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SDHAF2 succinate dehydrogenase complex assembly factor 2 [Homo sapiens (human)]

Gene Symbol SDHAF2
Entrez Gene ID 54949
Full Name succinate dehydrogenase complex assembly factor 2
Synonyms C11orf79, PGL2, SDH5
General protein information
Preferred Names
succinate dehydrogenase assembly factor 2, mitochondrial
Names
succinate dehydrogenase assembly factor 2, mitochondrial
hSDH5
SDH assembly factor 2
succinate dehydrogenase subunit 5, mitochondrial
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11q12.2

Summary This gene encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Mutations in this gene are associated with paraganglioma.[provided by RefSeq, Jul 2010]. lac of sum
Disorder MIM:

613019

Disorder Html: Paragangliomas 2, 601650 (3)





The following SDHAF2 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SDHAF2 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu22591 NM_017841 Homo sapiens succinate dehydrogenase complex assembly factor 2 (SDHAF2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $99

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu22591
Accession Version NM_017841.2
Sequence Information ORF Nucleotide Sequence (Length: 501bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product succinate dehydrogenase assembly factor 2, mitochondrial
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK000494.1, AI039966.1 and AI660205.1. This sequence is a reference standard in the RefSeqGene project. On Jul 17, 2010 this sequence version replaced gi:8923449. Summary: This gene encodes a mitochondrial protein needed for the flavination of a succinate dehydrogenase complex subunit required for activity of the complex. Mutations in this gene are associated with paraganglioma.[provided by RefSeq, Jul 2010]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: AK000494.1, BC002331.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
ATGGCGGTGT CTACAGTGTT CTCGACTTCG TCGCTGATGC TTGCTCTGTC AAGGCACAGC 
CTATTGTCTC CTTTGCTCAG TGTGACATCA TTCAGACGCT TCTACAGAGG TGACAGCCCA
ACAGATTCCC AAAAGGACAT GATTGAAATC CCTTTGCCTC CATGGCAGGA GAGAACTGAT
GAATCCATAG AAACCAAAAG AGCCCGCCTG CTCTATGAGA GCAGAAAGAG GGGAATGTTG
GAAAACTGCA TTCTTCTTAG TCTTTTTGCT AAAGAACATC TGCAGCACAT GACAGAAAAG
CAGCTGAACC TCTATGACCG CCTGATTAAC GAGCCTAGTA ATGACTGGGA TATTTACTAC
TGGGCCACAG AAGCTAAACC AGCCCCAGAA ATATTTGAAA ATGAAGTCAT GGCCCTGCTG
AGAGACTTTG CTAAAAACAA AAACAAAGAG CAGAGACTGC GTGCCCCAGA TCTTGAGTAC
CTCTTTGAAA AGCCACGTTG A
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_060311.1
CDS23..523
Misc Feature(1)218..445(+)
Exon (1)1..58
Gene:SDHAF2
Gene Synonym:
Exon (2)59..282
Gene:SDHAF2
Gene Synonym:
Exon (3)283..392
Gene:SDHAF2
Gene Synonym:
Exon (4)393..1219
Gene:SDHAF2
Gene Synonym:
Translation
Position Chain Variation Link
2 2 c, t dbSNP:745713032
6 6 c, t dbSNP:370923256
12 12 a, g dbSNP:374676911
18 18 a, g dbSNP:549705433
22 22 a, c, g dbSNP:377266355
28 28 a, g, t dbSNP:747571875
29 29 g, t dbSNP:149277592
30 30 c, t dbSNP:760006057
33 33 c, g, t dbSNP:778449586
35 35 a, g dbSNP:775763888
37 37 a, g dbSNP:144511254
46 46 a, g dbSNP:764251580
48 48 c, t dbSNP:552102107
54 54 c, t dbSNP:148425779
67 67 c, t dbSNP:770012985
74 74 a, g dbSNP:200911550
85 85 a, g dbSNP:191513932
88 88 g, t dbSNP:766468929
98 98 c, g dbSNP:751530375
102 102 a, g, t dbSNP:759472787
115 115 c, g dbSNP:752477657
119 119 c, t dbSNP:144867876
120 120 a, g dbSNP:777442412
121 121 c, t dbSNP:753325226
122 122 c, t dbSNP:756917732
139 139 a, c dbSNP:780593356
144 144 c, t dbSNP:747508289
155 155 a, g dbSNP:368945911
161 161 a, g dbSNP:111402137
163 163 g, t dbSNP:748505431
167 167 -, gaa dbSNP:749431351
175 175 g, t dbSNP:769950627
178 178 a, g dbSNP:773466310
180 180 c, t dbSNP:562958122
185 185 c, t dbSNP:771133722
187 187 a, g dbSNP:774508076
188 188 a, c dbSNP:112578506
191 191 a, g dbSNP:759556749
193 193 g, t dbSNP:767436409
214 214 a, g dbSNP:113307092
216 216 c, t dbSNP:752462796
218 218 a, g dbSNP:371977724
220 220 a, g dbSNP:760482747
227 227 c, t dbSNP:532255760
228 228 a, g dbSNP:753474292
229 229 c, t dbSNP:756825771
238 238 c, t dbSNP:778397152
244 244 c, t dbSNP:749887667
252 252 c, g dbSNP:755511528
254 254 a, g dbSNP:113560320
257 257 a, g dbSNP:781702725
261 261 c, t dbSNP:376560419
277 277 g, t dbSNP:756492007
280 280 c, t dbSNP:777927167
284 284 c, t dbSNP:775356110
285 285 -, t dbSNP:766035180
287 287 c, t dbSNP:746968831
291 291 c, t dbSNP:373951663
295 295 a, g dbSNP:147928545
308 308 c, t dbSNP:755605816
310 310 c, t dbSNP:764919936
311 311 a, g dbSNP:201520416
316 316 a, g dbSNP:762441285
327 327 -, a dbSNP:753554501
331 331 c, t dbSNP:184314049
337 337 c, t dbSNP:750979204
341 341 c, t dbSNP:140191819
342 342 a, g dbSNP:535627239
343 343 c, t dbSNP:754291669
349 349 g, t dbSNP:757670376
352 352 c, t dbSNP:779335034
353 353 a, g dbSNP:145616631
356 356 a, c dbSNP:758481098
359 359 a, g dbSNP:780194184
363 363 a, g dbSNP:747022200
372 372 a, g, t dbSNP:151040226
374 374 a, g dbSNP:747994812
379 379 c, g dbSNP:769577154
381 381 a, g dbSNP:772928706
386 386 g, t dbSNP:762683437
401 401 c, t dbSNP:373096675
409 409 a, g dbSNP:770383127
413 413 a, t dbSNP:773580529
432 432 c, t dbSNP:367574730
436 436 c, t dbSNP:766658781
442 442 c, g dbSNP:774723481
443 443 a, c dbSNP:759780830
449 449 a, c, t dbSNP:755233768
452 452 a, g dbSNP:572576746
461 461 a, g dbSNP:756162021
467 467 -, aa dbSNP:772219112
472 472 a, g dbSNP:764146390
473 473 c, g dbSNP:370174263
480 480 c, t dbSNP:753711279
481 481 a, g dbSNP:757151603
482 482 c, t dbSNP:778585796
483 483 a, g dbSNP:768954974
487 487 c, t dbSNP:758154733
498 498 a, c dbSNP:140920079
512 512 a, g dbSNP:150187184
519 519 a, g dbSNP:768048172
520 520 a, t dbSNP:776140713
531 531 c, t dbSNP:113028338
532 532 c, t dbSNP:749776601
535 535 c, t dbSNP:113652589
536 536 a, g dbSNP:560146405
543 543 a, c dbSNP:759866664
545 545 g, t dbSNP:767772474
546 546 a, g dbSNP:775673914
550 550 a, g dbSNP:760871747
556 556 c, t dbSNP:114594435
562 562 a, g dbSNP:753897175
568 568 a, t dbSNP:766695194
572 572 a, g dbSNP:549312009
576 576 -, atg dbSNP:746877262
581 581 a, g dbSNP:754124809
585 585 a, g dbSNP:182084395
599 599 c, t dbSNP:112750991
611 611 c, t dbSNP:765440733
649 649 a, c dbSNP:752753055
662 662 a, t dbSNP:531889438
694 694 -, a dbSNP:537244040
816 816 a, g dbSNP:191484676
829 829 c, t dbSNP:758457027
853 853 a, g dbSNP:557256888
900 900 ca, tg dbSNP:386754140
900 900 c, t dbSNP:17702
901 901 a, g dbSNP:7935377
902 902 g, t dbSNP:11559025
931 931 c, t dbSNP:750356360
938 938 a, g dbSNP:61132686
979 979 a, g dbSNP:6632
999 999 c, t dbSNP:749056881
1002 1002 a, g dbSNP:747570882
1019 1019 c, t dbSNP:535740464
1134 1134 a, g dbSNP:542625445
1171 1171 a, g dbSNP:377325076
1180 1180 a, g dbSNP:555659135
1184 1184 a, g dbSNP:771298430
1190 1190 c, t dbSNP:552918830
1192 1192 a, g dbSNP:747631379
1218 1218 a, g dbSNP:771584910

