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PBK PDZ binding kinase [Homo sapiens (human)]

Gene Symbol PBK
Entrez Gene ID 55872
Full Name PDZ binding kinase
Synonyms CT84, HEL164, Nori-3, SPK, TOPK
General protein information
Preferred Names
lymphokine-activated killer T-cell-originated protein kinase
Names
lymphokine-activated killer T-cell-originated protein kinase
cancer/testis antigen 84
MAPKK-like protein kinase
serine/threonine protein kinase
T-LAK cell-originated protein kinase
spermatogenesis-related protein kinase
NP_060962.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

8

8p21.2

Summary This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]. lac of sum
Disorder MIM:

611210

Disorder Html:





The following PBK gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PBK gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu03043 XM_006716368 PREDICTED: Homo sapiens PDZ binding kinase (PBK), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$139.3
$199
OHu03043 NM_018492 Homo sapiens PDZ binding kinase (PBK), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$139.3
$199
OHu04739 NM_001278945 Homo sapiens PDZ binding kinase (PBK), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $319

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu03043
Accession Version XM_006716368.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 969bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product lymphokine-activated killer T-cell-originated protein kinase isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167187.2) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578815393. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAAGGGA TCAGTAATTT CAAGACACCA AGCAAATTAT CAGAAAAAAA GAAATCTGTA 
TTATGTTCAA CTCCAACTAT AAATATCCCG GCCTCTCCGT TTATGCAGAA GCTTGGCTTT
GGTACTGGGG TAAATGTGTA CCTAATGAAA AGATCTCCAA GAGGTTTGTC TCATTCTCCT
TGGGCTGTAA AAAAGATTAA TCCTATATGT AATGATCATT ATCGAAGTGT GTATCAAAAG
AGACTAATGG ATGAAGCTAA GATTTTGAAA AGCCTTCATC ATCCAAACAT TGTTGGTTAT
CGTGCTTTTA CTGAAGCCAA TGATGGCAGT CTGTGTCTTG CTATGGAATA TGGAGGTGAA
AAGTCTCTAA ATGACTTAAT AGAAGAACGA TATAAAGCCA GCCAAGATCC TTTTCCAGCA
GCCATAATTT TAAAAGTTGC TTTGAATATG GCAAGAGGGT TAAAGTATCT GCACCAAGAA
AAGAAACTGC TTCATGGAGA CATAAAGTCT TCAAATGTTG TAATTAAAGG CGATTTTGAA
ACAATTAAAA TCTGTGATGT AGGAGTCTCT CTACCACTGG ATGAAAATAT GACTGTGACT
GACCCTGAGG CTTGTTACAT TGGCACAGAG CCATGGAAAC CCAAAGAAGC TGTGGAGGAG
AATGGTGTTA TTACTGACAA GGCAGACATA TTTGCCTTTG GCCTTACTTT GTGGGAAATG
ATGACTTTAT CGATTCCACA CATTAATCTT TCAAATGATG ATGATGATGA AGATAAAACT
TTTGATGAAA GTGATTTTGA TGATGAAGCA TACTATGCAG CGTTGGGAAC TAGGCCACCT
ATTAATATGG AAGAACTGGA TGAATCATAC CAGAAAGTAA TTGAACTCTT CTCTGTATGC
ACTAATGAAG ACCCTAAAGA TCGTCCTTCT GCTGCACACA TTGTTGAAGC TCTGGAAACA
GATGTCTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_006716431.1
CDS389..1357
Misc Feature(1)482..1351(+)
Misc Feature(2)488..1336(+)
Misc Feature(3)500..1021(+)
Misc Feature(4)500..946(+)
Misc Feature(5)512..1021(+)
Misc Feature(6)941..1021(+)
Translation
Position Chain Variation Link
45 45 a, c, g dbSNP:116239149
65 65 a, g dbSNP:573452846
70 70 a, g dbSNP:186272043
72 72 a, g dbSNP:112318817
93 93 c, t dbSNP:759145506
129 129 c, t dbSNP:776002155
137 137 a, c, g dbSNP:543164773
153 153 a, g dbSNP:28407456
159 159 -, c dbSNP:772551082
182 182 a, g dbSNP:180705165
199 199 c, g dbSNP:572331315
203 203 a, g dbSNP:537179694
217 217 a, g dbSNP:144063110
228 228 a, c dbSNP:539738315
246 246 a, t dbSNP:557707522
254 254 a, c dbSNP:772954065
268 268 a, g dbSNP:769179029
272 272 a, g dbSNP:534326554
277 277 c, t dbSNP:565926433
287 287 c, t dbSNP:549049653
296 296 c, t dbSNP:535266291
299 299 a, g dbSNP:369481503
300 300 -, g dbSNP:747064804
341 341 c, g dbSNP:11539583
347 347 a, g dbSNP:3735743
348 348 a, c dbSNP:3735744
353 353 c, g dbSNP:530879259
358 358 a, g dbSNP:776119884
369 369 a, g dbSNP:202051224
392 392 a, g dbSNP:150991972
397 397 a, g dbSNP:368149140
407 407 a, t dbSNP:142678781
422 422 a, g dbSNP:374747017
428 428 c, t dbSNP:749430716
430 430 a, g dbSNP:777701544
435 435 a, g dbSNP:559081825
456 456 c, t dbSNP:114501644
475 475 a, c dbSNP:749465711
477 477 c, t dbSNP:376363789
478 478 a, g dbSNP:769704505
479 479 g, t dbSNP:748711866
480 480 c, t dbSNP:576873768
486 486 c, t dbSNP:755512158
487 487 a, g dbSNP:11539582
499 499 a, g dbSNP:55973425
518 518 -, g dbSNP:745360327
519 519 c, t dbSNP:758139536
520 520 a, g dbSNP:35230929
527 527 c, t dbSNP:199663154
529 529 c, t dbSNP:555099444
534 534 c, t dbSNP:756678174
538 538 a, c dbSNP:373317946
541 541 a, c dbSNP:541416252
542 542 g, t dbSNP:745560003
544 544 g, t dbSNP:778466975
546 546 c, t dbSNP:756909961
547 547 a, g dbSNP:753400716
551 551 a, g dbSNP:763588842
560 560 c, t dbSNP:200725164
566 566 c, t dbSNP:756047700
578 578 a, g dbSNP:201032351
582 582 a, g dbSNP:752572454
591 591 a, c dbSNP:767366634
596 596 c, t dbSNP:367624592
597 597 g, t dbSNP:751339054
605 605 -, cat dbSNP:751279030
609 609 a, t dbSNP:572508534
611 611 c, t dbSNP:555494869
615 615 c, g dbSNP:369154408
617 617 -, gtgt dbSNP:763908468
620 620 c, t dbSNP:112129421
622 622 c, t dbSNP:753244295
630 630 c, g dbSNP:776920066
632 632 c, g dbSNP:768791080
640 640 c, t dbSNP:761280907
648 648 a, t dbSNP:62001048
661 661 c, t dbSNP:772596385
