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POLR3B polymerase (RNA) III (DNA directed) polypeptide B [Homo sapiens (human)]

Gene Symbol POLR3B
Entrez Gene ID 55703
Full Name polymerase (RNA) III (DNA directed) polypeptide B
Synonyms C128, HLD8, INMAP, RPC2
General protein information
Preferred Names
DNA-directed RNA polymerase III subunit RPC2
Names
DNA-directed RNA polymerase III subunit RPC2
RNA polymerase III subunit C2
DNA-directed RNA polymerase III subunit B
DNA-directed RNA polymerase III 127.6 kDa polypeptide
NP_001154180.1
NP_060552.4
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q23.3

Summary This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]. lac of sum
Disorder MIM:

614366

Disorder Html:





The following POLR3B gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the POLR3B gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu22699 NM_001160708 Homo sapiens polymerase (RNA) III (DNA directed) polypeptide B (POLR3B), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 16 Quote Price
OHu27279 NM_018082 Homo sapiens polymerase (RNA) III (DNA directed) polypeptide B (POLR3B), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 16 Quote Price

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu22699
Accession Version NM_001160708.1
Sequence Information ORF Nucleotide Sequence (Length: 3228bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product DNA-directed RNA polymerase III subunit RPC2 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB094040.1, AK122713.1, AC078992.23 and BC033724.2. Summary: This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]. Transcript Variant: This variant (2) differs in the 5' UTR and initiates translation at an in-frame downstream AUG, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK122713.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
ATGAAAGCCA ATGAAAAGGT TACAAGTGAC GCTGACCCTA TGTGGTACTT AAAATATCTT 
AATATCTATG TTGGGCTTCC TGATGTTGAA GAAAGCTTCA ATGTAACTAG ACCAGTGTCC
CCTCATGAGT GCCGTTTGAG AGACATGACA TACTCTGCCC CTATTACAGT GGATATTGAA
TATACCCGAG GCAGCCAGAG GATCATCCGC AATGCCTTAC CTATCGGCAG AATGCCCATA
ATGCTACGTA GTTCAAACTG TGTTCTTACA GGAAAAACGC CAGCAGAATT TGCCAAACTG
AACGAATGTC CCTTAGATCC AGGTGGCTAC TTCATTGTTA AAGGAGTAGA AAAAGTTATT
CTTATCCAAG AGCAGCTGTC TAAGAACAGG ATCATCGTGG AGGCTGATAG AAAAGGGGCT
GTTGGAGCTT CAGTTACCAG CTCTACCCAT GAGAAAAAAA GCAGAACCAA TATGGCTGTG
AAACAAGGAC GATTTTATTT GAGGCATAAT ACTTTGTCAG AAGATATACC CATTGTCATC
ATATTTAAGG CCATGGGTGT TGAGAGTGAC CAGGAAATTG TGCAGATGAT TGGAACAGAG
GAGCACGTGA TGGCTGCATT TGGGCCCAGT CTGGAAGAGT GCCAGAAAGC TCAGATTTTC
ACACAGATGC AGGCATTAAA ATATATAGGG AACAAAGTAA GAAGGCAAAG GATGTGGGGA
GGTGGACCAA AGAAAACCAA AATAGAAGAA GCAAGAGAGC TCCTGGCTTC CACCATTCTG
ACCCATGTCC CAGTTAAGGA ATTCAATTTC CGAGCCAAAT GTATCTATAC TGCAGTGATG
GTGCGAAGAG TTATTCTGGC CCAAGGAGAT AATAAAGTTG ACGACAGAGA TTATTATGGT
AACAAGCGAC TGGAATTGGC AGGACAGCTT TTATCTCTTC TTTTTGAAGA CTTGTTCAAA
AAATTTAATT CTGAAATGAA AAAGATTGCC GACCAGGTGA TTCCTAAGCA AAGAGCAGCC
CAGTTTGATG TTGTCAAACA CATGCGCCAA GACCAGATCA CCAATGGCAT GGTGAATGCT
ATTTCTACCG GAAATTGGTC TTTAAAGAGA TTTAAAATGG ACCGCCAGGG TGTAACCCAA
GTGCTGTCTC GCTTGTCATA TATATCCGCA CTGGGCATGA TGACAAGAAT CTCTTCCCAG
TTTGAAAAAA CGAGAAAAGT GAGTGGTCCT CGCTCCCTCC AGCCATCTCA GTGGGGAATG
CTGTGTCCTT CGGACACTCC TGAAGGAGAG GCATGTGGTT TGGTTAAAAA CTTGGCCCTT
ATGACACACA TCACAACTGA TATGGAAGAT GGACCCATTG TTAAATTAGC CAGTAACTTG
GGAGTAGAAG ATGTGAATTT ATTATGTGGG GAAGAGCTCT CTTACCCAAA TGTGTTTCTT
GTCTTTCTTA ATGGTAACAT CTTAGGTGTC ATTCGAGACC ACAAAAAGCT AGTGAATACA
TTTCGACTCA TGAGAAGAGC AGGATATATC AATGAATTTG TTTCCATCTC AACAAATCTT
ACAGATCGAT GTGTCTATAT TTCTTCTGAT GGGGGAAGGC TATGCAGACC CTACATAATT
GTCAAGAAAC AGAAGCCAGC AGTCACAAAT AAACATATGG AAGAGCTGGC CCAAGGGTAC
AGGAATTTTG AAGATTTCTT ACATGAGAGT CTGGTTGAAT ATTTAGATGT GAATGAAGAA
AATGATTGTA ACATTGCACT GTACGAACAC ACAATTAATA AAGACACCAC CCACTTGGAG
ATTGAACCCT TCACTCTTCT CGGCGTGTGT GCTGGACTTA TCCCATACCC TCACCATAAC
CAGTCACCGA GAAACACTTA TCAGTGTGCC ATGGGGAAAC AAGCCATGGG TACTATAGGA
TACAACCAGC GAAACAGAAT TGATACTCTC ATGTATCTAC TAGCATATCC ACAAAAACCC
ATGGTTAAGA CAAAAACCAT TGAATTGATA GAATTTGAGA AACTGCCAGC TGGACAGAAT
GCAACAGTTG CTGTGATGAG CTATAGTGGC TATGATATTG AAGATGCTCT TGTTTTAAAC
AAGGCCTCTT TAGACAGAGG CTTTGGGCGT TGCCTTGTAT ATAAAAATGC TAAATGTACG
TTGAAACGAT ACACCAATCA GACTTTTGAT AAAGTGATGG GGCCCATGTT GGATGCTGCT
ACAAGGAAAC CTATCTGGCG ACATGAAATC TTAGATGCAG ATGGTATTTG TTCTCCAGGT
GAGAAAGTAG AAAACAAACA AGTGCTTGTA AATAAGTCCA TGCCCACAGT GACTCAGATT
CCTTTGGAAG GAAGTAATGT ACCACAGCAA CCACAGTACA AAGATGTACC CATAACCTAC
AAAGGAGCAA CAGACTCATA TATTGAAAAA GTGATGATAT CTTCAAATGC TGAAGATGCT
TTTCTGATCA AAATGCTGCT GAGACAGACA AGGCGTCCAG AAATTGGAGA CAAATTCAGC
AGTCGTCATG GGCAAAAAGG TGTTTGTGGC TTGATCGTCC CCCAGGAAGA CATGCCATTT
TGTGATTCTG GCATCTGTCC GGACATCATC ATGAACCCAC ACGGCTTCCC ATCACGAATG
ACGGTGGGGA AGCTCATTGA GCTGCTGGCT GGCAAGGCCG GTGTGCTGGA CGGCAGATTC
CACTACGGCA CTGCGTTTGG AGGCAGTAAA GTGAAGGATG TGTGTGAGGA CCTCGTTCGC
CATGGTTATA ACTACTTGGG GAAAGACTAT GTTACATCCG GCATCACAGG TGAGCCCTTA
GAAGCATACA TCTATTTTGG CCCCGTGTAC TATCAGAAGC TGAAACACAT GGTGCTAGAT
AAAATGCATG CCCGGGCCCG GGGCCCACGA GCCGTCCTTA CCAGGCAACC CACTGAAGGA
CGGTCTCGTG ATGGTGGCTT GCGTCTCGGG GAAATGGAAC GTGACTGTTT AATCGGTTAT
GGAGCCAGTA TGCTTTTGCT AGAGAGACTA ATGATTTCAA GTGATGCCTT TGAGGTTGAT
GTCTGTGGGC AGTGTGGACT TCTGGGGTAT TCTGGCTGGT GCCATTACTG CAAGTCATCC
TGCCACGTGT CTTCCCTCCG TATTCCGTAT GCCTGCAAGC TGCTCTTCCA GGAACTACAG
TCTATGAACA TCATCCCCAG GTTAAAACTG TCCAAGTACA ATGAATGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001154180.1
CDS244..3471
Misc Feature(1)139..141(+)
Misc Feature(2)244..3450(+)
Misc Feature(3)292..3456(+)
Misc Feature(4)382..2529(+)
Misc Feature(5)1468..3450(+)
Misc Feature(6)1684..1869(+)
Misc Feature(7)1930..2052(+)
Misc Feature(8)2215..3081(+)
Misc Feature(9)2314..3048(+)
Misc Feature(10)2356..3072(+)
Exon (1)1..141
Gene:POLR3B
Gene Synonym:
Exon (2)142..174
Gene:POLR3B
Gene Synonym:
Exon (3)175..231
Gene:POLR3B
Gene Synonym:
Exon (4)232..296
Gene:POLR3B
Gene Synonym:
Exon (5)297..372
Gene:POLR3B
Gene Synonym:
Exon (6)373..473
Gene:POLR3B
Gene Synonym:
Exon (7)474..565
Gene:POLR3B
Gene Synonym:
Exon (8)566..683
Gene:POLR3B
Gene Synonym:
Exon (9)684..792
Gene:POLR3B
Gene Synonym:
Exon (10)793..915
Gene:POLR3B
Gene Synonym:
Exon (11)916..1035
Gene:POLR3B
Gene Synonym:
Exon (12)1036..1170
Gene:POLR3B
Gene Synonym:
Exon (13)1171..1332
Gene:POLR3B
Gene Synonym:
Exon (14)1333..1533
Gene:POLR3B
Gene Synonym:
Exon (15)1534..1696
Gene:POLR3B
Gene Synonym:
Exon (16)1697..1850
Gene:POLR3B
Gene Synonym:
Exon (17)1851..1925
Gene:POLR3B
Gene Synonym:
Exon (18)1926..2024
Gene:POLR3B
Gene Synonym:
Exon (19)2025..2152
Gene:POLR3B
Gene Synonym:
Exon (20)2153..2362
Gene:POLR3B
Gene Synonym:
Exon (21)2363..2521
Gene:POLR3B
Gene Synonym:
Exon (22)2522..2639
Gene:POLR3B
Gene Synonym:
