTGGTG AGTCGACTGA TATTGATGTT AAGGAGGCTC TAATTAATGC CTTCAAGAGG
CTTGATAATG ACATCTCCTT GGAGGCGCAA GTTGGTGATC CTAATTCTTT TCTCAACTAC
CTGGTGCTTC GAGTGGCATT TTCTGGAGCC ACTGCTTGTG TGGCCCATGT GGATGGTGTT
GACCTTCATG TGGCCAATAC TGGCGATAGC AGAGCCATGC TGGGTGTGCA GGAAGAGGAC
GGCTCATGGT CAGCAGTCAC GCTGTCTAAT GACCACAATG CTCAAAATGA AAGAGAACTA
GAACGGCTGA AATTGGAACA TCCAAAGAGT GAGGCCAAGA GTGTCGTGAA ACAGGATCGG
CTGCTTGGCT TGCTGATGCC ATTTAGGGCA TTTGGAGATG TAAAGTTCAA ATGGAGCATT
GACCTTCAAA AGAGAGTGAT AGAATCTGGC CCAGACCAGT TGAATGACAA TGAATATACC
AAGTTTATTC CTCCTAATTA TCACACACCT CCTTATCTCA CTGCTGAGCC AGAGGTAACT
TACCACCGAT TAAGGCCACA GGATAAGTTT CTGGTGTTGG CTACTGATGG GTTGTGGGAG
ACTATGCATA GGCAGGATGT GGTTAGGATT GTGGGTGAGT ACCTAACTGG CATGCATCAC
CAACAGCCAA TAGCTGTTGG TGGCTACAAG GTGACTCTGG GACAGATGCA TGGCCTTTTA
ACAGAAAGGA GAACCAAAAT GTCCTCGGTA TTTGAGGATC AGAACGCAGC AACCCATCTC
ATTCGCCACG CTGTGGGCAA CAACGAGTTT GGGACTGTTG ATCATGAGCG CCTCTCTAAA
ATGCTTAGTC TTCCTGAAGA GCTTGCTCGA ATGTACAGAG ATGACATTAC AATCATTGTA
GTTCAGTTCA ATTCTCATGT TGTAGGGGCG TATCAAAACC AAGAATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17481
Accession Version XM_011517136.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1614bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008046.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGCCAGCAC CAACTCAACT GTTTTTTCCT CTCATCCGTA ACTGTGAACT GAGCAGGATC 
TATGGCACTG CATGTTACTG CCACCACAAA CATCTCTGTT GTTCCTCATC GTACATTCCT
CAGAGTCGAC TGAGATACAC ACCTCATCCA GCATATGCTA CCTTTTGCAG GCCAAAGGAG
AACTGGTGGC AGTACACCCA AGGAAGGAGA TATGCTTCCA CACCACAGAA ATTTTACCTC
ACACCTCCAC AAGTCAATAG CATCCTTAAA GCTAATGAAT ACAGTTTCAA AGTGCCAGAA
TTTGACGGCA AAAATGTCAG TTCTATCCTT GGATTTGACA GCAATCAGCT GCCTGCAAAT
GCACCCATTG AGGACCGGAG AAGTGCAGCA ACCTGCTTGC AGACCAGAGG GATGCTTTTG
GGGGTTTTTG ATGGCCATGC AGGTTGTGCT TGTTCCCAGG CAGTCAGTGA AAGACTCTTT
TATTATATTG CTGTCTCTTT GTTACCCCAT GAGACTTTGC TAGAGATTGA AAATGCAGTG
GAGAGCGGCC GGGCACTGCT ACCCATTCTC CAGTGGCACA AGCACCCCAA TGATTACTTT
AGTAAGGAGG CATCCAAATT GTACTTTAAC AGCTTGAGGA CTTACTGGCA AGAGCTTATA
GACCTCAACA CTGGTGAGTC GACTGATATT GATGTTAAGG AGGCTCTAAT TAATGCCTTC
AAGAGGCTTG ATAATGACAT CTCCTTGGAG GCGCAAGTTG GTGATCCTAA TTCTTTTCTC
AACTACCTGG TGCTTCGAGT GGCATTTTCT GGAGCCACTG CTTGTGTGGC CCATGTGGAT
GGTGTTGACC TTCATGTGGC CAATACTGGC GATAGCAGAG CCATGCTGGG TGTGCAGGAA
GAGGACGGCT CATGGTCAGC AGTCACGCTG TCTAATGACC ACAATGCTCA AAATGAAAGA
GAACTAGAAC GGCTGAAATT GGAACATCCA AAGAGTGAGG CCAAGAGTGT CGTGAAACAG
GATCGGCTGC TTGGCTTGCT GATGCCATTT AGGGCATTTG GAGATGTAAA GTTCAAATGG
AGCATTGACC TTCAAAAGAG AGTGATAGAA TCTGGCCCAG ACCAGTTGAA TGACAATGAA
TATACCAAGT TTATTCCTCC TAATTATCAC ACACCTCCTT ATCTCACTGC TGAGCCAGAG
GTAACTTACC ACCGATTAAG GCCACAGGAT AAGTTTCTGG TGTTGGCTAC TGATGGGTTG
TGGGAGACTA TGCATAGGCA GGATGTGGTT AGGATTGTGG GTGAGTACCT AACTGGCATG
CATCACCAAC AGCCAATAGC TGTTGGTGGC TACAAGGTGA CTCTGGGACA GATGCATGGC
CTTTTAACAG AAAGGAGAAC CAAAATGTCC TCGGTATTTG AGGATCAGAA CGCAGCAACC
CATCTCATTC GCCACGCTGT GGGCAACAAC GAGTTTGGGA CTGTTGATCA TGAGCGCCTC
TCTAAAATGC TTAGTCTTCC TGAAGAGCTT GCTCGAATGT ACAGAGATGA CATTACAATC
ATTGTAGTTC AGTTCAATTC TCATGTTGTA GGGGCGTATC AAAACCAAGA ATAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011515438.1
CDS230..1843
Misc Feature(1)554..1804(+)
Misc Feature(2)587..1777(+)
Translation
Position Chain Variation Link
50 50 c, t dbSNP:747925009
76 76 a, c dbSNP:769669407
98 98 g, t dbSNP:575578742
176 176 a, c dbSNP:779107192
188 188 a, g dbSNP:368896704
191 191 c, t dbSNP:745378971
203 203 c, t dbSNP:76597597
205 205 c, t dbSNP:771654817
206 206 a, t dbSNP:779914919
207 207 g, t dbSNP:746656680
215 215 -, t dbSNP:748745930
217 217 c, g dbSNP:373914341
220 220 a, c dbSNP:767109728
225 225 a, g dbSNP:763177277
226 226 a, t dbSNP:771499042
230 230 a, g dbSNP:774772187
234 234 c, t dbSNP:775877089
242 242 a, g dbSNP:759621538
243 243 c, g dbSNP:376864107
245 245 c, t dbSNP:775755715
247 247 a, c dbSNP:760854097
249 249 a, t dbSNP:763841975
251 251 c, t dbSNP:753700131
253 253 c, t dbSNP:756937580
254 254 c, t dbSNP:371323550
261 261 c, t dbSNP:765234818
266 266 c, t dbSNP:750372945
267 267 a, g dbSNP:758052799
276 276 a, t dbSNP:760929995
279 279 c, t dbSNP:746711864
285 285 a, g dbSNP:754684543
291 291 a, g dbSNP:780665993
295 295 c, t dbSNP:749664764
297 297 c, g dbSNP:771139058
302 302 c, t dbSNP:774892672
303 303 a, g dbSNP:746369657
313 313 c, t dbSNP:772178775
316 316 c, t dbSNP:758947272
320 320 c, t dbSNP:201452113
321 321 a, g, t dbSNP:764383471
340 340 a, c, g, t dbSNP:761727112
353 353 a, g dbSNP:758390717
356 356 c, t dbSNP:766372826
357 357 a, g dbSNP:201081450
359 359 c, g dbSNP:754376963
360 360 c, t dbSNP:780907656
374 374 c, t dbSNP:747738989
383 383 c, t dbSNP:140713866
412 412 c, t dbSNP:779217265
424 424 c, t dbSNP:375147234
425 425 a, g dbSNP:569067471
430 430 a, c, g dbSNP:775911139
431 431 a, g dbSNP:374758737
441 441 a, g dbSNP:776979550
443 443 g, t dbSNP:761913953
444 444 c, t dbSNP:769765131
455 455 a, c dbSNP:773166625
468 468 c, t dbSNP:79439881
486 486 a, g dbSNP:762798871
490 490 c, t dbSNP:144544236
500 500 a, g dbSNP:751392690
503 503 a, g dbSNP:759139812
505 505 c, t dbSNP:766927852
506 506 g, t dbSNP:267606938
513 513 a, g dbSNP:368756677
535 535 c, t dbSNP:755698784
536 536 a, g dbSNP:777354361
554 554 a, g dbSNP:750815139
557 557 c, g dbSNP:758705968
571 571 c, g, t dbSNP:780597558
574 574 c, t dbSNP:768820696
580 580 g, t dbSNP:781113804
593 593 c, g dbSNP:748213138
596 596 a, c, g dbSNP:144604949
605 605 a, c, t dbSNP:565152013
606 606 a, g dbSNP:147845975
607 607 c, g dbSNP:759361135
626 626 c, t dbSNP:767102971
633 633 c, g dbSNP:752170333
634 634 c, t dbSNP:376531662
635 635 a, c dbSNP:201131767
647 647 c, t dbSNP:141399719
650 650 a, g dbSNP:151019488
652 652 a, g dbSNP:368265235
654 654 -, t dbSNP:768282589
712 712 c, t dbSNP:758829356
721 721 g, t dbSNP:780250994
722 722 a, g dbSNP:752161030
730 730 a, g, t dbSNP:755465648
739 739 a, t dbSNP:200661557
744 744 c, t dbSNP:750529031
764 764 a, g dbSNP:769934912
765 765 c, g, t dbSNP:778196214
766 766 a, g dbSNP:770886339
770 770 c, g dbSNP:773995220
775 775 c, t dbSNP:202034256
778 778 c, t dbSNP:771933821
779 779 c, t dbSNP:775429341
780 780 a, g dbSNP:760238687
785 785 c, t dbSNP:763591084
786 786 c, g, t dbSNP:572895007
799 799 c, t dbSNP:764899090
829 829 a, c, t dbSNP:541907484
839 839 a, g dbSNP:767925776
852 852 a, g dbSNP:753240948
870 870 c, t dbSNP:200145429
880 880 a, g dbSNP:777966209
883 883 a, g dbSNP:749570505
886 886 c, t dbSNP:374859758
898 898 c, t dbSNP:138512618
900 900 c, t dbSNP:140780685
907 907 c, g dbSNP:199977411
909 909 c, t dbSNP:771889434
910 910 a, g dbSNP:369055053
913 913 c, t dbSNP:757895185
918 918 c, g, t dbSNP:201467137
919 919 c, t dbSNP:776144330
922 922 c, t dbSNP:761277113
934 934 g, t dbSNP:764804506
935 935 c, t dbSNP:772866221
946 946 c, g dbSNP:150112501
967 967 c, t dbSNP:767917111
982 982 a, g dbSNP:138553326
1005 1005 g, t dbSNP:750473319
1006 1006 g, t dbSNP:753292297
1009 1009 c, t dbSNP:140224111
1011 1011 a, g dbSNP:145915456
1014 1014 a, c dbSNP:754001678
1026 1026 a, g dbSNP:757292942
1033 1033 a, g dbSNP:779015042
1036 1036 a, t dbSNP:746100755
1045 1045 c, t dbSNP:758169742
1057 1057 a, g dbSNP:779802119
1060 1060 c, t dbSNP:746758163
1076 1076 g, t dbSNP:768615485
1084 1084 c, t dbSNP:201021364
1092 1092 a, g dbSNP:747673653
1099 1099 c, t dbSNP:561440517
1100 1100 a, g dbSNP:772803719
1107 1107 a, g dbSNP:762632055
1115 1115 c, g dbSNP:758604713
1121 1121 a, g dbSNP:373016029
1126 1126 a, g dbSNP:776018911
1127 1127 c, g dbSNP:780162130
1129 1129 a, g dbSNP:761080494
1135 1135 c, t dbSNP:138488258
1138 1138 c, t dbSNP:146222349
1142 1142 c, t dbSNP:149633208
1148 1148 g, t dbSNP:765330955
1155 1155 c, t dbSNP:750660703
1156 1156 a, g dbSNP:758670020
1166 1166 a, g dbSNP:780213686
1173 1173 a, g dbSNP:751365113
1180 1180 a, g dbSNP:754713600
1196 1196 a, g dbSNP:370143029
1200 1200 a, g dbSNP:748108713
1208 1208 c, t dbSNP:373354872
1209 1209 g, t dbSNP:529355400
1222 1222 a, g dbSNP:200054483
1230 1230 c, g dbSNP:770737506
1231 1231 c, g dbSNP:774080309
1240 1240 c, t dbSNP:761133347