668 668 c, t dbSNP:746263867
669 669 a, t dbSNP:779320923
673 673 a, c dbSNP:770554100
677 677 -, att dbSNP:752618579
681 681 c, t dbSNP:576669630
685 685 c, t dbSNP:772196242
689 689 c, t dbSNP:754938337
690 690 a, g dbSNP:746900679
694 694 g, t dbSNP:779729707
707 707 a, g dbSNP:758222396
708 708 a, g dbSNP:3779620
709 709 c, t dbSNP:764456498
714 714 a, g dbSNP:756387355
721 721 a, g dbSNP:752783878
723 723 a, g dbSNP:373579758
725 725 c, t dbSNP:142068654
727 727 c, t dbSNP:768760254
731 731 a, g dbSNP:766760760
732 732 a, t dbSNP:763346850
734 734 g, t dbSNP:773544696
736 736 a, g dbSNP:769494518
739 739 g, t dbSNP:1675236
742 742 a, g dbSNP:747834390
744 744 g, t dbSNP:185478648
745 745 c, t dbSNP:768158056
749 749 a, g dbSNP:746944771
753 753 c, g dbSNP:780020966
768 768 c, t dbSNP:201842147
776 776 c, t dbSNP:745711431
777 777 a, g dbSNP:371557868
778 778 -, acga dbSNP:761978341
802 802 c, t dbSNP:778842443
805 805 a, c dbSNP:756407655
806 806 c, g dbSNP:752904921
809 809 a, g dbSNP:767514634
812 812 a, g dbSNP:755045401
816 816 c, t dbSNP:751562351
824 824 g, t dbSNP:766921897
828 828 a, c dbSNP:763438217
840 840 c, t dbSNP:556489077
843 843 a, g dbSNP:765520589
855 855 a, g dbSNP:763861092
861 861 a, c dbSNP:760236167
862 862 a, c dbSNP:201933253
871 871 -, gaa dbSNP:770596213
891 891 c, t dbSNP:771646980
905 905 a, g dbSNP:759566784
907 907 -, tgt dbSNP:777299680
908 908 g, t dbSNP:774389423
919 919 c, t dbSNP:770742289
920 920 a, g, t dbSNP:201290873
926 926 a, g dbSNP:768990251
929 929 a, g dbSNP:747168583
933 933 -, ttaa dbSNP:758125261
933 933 g, t dbSNP:780122465
938 938 a, t dbSNP:758426627
940 940 c, t dbSNP:750962230
948 948 c, t dbSNP:779518210
950 950 c, g dbSNP:757687216
955 955 c, g dbSNP:138952065
957 957 -, ctct dbSNP:752426328
959 959 c, t dbSNP:370697278
962 962 a, c dbSNP:200662690
970 970 c, t dbSNP:760386214
975 975 -, a dbSNP:778811189
985 985 a, g dbSNP:767327170
996 996 -, g dbSNP:35061575
1029 1029 a, c dbSNP:754663737
1042 1042 a, g dbSNP:751148854
1047 1047 a, g dbSNP:765740749
1048 1048 c, g dbSNP:17057901
1053 1053 a, g dbSNP:772975178
1055 1055 a, g dbSNP:765114169
1057 1057 c, t dbSNP:761639027
1066 1066 c, t dbSNP:369509839
1070 1070 a, g dbSNP:772342394
1072 1072 a, g dbSNP:746019557
1081 1081 -, t dbSNP:758009033
1102 1102 c, g dbSNP:774498834
1108 1108 g, t dbSNP:770864767
1109 1109 a, c dbSNP:36086402
1119 1119 c, t dbSNP:778181131
1120 1120 a, g dbSNP:2272691
1130 1130 a, t dbSNP:748580344
1139 1139 -, t dbSNP:751746598
1142 1142 -, aat dbSNP:764210457
1142 1142 a, g dbSNP:143824466
1146 1146 a, g dbSNP:754682271
1150 1150 c, t dbSNP:751116684
1156 1156 -, tga dbSNP:775693610
1156 1156 g, t dbSNP:765961447
1158 1158 -, tga dbSNP:763304019
1158 1158 a, g dbSNP:116080983
1170 1170 c, t dbSNP:763920061
1180 1180 c, t dbSNP:760422001
1185 1185 -, tt dbSNP:777281564
1197 1197 c, g dbSNP:141116063
1198 1198 a, g dbSNP:766524296
1207 1207 a, c dbSNP:763169761
1209 1209 c, t dbSNP:377305728
1210 1210 a, c, g dbSNP:2294092
1211 1211 c, t dbSNP:777244902
1215 1215 a, g dbSNP:769244420
1229 1229 a, g dbSNP:558321363
1230 1230 g, t dbSNP:780404879
1233 1233 a, c dbSNP:372784235
1236 1236 -, t dbSNP:770504237
1255 1255 -, atca dbSNP:746499746
1257 1257 a, g dbSNP:745525194
1260 1260 a, g dbSNP:778448107
1274 1274 c, t dbSNP:534955062
1278 1278 -, tctct dbSNP:777405490
1282 1282 g, t dbSNP:756731963
1286 1286 c, t dbSNP:753308198
1291 1291 c, t dbSNP:777713260
1296 1296 a, g dbSNP:756023481
1302 1302 -, c dbSNP:771590512
1302 1302 c, t dbSNP:752440460
1303 1303 g, t dbSNP:767340181
1307 1307 g, t dbSNP:763142735
1310 1310 a, c, t dbSNP:765445598
1311 1311 a, g, t dbSNP:776800823
1314 1314 c, t dbSNP:764518967
1316 1316 g, t dbSNP:761173443
1327 1327 c, t dbSNP:775781182
1328 1328 a, g dbSNP:772464104
1329 1329 g, t dbSNP:745563063
1333 1333 c, g, t dbSNP:112670476
1348 1348 a, g dbSNP:770524940
1349 1349 a, g dbSNP:748812180
1351 1351 c, t dbSNP:371650486
1365 1365 c, t dbSNP:777198967
1367 1367 c, g dbSNP:370636900
1373 1373 a, c dbSNP:748104410
1377 1377 c, g dbSNP:780898852
1384 1384 g, t dbSNP:202048382
1385 1385 c, t dbSNP:754770637
1386 1386 a, g dbSNP:1052873
1394 1394 c, g dbSNP:765577188
1396 1396 c, g dbSNP:764168548
1403 1403 c, g dbSNP:757494228
1423 1423 c, t dbSNP:769490128
1434 1434 a, t dbSNP:762797071
1436 1436 c, t dbSNP:548632577
1438 1438 a, g dbSNP:535195013
1454 1454 a, g dbSNP:775171639
1455 1455 c, t dbSNP:569262311
1460 1460 c, g dbSNP:1052874
1509 1509 a, g dbSNP:533243892
1530 1530 a, g dbSNP:182928344
1534 1534 c, t dbSNP:111683270
1567 1567 g, t dbSNP:6986820
1599 1599 c, t dbSNP:527530104
1670 1670 c, t dbSNP:190773208
1674 1674 c, t dbSNP:543118735
1707 1707 a, t dbSNP:115017161
1710 1710 a, t dbSNP:143110122
1769 1769 c, t dbSNP:112744328
1805 1805 c, g dbSNP:578195214
1824 1824 a, c dbSNP:558197709
1871 1871 c, t dbSNP:186276247
1879 1879 -, tt dbSNP:756860081
1893 1893 -, tct dbSNP:397976384
1893 1893 a, t dbSNP:79343602
1894 1894 -, tct dbSNP:72602653
1896 1896 -, ctt, tct dbSNP:60576879
1897 1897 -, ctt dbSNP:149449393
1945 1945 a, g dbSNP:570089943
1970 1970 c, t dbSNP:10092096
1994 1994 a, g dbSNP:145754266
1997 1997 c, t dbSNP:535138327
2038 2038 -, aga dbSNP:57448874
2040 2040 a, g dbSNP:201300164

