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PSEN1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol PSEN1
Entrez Gene ID 5663
Full Name presenilin 1
Synonyms AD3, FAD, PS-1, PS1, S182
General protein information
Preferred Names
presenilin-1
Names
presenilin-1
NP_000012.1
NP_015557.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

14

14q24.3

Summary Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene, the full-length nature of only some have been determined. [provided by RefSeq, Aug 2008]. lac of sum
Disorder MIM:

104311

Disorder Html: Alzheimer disease, type 3, 607822 (3); Alzheimer disease, type 3,

mRNA and Protein(s)

mRNA Protein Name
XM_005267864 XP_005267921 presenilin-1 isoform X2
XM_011536971 XP_011535273 presenilin-1 isoform X2
XM_011536972 XP_011535274 presenilin-1 isoform X2
XM_005267866 XP_005267923 presenilin-1 isoform X1
XM_011536973 XP_011535275 presenilin-1 isoform X1
XM_011536974 XP_011535276 presenilin-1 isoform X1
NM_007318 NP_015557 presenilin-1 isoform I-463
NM_000021 NP_000012 presenilin-1 isoform I-467



Homo sapiens (human) PSEN1 NP_000012.1
Pan troglodytes (chimpanzee) PSEN1 XP_001150037.1
Macaca mulatta (Rhesus monkey) PSEN1 XP_001088635.1
Canis lupus familiaris (dog) PSEN1 NP_001002943.1
Bos taurus (cattle) PSEN1 NP_777146.1
Mus musculus (house mouse) Psen1 NP_032969.1
Rattus norvegicus (Norway rat) Psen1 NP_062036.2
Gallus gallus (chicken) PSEN1 NP_989494.1
Danio rerio (zebrafish) psen1 NP_571099.1
Caenorhabditis elegans sel-12 NP_508175.1
Arabidopsis thaliana (thale cress) PS2 NP_180551.1
Arabidopsis thaliana (thale cress) PS1 NP_172346.1
Xenopus (Silurana) tropicalis (western clawed frog) psen1 NP_001027027.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PSEN1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PSEN1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu27909 XM_005267864 PREDICTED: Homo sapiens presenilin 1 (PSEN1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu27909 XM_011536971 PREDICTED: Homo sapiens presenilin 1 (PSEN1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu27909 XM_011536972 PREDICTED: Homo sapiens presenilin 1 (PSEN1), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu27910
XM_005267866 PREDICTED: Homo sapiens presenilin 1 (PSEN1), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu27910
XM_011536973 PREDICTED: Homo sapiens presenilin 1 (PSEN1), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu27910
XM_011536974 PREDICTED: Homo sapiens presenilin 1 (PSEN1), transcript variant X6, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu27910
NM_007318 Homo sapiens presenilin 1 (PSEN1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu27909 NM_000021 Homo sapiens presenilin 1 (PSEN1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu27909
Clone ID Related Accession (Same CDS sequence) NM_000021 , XM_005267864 , XM_011536971 , XM_011536972
Accession Version XM_005267864.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1404bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product presenilin-1 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_026437.13) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACAGAGT TACCTGCACC GTTGTCCTAC TTCCAGAATG CACAGATGTC TGAGGACAAC 
CACCTGAGCA ATACTGTACG TAGCCAGAAT GACAATAGAG AACGGCAGGA GCACAACGAC
AGACGGAGCC TTGGCCACCC TGAGCCATTA TCTAATGGAC GACCCCAGGG TAACTCCCGG
CAGGTGGTGG AGCAAGATGA GGAAGAAGAT GAGGAGCTGA CATTGAAATA TGGCGCCAAG
CATGTGATCA TGCTCTTTGT CCCTGTGACT CTCTGCATGG TGGTGGTCGT GGCTACCATT
AAGTCAGTCA GCTTTTATAC CCGGAAGGAT GGGCAGCTAA TCTATACCCC ATTCACAGAA
GATACCGAGA CTGTGGGCCA GAGAGCCCTG CACTCAATTC TGAATGCTGC CATCATGATC
AGTGTCATTG TTGTCATGAC TATCCTCCTG GTGGTTCTGT ATAAATACAG GTGCTATAAG
GTCATCCATG CCTGGCTTAT TATATCATCT CTATTGTTGC TGTTCTTTTT TTCATTCATT
TACTTGGGGG AAGTGTTTAA AACCTATAAC GTTGCTGTGG ACTACATTAC TGTTGCACTC
CTGATCTGGA ATTTTGGTGT GGTGGGAATG ATTTCCATTC ACTGGAAAGG TCCACTTCGA
CTCCAGCAGG CATATCTCAT TATGATTAGT GCCCTCATGG CCCTGGTGTT TATCAAGTAC
CTCCCTGAAT GGACTGCGTG GCTCATCTTG GCTGTGATTT CAGTATATGA TTTAGTGGCT
GTTTTGTGTC CGAAAGGTCC ACTTCGTATG CTGGTTGAAA CAGCTCAGGA GAGAAATGAA
ACGCTTTTTC CAGCTCTCAT TTACTCCTCA ACAATGGTGT GGTTGGTGAA TATGGCAGAA
GGAGACCCGG AAGCTCAAAG GAGAGTATCC AAAAATTCCA AGTATAATGC AGAAAGCACA
GAAAGGGAGT CACAAGACAC TGTTGCAGAG AATGATGATG GCGGGTTCAG TGAGGAATGG
GAAGCCCAGA GGGACAGTCA TCTAGGGCCT CATCGCTCTA CACCTGAGTC ACGAGCTGCT
GTCCAGGAAC TTTCCAGCAG TATCCTCGCT GGTGAAGACC CAGAGGAAAG GGGAGTAAAA
CTTGGATTGG GAGATTTCAT TTTCTACAGT GTTCTGGTTG GTAAAGCCTC AGCAACAGCC
AGTGGAGACT GGAACACAAC CATAGCCTGT TTCGTAGCCA TATTAATTGG TTTGTGCCTT
ACATTATTAC TCCTTGCCAT TTTCAAGAAA GCATTGCCAG CTCTTCCAAT CTCCATCACC
TTTGGGCTTG TTTTCTACTT TGCCACAGAT TATCTTGTAC AGCCTTTTAT GGACCAATTA
GCATTCCATC AATTTTATAT CTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005267921.1
CDS279..1682
Misc Feature(1)495..1652(+)
Translation