1241 1241 a, g dbSNP:769128065
1250 1250 c, g dbSNP:144339806
1253 1253 c, t dbSNP:762362258
1258 1258 c, g dbSNP:755900273
1259 1259 c, t dbSNP:534701211
1262 1262 -, g dbSNP:774046054
1297 1297 a, g dbSNP:769050733
1319 1319 c, g dbSNP:750548247
1333 1333 a, g dbSNP:762878527
1336 1336 a, g dbSNP:766605438
1348 1348 a, g dbSNP:751770350
1358 1358 a, t dbSNP:754838278
1359 1359 a, g dbSNP:780930808
1372 1372 c, t dbSNP:752624152
1382 1382 a, t dbSNP:777603105
1387 1387 c, t dbSNP:777530209
1398 1398 a, c dbSNP:748834473
1400 1400 a, t dbSNP:756767503
1405 1405 g, t dbSNP:778764676
1411 1411 c, t dbSNP:745485872
1433 1433 a, g dbSNP:769193664
1438 1438 c, t dbSNP:777075890
1442 1442 c, t dbSNP:377342640
1443 1443 a, g dbSNP:770342233
1457 1457 g, t dbSNP:369447724
1458 1458 a, g dbSNP:763153521
1462 1462 a, g dbSNP:374326474
1471 1471 a, g dbSNP:148348306
1480 1480 c, t dbSNP:774592444
1487 1487 g, t dbSNP:759729815
1496 1496 a, g dbSNP:767674134
1503 1503 a, g dbSNP:200222464
1510 1510 a, c, g dbSNP:141493326
1513 1513 c, t dbSNP:753703262
1533 1533 a, g dbSNP:756892474
1540 1540 a, t dbSNP:778545811
1545 1545 a, g dbSNP:745323862
1547 1547 a, g dbSNP:758156720
1551 1551 a, g dbSNP:779506684
1558 1558 a, c dbSNP:748562555
1570 1570 g, t dbSNP:770046269
1571 1571 a, g dbSNP:749168775
1583 1583 a, g dbSNP:773838560
1584 1584 a, g dbSNP:749767366
1585 1585 a, g dbSNP:771044295
1592 1592 c, g dbSNP:373946288
1595 1595 a, g dbSNP:759570204
1604 1604 c, g dbSNP:767783621
1609 1609 -, cctttta dbSNP:747806749
1622 1622 a, g dbSNP:775515661
1627 1627 a, g dbSNP:760576538
1629 1629 c, g dbSNP:763792118
1631 1631 a, g dbSNP:377553463
1642 1642 a, g dbSNP:757283913
1646 1646 c, t dbSNP:201132164
1652 1652 g, t dbSNP:749959908
1654 1654 a, t dbSNP:757927785
1658 1658 a, g dbSNP:779817145
1660 1660 c, t dbSNP:147477305
1661 1661 a, g dbSNP:756545344
1663 1663 a, g dbSNP:117294206
1675 1675 a, c, t dbSNP:137975172
1676 1676 a, g dbSNP:370390664
1679 1679 c, t dbSNP:745958515
1684 1684 c, t dbSNP:374262682
1690 1690 a, g dbSNP:775848242
1695 1695 a, g dbSNP:760776715
1699 1699 c, t dbSNP:768875523
1710 1710 c, t dbSNP:776599018
1724 1724 c, t dbSNP:761636189
1725 1725 a, g dbSNP:376060350
1731 1731 c, g dbSNP:750375166
1732 1732 c, t dbSNP:762593464
1749 1749 c, g dbSNP:145358369
1756 1756 a, g dbSNP:751277921
1763 1763 c, t dbSNP:202225648
1774 1774 a, g dbSNP:754605931
1787 1787 a, g dbSNP:202145000
1796 1796 c, g dbSNP:754204252
1799 1799 c, g dbSNP:147237491
1806 1806 a, g dbSNP:779452040
1808 1808 c, t dbSNP:746369671
1814 1814 g, t dbSNP:772232968
1817 1817 a, g dbSNP:780020258
1819 1819 -, g dbSNP:772846653
1822 1822 a, g dbSNP:747071043
1824 1824 c, t dbSNP:768767735
1825 1825 a, g dbSNP:535568386
1843 1843 c, g dbSNP:139199750
1844 1844 c, t dbSNP:761761105
1845 1845 c, g dbSNP:769711015
1857 1857 c, t dbSNP:773326652
1859 1859 a, c dbSNP:762781777
1863 1863 c, g dbSNP:766287359
1865 1865 a, g dbSNP:555465685
1868 1868 c, g dbSNP:41272415
1874 1874 c, t dbSNP:759016944
1879 1879 c, t dbSNP:4735258
1880 1880 a, g dbSNP:752331175
1881 1881 c, t dbSNP:757684185
1882 1882 a, g dbSNP:765555188
1889 1889 a, g, t dbSNP:750976092
1892 1892 a, c dbSNP:192535454
1894 1894 g, t dbSNP:149521176
1902 1902 a, t dbSNP:540479716
1908 1908 a, g dbSNP:144036151
1914 1914 c, t dbSNP:148691545
1925 1925 a, g dbSNP:542596810
1936 1936 a, g dbSNP:144473673
2000 2000 -, a dbSNP:760027289
2023 2023 c, t dbSNP:577643189
2134 2134 a, g dbSNP:769186837
2144 2144 a, g dbSNP:531689009
2211 2211 c, g dbSNP:551728387
2216 2216 c, t dbSNP:185126352
2236 2236 c, t dbSNP:527981638
2263 2263 c, t dbSNP:548043412
2295 2295 c, t dbSNP:566488276
2301 2301 a, t dbSNP:535475031
2334 2334 g, t dbSNP:41272417
2352 2352 a, c, g dbSNP:199846257
2409 2409 c, t dbSNP:78884124
2435 2435 a, g dbSNP:537935933
2441 2441 c, t dbSNP:557676479
2453 2453 a, g dbSNP:190420045
2464 2464 a, g dbSNP:545692596
2472 2472 a, g dbSNP:192629673
2474 2474 c, g dbSNP:911
2482 2482 a, g dbSNP:147461233
2488 2488 c, g dbSNP:762341289
2498 2498 a, g dbSNP:185015320
2509 2509 -, g dbSNP:139623857
2546 2546 a, g dbSNP:562533870
2554 2554 a, g dbSNP:554502999
2570 2570 c, t dbSNP:545440707
2650 2650 a, c dbSNP:188727327
2655 2655 a, g dbSNP:765693471
2701 2701 c, t dbSNP:750465585
2702 2702 a, g dbSNP:527854224
2717 2717 g, t dbSNP:572912702
2729 2729 c, t dbSNP:547657737
2741 2741 -, ctt dbSNP:756226872
2753 2753 a, t dbSNP:7461396
2773 2773 a, g dbSNP:180752222
2800 2800 a, g dbSNP:75265995
2845 2845 -, g dbSNP:35866235
2850 2850 a, g dbSNP:185360919
2872 2872 c, g dbSNP:762919416
2934 2934 a, c dbSNP:568829851
2943 2943 a, g dbSNP:540442395
2956 2956 c, t dbSNP:537546709
2957 2957 a, g dbSNP:551427862
2970 2970 c, t dbSNP:766520277
3046 3046 -, g dbSNP:35793146
3071 3071 a, c dbSNP:571367515
3082 3082 a, c dbSNP:751718373
3093 3093 a, g dbSNP:534020211
3167 3167 a, c, g dbSNP:774244422
3176 3176 a, g dbSNP:553548239
3184 3184 g, t dbSNP:573640783
3193 3193 c, t dbSNP:561592504
3249 3249 a, c dbSNP:753665809
3252 3252 a, g dbSNP:757140568
3262 3262 a, c dbSNP:201779185
3285 3285 a, g dbSNP:748740342
3330 3330 a, t dbSNP:189435075
3339 3339 a, t dbSNP:576359274
3354 3354 c, t dbSNP:745862328
3360 3360 a, g dbSNP:545190275
3381 3381 c, t dbSNP:771482216
3392 3392 c, t dbSNP:565409416
3394 3394 g, t dbSNP:779668197
3407 3407 a, c dbSNP:111728711
3452 3452 a, g dbSNP:186669527
3491 3491 -, t dbSNP:778564057
3491 3491 -, g dbSNP:145384326
3492 3492 g, t dbSNP:377214447
3493 3493 g, t dbSNP:192025344
3504 3504 -, t dbSNP:60316663
3507 3507 a, g dbSNP:558897089
3533 3533 a, g dbSNP:777095381
3563 3563 a, g dbSNP:566314054
3579 3579 c, g dbSNP:116788695
3605 3605 c, t dbSNP:568255963
3631 3631 -, c dbSNP:753816030
3642 3642 c, g dbSNP:535028389
3646 3646 c, g dbSNP:773560152
3648 3648 a, g dbSNP:531302765
3650 3650 a, t dbSNP:77734416
3673 3673 c, g dbSNP:571368323
3680 3680 a, g dbSNP:533642903
3689 3689 a, g dbSNP:537145163
3701 3701 a, g dbSNP:767466121
3712 3712 a, g dbSNP:553341714
3749 3749 g, t dbSNP:567078023
3765 3765 a, t dbSNP:139839619
3793 3793 c, t dbSNP:751645556
3918 3918 -, a dbSNP:368109978
3929 3929 a, g dbSNP:556007957
3938 3938 c, t dbSNP:115434133
4058 4058 g, t dbSNP:759715556
4073 4073 a, t dbSNP:767751976
4098 4098 c, t dbSNP:183503324
4100 4100 a, t dbSNP:367694582
4106 4106 c, t dbSNP:145337691
4143 4143 -, a dbSNP:539401507
4156 4156 g, t dbSNP:754099555
4179 4179 a, t dbSNP:186410170
4196 4196 g, t dbSNP:190113849
4228 4228 a, t dbSNP:557560034
4234 4234 -, c dbSNP:745781350

Target ORF information:

RefSeq Version XM_011517136
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011517136

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGCCAGCAC CAACTCAACT GTTTTTTCCT CTCATCCGTA ACTGTGAACT GAGCAGGATC 
TATGGCACTG CATGTTACTG CCACCACAAA CATCTCTGTT GTTCCTCATC GTACATTCCT
CAGAGTCGAC TGAGATACAC ACCTCATCCA GCATATGCTA CCTTTTGCAG GCCAAAGGAG
AACTGGTGGC AGTACACCCA AGGAAGGAGA TATGCTTCCA CACCACAGAA ATTTTACCTC
ACACCTCCAC AAGTCAATAG CATCCTTAAA GCTAATGAAT ACAGTTTCAA AGTGCCAGAA
TTTGACGGCA AAAATGTCAG TTCTATCCTT GGATTTGACA GCAATCAGCT GCCTGCAAAT
GCACCCATTG AGGACCGGAG AAGTGCAGCA ACCTGCTTGC AGACCAGAGG GATGCTTTTG
GGGGTTTTTG ATGGCCATGC AGGTTGTGCT TGTTCCCAGG CAGTCAGTGA AAGACTCTTT
TATTATATTG CTGTCTCTTT GTTACCCCAT GAGACTTTGC TAGAGATTGA AAATGCAGTG
GAGAGCGGCC GGGCACTGCT ACCCATTCTC CAGTGGCACA AGCACCCCAA TGATTACTTT
AGTAAGGAGG CATCCAAATT GTACTTTAAC AGCTTGAGGA CTTACTGGCA AGAGCTTATA
GACCTCAACA CTGGTGAGTC GACTGATATT GATGTTAAGG AGGCTCTAAT TAATGCCTTC
AAGAGGCTTG ATAATGACAT CTCCTTGGAG GCGCAAGTTG GTGATCCTAA TTCTTTTCTC
AACTACCTGG TGCTTCGAGT GGCATTTTCT GGAGCCACTG CTTGTGTGGC CCATGTGGAT
GGTGTTGACC TTCATGTGGC CAATACTGGC GATAGCAGAG CCATGCTGGG TGTGCAGGAA
GAGGACGGCT CATGGTCAGC AGTCACGCTG TCTAATGACC ACAATGCTCA AAATGAAAGA
GAACTAGAAC GGCTGAAATT GGAACATCCA AAGAGTGAGG CCAAGAGTGT CGTGAAACAG
GATCGGCTGC TTGGCTTGCT GATGCCATTT AGGGCATTTG GAGATGTAAA GTTCAAATGG
AGCATTGACC TTCAAAAGAG AGTGATAGAA TCTGGCCCAG ACCAGTTGAA TGACAATGAA
TATACCAAGT TTATTCCTCC TAATTATCAC ACACCTCCTT ATCTCACTGC TGAGCCAGAG