Target ORF information:

RefSeq Version XM_006716368
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens PDZ binding kinase (PBK), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006716368

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAAGGGA TCAGTAATTT CAAGACACCA AGCAAATTAT CAGAAAAAAA GAAATCTGTA 
TTATGTTCAA CTCCAACTAT AAATATCCCG GCCTCTCCGT TTATGCAGAA GCTTGGCTTT
GGTACTGGGG TAAATGTGTA CCTAATGAAA AGATCTCCAA GAGGTTTGTC TCATTCTCCT
TGGGCTGTAA AAAAGATTAA TCCTATATGT AATGATCATT ATCGAAGTGT GTATCAAAAG
AGACTAATGG ATGAAGCTAA GATTTTGAAA AGCCTTCATC ATCCAAACAT TGTTGGTTAT
CGTGCTTTTA CTGAAGCCAA TGATGGCAGT CTGTGTCTTG CTATGGAATA TGGAGGTGAA
AAGTCTCTAA ATGACTTAAT AGAAGAACGA TATAAAGCCA GCCAAGATCC TTTTCCAGCA
GCCATAATTT TAAAAGTTGC TTTGAATATG GCAAGAGGGT TAAAGTATCT GCACCAAGAA
AAGAAACTGC TTCATGGAGA CATAAAGTCT TCAAATGTTG TAATTAAAGG CGATTTTGAA
ACAATTAAAA TCTGTGATGT AGGAGTCTCT CTACCACTGG ATGAAAATAT GACTGTGACT
GACCCTGAGG CTTGTTACAT TGGCACAGAG CCATGGAAAC CCAAAGAAGC TGTGGAGGAG
AATGGTGTTA TTACTGACAA GGCAGACATA TTTGCCTTTG GCCTTACTTT GTGGGAAATG
ATGACTTTAT CGATTCCACA CATTAATCTT TCAAATGATG ATGATGATGA AGATAAAACT
TTTGATGAAA GTGATTTTGA TGATGAAGCA TACTATGCAG CGTTGGGAAC TAGGCCACCT
ATTAATATGG AAGAACTGGA TGAATCATAC CAGAAAGTAA TTGAACTCTT CTCTGTATGC
ACTAATGAAG ACCCTAAAGA TCGTCCTTCT GCTGCACACA TTGTTGAAGC TCTGGAAACA
GATGTCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu03043
Accession Version NM_018492.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 969bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product lymphokine-activated killer T-cell-originated protein kinase isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB028500.1 and BC015191.1. On Jul 22, 2013 this sequence version replaced gi:18490990. Summary: This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]. Transcript Variant: This variant (1) represents the longer transcript, and encodes the shorter isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC015191.1, AF237709.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAAGGGA TCAGTAATTT CAAGACACCA AGCAAATTAT CAGAAAAAAA GAAATCTGTA 
TTATGTTCAA CTCCAACTAT AAATATCCCG GCCTCTCCGT TTATGCAGAA GCTTGGCTTT
GGTACTGGGG TAAATGTGTA CCTAATGAAA AGATCTCCAA GAGGTTTGTC TCATTCTCCT
TGGGCTGTAA AAAAGATTAA TCCTATATGT AATGATCATT ATCGAAGTGT GTATCAAAAG
AGACTAATGG ATGAAGCTAA GATTTTGAAA AGCCTTCATC ATCCAAACAT TGTTGGTTAT
CGTGCTTTTA CTGAAGCCAA TGATGGCAGT CTGTGTCTTG CTATGGAATA TGGAGGTGAA
AAGTCTCTAA ATGACTTAAT AGAAGAACGA TATAAAGCCA GCCAAGATCC TTTTCCAGCA
GCCATAATTT TAAAAGTTGC TTTGAATATG GCAAGAGGGT TAAAGTATCT GCACCAAGAA
AAGAAACTGC TTCATGGAGA CATAAAGTCT TCAAATGTTG TAATTAAAGG CGATTTTGAA
ACAATTAAAA TCTGTGATGT AGGAGTCTCT CTACCACTGG ATGAAAATAT GACTGTGACT
GACCCTGAGG CTTGTTACAT TGGCACAGAG CCATGGAAAC CCAAAGAAGC TGTGGAGGAG
AATGGTGTTA TTACTGACAA GGCAGACATA TTTGCCTTTG GCCTTACTTT GTGGGAAATG
ATGACTTTAT CGATTCCACA CATTAATCTT TCAAATGATG ATGATGATGA AGATAAAACT
TTTGATGAAA GTGATTTTGA TGATGAAGCA TACTATGCAG CGTTGGGAAC TAGGCCACCT
ATTAATATGG AAGAACTGGA TGAATCATAC CAGAAAGTAA TTGAACTCTT CTCTGTATGC
ACTAATGAAG ACCCTAAAGA TCGTCCTTCT GCTGCACACA TTGTTGAAGC TCTGGAAACA
GATGTCTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_060962.2
CDS465..1433
Misc Feature(1)279..279(+)
Misc Feature(2)435..437(+)
Misc Feature(3)465..467(+)
Misc Feature(4)489..491(+)
Misc Feature(5)489..491(+)
Misc Feature(6)489..491(+)
Misc Feature(7)519..521(+)
Misc Feature(8)534..536(+)
Misc Feature(9)558..1427(+)
Misc Feature(10)558..560(+)
Misc Feature(11)558..560(+)
Misc Feature(12)564..1412(+)
Misc Feature(13)576..1097(+)
Misc Feature(14)576..1022(+)
Misc Feature(15)588..1097(+)
Misc Feature(16)633..635(+)
Misc Feature(17)639..641(+)
Misc Feature(18)639..641(+)
Misc Feature(19)1017..1097(+)
Misc Feature(20)1422..1430(+)
Exon (1)1..444
Gene:PBK
Gene Synonym:
Exon (2)445..522
Gene:PBK
Gene Synonym:
Exon (3)523..616
Gene:PBK
Gene Synonym:
Exon (4)617..759
Gene:PBK
Gene Synonym:
Exon (5)760..929
Gene:PBK