Target ORF information:

RefSeq Version XM_005267864
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens presenilin 1 (PSEN1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005267864

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACAGAGT TACCTGCACC GTTGTCCTAC TTCCAGAATG CACAGATGTC TGAGGACAAC 
CACCTGAGCA ATACTGTACG TAGCCAGAAT GACAATAGAG AACGGCAGGA GCACAACGAC
AGACGGAGCC TTGGCCACCC TGAGCCATTA TCTAATGGAC GACCCCAGGG TAACTCCCGG
CAGGTGGTGG AGCAAGATGA GGAAGAAGAT GAGGAGCTGA CATTGAAATA TGGCGCCAAG
CATGTGATCA TGCTCTTTGT CCCTGTGACT CTCTGCATGG TGGTGGTCGT GGCTACCATT
AAGTCAGTCA GCTTTTATAC CCGGAAGGAT GGGCAGCTAA TCTATACCCC ATTCACAGAA
GATACCGAGA CTGTGGGCCA GAGAGCCCTG CACTCAATTC TGAATGCTGC CATCATGATC
AGTGTCATTG TTGTCATGAC TATCCTCCTG GTGGTTCTGT ATAAATACAG GTGCTATAAG
GTCATCCATG CCTGGCTTAT TATATCATCT CTATTGTTGC TGTTCTTTTT TTCATTCATT
TACTTGGGGG AAGTGTTTAA AACCTATAAC GTTGCTGTGG ACTACATTAC TGTTGCACTC
CTGATCTGGA ATTTTGGTGT GGTGGGAATG ATTTCCATTC ACTGGAAAGG TCCACTTCGA
CTCCAGCAGG CATATCTCAT TATGATTAGT GCCCTCATGG CCCTGGTGTT TATCAAGTAC
CTCCCTGAAT GGACTGCGTG GCTCATCTTG GCTGTGATTT CAGTATATGA TTTAGTGGCT
GTTTTGTGTC CGAAAGGTCC ACTTCGTATG CTGGTTGAAA CAGCTCAGGA GAGAAATGAA
ACGCTTTTTC CAGCTCTCAT TTACTCCTCA ACAATGGTGT GGTTGGTGAA TATGGCAGAA
GGAGACCCGG AAGCTCAAAG GAGAGTATCC AAAAATTCCA AGTATAATGC AGAAAGCACA
GAAAGGGAGT CACAAGACAC TGTTGCAGAG AATGATGATG GCGGGTTCAG TGAGGAATGG
GAAGCCCAGA GGGACAGTCA TCTAGGGCCT CATCGCTCTA CACCTGAGTC ACGAGCTGCT
GTCCAGGAAC TTTCCAGCAG TATCCTCGCT GGTGAAGACC CAGAGGAAAG GGGAGTAAAA
CTTGGATTGG GAGATTTCAT TTTCTACAGT GTTCTGGTTG GTAAAGCCTC AGCAACAGCC
AGTGGAGACT GGAACACAAC CATAGCCTGT TTCGTAGCCA TATTAATTGG TTTGTGCCTT
ACATTATTAC TCCTTGCCAT TTTCAAGAAA GCATTGCCAG CTCTTCCAAT CTCCATCACC
TTTGGGCTTG TTTTCTACTT TGCCACAGAT TATCTTGTAC AGCCTTTTAT GGACCAATTA
GCATTCCATC AATTTTATAT CTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27909
Clone ID Related Accession (Same CDS sequence) NM_000021 , XM_005267864 , XM_011536971 , XM_011536972
Accession Version XM_011536971.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1404bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product presenilin-1 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_026437.13) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACAGAGT TACCTGCACC GTTGTCCTAC TTCCAGAATG CACAGATGTC TGAGGACAAC 
CACCTGAGCA ATACTGTACG TAGCCAGAAT GACAATAGAG AACGGCAGGA GCACAACGAC
AGACGGAGCC TTGGCCACCC TGAGCCATTA TCTAATGGAC GACCCCAGGG TAACTCCCGG
CAGGTGGTGG AGCAAGATGA GGAAGAAGAT GAGGAGCTGA CATTGAAATA TGGCGCCAAG
CATGTGATCA TGCTCTTTGT CCCTGTGACT CTCTGCATGG TGGTGGTCGT GGCTACCATT
AAGTCAGTCA GCTTTTATAC CCGGAAGGAT GGGCAGCTAA TCTATACCCC ATTCACAGAA
GATACCGAGA CTGTGGGCCA GAGAGCCCTG CACTCAATTC TGAATGCTGC CATCATGATC
AGTGTCATTG TTGTCATGAC TATCCTCCTG GTGGTTCTGT ATAAATACAG GTGCTATAAG
GTCATCCATG CCTGGCTTAT TATATCATCT CTATTGTTGC TGTTCTTTTT TTCATTCATT
TACTTGGGGG AAGTGTTTAA AACCTATAAC GTTGCTGTGG ACTACATTAC TGTTGCACTC
CTGATCTGGA ATTTTGGTGT GGTGGGAATG ATTTCCATTC ACTGGAAAGG TCCACTTCGA
CTCCAGCAGG CATATCTCAT TATGATTAGT GCCCTCATGG CCCTGGTGTT TATCAAGTAC
CTCCCTGAAT GGACTGCGTG GCTCATCTTG GCTGTGATTT CAGTATATGA TTTAGTGGCT
GTTTTGTGTC CGAAAGGTCC ACTTCGTATG CTGGTTGAAA CAGCTCAGGA GAGAAATGAA
ACGCTTTTTC CAGCTCTCAT TTACTCCTCA ACAATGGTGT GGTTGGTGAA TATGGCAGAA
GGAGACCCGG AAGCTCAAAG GAGAGTATCC AAAAATTCCA AGTATAATGC AGAAAGCACA
GAAAGGGAGT CACAAGACAC TGTTGCAGAG AATGATGATG GCGGGTTCAG TGAGGAATGG
GAAGCCCAGA GGGACAGTCA TCTAGGGCCT CATCGCTCTA CACCTGAGTC ACGAGCTGCT
GTCCAGGAAC TTTCCAGCAG TATCCTCGCT GGTGAAGACC CAGAGGAAAG GGGAGTAAAA
CTTGGATTGG GAGATTTCAT TTTCTACAGT GTTCTGGTTG GTAAAGCCTC AGCAACAGCC
AGTGGAGACT GGAACACAAC CATAGCCTGT TTCGTAGCCA TATTAATTGG TTTGTGCCTT
ACATTATTAC TCCTTGCCAT TTTCAAGAAA GCATTGCCAG CTCTTCCAAT CTCCATCACC
TTTGGGCTTG TTTTCTACTT TGCCACAGAT TATCTTGTAC AGCCTTTTAT GGACCAATTA
GCATTCCATC AATTTTATAT CTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011535273.1
CDS177..1580
Misc Feature(1)393..1550(+)
Translation