GTAACTTACC ACCGATTAAG GCCACAGGAT AAGTTTCTGG TGTTGGCTAC TGATGGGTTG
TGGGAGACTA TGCATAGGCA GGATGTGGTT AGGATTGTGG GTGAGTACCT AACTGGCATG
CATCACCAAC AGCCAATAGC TGTTGGTGGC TACAAGGTGA CTCTGGGACA GATGCATGGC
CTTTTAACAG AAAGGAGAAC CAAAATGTCC TCGGTATTTG AGGATCAGAA CGCAGCAACC
CATCTCATTC GCCACGCTGT GGGCAACAAC GAGTTTGGGA CTGTTGATCA TGAGCGCCTC
TCTAAAATGC TTAGTCTTCC TGAAGAGCTT GCTCGAATGT ACAGAGATGA CATTACAATC
ATTGTAGTTC AGTTCAATTC TCATGTTGTA GGGGCGTATC AAAACCAAGA ATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17481
Accession Version XM_011517137.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1614bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_008046.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGCCAGCAC CAACTCAACT GTTTTTTCCT CTCATCCGTA ACTGTGAACT GAGCAGGATC 
TATGGCACTG CATGTTACTG CCACCACAAA CATCTCTGTT GTTCCTCATC GTACATTCCT
CAGAGTCGAC TGAGATACAC ACCTCATCCA GCATATGCTA CCTTTTGCAG GCCAAAGGAG
AACTGGTGGC AGTACACCCA AGGAAGGAGA TATGCTTCCA CACCACAGAA ATTTTACCTC
ACACCTCCAC AAGTCAATAG CATCCTTAAA GCTAATGAAT ACAGTTTCAA AGTGCCAGAA
TTTGACGGCA AAAATGTCAG TTCTATCCTT GGATTTGACA GCAATCAGCT GCCTGCAAAT
GCACCCATTG AGGACCGGAG AAGTGCAGCA ACCTGCTTGC AGACCAGAGG GATGCTTTTG
GGGGTTTTTG ATGGCCATGC AGGTTGTGCT TGTTCCCAGG CAGTCAGTGA AAGACTCTTT
TATTATATTG CTGTCTCTTT GTTACCCCAT GAGACTTTGC TAGAGATTGA AAATGCAGTG
GAGAGCGGCC GGGCACTGCT ACCCATTCTC CAGTGGCACA AGCACCCCAA TGATTACTTT
AGTAAGGAGG CATCCAAATT GTACTTTAAC AGCTTGAGGA CTTACTGGCA AGAGCTTATA
GACCTCAACA CTGGTGAGTC GACTGATATT GATGTTAAGG AGGCTCTAAT TAATGCCTTC
AAGAGGCTTG ATAATGACAT CTCCTTGGAG GCGCAAGTTG GTGATCCTAA TTCTTTTCTC
AACTACCTGG TGCTTCGAGT GGCATTTTCT GGAGCCACTG CTTGTGTGGC CCATGTGGAT
GGTGTTGACC TTCATGTGGC CAATACTGGC GATAGCAGAG CCATGCTGGG TGTGCAGGAA
GAGGACGGCT CATGGTCAGC AGTCACGCTG TCTAATGACC ACAATGCTCA AAATGAAAGA
GAACTAGAAC GGCTGAAATT GGAACATCCA AAGAGTGAGG CCAAGAGTGT CGTGAAACAG
GATCGGCTGC TTGGCTTGCT GATGCCATTT AGGGCATTTG GAGATGTAAA GTTCAAATGG
AGCATTGACC TTCAAAAGAG AGTGATAGAA TCTGGCCCAG ACCAGTTGAA TGACAATGAA
TATACCAAGT TTATTCCTCC TAATTATCAC ACACCTCCTT ATCTCACTGC TGAGCCAGAG
GTAACTTACC ACCGATTAAG GCCACAGGAT AAGTTTCTGG TGTTGGCTAC TGATGGGTTG
TGGGAGACTA TGCATAGGCA GGATGTGGTT AGGATTGTGG GTGAGTACCT AACTGGCATG
CATCACCAAC AGCCAATAGC TGTTGGTGGC TACAAGGTGA CTCTGGGACA GATGCATGGC
CTTTTAACAG AAAGGAGAAC CAAAATGTCC TCGGTATTTG AGGATCAGAA CGCAGCAACC
CATCTCATTC GCCACGCTGT GGGCAACAAC GAGTTTGGGA CTGTTGATCA TGAGCGCCTC
TCTAAAATGC TTAGTCTTCC TGAAGAGCTT GCTCGAATGT ACAGAGATGA CATTACAATC
ATTGTAGTTC AGTTCAATTC TCATGTTGTA GGGGCGTATC AAAACCAAGA ATAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011515439.1
CDS262..1875
Misc Feature(1)586..1836(+)
Misc Feature(2)619..1809(+)
Translation
Position Chain Variation Link
1 1 c, t dbSNP:749406937
3 3 a, t dbSNP:771064281
4 4 a, g dbSNP:779287937
6 6 a, g dbSNP:746071530
13 13 a, g dbSNP:771944772
16 16 c, g dbSNP:775128777
18 18 a, g dbSNP:760474141
30 30 c, t dbSNP:768510527
47 47 g, t dbSNP:776484586
50 50 a, g dbSNP:761326355
51 51 a, g dbSNP:764715116
52 52 a, g dbSNP:532831481
54 54 c, g dbSNP:762480054
58 58 a, c dbSNP:372548037
59 59 a, g dbSNP:753025018
74 74 a, g dbSNP:756461276
80 80 a, g dbSNP:764697879
82 82 c, t dbSNP:747925009
108 108 a, c dbSNP:769669407
130 130 g, t dbSNP:575578742
208 208 a, c dbSNP:779107192
220 220 a, g dbSNP:368896704
223 223 c, t dbSNP:745378971
235 235 c, t dbSNP:76597597
237 237 c, t dbSNP:771654817
238 238 a, t dbSNP:779914919
239 239 g, t dbSNP:746656680
247 247 -, t dbSNP:748745930
249 249 c, g dbSNP:373914341
252 252 a, c dbSNP:767109728
257 257 a, g dbSNP:763177277
258 258 a, t dbSNP:771499042
262 262 a, g dbSNP:774772187
266 266 c, t dbSNP:775877089
274 274 a, g dbSNP:759621538
275 275 c, g dbSNP:376864107
277 277 c, t dbSNP:775755715
279 279 a, c dbSNP:760854097
281 281 a, t dbSNP:763841975
283 283 c, t dbSNP:753700131
285 285 c, t dbSNP:756937580
286 286 c, t dbSNP:371323550
293 293 c, t dbSNP:765234818
298 298 c, t dbSNP:750372945
299 299 a, g dbSNP:758052799
308 308 a, t dbSNP:760929995
311 311 c, t dbSNP:746711864
317 317 a, g dbSNP:754684543
323 323 a, g dbSNP:780665993
327 327 c, t dbSNP:749664764
329 329 c, g dbSNP:771139058
334 334 c, t dbSNP:774892672
335 335 a, g dbSNP:746369657
345 345 c, t dbSNP:772178775
348 348 c, t dbSNP:758947272
352 352 c, t dbSNP:201452113
353 353 a, g, t dbSNP:764383471
372 372 a, c, g, t dbSNP:761727112
385 385 a, g dbSNP:758390717
388 388 c, t dbSNP:766372826
389 389 a, g dbSNP:201081450
391 391 c, g dbSNP:754376963
392 392 c, t dbSNP:780907656
406 406 c, t dbSNP:747738989
415 415 c, t dbSNP:140713866
444 444 c, t dbSNP:779217265
456 456 c, t dbSNP:375147234
457 457 a, g dbSNP:569067471
462 462 a, c, g dbSNP:775911139
463 463 a, g dbSNP:374758737
473 473 a, g dbSNP:776979550
475 475 g, t dbSNP:761913953
476 476 c, t dbSNP:769765131
487 487 a, c dbSNP:773166625
500 500 c, t dbSNP:79439881
518 518 a, g dbSNP:762798871
522 522 c, t dbSNP:144544236
532 532 a, g dbSNP:751392690
535 535 a, g dbSNP:759139812
537 537 c, t dbSNP:766927852
538 538 g, t dbSNP:267606938
545 545 a, g dbSNP:368756677
567 567 c, t dbSNP:755698784
568 568 a, g dbSNP:777354361
586 586 a, g dbSNP:750815139
589 589 c, g dbSNP:758705968
603 603 c, g, t dbSNP:780597558
606 606 c, t dbSNP:768820696
612 612 g, t dbSNP:781113804
625 625 c, g dbSNP:748213138
628 628 a, c, g dbSNP:144604949
637 637 a, c, t dbSNP:565152013
638 638 a, g dbSNP:147845975
639 639 c, g dbSNP:759361135
658 658 c, t dbSNP:767102971
665 665 c, g dbSNP:752170333
666 666 c, t dbSNP:376531662
667 667 a, c dbSNP:201131767
679 679 c, t dbSNP:141399719
682 682 a, g dbSNP:151019488
684 684 a, g dbSNP:368265235
686 686 -, t dbSNP:768282589
744 744 c, t dbSNP:758829356
753 753 g, t dbSNP:780250994
754 754 a, g dbSNP:752161030
762 762 a, g, t dbSNP:755465648
771 771 a, t dbSNP:200661557
776 776 c, t dbSNP:750529031
796 796 a, g dbSNP:769934912
797 797 c, g, t dbSNP:778196214
798 798 a, g dbSNP:770886339
802 802 c, g dbSNP:773995220
807 807 c, t dbSNP:202034256
810 810 c, t dbSNP:771933821
811 811 c, t dbSNP:775429341
812 812 a, g dbSNP:760238687
817 817 c, t dbSNP:763591084
818 818 c, g, t dbSNP:572895007
831 831 c, t dbSNP:764899090
861 861 a, c, t dbSNP:541907484
871 871 a, g dbSNP:767925776
884 884 a, g dbSNP:753240948
902 902 c, t dbSNP:200145429
912 912 a, g dbSNP:777966209
915 915 a, g dbSNP:749570505
918 918 c, t dbSNP:374859758
930 930 c, t dbSNP:138512618
932 932 c, t dbSNP:140780685
939 939 c, g dbSNP:199977411
941 941 c, t dbSNP:771889434
942 942 a, g dbSNP:369055053
945 945 c, t dbSNP:757895185
950 950 c, g, t dbSNP:201467137
951 951 c, t dbSNP:776144330
954 954 c, t dbSNP:761277113
966 966 g, t dbSNP:764804506
967 967 c, t dbSNP:772866221
978 978 c, g dbSNP:150112501
999 999 c, t dbSNP:767917111
1014 1014 a, g dbSNP:138553326
1037 1037 g, t dbSNP:750473319
1038 1038 g, t dbSNP:753292297
1041 1041 c, t dbSNP:140224111
1043 1043 a, g dbSNP:145915456
1046 1046 a, c dbSNP:754001678
1058 1058 a, g dbSNP:757292942
1065 1065 a, g dbSNP:779015042
1068 1068 a, t dbSNP:746100755
1077 1077 c, t dbSNP:758169742
1089 1089 a, g dbSNP:779802119
1092 1092 c, t dbSNP:746758163
1108 1108 g, t dbSNP:768615485
1116 1116 c, t dbSNP:201021364
1124 1124 a, g dbSNP:747673653
1131 1131 c, t dbSNP:561440517
1132 1132 a, g dbSNP:772803719
1139 1139 a, g dbSNP:762632055
1147 1147 c, g dbSNP:758604713
1153 1153 a, g dbSNP:373016029
1158 1158 a, g dbSNP:776018911
1159 1159 c, g dbSNP:780162130
1161 1161 a, g dbSNP:761080494
1167 1167 c, t dbSNP:138488258
1170 1170 c, t dbSNP:146222349
1174 1174 c, t dbSNP:149633208
1180 1180 g, t dbSNP:765330955
1187 1187 c, t dbSNP:750660703
1188 1188 a, g dbSNP:758670020
1198 1198 a, g dbSNP:780213686
1205 1205 a, g dbSNP:751365113
1212 1212 a, g dbSNP:754713600
1228 1228 a, g dbSNP:370143029
1232 1232 a, g dbSNP:748108713
1240 1240 c, t dbSNP:373354872
1241 1241 g, t dbSNP:529355400
1254 1254 a, g dbSNP:200054483
1262 1262 c, g dbSNP:770737506
1263 1263 c, g dbSNP:774080309
1272 1272 c, t dbSNP:761133347
1273 1273 a, g dbSNP:769128065
1282 1282 c, g dbSNP:144339806
1285 1285 c, t dbSNP:762362258
1290 1290 c, g dbSNP:755900273
1291 1291 c, t dbSNP:534701211