Exon (23)2640..2782
Gene:POLR3B
Gene Synonym:
Exon (24)2783..2886
Gene:POLR3B
Gene Synonym:
Exon (25)2887..3053
Gene:POLR3B
Gene Synonym:
Exon (26)3054..3167
Gene:POLR3B
Gene Synonym:
Exon (27)3168..3341
Gene:POLR3B
Gene Synonym:
Exon (28)3342..4120
Gene:POLR3B
Gene Synonym:
Translation
Position Chain Variation Link
9 9 a, g dbSNP:374177704
12 12 c, t dbSNP:769230776
16 16 c, t dbSNP:17285274
21 21 -, t dbSNP:753621178
30 30 a, g dbSNP:575533516
40 40 g, t dbSNP:147800352
51 51 -, agtga dbSNP:762498968
52 52 -, agtga dbSNP:139244819
54 54 -, tgaag dbSNP:780018048
54 54 g, t dbSNP:199971708
56 56 a, g dbSNP:532451472
62 62 a, g dbSNP:545999873
65 65 c, t dbSNP:562636662
86 86 g, t dbSNP:531519010
90 90 c, g dbSNP:548530540
101 101 a, g dbSNP:568353995
106 106 a, g dbSNP:141219725
136 136 c, g dbSNP:547033135
138 138 a, g dbSNP:570549842
154 154 c, g dbSNP:779537305
157 157 c, t dbSNP:778337028
175 175 a, g dbSNP:763829196
177 177 a, g dbSNP:548719279
187 187 a, g dbSNP:753126070
195 195 a, g dbSNP:756485164
199 199 a, g dbSNP:764300320
201 201 a, g dbSNP:754400950
234 234 -, aaa dbSNP:745721628
234 234 a, g dbSNP:748135287
241 241 a, t dbSNP:568682674
243 243 -, aatg dbSNP:771959481
249 249 a, g dbSNP:774453914
254 254 a, g dbSNP:527953383
262 262 c, g dbSNP:767784504
267 267 a, g dbSNP:775696277
276 276 a, t dbSNP:760770690
277 277 a, g dbSNP:764541119
279 279 c, t dbSNP:368827027
282 282 a, t dbSNP:757826726
283 283 a, g dbSNP:765662843
299 299 a, g dbSNP:376800357
313 313 a, g dbSNP:777122841
318 318 c, g dbSNP:762075246
326 326 a, t dbSNP:765643493
327 327 c, t dbSNP:750967094
343 343 a, g dbSNP:763510140
344 344 a, g dbSNP:369375037
345 345 -, t dbSNP:747216457
351 351 c, t dbSNP:766007096
361 361 -, c dbSNP:768881912
363 363 c, g dbSNP:767779527
377 377 g, t dbSNP:780148992
382 382 a, g dbSNP:747058861
385 385 a, g dbSNP:369178623
393 393 a, g dbSNP:752743933
398 398 c, g dbSNP:776736710
400 400 g, t dbSNP:762031872
406 406 a, g dbSNP:770310005
410 410 c, t dbSNP:773657828
411 411 a, c, g dbSNP:372178891
430 430 c, t dbSNP:751146923
440 440 a, g dbSNP:758954024
451 451 c, t dbSNP:369609747
453 453 c, t dbSNP:752324047
468 468 c, t dbSNP:147328031
469 469 a, g dbSNP:777595105
474 474 a, g dbSNP:750363471
491 491 a, g dbSNP:758303166
495 495 c, t dbSNP:781175232
501 501 c, g dbSNP:748225333
503 503 a, g dbSNP:139443783
512 512 c, g dbSNP:373170094
521 521 c, g, t dbSNP:145075371
522 522 a, g dbSNP:376395471
525 525 a, g dbSNP:771426214
538 538 a, g dbSNP:369977235
539 539 a, c dbSNP:746411185
542 542 c, t dbSNP:772602443
546 546 c, t dbSNP:771392826
547 547 a, c, g dbSNP:749479456
553 553 c, g dbSNP:373099408
584 584 a, g dbSNP:747452509
596 596 a, g dbSNP:768190013
606 606 c, t dbSNP:113468238
610 610 c, t dbSNP:776074515
612 612 a, c dbSNP:201182565
615 615 a, g dbSNP:761499674
630 630 c, t dbSNP:769452308
639 639 c, t dbSNP:772944396
640 640 a, g, t dbSNP:545766074
654 654 a, g dbSNP:766028971
655 655 a, g dbSNP:751544859
657 657 a, t dbSNP:759507297
663 663 c, t dbSNP:764291006
665 665 c, t dbSNP:753938916
680 680 c, t dbSNP:147582475
704 704 -, g dbSNP:761939876
721 721 g, t dbSNP:371141763
722 722 g, t dbSNP:79802610
733 733 c, g, t dbSNP:767558518
745 745 a, g dbSNP:761968415
762 762 a, c dbSNP:571717073
770 770 c, t dbSNP:750692716
775 775 a, g dbSNP:758503582
780 780 a, c dbSNP:201300488
781 781 a, t dbSNP:199892569
790 790 a, c dbSNP:751885179
800 800 g, t dbSNP:199782156
802 802 a, g dbSNP:751975109
805 805 a, g dbSNP:755346691
810 810 a, t dbSNP:767801107
831 831 a, g dbSNP:753277030
832 832 a, g dbSNP:140433171
840 840 a, g, t dbSNP:201822852
842 842 a, c dbSNP:117911920
845 845 a, g dbSNP:778723427
850 850 a, g dbSNP:201440861
860 860 c, t dbSNP:772026926
865 865 a, g dbSNP:775102202
888 888 c, g dbSNP:747019905
889 889 a, g dbSNP:768451113
898 898 a, t dbSNP:773404949
904 904 a, t dbSNP:368961144
911 911 c, t dbSNP:766385955
929 929 c, t dbSNP:771028048
933 933 a, g dbSNP:376166938
952 952 a, g dbSNP:774363956
955 955 a, g dbSNP:759803156
961 961 a, g dbSNP:772152947
968 968 a, g dbSNP:775981204
992 992 a, c dbSNP:193156019
994 994 a, g dbSNP:369488769
1013 1013 c, t dbSNP:373723723
1018 1018 a, g dbSNP:376426432
1029 1029 -, ccag dbSNP:367995157
1035 1035 a, g dbSNP:764892043
1040 1040 a, g dbSNP:201270085
1042 1042 g, t dbSNP:756111014
1044 1044 a, g dbSNP:145542203
1048 1048 a, t dbSNP:200042871
1054 1054 c, t dbSNP:758437925
1072 1072 a, c dbSNP:780131061
1078 1078 g, t dbSNP:747242779
1080 1080 c, g dbSNP:768888177
1087 1087 c, t dbSNP:148879912
1088 1088 a, g dbSNP:565545064
1093 1093 a, g dbSNP:370376465
1106 1106 a, g dbSNP:748506543
1112 1112 a, t dbSNP:770230205
1125 1125 c, t dbSNP:143599158
1126 1126 a, g dbSNP:763479999
1128 1128 -, a dbSNP:766754661
1150 1150 a, c dbSNP:765830807
1158 1158 a, g dbSNP:757801078
1171 1171 c, t dbSNP:201079775
1171 1171 c, t dbSNP:386457647
1175 1175 -, tatctcttc dbSNP:748218020
1176 1176 a, t dbSNP:763836079
1178 1178 c, t dbSNP:753739949
1180 1180 c, t dbSNP:757194712
1182 1182 c, t dbSNP:141885523
1183 1183 c, g, t dbSNP:568917673
1200 1200 a, c dbSNP:755209771
1216 1216 a, g dbSNP:781583092
1226 1226 a, c dbSNP:748318494
1233 1233 c, t dbSNP:770316358
1234 1234 a, g dbSNP:773665687
1237 1237 c, t dbSNP:548827190
1257 1257 a, g dbSNP:200803445
1266 1266 a, g dbSNP:773801173
1285 1285 a, g dbSNP:759073982
1299 1299 c, g dbSNP:375986407
1302 1302 c, t dbSNP:775154232
1306 1306 a, g dbSNP:760269619
1307 1307 a, g dbSNP:763924026
1308 1308 c, t dbSNP:753635412
1313 1313 c, t dbSNP:199504211
1324 1324 a, g dbSNP:768889169
1329 1329 a, c, t dbSNP:371496625
1332 1332 a, c, t dbSNP:367607316
1338 1338 c, t dbSNP:756473072
1358 1358 a, g dbSNP:778044327
1377 1377 a, g dbSNP:761371993
1380 1380 c, g dbSNP:551945764
1389 1389 a, g dbSNP:753949347
1394 1394 a, g, t dbSNP:201153027
1401 1401 a, g dbSNP:145020083
1405 1405 a, g dbSNP:772535359
1410 1410 c, t dbSNP:545561868
1411 1411 a, g, t dbSNP:746506474
1413 1413 a, g dbSNP:138822077
1416 1416 a, g dbSNP:193106695
1434 1434 a, c dbSNP:565387901
1437 1437 -, ttcccag dbSNP:773229494
1437 1437 c, t dbSNP:140483599
1447 1447 g, t dbSNP:370169112
1455 1455 a, g dbSNP:766417611
1470 1470 a, t dbSNP:74390456
1500 1500 a, g dbSNP:760850969
1514 1514 c, t dbSNP:747108240
1515 1515 a, g dbSNP:754111056
1547 1547 c, t dbSNP:764283322
1557 1557 a, g dbSNP:776540625
1577 1577 a, c dbSNP:267608683
1585 1585 a, g dbSNP:762160281
1586 1586 c, t dbSNP:765361070
1594 1594 -, g dbSNP:750294348
1601 1601 -, t dbSNP:763485186
1602 1602 -, t dbSNP:267608684
1621 1621 c, g, t dbSNP:750584323
1637 1637 a, t dbSNP:138249161
1647 1647 a, g dbSNP:537025390
1649 1649 g, t dbSNP:755422501
1650 1650 c, t dbSNP:780797276
1661 1661 c, t dbSNP:747610772
1671 1671 a, g dbSNP:200983703