Target ORF information:

RefSeq Version XM_011536971
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens presenilin 1 (PSEN1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011536971

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACAGAGT TACCTGCACC GTTGTCCTAC TTCCAGAATG CACAGATGTC TGAGGACAAC 
CACCTGAGCA ATACTGTACG TAGCCAGAAT GACAATAGAG AACGGCAGGA GCACAACGAC
AGACGGAGCC TTGGCCACCC TGAGCCATTA TCTAATGGAC GACCCCAGGG TAACTCCCGG
CAGGTGGTGG AGCAAGATGA GGAAGAAGAT GAGGAGCTGA CATTGAAATA TGGCGCCAAG
CATGTGATCA TGCTCTTTGT CCCTGTGACT CTCTGCATGG TGGTGGTCGT GGCTACCATT
AAGTCAGTCA GCTTTTATAC CCGGAAGGAT GGGCAGCTAA TCTATACCCC ATTCACAGAA
GATACCGAGA CTGTGGGCCA GAGAGCCCTG CACTCAATTC TGAATGCTGC CATCATGATC
AGTGTCATTG TTGTCATGAC TATCCTCCTG GTGGTTCTGT ATAAATACAG GTGCTATAAG
GTCATCCATG CCTGGCTTAT TATATCATCT CTATTGTTGC TGTTCTTTTT TTCATTCATT
TACTTGGGGG AAGTGTTTAA AACCTATAAC GTTGCTGTGG ACTACATTAC TGTTGCACTC
CTGATCTGGA ATTTTGGTGT GGTGGGAATG ATTTCCATTC ACTGGAAAGG TCCACTTCGA
CTCCAGCAGG CATATCTCAT TATGATTAGT GCCCTCATGG CCCTGGTGTT TATCAAGTAC
CTCCCTGAAT GGACTGCGTG GCTCATCTTG GCTGTGATTT CAGTATATGA TTTAGTGGCT
GTTTTGTGTC CGAAAGGTCC ACTTCGTATG CTGGTTGAAA CAGCTCAGGA GAGAAATGAA
ACGCTTTTTC CAGCTCTCAT TTACTCCTCA ACAATGGTGT GGTTGGTGAA TATGGCAGAA
GGAGACCCGG AAGCTCAAAG GAGAGTATCC AAAAATTCCA AGTATAATGC AGAAAGCACA
GAAAGGGAGT CACAAGACAC TGTTGCAGAG AATGATGATG GCGGGTTCAG TGAGGAATGG
GAAGCCCAGA GGGACAGTCA TCTAGGGCCT CATCGCTCTA CACCTGAGTC ACGAGCTGCT
GTCCAGGAAC TTTCCAGCAG TATCCTCGCT GGTGAAGACC CAGAGGAAAG GGGAGTAAAA
CTTGGATTGG GAGATTTCAT TTTCTACAGT GTTCTGGTTG GTAAAGCCTC AGCAACAGCC
AGTGGAGACT GGAACACAAC CATAGCCTGT TTCGTAGCCA TATTAATTGG TTTGTGCCTT
ACATTATTAC TCCTTGCCAT TTTCAAGAAA GCATTGCCAG CTCTTCCAAT CTCCATCACC
TTTGGGCTTG TTTTCTACTT TGCCACAGAT TATCTTGTAC AGCCTTTTAT GGACCAATTA
GCATTCCATC AATTTTATAT CTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27909
Clone ID Related Accession (Same CDS sequence) NM_000021 , XM_005267864 , XM_011536971 , XM_011536972
