The following NOP10 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NOP10 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 195bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||H/ACA ribonucleoprotein complex subunit 3
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BQ218536.1 and BM554889.1.
This sequence is a reference standard in the RefSeqGene project.
On Oct 18, 2005 this sequence version replaced gi:15011920.
Summary: This gene is a member of the H/ACA snoRNPs (small
nucleolar ribonucleoproteins) gene family. snoRNPs are involved in
various aspects of rRNA processing and modification and have been
classified into two families: C/D and H/ACA. The H/ACA snoRNPs also
include the DKC1, NOLA1 and NOLA2 proteins. These four H/ACA snoRNP
proteins localize to the dense fibrillar components of nucleoli and
to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production
and rRNA pseudouridylation are impaired if any one of the four
proteins is depleted. The four H/ACA snoRNP proteins are also
components of the telomerase complex. This gene encodes a protein
related to Saccharomyces cerevisiae Nop10p. [provided by RefSeq,
Transcript exon combination :: BU955288.1, AB043104.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.