1294 1294 -, g dbSNP:774046054
1329 1329 a, g dbSNP:769050733
1351 1351 c, g dbSNP:750548247
1365 1365 a, g dbSNP:762878527
1368 1368 a, g dbSNP:766605438
1380 1380 a, g dbSNP:751770350
1390 1390 a, t dbSNP:754838278
1391 1391 a, g dbSNP:780930808
1404 1404 c, t dbSNP:752624152
1414 1414 a, t dbSNP:777603105
1419 1419 c, t dbSNP:777530209
1430 1430 a, c dbSNP:748834473
1432 1432 a, t dbSNP:756767503
1437 1437 g, t dbSNP:778764676
1443 1443 c, t dbSNP:745485872
1465 1465 a, g dbSNP:769193664
1470 1470 c, t dbSNP:777075890
1474 1474 c, t dbSNP:377342640
1475 1475 a, g dbSNP:770342233
1489 1489 g, t dbSNP:369447724
1490 1490 a, g dbSNP:763153521
1494 1494 a, g dbSNP:374326474
1503 1503 a, g dbSNP:148348306
1512 1512 c, t dbSNP:774592444
1519 1519 g, t dbSNP:759729815
1528 1528 a, g dbSNP:767674134
1535 1535 a, g dbSNP:200222464
1542 1542 a, c, g dbSNP:141493326
1545 1545 c, t dbSNP:753703262
1565 1565 a, g dbSNP:756892474
1572 1572 a, t dbSNP:778545811
1577 1577 a, g dbSNP:745323862
1579 1579 a, g dbSNP:758156720
1583 1583 a, g dbSNP:779506684
1590 1590 a, c dbSNP:748562555
1602 1602 g, t dbSNP:770046269
1603 1603 a, g dbSNP:749168775
1615 1615 a, g dbSNP:773838560
1616 1616 a, g dbSNP:749767366
1617 1617 a, g dbSNP:771044295
1624 1624 c, g dbSNP:373946288
1627 1627 a, g dbSNP:759570204
1636 1636 c, g dbSNP:767783621
1641 1641 -, cctttta dbSNP:747806749
1654 1654 a, g dbSNP:775515661
1659 1659 a, g dbSNP:760576538
1661 1661 c, g dbSNP:763792118
1663 1663 a, g dbSNP:377553463
1674 1674 a, g dbSNP:757283913
1678 1678 c, t dbSNP:201132164
1684 1684 g, t dbSNP:749959908
1686 1686 a, t dbSNP:757927785
1690 1690 a, g dbSNP:779817145
1692 1692 c, t dbSNP:147477305
1693 1693 a, g dbSNP:756545344
1695 1695 a, g dbSNP:117294206
1707 1707 a, c, t dbSNP:137975172
1708 1708 a, g dbSNP:370390664
1711 1711 c, t dbSNP:745958515
1716 1716 c, t dbSNP:374262682
1722 1722 a, g dbSNP:775848242
1727 1727 a, g dbSNP:760776715
1731 1731 c, t dbSNP:768875523
1742 1742 c, t dbSNP:776599018
1756 1756 c, t dbSNP:761636189
1757 1757 a, g dbSNP:376060350
1763 1763 c, g dbSNP:750375166
1764 1764 c, t dbSNP:762593464
1781 1781 c, g dbSNP:145358369
1788 1788 a, g dbSNP:751277921
1795 1795 c, t dbSNP:202225648
1806 1806 a, g dbSNP:754605931
1819 1819 a, g dbSNP:202145000
1828 1828 c, g dbSNP:754204252
1831 1831 c, g dbSNP:147237491
1838 1838 a, g dbSNP:779452040
1840 1840 c, t dbSNP:746369671
1846 1846 g, t dbSNP:772232968
1849 1849 a, g dbSNP:780020258
1851 1851 -, g dbSNP:772846653
1854 1854 a, g dbSNP:747071043
1856 1856 c, t dbSNP:768767735
1857 1857 a, g dbSNP:535568386
1875 1875 c, g dbSNP:139199750
1876 1876 c, t dbSNP:761761105
1877 1877 c, g dbSNP:769711015
1889 1889 c, t dbSNP:773326652
1891 1891 a, c dbSNP:762781777
1895 1895 c, g dbSNP:766287359
1897 1897 a, g dbSNP:555465685
1900 1900 c, g dbSNP:41272415
1906 1906 c, t dbSNP:759016944
1911 1911 c, t dbSNP:4735258
1912 1912 a, g dbSNP:752331175
1913 1913 c, t dbSNP:757684185
1914 1914 a, g dbSNP:765555188
1921 1921 a, g, t dbSNP:750976092
1924 1924 a, c dbSNP:192535454
1926 1926 g, t dbSNP:149521176
1934 1934 a, t dbSNP:540479716
1940 1940 a, g dbSNP:144036151
1946 1946 c, t dbSNP:148691545
1957 1957 a, g dbSNP:542596810
1968 1968 a, g dbSNP:144473673
2032 2032 -, a dbSNP:760027289
2055 2055 c, t dbSNP:577643189
2166 2166 a, g dbSNP:769186837
2176 2176 a, g dbSNP:531689009
2243 2243 c, g dbSNP:551728387
2248 2248 c, t dbSNP:185126352
2268 2268 c, t dbSNP:527981638
2295 2295 c, t dbSNP:548043412
2327 2327 c, t dbSNP:566488276
2333 2333 a, t dbSNP:535475031
2366 2366 g, t dbSNP:41272417
2384 2384 a, c, g dbSNP:199846257
2441 2441 c, t dbSNP:78884124
2467 2467 a, g dbSNP:537935933
2473 2473 c, t dbSNP:557676479
2485 2485 a, g dbSNP:190420045
2496 2496 a, g dbSNP:545692596
2504 2504 a, g dbSNP:192629673
2506 2506 c, g dbSNP:911
2514 2514 a, g dbSNP:147461233
2520 2520 c, g dbSNP:762341289
2530 2530 a, g dbSNP:185015320
2541 2541 -, g dbSNP:139623857
2578 2578 a, g dbSNP:562533870
2586 2586 a, g dbSNP:554502999
2602 2602 c, t dbSNP:545440707
2682 2682 a, c dbSNP:188727327
2687 2687 a, g dbSNP:765693471
2733 2733 c, t dbSNP:750465585
2734 2734 a, g dbSNP:527854224
2749 2749 g, t dbSNP:572912702
2761 2761 c, t dbSNP:547657737
2773 2773 -, ctt dbSNP:756226872
2785 2785 a, t dbSNP:7461396
2805 2805 a, g dbSNP:180752222
2832 2832 a, g dbSNP:75265995
2877 2877 -, g dbSNP:35866235
2882 2882 a, g dbSNP:185360919
2904 2904 c, g dbSNP:762919416
2966 2966 a, c dbSNP:568829851
2975 2975 a, g dbSNP:540442395
2988 2988 c, t dbSNP:537546709
2989 2989 a, g dbSNP:551427862
3002 3002 c, t dbSNP:766520277
3078 3078 -, g dbSNP:35793146
3103 3103 a, c dbSNP:571367515
3114 3114 a, c dbSNP:751718373
3125 3125 a, g dbSNP:534020211
3199 3199 a, c, g dbSNP:774244422
3208 3208 a, g dbSNP:553548239
3216 3216 g, t dbSNP:573640783
3225 3225 c, t dbSNP:561592504
3281 3281 a, c dbSNP:753665809
3284 3284 a, g dbSNP:757140568
3294 3294 a, c dbSNP:201779185
3317 3317 a, g dbSNP:748740342
3362 3362 a, t dbSNP:189435075
3371 3371 a, t dbSNP:576359274
3386 3386 c, t dbSNP:745862328
3392 3392 a, g dbSNP:545190275
3413 3413 c, t dbSNP:771482216
3424 3424 c, t dbSNP:565409416
3426 3426 g, t dbSNP:779668197
3439 3439 a, c dbSNP:111728711
3484 3484 a, g dbSNP:186669527
3523 3523 -, t dbSNP:778564057
3523 3523 -, g dbSNP:145384326
3524 3524 g, t dbSNP:377214447
3525 3525 g, t dbSNP:192025344
3536 3536 -, t dbSNP:60316663
3539 3539 a, g dbSNP:558897089
3565 3565 a, g dbSNP:777095381
3595 3595 a, g dbSNP:566314054
3611 3611 c, g dbSNP:116788695
3637 3637 c, t dbSNP:568255963
3663 3663 -, c dbSNP:753816030
3674 3674 c, g dbSNP:535028389
3678 3678 c, g dbSNP:773560152
3680 3680 a, g dbSNP:531302765
3682 3682 a, t dbSNP:77734416
3705 3705 c, g dbSNP:571368323
3712 3712 a, g dbSNP:533642903
3721 3721 a, g dbSNP:537145163
3733 3733 a, g dbSNP:767466121
3744 3744 a, g dbSNP:553341714
3781 3781 g, t dbSNP:567078023
3797 3797 a, t dbSNP:139839619
3825 3825 c, t dbSNP:751645556
3950 3950 -, a dbSNP:368109978
3961 3961 a, g dbSNP:556007957
3970 3970 c, t dbSNP:115434133
4090 4090 g, t dbSNP:759715556
4105 4105 a, t dbSNP:767751976
4130 4130 c, t dbSNP:183503324
4132 4132 a, t dbSNP:367694582
4138 4138 c, t dbSNP:145337691
4175 4175 -, a dbSNP:539401507
4188 4188 g, t dbSNP:754099555
4211 4211 a, t dbSNP:186410170
4228 4228 g, t dbSNP:190113849
4260 4260 a, t dbSNP:557560034
4266 4266 -, c dbSNP:745781350

Target ORF information:

RefSeq Version XM_011517137
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011517137

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGCCAGCAC CAACTCAACT GTTTTTTCCT CTCATCCGTA ACTGTGAACT GAGCAGGATC 
TATGGCACTG CATGTTACTG CCACCACAAA CATCTCTGTT GTTCCTCATC GTACATTCCT
CAGAGTCGAC TGAGATACAC ACCTCATCCA GCATATGCTA CCTTTTGCAG GCCAAAGGAG
AACTGGTGGC AGTACACCCA AGGAAGGAGA TATGCTTCCA CACCACAGAA ATTTTACCTC
ACACCTCCAC AAGTCAATAG CATCCTTAAA GCTAATGAAT ACAGTTTCAA AGTGCCAGAA
TTTGACGGCA AAAATGTCAG TTCTATCCTT GGATTTGACA GCAATCAGCT GCCTGCAAAT
GCACCCATTG AGGACCGGAG AAGTGCAGCA ACCTGCTTGC AGACCAGAGG GATGCTTTTG
GGGGTTTTTG ATGGCCATGC AGGTTGTGCT TGTTCCCAGG CAGTCAGTGA AAGACTCTTT
TATTATATTG CTGTCTCTTT GTTACCCCAT GAGACTTTGC TAGAGATTGA AAATGCAGTG
GAGAGCGGCC GGGCACTGCT ACCCATTCTC CAGTGGCACA AGCACCCCAA TGATTACTTT
AGTAAGGAGG CATCCAAATT GTACTTTAAC AGCTTGAGGA CTTACTGGCA AGAGCTTATA
GACCTCAACA CTGGTGAGTC GACTGATATT GATGTTAAGG AGGCTCTAAT TAATGCCTTC
AAGAGGCTTG ATAATGACAT CTCCTTGGAG GCGCAAGTTG GTGATCCTAA TTCTTTTCTC
AACTACCTGG TGCTTCGAGT GGCATTTTCT GGAGCCACTG CTTGTGTGGC CCATGTGGAT
GGTGTTGACC TTCATGTGGC CAATACTGGC GATAGCAGAG CCATGCTGGG TGTGCAGGAA
GAGGACGGCT CATGGTCAGC AGTCACGCTG TCTAATGACC ACAATGCTCA AAATGAAAGA
GAACTAGAAC GGCTGAAATT GGAACATCCA AAGAGTGAGG CCAAGAGTGT CGTGAAACAG
GATCGGCTGC TTGGCTTGCT GATGCCATTT AGGGCATTTG GAGATGTAAA GTTCAAATGG
AGCATTGACC TTCAAAAGAG AGTGATAGAA TCTGGCCCAG ACCAGTTGAA TGACAATGAA
TATACCAAGT TTATTCCTCC TAATTATCAC ACACCTCCTT ATCTCACTGC TGAGCCAGAG
GTAACTTACC ACCGATTAAG GCCACAGGAT AAGTTTCTGG TGTTGGCTAC TGATGGGTTG
TGGGAGACTA TGCATAGGCA GGATGTGGTT AGGATTGTGG GTGAGTACCT AACTGGCATG
CATCACCAAC AGCCAATAGC TGTTGGTGGC TACAAGGTGA CTCTGGGACA GATGCATGGC