Accession Version XM_011536972.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1404bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product presenilin-1 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_026437.13) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACAGAGT TACCTGCACC GTTGTCCTAC TTCCAGAATG CACAGATGTC TGAGGACAAC 
CACCTGAGCA ATACTGTACG TAGCCAGAAT GACAATAGAG AACGGCAGGA GCACAACGAC
AGACGGAGCC TTGGCCACCC TGAGCCATTA TCTAATGGAC GACCCCAGGG TAACTCCCGG
CAGGTGGTGG AGCAAGATGA GGAAGAAGAT GAGGAGCTGA CATTGAAATA TGGCGCCAAG
CATGTGATCA TGCTCTTTGT CCCTGTGACT CTCTGCATGG TGGTGGTCGT GGCTACCATT
AAGTCAGTCA GCTTTTATAC CCGGAAGGAT GGGCAGCTAA TCTATACCCC ATTCACAGAA
GATACCGAGA CTGTGGGCCA GAGAGCCCTG CACTCAATTC TGAATGCTGC CATCATGATC
AGTGTCATTG TTGTCATGAC TATCCTCCTG GTGGTTCTGT ATAAATACAG GTGCTATAAG
GTCATCCATG CCTGGCTTAT TATATCATCT CTATTGTTGC TGTTCTTTTT TTCATTCATT
TACTTGGGGG AAGTGTTTAA AACCTATAAC GTTGCTGTGG ACTACATTAC TGTTGCACTC
CTGATCTGGA ATTTTGGTGT GGTGGGAATG ATTTCCATTC ACTGGAAAGG TCCACTTCGA
CTCCAGCAGG CATATCTCAT TATGATTAGT GCCCTCATGG CCCTGGTGTT TATCAAGTAC
CTCCCTGAAT GGACTGCGTG GCTCATCTTG GCTGTGATTT CAGTATATGA TTTAGTGGCT
GTTTTGTGTC CGAAAGGTCC ACTTCGTATG CTGGTTGAAA CAGCTCAGGA GAGAAATGAA
ACGCTTTTTC CAGCTCTCAT TTACTCCTCA ACAATGGTGT GGTTGGTGAA TATGGCAGAA
GGAGACCCGG AAGCTCAAAG GAGAGTATCC AAAAATTCCA AGTATAATGC AGAAAGCACA
GAAAGGGAGT CACAAGACAC TGTTGCAGAG AATGATGATG GCGGGTTCAG TGAGGAATGG
GAAGCCCAGA GGGACAGTCA TCTAGGGCCT CATCGCTCTA CACCTGAGTC ACGAGCTGCT
GTCCAGGAAC TTTCCAGCAG TATCCTCGCT GGTGAAGACC CAGAGGAAAG GGGAGTAAAA
CTTGGATTGG GAGATTTCAT TTTCTACAGT GTTCTGGTTG GTAAAGCCTC AGCAACAGCC
AGTGGAGACT GGAACACAAC CATAGCCTGT TTCGTAGCCA TATTAATTGG TTTGTGCCTT
ACATTATTAC TCCTTGCCAT TTTCAAGAAA GCATTGCCAG CTCTTCCAAT CTCCATCACC
TTTGGGCTTG TTTTCTACTT TGCCACAGAT TATCTTGTAC AGCCTTTTAT GGACCAATTA
GCATTCCATC AATTTTATAT CTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011535274.1
CDS541..1944
Misc Feature(1)757..1914(+)
Translation

Target ORF information:

RefSeq Version XM_011536972
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens presenilin 1 (PSEN1), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011536972

