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WRAP53 cDNA ORF clone, Homo sapiens (human)

Gene Symbol WRAP53
Entrez Gene ID 55135
Full Name WD repeat containing, antisense to TP53
Synonyms DKCB3, TCAB1, WDR79
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

17

17p13.1

Summary This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq, Mar 2011]. lac of sum
Disorder MIM:

612661

Disorder Html:





The following WRAP53 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the WRAP53 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu16517 NM_001143991 Homo sapiens WD repeat containing, antisense to TP53 (WRAP53), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$307.30
$439.00
OHu16517 NM_001143990 Homo sapiens WD repeat containing, antisense to TP53 (WRAP53), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$307.30
$439.00
OHu69065 XM_011523952 PREDICTED: Homo sapiens WD repeat containing, antisense to TP53 (WRAP53), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $319.00
OHu16517 NM_018081 Homo sapiens WD repeat containing, antisense to TP53 (WRAP53), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$307.30
$439.00
OHu16517 NM_001143992 Homo sapiens WD repeat containing, antisense to TP53 (WRAP53), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$307.30
$439.00

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu16517
Accession Version NM_001143991.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1647bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 20-APR-2014
Organism Homo sapiens (human)
Product telomerase Cajal body protein 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY766322.1. Summary: This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq, Mar 2011]. Transcript Variant: This variant (3, also known as WRAP53alpha) differs in the 5' UTR compared to variant 1. Variants 1-4 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY766322.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGAAGACTT TGGAGACTCA ACCGTTAGCT CCGGACTGCT GTCCTTCAGA CCAGGACCCA 
GCTCCAGCCC ATCCTTCTCC CCACGCTTCC CCGATGAATA AAAATGCGGA CTCTGAACTG
ATGCCACCGC CTCCCGAAAG GGGGGATCCG CCCCGGTTGT CCCCAGATCC TGTGGCTGGC
TCAGCTGTGT CCCAGGAGCT ACGGGAGGGG GACCCAGTTT CTCTCTCCAC TCCCCTGGAA
ACAGAGTTTG GTTCCCCTAG TGAGTTGAGT CCTCGAATCG AGGAGCAAGA ACTTTCTGAA
AATACAAGCC TTCCTGCAGA AGAAGCAAAC GGGAGCCTTT CTGAAGAAGA AGCGAACGGG
CCAGAGTTGG GGTCTGGAAA AGCCATGGAA GATACCTCTG GGGAACCCGC TGCAGAGGAC
GAGGGAGACA CCGCTTGGAA CTACAGCTTC TCCCAGCTGC CTCGATTTCT CAGTGGTTCC
TGGTCAGAGT TCAGCACCCA ACCTGAGAAC TTCTTGAAAG GCTGTAAGTG GGCTCCTGAC
GGTTCCTGCA TCTTGACCAA TAGTGCTGAT AACATCTTGC GAATTTATAA CCTGCCCCCA
GAGCTGTACC ATGAGGGGGA GCAGGTGGAA TATGCAGAAA TGGTCCCTGT CCTTCGAATG
GTGGAAGGTG ATACCATCTA TGATTACTGC TGGTATTCTC TGATGTCCTC AGCCCAGCCA
GACACCTCCT ACGTGGCCAG CAGCAGCCGG GAGAACCCGA TTCATATCTG GGACGCATTC
ACTGGAGAGC TCCGGGCTTC CTTTCGCGCC TACAACCACC TGGATGAGCT GACGGCAGCC
CATTCGCTCT GCTTCTCCCC GGATGGCTCC CAGCTCTTCT GTGGCTTCAA CCGGACTGTG
CGTGTTTTTT CCACGGCCCG GCCTGGCCGA GACTGCGAGG TCCGAGCCAC ATTTGCAAAA
AAGCAGGGCC AGAGCGGCAT CATCTCCTGC ATAGCCTTCA GCCCAGCCCA GCCCCTCTAT
GCCTGTGGCT CCTACGGCCG CTCCCTGGGT CTGTATGCCT GGGATGATGG CTCCCCTCTC
GCCTTGCTGG GAGGGCACCA AGGGGGCATC ACCCACCTCT GCTTTCATCC CGATGGCAAC
CGCTTCTTCT CAGGAGCCCG CAAGGATGCT GAGCTCCTGT GCTGGGATCT CCGGCAGTCT
GGTTACCCAC TGTGGTCCCT GGGTCGAGAG GTGACCACCA ATCAGCGCAT CTACTTCGAT
CTGGACCCGA CCGGGCAGTT CCTAGTGAGT GGCAGCACGA GCGGGGCTGT CTCTGTGTGG
GACACGGACG GGCCTGGCAA TGATGGGAAG CCGGAGCCCG TGTTGAGTTT TCTGCCCCAG
AAGGACTGCA CCAATGGCGT GAGCCTGCAC CCTAGCCTGC CTCTCCTGGC CACTGCCTCC
GGTCAGCGTG TGTTTCCTGA GCCCACAGAG AGTGGGGACG AAGGAGAGGA GCTGGGCCTT
CCCTTGCTCT CCACGCGCCA CGTCCACCTT GAATGTCGGC TTCAGCTCTG GTGGTGTGGG
GGGGCGCCAG ACTCCAGCAT CCCTGATGAT CACCAGGGCG AGAAAGGGCA GGGAGGAACG
GAGGGAGGTG TGGGTGAGCT GATATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001137463.1
CDS166..1812
Misc Feature(1)160..162(+)
Misc Feature(2)241..243(+)
Misc Feature(3)253..255(+)
Misc Feature(4)325..327(+)
Misc Feature(5)418..420(+)
Misc Feature(6)433..435(+)
Misc Feature(7)499..501(+)
Misc Feature(8)505..507(+)
Misc Feature(9)664..783(+)
Misc Feature(10)688..1605(+)
Misc Feature(11)721..1599(+)
Misc Feature(12)829..966(+)
Misc Feature(13)883..>1605(+)
Misc Feature(14)979..1104(+)
Misc Feature(15)1132..1257(+)
Misc Feature(16)1258..1380(+)
Misc Feature(17)1396..1515(+)
Misc Feature(18)1630..1632(+)
Misc Feature(19)1636..1638(+)
Exon (1)1..164
Gene:WRAP53
Gene Synonym:
Exon (2)165..596
Gene:WRAP53
Gene Synonym:
Exon (3)597..695
Gene:WRAP53
Gene Synonym:
Exon (4)696..807
Gene:WRAP53
Gene Synonym:
Exon (5)808..896
Gene:WRAP53
Gene Synonym:
Exon (6)897..987
Gene:WRAP53
Gene Synonym:
Exon (7)988..1120
Gene:WRAP53
Gene Synonym:
Exon (8)1121..1329
Gene:WRAP53
Gene Synonym:
Exon (9)1330..1433
Gene:WRAP53
Gene Synonym:
Exon (10)1434..1568
Gene:WRAP53
Gene Synonym:
Exon (11)1569..1828
Gene:WRAP53
Gene Synonym:
Translation
Position Chain Variation Link
20 20 a, g dbSNP:17884410
126 126 c, t dbSNP:751266961
179 179 a, g dbSNP:752687945
180 180 a, g dbSNP:376286349
182 182 -, ct dbSNP:764437508
183 183 a, t dbSNP:376621917
189 189 g, t dbSNP:549679591
196 196 c, t dbSNP:17880282
197 197 c, t dbSNP:140694361
200 200 a, c dbSNP:779431250
211 211 g, t dbSNP:150282629
218 218 a, g dbSNP:772549847
234 234 -, ccat dbSNP:754257593
235 235 c, t dbSNP:775043934
239 239 c, t dbSNP:760086957
242 242 c, t dbSNP:768364856
246 246 c, t dbSNP:776077808
249 249 c, t dbSNP:761696793
250 250 a, g dbSNP:765073967
251 251 a, c dbSNP:750219808
276 276 c, t dbSNP:763023897
298 298 c, t dbSNP:139002536
300 300 c, t dbSNP:752880493
303 303 a, g dbSNP:142177444
309 309 a, g dbSNP:368220447
310 310 a, g dbSNP:753969788
315 315 a, g dbSNP:372052208
317 317 c, t dbSNP:779303064
319 319 c, t dbSNP:376125064
324 324 g, t dbSNP:762717799
340 340 a, g dbSNP:111897235
345 345 c, g dbSNP:772621341
348 348 a, c dbSNP:780363627
350 350 a, c dbSNP:746530698
352 352 a, g dbSNP:145760222
358 358 c, t dbSNP:776366967
363 363 a, g dbSNP:761413179
367 367 -, c dbSNP:111433356
367 367 c, g dbSNP:2287499
368 368 a, g dbSNP:773199225
369 369 c, g, t dbSNP:200313002
370 370 a, g dbSNP:766422100
378 378 c, t dbSNP:774095773
381 381 a, c dbSNP:760828940
382 382 a, g dbSNP:764037927
386 386 a, c dbSNP:369386615
389 389 g, t dbSNP:753919854
392 392 c, g dbSNP:757516049
395 395 c, t dbSNP:765444563
397 397 a, c dbSNP:750794543
398 398 c, g dbSNP:758707736
411 411 a, g dbSNP:780635910
415 415 g, t dbSNP:747435394
421 421 c, t dbSNP:141850830
424 424 a, c dbSNP:780617002
430 430 c, t dbSNP:372152816
439 439 c, g dbSNP:769637437
445 445 a, g dbSNP:554392556
448 448 a, g dbSNP:749106865
453 453 a, g dbSNP:770580910
462 462 c, t dbSNP:774374559
470 470 c, t dbSNP:759428765
474 474 c, g dbSNP:767462997
480 480 a, t dbSNP:776628490
488 488 a, c, g dbSNP:144238223
489 489 a, c dbSNP:765462600
490 490 g, t dbSNP:750598622
495 495 c, t dbSNP:150180394
500 500 a, g dbSNP:766695794
502 502 c, g dbSNP:751932334
514 514 a, g dbSNP:773992093
515 515 a, c dbSNP:148728256
517 517 a, g, t dbSNP:781719919
523 523 a, g dbSNP:755625682
526 526 c, g, t dbSNP:777588420
537 537 a, g dbSNP:770583524
550 550 a, g dbSNP:774058987
551 551 c, t dbSNP:745658108
554 554 -, a dbSNP:749953879
555 555 a, c dbSNP:771911772
559 559 a, g dbSNP:775352941
560 560 a, c, t dbSNP:201340741
572 572 c, g dbSNP:34067256
574 574 a, g dbSNP:763211473
580 580 a, g dbSNP:766610610
585 585 c, t dbSNP:751935581
588 588 -, gg dbSNP:765624214
591 591 a, g dbSNP:759877669
592 592 a, g dbSNP:767921886
594 594 c, g dbSNP:753206220
598 598 a, c, g, t dbSNP:147226406
599 599 c, t dbSNP:140594263
607 607 a, t dbSNP:764681311
610 610 a, t dbSNP:369563538
611 611 a, c, g dbSNP:753461311
615 615 c, t dbSNP:2287498
617 617 c, g dbSNP:750056345
622 622 c, g, t dbSNP:571153185
631 631 c, t dbSNP:779875361
634 634 c, t dbSNP:746794861
636 636 c, g, t dbSNP:565530006
644 644 c, t dbSNP:781041136
656 656 -, cag dbSNP:758386953
657 657 a, c dbSNP:281865547
660 660 c, t dbSNP:147817526
661 661 a, c dbSNP:770992500
667 667 c, g dbSNP:774466254
684 684 a, g dbSNP:539554212
705 705 a, c dbSNP:775784125
708 708 a, t dbSNP:747404789
709 709 c, t dbSNP:769107489
715 715 a, c, g dbSNP:776832907
716 716 a, t dbSNP:765650726
723 723 c, t dbSNP:772847669
725 725 a, c dbSNP:35762939
745 745 c, t dbSNP:766034158
748 748 a, c dbSNP:751163017
757 757 c, t dbSNP:754797810
764 764 c, g dbSNP:767383199
765 765 a, c dbSNP:35891829
769 769 c, t dbSNP:756132168
775 775 c, t dbSNP:777564749
780 780 a, c, g dbSNP:750517279
781 781 c, g dbSNP:139095498
786 786 a, g dbSNP:200805760
789 789 a, g dbSNP:747278428
811 811 c, t dbSNP:749833877
817 817 c, t dbSNP:771403969
820 820 c, t dbSNP:773908331
821 821 a, g dbSNP:759039161
823 823 a, g dbSNP:371865260
824 824 c, t dbSNP:774944601
828 828 a, g dbSNP:760537751
832 832 a, g dbSNP:763839659
833 833 a, c, g dbSNP:753668696
835 835 c, g dbSNP:765264100
837 837 c, t dbSNP:751696137
842 842 c, t dbSNP:754956678
845 845 a, g dbSNP:767803897
847 847 a, g, t dbSNP:566624166
847 847 -, g dbSNP:755312840
849 849 c, t dbSNP:756328444
865 865 c, g dbSNP:778159976
872 872 c, t dbSNP:749638410
876 876 a, t dbSNP:527734640
881 881 a, t dbSNP:779323513
885 885 a, g dbSNP:199901527
888 888 c, t dbSNP:771431030
889 889 a, g dbSNP:775038177
890 890 c, t dbSNP:746693191
894 894 a, c dbSNP:570343418
897 897 c, t dbSNP:8071451
898 898 a, c, g dbSNP:144944332
903 903 c, t dbSNP:557295928
904 904 a, g dbSNP:149039922
905 905 a, g dbSNP:758898596
914 914 c, g dbSNP:780547823
918 918 c, g dbSNP:751045511
924 924 a, g, t dbSNP:754489792
929 929 a, g dbSNP:375474753
932 932 a, c, t dbSNP:548123219
939 939 c, t dbSNP:369798739
940 940 a, c, g, t dbSNP:566444649
942 942 a, g dbSNP:768679162
945 945 c, t dbSNP:533794855
947 947 a, c, t dbSNP:372757806
957 957 c, g, t dbSNP:143017192
958 958 c, t dbSNP:766817615
959 959 a, g dbSNP:752066677
970 970 c, t dbSNP:755512125
972 972 c, t dbSNP:35307405
973 973 a, g dbSNP:377242828
974 974 c, t dbSNP:755895697
980 980 a, g dbSNP:370140452
983 983 a, c dbSNP:749049836
988 988 c, g dbSNP:776090557
998 998 a, c, t dbSNP:140702003
999 999 a, g, t dbSNP:372166304
1005 1005 c, g dbSNP:200985609
1011 1011 a, g dbSNP:34740153
1019 1019 c, t dbSNP:145799159
1022 1022 c, t dbSNP:779998259
1024 1024 c, g dbSNP:746988654
1025 1025 c, t dbSNP:375280065
1033 1033 c, t dbSNP:754851216
1039 1039 c, g, t dbSNP:371500722
1056 1056 c, t dbSNP:749321958
1058 1058 a, g dbSNP:560038082
1066 1066 c, t dbSNP:774657140
1075 1075 c, t dbSNP:746256314
1079 1079 c, t dbSNP:375033488
1080 1080 a, g, t dbSNP:200147473
1084 1084 c, t dbSNP:149828392
1085 1085 a, g dbSNP:776212278
1093 1093 c, t dbSNP:761173739
1094 1094 a, g dbSNP:764895538
1101 1101 c, t dbSNP:73248508
1102 1102 a, g dbSNP:373141086
1108 1108 c, g dbSNP:766212187
1109 1109 a, g dbSNP:751343013
1140 1140 c, g, t dbSNP:146558070
1141 1141 a, g dbSNP:758704444
1148 1148 c, t dbSNP:369984114
1173 1173 c, t dbSNP:781468333
1181 1181 c, t dbSNP:780213284
1182 1182 c, t dbSNP:748509622
1185 1185 c, t dbSNP:756619906
1199 1199 a, g dbSNP:778192810
1200 1200 a, c, t dbSNP:138784430
1201 1201 a, g dbSNP:538474084
1204 1204 c, t dbSNP:377611540
1205 1205 a, g dbSNP:371006232
1212 1212 -, g dbSNP:759174078
1240 1240 c, t dbSNP:149359927
1245 1245 c, t dbSNP:775212492
1246 1246 a, g dbSNP:760476968
1258 1258 a, g dbSNP:764152004
1260 1260 c, g dbSNP:776674391
1269 1269 a, g dbSNP:761814385
1275 1275 c, t dbSNP:759263242
1291 1291 c, t dbSNP:281865549
1292 1292 a, c dbSNP:375249946
1296 1296 c, t dbSNP:751646242
1297 1297 a, g dbSNP:552807362
1303 1303 a, t dbSNP:755222519
1306 1306 c, t dbSNP:767714126
1307 1307 a, g dbSNP:753075272
1310 1310 a, t dbSNP:375768855
1323 1323 a, c dbSNP:778282703
1324 1324 c, t dbSNP:199669019
1332 1332 g, t dbSNP:749912677
1344 1344 a, g dbSNP:757887987
1346 1346 a, g dbSNP:779681689
1357 1357 c, t dbSNP:281865548
1358 1358 a, g dbSNP:768411006
1365 1365 a, t dbSNP:772838096
1367 1367 -, g dbSNP:35920811
1382 1382 c, g dbSNP:781203702
1388 1388 a, g dbSNP:116535684
1395 1395 g, t dbSNP:184300267
1406 1406 a, g dbSNP:543868835
1408 1408 c, t dbSNP:200723991
1410 1410 a, g dbSNP:565261355
1411 1411 c, t dbSNP:759563684
1413 1413 c, t dbSNP:374225381
1422 1422 c, t dbSNP:140635900
1426 1426 c, g dbSNP:760941679
1429 1429 a, g dbSNP:764296379
1431 1431 c, t dbSNP:376456857
1433 1433 c, t dbSNP:762178428
1437 1437 c, t dbSNP:367678596
1438 1438 a, g dbSNP:567221089
1446 1446 c, g dbSNP:761911830
1463 1463 c, t dbSNP:765684862
1466 1466 a, g dbSNP:531230582
1468 1468 a, g dbSNP:281865550
1473 1473 c, t dbSNP:34016213
1479 1479 -, tgtg dbSNP:763584318
1490 1490 c, t dbSNP:188668951
1491 1491 a, g dbSNP:538443265
1494 1494 c, t dbSNP:371846554
1495 1495 a, g dbSNP:759111012
1497 1497 a, g dbSNP:767311232
1502 1502 g, t dbSNP:1046823
1517 1517 c, t dbSNP:147407953
1518 1518 a, g dbSNP:377204533
1522 1522 c, g dbSNP:752432522
1524 1524 c, t dbSNP:35082161
1525 1525 a, g, t dbSNP:370050251
1527 1527 g, t dbSNP:757191466
1534 1534 c, t dbSNP:778763212
1542 1542 c, t dbSNP:747113105
1552 1552 g, t dbSNP:768680892
1559 1559 a, g dbSNP:776553040
1564 1564 a, g dbSNP:748462203
1573 1573 c, t dbSNP:748109782
1574 1574 a, c dbSNP:770072513
1580 1580 a, g dbSNP:777813887
1581 1581 c, t dbSNP:749704500
1585 1585 a, c, g dbSNP:771464995
1597 1597 a, g dbSNP:760176224
1602 1602 c, g dbSNP:772450459
1604 1604 c, g dbSNP:775066741
1605 1605 c, t dbSNP:760046060
1606 1606 a, g dbSNP:763828661
1613 1613 a, g dbSNP:199522817
1614 1614 c, g, t dbSNP:201034867
1621 1621 c, t dbSNP:201691365
1630 1630 a, c dbSNP:765076522
1631 1631 c, g dbSNP:750216846
1633 1633 a, g dbSNP:758338202
1635 1635 g, t dbSNP:142603882
1644 1644 c, t dbSNP:752847685
1645 1645 c, g dbSNP:35123152
1647 1647 a, g dbSNP:140360074
1649 1649 c, g dbSNP:777880143
1658 1658 c, t dbSNP:139496430
1666 1666 c, t dbSNP:1861948
1675 1675 c, t dbSNP:483352746
1679 1679 c, t dbSNP:376624508
1681 1681 c, t dbSNP:779483078
1682 1682 a, g, t dbSNP:143189042
1686 1686 c, g, t dbSNP:146651237
1687 1687 a, c, g dbSNP:768089496
1690 1690 c, t dbSNP:140721613
1702 1702 c, g, t dbSNP:144549494
1703 1703 a, g dbSNP:762610453
1711 1711 c, t dbSNP:766375350
1721 1721 a, g dbSNP:751494826
1722 1722 -, g, gg dbSNP:766557841
1723 1723 c, g, t dbSNP:146634933
1723 1723 -, g dbSNP:755116516
1724 1724 c, g, t dbSNP:753960173
1725 1725 a, c, g, t dbSNP:577464512
1727 1727 g, t dbSNP:780433406
1728 1728 c, g, t dbSNP:199701086
1729 1729 -, gc dbSNP:781521924
1729 1729 g, t dbSNP:769202794
1730 1730 a, c, g, t dbSNP:7640
1730 1730 -, c dbSNP:373064567
1731 1731 a, g dbSNP:148329158
1732 1732 c, g dbSNP:772815432
1736 1736 a, c dbSNP:758650970
1746 1746 c, t dbSNP:762638365
1751 1751 a, g dbSNP:542482131
1756 1756 a, c dbSNP:561145111
1760 1760 a, t dbSNP:780444705
1764 1764 c, t dbSNP:774180657
1767 1767 a, g dbSNP:759455599
1768 1768 a, g dbSNP:563854971
1769 1769 a, g dbSNP:753976562
1771 1771 a, g dbSNP:80354016
1778 1778 g, t dbSNP:765587386
1780 1780 a, g dbSNP:549557586
1781 1781 a, g dbSNP:758623071
1784 1784 a, c, t dbSNP:375718073
1785 1785 a, g dbSNP:747334430
1791 1791 a, g dbSNP:755455059
1797 1797 a, g dbSNP:781628446
1805 1805 c, t dbSNP:747691719
1806 1806 c, g, t dbSNP:146994329
1810 1810 -, a dbSNP:755839576
1828 1828 a, g dbSNP:748953975