CTTTTAACAG AAAGGAGAAC CAAAATGTCC TCGGTATTTG AGGATCAGAA CGCAGCAACC
CATCTCATTC GCCACGCTGT GGGCAACAAC GAGTTTGGGA CTGTTGATCA TGAGCGCCTC
TCTAAAATGC TTAGTCTTCC TGAAGAGCTT GCTCGAATGT ACAGAGATGA CATTACAATC
ATTGTAGTTC AGTTCAATTC TCATGTTGTA GGGGCGTATC AAAACCAAGA ATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17459
Accession Version NM_001161780.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1689bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA507397.1, BC064978.1, AK126862.1 and BX099681.1. Summary: Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009]. Transcript Variant: This variant (3) lacks an internal segment in the 5' UTR, compared to variant 2. Variants 2 and 3 encode the same isoform 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: DA775855.1, BC064978.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGTGTGTGT GTCCCGGGCC CAGACGAATT GGAATCCCAG TCAGAAGTTC CAGCCTGCCA 
CTGTTCTCTG ATGCCATGCC AGCACCAACT CAACTGTTTT TTCCTCTCAT CCGTAACTGT
GAACTGAGCA GGATCTATGG CACTGCATGT TACTGCCACC ACAAACATCT CTGTTGTTCC
TCATCGTACA TTCCTCAGAG TCGACTGAGA TACACACCTC ATCCAGCATA TGCTACCTTT
TGCAGGCCAA AGGAGAACTG GTGGCAGTAC ACCCAAGGAA GGAGATATGC TTCCACACCA
CAGAAATTTT ACCTCACACC TCCACAAGTC AATAGCATCC TTAAAGCTAA TGAATACAGT
TTCAAAGTGC CAGAATTTGA CGGCAAAAAT GTCAGTTCTA TCCTTGGATT TGACAGCAAT
CAGCTGCCTG CAAATGCACC CATTGAGGAC CGGAGAAGTG CAGCAACCTG CTTGCAGACC
AGAGGGATGC TTTTGGGGGT TTTTGATGGC CATGCAGGTT GTGCTTGTTC CCAGGCAGTC
AGTGAAAGAC TCTTTTATTA TATTGCTGTC TCTTTGTTAC CCCATGAGAC TTTGCTAGAG
ATTGAAAATG CAGTGGAGAG CGGCCGGGCA CTGCTACCCA TTCTCCAGTG GCACAAGCAC
CCCAATGATT ACTTTAGTAA GGAGGCATCC AAATTGTACT TTAACAGCTT GAGGACTTAC
TGGCAAGAGC TTATAGACCT CAACACTGGT GAGTCGACTG ATATTGATGT TAAGGAGGCT
CTAATTAATG CCTTCAAGAG GCTTGATAAT GACATCTCCT TGGAGGCGCA AGTTGGTGAT
CCTAATTCTT TTCTCAACTA CCTGGTGCTT CGAGTGGCAT TTTCTGGAGC CACTGCTTGT
GTGGCCCATG TGGATGGTGT TGACCTTCAT GTGGCCAATA CTGGCGATAG CAGAGCCATG
CTGGGTGTGC AGGAAGAGGA CGGCTCATGG TCAGCAGTCA CGCTGTCTAA TGACCACAAT
GCTCAAAATG AAAGAGAACT AGAACGGCTG AAATTGGAAC ATCCAAAGAG TGAGGCCAAG
AGTGTCGTGA AACAGGATCG GCTGCTTGGC TTGCTGATGC CATTTAGGGC ATTTGGAGAT
GTAAAGTTCA AATGGAGCAT TGACCTTCAA AAGAGAGTGA TAGAATCTGG CCCAGACCAG
TTGAATGACA ATGAATATAC CAAGTTTATT CCTCCTAATT ATCACACACC TCCTTATCTC
ACTGCTGAGC CAGAGGTAAC TTACCACCGA TTAAGGCCAC AGGATAAGTT TCTGGTGTTG
GCTACTGATG GGTTGTGGGA GACTATGCAT AGGCAGGATG TGGTTAGGAT TGTGGGTGAG
TACCTAACTG GCATGCATCA CCAACAGCCA ATAGCTGTTG GTGGCTACAA GGTGACTCTG
GGACAGATGC ATGGCCTTTT AACAGAAAGG AGAACCAAAA TGTCCTCGGT ATTTGAGGAT
CAGAACGCAG CAACCCATCT CATTCGCCAC GCTGTGGGCA ACAACGAGTT TGGGACTGTT
GATCATGAGC GCCTCTCTAA AATGCTTAGT CTTCCTGAAG AGCTTGCTCG AATGTACAGA
GATGACATTA CAATCATTGT AGTTCAGTTC AATTCTCATG TTGTAGGGGC GTATCAAAAC
CAAGAATAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001155252.1
CDS151..1839
Misc Feature(1)550..1800(+)
Misc Feature(2)583..1773(+)
Exon (1)1..146
Gene:PDP1
Gene Synonym:
Exon (2)147..181
Gene:PDP1
Gene Synonym:
Exon (3)182..4234
Gene:PDP1
Gene Synonym:
Translation
Position Chain Variation Link
2 2 c, t dbSNP:753531431
3 3 a, c, g dbSNP:756885157
6 6 a, t dbSNP:751952560
7 7 a, g dbSNP:755268904
11 11 a, c dbSNP:781730023
13 13 c, t dbSNP:748591846
21 21 a, g dbSNP:769982392
27 27 -, g dbSNP:766339112
27 27 c, t dbSNP:777681394
28 28 a, g dbSNP:749570657
30 30 c, g, t dbSNP:771299570
31 31 g, t dbSNP:759405446
32 32 a, g dbSNP:771703282
33 33 -, ga dbSNP:752725428
39 39 c, t dbSNP:775552151
41 41 a, c, t dbSNP:570396595
45 45 c, g dbSNP:753371996
48 48 c, t dbSNP:761273137
49 49 a, g dbSNP:764874879
51 51 a, g dbSNP:750022171
53 53 c, g dbSNP:755429761
55 55 c, t dbSNP:202016823
61 61 a, g dbSNP:781404802
63 63 c, g, t dbSNP:527903830
64 64 a, c, t dbSNP:756556074
67 67 c, t dbSNP:749406937
69 69 a, t dbSNP:771064281
70 70 a, g dbSNP:779287937
72 72 a, g dbSNP:746071530
79 79 a, g dbSNP:771944772
82 82 c, g dbSNP:775128777
84 84 a, g dbSNP:760474141
96 96 c, t dbSNP:768510527
113 113 g, t dbSNP:776484586
116 116 a, g dbSNP:761326355
117 117 a, g dbSNP:764715116
118 118 a, g dbSNP:532831481
120 120 c, g dbSNP:762480054
124 124 a, c dbSNP:372548037
125 125 a, g dbSNP:753025018
140 140 a, g dbSNP:756461276
146 146 a, g dbSNP:764697879
151 151 -, tg dbSNP:756648979
152 152 -, tg dbSNP:746354729
152 152 c, t dbSNP:755168595
159 159 a, g dbSNP:781341112
160 160 c, t dbSNP:752519178
169 169 c, t dbSNP:755840386
173 173 a, g dbSNP:777581092
176 176 a, g dbSNP:749231431
184 184 a, g dbSNP:368896704
187 187 c, t dbSNP:745378971
199 199 c, t dbSNP:76597597
201 201 c, t dbSNP:771654817
202 202 a, t dbSNP:779914919
203 203 g, t dbSNP:746656680
211 211 -, t dbSNP:748745930
213 213 c, g dbSNP:373914341
216 216 a, c dbSNP:767109728
221 221 a, g dbSNP:763177277
222 222 a, t dbSNP:771499042
226 226 a, g dbSNP:774772187
230 230 c, t dbSNP:775877089
238 238 a, g dbSNP:759621538
239 239 c, g dbSNP:376864107
241 241 c, t dbSNP:775755715
243 243 a, c dbSNP:760854097
245 245 a, t dbSNP:763841975
247 247 c, t dbSNP:753700131
249 249 c, t dbSNP:756937580
250 250 c, t dbSNP:371323550
257 257 c, t dbSNP:765234818
262 262 c, t dbSNP:750372945
263 263 a, g dbSNP:758052799
272 272 a, t dbSNP:760929995
275 275 c, t dbSNP:746711864
281 281 a, g dbSNP:754684543
287 287 a, g dbSNP:780665993
291 291 c, t dbSNP:749664764
293 293 c, g dbSNP:771139058
298 298 c, t dbSNP:774892672
299 299 a, g dbSNP:746369657
309 309 c, t dbSNP:772178775
312 312 c, t dbSNP:758947272
316 316 c, t dbSNP:201452113
317 317 a, g, t dbSNP:764383471
336 336 a, c, g, t dbSNP:761727112
349 349 a, g dbSNP:758390717
352 352 c, t dbSNP:766372826
353 353 a, g dbSNP:201081450
355 355 c, g dbSNP:754376963
356 356 c, t dbSNP:780907656
370 370 c, t dbSNP:747738989
379 379 c, t dbSNP:140713866
408 408 c, t dbSNP:779217265
420 420 c, t dbSNP:375147234
421 421 a, g dbSNP:569067471
426 426 a, c, g dbSNP:775911139
427 427 a, g dbSNP:374758737
437 437 a, g dbSNP:776979550
439 439 g, t dbSNP:761913953
440 440 c, t dbSNP:769765131
451 451 a, c dbSNP:773166625
464 464 c, t dbSNP:79439881
482 482 a, g dbSNP:762798871
486 486 c, t dbSNP:144544236
496 496 a, g dbSNP:751392690
499 499 a, g dbSNP:759139812
501 501 c, t dbSNP:766927852
502 502 g, t dbSNP:267606938
509 509 a, g dbSNP:368756677
531 531 c, t dbSNP:755698784
532 532 a, g dbSNP:777354361
550 550 a, g dbSNP:750815139
553 553 c, g dbSNP:758705968
567 567 c, g, t dbSNP:780597558
570 570 c, t dbSNP:768820696
576 576 g, t dbSNP:781113804
589 589 c, g dbSNP:748213138
592 592 a, c, g dbSNP:144604949
601 601 a, c, t dbSNP:565152013
602 602 a, g dbSNP:147845975
603 603 c, g dbSNP:759361135
622 622 c, t dbSNP:767102971
629 629 c, g dbSNP:752170333
630 630 c, t dbSNP:376531662
631 631 a, c dbSNP:201131767
643 643 c, t dbSNP:141399719
646 646 a, g dbSNP:151019488
648 648 a, g dbSNP:368265235
650 650 -, t dbSNP:768282589
708 708 c, t dbSNP:758829356
717 717 g, t dbSNP:780250994
718 718 a, g dbSNP:752161030
726 726 a, g, t dbSNP:755465648
735 735 a, t dbSNP:200661557
740 740 c, t dbSNP:750529031
760 760 a, g dbSNP:769934912
761 761 c, g, t dbSNP:778196214
762 762 a, g dbSNP:770886339
766 766 c, g dbSNP:773995220
771 771 c, t dbSNP:202034256
774 774 c, t dbSNP:771933821
775 775 c, t dbSNP:775429341
776 776 a, g dbSNP:760238687
781 781 c, t dbSNP:763591084
782 782 c, g, t dbSNP:572895007
795 795 c, t dbSNP:764899090
825 825 a, c, t dbSNP:541907484
835 835 a, g dbSNP:767925776
848 848 a, g dbSNP:753240948
866 866 c, t dbSNP:200145429
876 876 a, g dbSNP:777966209
879 879 a, g dbSNP:749570505
882 882 c, t dbSNP:374859758
894 894 c, t dbSNP:138512618
896 896 c, t dbSNP:140780685
903 903 c, g dbSNP:199977411
905 905 c, t dbSNP:771889434
906 906 a, g dbSNP:369055053
909 909 c, t dbSNP:757895185
914 914 c, g, t dbSNP:201467137
915 915 c, t dbSNP:776144330
918 918 c, t dbSNP:761277113
930 930 g, t dbSNP:764804506
931 931 c, t dbSNP:772866221
942 942 c, g dbSNP:150112501
963 963 c, t dbSNP:767917111
978 978 a, g dbSNP:138553326
1001 1001 g, t dbSNP:750473319
1002 1002 g, t dbSNP:753292297
1005 1005 c, t dbSNP:140224111
1007 1007 a, g dbSNP:145915456
1010 1010 a, c dbSNP:754001678