1672 1672 a, g dbSNP:755854514
1689 1689 c, t dbSNP:777583980
1694 1694 a, g dbSNP:748882857
1699 1699 a, g dbSNP:755584491
1717 1717 c, t dbSNP:267608688
1721 1721 a, c dbSNP:777378373
1731 1731 a, g dbSNP:753592392
1732 1732 c, t dbSNP:756939086
1734 1734 a, g dbSNP:546320667
1742 1742 c, t dbSNP:745635075
1747 1747 c, t dbSNP:771838685
1748 1748 a, g dbSNP:779858391
1753 1753 a, g dbSNP:746920953
1758 1758 a, c, g dbSNP:200865877
1770 1770 c, t dbSNP:763207067
1771 1771 a, g dbSNP:35983209
1775 1775 a, g dbSNP:551949170
1776 1776 c, t dbSNP:17038450
1789 1789 a, g dbSNP:200126234
1792 1792 c, t dbSNP:767857927
1806 1806 a, g dbSNP:753176222
1810 1810 a, c, t dbSNP:576127663
1812 1812 a, g dbSNP:537703445
1820 1820 a, g dbSNP:753393949
1832 1832 a, t dbSNP:757026963
1845 1845 a, t dbSNP:201223367
1858 1858 a, g dbSNP:147324507
1864 1864 a, g dbSNP:764797827
1873 1873 c, g dbSNP:750061760
1888 1888 a, g dbSNP:758043469
1891 1891 a, g dbSNP:766131152
1900 1900 a, g dbSNP:751369777
1903 1903 c, g dbSNP:754968519
1936 1936 g, t dbSNP:747184457
1942 1942 c, t dbSNP:139376910
1969 1969 a, g dbSNP:781671613
1983 1983 a, c dbSNP:748702792
1992 1992 c, t dbSNP:770333846
2007 2007 a, c, t dbSNP:143400457
2008 2008 a, g dbSNP:755658678
2013 2013 a, c dbSNP:770284337
2016 2016 -, aatt dbSNP:761276079
2016 2016 a, g dbSNP:774024453
2021 2021 a, g dbSNP:527638833
2027 2027 a, g, t dbSNP:144161033
2030 2030 c, t dbSNP:200782069
2036 2036 a, t dbSNP:763755551
2040 2040 a, g dbSNP:148613297
2043 2043 a, g dbSNP:201895619
2045 2045 c, t dbSNP:142094821
2049 2049 a, g dbSNP:751682027
2057 2057 c, t dbSNP:755312623
2064 2064 c, t dbSNP:767867634
2067 2067 c, t dbSNP:369468138
2068 2068 a, g dbSNP:756536922
2070 2070 a, c, g dbSNP:777951679
2088 2088 a, g dbSNP:757676950
2109 2109 a, g dbSNP:778462763
2112 2112 a, g dbSNP:372517855
2121 2121 c, t dbSNP:376791688
2124 2124 c, g, t dbSNP:10861607
2143 2143 -, c dbSNP:764859439
2173 2173 c, t dbSNP:201401034
2194 2194 a, t dbSNP:773318236
2205 2205 a, g dbSNP:139146614
2215 2215 -, a dbSNP:758413153
2221 2221 c, t dbSNP:772327533
2224 2224 a, g dbSNP:775402995
2227 2227 a, g dbSNP:761026189
2230 2230 a, t dbSNP:374359855
2239 2239 a, c dbSNP:754023038
2242 2242 a, g dbSNP:762195295
2248 2248 c, g, t dbSNP:375960295
2249 2249 c, t dbSNP:758867273
2252 2252 c, t dbSNP:748464579
2277 2277 a, t dbSNP:200497639
2287 2287 a, g dbSNP:17038460
2289 2289 a, g dbSNP:754450206
2294 2294 c, t dbSNP:528154460
2299 2299 a, g dbSNP:747766146
2300 2300 c, t dbSNP:769736904
2323 2323 g, t dbSNP:201716779
2328 2328 c, t dbSNP:199743272
2342 2342 a, g dbSNP:749277976
2347 2347 a, g, t dbSNP:146513209
2363 2363 g, t dbSNP:770703901
2371 2371 c, t dbSNP:371453512
2372 2372 a, g dbSNP:267608687
2376 2376 c, t dbSNP:768665790
2378 2378 a, t dbSNP:748805276
2380 2380 a, g dbSNP:776660787
2381 2381 c, t dbSNP:748432049
2402 2402 c, t dbSNP:375480706
2403 2403 a, g dbSNP:150800622
2411 2411 a, g dbSNP:538577233
2420 2420 a, c dbSNP:766728879
2423 2423 a, t dbSNP:774746326
2431 2431 c, g dbSNP:143507316
2448 2448 c, t dbSNP:766980809
2455 2455 a, g dbSNP:368613977
2456 2456 a, t dbSNP:755889644
2463 2463 c, t dbSNP:763853811
2469 2469 a, g dbSNP:753499989
2476 2476 a, g dbSNP:372387469
2483 2483 a, g dbSNP:146772688
2490 2490 a, g dbSNP:377149913
2492 2492 c, t dbSNP:573261309
2502 2502 a, c dbSNP:552412004
2505 2505 c, t dbSNP:758347944
2528 2528 a, c dbSNP:777811614
2532 2532 a, g dbSNP:34681274
2551 2551 c, g, t dbSNP:749516917
2552 2552 c, t dbSNP:779203620
2555 2555 a, g dbSNP:200502989
2562 2562 c, t dbSNP:764111608
2566 2566 c, g dbSNP:772499805
2569 2569 a, g dbSNP:776161810
2570 2570 c, t dbSNP:148931372
2589 2589 a, g dbSNP:768321161
2598 2598 -, aatgtac dbSNP:748423263
2599 2599 a, c dbSNP:776199937
2600 2600 a, g dbSNP:547835696
2601 2601 c, t dbSNP:764952250
2604 2604 a, g dbSNP:749973787
2616 2616 a, g dbSNP:752119970
2617 2617 c, t dbSNP:766115864
2634 2634 c, t dbSNP:751549093
2637 2637 a, g dbSNP:754879484
2639 2639 c, t dbSNP:777896021
2642 2642 a, g dbSNP:113715233
2645 2645 a, g dbSNP:766203968
2665 2665 a, g dbSNP:751352752
2677 2677 a, g dbSNP:759527548
2684 2684 c, g dbSNP:369017509
2697 2697 a, c dbSNP:752513905
2701 2701 a, g dbSNP:201627534
2710 2710 -, at dbSNP:777831969
2717 2717 c, t dbSNP:757392794
2737 2737 c, t dbSNP:778812401
2738 2738 a, g dbSNP:750694928
2747 2747 c, t dbSNP:758685804
2750 2750 g, t dbSNP:780618644
2755 2755 a, t dbSNP:267608685
2762 2762 a, g dbSNP:143703583
2767 2767 c, t dbSNP:755326914
2778 2778 a, g dbSNP:781737270
2796 2796 g, t dbSNP:201781254
2797 2797 a, g, t dbSNP:569069911
2799 2799 c, t dbSNP:538183170
2800 2800 a, g dbSNP:770365711
2807 2807 a, c dbSNP:774026760
2820 2820 a, g dbSNP:745477859
2828 2828 a, t dbSNP:771954727
2838 2838 c, g dbSNP:554886814
2843 2843 c, t dbSNP:775141057
2844 2844 a, g dbSNP:769294366
2847 2847 c, g dbSNP:267608689
2858 2858 a, c dbSNP:763947981
2860 2860 c, g dbSNP:373101426
2865 2865 c, t dbSNP:141030994
2878 2878 c, t dbSNP:763154774
2889 2889 g, t dbSNP:139255984
2892 2892 a, g dbSNP:757733299
2904 2904 a, g dbSNP:778450287
2910 2910 a, g dbSNP:749912429
2911 2911 a, g, t dbSNP:757853544
2912 2912 c, t dbSNP:779604405
2914 2914 a, g dbSNP:746622682
2916 2916 c, t dbSNP:373826323
2917 2917 a, c dbSNP:781100960
2922 2922 c, t dbSNP:748165243
2923 2923 a, g dbSNP:201465114
2924 2924 a, g dbSNP:773226013
2929 2929 c, t dbSNP:759539441
2933 2933 a, g dbSNP:553733271
2934 2934 c, t dbSNP:143284189
2942 2942 g, t dbSNP:368515122
2944 2944 c, t dbSNP:764486483
2946 2946 c, t dbSNP:148708579
2948 2948 a, g dbSNP:762105430
2953 2953 a, c dbSNP:765733223
2957 2957 c, t dbSNP:750899096
2968 2968 a, c dbSNP:200865021
2971 2971 a, g dbSNP:765891224
2974 2974 a, g dbSNP:200477676
2997 2997 -, gagg dbSNP:759862082
2997 2997 c, t dbSNP:754671920
2998 2998 a, g dbSNP:199545845
3001 3001 c, t dbSNP:747972980
3002 3002 a, g dbSNP:117293015
3005 3005 a, g dbSNP:777603547
3007 3007 a, g dbSNP:199865077
3012 3012 c, t dbSNP:372059822
3013 3013 a, g dbSNP:368213717
3029 3029 a, c dbSNP:138378720
3031 3031 -, ta dbSNP:772463810
3032 3032 a, g dbSNP:149257714
3037 3037 a, g dbSNP:372036820
3042 3042 c, t dbSNP:747265286
3045 3045 a, c dbSNP:768877018
3057 3057 a, g dbSNP:144485339
3061 3061 g, t dbSNP:759833434
3063 3063 a, g dbSNP:753657104
3065 3065 a, g dbSNP:765573891
3067 3067 a, g dbSNP:756931770
3069 3069 a, g dbSNP:778937914
3077 3077 a, g dbSNP:368953286
3081 3081 c, t dbSNP:567765509
3084 3084 c, t dbSNP:148438504
3087 3087 c, t dbSNP:373346251
3088 3088 a, g, t dbSNP:375472185
3104 3104 c, t dbSNP:749670593
3118 3118 c, t dbSNP:771161167
3120 3120 a, g dbSNP:144051136
3135 3135 a, c, t dbSNP:145991322
3141 3141 c, t dbSNP:369730210