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACAGAGT TACCTGCACC GTTGTCCTAC TTCCAGAATG CACAGATGTC TGAGGACAAC 
CACCTGAGCA ATACTGTACG TAGCCAGAAT GACAATAGAG AACGGCAGGA GCACAACGAC
AGACGGAGCC TTGGCCACCC TGAGCCATTA TCTAATGGAC GACCCCAGGG TAACTCCCGG
CAGGTGGTGG AGCAAGATGA GGAAGAAGAT GAGGAGCTGA CATTGAAATA TGGCGCCAAG
CATGTGATCA TGCTCTTTGT CCCTGTGACT CTCTGCATGG TGGTGGTCGT GGCTACCATT
AAGTCAGTCA GCTTTTATAC CCGGAAGGAT GGGCAGCTAA TCTATACCCC ATTCACAGAA
GATACCGAGA CTGTGGGCCA GAGAGCCCTG CACTCAATTC TGAATGCTGC CATCATGATC
AGTGTCATTG TTGTCATGAC TATCCTCCTG GTGGTTCTGT ATAAATACAG GTGCTATAAG
GTCATCCATG CCTGGCTTAT TATATCATCT CTATTGTTGC TGTTCTTTTT TTCATTCATT
TACTTGGGGG AAGTGTTTAA AACCTATAAC GTTGCTGTGG ACTACATTAC TGTTGCACTC
CTGATCTGGA ATTTTGGTGT GGTGGGAATG ATTTCCATTC ACTGGAAAGG TCCACTTCGA
CTCCAGCAGG CATATCTCAT TATGATTAGT GCCCTCATGG CCCTGGTGTT TATCAAGTAC
CTCCCTGAAT GGACTGCGTG GCTCATCTTG GCTGTGATTT CAGTATATGA TTTAGTGGCT
GTTTTGTGTC CGAAAGGTCC ACTTCGTATG CTGGTTGAAA CAGCTCAGGA GAGAAATGAA
ACGCTTTTTC CAGCTCTCAT TTACTCCTCA ACAATGGTGT GGTTGGTGAA TATGGCAGAA
GGAGACCCGG AAGCTCAAAG GAGAGTATCC AAAAATTCCA AGTATAATGC AGAAAGCACA
GAAAGGGAGT CACAAGACAC TGTTGCAGAG AATGATGATG GCGGGTTCAG TGAGGAATGG
GAAGCCCAGA GGGACAGTCA TCTAGGGCCT CATCGCTCTA CACCTGAGTC ACGAGCTGCT
GTCCAGGAAC TTTCCAGCAG TATCCTCGCT GGTGAAGACC CAGAGGAAAG GGGAGTAAAA
CTTGGATTGG GAGATTTCAT TTTCTACAGT GTTCTGGTTG GTAAAGCCTC AGCAACAGCC
AGTGGAGACT GGAACACAAC CATAGCCTGT TTCGTAGCCA TATTAATTGG TTTGTGCCTT
ACATTATTAC TCCTTGCCAT TTTCAAGAAA GCATTGCCAG CTCTTCCAAT CTCCATCACC
TTTGGGCTTG TTTTCTACTT TGCCACAGAT TATCTTGTAC AGCCTTTTAT GGACCAATTA
GCATTCCATC AATTTTATAT CTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27910
Clone ID Related Accession (Same CDS sequence) NM_007318 , XM_005267866 , XM_011536973 , XM_011536974
Accession Version XM_005267866.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1392bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product presenilin-1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_026437.13) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACAGAGT TACCTGCACC GTTGTCCTAC TTCCAGAATG CACAGATGTC TGAGGACAAC 
CACCTGAGCA ATACTAATGA CAATAGAGAA CGGCAGGAGC ACAACGACAG ACGGAGCCTT
GGCCACCCTG AGCCATTATC TAATGGACGA CCCCAGGGTA ACTCCCGGCA GGTGGTGGAG
CAAGATGAGG AAGAAGATGA GGAGCTGACA TTGAAATATG GCGCCAAGCA TGTGATCATG
CTCTTTGTCC CTGTGACTCT CTGCATGGTG GTGGTCGTGG CTACCATTAA GTCAGTCAGC
TTTTATACCC GGAAGGATGG GCAGCTAATC TATACCCCAT TCACAGAAGA TACCGAGACT
GTGGGCCAGA GAGCCCTGCA CTCAATTCTG AATGCTGCCA TCATGATCAG TGTCATTGTT
GTCATGACTA TCCTCCTGGT GGTTCTGTAT AAATACAGGT GCTATAAGGT CATCCATGCC
TGGCTTATTA TATCATCTCT ATTGTTGCTG TTCTTTTTTT CATTCATTTA CTTGGGGGAA
GTGTTTAAAA CCTATAACGT TGCTGTGGAC TACATTACTG TTGCACTCCT GATCTGGAAT
TTTGGTGTGG TGGGAATGAT TTCCATTCAC TGGAAAGGTC CACTTCGACT CCAGCAGGCA
TATCTCATTA TGATTAGTGC CCTCATGGCC CTGGTGTTTA TCAAGTACCT CCCTGAATGG
ACTGCGTGGC TCATCTTGGC TGTGATTTCA GTATATGATT TAGTGGCTGT TTTGTGTCCG
AAAGGTCCAC TTCGTATGCT GGTTGAAACA GCTCAGGAGA GAAATGAAAC GCTTTTTCCA
GCTCTCATTT ACTCCTCAAC AATGGTGTGG TTGGTGAATA TGGCAGAAGG AGACCCGGAA
GCTCAAAGGA GAGTATCCAA AAATTCCAAG TATAATGCAG AAAGCACAGA AAGGGAGTCA
CAAGACACTG TTGCAGAGAA TGATGATGGC GGGTTCAGTG AGGAATGGGA AGCCCAGAGG
GACAGTCATC TAGGGCCTCA TCGCTCTACA CCTGAGTCAC GAGCTGCTGT CCAGGAACTT
TCCAGCAGTA TCCTCGCTGG TGAAGACCCA GAGGAAAGGG GAGTAAAACT TGGATTGGGA
GATTTCATTT TCTACAGTGT TCTGGTTGGT AAAGCCTCAG CAACAGCCAG TGGAGACTGG
AACACAACCA TAGCCTGTTT CGTAGCCATA TTAATTGGTT TGTGCCTTAC ATTATTACTC
CTTGCCATTT TCAAGAAAGC ATTGCCAGCT CTTCCAATCT CCATCACCTT TGGGCTTGTT
TTCTACTTTG CCACAGATTA TCTTGTACAG CCTTTTATGG ACCAATTAGC ATTCCATCAA
TTTTATATCT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005267923.1
CDS280..1671
Misc Feature(1)484..1641(+)
Translation

Target ORF information:

RefSeq Version XM_005267866
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens presenilin 1 (PSEN1), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005267866