1022 1022 a, g dbSNP:757292942
1029 1029 a, g dbSNP:779015042
1032 1032 a, t dbSNP:746100755
1041 1041 c, t dbSNP:758169742
1053 1053 a, g dbSNP:779802119
1056 1056 c, t dbSNP:746758163
1072 1072 g, t dbSNP:768615485
1080 1080 c, t dbSNP:201021364
1088 1088 a, g dbSNP:747673653
1095 1095 c, t dbSNP:561440517
1096 1096 a, g dbSNP:772803719
1103 1103 a, g dbSNP:762632055
1111 1111 c, g dbSNP:758604713
1117 1117 a, g dbSNP:373016029
1122 1122 a, g dbSNP:776018911
1123 1123 c, g dbSNP:780162130
1125 1125 a, g dbSNP:761080494
1131 1131 c, t dbSNP:138488258
1134 1134 c, t dbSNP:146222349
1138 1138 c, t dbSNP:149633208
1144 1144 g, t dbSNP:765330955
1151 1151 c, t dbSNP:750660703
1152 1152 a, g dbSNP:758670020
1162 1162 a, g dbSNP:780213686
1169 1169 a, g dbSNP:751365113
1176 1176 a, g dbSNP:754713600
1192 1192 a, g dbSNP:370143029
1196 1196 a, g dbSNP:748108713
1204 1204 c, t dbSNP:373354872
1205 1205 g, t dbSNP:529355400
1218 1218 a, g dbSNP:200054483
1226 1226 c, g dbSNP:770737506
1227 1227 c, g dbSNP:774080309
1236 1236 c, t dbSNP:761133347
1237 1237 a, g dbSNP:769128065
1246 1246 c, g dbSNP:144339806
1249 1249 c, t dbSNP:762362258
1254 1254 c, g dbSNP:755900273
1255 1255 c, t dbSNP:534701211
1258 1258 -, g dbSNP:774046054
1293 1293 a, g dbSNP:769050733
1315 1315 c, g dbSNP:750548247
1329 1329 a, g dbSNP:762878527
1332 1332 a, g dbSNP:766605438
1344 1344 a, g dbSNP:751770350
1354 1354 a, t dbSNP:754838278
1355 1355 a, g dbSNP:780930808
1368 1368 c, t dbSNP:752624152
1378 1378 a, t dbSNP:777603105
1383 1383 c, t dbSNP:777530209
1394 1394 a, c dbSNP:748834473
1396 1396 a, t dbSNP:756767503
1401 1401 g, t dbSNP:778764676
1407 1407 c, t dbSNP:745485872
1429 1429 a, g dbSNP:769193664
1434 1434 c, t dbSNP:777075890
1438 1438 c, t dbSNP:377342640
1439 1439 a, g dbSNP:770342233
1453 1453 g, t dbSNP:369447724
1454 1454 a, g dbSNP:763153521
1458 1458 a, g dbSNP:374326474
1467 1467 a, g dbSNP:148348306
1476 1476 c, t dbSNP:774592444
1483 1483 g, t dbSNP:759729815
1492 1492 a, g dbSNP:767674134
1499 1499 a, g dbSNP:200222464
1506 1506 a, c, g dbSNP:141493326
1509 1509 c, t dbSNP:753703262
1529 1529 a, g dbSNP:756892474
1536 1536 a, t dbSNP:778545811
1541 1541 a, g dbSNP:745323862
1543 1543 a, g dbSNP:758156720
1547 1547 a, g dbSNP:779506684
1554 1554 a, c dbSNP:748562555
1566 1566 g, t dbSNP:770046269
1567 1567 a, g dbSNP:749168775
1579 1579 a, g dbSNP:773838560
1580 1580 a, g dbSNP:749767366
1581 1581 a, g dbSNP:771044295
1588 1588 c, g dbSNP:373946288
1591 1591 a, g dbSNP:759570204
1600 1600 c, g dbSNP:767783621
1605 1605 -, cctttta dbSNP:747806749
1618 1618 a, g dbSNP:775515661
1623 1623 a, g dbSNP:760576538
1625 1625 c, g dbSNP:763792118
1627 1627 a, g dbSNP:377553463
1638 1638 a, g dbSNP:757283913
1642 1642 c, t dbSNP:201132164
1648 1648 g, t dbSNP:749959908
1650 1650 a, t dbSNP:757927785
1654 1654 a, g dbSNP:779817145
1656 1656 c, t dbSNP:147477305
1657 1657 a, g dbSNP:756545344
1659 1659 a, g dbSNP:117294206
1671 1671 a, c, t dbSNP:137975172
1672 1672 a, g dbSNP:370390664
1675 1675 c, t dbSNP:745958515
1680 1680 c, t dbSNP:374262682
1686 1686 a, g dbSNP:775848242
1691 1691 a, g dbSNP:760776715
1695 1695 c, t dbSNP:768875523
1706 1706 c, t dbSNP:776599018
1720 1720 c, t dbSNP:761636189
1721 1721 a, g dbSNP:376060350
1727 1727 c, g dbSNP:750375166
1728 1728 c, t dbSNP:762593464
1745 1745 c, g dbSNP:145358369
1752 1752 a, g dbSNP:751277921
1759 1759 c, t dbSNP:202225648
1770 1770 a, g dbSNP:754605931
1783 1783 a, g dbSNP:202145000
1792 1792 c, g dbSNP:754204252
1795 1795 c, g dbSNP:147237491
1802 1802 a, g dbSNP:779452040
1804 1804 c, t dbSNP:746369671
1810 1810 g, t dbSNP:772232968
1813 1813 a, g dbSNP:780020258
1815 1815 -, g dbSNP:772846653
1818 1818 a, g dbSNP:747071043
1820 1820 c, t dbSNP:768767735
1821 1821 a, g dbSNP:535568386
1839 1839 c, g dbSNP:139199750
1840 1840 c, t dbSNP:761761105
1841 1841 c, g dbSNP:769711015
1853 1853 c, t dbSNP:773326652
1855 1855 a, c dbSNP:762781777
1859 1859 c, g dbSNP:766287359
1861 1861 a, g dbSNP:555465685
1864 1864 c, g dbSNP:41272415
1870 1870 c, t dbSNP:759016944
1875 1875 c, t dbSNP:4735258
1876 1876 a, g dbSNP:752331175
1877 1877 c, t dbSNP:757684185
1878 1878 a, g dbSNP:765555188
1885 1885 a, g, t dbSNP:750976092
1888 1888 a, c dbSNP:192535454
1890 1890 g, t dbSNP:149521176
1898 1898 a, t dbSNP:540479716
1904 1904 a, g dbSNP:144036151
1910 1910 c, t dbSNP:148691545
1921 1921 a, g dbSNP:542596810
1932 1932 a, g dbSNP:144473673
1996 1996 -, a dbSNP:760027289
2019 2019 c, t dbSNP:577643189
2130 2130 a, g dbSNP:769186837
2140 2140 a, g dbSNP:531689009
2207 2207 c, g dbSNP:551728387
2212 2212 c, t dbSNP:185126352
2232 2232 c, t dbSNP:527981638
2259 2259 c, t dbSNP:548043412
2291 2291 c, t dbSNP:566488276
2297 2297 a, t dbSNP:535475031
2330 2330 g, t dbSNP:41272417
2348 2348 a, c, g dbSNP:199846257
2405 2405 c, t dbSNP:78884124
2431 2431 a, g dbSNP:537935933
2437 2437 c, t dbSNP:557676479
2449 2449 a, g dbSNP:190420045
2460 2460 a, g dbSNP:545692596
2468 2468 a, g dbSNP:192629673
2470 2470 c, g dbSNP:911
2478 2478 a, g dbSNP:147461233
2484 2484 c, g dbSNP:762341289
2494 2494 a, g dbSNP:185015320
2505 2505 -, g dbSNP:139623857
2542 2542 a, g dbSNP:562533870
2550 2550 a, g dbSNP:554502999
2566 2566 c, t dbSNP:545440707
2646 2646 a, c dbSNP:188727327
2651 2651 a, g dbSNP:765693471
2697 2697 c, t dbSNP:750465585
2698 2698 a, g dbSNP:527854224
2713 2713 g, t dbSNP:572912702
2725 2725 c, t dbSNP:547657737
2737 2737 -, ctt dbSNP:756226872
2749 2749 a, t dbSNP:7461396
2769 2769 a, g dbSNP:180752222
2796 2796 a, g dbSNP:75265995
2841 2841 -, g dbSNP:35866235
2846 2846 a, g dbSNP:185360919
2868 2868 c, g dbSNP:762919416
2930 2930 a, c dbSNP:568829851
2939 2939 a, g dbSNP:540442395
2952 2952 c, t dbSNP:537546709
2953 2953 a, g dbSNP:551427862
2966 2966 c, t dbSNP:766520277
3042 3042 -, g dbSNP:35793146
3067 3067 a, c dbSNP:571367515
3078 3078 a, c dbSNP:751718373
3089 3089 a, g dbSNP:534020211
3163 3163 a, c, g dbSNP:774244422
3172 3172 a, g dbSNP:553548239
3180 3180 g, t dbSNP:573640783
3189 3189 c, t dbSNP:561592504
3245 3245 a, c dbSNP:753665809
3248 3248 a, g dbSNP:757140568
3258 3258 a, c dbSNP:201779185
3281 3281 a, g dbSNP:748740342
3326 3326 a, t dbSNP:189435075
3335 3335 a, t dbSNP:576359274
3350 3350 c, t dbSNP:745862328
3356 3356 a, g dbSNP:545190275
3377 3377 c, t dbSNP:771482216
3388 3388 c, t dbSNP:565409416
3390 3390 g, t dbSNP:779668197
3403 3403 a, c dbSNP:111728711
3448 3448 a, g dbSNP:186669527
3487 3487 -, t dbSNP:778564057
3487 3487 -, g dbSNP:145384326
3488 3488 g, t dbSNP:377214447
3489 3489 g, t dbSNP:192025344
3500 3500 -, t dbSNP:60316663
3503 3503 a, g dbSNP:558897089
3529 3529 a, g dbSNP:777095381
3559 3559 a, g dbSNP:566314054
3575 3575 c, g dbSNP:116788695
3601 3601 c, t dbSNP:568255963
3627 3627 -, c dbSNP:753816030
3638 3638 c, g dbSNP:535028389
3642 3642 c, g dbSNP:773560152
3644 3644 a, g dbSNP:531302765
3646 3646 a, t dbSNP:77734416
3669 3669 c, g dbSNP:571368323
3676 3676 a, g dbSNP:533642903
3685 3685 a, g dbSNP:537145163
3697 3697 a, g dbSNP:767466121
3708 3708 a, g dbSNP:553341714
3745 3745 g, t dbSNP:567078023
3761 3761 a, t dbSNP:139839619
3789 3789 c, t dbSNP:751645556
3914 3914 -, a dbSNP:368109978
3925 3925 a, g dbSNP:556007957
3934 3934 c, t dbSNP:115434133
4054 4054 g, t dbSNP:759715556
4069 4069 a, t dbSNP:767751976
4094 4094 c, t dbSNP:183503324
4096 4096 a, t dbSNP:367694582
4102 4102 c, t dbSNP:145337691
4139 4139 -, a dbSNP:539401507
4152 4152 g, t dbSNP:754099555
4175 4175 a, t dbSNP:186410170
4192 4192 g, t dbSNP:190113849
4224 4224 a, t dbSNP:557560034
4230 4230 -, c dbSNP:745781350

Target ORF information:

RefSeq Version NM_001161780
Organism Homo sapiens (human)
Definition Homo sapiens pyruvate dehyrogenase phosphatase catalytic subunit 1 (PDP1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001161780

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGTGTGTGT GTCCCGGGCC CAGACGAATT GGAATCCCAG TCAGAAGTTC CAGCCTGCCA 
CTGTTCTCTG ATGCCATGCC AGCACCAACT CAACTGTTTT TTCCTCTCAT CCGTAACTGT
GAACTGAGCA GGATCTATGG CACTGCATGT TACTGCCACC ACAAACATCT CTGTTGTTCC