3151 3151 c, t dbSNP:775137613
3152 3152 a, g dbSNP:758183544
3157 3157 a, g dbSNP:760305780
3168 3168 a, g dbSNP:746448456
3171 3171 a, g dbSNP:370631015
3174 3174 c, t dbSNP:778281040
3177 3177 c, t dbSNP:760261511
3195 3195 g, t dbSNP:373822144
3210 3210 c, t dbSNP:776391361
3211 3211 a, g dbSNP:761337432
3213 3213 c, g dbSNP:568662073
3215 3215 a, g dbSNP:79171601
3216 3216 a, g dbSNP:772975950
3231 3231 c, t dbSNP:762678539
3237 3237 c, t dbSNP:139920513
3242 3242 a, g dbSNP:751459271
3253 3253 a, g dbSNP:756242647
3255 3255 a, g dbSNP:201777932
3264 3264 a, g dbSNP:143441199
3267 3267 a, g dbSNP:745914949
3281 3281 a, c dbSNP:779482867
3291 3291 c, t dbSNP:746252168
3302 3302 a, g dbSNP:758792141
3306 3306 c, t dbSNP:188914862
3309 3309 c, t dbSNP:550453071
3322 3322 c, t dbSNP:370363631
3327 3327 c, g dbSNP:747449371
3338 3338 g, t dbSNP:770376797
3342 3342 a, g dbSNP:768612175
3360 3360 a, g dbSNP:759579343
3371 3371 c, t dbSNP:771921629
3382 3382 c, t dbSNP:575865538
3383 3383 a, g dbSNP:762004021
3386 3386 c, t dbSNP:765382317
3390 3390 a, g dbSNP:113017214
3393 3393 c, t dbSNP:763259986
3401 3401 a, g dbSNP:766823201
3407 3407 c, t dbSNP:751882154
3417 3417 a, g dbSNP:151232276
3423 3423 g, t dbSNP:781580610
3425 3425 c, t dbSNP:753201056
3427 3427 a, g dbSNP:755670879
3439 3439 c, g dbSNP:777235804
3443 3443 c, g dbSNP:749008585
3444 3444 a, g dbSNP:770560138
3459 3459 c, g dbSNP:201527706
3464 3464 a, g dbSNP:200967068
3465 3465 c, t dbSNP:13561
3466 3466 a, g dbSNP:775335616
3472 3472 c, g dbSNP:149990218
3476 3476 a, g dbSNP:373363499
3485 3485 a, g dbSNP:773410138
3486 3486 a, g, t dbSNP:763068456
3490 3490 c, t dbSNP:751764949
3495 3495 a, g dbSNP:759841627
3506 3506 a, g dbSNP:767902490
3509 3509 a, c, g dbSNP:377492248
3510 3510 a, c dbSNP:756609861
3517 3517 a, g dbSNP:371809211
3521 3521 c, t dbSNP:777325577
3522 3522 a, g dbSNP:189041433
3531 3531 a, g dbSNP:560425343
3547 3547 c, t dbSNP:754054633
3569 3569 c, t dbSNP:532224514
3574 3574 c, t dbSNP:545951495
3580 3580 c, t dbSNP:759691487
3582 3582 c, g dbSNP:562644313
3596 3596 -, a dbSNP:200331241
3606 3606 a, t dbSNP:531592970
3634 3634 a, t dbSNP:765299949
3650 3650 a, t dbSNP:376396754
3666 3666 c, t dbSNP:547822703
3688 3688 a, g dbSNP:752808674
3709 3709 c, t dbSNP:149535796
3719 3719 g, t dbSNP:181864410
3723 3723 g, t dbSNP:778314251
3743 3743 c, t dbSNP:547073426
3785 3785 g, t dbSNP:570177691
3788 3788 a, c dbSNP:143084704
3813 3813 c, g dbSNP:186425739
3818 3818 a, g dbSNP:2288266
3843 3843 a, g dbSNP:557970332
3854 3854 c, t dbSNP:191071027
3897 3897 c, t dbSNP:781241574
3912 3912 c, t dbSNP:555034182
3913 3913 a, g dbSNP:574873455
3926 3926 c, t dbSNP:540600406
3927 3927 a, g dbSNP:554332080
3963 3963 a, t dbSNP:780838654
3967 3967 c, g dbSNP:745461447
3992 3992 g, t dbSNP:577222793
4015 4015 a, g dbSNP:545689984
4027 4027 -, a dbSNP:3217286
4030 4030 a, c dbSNP:769435306
4036 4036 a, g dbSNP:55715506
4053 4053 c, g dbSNP:75217257
4058 4058 c, g dbSNP:576237770
4073 4073 c, t dbSNP:541699640

Target ORF information:

RefSeq Version NM_001160708
Organism Homo sapiens (human)
Definition Homo sapiens polymerase (RNA) III (DNA directed) polypeptide B (POLR3B), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001160708

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
ATGAAAGCCA ATGAAAAGGT TACAAGTGAC GCTGACCCTA TGTGGTACTT AAAATATCTT 
AATATCTATG TTGGGCTTCC TGATGTTGAA GAAAGCTTCA ATGTAACTAG ACCAGTGTCC
CCTCATGAGT GCCGTTTGAG AGACATGACA TACTCTGCCC CTATTACAGT GGATATTGAA
TATACCCGAG GCAGCCAGAG GATCATCCGC AATGCCTTAC CTATCGGCAG AATGCCCATA
ATGCTACGTA GTTCAAACTG TGTTCTTACA GGAAAAACGC CAGCAGAATT TGCCAAACTG
AACGAATGTC CCTTAGATCC AGGTGGCTAC TTCATTGTTA AAGGAGTAGA AAAAGTTATT
CTTATCCAAG AGCAGCTGTC TAAGAACAGG ATCATCGTGG AGGCTGATAG AAAAGGGGCT
GTTGGAGCTT CAGTTACCAG CTCTACCCAT GAGAAAAAAA GCAGAACCAA TATGGCTGTG
AAACAAGGAC GATTTTATTT GAGGCATAAT ACTTTGTCAG AAGATATACC CATTGTCATC
ATATTTAAGG CCATGGGTGT TGAGAGTGAC CAGGAAATTG TGCAGATGAT TGGAACAGAG
GAGCACGTGA TGGCTGCATT TGGGCCCAGT CTGGAAGAGT GCCAGAAAGC TCAGATTTTC
ACACAGATGC AGGCATTAAA ATATATAGGG AACAAAGTAA GAAGGCAAAG GATGTGGGGA
GGTGGACCAA AGAAAACCAA AATAGAAGAA GCAAGAGAGC TCCTGGCTTC CACCATTCTG
ACCCATGTCC CAGTTAAGGA ATTCAATTTC CGAGCCAAAT GTATCTATAC TGCAGTGATG
GTGCGAAGAG TTATTCTGGC CCAAGGAGAT AATAAAGTTG ACGACAGAGA TTATTATGGT
AACAAGCGAC TGGAATTGGC AGGACAGCTT TTATCTCTTC TTTTTGAAGA CTTGTTCAAA
AAATTTAATT CTGAAATGAA AAAGATTGCC GACCAGGTGA TTCCTAAGCA AAGAGCAGCC
CAGTTTGATG TTGTCAAACA CATGCGCCAA GACCAGATCA CCAATGGCAT GGTGAATGCT
ATTTCTACCG GAAATTGGTC TTTAAAGAGA TTTAAAATGG ACCGCCAGGG TGTAACCCAA
GTGCTGTCTC GCTTGTCATA TATATCCGCA CTGGGCATGA TGACAAGAAT CTCTTCCCAG
TTTGAAAAAA CGAGAAAAGT GAGTGGTCCT CGCTCCCTCC AGCCATCTCA GTGGGGAATG
CTGTGTCCTT CGGACACTCC TGAAGGAGAG GCATGTGGTT TGGTTAAAAA CTTGGCCCTT
ATGACACACA TCACAACTGA TATGGAAGAT GGACCCATTG TTAAATTAGC CAGTAACTTG
GGAGTAGAAG ATGTGAATTT ATTATGTGGG GAAGAGCTCT CTTACCCAAA TGTGTTTCTT
GTCTTTCTTA ATGGTAACAT CTTAGGTGTC ATTCGAGACC ACAAAAAGCT AGTGAATACA
TTTCGACTCA TGAGAAGAGC AGGATATATC AATGAATTTG TTTCCATCTC AACAAATCTT
ACAGATCGAT GTGTCTATAT TTCTTCTGAT GGGGGAAGGC TATGCAGACC CTACATAATT
GTCAAGAAAC AGAAGCCAGC AGTCACAAAT AAACATATGG AAGAGCTGGC CCAAGGGTAC
AGGAATTTTG AAGATTTCTT ACATGAGAGT CTGGTTGAAT ATTTAGATGT GAATGAAGAA
AATGATTGTA ACATTGCACT GTACGAACAC ACAATTAATA AAGACACCAC CCACTTGGAG
ATTGAACCCT TCACTCTTCT CGGCGTGTGT GCTGGACTTA TCCCATACCC TCACCATAAC
CAGTCACCGA GAAACACTTA TCAGTGTGCC ATGGGGAAAC AAGCCATGGG TACTATAGGA
TACAACCAGC GAAACAGAAT TGATACTCTC ATGTATCTAC TAGCATATCC ACAAAAACCC
ATGGTTAAGA CAAAAACCAT TGAATTGATA GAATTTGAGA AACTGCCAGC TGGACAGAAT
GCAACAGTTG CTGTGATGAG CTATAGTGGC TATGATATTG AAGATGCTCT TGTTTTAAAC
AAGGCCTCTT TAGACAGAGG CTTTGGGCGT TGCCTTGTAT ATAAAAATGC TAAATGTACG
TTGAAACGAT ACACCAATCA GACTTTTGAT AAAGTGATGG GGCCCATGTT GGATGCTGCT
ACAAGGAAAC CTATCTGGCG ACATGAAATC TTAGATGCAG ATGGTATTTG TTCTCCAGGT
GAGAAAGTAG AAAACAAACA AGTGCTTGTA AATAAGTCCA TGCCCACAGT GACTCAGATT
CCTTTGGAAG GAAGTAATGT ACCACAGCAA CCACAGTACA AAGATGTACC CATAACCTAC
AAAGGAGCAA CAGACTCATA TATTGAAAAA GTGATGATAT CTTCAAATGC TGAAGATGCT
TTTCTGATCA AAATGCTGCT GAGACAGACA AGGCGTCCAG AAATTGGAGA CAAATTCAGC
AGTCGTCATG GGCAAAAAGG TGTTTGTGGC TTGATCGTCC CCCAGGAAGA CATGCCATTT
TGTGATTCTG GCATCTGTCC GGACATCATC ATGAACCCAC ACGGCTTCCC ATCACGAATG
ACGGTGGGGA AGCTCATTGA GCTGCTGGCT GGCAAGGCCG GTGTGCTGGA CGGCAGATTC
CACTACGGCA CTGCGTTTGG AGGCAGTAAA GTGAAGGATG TGTGTGAGGA CCTCGTTCGC
CATGGTTATA ACTACTTGGG GAAAGACTAT GTTACATCCG GCATCACAGG TGAGCCCTTA
GAAGCATACA TCTATTTTGG CCCCGTGTAC TATCAGAAGC TGAAACACAT GGTGCTAGAT
AAAATGCATG CCCGGGCCCG GGGCCCACGA GCCGTCCTTA CCAGGCAACC CACTGAAGGA
CGGTCTCGTG ATGGTGGCTT GCGTCTCGGG GAAATGGAAC GTGACTGTTT AATCGGTTAT
GGAGCCAGTA TGCTTTTGCT AGAGAGACTA ATGATTTCAA GTGATGCCTT TGAGGTTGAT
GTCTGTGGGC AGTGTGGACT TCTGGGGTAT TCTGGCTGGT GCCATTACTG CAAGTCATCC