Gene Synonym:
Exon (6)930..1059
Gene:PBK
Gene Synonym:
Exon (7)1060..1236
Gene:PBK
Gene Synonym:
Exon (8)1237..2117
Gene:PBK
Gene Synonym:
Translation
Position Chain Variation Link
63 63 a, c, g dbSNP:116239149
83 83 a, g dbSNP:573452846
88 88 a, g dbSNP:186272043
90 90 a, g dbSNP:112318817
111 111 c, t dbSNP:759145506
147 147 c, t dbSNP:776002155
155 155 a, c, g dbSNP:543164773
171 171 a, g dbSNP:28407456
177 177 -, c dbSNP:772551082
200 200 a, g dbSNP:180705165
217 217 c, g dbSNP:572331315
221 221 a, g dbSNP:537179694
235 235 a, g dbSNP:144063110
246 246 a, c dbSNP:539738315
264 264 a, t dbSNP:557707522
272 272 a, c dbSNP:772954065
286 286 a, g dbSNP:769179029
290 290 a, g dbSNP:534326554
295 295 c, t dbSNP:565926433
305 305 c, t dbSNP:549049653
314 314 c, t dbSNP:535266291
317 317 a, g dbSNP:369481503
318 318 -, g dbSNP:747064804
359 359 c, g dbSNP:11539583
365 365 a, g dbSNP:3735743
366 366 a, c dbSNP:3735744
371 371 c, g dbSNP:530879259
376 376 a, g dbSNP:776119884
404 404 a, c dbSNP:571668557
410 410 a, g dbSNP:17057972
416 416 g, t dbSNP:200576056
445 445 a, g dbSNP:202051224
468 468 a, g dbSNP:150991972
473 473 a, g dbSNP:368149140
483 483 a, t dbSNP:142678781
498 498 a, g dbSNP:374747017
504 504 c, t dbSNP:749430716
506 506 a, g dbSNP:777701544
511 511 a, g dbSNP:559081825
532 532 c, t dbSNP:114501644
551 551 a, c dbSNP:749465711
553 553 c, t dbSNP:376363789
554 554 a, g dbSNP:769704505
555 555 g, t dbSNP:748711866
556 556 c, t dbSNP:576873768
562 562 c, t dbSNP:755512158
563 563 a, g dbSNP:11539582
575 575 a, g dbSNP:55973425
594 594 -, g dbSNP:745360327
595 595 c, t dbSNP:758139536
596 596 a, g dbSNP:35230929
603 603 c, t dbSNP:199663154
605 605 c, t dbSNP:555099444
610 610 c, t dbSNP:756678174
614 614 a, c dbSNP:373317946
617 617 a, c dbSNP:541416252
618 618 g, t dbSNP:745560003
620 620 g, t dbSNP:778466975
622 622 c, t dbSNP:756909961
623 623 a, g dbSNP:753400716
627 627 a, g dbSNP:763588842
636 636 c, t dbSNP:200725164
642 642 c, t dbSNP:756047700
654 654 a, g dbSNP:201032351
658 658 a, g dbSNP:752572454
667 667 a, c dbSNP:767366634
672 672 c, t dbSNP:367624592
673 673 g, t dbSNP:751339054
681 681 -, cat dbSNP:751279030
685 685 a, t dbSNP:572508534
687 687 c, t dbSNP:555494869
691 691 c, g dbSNP:369154408
693 693 -, gtgt dbSNP:763908468
696 696 c, t dbSNP:112129421
698 698 c, t dbSNP:753244295
706 706 c, g dbSNP:776920066
708 708 c, g dbSNP:768791080
716 716 c, t dbSNP:761280907
724 724 a, t dbSNP:62001048
737 737 c, t dbSNP:772596385
744 744 c, t dbSNP:746263867
745 745 a, t dbSNP:779320923
749 749 a, c dbSNP:770554100
753 753 -, att dbSNP:752618579
757 757 c, t dbSNP:576669630
761 761 c, t dbSNP:772196242
765 765 c, t dbSNP:754938337
766 766 a, g dbSNP:746900679
770 770 g, t dbSNP:779729707
783 783 a, g dbSNP:758222396
784 784 a, g dbSNP:3779620
785 785 c, t dbSNP:764456498
790 790 a, g dbSNP:756387355
797 797 a, g dbSNP:752783878
799 799 a, g dbSNP:373579758
801 801 c, t dbSNP:142068654
803 803 c, t dbSNP:768760254
807 807 a, g dbSNP:766760760
808 808 a, t dbSNP:763346850
810 810 g, t dbSNP:773544696
812 812 a, g dbSNP:769494518
815 815 g, t dbSNP:1675236
818 818 a, g dbSNP:747834390
820 820 g, t dbSNP:185478648
821 821 c, t dbSNP:768158056
825 825 a, g dbSNP:746944771
829 829 c, g dbSNP:780020966
844 844 c, t dbSNP:201842147
852 852 c, t dbSNP:745711431
853 853 a, g dbSNP:371557868
854 854 -, acga dbSNP:761978341
878 878 c, t dbSNP:778842443
881 881 a, c dbSNP:756407655
882 882 c, g dbSNP:752904921
885 885 a, g dbSNP:767514634
888 888 a, g dbSNP:755045401
892 892 c, t dbSNP:751562351
900 900 g, t dbSNP:766921897
904 904 a, c dbSNP:763438217
916 916 c, t dbSNP:556489077
919 919 a, g dbSNP:765520589
931 931 a, g dbSNP:763861092
937 937 a, c dbSNP:760236167
938 938 a, c dbSNP:201933253
947 947 -, gaa dbSNP:770596213
967 967 c, t dbSNP:771646980
981 981 a, g dbSNP:759566784
983 983 -, tgt dbSNP:777299680