TCATCGTACA TTCCTCAGAG TCGACTGAGA TACACACCTC ATCCAGCATA TGCTACCTTT
TGCAGGCCAA AGGAGAACTG GTGGCAGTAC ACCCAAGGAA GGAGATATGC TTCCACACCA
CAGAAATTTT ACCTCACACC TCCACAAGTC AATAGCATCC TTAAAGCTAA TGAATACAGT
TTCAAAGTGC CAGAATTTGA CGGCAAAAAT GTCAGTTCTA TCCTTGGATT TGACAGCAAT
CAGCTGCCTG CAAATGCACC CATTGAGGAC CGGAGAAGTG CAGCAACCTG CTTGCAGACC
AGAGGGATGC TTTTGGGGGT TTTTGATGGC CATGCAGGTT GTGCTTGTTC CCAGGCAGTC
AGTGAAAGAC TCTTTTATTA TATTGCTGTC TCTTTGTTAC CCCATGAGAC TTTGCTAGAG
ATTGAAAATG CAGTGGAGAG CGGCCGGGCA CTGCTACCCA TTCTCCAGTG GCACAAGCAC
CCCAATGATT ACTTTAGTAA GGAGGCATCC AAATTGTACT TTAACAGCTT GAGGACTTAC
TGGCAAGAGC TTATAGACCT CAACACTGGT GAGTCGACTG ATATTGATGT TAAGGAGGCT
CTAATTAATG CCTTCAAGAG GCTTGATAAT GACATCTCCT TGGAGGCGCA AGTTGGTGAT
CCTAATTCTT TTCTCAACTA CCTGGTGCTT CGAGTGGCAT TTTCTGGAGC CACTGCTTGT
GTGGCCCATG TGGATGGTGT TGACCTTCAT GTGGCCAATA CTGGCGATAG CAGAGCCATG
CTGGGTGTGC AGGAAGAGGA CGGCTCATGG TCAGCAGTCA CGCTGTCTAA TGACCACAAT
GCTCAAAATG AAAGAGAACT AGAACGGCTG AAATTGGAAC ATCCAAAGAG TGAGGCCAAG
AGTGTCGTGA AACAGGATCG GCTGCTTGGC TTGCTGATGC CATTTAGGGC ATTTGGAGAT
GTAAAGTTCA AATGGAGCAT TGACCTTCAA AAGAGAGTGA TAGAATCTGG CCCAGACCAG
TTGAATGACA ATGAATATAC CAAGTTTATT CCTCCTAATT ATCACACACC TCCTTATCTC
ACTGCTGAGC CAGAGGTAAC TTACCACCGA TTAAGGCCAC AGGATAAGTT TCTGGTGTTG
GCTACTGATG GGTTGTGGGA GACTATGCAT AGGCAGGATG TGGTTAGGAT TGTGGGTGAG
TACCTAACTG GCATGCATCA CCAACAGCCA ATAGCTGTTG GTGGCTACAA GGTGACTCTG
GGACAGATGC ATGGCCTTTT AACAGAAAGG AGAACCAAAA TGTCCTCGGT ATTTGAGGAT
CAGAACGCAG CAACCCATCT CATTCGCCAC GCTGTGGGCA ACAACGAGTT TGGGACTGTT
GATCATGAGC GCCTCTCTAA AATGCTTAGT CTTCCTGAAG AGCTTGCTCG AATGTACAGA
GATGACATTA CAATCATTGT AGTTCAGTTC AATTCTCATG TTGTAGGGGC GTATCAAAAC
CAAGAATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu17459
Accession Version NM_001161779.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1689bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product pyruvate dehyrogenase phosphatase catalytic subunit 1 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA769567.1, BC098343.1, AK126862.1 and BX099681.1. Summary: Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009]. Transcript Variant: This variant (2) is the longest transcript. This variant and variant 3 encode the same isoform (2). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: DA769567.1, DA233418.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
ATGTGTGTGT GTCCCGGGCC CAGACGAATT GGAATCCCAG TCAGAAGTTC CAGCCTGCCA 
CTGTTCTCTG ATGCCATGCC AGCACCAACT CAACTGTTTT TTCCTCTCAT CCGTAACTGT
GAACTGAGCA GGATCTATGG CACTGCATGT TACTGCCACC ACAAACATCT CTGTTGTTCC
TCATCGTACA TTCCTCAGAG TCGACTGAGA TACACACCTC ATCCAGCATA TGCTACCTTT
TGCAGGCCAA AGGAGAACTG GTGGCAGTAC ACCCAAGGAA GGAGATATGC TTCCACACCA
CAGAAATTTT ACCTCACACC TCCACAAGTC AATAGCATCC TTAAAGCTAA TGAATACAGT
TTCAAAGTGC CAGAATTTGA CGGCAAAAAT GTCAGTTCTA TCCTTGGATT TGACAGCAAT
CAGCTGCCTG CAAATGCACC CATTGAGGAC CGGAGAAGTG CAGCAACCTG CTTGCAGACC
AGAGGGATGC TTTTGGGGGT TTTTGATGGC CATGCAGGTT GTGCTTGTTC CCAGGCAGTC
AGTGAAAGAC TCTTTTATTA TATTGCTGTC TCTTTGTTAC CCCATGAGAC TTTGCTAGAG
ATTGAAAATG CAGTGGAGAG CGGCCGGGCA CTGCTACCCA TTCTCCAGTG GCACAAGCAC
CCCAATGATT ACTTTAGTAA GGAGGCATCC AAATTGTACT TTAACAGCTT GAGGACTTAC
TGGCAAGAGC TTATAGACCT CAACACTGGT GAGTCGACTG ATATTGATGT TAAGGAGGCT
CTAATTAATG CCTTCAAGAG GCTTGATAAT GACATCTCCT TGGAGGCGCA AGTTGGTGAT
CCTAATTCTT TTCTCAACTA CCTGGTGCTT CGAGTGGCAT TTTCTGGAGC CACTGCTTGT
GTGGCCCATG TGGATGGTGT TGACCTTCAT GTGGCCAATA CTGGCGATAG CAGAGCCATG
CTGGGTGTGC AGGAAGAGGA CGGCTCATGG TCAGCAGTCA CGCTGTCTAA TGACCACAAT
GCTCAAAATG AAAGAGAACT AGAACGGCTG AAATTGGAAC ATCCAAAGAG TGAGGCCAAG
AGTGTCGTGA AACAGGATCG GCTGCTTGGC TTGCTGATGC CATTTAGGGC ATTTGGAGAT
GTAAAGTTCA AATGGAGCAT TGACCTTCAA AAGAGAGTGA TAGAATCTGG CCCAGACCAG
TTGAATGACA ATGAATATAC CAAGTTTATT CCTCCTAATT ATCACACACC TCCTTATCTC
ACTGCTGAGC CAGAGGTAAC TTACCACCGA TTAAGGCCAC AGGATAAGTT TCTGGTGTTG
GCTACTGATG GGTTGTGGGA GACTATGCAT AGGCAGGATG TGGTTAGGAT TGTGGGTGAG
TACCTAACTG GCATGCATCA CCAACAGCCA ATAGCTGTTG GTGGCTACAA GGTGACTCTG
GGACAGATGC ATGGCCTTTT AACAGAAAGG AGAACCAAAA TGTCCTCGGT ATTTGAGGAT
CAGAACGCAG CAACCCATCT CATTCGCCAC GCTGTGGGCA ACAACGAGTT TGGGACTGTT
GATCATGAGC GCCTCTCTAA AATGCTTAGT CTTCCTGAAG AGCTTGCTCG AATGTACAGA
GATGACATTA CAATCATTGT AGTTCAGTTC AATTCTCATG TTGTAGGGGC GTATCAAAAC
CAAGAATAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001155251.1
CDS277..1965
Misc Feature(1)676..1926(+)
Misc Feature(2)709..1899(+)
Exon (1)1..272
Gene:PDP1
Gene Synonym:
Exon (2)273..307
Gene:PDP1
Gene Synonym:
Exon (3)308..4360
Gene:PDP1
Gene Synonym:
Translation
Position Chain Variation Link
8 8 a, g dbSNP:769982392
14 14 -, g dbSNP:766339112
14 14 c, t dbSNP:777681394
15 15 a, g dbSNP:749570657
17 17 c, g, t dbSNP:771299570
18 18 g, t dbSNP:759405446
19 19 a, g dbSNP:771703282
20 20 -, ga dbSNP:752725428
26 26 c, t dbSNP:775552151
28 28 a, c, t dbSNP:570396595
32 32 c, g dbSNP:753371996
35 35 c, t dbSNP:761273137
36 36 a, g dbSNP:764874879
38 38 a, g dbSNP:750022171
40 40 c, g dbSNP:755429761
42 42 c, t dbSNP:202016823
48 48 a, g dbSNP:781404802
50 50 c, g, t dbSNP:527903830
51 51 a, c, t dbSNP:756556074
54 54 c, t dbSNP:749406937
56 56 a, t dbSNP:771064281
57 57 a, g dbSNP:779287937
59 59 a, g dbSNP:746071530
66 66 a, g dbSNP:771944772
69 69 c, g dbSNP:775128777
71 71 a, g dbSNP:760474141
83 83 c, t dbSNP:768510527
100 100 g, t dbSNP:776484586
103 103 a, g dbSNP:761326355
104 104 a, g dbSNP:764715116
105 105 a, g dbSNP:532831481
107 107 c, g dbSNP:762480054
111 111 a, c dbSNP:372548037
112 112 a, g dbSNP:753025018
127 127 a, g dbSNP:756461276
133 133 a, g dbSNP:764697879
138 138 a, c, g dbSNP:754334796
143 143 c, t dbSNP:551438751
150 150 c, t dbSNP:779128526
158 158 c, t dbSNP:746152694
159 159 g, t dbSNP:571183462
161 161 a, g dbSNP:780286356
165 165 c, g dbSNP:746785154
167 167 c, t dbSNP:533654904
168 168 c, t dbSNP:549284239
172 172 c, t dbSNP:776609635
173 173 a, g dbSNP:748076227
181 181 a, c dbSNP:769332830
181 181 -, c dbSNP:764235380
216 216 c, g dbSNP:550050833
228 228 a, g dbSNP:186315844
229 229 a, c dbSNP:567368232
240 240 g, t dbSNP:536079235
277 277 -, tg dbSNP:756648979
278 278 -, tg dbSNP:746354729
278 278 c, t dbSNP:755168595
285 285 a, g dbSNP:781341112
286 286 c, t dbSNP:752519178
295 295 c, t dbSNP:755840386
299 299 a, g dbSNP:777581092
302 302 a, g dbSNP:749231431
310 310 a, g dbSNP:368896704
313 313 c, t dbSNP:745378971
325 325 c, t dbSNP:76597597
327 327 c, t dbSNP:771654817
328 328 a, t dbSNP:779914919
329 329 g, t dbSNP:746656680
337 337 -, t dbSNP:748745930
339 339 c, g dbSNP:373914341
342 342 a, c dbSNP:767109728
347 347 a, g dbSNP:763177277
348 348 a, t dbSNP:771499042
352 352 a, g dbSNP:774772187
356 356 c, t dbSNP:775877089
364 364 a, g dbSNP:759621538
365 365 c, g dbSNP:376864107
367 367 c, t dbSNP:775755715
369 369 a, c dbSNP:760854097
371 371 a, t dbSNP:763841975
373 373 c, t dbSNP:753700131
375 375 c, t dbSNP:756937580
376 376 c, t dbSNP:371323550
383 383 c, t dbSNP:765234818
388 388 c, t dbSNP:750372945
389 389 a, g dbSNP:758052799
398 398 a, t dbSNP:760929995
401 401 c, t dbSNP:746711864
407 407 a, g dbSNP:754684543
413 413 a, g dbSNP:780665993
417 417 c, t dbSNP:749664764
419 419 c, g dbSNP:771139058
424 424 c, t dbSNP:774892672
425 425 a, g dbSNP:746369657
435 435 c, t dbSNP:772178775
438 438 c, t dbSNP:758947272
442 442 c, t dbSNP:201452113
443 443 a, g, t dbSNP:764383471
462 462 a, c, g, t dbSNP:761727112
475 475 a, g dbSNP:758390717
478 478 c, t dbSNP:766372826
479 479 a, g dbSNP:201081450
481 481 c, g dbSNP:754376963
482 482 c, t dbSNP:780907656
496 496 c, t dbSNP:747738989
505 505 c, t dbSNP:140713866
534 534 c, t dbSNP:779217265
546 546 c, t dbSNP:375147234
547 547 a, g dbSNP:569067471
552 552 a, c, g dbSNP:775911139
553 553 a, g dbSNP:374758737
563 563 a, g dbSNP:776979550
565 565 g, t dbSNP:761913953
566 566 c, t dbSNP:769765131
577 577 a, c dbSNP:773166625
590 590 c, t dbSNP:79439881
608 608 a, g dbSNP:762798871
612 612 c, t dbSNP:144544236
622 622 a, g dbSNP:751392690
625 625 a, g dbSNP:759139812
627 627 c, t dbSNP:766927852
628 628 g, t dbSNP:267606938
635 635 a, g dbSNP:368756677
657 657 c, t dbSNP:755698784
