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MAGOHB cDNA ORF clone, Homo sapiens (human)

Gene Symbol MAGOHB
Entrez Gene ID 55110
Full Name mago homolog B, exon junction complex core component
Synonyms MGN2, mago, magoh
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12p13.2

Summary lac of sum

mRNA and Protein(s)

mRNA Protein Name
NM_018048 NP_060518 protein mago nashi homolog 2 isoform 1
NM_001300739 NP_001287668 protein mago nashi homolog 2 isoform 2
XM_005253402 XP_005253459 protein mago nashi homolog 2 isoform X1
XM_011520718 XP_011519020 protein mago nashi homolog 2 isoform X1



Homo sapiens (human) MAGOHB NP_060518.1
Pan troglodytes (chimpanzee) MAGOHB XP_520743.2
Macaca mulatta (Rhesus monkey) MAGOHB XP_001115401.2
Bos taurus (cattle) MAGOHB NP_001069720.1
Mus musculus (house mouse) Magohb NP_079840.2
Rattus norvegicus (Norway rat) Magohb NP_001178034.1
Danio rerio (zebrafish) magoh NP_001017700.1
Drosophila melanogaster (fruit fly) mago NP_476636.1
Caenorhabditis elegans mag-1 NP_493025.1
Arabidopsis thaliana (thale cress) MAGO NP_171716.1
Xenopus (Silurana) tropicalis (western clawed frog) magoh XP_002931471.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MAGOHB gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGOHB cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu17744
NM_018048 Homo sapiens mago homolog B, exon junction complex core component (MAGOHB), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu46132 NM_001300739 Homo sapiens mago homolog B, exon junction complex core component (MAGOHB), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu46132 XM_005253402 PREDICTED: Homo sapiens mago-nashi homolog B (Drosophila) (MAGOHB), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $69.30
$99.00
OHu46132 XM_011520718 PREDICTED: Homo sapiens mago-nashi homolog B (Drosophila) (MAGOHB), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu17744
Clone ID Related Accession (Same CDS sequence) NM_018048
Accession Version NM_018048.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 447bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-JUL-2015
Organism Homo sapiens (human)
Product protein mago nashi homolog 2 isoform 1
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BG533740.1, CD357202.1, AF165518.1 and AC021049.12. On Sep 16, 2010 this sequence version replaced gi:21361685. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BG533740.1, AK022720.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
ATGGCTGTGG CTAGCGATTT CTACCTGCGC TACTACGTAG GGCACAAGGG CAAGTTTGGG 
CACGAGTTTC TGGAGTTCGA ATTTCGGCCG GACGGAAAGC TTAGATATGC CAACAACAGC
AATTACAAAA ATGATGTCAT GATCAGAAAA GAGGCTTATG TGCACAAGAG TGTAATGGAA
GAACTGAAGA GAATTATTGA TGACAGTGAA ATTACAAAAG AAGATGATGC TTTGTGGCCT
CCCCCTGATA GGGTTGGCCG ACAGGAGCTT GAAATTGTAA TTGGAGATGA GCACATATCT
TTTACCACAT CAAAAATAGG TTCTCTTATT GATGTAAATC AGTCAAAGGA TCCTGAAGGC
CTTCGAGTAT TTTACTATTT GGTACAAGAC TTGAAATGTT TAGTTTTCAG TCTTATTGGA
TTACACTTCA AGATTAAACC AATTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_060518.1
CDS78..524
Misc Feature(1)12..14(+)
Misc Feature(2)81..83(+)
Misc Feature(3)93..521(+)
Misc Feature(4)114..521(+)
Misc Feature(5)114..518(+)
Misc Feature(6)120..392(+)
Misc Feature(7)123..506(+)
Misc Feature(8)168..509(+)
Misc Feature(9)279..404(+)
Exon (1)1..171
Gene:MAGOHB
Gene Synonym:
Exon (2)172..230
Gene:MAGOHB
Gene Synonym:
Exon (3)231..341
Gene:MAGOHB
Gene Synonym:
Exon (4)342..424
Gene:MAGOHB
Gene Synonym:
Exon (5)425..3034
Gene:MAGOHB
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_018048
Organism Homo sapiens (human)
Definition Homo sapiens mago homolog B, exon junction complex core component (MAGOHB), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_018048