TGCCACGTGT CTTCCCTCCG TATTCCGTAT GCCTGCAAGC TGCTCTTCCA GGAACTACAG
TCTATGAACA TCATCCCCAG GTTAAAACTG TCCAAGTACA ATGAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27279
Accession Version NM_018082.5
Sequence Information ORF Nucleotide Sequence (Length: 3402bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product DNA-directed RNA polymerase III subunit RPC2 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA236776.1, BX537447.1 and BC033724.2. This sequence is a reference standard in the RefSeqGene project. On Jun 5, 2009 this sequence version replaced gi:142370957. Summary: This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX537447.1, AY092084.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
ATGGACGTGC TAGCGGAGGA GTTTGGGAAC CTGACTCCGG AGCAGCTGGC GGCGCCGATC 
CCGACTGTAG AGGAAAAATG GAGGCTGCTT CCAGCATTTT TAAAGGTGAA AGGCCTTGTG
AAACAGCATA TAGATTCATT TAACTATTTC ATTAATGTAG AGATAAAGAA GATAATGAAA
GCCAATGAAA AGGTTACAAG TGACGCTGAC CCTATGTGGT ACTTAAAATA TCTTAATATC
TATGTTGGGC TTCCTGATGT TGAAGAAAGC TTCAATGTAA CTAGACCAGT GTCCCCTCAT
GAGTGCCGTT TGAGAGACAT GACATACTCT GCCCCTATTA CAGTGGATAT TGAATATACC
CGAGGCAGCC AGAGGATCAT CCGCAATGCC TTACCTATCG GCAGAATGCC CATAATGCTA
CGTAGTTCAA ACTGTGTTCT TACAGGAAAA ACGCCAGCAG AATTTGCCAA ACTGAACGAA
TGTCCCTTAG ATCCAGGTGG CTACTTCATT GTTAAAGGAG TAGAAAAAGT TATTCTTATC
CAAGAGCAGC TGTCTAAGAA CAGGATCATC GTGGAGGCTG ATAGAAAAGG GGCTGTTGGA
GCTTCAGTTA CCAGCTCTAC CCATGAGAAA AAAAGCAGAA CCAATATGGC TGTGAAACAA
GGACGATTTT ATTTGAGGCA TAATACTTTG TCAGAAGATA TACCCATTGT CATCATATTT
AAGGCCATGG GTGTTGAGAG TGACCAGGAA ATTGTGCAGA TGATTGGAAC AGAGGAGCAC
GTGATGGCTG CATTTGGGCC CAGTCTGGAA GAGTGCCAGA AAGCTCAGAT TTTCACACAG
ATGCAGGCAT TAAAATATAT AGGGAACAAA GTAAGAAGGC AAAGGATGTG GGGAGGTGGA
CCAAAGAAAA CCAAAATAGA AGAAGCAAGA GAGCTCCTGG CTTCCACCAT TCTGACCCAT
GTCCCAGTTA AGGAATTCAA TTTCCGAGCC AAATGTATCT ATACTGCAGT GATGGTGCGA
AGAGTTATTC TGGCCCAAGG AGATAATAAA GTTGACGACA GAGATTATTA TGGTAACAAG
CGACTGGAAT TGGCAGGACA GCTTTTATCT CTTCTTTTTG AAGACTTGTT CAAAAAATTT
AATTCTGAAA TGAAAAAGAT TGCCGACCAG GTGATTCCTA AGCAAAGAGC AGCCCAGTTT
GATGTTGTCA AACACATGCG CCAAGACCAG ATCACCAATG GCATGGTGAA TGCTATTTCT
ACCGGAAATT GGTCTTTAAA GAGATTTAAA ATGGACCGCC AGGGTGTAAC CCAAGTGCTG
TCTCGCTTGT CATATATATC CGCACTGGGC ATGATGACAA GAATCTCTTC CCAGTTTGAA
AAAACGAGAA AAGTGAGTGG TCCTCGCTCC CTCCAGCCAT CTCAGTGGGG AATGCTGTGT
CCTTCGGACA CTCCTGAAGG AGAGGCATGT GGTTTGGTTA AAAACTTGGC CCTTATGACA
CACATCACAA CTGATATGGA AGATGGACCC ATTGTTAAAT TAGCCAGTAA CTTGGGAGTA
GAAGATGTGA ATTTATTATG TGGGGAAGAG CTCTCTTACC CAAATGTGTT TCTTGTCTTT
CTTAATGGTA ACATCTTAGG TGTCATTCGA GACCACAAAA AGCTAGTGAA TACATTTCGA
CTCATGAGAA GAGCAGGATA TATCAATGAA TTTGTTTCCA TCTCAACAAA TCTTACAGAT
CGATGTGTCT ATATTTCTTC TGATGGGGGA AGGCTATGCA GACCCTACAT AATTGTCAAG
AAACAGAAGC CAGCAGTCAC AAATAAACAT ATGGAAGAGC TGGCCCAAGG GTACAGGAAT
TTTGAAGATT TCTTACATGA GAGTCTGGTT GAATATTTAG ATGTGAATGA AGAAAATGAT
TGTAACATTG CACTGTACGA ACACACAATT AATAAAGACA CCACCCACTT GGAGATTGAA
CCCTTCACTC TTCTCGGCGT GTGTGCTGGA CTTATCCCAT ACCCTCACCA TAACCAGTCA
CCGAGAAACA CTTATCAGTG TGCCATGGGG AAACAAGCCA TGGGTACTAT AGGATACAAC
CAGCGAAACA GAATTGATAC TCTCATGTAT CTACTAGCAT ATCCACAAAA ACCCATGGTT
AAGACAAAAA CCATTGAATT GATAGAATTT GAGAAACTGC CAGCTGGACA GAATGCAACA
GTTGCTGTGA TGAGCTATAG TGGCTATGAT ATTGAAGATG CTCTTGTTTT AAACAAGGCC
TCTTTAGACA GAGGCTTTGG GCGTTGCCTT GTATATAAAA ATGCTAAATG TACGTTGAAA
CGATACACCA ATCAGACTTT TGATAAAGTG ATGGGGCCCA TGTTGGATGC TGCTACAAGG
AAACCTATCT GGCGACATGA AATCTTAGAT GCAGATGGTA TTTGTTCTCC AGGTGAGAAA
GTAGAAAACA AACAAGTGCT TGTAAATAAG TCCATGCCCA CAGTGACTCA GATTCCTTTG
GAAGGAAGTA ATGTACCACA GCAACCACAG TACAAAGATG TACCCATAAC CTACAAAGGA
GCAACAGACT CATATATTGA AAAAGTGATG ATATCTTCAA ATGCTGAAGA TGCTTTTCTG
ATCAAAATGC TGCTGAGACA GACAAGGCGT CCAGAAATTG GAGACAAATT CAGCAGTCGT
CATGGGCAAA AAGGTGTTTG TGGCTTGATC GTCCCCCAGG AAGACATGCC ATTTTGTGAT
TCTGGCATCT GTCCGGACAT CATCATGAAC CCACACGGCT TCCCATCACG AATGACGGTG
GGGAAGCTCA TTGAGCTGCT GGCTGGCAAG GCCGGTGTGC TGGACGGCAG ATTCCACTAC
GGCACTGCGT TTGGAGGCAG TAAAGTGAAG GATGTGTGTG AGGACCTCGT TCGCCATGGT
TATAACTACT TGGGGAAAGA CTATGTTACA TCCGGCATCA CAGGTGAGCC CTTAGAAGCA
TACATCTATT TTGGCCCCGT GTACTATCAG AAGCTGAAAC ACATGGTGCT AGATAAAATG
CATGCCCGGG CCCGGGGCCC ACGAGCCGTC CTTACCAGGC AACCCACTGA AGGACGGTCT
CGTGATGGTG GCTTGCGTCT CGGGGAAATG GAACGTGACT GTTTAATCGG TTATGGAGCC
AGTATGCTTT TGCTAGAGAG ACTAATGATT TCAAGTGATG CCTTTGAGGT TGATGTCTGT
GGGCAGTGTG GACTTCTGGG GTATTCTGGC TGGTGCCATT ACTGCAAGTC ATCCTGCCAC
GTGTCTTCCC TCCGTATTCC GTATGCCTGC AAGCTGCTCT TCCAGGAACT ACAGTCTATG
AACATCATCC CCAGGTTAAA ACTGTCCAAG TACAATGAAT GA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_060552.4
CDS223..3624
Misc Feature(1)100..102(+)
Misc Feature(2)298..3609(+)
Misc Feature(3)337..3603(+)
Misc Feature(4)535..2682(+)
Misc Feature(5)1621..3603(+)
Misc Feature(6)1837..2022(+)
Misc Feature(7)2083..2205(+)
Misc Feature(8)2368..3234(+)
Misc Feature(9)2467..3201(+)
Misc Feature(10)2509..3225(+)
Exon (1)1..294
Gene:POLR3B
Gene Synonym:
Exon (2)295..327
Gene:POLR3B
Gene Synonym:
Exon (3)328..384
Gene:POLR3B
Gene Synonym:
Exon (4)385..449
Gene:POLR3B
Gene Synonym:
Exon (5)450..525
Gene:POLR3B
Gene Synonym:
Exon (6)526..626
Gene:POLR3B
Gene Synonym:
Exon (7)627..718
Gene:POLR3B
Gene Synonym:
Exon (8)719..836
Gene:POLR3B
Gene Synonym:
Exon (9)837..945
Gene:POLR3B
Gene Synonym:
Exon (10)946..1068
Gene:POLR3B
Gene Synonym:
Exon (11)1069..1188
Gene:POLR3B
Gene Synonym:
Exon (12)1189..1323
Gene:POLR3B
Gene Synonym:
Exon (13)1324..1485
Gene:POLR3B
Gene Synonym:
Exon (14)1486..1686
Gene:POLR3B
Gene Synonym:
Exon (15)1687..1849
Gene:POLR3B
Gene Synonym:
Exon (16)1850..2003
Gene:POLR3B
Gene Synonym:
Exon (17)2004..2078
Gene:POLR3B
Gene Synonym:
Exon (18)2079..2177
Gene:POLR3B
Gene Synonym:
Exon (19)2178..2305
Gene:POLR3B
Gene Synonym:
Exon (20)2306..2515
Gene:POLR3B
Gene Synonym:
Exon (21)2516..2674
Gene:POLR3B
Gene Synonym:
Exon (22)2675..2792
Gene:POLR3B
Gene Synonym:
Exon (23)2793..2935
Gene:POLR3B
Gene Synonym:
Exon (24)2936..3039
Gene:POLR3B
Gene Synonym:
Exon (25)3040..3206
Gene:POLR3B
Gene Synonym:
Exon (26)3207..3320
Gene:POLR3B
Gene Synonym:
Exon (27)3321..3494
Gene:POLR3B
Gene Synonym:
Exon (28)3495..4273
Gene:POLR3B
Gene Synonym:
Translation
Position Chain Variation Link
2 2 c, t dbSNP:573430566
7 7 a, g dbSNP:545262162
25 25 c, t dbSNP:565582151
33 33 a, g dbSNP:148597447
50 50 c, t dbSNP:73186443
113 113 a, g dbSNP:566540180
117 117 a, g dbSNP:560914710
125 125 a, g dbSNP:530024429
128 128 c, t dbSNP:17219334
143 143 a, g dbSNP:377009599
148 148 -, g dbSNP:372941570
165 165 c, t dbSNP:371977477
179 179 c, g dbSNP:779265499
180 180 a, g dbSNP:376558060
184 184 c, g dbSNP:140312606
185 185 a, c dbSNP:775888994
186 186 g, t dbSNP:373418815
192 192 -, tcta dbSNP:767199959
203 203 c, t dbSNP:373504825
204 204 c, t dbSNP:776160744
208 208 g, t dbSNP:761305811
222 222 c, t dbSNP:117873765
233 233 c, t dbSNP:772862264