984 984 g, t dbSNP:774389423
995 995 c, t dbSNP:770742289
996 996 a, g, t dbSNP:201290873
1002 1002 a, g dbSNP:768990251
1005 1005 a, g dbSNP:747168583
1009 1009 -, ttaa dbSNP:758125261
1009 1009 g, t dbSNP:780122465
1014 1014 a, t dbSNP:758426627
1016 1016 c, t dbSNP:750962230
1024 1024 c, t dbSNP:779518210
1026 1026 c, g dbSNP:757687216
1031 1031 c, g dbSNP:138952065
1033 1033 -, ctct dbSNP:752426328
1035 1035 c, t dbSNP:370697278
1038 1038 a, c dbSNP:200662690
1046 1046 c, t dbSNP:760386214
1051 1051 -, a dbSNP:778811189
1061 1061 a, g dbSNP:767327170
1072 1072 -, g dbSNP:35061575
1105 1105 a, c dbSNP:754663737
1118 1118 a, g dbSNP:751148854
1123 1123 a, g dbSNP:765740749
1124 1124 c, g dbSNP:17057901
1129 1129 a, g dbSNP:772975178
1131 1131 a, g dbSNP:765114169
1133 1133 c, t dbSNP:761639027
1142 1142 c, t dbSNP:369509839
1146 1146 a, g dbSNP:772342394
1148 1148 a, g dbSNP:746019557
1157 1157 -, t dbSNP:758009033
1178 1178 c, g dbSNP:774498834
1184 1184 g, t dbSNP:770864767
1185 1185 a, c dbSNP:36086402
1195 1195 c, t dbSNP:778181131
1196 1196 a, g dbSNP:2272691
1206 1206 a, t dbSNP:748580344
1215 1215 -, t dbSNP:751746598
1218 1218 -, aat dbSNP:764210457
1218 1218 a, g dbSNP:143824466
1222 1222 a, g dbSNP:754682271
1226 1226 c, t dbSNP:751116684
1232 1232 -, tga dbSNP:775693610
1232 1232 g, t dbSNP:765961447
1234 1234 -, tga dbSNP:763304019
1234 1234 a, g dbSNP:116080983
1246 1246 c, t dbSNP:763920061
1256 1256 c, t dbSNP:760422001
1261 1261 -, tt dbSNP:777281564
1273 1273 c, g dbSNP:141116063
1274 1274 a, g dbSNP:766524296
1283 1283 a, c dbSNP:763169761
1285 1285 c, t dbSNP:377305728
1286 1286 a, c, g dbSNP:2294092
1287 1287 c, t dbSNP:777244902
1291 1291 a, g dbSNP:769244420
1305 1305 a, g dbSNP:558321363
1306 1306 g, t dbSNP:780404879
1309 1309 a, c dbSNP:372784235
1312 1312 -, t dbSNP:770504237
1331 1331 -, atca dbSNP:746499746
1333 1333 a, g dbSNP:745525194
1336 1336 a, g dbSNP:778448107
1350 1350 c, t dbSNP:534955062
1354 1354 -, tctct dbSNP:777405490
1358 1358 g, t dbSNP:756731963
1362 1362 c, t dbSNP:753308198
1367 1367 c, t dbSNP:777713260
1372 1372 a, g dbSNP:756023481
1378 1378 -, c dbSNP:771590512
1378 1378 c, t dbSNP:752440460
1379 1379 g, t dbSNP:767340181
1383 1383 g, t dbSNP:763142735
1386 1386 a, c, t dbSNP:765445598
1387 1387 a, g, t dbSNP:776800823
1390 1390 c, t dbSNP:764518967
1392 1392 g, t dbSNP:761173443
1403 1403 c, t dbSNP:775781182
1404 1404 a, g dbSNP:772464104
1405 1405 g, t dbSNP:745563063
1409 1409 c, g, t dbSNP:112670476
1424 1424 a, g dbSNP:770524940
1425 1425 a, g dbSNP:748812180
1427 1427 c, t dbSNP:371650486
1441 1441 c, t dbSNP:777198967
1443 1443 c, g dbSNP:370636900
1449 1449 a, c dbSNP:748104410
1453 1453 c, g dbSNP:780898852
1460 1460 g, t dbSNP:202048382
1461 1461 c, t dbSNP:754770637
1462 1462 a, g dbSNP:1052873
1470 1470 c, g dbSNP:765577188
1472 1472 c, g dbSNP:764168548
1479 1479 c, g dbSNP:757494228
1499 1499 c, t dbSNP:769490128
1510 1510 a, t dbSNP:762797071
1512 1512 c, t dbSNP:548632577
1514 1514 a, g dbSNP:535195013
1530 1530 a, g dbSNP:775171639
1531 1531 c, t dbSNP:569262311
1536 1536 c, g dbSNP:1052874
1585 1585 a, g dbSNP:533243892
1606 1606 a, g dbSNP:182928344
1610 1610 c, t dbSNP:111683270
1643 1643 g, t dbSNP:6986820
1675 1675 c, t dbSNP:527530104
1746 1746 c, t dbSNP:190773208
1750 1750 c, t dbSNP:543118735
1783 1783 a, t dbSNP:115017161
1786 1786 a, t dbSNP:143110122
1845 1845 c, t dbSNP:112744328
1881 1881 c, g dbSNP:578195214
1900 1900 a, c dbSNP:558197709
1947 1947 c, t dbSNP:186276247
1955 1955 -, tt dbSNP:756860081
1969 1969 -, tct dbSNP:397976384
1969 1969 a, t dbSNP:79343602
1970 1970 -, tct dbSNP:72602653
1972 1972 -, ctt, tct dbSNP:60576879
1973 1973 -, ctt dbSNP:149449393
2021 2021 a, g dbSNP:570089943
2046 2046 c, t dbSNP:10092096
2070 2070 a, g dbSNP:145754266
2073 2073 c, t dbSNP:535138327
2114 2114 -, aga dbSNP:57448874
2116 2116 a, g dbSNP:201300164