Target ORF information:

RefSeq Version NM_017841
Organism Homo sapiens (human)
Definition Homo sapiens succinate dehydrogenase complex assembly factor 2 (SDHAF2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_017841

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGCGGTGT CTACAGTGTT CTCGACTTCG TCGCTGATGC TTGCTCTGTC AAGGCACAGC 
CTATTGTCTC CTTTGCTCAG TGTGACATCA TTCAGACGCT TCTACAGAGG TGACAGCCCA
ACAGATTCCC AAAAGGACAT GATTGAAATC CCTTTGCCTC CATGGCAGGA GAGAACTGAT
GAATCCATAG AAACCAAAAG AGCCCGCCTG CTCTATGAGA GCAGAAAGAG GGGAATGTTG
GAAAACTGCA TTCTTCTTAG TCTTTTTGCT AAAGAACATC TGCAGCACAT GACAGAAAAG
CAGCTGAACC TCTATGACCG CCTGATTAAC GAGCCTAGTA ATGACTGGGA TATTTACTAC
TGGGCCACAG AAGCTAAACC AGCCCCAGAA ATATTTGAAA ATGAAGTCAT GGCCCTGCTG
AGAGACTTTG CTAAAAACAA AAACAAAGAG CAGAGACTGC GTGCCCCAGA TCTTGAGTAC
CTCTTTGAAA AGCCACGTTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.