236 236 c, t dbSNP:144172154
238 238 a, g dbSNP:766117016
240 240 g, t dbSNP:751318661
253 253 c, t dbSNP:377586797
255 255 a, g dbSNP:767560264
258 258 c, g, t dbSNP:754030235
263 263 a, g dbSNP:779069189
264 264 a, g dbSNP:548223706
275 275 c, t dbSNP:758602438
278 278 a, c, g dbSNP:780334764
279 279 a, g, t dbSNP:769214693
282 282 c, g, t dbSNP:748593339
283 283 c, t dbSNP:370286625
285 285 a, c, g dbSNP:762535171
287 287 c, g dbSNP:774052730
292 292 c, g dbSNP:759363091
307 307 c, g dbSNP:779537305
310 310 c, t dbSNP:778337028
328 328 a, g dbSNP:763829196
330 330 a, g dbSNP:548719279
340 340 a, g dbSNP:753126070
348 348 a, g dbSNP:756485164
352 352 a, g dbSNP:764300320
354 354 a, g dbSNP:754400950
387 387 -, aaa dbSNP:745721628
387 387 a, g dbSNP:748135287
394 394 a, t dbSNP:568682674
396 396 -, aatg dbSNP:771959481
402 402 a, g dbSNP:774453914
407 407 a, g dbSNP:527953383
415 415 c, g dbSNP:767784504
420 420 a, g dbSNP:775696277
429 429 a, t dbSNP:760770690
430 430 a, g dbSNP:764541119
432 432 c, t dbSNP:368827027
435 435 a, t dbSNP:757826726
436 436 a, g dbSNP:765662843
452 452 a, g dbSNP:376800357
466 466 a, g dbSNP:777122841
471 471 c, g dbSNP:762075246
479 479 a, t dbSNP:765643493
480 480 c, t dbSNP:750967094
496 496 a, g dbSNP:763510140
497 497 a, g dbSNP:369375037
498 498 -, t dbSNP:747216457
504 504 c, t dbSNP:766007096
514 514 -, c dbSNP:768881912
516 516 c, g dbSNP:767779527
530 530 g, t dbSNP:780148992
535 535 a, g dbSNP:747058861
538 538 a, g dbSNP:369178623
546 546 a, g dbSNP:752743933
551 551 c, g dbSNP:776736710
553 553 g, t dbSNP:762031872
559 559 a, g dbSNP:770310005
563 563 c, t dbSNP:773657828
564 564 a, c, g dbSNP:372178891
583 583 c, t dbSNP:751146923
593 593 a, g dbSNP:758954024
604 604 c, t dbSNP:369609747
606 606 c, t dbSNP:752324047
621 621 c, t dbSNP:147328031
622 622 a, g dbSNP:777595105
627 627 a, g dbSNP:750363471
644 644 a, g dbSNP:758303166
648 648 c, t dbSNP:781175232
654 654 c, g dbSNP:748225333
656 656 a, g dbSNP:139443783
665 665 c, g dbSNP:373170094
674 674 c, g, t dbSNP:145075371
675 675 a, g dbSNP:376395471
678 678 a, g dbSNP:771426214
691 691 a, g dbSNP:369977235
692 692 a, c dbSNP:746411185
695 695 c, t dbSNP:772602443
699 699 c, t dbSNP:771392826
700 700 a, c, g dbSNP:749479456
706 706 c, g dbSNP:373099408
737 737 a, g dbSNP:747452509
749 749 a, g dbSNP:768190013
759 759 c, t dbSNP:113468238
763 763 c, t dbSNP:776074515
765 765 a, c dbSNP:201182565
768 768 a, g dbSNP:761499674
783 783 c, t dbSNP:769452308
792 792 c, t dbSNP:772944396
793 793 a, g, t dbSNP:545766074
807 807 a, g dbSNP:766028971
808 808 a, g dbSNP:751544859
810 810 a, t dbSNP:759507297
816 816 c, t dbSNP:764291006
818 818 c, t dbSNP:753938916
833 833 c, t dbSNP:147582475
857 857 -, g dbSNP:761939876
874 874 g, t dbSNP:371141763
875 875 g, t dbSNP:79802610
886 886 c, g, t dbSNP:767558518
898 898 a, g dbSNP:761968415
915 915 a, c dbSNP:571717073
923 923 c, t dbSNP:750692716
928 928 a, g dbSNP:758503582
933 933 a, c dbSNP:201300488
934 934 a, t dbSNP:199892569
943 943 a, c dbSNP:751885179
953 953 g, t dbSNP:199782156
955 955 a, g dbSNP:751975109
958 958 a, g dbSNP:755346691
963 963 a, t dbSNP:767801107
984 984 a, g dbSNP:753277030
985 985 a, g dbSNP:140433171
993 993 a, g, t dbSNP:201822852
995 995 a, c dbSNP:117911920
998 998 a, g dbSNP:778723427
1003 1003 a, g dbSNP:201440861
1013 1013 c, t dbSNP:772026926
1018 1018 a, g dbSNP:775102202
1041 1041 c, g dbSNP:747019905
1042 1042 a, g dbSNP:768451113
1051 1051 a, t dbSNP:773404949
1057 1057 a, t dbSNP:368961144
1064 1064 c, t dbSNP:766385955
1082 1082 c, t dbSNP:771028048
1086 1086 a, g dbSNP:376166938
1105 1105 a, g dbSNP:774363956
1108 1108 a, g dbSNP:759803156
1114 1114 a, g dbSNP:772152947
1121 1121 a, g dbSNP:775981204
1145 1145 a, c dbSNP:193156019
1147 1147 a, g dbSNP:369488769
1166 1166 c, t dbSNP:373723723
1171 1171 a, g dbSNP:376426432
1182 1182 -, ccag dbSNP:367995157
1188 1188 a, g dbSNP:764892043
1193 1193 a, g dbSNP:201270085
1195 1195 g, t dbSNP:756111014
1197 1197 a, g dbSNP:145542203
1201 1201 a, t dbSNP:200042871
1207 1207 c, t dbSNP:758437925
1225 1225 a, c dbSNP:780131061
1231 1231 g, t dbSNP:747242779
1233 1233 c, g dbSNP:768888177
1240 1240 c, t dbSNP:148879912
1241 1241 a, g dbSNP:565545064
1246 1246 a, g dbSNP:370376465
1259 1259 a, g dbSNP:748506543
1265 1265 a, t dbSNP:770230205
1278 1278 c, t dbSNP:143599158
1279 1279 a, g dbSNP:763479999
1281 1281 -, a dbSNP:766754661
1303 1303 a, c dbSNP:765830807
1311 1311 a, g dbSNP:757801078
1324 1324 c, t dbSNP:201079775
1324 1324 c, t dbSNP:386457647
1328 1328 -, tatctcttc dbSNP:748218020
1329 1329 a, t dbSNP:763836079
1331 1331 c, t dbSNP:753739949
1333 1333 c, t dbSNP:757194712
1335 1335 c, t dbSNP:141885523
1336 1336 c, g, t dbSNP:568917673
1353 1353 a, c dbSNP:755209771
1369 1369 a, g dbSNP:781583092
1379 1379 a, c dbSNP:748318494
1386 1386 c, t dbSNP:770316358
1387 1387 a, g dbSNP:773665687
1390 1390 c, t dbSNP:548827190
1410 1410 a, g dbSNP:200803445
1419 1419 a, g dbSNP:773801173
1438 1438 a, g dbSNP:759073982
1452 1452 c, g dbSNP:375986407
1455 1455 c, t dbSNP:775154232
1459 1459 a, g dbSNP:760269619
1460 1460 a, g dbSNP:763924026
1461 1461 c, t dbSNP:753635412
1466 1466 c, t dbSNP:199504211
1477 1477 a, g dbSNP:768889169
1482 1482 a, c, t dbSNP:371496625
1485 1485 a, c, t dbSNP:367607316
1491 1491 c, t dbSNP:756473072
1511 1511 a, g dbSNP:778044327
1530 1530 a, g dbSNP:761371993
1533 1533 c, g dbSNP:551945764
1542 1542 a, g dbSNP:753949347
1547 1547 a, g, t dbSNP:201153027
1554 1554 a, g dbSNP:145020083
1558 1558 a, g dbSNP:772535359
1563 1563 c, t dbSNP:545561868
1564 1564 a, g, t dbSNP:746506474
1566 1566 a, g dbSNP:138822077
1569 1569 a, g dbSNP:193106695
1587 1587 a, c dbSNP:565387901
1590 1590 -, ttcccag dbSNP:773229494
1590 1590 c, t dbSNP:140483599
1600 1600 g, t dbSNP:370169112
1608 1608 a, g dbSNP:766417611
1623 1623 a, t dbSNP:74390456
1653 1653 a, g dbSNP:760850969
1667 1667 c, t dbSNP:747108240
1668 1668 a, g dbSNP:754111056
1700 1700 c, t dbSNP:764283322
1710 1710 a, g dbSNP:776540625
1730 1730 a, c dbSNP:267608683
1738 1738 a, g dbSNP:762160281
1739 1739 c, t dbSNP:765361070
1747 1747 -, g dbSNP:750294348
1754 1754 -, t dbSNP:763485186
1755 1755 -, t dbSNP:267608684
1774 1774 c, g, t dbSNP:750584323
1790 1790 a, t dbSNP:138249161
1800 1800 a, g dbSNP:537025390
1802 1802 g, t dbSNP:755422501
1803 1803 c, t dbSNP:780797276
1814 1814 c, t dbSNP:747610772
1824 1824 a, g dbSNP:200983703
1825 1825 a, g dbSNP:755854514
1842 1842 c, t dbSNP:777583980
1847 1847 a, g dbSNP:748882857
1852 1852 a, g dbSNP:755584491
1870 1870 c, t dbSNP:267608688
1874 1874 a, c dbSNP:777378373
1884 1884 a, g dbSNP:753592392
1885 1885 c, t dbSNP:756939086
1887 1887 a, g dbSNP:546320667
1895 1895 c, t dbSNP:745635075