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCTGTGG CTAGCGATTT CTACCTGCGC TACTACGTAG GGCACAAGGG CAAGTTTGGG 
CACGAGTTTC TGGAGTTCGA ATTTCGGCCG GACGGAAAGC TTAGATATGC CAACAACAGC
AATTACAAAA ATGATGTCAT GATCAGAAAA GAGGCTTATG TGCACAAGAG TGTAATGGAA
GAACTGAAGA GAATTATTGA TGACAGTGAA ATTACAAAAG AAGATGATGC TTTGTGGCCT
CCCCCTGATA GGGTTGGCCG ACAGGAGCTT GAAATTGTAA TTGGAGATGA GCACATATCT
TTTACCACAT CAAAAATAGG TTCTCTTATT GATGTAAATC AGTCAAAGGA TCCTGAAGGC
CTTCGAGTAT TTTACTATTT GGTACAAGAC TTGAAATGTT TAGTTTTCAG TCTTATTGGA
TTACACTTCA AGATTAAACC AATTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu46132
Clone ID Related Accession (Same CDS sequence) NM_001300739 , XM_005253402 , XM_011520718
Accession Version NM_001300739.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 309bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-JUL-2015
Organism Homo sapiens (human)
Product protein mago nashi homolog 2 isoform 2
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC021049.12. Transcript Variant: This variant (2) differs in the 5' structure, resulting in the use of a downstream start codon compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## CDS exon combination :: BF246594.1, BG497574.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
ATGATCAGAA AAGAGGCTTA TGTGCACAAG AGTGTAATGG AAGAACTGAA GAGAATTATT 
GATGACAGTG AAATTACAAA AGAAGATGAT GCTTTGTGGC CTCCCCCTGA TAGGGTTGGC
CGACAGGAGC TTGAAATTGT AATTGGAGAT GAGCACATAT CTTTTACCAC ATCAAAAATA
GGTTCTCTTA TTGATGTAAA TCAGTCAAAG GATCCTGAAG GCCTTCGAGT ATTTTACTAT
TTGGTACAAG ACTTGAAATG TTTAGTTTTC AGTCTTATTG GATTACACTT CAAGATTAAA
CCAATTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001287668.1
CDS384..692
Misc Feature(1)336..338(+)
Misc Feature(2)384..689(+)
Misc Feature(3)384..674(+)
Misc Feature(4)387..689(+)
Misc Feature(5)387..686(+)
Misc Feature(6)402..677(+)
Misc Feature(7)447..572(+)
Exon (1)1..339
Gene:MAGOHB
Gene Synonym:
Exon (2)340..398
Gene:MAGOHB
Gene Synonym:
Exon (3)399..509
Gene:MAGOHB
Gene Synonym:
Exon (4)510..592
Gene:MAGOHB
Gene Synonym:
Exon (5)593..3202
Gene:MAGOHB
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001300739
Organism Homo sapiens (human)
Definition Homo sapiens mago homolog B, exon junction complex core component (MAGOHB), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001300739

ORF Insert Sequence:

1
61
121
181
241
301
ATGATCAGAA AAGAGGCTTA TGTGCACAAG AGTGTAATGG AAGAACTGAA GAGAATTATT 
GATGACAGTG AAATTACAAA AGAAGATGAT GCTTTGTGGC CTCCCCCTGA TAGGGTTGGC
CGACAGGAGC TTGAAATTGT AATTGGAGAT GAGCACATAT CTTTTACCAC ATCAAAAATA
GGTTCTCTTA TTGATGTAAA TCAGTCAAAG GATCCTGAAG GCCTTCGAGT ATTTTACTAT
TTGGTACAAG ACTTGAAATG TTTAGTTTTC AGTCTTATTG GATTACACTT CAAGATTAAA
CCAATTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu46132
Clone ID Related Accession (Same CDS sequence) NM_001300739 , XM_005253402 , XM_011520718
Accession Version XM_005253402.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 309bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product protein mago nashi homolog 2 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_009714.18) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
ATGATCAGAA AAGAGGCTTA TGTGCACAAG AGTGTAATGG AAGAACTGAA GAGAATTATT 
GATGACAGTG AAATTACAAA AGAAGATGAT GCTTTGTGGC CTCCCCCTGA TAGGGTTGGC
CGACAGGAGC TTGAAATTGT AATTGGAGAT GAGCACATAT CTTTTACCAC ATCAAAAATA
GGTTCTCTTA TTGATGTAAA TCAGTCAAAG GATCCTGAAG GCCTTCGAGT ATTTTACTAT
TTGGTACAAG ACTTGAAATG TTTAGTTTTC AGTCTTATTG GATTACACTT CAAGATTAAA
CCAATTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005253459.1
CDS555..863
Misc Feature(1)555..860(+)
Misc Feature(2)555..845(+)
Misc Feature(3)558..860(+)
Misc Feature(4)558..857(+)
Misc Feature(5)573..848(+)
Misc Feature(6)618..743(+)
Translation

Target ORF information:

RefSeq Version XM_005253402
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens mago-nashi homolog B (Drosophila) (MAGOHB), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005253402

ORF Insert Sequence:

1
61
121
181
241
301
ATGATCAGAA AAGAGGCTTA TGTGCACAAG AGTGTAATGG AAGAACTGAA GAGAATTATT 
GATGACAGTG AAATTACAAA AGAAGATGAT GCTTTGTGGC CTCCCCCTGA TAGGGTTGGC
CGACAGGAGC TTGAAATTGT AATTGGAGAT GAGCACATAT CTTTTACCAC ATCAAAAATA
GGTTCTCTTA TTGATGTAAA TCAGTCAAAG GATCCTGAAG GCCTTCGAGT ATTTTACTAT
TTGGTACAAG ACTTGAAATG TTTAGTTTTC AGTCTTATTG GATTACACTT CAAGATTAAA
CCAATTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu46132
Clone ID Related Accession (Same CDS sequence) NM_001300739 , XM_005253402 , XM_011520718
Accession Version XM_011520718.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 309bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product protein mago nashi homolog 2 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_009714.18) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
ATGATCAGAA AAGAGGCTTA TGTGCACAAG AGTGTAATGG AAGAACTGAA GAGAATTATT 
GATGACAGTG AAATTACAAA AGAAGATGAT GCTTTGTGGC CTCCCCCTGA TAGGGTTGGC
CGACAGGAGC TTGAAATTGT AATTGGAGAT GAGCACATAT CTTTTACCAC ATCAAAAATA
GGTTCTCTTA TTGATGTAAA TCAGTCAAAG GATCCTGAAG GCCTTCGAGT ATTTTACTAT
TTGGTACAAG ACTTGAAATG TTTAGTTTTC AGTCTTATTG GATTACACTT CAAGATTAAA
CCAATTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011519020.1
CDS100..408
Misc Feature(1)100..405(+)
Misc Feature(2)100..390(+)
Misc Feature(3)103..405(+)
Misc Feature(4)103..402(+)
Misc Feature(5)118..393(+)
Misc Feature(6)163..288(+)
Translation

Target ORF information:

RefSeq Version XM_011520718
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens mago-nashi homolog B (Drosophila) (MAGOHB), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011520718

ORF Insert Sequence:

1
61
121
181
241
301
ATGATCAGAA AAGAGGCTTA TGTGCACAAG AGTGTAATGG AAGAACTGAA GAGAATTATT 
GATGACAGTG AAATTACAAA AGAAGATGAT GCTTTGTGGC CTCCCCCTGA TAGGGTTGGC
CGACAGGAGC TTGAAATTGT AATTGGAGAT GAGCACATAT CTTTTACCAC ATCAAAAATA
GGTTCTCTTA TTGATGTAAA TCAGTCAAAG GATCCTGAAG GCCTTCGAGT ATTTTACTAT
TTGGTACAAG ACTTGAAATG TTTAGTTTTC AGTCTTATTG GATTACACTT CAAGATTAAA
CCAATTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

A proteome-scale map of the human interactome network
Cell 159 (5), 1212-1226 (2014)
Rolland T, Tasan M, Charloteaux B, Pevzner SJ, Zhong Q, Sahni N, Yi S, Lemmens I, Fontanillo C, Mosca R, Kamburov A, Ghiassian SD, Yang X, Ghamsari L, Balcha D, Begg BE, Braun P, Brehme M, Broly MP, Carvunis AR, Convery-Zupan D, Corominas R, Coulombe-Huntington J, Dann E, Dreze M, Dricot A, Fan C, Franzosa E, Gebreab F, Gutierrez BJ, Hardy MF, Jin M, Kang S, Kiros R, Lin GN, Luck K, MacWilliams A, Menche J, Murray RR, Palagi A, Poulin MM, Rambout X, Rasla J, Reichert P, Romero V, Ruyssinck E, Sahalie JM, Scholz A, Shah AA, Sharma A, Shen Y, Spirohn K, Tam S, Tejeda AO, Trigg SA, Twizere JC, Vega K, Walsh J, Cusick ME, Xia Y, Barabasi AL, Iakoucheva LM, Aloy P, De Las Rivas J, Tavernier J, Calderwood MA, Hill DE, Hao T, Roth FP and Vidal M.


book

Slow co-evolution of the MAGO and Y14 protein families is required for the maintenance of their obligate heterodimerization mode
PLoS ONE 9 (1), E84842 (2014)
Gong P, Zhao M and He C.


book

Two mammalian MAGOH genes contribute to exon junction complex composition and nonsense-mediated decay
RNA Biol 10 (8), 1291-1298 (2013)
Singh KK, Wachsmuth L, Kulozik AE and Gehring NH.


book

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts
Mol. Cell 46 (5), 674-690 (2012)
Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C and Landthaler M.


book

Next-generation sequencing to generate interactome datasets
Nat. Methods 8 (6), 478-480 (2011)
Yu H, Tardivo L, Tam S, Weiner E, Gebreab F, Fan C, Svrzikapa N, Hirozane-Kishikawa T, Rietman E, Yang X, Sahalie J, Salehi-Ashtiani K, Hao T, Cusick ME, Hill DE, Roth FP, Braun P and Vidal M.


book

Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets
Nat. Genet. 38 (3), 285-293 (2006)
Gandhi TK, Zhong J, Mathivanan S, Karthick L, Chandrika KN, Mohan SS, Sharma S, Pinkert S, Nagaraju S, Periaswamy B, Mishra G, Nandakumar K, Shen B, Deshpande N, Nayak R, Sarker M, Boeke JD, Parmigiani G, Schultz J, Bader JS and Pandey A.


book

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization
Curr. Biol. 14 (16), 1436-1450 (2004)
Jin J, Smith FD, Stark C, Wells CD, Fawcett JP, Kulkarni S, Metalnikov P, O'Donnell P, Taylor P, Taylor L, Zougman A, Woodgett JR, Langeberg LK, Scott JD and Pawson T.


 
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