Target ORF information:

RefSeq Version NM_018492
Organism Homo sapiens (human)
Definition Homo sapiens PDZ binding kinase (PBK), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_018492

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAAGGGA TCAGTAATTT CAAGACACCA AGCAAATTAT CAGAAAAAAA GAAATCTGTA 
TTATGTTCAA CTCCAACTAT AAATATCCCG GCCTCTCCGT TTATGCAGAA GCTTGGCTTT
GGTACTGGGG TAAATGTGTA CCTAATGAAA AGATCTCCAA GAGGTTTGTC TCATTCTCCT
TGGGCTGTAA AAAAGATTAA TCCTATATGT AATGATCATT ATCGAAGTGT GTATCAAAAG
AGACTAATGG ATGAAGCTAA GATTTTGAAA AGCCTTCATC ATCCAAACAT TGTTGGTTAT
CGTGCTTTTA CTGAAGCCAA TGATGGCAGT CTGTGTCTTG CTATGGAATA TGGAGGTGAA
AAGTCTCTAA ATGACTTAAT AGAAGAACGA TATAAAGCCA GCCAAGATCC TTTTCCAGCA
GCCATAATTT TAAAAGTTGC TTTGAATATG GCAAGAGGGT TAAAGTATCT GCACCAAGAA
AAGAAACTGC TTCATGGAGA CATAAAGTCT TCAAATGTTG TAATTAAAGG CGATTTTGAA
ACAATTAAAA TCTGTGATGT AGGAGTCTCT CTACCACTGG ATGAAAATAT GACTGTGACT
GACCCTGAGG CTTGTTACAT TGGCACAGAG CCATGGAAAC CCAAAGAAGC TGTGGAGGAG
AATGGTGTTA TTACTGACAA GGCAGACATA TTTGCCTTTG GCCTTACTTT GTGGGAAATG
ATGACTTTAT CGATTCCACA CATTAATCTT TCAAATGATG ATGATGATGA AGATAAAACT
TTTGATGAAA GTGATTTTGA TGATGAAGCA TACTATGCAG CGTTGGGAAC TAGGCCACCT
ATTAATATGG AAGAACTGGA TGAATCATAC CAGAAAGTAA TTGAACTCTT CTCTGTATGC
ACTAATGAAG ACCCTAAAGA TCGTCCTTCT GCTGCACACA TTGTTGAAGC TCTGGAAACA
GATGTCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu04739
Accession Version NM_001278945.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1002bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product lymphokine-activated killer T-cell-originated protein kinase isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB028500.1, AK301836.1 and BC015191.1. Summary: This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]. Transcript Variant: This variant (2) differs in the 5' UTR, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (2) is longer, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK301836.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA962337 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAAGGGA TCAGTAATTT CAAGACACCA AGCAAATTAT CAGAAAAAAA GAAATCTGTA 
TTATGTTCAA CTCCAACTAT AAATATCCCG GCCTCTCCGT TTATGCAGAA GCTTGGCTTT
GGTACTGGGG TAAATGTGTA CCTAATGAAA AGATCTCCAA GAGGTTTGTC TCATTCTCCT
TGGGCTGTAA AAAAGATTAA TCCTATATGT AATGATCATT ATCGAAGTGT GTATCAAAAG
AGACTAATGG ATGAAGCTAA GATTTTGAAA AGCCTTCATC ATCCAAACAT TGTTGGTTAT
CGTGCTTTTA CTGAAGCCAA TGATGGCAGT CTGTGTCTTG CTATGGAATA TGGAGGTGAA
AAGTCTCTAA ATGACTTAAT AGAAGAACGA TATAAAGCCA GCCAAGATCC TTTTCCAGCA
GCCATAATTT TAAAAGTTGC TTTGAATATG GCAAGAGGGT TAAAGTATCT GCACCAAGAA
AAGAAACTGC TTCATGGAGA CATAAAGTCT TCAAATGTTG TAATTAAAGG CGATTTTGAA
ACAATTAAAA TCTGTGATGT AGGAGTCTCT CTACCACTGG ATGAAAATAT GACTGCTCCT
GCCTTCATAA CCATCTTGCT TGTTTCAGTG ACTGACCCTG AGGCTTGTTA CATTGGCACA
GAGCCATGGA AACCCAAAGA AGCTGTGGAG GAGAATGGTG TTATTACTGA CAAGGCAGAC
ATATTTGCCT TTGGCCTTAC TTTGTGGGAA ATGATGACTT TATCGATTCC ACACATTAAT
CTTTCAAATG ATGATGATGA TGAAGATAAA ACTTTTGATG AAAGTGATTT TGATGATGAA
GCATACTATG CAGCGTTGGG AACTAGGCCA CCTATTAATA TGGAAGAACT GGATGAATCA
TACCAGAAAG TAATTGAACT CTTCTCTGTA TGCACTAATG AAGACCCTAA AGATCGTCCT
TCTGCTGCAC ACATTGTTGA AGCTCTGGAA ACAGATGTCT AG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001265874.1
CDS407..1408
Misc Feature(1)279..279(+)
Misc Feature(2)380..382(+)
Misc Feature(3)500..1402(+)
Misc Feature(4)506..1387(+)
Misc Feature(5)518..1072(+)
Misc Feature(6)518..964(+)
Misc Feature(7)530..1072(+)
Misc Feature(8)959..1072(+)
Exon (1)1..386
Gene:PBK
Gene Synonym:
Exon (2)387..464
Gene:PBK
Gene Synonym:
Exon (3)465..558
Gene:PBK
Gene Synonym:
Exon (4)559..701
Gene:PBK
Gene Synonym:
Exon (5)702..871
Gene:PBK
Gene Synonym:
Exon (6)872..1001
Gene:PBK
Gene Synonym:
Exon (7)1002..1211
Gene:PBK
Gene Synonym:
Exon (8)1212..2092
Gene:PBK
Gene Synonym:
Translation
Position Chain Variation Link
63 63 a, c, g dbSNP:116239149
83 83 a, g dbSNP:573452846
88 88 a, g dbSNP:186272043
90 90 a, g dbSNP:112318817
111 111 c, t dbSNP:759145506
147 147 c, t dbSNP:776002155
155 155 a, c, g dbSNP:543164773
171 171 a, g dbSNP:28407456
177 177 -, c dbSNP:772551082
200 200 a, g dbSNP:180705165
217 217 c, g dbSNP:572331315
221 221 a, g dbSNP:537179694
235 235 a, g dbSNP:144063110
246 246 a, c dbSNP:539738315
264 264 a, t dbSNP:557707522
272 272 a, c dbSNP:772954065
286 286 a, g dbSNP:769179029
290 290 a, g dbSNP:534326554
295 295 c, t dbSNP:565926433
305 305 c, t dbSNP:549049653
314 314 c, t dbSNP:535266291
317 317 a, g dbSNP:369481503
318 318 -, g dbSNP:747064804
359 359 c, g dbSNP:11539583
365 365 a, g dbSNP:3735743
366 366 a, c dbSNP:3735744
371 371 c, g dbSNP:530879259
376 376 a, g dbSNP:776119884
387 387 a, g dbSNP:202051224
410 410 a, g dbSNP:150991972
415 415 a, g dbSNP:368149140
425 425 a, t dbSNP:142678781
440 440 a, g dbSNP:374747017
446 446 c, t dbSNP:749430716
448 448 a, g dbSNP:777701544
453 453 a, g dbSNP:559081825
474 474 c, t dbSNP:114501644
493 493 a, c dbSNP:749465711
495 495 c, t dbSNP:376363789
496 496 a, g dbSNP:769704505
497 497 g, t dbSNP:748711866
498 498 c, t dbSNP:576873768
504 504 c, t dbSNP:755512158
505 505 a, g dbSNP:11539582
517 517 a, g dbSNP:55973425
536 536 -, g dbSNP:745360327
537 537 c, t dbSNP:758139536
538 538 a, g dbSNP:35230929
545 545 c, t dbSNP:199663154
547 547 c, t dbSNP:555099444
552 552 c, t dbSNP:756678174
556 556 a, c dbSNP:373317946
559 559 a, c dbSNP:541416252
560 560 g, t dbSNP:745560003
562 562 g, t dbSNP:778466975
564 564 c, t dbSNP:756909961
565 565 a, g dbSNP:753400716
569 569 a, g dbSNP:763588842
578 578 c, t dbSNP:200725164
584 584 c, t dbSNP:756047700
596 596 a, g dbSNP:201032351
600 600 a, g dbSNP:752572454
609 609 a, c dbSNP:767366634
614 614 c, t dbSNP:367624592
615 615 g, t dbSNP:751339054
623 623 -, cat dbSNP:751279030
627 627 a, t dbSNP:572508534