658 658 a, g dbSNP:777354361
676 676 a, g dbSNP:750815139
679 679 c, g dbSNP:758705968
693 693 c, g, t dbSNP:780597558
696 696 c, t dbSNP:768820696
702 702 g, t dbSNP:781113804
715 715 c, g dbSNP:748213138
718 718 a, c, g dbSNP:144604949
727 727 a, c, t dbSNP:565152013
728 728 a, g dbSNP:147845975
729 729 c, g dbSNP:759361135
748 748 c, t dbSNP:767102971
755 755 c, g dbSNP:752170333
756 756 c, t dbSNP:376531662
757 757 a, c dbSNP:201131767
769 769 c, t dbSNP:141399719
772 772 a, g dbSNP:151019488
774 774 a, g dbSNP:368265235
776 776 -, t dbSNP:768282589
834 834 c, t dbSNP:758829356
843 843 g, t dbSNP:780250994
844 844 a, g dbSNP:752161030
852 852 a, g, t dbSNP:755465648
861 861 a, t dbSNP:200661557
866 866 c, t dbSNP:750529031
886 886 a, g dbSNP:769934912
887 887 c, g, t dbSNP:778196214
888 888 a, g dbSNP:770886339
892 892 c, g dbSNP:773995220
897 897 c, t dbSNP:202034256
900 900 c, t dbSNP:771933821
901 901 c, t dbSNP:775429341
902 902 a, g dbSNP:760238687
907 907 c, t dbSNP:763591084
908 908 c, g, t dbSNP:572895007
921 921 c, t dbSNP:764899090
951 951 a, c, t dbSNP:541907484
961 961 a, g dbSNP:767925776
974 974 a, g dbSNP:753240948
992 992 c, t dbSNP:200145429
1002 1002 a, g dbSNP:777966209
1005 1005 a, g dbSNP:749570505
1008 1008 c, t dbSNP:374859758
1020 1020 c, t dbSNP:138512618
1022 1022 c, t dbSNP:140780685
1029 1029 c, g dbSNP:199977411
1031 1031 c, t dbSNP:771889434
1032 1032 a, g dbSNP:369055053
1035 1035 c, t dbSNP:757895185
1040 1040 c, g, t dbSNP:201467137
1041 1041 c, t dbSNP:776144330
1044 1044 c, t dbSNP:761277113
1056 1056 g, t dbSNP:764804506
1057 1057 c, t dbSNP:772866221
1068 1068 c, g dbSNP:150112501
1089 1089 c, t dbSNP:767917111
1104 1104 a, g dbSNP:138553326
1127 1127 g, t dbSNP:750473319
1128 1128 g, t dbSNP:753292297
1131 1131 c, t dbSNP:140224111
1133 1133 a, g dbSNP:145915456
1136 1136 a, c dbSNP:754001678
1148 1148 a, g dbSNP:757292942
1155 1155 a, g dbSNP:779015042
1158 1158 a, t dbSNP:746100755
1167 1167 c, t dbSNP:758169742
1179 1179 a, g dbSNP:779802119
1182 1182 c, t dbSNP:746758163
1198 1198 g, t dbSNP:768615485
1206 1206 c, t dbSNP:201021364
1214 1214 a, g dbSNP:747673653
1221 1221 c, t dbSNP:561440517
1222 1222 a, g dbSNP:772803719
1229 1229 a, g dbSNP:762632055
1237 1237 c, g dbSNP:758604713
1243 1243 a, g dbSNP:373016029
1248 1248 a, g dbSNP:776018911
1249 1249 c, g dbSNP:780162130
1251 1251 a, g dbSNP:761080494
1257 1257 c, t dbSNP:138488258
1260 1260 c, t dbSNP:146222349
1264 1264 c, t dbSNP:149633208
1270 1270 g, t dbSNP:765330955
1277 1277 c, t dbSNP:750660703
1278 1278 a, g dbSNP:758670020
1288 1288 a, g dbSNP:780213686
1295 1295 a, g dbSNP:751365113
1302 1302 a, g dbSNP:754713600
1318 1318 a, g dbSNP:370143029
1322 1322 a, g dbSNP:748108713
1330 1330 c, t dbSNP:373354872
1331 1331 g, t dbSNP:529355400
1344 1344 a, g dbSNP:200054483
1352 1352 c, g dbSNP:770737506
1353 1353 c, g dbSNP:774080309
1362 1362 c, t dbSNP:761133347
1363 1363 a, g dbSNP:769128065
1372 1372 c, g dbSNP:144339806
1375 1375 c, t dbSNP:762362258
1380 1380 c, g dbSNP:755900273
1381 1381 c, t dbSNP:534701211
1384 1384 -, g dbSNP:774046054
1419 1419 a, g dbSNP:769050733
1441 1441 c, g dbSNP:750548247
1455 1455 a, g dbSNP:762878527
1458 1458 a, g dbSNP:766605438
1470 1470 a, g dbSNP:751770350
1480 1480 a, t dbSNP:754838278
1481 1481 a, g dbSNP:780930808
1494 1494 c, t dbSNP:752624152
1504 1504 a, t dbSNP:777603105
1509 1509 c, t dbSNP:777530209
1520 1520 a, c dbSNP:748834473
1522 1522 a, t dbSNP:756767503
1527 1527 g, t dbSNP:778764676
1533 1533 c, t dbSNP:745485872
1555 1555 a, g dbSNP:769193664
1560 1560 c, t dbSNP:777075890
1564 1564 c, t dbSNP:377342640
1565 1565 a, g dbSNP:770342233
1579 1579 g, t dbSNP:369447724
1580 1580 a, g dbSNP:763153521
1584 1584 a, g dbSNP:374326474
1593 1593 a, g dbSNP:148348306
1602 1602 c, t dbSNP:774592444
1609 1609 g, t dbSNP:759729815
1618 1618 a, g dbSNP:767674134
1625 1625 a, g dbSNP:200222464
1632 1632 a, c, g dbSNP:141493326
1635 1635 c, t dbSNP:753703262
1655 1655 a, g dbSNP:756892474
1662 1662 a, t dbSNP:778545811
1667 1667 a, g dbSNP:745323862
1669 1669 a, g dbSNP:758156720
1673 1673 a, g dbSNP:779506684
1680 1680 a, c dbSNP:748562555
1692 1692 g, t dbSNP:770046269
1693 1693 a, g dbSNP:749168775
1705 1705 a, g dbSNP:773838560
1706 1706 a, g dbSNP:749767366
1707 1707 a, g dbSNP:771044295
1714 1714 c, g dbSNP:373946288
1717 1717 a, g dbSNP:759570204
1726 1726 c, g dbSNP:767783621
1731 1731 -, cctttta dbSNP:747806749
1744 1744 a, g dbSNP:775515661
1749 1749 a, g dbSNP:760576538
1751 1751 c, g dbSNP:763792118
1753 1753 a, g dbSNP:377553463
1764 1764 a, g dbSNP:757283913
1768 1768 c, t dbSNP:201132164
1774 1774 g, t dbSNP:749959908
1776 1776 a, t dbSNP:757927785
1780 1780 a, g dbSNP:779817145
1782 1782 c, t dbSNP:147477305
1783 1783 a, g dbSNP:756545344
1785 1785 a, g dbSNP:117294206
1797 1797 a, c, t dbSNP:137975172
1798 1798 a, g dbSNP:370390664
1801 1801 c, t dbSNP:745958515
1806 1806 c, t dbSNP:374262682
1812 1812 a, g dbSNP:775848242
1817 1817 a, g dbSNP:760776715
1821 1821 c, t dbSNP:768875523
1832 1832 c, t dbSNP:776599018
1846 1846 c, t dbSNP:761636189
1847 1847 a, g dbSNP:376060350
1853 1853 c, g dbSNP:750375166
1854 1854 c, t dbSNP:762593464
1871 1871 c, g dbSNP:145358369
1878 1878 a, g dbSNP:751277921
1885 1885 c, t dbSNP:202225648
1896 1896 a, g dbSNP:754605931
1909 1909 a, g dbSNP:202145000
1918 1918 c, g dbSNP:754204252
1921 1921 c, g dbSNP:147237491
1928 1928 a, g dbSNP:779452040
1930 1930 c, t dbSNP:746369671
1936 1936 g, t dbSNP:772232968
1939 1939 a, g dbSNP:780020258
1941 1941 -, g dbSNP:772846653
1944 1944 a, g dbSNP:747071043
1946 1946 c, t dbSNP:768767735
1947 1947 a, g dbSNP:535568386
1965 1965 c, g dbSNP:139199750
1966 1966 c, t dbSNP:761761105
1967 1967 c, g dbSNP:769711015
1979 1979 c, t dbSNP:773326652
1981 1981 a, c dbSNP:762781777
1985 1985 c, g dbSNP:766287359
1987 1987 a, g dbSNP:555465685
1990 1990 c, g dbSNP:41272415
1996 1996 c, t dbSNP:759016944
2001 2001 c, t dbSNP:4735258
2002 2002 a, g dbSNP:752331175
2003 2003 c, t dbSNP:757684185
2004 2004 a, g dbSNP:765555188
2011 2011 a, g, t dbSNP:750976092
2014 2014 a, c dbSNP:192535454
2016 2016 g, t dbSNP:149521176
2024 2024 a, t dbSNP:540479716
2030 2030 a, g dbSNP:144036151
2036 2036 c, t dbSNP:148691545
2047 2047 a, g dbSNP:542596810
2058 2058 a, g dbSNP:144473673
2122 2122 -, a dbSNP:760027289
2145 2145 c, t dbSNP:577643189
2256 2256 a, g dbSNP:769186837
2266 2266 a, g dbSNP:531689009
2333 2333 c, g dbSNP:551728387
2338 2338 c, t dbSNP:185126352
2358 2358 c, t dbSNP:527981638
2385 2385 c, t dbSNP:548043412
2417 2417 c, t dbSNP:566488276
2423 2423 a, t dbSNP:535475031
2456 2456 g, t dbSNP:41272417
2474 2474 a, c, g dbSNP:199846257
2531 2531 c, t dbSNP:78884124
2557 2557 a, g dbSNP:537935933
2563 2563 c, t dbSNP:557676479
2575 2575 a, g dbSNP:190420045
2586 2586 a, g dbSNP:545692596
2594 2594 a, g dbSNP:192629673
2596 2596 c, g dbSNP:911
2604 2604 a, g dbSNP:147461233
2610 2610 c, g dbSNP:762341289
2620 2620 a, g dbSNP:185015320
2631 2631 -, g dbSNP:139623857
2668 2668 a, g dbSNP:562533870
2676 2676 a, g dbSNP:554502999
2692 2692 c, t dbSNP:545440707
2772 2772 a, c dbSNP:188727327
2777 2777 a, g dbSNP:765693471
2823 2823 c, t dbSNP:750465585
2824 2824 a, g dbSNP:527854224
2839 2839 g, t dbSNP:572912702
2851 2851 c, t dbSNP:547657737
2863 2863 -, ctt dbSNP:756226872
2875 2875 a, t dbSNP:7461396
2895 2895 a, g dbSNP:180752222
2922 2922 a, g dbSNP:75265995
2967 2967 -, g dbSNP:35866235
2972 2972 a, g dbSNP:185360919
2994 2994 c, g dbSNP:762919416
3056 3056 a, c dbSNP:568829851
3065 3065 a, g dbSNP:540442395
3078 3078 c, t dbSNP:537546709
3079 3079 a, g dbSNP:551427862
3092 3092 c, t dbSNP:766520277
3168 3168 -, g dbSNP:35793146
3193 3193 a, c dbSNP:571367515
3204 3204 a, c dbSNP:751718373
3215 3215 a, g dbSNP:534020211
3289 3289 a, c, g dbSNP:774244422
3298 3298 a, g dbSNP:553548239
3306 3306 g, t dbSNP:573640783
3315 3315 c, t dbSNP:561592504
3371 3371 a, c dbSNP:753665809
3374 3374 a, g dbSNP:757140568
3384 3384 a, c dbSNP:201779185
3407 3407 a, g dbSNP:748740342
3452