1900 1900 c, t dbSNP:771838685
1901 1901 a, g dbSNP:779858391
1906 1906 a, g dbSNP:746920953
1911 1911 a, c, g dbSNP:200865877
1923 1923 c, t dbSNP:763207067
1924 1924 a, g dbSNP:35983209
1928 1928 a, g dbSNP:551949170
1929 1929 c, t dbSNP:17038450
1942 1942 a, g dbSNP:200126234
1945 1945 c, t dbSNP:767857927
1959 1959 a, g dbSNP:753176222
1963 1963 a, c, t dbSNP:576127663
1965 1965 a, g dbSNP:537703445
1973 1973 a, g dbSNP:753393949
1985 1985 a, t dbSNP:757026963
1998 1998 a, t dbSNP:201223367
2011 2011 a, g dbSNP:147324507
2017 2017 a, g dbSNP:764797827
2026 2026 c, g dbSNP:750061760
2041 2041 a, g dbSNP:758043469
2044 2044 a, g dbSNP:766131152
2053 2053 a, g dbSNP:751369777
2056 2056 c, g dbSNP:754968519
2089 2089 g, t dbSNP:747184457
2095 2095 c, t dbSNP:139376910
2122 2122 a, g dbSNP:781671613
2136 2136 a, c dbSNP:748702792
2145 2145 c, t dbSNP:770333846
2160 2160 a, c, t dbSNP:143400457
2161 2161 a, g dbSNP:755658678
2166 2166 a, c dbSNP:770284337
2169 2169 -, aatt dbSNP:761276079
2169 2169 a, g dbSNP:774024453
2174 2174 a, g dbSNP:527638833
2180 2180 a, g, t dbSNP:144161033
2183 2183 c, t dbSNP:200782069
2189 2189 a, t dbSNP:763755551
2193 2193 a, g dbSNP:148613297
2196 2196 a, g dbSNP:201895619
2198 2198 c, t dbSNP:142094821
2202 2202 a, g dbSNP:751682027
2210 2210 c, t dbSNP:755312623
2217 2217 c, t dbSNP:767867634
2220 2220 c, t dbSNP:369468138
2221 2221 a, g dbSNP:756536922
2223 2223 a, c, g dbSNP:777951679
2241 2241 a, g dbSNP:757676950
2262 2262 a, g dbSNP:778462763
2265 2265 a, g dbSNP:372517855
2274 2274 c, t dbSNP:376791688
2277 2277 c, g, t dbSNP:10861607
2296 2296 -, c dbSNP:764859439
2326 2326 c, t dbSNP:201401034
2347 2347 a, t dbSNP:773318236
2358 2358 a, g dbSNP:139146614
2368 2368 -, a dbSNP:758413153
2374 2374 c, t dbSNP:772327533
2377 2377 a, g dbSNP:775402995
2380 2380 a, g dbSNP:761026189
2383 2383 a, t dbSNP:374359855
2392 2392 a, c dbSNP:754023038
2395 2395 a, g dbSNP:762195295
2401 2401 c, g, t dbSNP:375960295
2402 2402 c, t dbSNP:758867273
2405 2405 c, t dbSNP:748464579
2430 2430 a, t dbSNP:200497639
2440 2440 a, g dbSNP:17038460
2442 2442 a, g dbSNP:754450206
2447 2447 c, t dbSNP:528154460
2452 2452 a, g dbSNP:747766146
2453 2453 c, t dbSNP:769736904
2476 2476 g, t dbSNP:201716779
2481 2481 c, t dbSNP:199743272
2495 2495 a, g dbSNP:749277976
2500 2500 a, g, t dbSNP:146513209
2516 2516 g, t dbSNP:770703901
2524 2524 c, t dbSNP:371453512
2525 2525 a, g dbSNP:267608687
2529 2529 c, t dbSNP:768665790
2531 2531 a, t dbSNP:748805276
2533 2533 a, g dbSNP:776660787
2534 2534 c, t dbSNP:748432049
2555 2555 c, t dbSNP:375480706
2556 2556 a, g dbSNP:150800622
2564 2564 a, g dbSNP:538577233
2573 2573 a, c dbSNP:766728879
2576 2576 a, t dbSNP:774746326
2584 2584 c, g dbSNP:143507316
2601 2601 c, t dbSNP:766980809
2608 2608 a, g dbSNP:368613977
2609 2609 a, t dbSNP:755889644
2616 2616 c, t dbSNP:763853811
2622 2622 a, g dbSNP:753499989
2629 2629 a, g dbSNP:372387469
2636 2636 a, g dbSNP:146772688
2643 2643 a, g dbSNP:377149913
2645 2645 c, t dbSNP:573261309
2655 2655 a, c dbSNP:552412004
2658 2658 c, t dbSNP:758347944
2681 2681 a, c dbSNP:777811614
2685 2685 a, g dbSNP:34681274
2704 2704 c, g, t dbSNP:749516917
2705 2705 c, t dbSNP:779203620
2708 2708 a, g dbSNP:200502989
2715 2715 c, t dbSNP:764111608
2719 2719 c, g dbSNP:772499805
2722 2722 a, g dbSNP:776161810
2723 2723 c, t dbSNP:148931372
2742 2742 a, g dbSNP:768321161
2751 2751 -, aatgtac dbSNP:748423263
2752 2752 a, c dbSNP:776199937
2753 2753 a, g dbSNP:547835696
2754 2754 c, t dbSNP:764952250
2757 2757 a, g dbSNP:749973787
2769 2769 a, g dbSNP:752119970
2770 2770 c, t dbSNP:766115864
2787 2787 c, t dbSNP:751549093
2790 2790 a, g dbSNP:754879484
2792 2792 c, t dbSNP:777896021
2795 2795 a, g dbSNP:113715233
2798 2798 a, g dbSNP:766203968
2818 2818 a, g dbSNP:751352752
2830 2830 a, g dbSNP:759527548
2837 2837 c, g dbSNP:369017509
2850 2850 a, c dbSNP:752513905
2854 2854 a, g dbSNP:201627534
2863 2863 -, at dbSNP:777831969
2870 2870 c, t dbSNP:757392794
2890 2890 c, t dbSNP:778812401
2891 2891 a, g dbSNP:750694928
2900 2900 c, t dbSNP:758685804
2903 2903 g, t dbSNP:780618644
2908 2908 a, t dbSNP:267608685
2915 2915 a, g dbSNP:143703583
2920 2920 c, t dbSNP:755326914
2931 2931 a, g dbSNP:781737270
2949 2949 g, t dbSNP:201781254
2950 2950 a, g, t dbSNP:569069911
2952 2952 c, t dbSNP:538183170
2953 2953 a, g dbSNP:770365711
2960 2960 a, c dbSNP:774026760
2973 2973 a, g dbSNP:745477859
2981 2981 a, t dbSNP:771954727
2991 2991 c, g dbSNP:554886814
2996 2996 c, t dbSNP:775141057
2997 2997 a, g dbSNP:769294366
3000 3000 c, g dbSNP:267608689
3011 3011 a, c dbSNP:763947981
3013 3013 c, g dbSNP:373101426
3018 3018 c, t dbSNP:141030994
3031 3031 c, t dbSNP:763154774
3042 3042 g, t dbSNP:139255984
3045 3045 a, g dbSNP:757733299
3057 3057 a, g dbSNP:778450287
3063 3063 a, g dbSNP:749912429
3064 3064 a, g, t dbSNP:757853544
3065 3065 c, t dbSNP:779604405
3067 3067 a, g dbSNP:746622682
3069 3069 c, t dbSNP:373826323
3070 3070 a, c dbSNP:781100960
3075 3075 c, t dbSNP:748165243
3076 3076 a, g dbSNP:201465114
3077 3077 a, g dbSNP:773226013
3082 3082 c, t dbSNP:759539441
3086 3086 a, g dbSNP:553733271
3087 3087 c, t dbSNP:143284189
3095 3095 g, t dbSNP:368515122
3097 3097 c, t dbSNP:764486483
3099 3099 c, t dbSNP:148708579
3101 3101 a, g dbSNP:762105430
3106 3106 a, c dbSNP:765733223
3110 3110 c, t dbSNP:750899096
3121 3121 a, c dbSNP:200865021
3124 3124 a, g dbSNP:765891224
3127 3127 a, g dbSNP:200477676
3150 3150 -, gagg dbSNP:759862082
3150 3150 c, t dbSNP:754671920
3151 3151 a, g dbSNP:199545845
3154 3154 c, t dbSNP:747972980
3155 3155 a, g dbSNP:117293015
3158 3158 a, g dbSNP:777603547
3160 3160 a, g dbSNP:199865077
3165 3165 c, t dbSNP:372059822
3166 3166 a, g dbSNP:368213717
3182 3182 a, c dbSNP:138378720
3184 3184 -, ta dbSNP:772463810
3185 3185 a, g dbSNP:149257714
3190 3190 a, g dbSNP:372036820
3195 3195 c, t dbSNP:747265286
3198 3198 a, c dbSNP:768877018
3210 3210 a, g dbSNP:144485339
3214 3214 g, t dbSNP:759833434
3216 3216 a, g dbSNP:753657104
3218 3218 a, g dbSNP:765573891
3220 3220 a, g dbSNP:756931770
3222 3222 a, g dbSNP:778937914
3230 3230 a, g dbSNP:368953286
3234 3234 c, t dbSNP:567765509
3237 3237 c, t dbSNP:148438504
3240 3240 c, t dbSNP:373346251
3241 3241 a, g, t dbSNP:375472185
3257 3257 c, t dbSNP:749670593
3271 3271 c, t dbSNP:771161167
3273 3273 a, g dbSNP:144051136
3288 3288 a, c, t dbSNP:145991322
3294 3294 c, t dbSNP:369730210
3304 3304 c, t dbSNP:775137613
3305 3305 a, g dbSNP:758183544
3310 3310 a, g dbSNP:760305780
3321 3321 a, g dbSNP:746448456
3324 3324 a, g dbSNP:370631015
3327 3327 c, t dbSNP:778281040
3330 3330 c, t dbSNP:760261511
3348 3348 g, t dbSNP:373822144
3363 3363 c, t dbSNP:776391361
3364 3364 a, g dbSNP:761337432
3366 3366 c, g dbSNP:568662073