Target ORF information:

RefSeq Version NM_001143991
Organism Homo sapiens (human)
Definition Homo sapiens WD repeat containing, antisense to TP53 (WRAP53), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001143991

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGAAGACTT TGGAGACTCA ACCGTTAGCT CCGGACTGCT GTCCTTCAGA CCAGGACCCA 
GCTCCAGCCC ATCCTTCTCC CCACGCTTCC CCGATGAATA AAAATGCGGA CTCTGAACTG
ATGCCACCGC CTCCCGAAAG GGGGGATCCG CCCCGGTTGT CCCCAGATCC TGTGGCTGGC
TCAGCTGTGT CCCAGGAGCT ACGGGAGGGG GACCCAGTTT CTCTCTCCAC TCCCCTGGAA
ACAGAGTTTG GTTCCCCTAG TGAGTTGAGT CCTCGAATCG AGGAGCAAGA ACTTTCTGAA
AATACAAGCC TTCCTGCAGA AGAAGCAAAC GGGAGCCTTT CTGAAGAAGA AGCGAACGGG
CCAGAGTTGG GGTCTGGAAA AGCCATGGAA GATACCTCTG GGGAACCCGC TGCAGAGGAC
GAGGGAGACA CCGCTTGGAA CTACAGCTTC TCCCAGCTGC CTCGATTTCT CAGTGGTTCC
TGGTCAGAGT TCAGCACCCA ACCTGAGAAC TTCTTGAAAG GCTGTAAGTG GGCTCCTGAC
GGTTCCTGCA TCTTGACCAA TAGTGCTGAT AACATCTTGC GAATTTATAA CCTGCCCCCA
GAGCTGTACC ATGAGGGGGA GCAGGTGGAA TATGCAGAAA TGGTCCCTGT CCTTCGAATG
GTGGAAGGTG ATACCATCTA TGATTACTGC TGGTATTCTC TGATGTCCTC AGCCCAGCCA
GACACCTCCT ACGTGGCCAG CAGCAGCCGG GAGAACCCGA TTCATATCTG GGACGCATTC
ACTGGAGAGC TCCGGGCTTC CTTTCGCGCC TACAACCACC TGGATGAGCT GACGGCAGCC
CATTCGCTCT GCTTCTCCCC GGATGGCTCC CAGCTCTTCT GTGGCTTCAA CCGGACTGTG
CGTGTTTTTT CCACGGCCCG GCCTGGCCGA GACTGCGAGG TCCGAGCCAC ATTTGCAAAA
AAGCAGGGCC AGAGCGGCAT CATCTCCTGC ATAGCCTTCA GCCCAGCCCA GCCCCTCTAT
GCCTGTGGCT CCTACGGCCG CTCCCTGGGT CTGTATGCCT GGGATGATGG CTCCCCTCTC
GCCTTGCTGG GAGGGCACCA AGGGGGCATC ACCCACCTCT GCTTTCATCC CGATGGCAAC
CGCTTCTTCT CAGGAGCCCG CAAGGATGCT GAGCTCCTGT GCTGGGATCT CCGGCAGTCT
GGTTACCCAC TGTGGTCCCT GGGTCGAGAG GTGACCACCA ATCAGCGCAT CTACTTCGAT
CTGGACCCGA CCGGGCAGTT CCTAGTGAGT GGCAGCACGA GCGGGGCTGT CTCTGTGTGG
GACACGGACG GGCCTGGCAA TGATGGGAAG CCGGAGCCCG TGTTGAGTTT TCTGCCCCAG
AAGGACTGCA CCAATGGCGT GAGCCTGCAC CCTAGCCTGC CTCTCCTGGC CACTGCCTCC
GGTCAGCGTG TGTTTCCTGA GCCCACAGAG AGTGGGGACG AAGGAGAGGA GCTGGGCCTT
CCCTTGCTCT CCACGCGCCA CGTCCACCTT GAATGTCGGC TTCAGCTCTG GTGGTGTGGG
GGGGCGCCAG ACTCCAGCAT CCCTGATGAT CACCAGGGCG AGAAAGGGCA GGGAGGAACG
GAGGGAGGTG TGGGTGAGCT GATATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16517
Accession Version NM_001143990.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1647bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 20-APR-2014
Organism Homo sapiens (human)
Product telomerase Cajal body protein 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ431241.1. Summary: This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq, Mar 2011]. Transcript Variant: This variant (2, also known as WRAP53gamma) differs in the 5' UTR compared to variant 1. Variants 1-4 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ431241.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGAAGACTT TGGAGACTCA ACCGTTAGCT CCGGACTGCT GTCCTTCAGA CCAGGACCCA 
GCTCCAGCCC ATCCTTCTCC CCACGCTTCC CCGATGAATA AAAATGCGGA CTCTGAACTG
ATGCCACCGC CTCCCGAAAG GGGGGATCCG CCCCGGTTGT CCCCAGATCC TGTGGCTGGC
TCAGCTGTGT CCCAGGAGCT ACGGGAGGGG GACCCAGTTT CTCTCTCCAC TCCCCTGGAA
ACAGAGTTTG GTTCCCCTAG TGAGTTGAGT CCTCGAATCG AGGAGCAAGA ACTTTCTGAA
AATACAAGCC TTCCTGCAGA AGAAGCAAAC GGGAGCCTTT CTGAAGAAGA AGCGAACGGG
CCAGAGTTGG GGTCTGGAAA AGCCATGGAA GATACCTCTG GGGAACCCGC TGCAGAGGAC
GAGGGAGACA CCGCTTGGAA CTACAGCTTC TCCCAGCTGC CTCGATTTCT CAGTGGTTCC
TGGTCAGAGT TCAGCACCCA ACCTGAGAAC TTCTTGAAAG GCTGTAAGTG GGCTCCTGAC
GGTTCCTGCA TCTTGACCAA TAGTGCTGAT AACATCTTGC GAATTTATAA CCTGCCCCCA
GAGCTGTACC ATGAGGGGGA GCAGGTGGAA TATGCAGAAA TGGTCCCTGT CCTTCGAATG
GTGGAAGGTG ATACCATCTA TGATTACTGC TGGTATTCTC TGATGTCCTC AGCCCAGCCA
GACACCTCCT ACGTGGCCAG CAGCAGCCGG GAGAACCCGA TTCATATCTG GGACGCATTC
ACTGGAGAGC TCCGGGCTTC CTTTCGCGCC TACAACCACC TGGATGAGCT GACGGCAGCC
CATTCGCTCT GCTTCTCCCC GGATGGCTCC CAGCTCTTCT GTGGCTTCAA CCGGACTGTG
CGTGTTTTTT CCACGGCCCG GCCTGGCCGA GACTGCGAGG TCCGAGCCAC ATTTGCAAAA
AAGCAGGGCC AGAGCGGCAT CATCTCCTGC ATAGCCTTCA GCCCAGCCCA GCCCCTCTAT
GCCTGTGGCT CCTACGGCCG CTCCCTGGGT CTGTATGCCT GGGATGATGG CTCCCCTCTC
GCCTTGCTGG GAGGGCACCA AGGGGGCATC ACCCACCTCT GCTTTCATCC CGATGGCAAC
CGCTTCTTCT CAGGAGCCCG CAAGGATGCT GAGCTCCTGT GCTGGGATCT CCGGCAGTCT
GGTTACCCAC TGTGGTCCCT GGGTCGAGAG GTGACCACCA ATCAGCGCAT CTACTTCGAT
CTGGACCCGA CCGGGCAGTT CCTAGTGAGT GGCAGCACGA GCGGGGCTGT CTCTGTGTGG
GACACGGACG GGCCTGGCAA TGATGGGAAG CCGGAGCCCG TGTTGAGTTT TCTGCCCCAG
AAGGACTGCA CCAATGGCGT GAGCCTGCAC CCTAGCCTGC CTCTCCTGGC CACTGCCTCC
GGTCAGCGTG TGTTTCCTGA GCCCACAGAG AGTGGGGACG AAGGAGAGGA GCTGGGCCTT
CCCTTGCTCT CCACGCGCCA CGTCCACCTT GAATGTCGGC TTCAGCTCTG GTGGTGTGGG
GGGGCGCCAG ACTCCAGCAT CCCTGATGAT CACCAGGGCG AGAAAGGGCA GGGAGGAACG
GAGGGAGGTG TGGGTGAGCT GATATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001137462.1
CDS156..1802
Misc Feature(1)231..233(+)
Misc Feature(2)243..245(+)
Misc Feature(3)315..317(+)
Misc Feature(4)408..410(+)
Misc Feature(5)423..425(+)
Misc Feature(6)489..491(+)
Misc Feature(7)495..497(+)
Misc Feature(8)654..773(+)
Misc Feature(9)678..1595(+)
Misc Feature(10)711..1589(+)
Misc Feature(11)819..956(+)
Misc Feature(12)873..>1595(+)
Misc Feature(13)969..1094(+)
Misc Feature(14)1122..1247(+)
Misc Feature(15)1248..1370(+)
Misc Feature(16)1386..1505(+)
Misc Feature(17)1620..1622(+)
Misc Feature(18)1626..1628(+)
Exon (1)1..154
Gene:WRAP53
Gene Synonym:
Exon (2)155..586
Gene:WRAP53
Gene Synonym:
Exon (3)587..685
Gene:WRAP53
Gene Synonym:
Exon (4)686..797
Gene:WRAP53
Gene Synonym:
Exon (5)798..886
Gene:WRAP53
Gene Synonym:
Exon (6)887..977
Gene:WRAP53
Gene Synonym:
Exon (7)978..1110
Gene:WRAP53
Gene Synonym:
Exon (8)1111..1319
Gene:WRAP53
Gene Synonym:
Exon (9)1320..1423
Gene:WRAP53
Gene Synonym:
Exon (10)1424..1558
Gene:WRAP53
Gene Synonym:
Exon (11)1559..1818
Gene:WRAP53
Gene Synonym:
Translation
Position Chain Variation Link
1 1 a, t dbSNP:566671572
14 14 c, g dbSNP:771996184
16 16 c, t dbSNP:534175315
26 26 g, t dbSNP:555511214
46 46 -, g dbSNP:34975059
66 66 c, t dbSNP:146230720
102 102 a, t dbSNP:537903606
116 116 c, t dbSNP:556250319
124 124 c, t dbSNP:193086249
131 131 a, g dbSNP:139240810
169 169 a, g dbSNP:752687945
170 170 a, g dbSNP:376286349
172 172 -, ct dbSNP:764437508
173 173 a, t dbSNP:376621917
179 179 g, t dbSNP:549679591
186 186 c, t dbSNP:17880282
187 187 c, t dbSNP:140694361
190 190 a, c dbSNP:779431250
201 201 g, t dbSNP:150282629
208 208 a, g dbSNP:772549847
224 224 -, ccat dbSNP:754257593
225 225 c, t dbSNP:775043934
229 229 c, t dbSNP:760086957
232 232 c, t dbSNP:768364856
236 236 c, t dbSNP:776077808
239 239 c, t dbSNP:761696793
240 240 a, g dbSNP:765073967
241 241 a, c dbSNP:750219808
266 266 c, t dbSNP:763023897
288 288 c, t dbSNP:139002536
290 290 c, t dbSNP:752880493
293 293 a, g dbSNP:142177444
299 299 a, g dbSNP:368220447
300 300 a, g dbSNP:753969788
305 305 a, g dbSNP:372052208
307 307 c, t dbSNP:779303064
309 309 c, t dbSNP:376125064
314 314 g, t dbSNP:762717799
330 330 a, g dbSNP:111897235
335 335 c, g dbSNP:772621341
338 338 a, c dbSNP:780363627
340 340 a, c dbSNP:746530698
342 342 a, g dbSNP:145760222
348 348 c, t dbSNP:776366967
353 353 a, g dbSNP:761413179
357 357 -, c dbSNP:111433356
357 357 c, g dbSNP:2287499
358 358 a, g dbSNP:773199225
359 359 c, g, t dbSNP:200313002
360 360 a, g dbSNP:766422100
368 368 c, t dbSNP:774095773
371 371 a, c dbSNP:760828940
372 372 a, g dbSNP:764037927
376 376 a, c dbSNP:369386615
379 379 g, t dbSNP:753919854
382 382 c, g dbSNP:757516049
385 385 c, t dbSNP:765444563
387 387 a, c dbSNP:750794543
388 388 c, g dbSNP:758707736
401 401 a, g dbSNP:780635910
405 405 g, t dbSNP:747435394
411 411 c, t dbSNP:141850830
414 414 a, c dbSNP:780617002
420 420 c, t dbSNP:372152816
429 429 c, g dbSNP:769637437
435 435 a, g dbSNP:554392556
438 438 a, g dbSNP:749106865
443 443 a, g dbSNP:770580910
452 452 c, t dbSNP:774374559
460 460 c, t dbSNP:759428765
464 464 c, g dbSNP:767462997
470 470 a, t dbSNP:776628490
478 478 a, c, g dbSNP:144238223
479 479 a, c dbSNP:765462600
480 480 g, t dbSNP:750598622
485 485 c, t dbSNP:150180394
490 490 a, g dbSNP:766695794
492 492 c, g dbSNP:751932334
504 504 a, g dbSNP:773992093
505 505 a, c dbSNP:148728256
507 507 a, g, t dbSNP:781719919
513 513 a, g dbSNP:755625682
516 516 c, g, t dbSNP:777588420
527 527 a, g dbSNP:770583524
540 540 a, g dbSNP:774058987