629 629 c, t dbSNP:555494869
633 633 c, g dbSNP:369154408
635 635 -, gtgt dbSNP:763908468
638 638 c, t dbSNP:112129421
640 640 c, t dbSNP:753244295
648 648 c, g dbSNP:776920066
650 650 c, g dbSNP:768791080
658 658 c, t dbSNP:761280907
666 666 a, t dbSNP:62001048
679 679 c, t dbSNP:772596385
686 686 c, t dbSNP:746263867
687 687 a, t dbSNP:779320923
691 691 a, c dbSNP:770554100
695 695 -, att dbSNP:752618579
699 699 c, t dbSNP:576669630
703 703 c, t dbSNP:772196242
707 707 c, t dbSNP:754938337
708 708 a, g dbSNP:746900679
712 712 g, t dbSNP:779729707
725 725 a, g dbSNP:758222396
726 726 a, g dbSNP:3779620
727 727 c, t dbSNP:764456498
732 732 a, g dbSNP:756387355
739 739 a, g dbSNP:752783878
741 741 a, g dbSNP:373579758
743 743 c, t dbSNP:142068654
745 745 c, t dbSNP:768760254
749 749 a, g dbSNP:766760760
750 750 a, t dbSNP:763346850
752 752 g, t dbSNP:773544696
754 754 a, g dbSNP:769494518
757 757 g, t dbSNP:1675236
760 760 a, g dbSNP:747834390
762 762 g, t dbSNP:185478648
763 763 c, t dbSNP:768158056
767 767 a, g dbSNP:746944771
771 771 c, g dbSNP:780020966
786 786 c, t dbSNP:201842147
794 794 c, t dbSNP:745711431
795 795 a, g dbSNP:371557868
796 796 -, acga dbSNP:761978341
820 820 c, t dbSNP:778842443
823 823 a, c dbSNP:756407655
824 824 c, g dbSNP:752904921
827 827 a, g dbSNP:767514634
830 830 a, g dbSNP:755045401
834 834 c, t dbSNP:751562351
842 842 g, t dbSNP:766921897
846 846 a, c dbSNP:763438217
858 858 c, t dbSNP:556489077
861 861 a, g dbSNP:765520589
873 873 a, g dbSNP:763861092
879 879 a, c dbSNP:760236167
880 880 a, c dbSNP:201933253
889 889 -, gaa dbSNP:770596213
909 909 c, t dbSNP:771646980
923 923 a, g dbSNP:759566784
925 925 -, tgt dbSNP:777299680
926 926 g, t dbSNP:774389423
937 937 c, t dbSNP:770742289
938 938 a, g, t dbSNP:201290873
944 944 a, g dbSNP:768990251
947 947 a, g dbSNP:747168583
951 951 -, ttaa dbSNP:758125261
951 951 g, t dbSNP:780122465
956 956 a, t dbSNP:758426627
958 958 c, t dbSNP:750962230
966 966 c, t dbSNP:779518210
968 968 c, g dbSNP:757687216
973 973 c, g dbSNP:138952065
975 975 -, ctct dbSNP:752426328
977 977 c, t dbSNP:370697278
980 980 a, c dbSNP:200662690
988 988 c, t dbSNP:760386214
993 993 -, a dbSNP:778811189
1008 1008 a, c dbSNP:146146385
1010 1010 g, t dbSNP:374524697
1018 1018 c, t dbSNP:756504082
1022 1022 c, t dbSNP:753079458
1026 1026 a, t dbSNP:771272143
1036 1036 a, g dbSNP:767327170
1047 1047 -, g dbSNP:35061575
1080 1080 a, c dbSNP:754663737
1093 1093 a, g dbSNP:751148854
1098 1098 a, g dbSNP:765740749
1099 1099 c, g dbSNP:17057901
1104 1104 a, g dbSNP:772975178
1106 1106 a, g dbSNP:765114169
1108 1108 c, t dbSNP:761639027
1117 1117 c, t dbSNP:369509839
1121 1121 a, g dbSNP:772342394
1123 1123 a, g dbSNP:746019557
1132 1132 -, t dbSNP:758009033
1153 1153 c, g dbSNP:774498834
1159 1159 g, t dbSNP:770864767
1160 1160 a, c dbSNP:36086402
1170 1170 c, t dbSNP:778181131
1171 1171 a, g dbSNP:2272691
1181 1181 a, t dbSNP:748580344
1190 1190 -, t dbSNP:751746598
1193 1193 -, aat dbSNP:764210457
1193 1193 a, g dbSNP:143824466
1197 1197 a, g dbSNP:754682271
1201 1201 c, t dbSNP:751116684
1207 1207 -, tga dbSNP:775693610
1207 1207 g, t dbSNP:765961447
1209 1209 -, tga dbSNP:763304019
1209 1209 a, g dbSNP:116080983
1221 1221 c, t dbSNP:763920061
1231 1231 c, t dbSNP:760422001
1236 1236 -, tt dbSNP:777281564
1248 1248 c, g dbSNP:141116063
1249 1249 a, g dbSNP:766524296
1258 1258 a, c dbSNP:763169761
1260 1260 c, t dbSNP:377305728
1261 1261 a, c, g dbSNP:2294092
1262 1262 c, t dbSNP:777244902
1266 1266 a, g dbSNP:769244420
1280 1280 a, g dbSNP:558321363
1281 1281 g, t dbSNP:780404879
1284 1284 a, c dbSNP:372784235
1287 1287 -, t dbSNP:770504237
1306 1306 -, atca dbSNP:746499746
1308 1308 a, g dbSNP:745525194
1311 1311 a, g dbSNP:778448107
1325 1325 c, t dbSNP:534955062
1329 1329 -, tctct dbSNP:777405490
1333 1333 g, t dbSNP:756731963
1337 1337 c, t dbSNP:753308198
1342 1342 c, t dbSNP:777713260
1347 1347 a, g dbSNP:756023481
1353 1353 -, c dbSNP:771590512
1353 1353 c, t dbSNP:752440460
1354 1354 g, t dbSNP:767340181
1358 1358 g, t dbSNP:763142735
1361 1361 a, c, t dbSNP:765445598
1362 1362 a, g, t dbSNP:776800823
1365 1365 c, t dbSNP:764518967
1367 1367 g, t dbSNP:761173443
1378 1378 c, t dbSNP:775781182
1379 1379 a, g dbSNP:772464104
1380 1380 g, t dbSNP:745563063
1384 1384 c, g, t dbSNP:112670476
1399 1399 a, g dbSNP:770524940
1400 1400 a, g dbSNP:748812180
1402 1402 c, t dbSNP:371650486
1416 1416 c, t dbSNP:777198967
1418 1418 c, g dbSNP:370636900
1424 1424 a, c dbSNP:748104410
1428 1428 c, g dbSNP:780898852
1435 1435 g, t dbSNP:202048382
1436 1436 c, t dbSNP:754770637
1437 1437 a, g dbSNP:1052873
1445 1445 c, g dbSNP:765577188
1447 1447 c, g dbSNP:764168548
1454 1454 c, g dbSNP:757494228
1474 1474 c, t dbSNP:769490128
1485 1485 a, t dbSNP:762797071
1487 1487 c, t dbSNP:548632577
1489 1489 a, g dbSNP:535195013
1505 1505 a, g dbSNP:775171639
1506 1506 c, t dbSNP:569262311
1511 1511 c, g dbSNP:1052874
1560 1560 a, g dbSNP:533243892
1581 1581 a, g dbSNP:182928344
1585 1585 c, t dbSNP:111683270
1618 1618 g, t dbSNP:6986820
1650 1650 c, t dbSNP:527530104
1721 1721 c, t dbSNP:190773208
1725 1725 c, t dbSNP:543118735
1758 1758 a, t dbSNP:115017161
1761 1761 a, t dbSNP:143110122
1820 1820 c, t dbSNP:112744328
1856 1856 c, g dbSNP:578195214
1875 1875 a, c dbSNP:558197709
1922 1922 c, t dbSNP:186276247
1930 1930 -, tt dbSNP:756860081
1944 1944 -, tct dbSNP:397976384
1944 1944 a, t dbSNP:79343602
1945 1945 -, tct dbSNP:72602653
1947 1947 -, ctt, tct dbSNP:60576879
1948 1948 -, ctt dbSNP:149449393
1996 1996 a, g dbSNP:570089943
2021 2021 c, t dbSNP:10092096
2045 2045 a, g dbSNP:145754266
2048 2048 c, t dbSNP:535138327
2089 2089 -, aga dbSNP:57448874
2091 2091 a, g dbSNP:201300164