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACAGAGT TACCTGCACC GTTGTCCTAC TTCCAGAATG CACAGATGTC TGAGGACAAC 
CACCTGAGCA ATACTAATGA CAATAGAGAA CGGCAGGAGC ACAACGACAG ACGGAGCCTT
GGCCACCCTG AGCCATTATC TAATGGACGA CCCCAGGGTA ACTCCCGGCA GGTGGTGGAG
CAAGATGAGG AAGAAGATGA GGAGCTGACA TTGAAATATG GCGCCAAGCA TGTGATCATG
CTCTTTGTCC CTGTGACTCT CTGCATGGTG GTGGTCGTGG CTACCATTAA GTCAGTCAGC
TTTTATACCC GGAAGGATGG GCAGCTAATC TATACCCCAT TCACAGAAGA TACCGAGACT
GTGGGCCAGA GAGCCCTGCA CTCAATTCTG AATGCTGCCA TCATGATCAG TGTCATTGTT
GTCATGACTA TCCTCCTGGT GGTTCTGTAT AAATACAGGT GCTATAAGGT CATCCATGCC
TGGCTTATTA TATCATCTCT ATTGTTGCTG TTCTTTTTTT CATTCATTTA CTTGGGGGAA
GTGTTTAAAA CCTATAACGT TGCTGTGGAC TACATTACTG TTGCACTCCT GATCTGGAAT
TTTGGTGTGG TGGGAATGAT TTCCATTCAC TGGAAAGGTC CACTTCGACT CCAGCAGGCA
TATCTCATTA TGATTAGTGC CCTCATGGCC CTGGTGTTTA TCAAGTACCT CCCTGAATGG
ACTGCGTGGC TCATCTTGGC TGTGATTTCA GTATATGATT TAGTGGCTGT TTTGTGTCCG
AAAGGTCCAC TTCGTATGCT GGTTGAAACA GCTCAGGAGA GAAATGAAAC GCTTTTTCCA
GCTCTCATTT ACTCCTCAAC AATGGTGTGG TTGGTGAATA TGGCAGAAGG AGACCCGGAA
GCTCAAAGGA GAGTATCCAA AAATTCCAAG TATAATGCAG AAAGCACAGA AAGGGAGTCA
CAAGACACTG TTGCAGAGAA TGATGATGGC GGGTTCAGTG AGGAATGGGA AGCCCAGAGG
GACAGTCATC TAGGGCCTCA TCGCTCTACA CCTGAGTCAC GAGCTGCTGT CCAGGAACTT
TCCAGCAGTA TCCTCGCTGG TGAAGACCCA GAGGAAAGGG GAGTAAAACT TGGATTGGGA
GATTTCATTT TCTACAGTGT TCTGGTTGGT AAAGCCTCAG CAACAGCCAG TGGAGACTGG
AACACAACCA TAGCCTGTTT CGTAGCCATA TTAATTGGTT TGTGCCTTAC ATTATTACTC
CTTGCCATTT TCAAGAAAGC ATTGCCAGCT CTTCCAATCT CCATCACCTT TGGGCTTGTT
TTCTACTTTG CCACAGATTA TCTTGTACAG CCTTTTATGG ACCAATTAGC ATTCCATCAA
TTTTATATCT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27910
Clone ID Related Accession (Same CDS sequence) NM_007318 , XM_005267866 , XM_011536973 , XM_011536974
Accession Version XM_011536973.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1392bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product presenilin-1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_026437.13) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACAGAGT TACCTGCACC GTTGTCCTAC TTCCAGAATG CACAGATGTC TGAGGACAAC 
CACCTGAGCA ATACTAATGA CAATAGAGAA CGGCAGGAGC ACAACGACAG ACGGAGCCTT
GGCCACCCTG AGCCATTATC TAATGGACGA CCCCAGGGTA ACTCCCGGCA GGTGGTGGAG
CAAGATGAGG AAGAAGATGA GGAGCTGACA TTGAAATATG GCGCCAAGCA TGTGATCATG
CTCTTTGTCC CTGTGACTCT CTGCATGGTG GTGGTCGTGG CTACCATTAA GTCAGTCAGC
TTTTATACCC GGAAGGATGG GCAGCTAATC TATACCCCAT TCACAGAAGA TACCGAGACT
GTGGGCCAGA GAGCCCTGCA CTCAATTCTG AATGCTGCCA TCATGATCAG TGTCATTGTT
GTCATGACTA TCCTCCTGGT GGTTCTGTAT AAATACAGGT GCTATAAGGT CATCCATGCC
TGGCTTATTA TATCATCTCT ATTGTTGCTG TTCTTTTTTT CATTCATTTA CTTGGGGGAA
GTGTTTAAAA CCTATAACGT TGCTGTGGAC TACATTACTG TTGCACTCCT GATCTGGAAT
TTTGGTGTGG TGGGAATGAT TTCCATTCAC TGGAAAGGTC CACTTCGACT CCAGCAGGCA
TATCTCATTA TGATTAGTGC CCTCATGGCC CTGGTGTTTA TCAAGTACCT CCCTGAATGG
ACTGCGTGGC TCATCTTGGC TGTGATTTCA GTATATGATT TAGTGGCTGT TTTGTGTCCG
AAAGGTCCAC TTCGTATGCT GGTTGAAACA GCTCAGGAGA GAAATGAAAC GCTTTTTCCA
GCTCTCATTT ACTCCTCAAC AATGGTGTGG TTGGTGAATA TGGCAGAAGG AGACCCGGAA
GCTCAAAGGA GAGTATCCAA AAATTCCAAG TATAATGCAG AAAGCACAGA AAGGGAGTCA
CAAGACACTG TTGCAGAGAA TGATGATGGC GGGTTCAGTG AGGAATGGGA AGCCCAGAGG
GACAGTCATC TAGGGCCTCA TCGCTCTACA CCTGAGTCAC GAGCTGCTGT CCAGGAACTT
TCCAGCAGTA TCCTCGCTGG TGAAGACCCA GAGGAAAGGG GAGTAAAACT TGGATTGGGA
GATTTCATTT TCTACAGTGT TCTGGTTGGT AAAGCCTCAG CAACAGCCAG TGGAGACTGG
AACACAACCA TAGCCTGTTT CGTAGCCATA TTAATTGGTT TGTGCCTTAC ATTATTACTC
CTTGCCATTT TCAAGAAAGC ATTGCCAGCT CTTCCAATCT CCATCACCTT TGGGCTTGTT
TTCTACTTTG CCACAGATTA TCTTGTACAG CCTTTTATGG ACCAATTAGC ATTCCATCAA
TTTTATATCT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011535275.1
CDS541..1932
Misc Feature(1)745..1902(+)
Translation