541 541 c, t dbSNP:745658108
544 544 -, a dbSNP:749953879
545 545 a, c dbSNP:771911772
549 549 a, g dbSNP:775352941
550 550 a, c, t dbSNP:201340741
562 562 c, g dbSNP:34067256
564 564 a, g dbSNP:763211473
570 570 a, g dbSNP:766610610
575 575 c, t dbSNP:751935581
578 578 -, gg dbSNP:765624214
581 581 a, g dbSNP:759877669
582 582 a, g dbSNP:767921886
584 584 c, g dbSNP:753206220
588 588 a, c, g, t dbSNP:147226406
589 589 c, t dbSNP:140594263
597 597 a, t dbSNP:764681311
600 600 a, t dbSNP:369563538
601 601 a, c, g dbSNP:753461311
605 605 c, t dbSNP:2287498
607 607 c, g dbSNP:750056345
612 612 c, g, t dbSNP:571153185
621 621 c, t dbSNP:779875361
624 624 c, t dbSNP:746794861
626 626 c, g, t dbSNP:565530006
634 634 c, t dbSNP:781041136
646 646 -, cag dbSNP:758386953
647 647 a, c dbSNP:281865547
650 650 c, t dbSNP:147817526
651 651 a, c dbSNP:770992500
657 657 c, g dbSNP:774466254
674 674 a, g dbSNP:539554212
695 695 a, c dbSNP:775784125
698 698 a, t dbSNP:747404789
699 699 c, t dbSNP:769107489
705 705 a, c, g dbSNP:776832907
706 706 a, t dbSNP:765650726
713 713 c, t dbSNP:772847669
715 715 a, c dbSNP:35762939
735 735 c, t dbSNP:766034158
738 738 a, c dbSNP:751163017
747 747 c, t dbSNP:754797810
754 754 c, g dbSNP:767383199
755 755 a, c dbSNP:35891829
759 759 c, t dbSNP:756132168
765 765 c, t dbSNP:777564749
770 770 a, c, g dbSNP:750517279
771 771 c, g dbSNP:139095498
776 776 a, g dbSNP:200805760
779 779 a, g dbSNP:747278428
801 801 c, t dbSNP:749833877
807 807 c, t dbSNP:771403969
810 810 c, t dbSNP:773908331
811 811 a, g dbSNP:759039161
813 813 a, g dbSNP:371865260
814 814 c, t dbSNP:774944601
818 818 a, g dbSNP:760537751
822 822 a, g dbSNP:763839659
823 823 a, c, g dbSNP:753668696
825 825 c, g dbSNP:765264100
827 827 c, t dbSNP:751696137
832 832 c, t dbSNP:754956678
835 835 a, g dbSNP:767803897
837 837 a, g, t dbSNP:566624166
837 837 -, g dbSNP:755312840
839 839 c, t dbSNP:756328444
855 855 c, g dbSNP:778159976
862 862 c, t dbSNP:749638410
866 866 a, t dbSNP:527734640
871 871 a, t dbSNP:779323513
875 875 a, g dbSNP:199901527
878 878 c, t dbSNP:771431030
879 879 a, g dbSNP:775038177
880 880 c, t dbSNP:746693191
884 884 a, c dbSNP:570343418
887 887 c, t dbSNP:8071451
888 888 a, c, g dbSNP:144944332
893 893 c, t dbSNP:557295928
894 894 a, g dbSNP:149039922
895 895 a, g dbSNP:758898596
904 904 c, g dbSNP:780547823
908 908 c, g dbSNP:751045511
914 914 a, g, t dbSNP:754489792
919 919 a, g dbSNP:375474753
922 922 a, c, t dbSNP:548123219
929 929 c, t dbSNP:369798739
930 930 a, c, g, t dbSNP:566444649
932 932 a, g dbSNP:768679162
935 935 c, t dbSNP:533794855
937 937 a, c, t dbSNP:372757806
947 947 c, g, t dbSNP:143017192
948 948 c, t dbSNP:766817615
949 949 a, g dbSNP:752066677
960 960 c, t dbSNP:755512125
962 962 c, t dbSNP:35307405
963 963 a, g dbSNP:377242828
964 964 c, t dbSNP:755895697
970 970 a, g dbSNP:370140452
973 973 a, c dbSNP:749049836
978 978 c, g dbSNP:776090557
988 988 a, c, t dbSNP:140702003
989 989 a, g, t dbSNP:372166304
995 995 c, g dbSNP:200985609
1001 1001 a, g dbSNP:34740153
1009 1009 c, t dbSNP:145799159
1012 1012 c, t dbSNP:779998259
1014 1014 c, g dbSNP:746988654
1015 1015 c, t dbSNP:375280065
1023 1023 c, t dbSNP:754851216
1029 1029 c, g, t dbSNP:371500722
1046 1046 c, t dbSNP:749321958
1048 1048 a, g dbSNP:560038082
1056 1056 c, t dbSNP:774657140
1065 1065 c, t dbSNP:746256314
1069 1069 c, t dbSNP:375033488
1070 1070 a, g, t dbSNP:200147473
1074 1074 c, t dbSNP:149828392
1075 1075 a, g dbSNP:776212278
1083 1083 c, t dbSNP:761173739
1084 1084 a, g dbSNP:764895538
1091 1091 c, t dbSNP:73248508
1092 1092 a, g dbSNP:373141086
1098 1098 c, g dbSNP:766212187
1099 1099 a, g dbSNP:751343013
1130 1130 c, g, t dbSNP:146558070
1131 1131 a, g dbSNP:758704444
1138 1138 c, t dbSNP:369984114
1163 1163 c, t dbSNP:781468333
1171 1171 c, t dbSNP:780213284
1172 1172 c, t dbSNP:748509622
1175 1175 c, t dbSNP:756619906
1189 1189 a, g dbSNP:778192810
1190 1190 a, c, t dbSNP:138784430
1191 1191 a, g dbSNP:538474084
1194 1194 c, t dbSNP:377611540
1195 1195 a, g dbSNP:371006232
1202 1202 -, g dbSNP:759174078
1230 1230 c, t dbSNP:149359927
1235 1235 c, t dbSNP:775212492
1236 1236 a, g dbSNP:760476968
1248 1248 a, g dbSNP:764152004
1250 1250 c, g dbSNP:776674391
1259 1259 a, g dbSNP:761814385
1265 1265 c, t dbSNP:759263242
1281 1281 c, t dbSNP:281865549
1282 1282 a, c dbSNP:375249946
1286 1286 c, t dbSNP:751646242
1287 1287 a, g dbSNP:552807362
1293 1293 a, t dbSNP:755222519
1296 1296 c, t dbSNP:767714126
1297 1297 a, g dbSNP:753075272
1300 1300 a, t dbSNP:375768855
1313 1313 a, c dbSNP:778282703
1314 1314 c, t dbSNP:199669019
1322 1322 g, t dbSNP:749912677
1334 1334 a, g dbSNP:757887987
1336 1336 a, g dbSNP:779681689
1347 1347 c, t dbSNP:281865548
1348 1348 a, g dbSNP:768411006
1355 1355 a, t dbSNP:772838096
1357 1357 -, g dbSNP:35920811
1372 1372 c, g dbSNP:781203702
1378 1378 a, g dbSNP:116535684
1385 1385 g, t dbSNP:184300267
1396 1396 a, g dbSNP:543868835
1398 1398 c, t dbSNP:200723991
1400 1400 a, g dbSNP:565261355
1401 1401 c, t dbSNP:759563684
1403 1403 c, t dbSNP:374225381
1412 1412 c, t dbSNP:140635900
1416 1416 c, g dbSNP:760941679
1419 1419 a, g dbSNP:764296379
1421 1421 c, t dbSNP:376456857
1423 1423 c, t dbSNP:762178428
1427 1427 c, t dbSNP:367678596
1428 1428 a, g dbSNP:567221089
1436 1436 c, g dbSNP:761911830
1453 1453 c, t dbSNP:765684862
1456 1456 a, g dbSNP:531230582
1458 1458 a, g dbSNP:281865550
1463 1463 c, t dbSNP:34016213
1469 1469 -, tgtg dbSNP:763584318
1480 1480 c, t dbSNP:188668951
1481 1481 a, g dbSNP:538443265
1484 1484 c, t dbSNP:371846554
1485 1485 a, g dbSNP:759111012
1487 1487 a, g dbSNP:767311232
1492 1492 g, t dbSNP:1046823
1507 1507 c, t dbSNP:147407953
1508 1508 a, g dbSNP:377204533
1512 1512 c, g dbSNP:752432522
1514 1514 c, t dbSNP:35082161
1515 1515 a, g, t dbSNP:370050251
1517 1517 g, t dbSNP:757191466
1524 1524 c, t dbSNP:778763212
1532 1532 c, t dbSNP:747113105
1542 1542 g, t dbSNP:768680892
1549 1549 a, g dbSNP:776553040
1554 1554 a, g dbSNP:748462203
1563 1563 c, t dbSNP:748109782
1564 1564 a, c dbSNP:770072513
1570 1570 a, g dbSNP:777813887
1571 1571 c, t dbSNP:749704500
1575 1575 a, c, g dbSNP:771464995
1587 1587 a, g dbSNP:760176224
1592 1592 c, g dbSNP:772450459
1594 1594 c, g dbSNP:775066741
1595 1595 c, t dbSNP:760046060
1596 1596 a, g dbSNP:763828661
1603 1603 a, g dbSNP:199522817
1604 1604 c, g, t dbSNP:201034867
1611 1611 c, t dbSNP:201691365
1620 1620 a, c dbSNP:765076522
1621 1621 c, g dbSNP:750216846
1623 1623 a, g dbSNP:758338202
1625 1625 g, t dbSNP:142603882
1634 1634 c, t dbSNP:752847685
1635 1635 c, g dbSNP:35123152
1637 1637 a, g dbSNP:140360074
1639 1639 c, g dbSNP:777880143
1648 1648 c, t dbSNP:139496430
1656 1656 c, t dbSNP:1861948
1665 1665 c, t dbSNP:483352746
1669 1669 c, t dbSNP:376624508
1671 1671 c, t dbSNP:779483078
1672 1672 a, g, t dbSNP:143189042
1676 1676 c, g, t dbSNP:146651237
1677 1677 a, c, g dbSNP:768089496
1680 1680 c, t dbSNP:140721613
1692 1692 c, g, t dbSNP:144549494
1693 1693 a, g dbSNP:762610453
1701 1701 c, t dbSNP:766375350
1711 1711 a, g dbSNP:751494826
1712 1712 -, g, gg dbSNP:766557841
1713 1713 c, g, t dbSNP:146634933
1713 1713 -, g dbSNP:755116516
1714 1714 c, g, t dbSNP:753960173
1715 1715 a, c, g, t dbSNP:577464512
1717 1717 g, t dbSNP:780433406
1718 1718 c, g, t dbSNP:199701086
1719 1719 -, gc dbSNP:781521924
1719 1719 g, t dbSNP:769202794
1720 1720 a, c, g, t dbSNP:7640
1720 1720 -, c dbSNP:373064567
1721 1721 a, g dbSNP:148329158
1722 1722 c, g dbSNP:772815432
1726 1726 a, c dbSNP:758650970
1736 1736 c, t dbSNP:762638365
1741 1741 a, g dbSNP:542482131
1746 1746 a, c dbSNP:561145111
1750 1750 a, t dbSNP:780444705
1754 1754 c, t dbSNP:774180657
1757 1757 a, g dbSNP:759455599
1758 1758 a, g dbSNP:563854971
1759 1759 a, g dbSNP:753976562
1761 1761 a, g dbSNP:80354016
1768 1768 g, t dbSNP:765587386
1770 1770 a, g dbSNP:549557586
1771 1771 a, g dbSNP:758623071
1774 1774 a, c, t dbSNP:375718073
1775 1775 a, g dbSNP:747334430
1781 1781 a, g dbSNP:755455059
1787 1787 a, g dbSNP:781628446
1795 1795 c, t dbSNP:747691719
1796 1796 c, g, t dbSNP:146994329
1800 1800 -, a dbSNP:755839576
1818 1818 a, g dbSNP:748953975