Target ORF information:

RefSeq Version NM_001278945
Organism Homo sapiens (human)
Definition Homo sapiens PDZ binding kinase (PBK), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001278945

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGGAAGGGA TCAGTAATTT CAAGACACCA AGCAAATTAT CAGAAAAAAA GAAATCTGTA 
TTATGTTCAA CTCCAACTAT AAATATCCCG GCCTCTCCGT TTATGCAGAA GCTTGGCTTT
GGTACTGGGG TAAATGTGTA CCTAATGAAA AGATCTCCAA GAGGTTTGTC TCATTCTCCT
TGGGCTGTAA AAAAGATTAA TCCTATATGT AATGATCATT ATCGAAGTGT GTATCAAAAG
AGACTAATGG ATGAAGCTAA GATTTTGAAA AGCCTTCATC ATCCAAACAT TGTTGGTTAT
CGTGCTTTTA CTGAAGCCAA TGATGGCAGT CTGTGTCTTG CTATGGAATA TGGAGGTGAA
AAGTCTCTAA ATGACTTAAT AGAAGAACGA TATAAAGCCA GCCAAGATCC TTTTCCAGCA
GCCATAATTT TAAAAGTTGC TTTGAATATG GCAAGAGGGT TAAAGTATCT GCACCAAGAA
AAGAAACTGC TTCATGGAGA CATAAAGTCT TCAAATGTTG TAATTAAAGG CGATTTTGAA
ACAATTAAAA TCTGTGATGT AGGAGTCTCT CTACCACTGG ATGAAAATAT GACTGCTCCT
GCCTTCATAA CCATCTTGCT TGTTTCAGTG ACTGACCCTG AGGCTTGTTA CATTGGCACA
GAGCCATGGA AACCCAAAGA AGCTGTGGAG GAGAATGGTG TTATTACTGA CAAGGCAGAC
ATATTTGCCT TTGGCCTTAC TTTGTGGGAA ATGATGACTT TATCGATTCC ACACATTAAT
CTTTCAAATG ATGATGATGA TGAAGATAAA ACTTTTGATG AAAGTGATTT TGATGATGAA
GCATACTATG CAGCGTTGGG AACTAGGCCA CCTATTAATA TGGAAGAACT GGATGAATCA
TACCAGAAAG TAATTGAACT CTTCTCTGTA TGCACTAATG AAGACCCTAA AGATCGTCCT
TCTGCTGCAC ACATTGTTGA AGCTCTGGAA ACAGATGTCT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.