The following CLN6 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CLN6 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||Documents for ORF clone product in dufault vector
||ORF Nucleotide Sequence (Length: 936bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||ceroid-lipofuscinosis neuronal protein 6
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BM149330.1, AK027604.1,
BC013130.1, CN427564.1, BC010849.1 and CA446197.1.
This sequence is a reference standard in the RefSeqGene project.
On Oct 17, 2008 this sequence version replaced gi:8923531.
Summary: This gene is one of eight which have been associated with
neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten
disease, NCL comprises a class of autosomal recessive,
neurodegenerative disorders affecting children. The genes
responsible likely encode proteins involved in the degradation of
post-translationally modified proteins in lysosomes. The primary
defect in NCL disorders is thought to be associated with lysosomal
storage function. [provided by RefSeq, Oct 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: AK000568.1, AK027604.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
COMPLETENESS: complete on the 3' end.