Target ORF information:

RefSeq Version NM_001143990
Organism Homo sapiens (human)
Definition Homo sapiens WD repeat containing, antisense to TP53 (WRAP53), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001143990

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGAAGACTT TGGAGACTCA ACCGTTAGCT CCGGACTGCT GTCCTTCAGA CCAGGACCCA 
GCTCCAGCCC ATCCTTCTCC CCACGCTTCC CCGATGAATA AAAATGCGGA CTCTGAACTG
ATGCCACCGC CTCCCGAAAG GGGGGATCCG CCCCGGTTGT CCCCAGATCC TGTGGCTGGC
TCAGCTGTGT CCCAGGAGCT ACGGGAGGGG GACCCAGTTT CTCTCTCCAC TCCCCTGGAA
ACAGAGTTTG GTTCCCCTAG TGAGTTGAGT CCTCGAATCG AGGAGCAAGA ACTTTCTGAA
AATACAAGCC TTCCTGCAGA AGAAGCAAAC GGGAGCCTTT CTGAAGAAGA AGCGAACGGG
CCAGAGTTGG GGTCTGGAAA AGCCATGGAA GATACCTCTG GGGAACCCGC TGCAGAGGAC
GAGGGAGACA CCGCTTGGAA CTACAGCTTC TCCCAGCTGC CTCGATTTCT CAGTGGTTCC
TGGTCAGAGT TCAGCACCCA ACCTGAGAAC TTCTTGAAAG GCTGTAAGTG GGCTCCTGAC
GGTTCCTGCA TCTTGACCAA TAGTGCTGAT AACATCTTGC GAATTTATAA CCTGCCCCCA
GAGCTGTACC ATGAGGGGGA GCAGGTGGAA TATGCAGAAA TGGTCCCTGT CCTTCGAATG
GTGGAAGGTG ATACCATCTA TGATTACTGC TGGTATTCTC TGATGTCCTC AGCCCAGCCA
GACACCTCCT ACGTGGCCAG CAGCAGCCGG GAGAACCCGA TTCATATCTG GGACGCATTC
ACTGGAGAGC TCCGGGCTTC CTTTCGCGCC TACAACCACC TGGATGAGCT GACGGCAGCC
CATTCGCTCT GCTTCTCCCC GGATGGCTCC CAGCTCTTCT GTGGCTTCAA CCGGACTGTG
CGTGTTTTTT CCACGGCCCG GCCTGGCCGA GACTGCGAGG TCCGAGCCAC ATTTGCAAAA
AAGCAGGGCC AGAGCGGCAT CATCTCCTGC ATAGCCTTCA GCCCAGCCCA GCCCCTCTAT
GCCTGTGGCT CCTACGGCCG CTCCCTGGGT CTGTATGCCT GGGATGATGG CTCCCCTCTC
GCCTTGCTGG GAGGGCACCA AGGGGGCATC ACCCACCTCT GCTTTCATCC CGATGGCAAC
CGCTTCTTCT CAGGAGCCCG CAAGGATGCT GAGCTCCTGT GCTGGGATCT CCGGCAGTCT
GGTTACCCAC TGTGGTCCCT GGGTCGAGAG GTGACCACCA ATCAGCGCAT CTACTTCGAT
CTGGACCCGA CCGGGCAGTT CCTAGTGAGT GGCAGCACGA GCGGGGCTGT CTCTGTGTGG
GACACGGACG GGCCTGGCAA TGATGGGAAG CCGGAGCCCG TGTTGAGTTT TCTGCCCCAG
AAGGACTGCA CCAATGGCGT GAGCCTGCAC CCTAGCCTGC CTCTCCTGGC CACTGCCTCC
GGTCAGCGTG TGTTTCCTGA GCCCACAGAG AGTGGGGACG AAGGAGAGGA GCTGGGCCTT
CCCTTGCTCT CCACGCGCCA CGTCCACCTT GAATGTCGGC TTCAGCTCTG GTGGTGTGGG
GGGGCGCCAG ACTCCAGCAT CCCTGATGAT CACCAGGGCG AGAAAGGGCA GGGAGGAACG
GAGGGAGGTG TGGGTGAGCT GATATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu69065
Accession Version XM_011523952.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1008bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product telomerase Cajal body protein 1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_010718.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGTCCCTG TCCTTCGAAT GGTGGAAGGT GATACCATCT ATGATTACTG CTGGTATTCT 
CTGATGTCCT CAGCCCAGCC AGACACCTCC TACGTGGCCA GCAGCAGCCG GGAGAACCCG
ATTCATATCT GGGACGCATT CACTGGAGAG CTCCGGGCTT CCTTTCGCGC CTACAACCAC
CTGGATGAGC TGACGGCAGC CCATTCGCTC TGCTTCTCCC CGGATGGCTC CCAGCTCTTC
TGTGGCTTCA ACCGGACTGT GCGTGTTTTT TCCACGGCCC GGCCTGGCCG AGACTGCGAG
GTCCGAGCCA CATTTGCAAA AAAGCAGGGC CAGAGCGGCA TCATCTCCTG CATAGCCTTC
AGCCCAGCCC AGCCCCTCTA TGCCTGTGGC TCCTACGGCC GCTCCCTGGG TCTGTATGCC
TGGGATGATG GCTCCCCTCT CGCCTTGCTG GGAGGGCACC AAGGGGGCAT CACCCACCTC
TGCTTTCATC CCGATGGCAA CCGCTTCTTC TCAGGAGCCC GCAAGGATGC TGAGCTCCTG
TGCTGGGATC TCCGGCAGTC TGGTTACCCA CTGTGGTCCC TGGGTCGAGA GGTGACCACC
AATCAGCGCA TCTACTTCGA TCTGGACCCG ACCGGGCAGT TCCTAGTGAG TGGCAGCACG
AGCGGGGCTG TCTCTGTGTG GGACACGGAC GGGCCTGGCA ATGATGGGAA GCCGGAGCCC
GTGTTGAGTT TTCTGCCCCA GAAGGACTGC ACCAATGGCG TGAGCCTGCA CCCTAGCCTG
CCTCTCCTGG CCACTGCCTC CGGTCAGCGT GTGTTTCCTG AGCCCACAGA GAGTGGGGAC
GAAGGAGAGG AGCTGGGCCT TCCCTTGCTC TCCACGCGCC ACGTCCACCT TGAATGTCGG
CTTCAGCTCT GGTGGTGTGG GGGGGCGCCA GACTCCAGCA TCCCTGATGA TCACCAGGGC
GAGAAAGGGC AGGGAGGAAC GGAGGGAGGT GTGGGTGAGC TGATATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqXP_011522254.1
CDS202..1209
Misc Feature(1)280..1002(+)
Misc Feature(2)280..>1002(+)
Misc Feature(3)301..996(+)
Translation
Position Chain Variation Link
2 2 a, c, g, t dbSNP:147226406
3 3 c, t dbSNP:140594263
11 11 a, t dbSNP:764681311
14 14 a, t dbSNP:369563538
15 15 a, c, g dbSNP:753461311
19 19 c, t dbSNP:2287498
21 21 c, g dbSNP:750056345
26 26 c, g, t dbSNP:571153185
35 35 c, t dbSNP:779875361
38 38 c, t dbSNP:746794861
40 40 c, g, t dbSNP:565530006
48 48 c, t dbSNP:781041136
60 60 -, cag dbSNP:758386953
61 61 a, c dbSNP:281865547
64 64 c, t dbSNP:147817526
65 65 a, c dbSNP:770992500
71 71 c, g dbSNP:774466254
88 88 a, g dbSNP:539554212
102 102 a, c dbSNP:775784125
105 105 a, t dbSNP:747404789
106 106 c, t dbSNP:769107489
112 112 a, c, g dbSNP:776832907
113 113 a, t dbSNP:765650726
120 120 c, t dbSNP:772847669
122 122 a, c dbSNP:35762939
142 142 c, t dbSNP:766034158
145 145 a, c dbSNP:751163017
154 154 c, t dbSNP:754797810
161 161 c, g dbSNP:767383199
162 162 a, c dbSNP:35891829
166 166 c, t dbSNP:756132168
172 172 c, t dbSNP:777564749
177 177 a, c, g dbSNP:750517279
178 178 c, g dbSNP:139095498
183 183 a, g dbSNP:200805760
186 186 a, g dbSNP:747278428
208 208 c, t dbSNP:749833877
214 214 c, t dbSNP:771403969
217 217 c, t dbSNP:773908331
218 218 a, g dbSNP:759039161
220 220 a, g dbSNP:371865260
221 221 c, t dbSNP:774944601
225 225 a, g dbSNP:760537751
229 229 a, g dbSNP:763839659
230 230 a, c, g dbSNP:753668696
232 232 c, g dbSNP:765264100
234 234 c, t dbSNP:751696137
239 239 c, t dbSNP:754956678
242 242 a, g dbSNP:767803897
244 244 a, g, t dbSNP:566624166
244 244 -, g dbSNP:755312840
246 246 c, t dbSNP:756328444
262 262 c, g dbSNP:778159976
269 269 c, t dbSNP:749638410
273 273 a, t dbSNP:527734640
278 278 a, t dbSNP:779323513
282 282 a, g dbSNP:199901527
285 285 c, t dbSNP:771431030
286 286 a, g dbSNP:775038177
287 287 c, t dbSNP:746693191
291 291 a, c dbSNP:570343418
294 294 c, t dbSNP:8071451
295 295 a, c, g dbSNP:144944332
300 300 c, t dbSNP:557295928
301 301 a, g dbSNP:149039922
302 302 a, g dbSNP:758898596
311 311 c, g dbSNP:780547823
315 315 c, g dbSNP:751045511
321 321 a, g, t dbSNP:754489792
326 326 a, g dbSNP:375474753
329 329 a, c, t dbSNP:548123219
336 336 c, t dbSNP:369798739
337 337 a, c, g, t dbSNP:566444649
339 339 a, g dbSNP:768679162
342 342 c, t dbSNP:533794855
344 344 a, c, t dbSNP:372757806
354 354 c, g, t dbSNP:143017192
355 355 c, t dbSNP:766817615
356 356 a, g dbSNP:752066677
367 367 c, t dbSNP:755512125
369 369 c, t dbSNP:35307405
370 370 a, g dbSNP:377242828
371 371 c, t dbSNP:755895697
377 377 a, g dbSNP:370140452
380 380 a, c dbSNP:749049836
385 385 c, g dbSNP:776090557
395 395 a, c, t dbSNP:140702003
396 396 a, g, t dbSNP:372166304
402 402 c, g dbSNP:200985609
408 408 a, g dbSNP:34740153
416 416 c, t dbSNP:145799159
419 419 c, t dbSNP:779998259
421 421 c, g dbSNP:746988654
422 422 c, t dbSNP:375280065
430 430 c, t dbSNP:754851216
436 436 c, g, t dbSNP:371500722
453 453 c, t dbSNP:749321958
455 455 a, g dbSNP:560038082
463 463 c, t dbSNP:774657140
472 472 c, t dbSNP:746256314
476 476 c, t dbSNP:375033488
477 477 a, g, t dbSNP:200147473
481 481 c, t dbSNP:149828392
482 482 a, g dbSNP:776212278
490 490 c, t dbSNP:761173739
491 491 a, g dbSNP:764895538
498 498 c, t dbSNP:73248508
499 499 a, g dbSNP:373141086
505 505 c, g dbSNP:766212187
506 506 a, g dbSNP:751343013
537 537 c, g, t dbSNP:146558070
538 538 a, g dbSNP:758704444
545 545 c, t dbSNP:369984114
570 570 c, t dbSNP:781468333
578 578 c, t dbSNP:780213284
579 579 c, t dbSNP:748509622
582 582 c, t dbSNP:756619906
596 596 a, g dbSNP:778192810
597 597 a, c, t dbSNP:138784430
598 598 a, g dbSNP:538474084
601 601 c, t dbSNP:377611540
602 602 a, g dbSNP:371006232
609 609 -, g dbSNP:759174078
637 637 c, t dbSNP:149359927
642 642 c, t dbSNP:775212492
643 643 a, g dbSNP:760476968
655 655 a, g dbSNP:764152004
657 657 c, g dbSNP:776674391
666 666 a, g dbSNP:761814385
672 672 c, t dbSNP:759263242
688 688 c, t dbSNP:281865549
689 689 a, c dbSNP:375249946
693 693 c, t dbSNP:751646242
694 694 a, g dbSNP:552807362
700 700 a, t dbSNP:755222519
703 703 c, t dbSNP:767714126
704 704 a, g dbSNP:753075272
707 707 a, t dbSNP:375768855
720 720 a, c dbSNP:778282703
721 721 c, t dbSNP:199669019
729 729 g, t dbSNP:749912677
741 741 a, g dbSNP:757887987
743 743 a, g dbSNP:779681689
754 754 c, t dbSNP:281865548
755 755 a, g dbSNP:768411006
762 762 a, t dbSNP:772838096
764 764 -, g dbSNP:35920811
779 779 c, g dbSNP:781203702
785 785 a, g dbSNP:116535684
792 792 g, t dbSNP:184300267
803 803 a, g dbSNP:543868835
805 805 c, t dbSNP:200723991
807 807 a, g dbSNP:565261355
808 808 c, t dbSNP:759563684
810 810 c, t dbSNP:374225381
819 819 c, t dbSNP:140635900
823 823 c, g dbSNP:760941679
826 826 a, g dbSNP:764296379
828 828 c, t dbSNP:376456857
830 830 c, t dbSNP:762178428
834 834 c, t dbSNP:367678596
835 835 a, g dbSNP:567221089
843 843 c, g dbSNP:761911830
860 860 c, t dbSNP:765684862
863 863 a, g dbSNP:531230582
865 865 a, g dbSNP:281865550
870 870 c, t dbSNP:34016213
876 876 -, tgtg dbSNP:763584318
887 887 c, t dbSNP:188668951
888 888 a, g dbSNP:538443265
891 891 c, t dbSNP:371846554
892 892 a, g dbSNP:759111012
894 894 a, g dbSNP:767311232
899 899 g, t dbSNP:1046823
914 914 c, t dbSNP:147407953
915 915 a, g dbSNP:377204533
919 919 c, g dbSNP:752432522
921 921 c, t dbSNP:35082161
922 922 a, g, t dbSNP:370050251
924 924 g, t dbSNP:757191466
931 931 c, t dbSNP:778763212
939 939 c, t dbSNP:747113105
949 949 g, t dbSNP:768680892
956 956 a, g dbSNP:776553040
961 961 a, g dbSNP:748462203
970 970 c, t dbSNP:748109782
971 971 a, c dbSNP:770072513
977 977 a, g dbSNP:777813887
978 978 c, t dbSNP:749704500
982 982 a, c, g dbSNP:771464995
994 994 a, g dbSNP:760176224
999 999 c, g dbSNP:772450459
1001 1001 c, g dbSNP:775066741
1002 1002 c, t dbSNP:760046060
1003 1003 a, g dbSNP:763828661
1010 1010 a, g dbSNP:199522817
1011 1011 c, g, t dbSNP:201034867
1018 1018 c, t dbSNP:201691365
1027 1027 a, c dbSNP:765076522
1028 1028 c, g dbSNP:750216846
1030 1030 a, g dbSNP:758338202
1032 1032 g, t dbSNP:142603882
1041 1041 c, t dbSNP:752847685
1042 1042 c, g dbSNP:35123152
1044 1044 a, g dbSNP:140360074
1046 1046 c, g dbSNP:777880143
1055 1055 c, t dbSNP:139496430
1063 1063 c, t dbSNP:1861948
1072 1072 c, t dbSNP:483352746
1076 1076 c, t dbSNP:376624508
1078 1078 c, t dbSNP:779483078
1079 1079 a, g, t dbSNP:143189042
1083 1083 c, g, t dbSNP:146651237
1084 1084 a, c, g dbSNP:768089496
1087 1087 c, t dbSNP:140721613
1099 1099 c, g, t dbSNP:144549494
1100 1100 a, g dbSNP:762610453
1108 1108 c, t dbSNP:766375350
1118 1118 a, g dbSNP:751494826
1119 1119 -, g, gg dbSNP:766557841
1120 1120 c, g, t dbSNP:146634933
1120 1120 -, g dbSNP:755116516
1121 1121 c, g, t dbSNP:753960173
1122 1122 a, c, g, t dbSNP:577464512
1124 1124 g, t dbSNP:780433406
1125 1125 c, g, t dbSNP:199701086
1126 1126 -, gc dbSNP:781521924
1126 1126 g, t dbSNP:769202794
1127 1127 a, c, g, t dbSNP:7640
1127 1127 -, c dbSNP:373064567
1128 1128 a, g dbSNP:148329158
1129 1129 c, g dbSNP:772815432
1133 1133 a, c dbSNP:758650970
1143 1143 c, t dbSNP:762638365
1148 1148 a, g dbSNP:542482131
1153 1153 a, c dbSNP:561145111
1157 1157 a, t dbSNP:780444705
1161 1161 c, t dbSNP:774180657
1164 1164 a, g dbSNP:759455599
1165 1165 a, g dbSNP:563854971
1166 1166 a, g dbSNP:753976562
1168 1168 a, g dbSNP:80354016
1175 1175 g, t dbSNP:765587386
1177 1177 a, g dbSNP:549557586
1178 1178 a, g dbSNP:758623071
1181 1181 a, c, t dbSNP:375718073
1182 1182 a, g dbSNP:747334430
1188 1188 a, g dbSNP:755455059
1194 1194 a, g dbSNP:781628446
1202 1202 c, t dbSNP:747691719
1203 1203 c, g, t dbSNP:146994329
1207 1207 -, a dbSNP:755839576
1225 1225 a, g dbSNP:748953975