Target ORF information:

RefSeq Version XM_011536973
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens presenilin 1 (PSEN1), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011536973

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACAGAGT TACCTGCACC GTTGTCCTAC TTCCAGAATG CACAGATGTC TGAGGACAAC 
CACCTGAGCA ATACTAATGA CAATAGAGAA CGGCAGGAGC ACAACGACAG ACGGAGCCTT
GGCCACCCTG AGCCATTATC TAATGGACGA CCCCAGGGTA ACTCCCGGCA GGTGGTGGAG
CAAGATGAGG AAGAAGATGA GGAGCTGACA TTGAAATATG GCGCCAAGCA TGTGATCATG
CTCTTTGTCC CTGTGACTCT CTGCATGGTG GTGGTCGTGG CTACCATTAA GTCAGTCAGC
TTTTATACCC GGAAGGATGG GCAGCTAATC TATACCCCAT TCACAGAAGA TACCGAGACT
GTGGGCCAGA GAGCCCTGCA CTCAATTCTG AATGCTGCCA TCATGATCAG TGTCATTGTT
GTCATGACTA TCCTCCTGGT GGTTCTGTAT AAATACAGGT GCTATAAGGT CATCCATGCC
TGGCTTATTA TATCATCTCT ATTGTTGCTG TTCTTTTTTT CATTCATTTA CTTGGGGGAA
GTGTTTAAAA CCTATAACGT TGCTGTGGAC TACATTACTG TTGCACTCCT GATCTGGAAT
TTTGGTGTGG TGGGAATGAT TTCCATTCAC TGGAAAGGTC CACTTCGACT CCAGCAGGCA
TATCTCATTA TGATTAGTGC CCTCATGGCC CTGGTGTTTA TCAAGTACCT CCCTGAATGG
ACTGCGTGGC TCATCTTGGC TGTGATTTCA GTATATGATT TAGTGGCTGT TTTGTGTCCG
AAAGGTCCAC TTCGTATGCT GGTTGAAACA GCTCAGGAGA GAAATGAAAC GCTTTTTCCA
GCTCTCATTT ACTCCTCAAC AATGGTGTGG TTGGTGAATA TGGCAGAAGG AGACCCGGAA
GCTCAAAGGA GAGTATCCAA AAATTCCAAG TATAATGCAG AAAGCACAGA AAGGGAGTCA
CAAGACACTG TTGCAGAGAA TGATGATGGC GGGTTCAGTG AGGAATGGGA AGCCCAGAGG
GACAGTCATC TAGGGCCTCA TCGCTCTACA CCTGAGTCAC GAGCTGCTGT CCAGGAACTT
TCCAGCAGTA TCCTCGCTGG TGAAGACCCA GAGGAAAGGG GAGTAAAACT TGGATTGGGA
GATTTCATTT TCTACAGTGT TCTGGTTGGT AAAGCCTCAG CAACAGCCAG TGGAGACTGG
AACACAACCA TAGCCTGTTT CGTAGCCATA TTAATTGGTT TGTGCCTTAC ATTATTACTC
CTTGCCATTT TCAAGAAAGC ATTGCCAGCT CTTCCAATCT CCATCACCTT TGGGCTTGTT
TTCTACTTTG CCACAGATTA TCTTGTACAG CCTTTTATGG ACCAATTAGC ATTCCATCAA
TTTTATATCT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27910
Clone ID Related Accession (Same CDS sequence) NM_007318 , XM_005267866 , XM_011536973 , XM_011536974
Accession Version XM_011536974.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1392bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product presenilin-1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_026437.13) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACAGAGT TACCTGCACC GTTGTCCTAC TTCCAGAATG CACAGATGTC TGAGGACAAC 
CACCTGAGCA ATACTAATGA CAATAGAGAA CGGCAGGAGC ACAACGACAG ACGGAGCCTT
GGCCACCCTG AGCCATTATC TAATGGACGA CCCCAGGGTA ACTCCCGGCA GGTGGTGGAG
CAAGATGAGG AAGAAGATGA GGAGCTGACA TTGAAATATG GCGCCAAGCA TGTGATCATG
CTCTTTGTCC CTGTGACTCT CTGCATGGTG GTGGTCGTGG CTACCATTAA GTCAGTCAGC
TTTTATACCC GGAAGGATGG GCAGCTAATC TATACCCCAT TCACAGAAGA TACCGAGACT
GTGGGCCAGA GAGCCCTGCA CTCAATTCTG AATGCTGCCA TCATGATCAG TGTCATTGTT
GTCATGACTA TCCTCCTGGT GGTTCTGTAT AAATACAGGT GCTATAAGGT CATCCATGCC
TGGCTTATTA TATCATCTCT ATTGTTGCTG TTCTTTTTTT CATTCATTTA CTTGGGGGAA
GTGTTTAAAA CCTATAACGT TGCTGTGGAC TACATTACTG TTGCACTCCT GATCTGGAAT
TTTGGTGTGG TGGGAATGAT TTCCATTCAC TGGAAAGGTC CACTTCGACT CCAGCAGGCA
TATCTCATTA TGATTAGTGC CCTCATGGCC CTGGTGTTTA TCAAGTACCT CCCTGAATGG
ACTGCGTGGC TCATCTTGGC TGTGATTTCA GTATATGATT TAGTGGCTGT TTTGTGTCCG
AAAGGTCCAC TTCGTATGCT GGTTGAAACA GCTCAGGAGA GAAATGAAAC GCTTTTTCCA
GCTCTCATTT ACTCCTCAAC AATGGTGTGG TTGGTGAATA TGGCAGAAGG AGACCCGGAA
GCTCAAAGGA GAGTATCCAA AAATTCCAAG TATAATGCAG AAAGCACAGA AAGGGAGTCA
CAAGACACTG TTGCAGAGAA TGATGATGGC GGGTTCAGTG AGGAATGGGA AGCCCAGAGG
GACAGTCATC TAGGGCCTCA TCGCTCTACA CCTGAGTCAC GAGCTGCTGT CCAGGAACTT
TCCAGCAGTA TCCTCGCTGG TGAAGACCCA GAGGAAAGGG GAGTAAAACT TGGATTGGGA
GATTTCATTT TCTACAGTGT TCTGGTTGGT AAAGCCTCAG CAACAGCCAG TGGAGACTGG
AACACAACCA TAGCCTGTTT CGTAGCCATA TTAATTGGTT TGTGCCTTAC ATTATTACTC
CTTGCCATTT TCAAGAAAGC ATTGCCAGCT CTTCCAATCT CCATCACCTT TGGGCTTGTT
TTCTACTTTG CCACAGATTA TCTTGTACAG CCTTTTATGG ACCAATTAGC ATTCCATCAA
TTTTATATCT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011535276.1
CDS182..1573
Misc Feature(1)386..1543(+)
Translation