3368 3368 a, g dbSNP:79171601
3369 3369 a, g dbSNP:772975950
3384 3384 c, t dbSNP:762678539
3390 3390 c, t dbSNP:139920513
3395 3395 a, g dbSNP:751459271
3406 3406 a, g dbSNP:756242647
3408 3408 a, g dbSNP:201777932
3417 3417 a, g dbSNP:143441199
3420 3420 a, g dbSNP:745914949
3434 3434 a, c dbSNP:779482867
3444 3444 c, t dbSNP:746252168
3455 3455 a, g dbSNP:758792141
3459 3459 c, t dbSNP:188914862
3462 3462 c, t dbSNP:550453071
3475 3475 c, t dbSNP:370363631
3480 3480 c, g dbSNP:747449371
3491 3491 g, t dbSNP:770376797
3495 3495 a, g dbSNP:768612175
3513 3513 a, g dbSNP:759579343
3524 3524 c, t dbSNP:771921629
3535 3535 c, t dbSNP:575865538
3536 3536 a, g dbSNP:762004021
3539 3539 c, t dbSNP:765382317
3543 3543 a, g dbSNP:113017214
3546 3546 c, t dbSNP:763259986
3554 3554 a, g dbSNP:766823201
3560 3560 c, t dbSNP:751882154
3570 3570 a, g dbSNP:151232276
3576 3576 g, t dbSNP:781580610
3578 3578 c, t dbSNP:753201056
3580 3580 a, g dbSNP:755670879
3592 3592 c, g dbSNP:777235804
3596 3596 c, g dbSNP:749008585
3597 3597 a, g dbSNP:770560138
3612 3612 c, g dbSNP:201527706
3617 3617 a, g dbSNP:200967068
3618 3618 c, t dbSNP:13561
3619 3619 a, g dbSNP:775335616
3625 3625 c, g dbSNP:149990218
3629 3629 a, g dbSNP:373363499
3638 3638 a, g dbSNP:773410138
3639 3639 a, g, t dbSNP:763068456
3643 3643 c, t dbSNP:751764949
3648 3648 a, g dbSNP:759841627
3659 3659 a, g dbSNP:767902490
3662 3662 a, c, g dbSNP:377492248
3663 3663 a, c dbSNP:756609861
3670 3670 a, g dbSNP:371809211
3674 3674 c, t dbSNP:777325577
3675 3675 a, g dbSNP:189041433
3684 3684 a, g dbSNP:560425343
3700 3700 c, t dbSNP:754054633
3722 3722 c, t dbSNP:532224514
3727 3727 c, t dbSNP:545951495
3733 3733 c, t dbSNP:759691487
3735 3735 c, g dbSNP:562644313
3749 3749 -, a dbSNP:200331241
3759 3759 a, t dbSNP:531592970
3787 3787 a, t dbSNP:765299949
3803 3803 a, t dbSNP:376396754
3819 3819 c, t dbSNP:547822703
3841 3841 a, g dbSNP:752808674
3862 3862 c, t dbSNP:149535796
3872 3872 g, t dbSNP:181864410
3876 3876 g, t dbSNP:778314251
3896 3896 c, t dbSNP:547073426
3938 3938 g, t dbSNP:570177691
3941 3941 a, c dbSNP:143084704
3966 3966 c, g dbSNP:186425739
3971 3971 a, g dbSNP:2288266
3996 3996 a, g dbSNP:557970332
4007 4007 c, t dbSNP:191071027
4050 4050 c, t dbSNP:781241574
4065 4065 c, t dbSNP:555034182
4066 4066 a, g dbSNP:574873455
4079 4079 c, t dbSNP:540600406
4080 4080 a, g dbSNP:554332080
4116 4116 a, t dbSNP:780838654
4120 4120 c, g dbSNP:745461447
4145 4145 g, t dbSNP:577222793
4168 4168 a, g dbSNP:545689984
4180 4180 -, a dbSNP:3217286
4183 4183 a, c dbSNP:769435306
4189 4189 a, g dbSNP:55715506
4206 4206 c, g dbSNP:75217257
4211 4211 c, g dbSNP:576237770
4226 4226 c, t dbSNP:541699640

Target ORF information:

RefSeq Version NM_018082
Organism Homo sapiens (human)
Definition Homo sapiens polymerase (RNA) III (DNA directed) polypeptide B (POLR3B), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_018082

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
ATGGACGTGC TAGCGGAGGA GTTTGGGAAC CTGACTCCGG AGCAGCTGGC GGCGCCGATC 
CCGACTGTAG AGGAAAAATG GAGGCTGCTT CCAGCATTTT TAAAGGTGAA AGGCCTTGTG
AAACAGCATA TAGATTCATT TAACTATTTC ATTAATGTAG AGATAAAGAA GATAATGAAA
GCCAATGAAA AGGTTACAAG TGACGCTGAC CCTATGTGGT ACTTAAAATA TCTTAATATC
TATGTTGGGC TTCCTGATGT TGAAGAAAGC TTCAATGTAA CTAGACCAGT GTCCCCTCAT
GAGTGCCGTT TGAGAGACAT GACATACTCT GCCCCTATTA CAGTGGATAT TGAATATACC
CGAGGCAGCC AGAGGATCAT CCGCAATGCC TTACCTATCG GCAGAATGCC CATAATGCTA
CGTAGTTCAA ACTGTGTTCT TACAGGAAAA ACGCCAGCAG AATTTGCCAA ACTGAACGAA
TGTCCCTTAG ATCCAGGTGG CTACTTCATT GTTAAAGGAG TAGAAAAAGT TATTCTTATC
CAAGAGCAGC TGTCTAAGAA CAGGATCATC GTGGAGGCTG ATAGAAAAGG GGCTGTTGGA
GCTTCAGTTA CCAGCTCTAC CCATGAGAAA AAAAGCAGAA CCAATATGGC TGTGAAACAA
GGACGATTTT ATTTGAGGCA TAATACTTTG TCAGAAGATA TACCCATTGT CATCATATTT
AAGGCCATGG GTGTTGAGAG TGACCAGGAA ATTGTGCAGA TGATTGGAAC AGAGGAGCAC
GTGATGGCTG CATTTGGGCC CAGTCTGGAA GAGTGCCAGA AAGCTCAGAT TTTCACACAG
ATGCAGGCAT TAAAATATAT AGGGAACAAA GTAAGAAGGC AAAGGATGTG GGGAGGTGGA
CCAAAGAAAA CCAAAATAGA AGAAGCAAGA GAGCTCCTGG CTTCCACCAT TCTGACCCAT
GTCCCAGTTA AGGAATTCAA TTTCCGAGCC AAATGTATCT ATACTGCAGT GATGGTGCGA
AGAGTTATTC TGGCCCAAGG AGATAATAAA GTTGACGACA GAGATTATTA TGGTAACAAG
CGACTGGAAT TGGCAGGACA GCTTTTATCT CTTCTTTTTG AAGACTTGTT CAAAAAATTT
AATTCTGAAA TGAAAAAGAT TGCCGACCAG GTGATTCCTA AGCAAAGAGC AGCCCAGTTT
GATGTTGTCA AACACATGCG CCAAGACCAG ATCACCAATG GCATGGTGAA TGCTATTTCT
ACCGGAAATT GGTCTTTAAA GAGATTTAAA ATGGACCGCC AGGGTGTAAC CCAAGTGCTG
TCTCGCTTGT CATATATATC CGCACTGGGC ATGATGACAA GAATCTCTTC CCAGTTTGAA
AAAACGAGAA AAGTGAGTGG TCCTCGCTCC CTCCAGCCAT CTCAGTGGGG AATGCTGTGT
CCTTCGGACA CTCCTGAAGG AGAGGCATGT GGTTTGGTTA AAAACTTGGC CCTTATGACA
CACATCACAA CTGATATGGA AGATGGACCC ATTGTTAAAT TAGCCAGTAA CTTGGGAGTA
GAAGATGTGA ATTTATTATG TGGGGAAGAG CTCTCTTACC CAAATGTGTT TCTTGTCTTT
CTTAATGGTA ACATCTTAGG TGTCATTCGA GACCACAAAA AGCTAGTGAA TACATTTCGA
CTCATGAGAA GAGCAGGATA TATCAATGAA TTTGTTTCCA TCTCAACAAA TCTTACAGAT
CGATGTGTCT ATATTTCTTC TGATGGGGGA AGGCTATGCA GACCCTACAT AATTGTCAAG
AAACAGAAGC CAGCAGTCAC AAATAAACAT ATGGAAGAGC TGGCCCAAGG GTACAGGAAT
TTTGAAGATT TCTTACATGA GAGTCTGGTT GAATATTTAG ATGTGAATGA AGAAAATGAT
TGTAACATTG CACTGTACGA ACACACAATT AATAAAGACA CCACCCACTT GGAGATTGAA
CCCTTCACTC TTCTCGGCGT GTGTGCTGGA CTTATCCCAT ACCCTCACCA TAACCAGTCA
CCGAGAAACA CTTATCAGTG TGCCATGGGG AAACAAGCCA TGGGTACTAT AGGATACAAC
CAGCGAAACA GAATTGATAC TCTCATGTAT CTACTAGCAT ATCCACAAAA ACCCATGGTT
AAGACAAAAA CCATTGAATT GATAGAATTT GAGAAACTGC CAGCTGGACA GAATGCAACA
GTTGCTGTGA TGAGCTATAG TGGCTATGAT ATTGAAGATG CTCTTGTTTT AAACAAGGCC
TCTTTAGACA GAGGCTTTGG GCGTTGCCTT GTATATAAAA ATGCTAAATG TACGTTGAAA
CGATACACCA ATCAGACTTT TGATAAAGTG ATGGGGCCCA TGTTGGATGC TGCTACAAGG
AAACCTATCT GGCGACATGA AATCTTAGAT GCAGATGGTA TTTGTTCTCC AGGTGAGAAA
GTAGAAAACA AACAAGTGCT TGTAAATAAG TCCATGCCCA CAGTGACTCA GATTCCTTTG
GAAGGAAGTA ATGTACCACA GCAACCACAG TACAAAGATG TACCCATAAC CTACAAAGGA
GCAACAGACT CATATATTGA AAAAGTGATG ATATCTTCAA ATGCTGAAGA TGCTTTTCTG
ATCAAAATGC TGCTGAGACA GACAAGGCGT CCAGAAATTG GAGACAAATT CAGCAGTCGT
CATGGGCAAA AAGGTGTTTG TGGCTTGATC GTCCCCCAGG AAGACATGCC ATTTTGTGAT
TCTGGCATCT GTCCGGACAT CATCATGAAC CCACACGGCT TCCCATCACG AATGACGGTG
GGGAAGCTCA TTGAGCTGCT GGCTGGCAAG GCCGGTGTGC TGGACGGCAG ATTCCACTAC
GGCACTGCGT TTGGAGGCAG TAAAGTGAAG GATGTGTGTG AGGACCTCGT TCGCCATGGT
TATAACTACT TGGGGAAAGA CTATGTTACA TCCGGCATCA CAGGTGAGCC CTTAGAAGCA
TACATCTATT TTGGCCCCGT GTACTATCAG AAGCTGAAAC ACATGGTGCT AGATAAAATG
CATGCCCGGG CCCGGGGCCC ACGAGCCGTC CTTACCAGGC AACCCACTGA AGGACGGTCT
CGTGATGGTG GCTTGCGTCT CGGGGAAATG GAACGTGACT GTTTAATCGG TTATGGAGCC
AGTATGCTTT TGCTAGAGAG ACTAATGATT TCAAGTGATG CCTTTGAGGT TGATGTCTGT
GGGCAGTGTG GACTTCTGGG GTATTCTGGC TGGTGCCATT ACTGCAAGTC ATCCTGCCAC
GTGTCTTCCC TCCGTATTCC GTATGCCTGC AAGCTGCTCT TCCAGGAACT ACAGTCTATG
AACATCATCC CCAGGTTAAA ACTGTCCAAG TACAATGAAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.