Target ORF information:

RefSeq Version XM_011523952
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens WD repeat containing, antisense to TP53 (WRAP53), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011523952

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGTCCCTG TCCTTCGAAT GGTGGAAGGT GATACCATCT ATGATTACTG CTGGTATTCT 
CTGATGTCCT CAGCCCAGCC AGACACCTCC TACGTGGCCA GCAGCAGCCG GGAGAACCCG
ATTCATATCT GGGACGCATT CACTGGAGAG CTCCGGGCTT CCTTTCGCGC CTACAACCAC
CTGGATGAGC TGACGGCAGC CCATTCGCTC TGCTTCTCCC CGGATGGCTC CCAGCTCTTC
TGTGGCTTCA ACCGGACTGT GCGTGTTTTT TCCACGGCCC GGCCTGGCCG AGACTGCGAG
GTCCGAGCCA CATTTGCAAA AAAGCAGGGC CAGAGCGGCA TCATCTCCTG CATAGCCTTC
AGCCCAGCCC AGCCCCTCTA TGCCTGTGGC TCCTACGGCC GCTCCCTGGG TCTGTATGCC
TGGGATGATG GCTCCCCTCT CGCCTTGCTG GGAGGGCACC AAGGGGGCAT CACCCACCTC
TGCTTTCATC CCGATGGCAA CCGCTTCTTC TCAGGAGCCC GCAAGGATGC TGAGCTCCTG
TGCTGGGATC TCCGGCAGTC TGGTTACCCA CTGTGGTCCC TGGGTCGAGA GGTGACCACC
AATCAGCGCA TCTACTTCGA TCTGGACCCG ACCGGGCAGT TCCTAGTGAG TGGCAGCACG
AGCGGGGCTG TCTCTGTGTG GGACACGGAC GGGCCTGGCA ATGATGGGAA GCCGGAGCCC
GTGTTGAGTT TTCTGCCCCA GAAGGACTGC ACCAATGGCG TGAGCCTGCA CCCTAGCCTG
CCTCTCCTGG CCACTGCCTC CGGTCAGCGT GTGTTTCCTG AGCCCACAGA GAGTGGGGAC
GAAGGAGAGG AGCTGGGCCT TCCCTTGCTC TCCACGCGCC ACGTCCACCT TGAATGTCGG
CTTCAGCTCT GGTGGTGTGG GGGGGCGCCA GACTCCAGCA TCCCTGATGA TCACCAGGGC
GAGAAAGGGC AGGGAGGAAC GGAGGGAGGT GTGGGTGAGC TGATATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16517
Accession Version NM_018081.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1647bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product telomerase Cajal body protein 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ431240.1 and AK225411.1. This sequence is a reference standard in the RefSeqGene project. On Jan 22, 2009 this sequence version replaced gi:8922395. Summary: This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq, Mar 2011]. Transcript Variant: This variant (1) represents the longest transcript. Variants 1-4 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK056669.1, AK001247.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGAAGACTT TGGAGACTCA ACCGTTAGCT CCGGACTGCT GTCCTTCAGA CCAGGACCCA 
GCTCCAGCCC ATCCTTCTCC CCACGCTTCC CCGATGAATA AAAATGCGGA CTCTGAACTG
ATGCCACCGC CTCCCGAAAG GGGGGATCCG CCCCGGTTGT CCCCAGATCC TGTGGCTGGC
TCAGCTGTGT CCCAGGAGCT ACGGGAGGGG GACCCAGTTT CTCTCTCCAC TCCCCTGGAA
ACAGAGTTTG GTTCCCCTAG TGAGTTGAGT CCTCGAATCG AGGAGCAAGA ACTTTCTGAA
AATACAAGCC TTCCTGCAGA AGAAGCAAAC GGGAGCCTTT CTGAAGAAGA AGCGAACGGG
CCAGAGTTGG GGTCTGGAAA AGCCATGGAA GATACCTCTG GGGAACCCGC TGCAGAGGAC
GAGGGAGACA CCGCTTGGAA CTACAGCTTC TCCCAGCTGC CTCGATTTCT CAGTGGTTCC
TGGTCAGAGT TCAGCACCCA ACCTGAGAAC TTCTTGAAAG GCTGTAAGTG GGCTCCTGAC
GGTTCCTGCA TCTTGACCAA TAGTGCTGAT AACATCTTGC GAATTTATAA CCTGCCCCCA
GAGCTGTACC ATGAGGGGGA GCAGGTGGAA TATGCAGAAA TGGTCCCTGT CCTTCGAATG
GTGGAAGGTG ATACCATCTA TGATTACTGC TGGTATTCTC TGATGTCCTC AGCCCAGCCA
GACACCTCCT ACGTGGCCAG CAGCAGCCGG GAGAACCCGA TTCATATCTG GGACGCATTC
ACTGGAGAGC TCCGGGCTTC CTTTCGCGCC TACAACCACC TGGATGAGCT GACGGCAGCC
CATTCGCTCT GCTTCTCCCC GGATGGCTCC CAGCTCTTCT GTGGCTTCAA CCGGACTGTG
CGTGTTTTTT CCACGGCCCG GCCTGGCCGA GACTGCGAGG TCCGAGCCAC ATTTGCAAAA
AAGCAGGGCC AGAGCGGCAT CATCTCCTGC ATAGCCTTCA GCCCAGCCCA GCCCCTCTAT
GCCTGTGGCT CCTACGGCCG CTCCCTGGGT CTGTATGCCT GGGATGATGG CTCCCCTCTC
GCCTTGCTGG GAGGGCACCA AGGGGGCATC ACCCACCTCT GCTTTCATCC CGATGGCAAC
CGCTTCTTCT CAGGAGCCCG CAAGGATGCT GAGCTCCTGT GCTGGGATCT CCGGCAGTCT
GGTTACCCAC TGTGGTCCCT GGGTCGAGAG GTGACCACCA ATCAGCGCAT CTACTTCGAT
CTGGACCCGA CCGGGCAGTT CCTAGTGAGT GGCAGCACGA GCGGGGCTGT CTCTGTGTGG
GACACGGACG GGCCTGGCAA TGATGGGAAG CCGGAGCCCG TGTTGAGTTT TCTGCCCCAG
AAGGACTGCA CCAATGGCGT GAGCCTGCAC CCTAGCCTGC CTCTCCTGGC CACTGCCTCC
GGTCAGCGTG TGTTTCCTGA GCCCACAGAG AGTGGGGACG AAGGAGAGGA GCTGGGCCTT
CCCTTGCTCT CCACGCGCCA CGTCCACCTT GAATGTCGGC TTCAGCTCTG GTGGTGTGGG
GGGGCGCCAG ACTCCAGCAT CCCTGATGAT CACCAGGGCG AGAAAGGGCA GGGAGGAACG
GAGGGAGGTG TGGGTGAGCT GATATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_060551.2
CDS301..1947
Misc Feature(1)274..276(+)
Misc Feature(2)376..378(+)
Misc Feature(3)388..390(+)
Misc Feature(4)460..462(+)
Misc Feature(5)553..555(+)
Misc Feature(6)568..570(+)
Misc Feature(7)634..636(+)
Misc Feature(8)640..642(+)
Misc Feature(9)799..918(+)
Misc Feature(10)823..1740(+)
Misc Feature(11)856..1734(+)
Misc Feature(12)964..1101(+)
Misc Feature(13)1018..>1740(+)
Misc Feature(14)1114..1239(+)
Misc Feature(15)1267..1392(+)
Misc Feature(16)1393..1515(+)
Misc Feature(17)1531..1650(+)
Misc Feature(18)1765..1767(+)
Misc Feature(19)1771..1773(+)
Exon (1)1..731
Gene:WRAP53
Gene Synonym:
Exon (2)732..830
Gene:WRAP53
Gene Synonym:
Exon (3)831..942
Gene:WRAP53
Gene Synonym:
Exon (4)943..1031
Gene:WRAP53
Gene Synonym:
Exon (5)1032..1122
Gene:WRAP53
Gene Synonym:
Exon (6)1123..1255
Gene:WRAP53
Gene Synonym:
Exon (7)1256..1464
Gene:WRAP53
Gene Synonym:
Exon (8)1465..1568
Gene:WRAP53
Gene Synonym:
Exon (9)1569..1703
Gene:WRAP53
Gene Synonym:
Exon (10)1704..1963
Gene:WRAP53
Gene Synonym:
Translation
Position Chain Variation Link
1 1 a, g dbSNP:560833428
9 9 c, t dbSNP:531543362
46 46 a, g dbSNP:564330662
56 56 c, g dbSNP:17883670
62 62 a, g dbSNP:370181839
76 76 a, c dbSNP:564890743
95 95 a, g dbSNP:17551150
124 124 a, g dbSNP:547538493
153 153 c, t dbSNP:748265946
163 163 c, t dbSNP:79199718
165 165 c, t dbSNP:750849403
168 168 c, t dbSNP:530208087
170 170 a, c dbSNP:548795605
202 202 a, t dbSNP:11539199
253 253 c, t dbSNP:372820855
261 261 a, t dbSNP:761454111
275 275 a, c dbSNP:765268037
278 278 c, g dbSNP:750344241
281 281 c, t dbSNP:755130675
292 292 c, g dbSNP:781470763
293 293 -, c dbSNP:759226877
294 294 c, t dbSNP:570354139
314 314 a, g dbSNP:752687945
315 315 a, g dbSNP:376286349
317 317 -, ct dbSNP:764437508
318 318 a, t dbSNP:376621917
324 324 g, t dbSNP:549679591
331 331 c, t dbSNP:17880282
332 332 c, t dbSNP:140694361
335 335 a, c dbSNP:779431250
346 346 g, t dbSNP:150282629
353 353 a, g dbSNP:772549847
369 369 -, ccat dbSNP:754257593
370 370 c, t dbSNP:775043934
374 374 c, t dbSNP:760086957
377 377 c, t dbSNP:768364856
381 381 c, t dbSNP:776077808
384 384 c, t dbSNP:761696793
385 385 a, g dbSNP:765073967
386 386 a, c dbSNP:750219808
411 411 c, t dbSNP:763023897
433 433 c, t dbSNP:139002536
435 435 c, t dbSNP:752880493
438 438 a, g dbSNP:142177444
444 444 a, g dbSNP:368220447
445 445 a, g dbSNP:753969788
450 450 a, g dbSNP:372052208
452 452 c, t dbSNP:779303064
454 454 c, t dbSNP:376125064
459 459 g, t dbSNP:762717799
475 475 a, g dbSNP:111897235
480 480 c, g dbSNP:772621341
483 483 a, c dbSNP:780363627
485 485 a, c dbSNP:746530698
487 487 a, g dbSNP:145760222
493 493 c, t dbSNP:776366967
498 498 a, g dbSNP:761413179
502 502 -, c dbSNP:111433356
502 502 c, g dbSNP:2287499
503 503 a, g dbSNP:773199225
504 504 c, g, t dbSNP:200313002
505 505 a, g dbSNP:766422100
513 513 c, t dbSNP:774095773
516 516 a, c dbSNP:760828940
517 517 a, g dbSNP:764037927
521 521 a, c dbSNP:369386615
524 524 g, t dbSNP:753919854
527 527 c, g dbSNP:757516049
530 530 c, t dbSNP:765444563
532 532 a, c dbSNP:750794543
533 533 c, g dbSNP:758707736
546 546 a, g dbSNP:780635910
550 550 g, t dbSNP:747435394
556 556 c, t dbSNP:141850830
559 559 a, c dbSNP:780617002
565 565 c, t dbSNP:372152816
574 574 c, g dbSNP:769637437
580 580 a, g dbSNP:554392556
583 583 a, g dbSNP:749106865
588 588 a, g dbSNP:770580910
597 597 c, t dbSNP:774374559
605 605 c, t dbSNP:759428765
609 609 c, g dbSNP:767462997
615 615 a, t dbSNP:776628490
623 623 a, c, g dbSNP:144238223
624 624 a, c dbSNP:765462600
625 625 g, t dbSNP:750598622
630 630 c, t dbSNP:150180394
635 635 a, g dbSNP:766695794
637 637 c, g dbSNP:751932334
649 649 a, g dbSNP:773992093
650 650 a, c dbSNP:148728256
652 652 a, g, t dbSNP:781719919
658 658 a, g dbSNP:755625682
661 661 c, g, t dbSNP:777588420
672 672 a, g dbSNP:770583524
685 685 a, g dbSNP:774058987
686 686 c, t dbSNP:745658108
689 689 -, a dbSNP:749953879
690 690 a, c dbSNP:771911772
694 694 a, g dbSNP:775352941
695 695 a, c, t dbSNP:201340741
707 707 c, g dbSNP:34067256
709 709 a, g dbSNP:763211473
715 715 a, g dbSNP:766610610
720 720 c, t dbSNP:751935581
723 723 -, gg dbSNP:765624214
726 726 a, g dbSNP:759877669
727 727 a, g dbSNP:767921886
729 729 c, g dbSNP:753206220
733 733 a, c, g, t dbSNP:147226406
734 734 c, t dbSNP:140594263
742 742 a, t dbSNP:764681311
745 745 a, t dbSNP:369563538
746 746 a, c, g dbSNP:753461311
750 750 c, t dbSNP:2287498
752 752 c, g dbSNP:750056345
757 757 c, g, t dbSNP:571153185
766 766 c, t dbSNP:779875361
769 769 c, t dbSNP:746794861
771 771 c, g, t dbSNP:565530006
779 779 c, t dbSNP:781041136
791 791 -, cag dbSNP:758386953
792 792 a, c dbSNP:281865547
795 795 c, t dbSNP:147817526
796 796 a, c dbSNP:770992500
802 802 c, g dbSNP:774466254
819 819 a, g dbSNP:539554212
840 840 a, c dbSNP:775784125
843 843 a, t dbSNP:747404789
844 844 c, t dbSNP:769107489
850 850 a, c, g dbSNP:776832907
851 851 a, t dbSNP:765650726
858 858 c, t dbSNP:772847669
860 860 a, c dbSNP:35762939
880 880 c, t dbSNP:766034158
883 883 a, c dbSNP:751163017
892 892 c, t dbSNP:754797810
899 899 c, g dbSNP:767383199
900 900 a, c dbSNP:35891829
904 904 c, t dbSNP:756132168
910 910 c, t dbSNP:777564749
915 915 a, c, g dbSNP:750517279
916 916 c, g dbSNP:139095498
921 921 a, g dbSNP:200805760
924 924 a, g dbSNP:747278428
946 946 c, t dbSNP:749833877
952 952 c, t dbSNP:771403969
955 955 c, t dbSNP:773908331
956 956 a, g dbSNP:759039161
958 958 a, g dbSNP:371865260
959 959 c, t dbSNP:774944601
963 963 a, g dbSNP:760537751
967 967 a, g dbSNP:763839659
968 968 a, c, g dbSNP:753668696
970 970 c, g dbSNP:765264100
972 972 c, t dbSNP:751696137
977 977 c, t dbSNP:754956678
980 980 a, g dbSNP:767803897
982 982 a, g, t dbSNP:566624166
982 982 -, g dbSNP:755312840
984 984 c, t dbSNP:756328444
1000 1000 c, g dbSNP:778159976
1007 1007 c, t dbSNP:749638410
1011 1011 a, t dbSNP:527734640
1016 1016 a, t dbSNP:779323513
1020 1020 a, g dbSNP:199901527
1023 1023 c, t dbSNP:771431030
1024 1024 a, g dbSNP:775038177
1025 1025 c, t dbSNP:746693191
1029 1029 a, c dbSNP:570343418
1032 1032 c, t dbSNP:8071451
1033 1033 a, c, g dbSNP:144944332
1038 1038 c, t dbSNP:557295928
1039 1039 a, g dbSNP:149039922
1040 1040 a, g dbSNP:758898596
1049 1049 c, g dbSNP:780547823
1053 1053 c, g dbSNP:751045511
1059 1059 a, g, t dbSNP:754489792
1064 1064 a, g dbSNP:375474753
1067 1067 a, c, t dbSNP:548123219
1074 1074 c, t dbSNP:369798739
1075 1075 a, c, g, t dbSNP:566444649
1077 1077 a, g dbSNP:768679162
1080 1080 c, t dbSNP:533794855
1082 1082 a, c, t dbSNP:372757806
1092 1092 c, g, t dbSNP:143017192
1093 1093 c, t dbSNP:766817615
1094 1094 a, g dbSNP:752066677
1105 1105 c, t dbSNP:755512125
1107 1107 c, t dbSNP:35307405
1108 1108 a, g dbSNP:377242828
1109 1109 c, t dbSNP:755895697
1115 1115 a, g dbSNP:370140452
1118 1118 a, c dbSNP:749049836
1123 1123 c, g dbSNP:776090557
1133 1133 a, c, t dbSNP:140702003
1134 1134 a, g, t dbSNP:372166304
1140 1140 c, g dbSNP:200985609
1146 1146 a, g dbSNP:34740153
1154 1154 c, t dbSNP:145799159
1157 1157 c, t dbSNP:779998259
1159 1159 c, g dbSNP:746988654
1160 1160 c, t dbSNP:375280065
1168 1168 c, t dbSNP:754851216
1174 1174 c, g, t dbSNP:371500722
1191 1191 c, t dbSNP:749321958
1193 1193 a, g dbSNP:560038082
1201 1201 c, t dbSNP:774657140
1210 1210 c, t dbSNP:746256314
1214 1214 c, t dbSNP:375033488
1215 1215 a, g, t dbSNP:200147473
1219 1219 c, t dbSNP:149828392
1220 1220 a, g dbSNP:776212278
1228 1228 c, t dbSNP:761173739
1229 1229 a, g dbSNP:764895538
1236 1236 c, t dbSNP:73248508
1237 1237 a, g dbSNP:373141086
1243 1243 c, g dbSNP:766212187
1244 1244 a, g dbSNP:751343013
1275 1275 c, g, t dbSNP:146558070
1276 1276 a, g dbSNP:758704444
1283 1283 c, t dbSNP:369984114
1308 1308 c, t dbSNP:781468333
1316 1316 c, t dbSNP:780213284
1317 1317 c, t dbSNP:748509622
1320 1320 c, t dbSNP:756619906
1334 1334 a, g dbSNP:778192810
1335 1335 a, c, t dbSNP:138784430
1336 1336 a, g dbSNP:538474084
1339 1339 c, t dbSNP:377611540
1340 1340 a, g dbSNP:371006232
1347 1347 -, g dbSNP:759174078
1375 1375 c, t dbSNP:149359927
1380 1380 c, t dbSNP:775212492
1381 1381 a, g dbSNP:760476968
1393 1393 a, g dbSNP:764152004
1395 1395 c, g dbSNP:776674391
1404 1404 a, g dbSNP:761814385
1410 1410 c, t dbSNP:759263242
1426 1426 c, t dbSNP:281865549
1427 1427 a, c dbSNP:375249946
1431 1431 c, t dbSNP:751646242
1432 1432 a, g dbSNP:552807362
1438 1438 a, t dbSNP:755222519
1441 1441 c, t dbSNP:767714126
1442 1442 a, g dbSNP:753075272
1445 1445 a, t dbSNP:375768855
1458 1458 a, c dbSNP:778282703
1459 1459 c, t dbSNP:199669019
1467 1467 g, t dbSNP:749912677
1479 1479 a, g dbSNP:757887987
1481 1481 a, g dbSNP:779681689
1492 1492 c, t dbSNP:281865548
1493 1493 a, g dbSNP:768411006
1500 1500 a, t dbSNP:772838096
1502 1502 -, g dbSNP:35920811
1517 1517 c, g dbSNP:781203702
1523 1523 a, g dbSNP:116535684
1530 1530 g, t dbSNP:184300267
1541 1541 a, g dbSNP:543868835
1543 1543 c, t dbSNP:200723991
1545 1545 a, g dbSNP:565261355
1546 1546 c, t dbSNP:759563684
1548 1548 c, t dbSNP:374225381
1557 1557 c, t dbSNP:140635900
1561 1561 c, g dbSNP:760941679
1564 1564 a, g dbSNP:764296379
1566 1566 c, t dbSNP:376456857
1568 1568 c, t dbSNP:762178428
1572 1572 c, t dbSNP:367678596
1573 1573 a, g dbSNP:567221089
1581 1581 c, g dbSNP:761911830
1598 1598 c, t dbSNP:765684862
1601 1601 a, g dbSNP:531230582
1603 1603 a, g dbSNP:281865550
1608 1608 c, t dbSNP:34016213
1614 1614 -, tgtg dbSNP:763584318
1625 1625 c, t dbSNP:188668951
1626 1626 a, g dbSNP:538443265
1629 1629 c, t dbSNP:371846554
1630 1630 a, g dbSNP:759111012
1632 1632 a, g dbSNP:767311232
1637 1637 g, t dbSNP:1046823
1652 1652 c, t dbSNP:147407953
1653 1653 a, g dbSNP:377204533
1657 1657 c, g dbSNP:752432522
1659 1659 c, t dbSNP:35082161
1660 1660 a, g, t dbSNP:370050251
1662 1662 g, t dbSNP:757191466
1669 1669 c, t dbSNP:778763212
1677 1677 c, t dbSNP:747113105
1687 1687 g, t dbSNP:768680892
1694 1694 a, g dbSNP:776553040
1699 1699 a, g dbSNP:748462203
1708 1708 c, t dbSNP:748109782
1709 1709 a, c dbSNP:770072513
1715 1715 a, g dbSNP:777813887
1716 1716 c, t dbSNP:749704500
1720 1720 a, c, g dbSNP:771464995
1732 1732 a, g dbSNP:760176224
1737 1737 c, g dbSNP:772450459
1739 1739 c, g dbSNP:775066741
1740 1740 c, t dbSNP:760046060
1741 1741 a, g dbSNP:763828661
1748 1748 a, g dbSNP:199522817
1749 1749 c, g, t dbSNP:201034867
1756 1756 c, t dbSNP:201691365
1765 1765 a, c dbSNP:765076522
1766 1766 c, g dbSNP:750216846
1768 1768 a, g dbSNP:758338202
1770 1770 g, t dbSNP:142603882
1779 1779 c, t dbSNP:752847685
1780 1780 c, g dbSNP:35123152
1782 1782 a, g dbSNP:140360074
1784 1784 c, g dbSNP:777880143
1793 1793 c, t dbSNP:139496430
1801 1801 c, t dbSNP:1861948
1810 1810 c, t dbSNP:483352746
1814 1814 c, t dbSNP:376624508
1816 1816 c, t dbSNP:779483078
1817 1817 a, g, t dbSNP:143189042
1821 1821 c, g, t dbSNP:146651237
1822 1822 a, c, g dbSNP:768089496
1825 1825 c, t dbSNP:140721613
1837 1837 c, g, t dbSNP:144549494
1838 1838 a, g dbSNP:762610453
1846 1846 c, t dbSNP:766375350
1856 1856 a, g dbSNP:751494826
1857 1857 -, g, gg dbSNP:766557841
1858 1858 c, g, t dbSNP:146634933
1858 1858 -, g dbSNP:755116516
1859 1859 c, g, t dbSNP:753960173
1860 1860 a, c, g, t dbSNP:577464512
1862 1862 g, t dbSNP:780433406
1863 1863 c, g, t dbSNP:199701086
1864 1864 -, gc dbSNP:781521924
1864 1864 g, t dbSNP:769202794
1865 1865 a, c, g, t dbSNP:7640
1865 1865 -, c dbSNP:373064567
1866 1866 a, g dbSNP:148329158
1867 1867 c, g dbSNP:772815432
1871 1871 a, c dbSNP:758650970
1881 1881 c, t dbSNP:762638365
1886 1886 a, g dbSNP:542482131
1891 1891 a, c dbSNP:561145111
1895 1895 a, t dbSNP:780444705
1899 1899 c, t dbSNP:774180657
1902 1902 a, g dbSNP:759455599
1903 1903 a, g dbSNP:563854971
1904 1904 a, g dbSNP:753976562
1906 1906 a, g dbSNP:80354016
1913 1913 g, t dbSNP:765587386
1915 1915 a, g dbSNP:549557586
1916 1916 a, g dbSNP:758623071
1919 1919 a, c, t dbSNP:375718073
1920 1920 a, g dbSNP:747334430
1926 1926 a, g dbSNP:755455059
1932 1932 a, g dbSNP:781628446
1940 1940 c, t dbSNP:747691719
1941 1941 c, g, t dbSNP:146994329
1945 1945 -, a dbSNP:755839576
1963 1963 a, g dbSNP:748953975

