The following PPP2R1A gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PPP2R1A gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 1770bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DC398468.1, BC026733.1 and
On Apr 16, 2010 this sequence version replaced gi:206725413.
Summary: This gene encodes a constant regulatory subunit of protein
phosphatase 2. Protein phosphatase 2 is one of the four major
Ser/Thr phosphatases, and it is implicated in the negative control
of cell growth and division. It consists of a common heteromeric
core enzyme, which is composed of a catalytic subunit and a
constant regulatory subunit, that associates with a variety of
regulatory subunits. The constant regulatory subunit A serves as a
scaffolding molecule to coordinate the assembly of the catalytic
subunit and a variable regulatory B subunit. This gene encodes an
alpha isoform of the constant regulatory subunit A. Alternatively
spliced transcript variants have been described. [provided by
RefSeq, Apr 2010].
Transcript Variant: This variant (1) represents the longer
transcript and encodes the functional protein.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: AK290593.1, BC026733.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.