Target ORF information:

RefSeq Version NM_018081
Organism Homo sapiens (human)
Definition Homo sapiens WD repeat containing, antisense to TP53 (WRAP53), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_018081

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGAAGACTT TGGAGACTCA ACCGTTAGCT CCGGACTGCT GTCCTTCAGA CCAGGACCCA 
GCTCCAGCCC ATCCTTCTCC CCACGCTTCC CCGATGAATA AAAATGCGGA CTCTGAACTG
ATGCCACCGC CTCCCGAAAG GGGGGATCCG CCCCGGTTGT CCCCAGATCC TGTGGCTGGC
TCAGCTGTGT CCCAGGAGCT ACGGGAGGGG GACCCAGTTT CTCTCTCCAC TCCCCTGGAA
ACAGAGTTTG GTTCCCCTAG TGAGTTGAGT CCTCGAATCG AGGAGCAAGA ACTTTCTGAA
AATACAAGCC TTCCTGCAGA AGAAGCAAAC GGGAGCCTTT CTGAAGAAGA AGCGAACGGG
CCAGAGTTGG GGTCTGGAAA AGCCATGGAA GATACCTCTG GGGAACCCGC TGCAGAGGAC
GAGGGAGACA CCGCTTGGAA CTACAGCTTC TCCCAGCTGC CTCGATTTCT CAGTGGTTCC
TGGTCAGAGT TCAGCACCCA ACCTGAGAAC TTCTTGAAAG GCTGTAAGTG GGCTCCTGAC
GGTTCCTGCA TCTTGACCAA TAGTGCTGAT AACATCTTGC GAATTTATAA CCTGCCCCCA
GAGCTGTACC ATGAGGGGGA GCAGGTGGAA TATGCAGAAA TGGTCCCTGT CCTTCGAATG
GTGGAAGGTG ATACCATCTA TGATTACTGC TGGTATTCTC TGATGTCCTC AGCCCAGCCA
GACACCTCCT ACGTGGCCAG CAGCAGCCGG GAGAACCCGA TTCATATCTG GGACGCATTC
ACTGGAGAGC TCCGGGCTTC CTTTCGCGCC TACAACCACC TGGATGAGCT GACGGCAGCC
CATTCGCTCT GCTTCTCCCC GGATGGCTCC CAGCTCTTCT GTGGCTTCAA CCGGACTGTG
CGTGTTTTTT CCACGGCCCG GCCTGGCCGA GACTGCGAGG TCCGAGCCAC ATTTGCAAAA
AAGCAGGGCC AGAGCGGCAT CATCTCCTGC ATAGCCTTCA GCCCAGCCCA GCCCCTCTAT
GCCTGTGGCT CCTACGGCCG CTCCCTGGGT CTGTATGCCT GGGATGATGG CTCCCCTCTC
GCCTTGCTGG GAGGGCACCA AGGGGGCATC ACCCACCTCT GCTTTCATCC CGATGGCAAC
CGCTTCTTCT CAGGAGCCCG CAAGGATGCT GAGCTCCTGT GCTGGGATCT CCGGCAGTCT
GGTTACCCAC TGTGGTCCCT GGGTCGAGAG GTGACCACCA ATCAGCGCAT CTACTTCGAT
CTGGACCCGA CCGGGCAGTT CCTAGTGAGT GGCAGCACGA GCGGGGCTGT CTCTGTGTGG
GACACGGACG GGCCTGGCAA TGATGGGAAG CCGGAGCCCG TGTTGAGTTT TCTGCCCCAG
AAGGACTGCA CCAATGGCGT GAGCCTGCAC CCTAGCCTGC CTCTCCTGGC CACTGCCTCC
GGTCAGCGTG TGTTTCCTGA GCCCACAGAG AGTGGGGACG AAGGAGAGGA GCTGGGCCTT
CCCTTGCTCT CCACGCGCCA CGTCCACCTT GAATGTCGGC TTCAGCTCTG GTGGTGTGGG
GGGGCGCCAG ACTCCAGCAT CCCTGATGAT CACCAGGGCG AGAAAGGGCA GGGAGGAACG
GAGGGAGGTG TGGGTGAGCT GATATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu16517
Accession Version NM_001143992.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1647bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product telomerase Cajal body protein 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DQ431240.1. Summary: This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq, Mar 2011]. Transcript Variant: This variant (4, also known as WRAP53beta) differs in the 5' UTR compared to variant 1. Variants 1-4 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DQ431240.1, BC002336.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGAAGACTT TGGAGACTCA ACCGTTAGCT CCGGACTGCT GTCCTTCAGA CCAGGACCCA 
GCTCCAGCCC ATCCTTCTCC CCACGCTTCC CCGATGAATA AAAATGCGGA CTCTGAACTG
ATGCCACCGC CTCCCGAAAG GGGGGATCCG CCCCGGTTGT CCCCAGATCC TGTGGCTGGC
TCAGCTGTGT CCCAGGAGCT ACGGGAGGGG GACCCAGTTT CTCTCTCCAC TCCCCTGGAA
ACAGAGTTTG GTTCCCCTAG TGAGTTGAGT CCTCGAATCG AGGAGCAAGA ACTTTCTGAA
AATACAAGCC TTCCTGCAGA AGAAGCAAAC GGGAGCCTTT CTGAAGAAGA AGCGAACGGG
CCAGAGTTGG GGTCTGGAAA AGCCATGGAA GATACCTCTG GGGAACCCGC TGCAGAGGAC
GAGGGAGACA CCGCTTGGAA CTACAGCTTC TCCCAGCTGC CTCGATTTCT CAGTGGTTCC
TGGTCAGAGT TCAGCACCCA ACCTGAGAAC TTCTTGAAAG GCTGTAAGTG GGCTCCTGAC
GGTTCCTGCA TCTTGACCAA TAGTGCTGAT AACATCTTGC GAATTTATAA CCTGCCCCCA
GAGCTGTACC ATGAGGGGGA GCAGGTGGAA TATGCAGAAA TGGTCCCTGT CCTTCGAATG
GTGGAAGGTG ATACCATCTA TGATTACTGC TGGTATTCTC TGATGTCCTC AGCCCAGCCA
GACACCTCCT ACGTGGCCAG CAGCAGCCGG GAGAACCCGA TTCATATCTG GGACGCATTC
ACTGGAGAGC TCCGGGCTTC CTTTCGCGCC TACAACCACC TGGATGAGCT GACGGCAGCC
CATTCGCTCT GCTTCTCCCC GGATGGCTCC CAGCTCTTCT GTGGCTTCAA CCGGACTGTG
CGTGTTTTTT CCACGGCCCG GCCTGGCCGA GACTGCGAGG TCCGAGCCAC ATTTGCAAAA
AAGCAGGGCC AGAGCGGCAT CATCTCCTGC ATAGCCTTCA GCCCAGCCCA GCCCCTCTAT
GCCTGTGGCT CCTACGGCCG CTCCCTGGGT CTGTATGCCT GGGATGATGG CTCCCCTCTC
GCCTTGCTGG GAGGGCACCA AGGGGGCATC ACCCACCTCT GCTTTCATCC CGATGGCAAC
CGCTTCTTCT CAGGAGCCCG CAAGGATGCT GAGCTCCTGT GCTGGGATCT CCGGCAGTCT
GGTTACCCAC TGTGGTCCCT GGGTCGAGAG GTGACCACCA ATCAGCGCAT CTACTTCGAT
CTGGACCCGA CCGGGCAGTT CCTAGTGAGT GGCAGCACGA GCGGGGCTGT CTCTGTGTGG
GACACGGACG GGCCTGGCAA TGATGGGAAG CCGGAGCCCG TGTTGAGTTT TCTGCCCCAG
AAGGACTGCA CCAATGGCGT GAGCCTGCAC CCTAGCCTGC CTCTCCTGGC CACTGCCTCC
GGTCAGCGTG TGTTTCCTGA GCCCACAGAG AGTGGGGACG AAGGAGAGGA GCTGGGCCTT
CCCTTGCTCT CCACGCGCCA CGTCCACCTT GAATGTCGGC TTCAGCTCTG GTGGTGTGGG
GGGGCGCCAG ACTCCAGCAT CCCTGATGAT CACCAGGGCG AGAAAGGGCA GGGAGGAACG
GAGGGAGGTG TGGGTGAGCT GATATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_001137464.1
CDS215..1861
Misc Feature(1)119..121(+)
Misc Feature(2)290..292(+)
Misc Feature(3)302..304(+)
Misc Feature(4)374..376(+)
Misc Feature(5)467..469(+)
Misc Feature(6)482..484(+)
Misc Feature(7)548..550(+)
Misc Feature(8)554..556(+)
Misc Feature(9)713..832(+)
Misc Feature(10)737..1654(+)
Misc Feature(11)770..1648(+)
Misc Feature(12)878..1015(+)
Misc Feature(13)932..>1654(+)
Misc Feature(14)1028..1153(+)
Misc Feature(15)1181..1306(+)
Misc Feature(16)1307..1429(+)
Misc Feature(17)1445..1564(+)
Misc Feature(18)1679..1681(+)
Misc Feature(19)1685..1687(+)
Exon (1)1..213
Gene:WRAP53
Gene Synonym:
Exon (2)214..645
Gene:WRAP53
Gene Synonym:
Exon (3)646..744
Gene:WRAP53
Gene Synonym:
Exon (4)745..856
Gene:WRAP53
Gene Synonym:
Exon (5)857..945
Gene:WRAP53
Gene Synonym:
Exon (6)946..1036
Gene:WRAP53
Gene Synonym:
Exon (7)1037..1169
Gene:WRAP53
Gene Synonym:
Exon (8)1170..1378
Gene:WRAP53
Gene Synonym:
Exon (9)1379..1482
Gene:WRAP53
Gene Synonym:
Exon (10)1483..1617
Gene:WRAP53
Gene Synonym:
Exon (11)1618..1877
Gene:WRAP53
Gene Synonym:
Translation
Position Chain Variation Link
1 1 a, g dbSNP:560833428
9 9 c, t dbSNP:531543362
46 46 a, g dbSNP:564330662
56 56 c, g dbSNP:17883670
62 62 a, g dbSNP:370181839
76 76 a, c dbSNP:564890743
95 95 a, g dbSNP:17551150
124 124 a, g dbSNP:547538493
153 153 c, t dbSNP:748265946
163 163 c, t dbSNP:79199718
165 165 c, t dbSNP:750849403
168 168 c, t dbSNP:530208087
170 170 a, c dbSNP:548795605
202 202 a, t dbSNP:11539199
228 228 a, g dbSNP:752687945
229 229 a, g dbSNP:376286349
231 231 -, ct dbSNP:764437508
232 232 a, t dbSNP:376621917
238 238 g, t dbSNP:549679591
245 245 c, t dbSNP:17880282
246 246 c, t dbSNP:140694361
249 249 a, c dbSNP:779431250
260 260 g, t dbSNP:150282629
267 267 a, g dbSNP:772549847
283 283 -, ccat dbSNP:754257593
284 284 c, t dbSNP:775043934
288 288 c, t dbSNP:760086957
291 291 c, t dbSNP:768364856
295 295 c, t dbSNP:776077808
298 298 c, t dbSNP:761696793
299 299 a, g dbSNP:765073967
300 300 a, c dbSNP:750219808
325 325 c, t dbSNP:763023897
347 347 c, t dbSNP:139002536
349 349 c, t dbSNP:752880493
352 352 a, g dbSNP:142177444
358 358 a, g dbSNP:368220447
359 359 a, g dbSNP:753969788
364 364 a, g dbSNP:372052208
366 366 c, t dbSNP:779303064
368 368 c, t dbSNP:376125064
373 373 g, t dbSNP:762717799
389 389 a, g dbSNP:111897235
394 394 c, g dbSNP:772621341
397 397 a, c dbSNP:780363627
399 399 a, c dbSNP:746530698
401 401 a, g dbSNP:145760222
407 407 c, t dbSNP:776366967
412 412 a, g dbSNP:761413179
416 416 -, c dbSNP:111433356
416 416 c, g dbSNP:2287499
417 417 a, g dbSNP:773199225
418 418 c, g, t dbSNP:200313002
419 419 a, g dbSNP:766422100
427 427 c, t dbSNP:774095773
430 430 a, c dbSNP:760828940
431 431 a, g dbSNP:764037927
435 435 a, c dbSNP:369386615
438 438 g, t dbSNP:753919854
441 441 c, g dbSNP:757516049
444 444 c, t dbSNP:765444563
446 446 a, c dbSNP:750794543
447 447 c, g dbSNP:758707736
460 460 a, g dbSNP:780635910
464 464 g, t dbSNP:747435394
470 470 c, t dbSNP:141850830
473 473 a, c dbSNP:780617002
479 479 c, t dbSNP:372152816
488 488 c, g dbSNP:769637437
494 494 a, g dbSNP:554392556
497 497 a, g dbSNP:749106865
502 502 a, g dbSNP:770580910
511 511 c, t dbSNP:774374559
519 519 c, t dbSNP:759428765
523 523 c, g dbSNP:767462997
529 529 a, t dbSNP:776628490
537 537 a, c, g dbSNP:144238223
538 538 a, c dbSNP:765462600
539 539 g, t dbSNP:750598622
544 544 c, t dbSNP:150180394
549 549 a, g dbSNP:766695794
551 551 c, g dbSNP:751932334
563 563 a, g dbSNP:773992093
564 564 a, c dbSNP:148728256
566 566 a, g, t dbSNP:781719919
572 572 a, g dbSNP:755625682
575 575 c, g, t dbSNP:777588420
586 586 a, g dbSNP:770583524
599 599 a, g dbSNP:774058987
600 600 c, t dbSNP:745658108
603 603 -, a dbSNP:749953879
604 604 a, c dbSNP:771911772
608 608 a, g dbSNP:775352941
609 609 a, c, t dbSNP:201340741
621 621 c, g dbSNP:34067256
623 623 a, g dbSNP:763211473
629 629 a, g dbSNP:766610610
634 634 c, t dbSNP:751935581
637 637 -, gg dbSNP:765624214
640 640 a, g dbSNP:759877669
641 641 a, g dbSNP:767921886
643 643 c, g dbSNP:753206220
647 647 a, c, g, t dbSNP:147226406
648 648 c, t dbSNP:140594263
656 656 a, t dbSNP:764681311
659 659 a, t dbSNP:369563538
660 660 a, c, g dbSNP:753461311
664 664 c, t dbSNP:2287498
666 666 c, g dbSNP:750056345
671 671 c, g, t dbSNP:571153185
680 680 c, t dbSNP:779875361
683 683 c, t dbSNP:746794861
685 685 c, g, t dbSNP:565530006
693 693 c, t dbSNP:781041136
705 705 -, cag dbSNP:758386953
706 706 a, c dbSNP:281865547
709 709 c, t dbSNP:147817526
710 710 a, c dbSNP:770992500
716 716 c, g dbSNP:774466254
733 733 a, g dbSNP:539554212
754 754 a, c dbSNP:775784125
757 757 a, t dbSNP:747404789
758 758 c, t dbSNP:769107489
764 764 a, c, g dbSNP:776832907
765 765 a, t dbSNP:765650726
772 772 c, t dbSNP:772847669
774 774 a, c dbSNP:35762939
794 794 c, t dbSNP:766034158
797 797 a, c dbSNP:751163017
806 806 c, t dbSNP:754797810
813 813 c, g dbSNP:767383199
814 814 a, c dbSNP:35891829
818 818 c, t dbSNP:756132168
824 824 c, t dbSNP:777564749
829 829 a, c, g dbSNP:750517279
830 830 c, g dbSNP:139095498
835 835 a, g dbSNP:200805760
838 838 a, g dbSNP:747278428
860 860 c, t dbSNP:749833877
866 866 c, t dbSNP:771403969
869 869 c, t dbSNP:773908331
870 870 a, g dbSNP:759039161
872 872 a, g dbSNP:371865260
873 873 c, t dbSNP:774944601
877 877 a, g dbSNP:760537751
881 881 a, g dbSNP:763839659
882 882 a, c, g dbSNP:753668696
884 884 c, g dbSNP:765264100
886 886 c, t dbSNP:751696137
891 891 c, t dbSNP:754956678
894 894 a, g dbSNP:767803897
896 896 a, g, t dbSNP:566624166
896 896 -, g dbSNP:755312840
898 898 c, t dbSNP:756328444
914 914 c, g dbSNP:778159976
921 921 c, t dbSNP:749638410
925 925 a, t dbSNP:527734640
930 930 a, t dbSNP:779323513
934 934 a, g dbSNP:199901527
937 937 c, t dbSNP:771431030
938 938 a, g dbSNP:775038177
939 939 c, t dbSNP:746693191
943 943 a, c dbSNP:570343418
946 946 c, t dbSNP:8071451
947 947 a, c, g dbSNP:144944332
952 952 c, t dbSNP:557295928
953 953 a, g dbSNP:149039922
954 954 a, g dbSNP:758898596
963 963 c, g dbSNP:780547823
967 967 c, g dbSNP:751045511
973 973 a, g, t dbSNP:754489792
978 978 a, g dbSNP:375474753
981 981 a, c, t dbSNP:548123219
988 988 c, t dbSNP:369798739
989 989 a, c, g, t dbSNP:566444649
991 991 a, g dbSNP:768679162
994 994 c, t dbSNP:533794855
996 996 a, c, t dbSNP:372757806
1006 1006 c, g, t dbSNP:143017192
1007 1007 c, t dbSNP:766817615
1008 1008 a, g dbSNP:752066677
1019 1019 c, t dbSNP:755512125
1021 1021 c, t dbSNP:35307405
1022 1022 a, g dbSNP:377242828
1023 1023 c, t dbSNP:755895697
1029 1029 a, g dbSNP:370140452
1032 1032 a, c dbSNP:749049836
1037 1037 c, g dbSNP:776090557
1047 1047 a, c, t dbSNP:140702003
1048 1048 a, g, t dbSNP:372166304
1054 1054 c, g dbSNP:200985609
1060 1060 a, g dbSNP:34740153
1068 1068 c, t dbSNP:145799159
1071 1071 c, t dbSNP:779998259
1073 1073 c, g dbSNP:746988654
1074 1074 c, t dbSNP:375280065
1082 1082 c, t dbSNP:754851216
1088 1088 c, g, t dbSNP:371500722
1105 1105 c, t dbSNP:749321958
1107 1107 a, g dbSNP:560038082
1115 1115 c, t dbSNP:774657140
1124 1124 c, t dbSNP:746256314
1128 1128 c, t dbSNP:375033488
1129 1129 a, g, t dbSNP:200147473
1133 1133 c, t dbSNP:149828392
1134 1134 a, g dbSNP:776212278
1142 1142 c, t dbSNP:761173739
1143 1143 a, g dbSNP:764895538
1150 1150 c, t dbSNP:73248508
1151 1151 a, g dbSNP:373141086
1157 1157 c, g dbSNP:766212187
1158 1158 a, g dbSNP:751343013
1189 1189 c, g, t dbSNP:146558070
1190 1190 a, g dbSNP:758704444
1197 1197 c, t dbSNP:369984114
1222 1222 c, t dbSNP:781468333
1230 1230 c, t dbSNP:780213284
1231 1231 c, t dbSNP:748509622
1234 1234 c, t dbSNP:756619906
1248 1248 a, g dbSNP:778192810
1249 1249 a, c, t dbSNP:138784430
1250 1250 a, g dbSNP:538474084
1253 1253 c, t dbSNP:377611540
1254 1254 a, g dbSNP:371006232
1261 1261 -, g dbSNP:759174078
1289 1289 c, t dbSNP:149359927
1294 1294 c, t dbSNP:775212492
1295 1295 a, g dbSNP:760476968
1307 1307 a, g dbSNP:764152004
1309 1309 c, g dbSNP:776674391
1318 1318 a, g dbSNP:761814385
1324 1324 c, t dbSNP:759263242
1340 1340 c, t dbSNP:281865549
1341 1341 a, c dbSNP:375249946
1345 1345 c, t dbSNP:751646242
1346 1346 a, g dbSNP:552807362
1352 1352 a, t dbSNP:755222519
1355 1355 c, t dbSNP:767714126
1356 1356 a, g dbSNP:753075272
1359 1359 a, t dbSNP:375768855
1372 1372 a, c dbSNP:778282703
1373 1373 c, t dbSNP:199669019
1381 1381 g, t dbSNP:749912677
1393 1393 a, g dbSNP:757887987
1395 1395 a, g dbSNP:779681689
1406 1406 c, t dbSNP:281865548
1407 1407 a, g dbSNP:768411006
1414 1414 a, t dbSNP:772838096
1416 1416 -, g dbSNP:35920811
1431 1431 c, g dbSNP:781203702
1437 1437 a, g dbSNP:116535684
1444 1444 g, t dbSNP:184300267
1455 1455 a, g dbSNP:543868835
1457 1457 c, t dbSNP:200723991
1459 1459 a, g dbSNP:565261355
1460 1460 c, t dbSNP:759563684
1462 1462 c, t dbSNP:374225381
1471 1471 c, t dbSNP:140635900
1475 1475 c, g dbSNP:760941679
1478 1478 a, g dbSNP:764296379
1480 1480 c, t dbSNP:376456857
1482 1482 c, t dbSNP:762178428
1486 1486 c, t dbSNP:367678596
1487 1487 a, g dbSNP:567221089
1495 1495 c, g dbSNP:761911830
1512 1512 c, t dbSNP:765684862
1515 1515 a, g dbSNP:531230582
1517 1517 a, g dbSNP:281865550
1522 1522 c, t dbSNP:34016213
1528 1528 -, tgtg dbSNP:763584318
1539 1539 c, t dbSNP:188668951
1540 1540 a, g dbSNP:538443265
1543 1543 c, t dbSNP:371846554
1544 1544 a, g dbSNP:759111012
1546 1546 a, g dbSNP:767311232
1551 1551 g, t dbSNP:1046823
1566 1566 c, t dbSNP:147407953
1567 1567 a, g dbSNP:377204533
1571 1571 c, g dbSNP:752432522
1573 1573 c, t dbSNP:35082161
1574 1574 a, g, t dbSNP:370050251
1576 1576 g, t dbSNP:757191466
1583 1583 c, t dbSNP:778763212
1591 1591 c, t dbSNP:747113105
1601 1601 g, t dbSNP:768680892
1608 1608 a, g dbSNP:776553040
1613 1613 a, g dbSNP:748462203
1622 1622 c, t dbSNP:748109782
1623 1623 a, c dbSNP:770072513
1629 1629 a, g dbSNP:777813887
1630 1630 c, t dbSNP:749704500
1634 1634 a, c, g dbSNP:771464995
1646 1646 a, g dbSNP:760176224
1651 1651 c, g dbSNP:772450459
1653 1653 c, g dbSNP:775066741
1654 1654 c, t dbSNP:760046060
1655 1655 a, g dbSNP:763828661
1662 1662 a, g dbSNP:199522817
1663 1663 c, g, t dbSNP:201034867
1670 1670 c, t dbSNP:201691365
1679 1679 a, c dbSNP:765076522
1680 1680 c, g dbSNP:750216846
1682 1682 a, g dbSNP:758338202
1684 1684 g, t dbSNP:142603882
1693 1693 c, t dbSNP:752847685
1694 1694 c, g dbSNP:35123152
1696 1696 a, g dbSNP:140360074
1698 1698 c, g dbSNP:777880143
1707 1707 c, t dbSNP:139496430
1715 1715 c, t dbSNP:1861948
1724 1724 c, t dbSNP:483352746
1728 1728 c, t dbSNP:376624508
1730 1730 c, t dbSNP:779483078
1731 1731 a, g, t dbSNP:143189042
1735 1735 c, g, t dbSNP:146651237
1736 1736 a, c, g dbSNP:768089496
1739 1739 c, t dbSNP:140721613
1751 1751 c, g, t dbSNP:144549494
1752 1752 a, g dbSNP:762610453
1760 1760 c, t dbSNP:766375350
1770 1770 a, g dbSNP:751494826
1771 1771 -, g, gg dbSNP:766557841
1772 1772 c, g, t dbSNP:146634933
1772 1772 -, g dbSNP:755116516
1773 1773 c, g, t dbSNP:753960173
1774 1774 a, c, g, t dbSNP:577464512
1776 1776 g, t dbSNP:780433406
1777 1777 c, g, t dbSNP:199701086
1778 1778 -, gc dbSNP:781521924
1778 1778 g, t dbSNP:769202794
1779 1779 a, c, g, t dbSNP:7640
1779 1779 -, c dbSNP:373064567
1780 1780 a, g dbSNP:148329158
1781 1781 c, g dbSNP:772815432
1785 1785 a, c dbSNP:758650970
1795 1795 c, t dbSNP:762638365
1800 1800 a, g dbSNP:542482131
1805 1805 a, c dbSNP:561145111
1809 1809 a, t dbSNP:780444705
1813 1813 c, t dbSNP:774180657
1816 1816 a, g dbSNP:759455599
1817 1817 a, g dbSNP:563854971
1818 1818 a, g dbSNP:753976562
1820 1820 a, g dbSNP:80354016
1827 1827 g, t dbSNP:765587386
1829 1829 a, g dbSNP:549557586
1830 1830 a, g dbSNP:758623071
1833 1833 a, c, t dbSNP:375718073
1834 1834 a, g dbSNP:747334430
1840 1840 a, g dbSNP:755455059
1846 1846 a, g dbSNP:781628446
1854 1854 c, t dbSNP:747691719
1855 1855 c, g, t dbSNP:146994329
1859 1859 -, a dbSNP:755839576
1877 1877 a, g dbSNP:748953975

Target ORF information:

RefSeq Version NM_001143992
Organism Homo sapiens (human)
Definition Homo sapiens WD repeat containing, antisense to TP53 (WRAP53), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001143992

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGAAGACTT TGGAGACTCA ACCGTTAGCT CCGGACTGCT GTCCTTCAGA CCAGGACCCA 
GCTCCAGCCC ATCCTTCTCC CCACGCTTCC CCGATGAATA AAAATGCGGA CTCTGAACTG
ATGCCACCGC CTCCCGAAAG GGGGGATCCG CCCCGGTTGT CCCCAGATCC TGTGGCTGGC
TCAGCTGTGT CCCAGGAGCT ACGGGAGGGG GACCCAGTTT CTCTCTCCAC TCCCCTGGAA
ACAGAGTTTG GTTCCCCTAG TGAGTTGAGT CCTCGAATCG AGGAGCAAGA ACTTTCTGAA
AATACAAGCC TTCCTGCAGA AGAAGCAAAC GGGAGCCTTT CTGAAGAAGA AGCGAACGGG
CCAGAGTTGG GGTCTGGAAA AGCCATGGAA GATACCTCTG GGGAACCCGC TGCAGAGGAC
GAGGGAGACA CCGCTTGGAA CTACAGCTTC TCCCAGCTGC CTCGATTTCT CAGTGGTTCC
TGGTCAGAGT TCAGCACCCA ACCTGAGAAC TTCTTGAAAG GCTGTAAGTG GGCTCCTGAC
GGTTCCTGCA TCTTGACCAA TAGTGCTGAT AACATCTTGC GAATTTATAA CCTGCCCCCA
GAGCTGTACC ATGAGGGGGA GCAGGTGGAA TATGCAGAAA TGGTCCCTGT CCTTCGAATG
GTGGAAGGTG ATACCATCTA TGATTACTGC TGGTATTCTC TGATGTCCTC AGCCCAGCCA
GACACCTCCT ACGTGGCCAG CAGCAGCCGG GAGAACCCGA TTCATATCTG GGACGCATTC
ACTGGAGAGC TCCGGGCTTC CTTTCGCGCC TACAACCACC TGGATGAGCT GACGGCAGCC
CATTCGCTCT GCTTCTCCCC GGATGGCTCC CAGCTCTTCT GTGGCTTCAA CCGGACTGTG
CGTGTTTTTT CCACGGCCCG GCCTGGCCGA GACTGCGAGG TCCGAGCCAC ATTTGCAAAA
AAGCAGGGCC AGAGCGGCAT CATCTCCTGC ATAGCCTTCA GCCCAGCCCA GCCCCTCTAT
GCCTGTGGCT CCTACGGCCG CTCCCTGGGT CTGTATGCCT GGGATGATGG CTCCCCTCTC
GCCTTGCTGG GAGGGCACCA AGGGGGCATC ACCCACCTCT GCTTTCATCC CGATGGCAAC
CGCTTCTTCT CAGGAGCCCG CAAGGATGCT GAGCTCCTGT GCTGGGATCT CCGGCAGTCT
GGTTACCCAC TGTGGTCCCT GGGTCGAGAG GTGACCACCA ATCAGCGCAT CTACTTCGAT
CTGGACCCGA CCGGGCAGTT CCTAGTGAGT GGCAGCACGA GCGGGGCTGT CTCTGTGTGG
GACACGGACG GGCCTGGCAA TGATGGGAAG CCGGAGCCCG TGTTGAGTTT TCTGCCCCAG
AAGGACTGCA CCAATGGCGT GAGCCTGCAC CCTAGCCTGC CTCTCCTGGC CACTGCCTCC
GGTCAGCGTG TGTTTCCTGA GCCCACAGAG AGTGGGGACG AAGGAGAGGA GCTGGGCCTT
CCCTTGCTCT CCACGCGCCA CGTCCACCTT GAATGTCGGC TTCAGCTCTG GTGGTGTGGG
GGGGCGCCAG ACTCCAGCAT CCCTGATGAT CACCAGGGCG AGAAAGGGCA GGGAGGAACG
GAGGGAGGTG TGGGTGAGCT GATATAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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