Target ORF information:

RefSeq Version XM_011536974
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens presenilin 1 (PSEN1), transcript variant X6, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011536974

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACAGAGT TACCTGCACC GTTGTCCTAC TTCCAGAATG CACAGATGTC TGAGGACAAC 
CACCTGAGCA ATACTAATGA CAATAGAGAA CGGCAGGAGC ACAACGACAG ACGGAGCCTT
GGCCACCCTG AGCCATTATC TAATGGACGA CCCCAGGGTA ACTCCCGGCA GGTGGTGGAG
CAAGATGAGG AAGAAGATGA GGAGCTGACA TTGAAATATG GCGCCAAGCA TGTGATCATG
CTCTTTGTCC CTGTGACTCT CTGCATGGTG GTGGTCGTGG CTACCATTAA GTCAGTCAGC
TTTTATACCC GGAAGGATGG GCAGCTAATC TATACCCCAT TCACAGAAGA TACCGAGACT
GTGGGCCAGA GAGCCCTGCA CTCAATTCTG AATGCTGCCA TCATGATCAG TGTCATTGTT
GTCATGACTA TCCTCCTGGT GGTTCTGTAT AAATACAGGT GCTATAAGGT CATCCATGCC
TGGCTTATTA TATCATCTCT ATTGTTGCTG TTCTTTTTTT CATTCATTTA CTTGGGGGAA
GTGTTTAAAA CCTATAACGT TGCTGTGGAC TACATTACTG TTGCACTCCT GATCTGGAAT
TTTGGTGTGG TGGGAATGAT TTCCATTCAC TGGAAAGGTC CACTTCGACT CCAGCAGGCA
TATCTCATTA TGATTAGTGC CCTCATGGCC CTGGTGTTTA TCAAGTACCT CCCTGAATGG
ACTGCGTGGC TCATCTTGGC TGTGATTTCA GTATATGATT TAGTGGCTGT TTTGTGTCCG
AAAGGTCCAC TTCGTATGCT GGTTGAAACA GCTCAGGAGA GAAATGAAAC GCTTTTTCCA
GCTCTCATTT ACTCCTCAAC AATGGTGTGG TTGGTGAATA TGGCAGAAGG AGACCCGGAA
GCTCAAAGGA GAGTATCCAA AAATTCCAAG TATAATGCAG AAAGCACAGA AAGGGAGTCA
CAAGACACTG TTGCAGAGAA TGATGATGGC GGGTTCAGTG AGGAATGGGA AGCCCAGAGG
GACAGTCATC TAGGGCCTCA TCGCTCTACA CCTGAGTCAC GAGCTGCTGT CCAGGAACTT
TCCAGCAGTA TCCTCGCTGG TGAAGACCCA GAGGAAAGGG GAGTAAAACT TGGATTGGGA
GATTTCATTT TCTACAGTGT TCTGGTTGGT AAAGCCTCAG CAACAGCCAG TGGAGACTGG
AACACAACCA TAGCCTGTTT CGTAGCCATA TTAATTGGTT TGTGCCTTAC ATTATTACTC
CTTGCCATTT TCAAGAAAGC ATTGCCAGCT CTTCCAATCT CCATCACCTT TGGGCTTGTT
TTCTACTTTG CCACAGATTA TCTTGTACAG CCTTTTATGG ACCAATTAGC ATTCCATCAA
TTTTATATCT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27910
Clone ID Related Accession (Same CDS sequence) NM_007318 , XM_005267866 , XM_011536973 , XM_011536974
Accession Version NM_007318.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1392bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product presenilin-1 isoform I-463
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB203403.1, BC011729.2, DB075605.1, AK094186.1, DA670846.1 and AW069286.1. On Aug 7, 2008 this sequence version replaced gi:7549812. Transcript Variant: This variant (2) uses an alternative donor splice site at one of the coding exons compared to transcript variant 1. It maintains the same reading frame, and encodes a shorter isoform (I-463) missing a 4 aa peptide compared to isoform I-467. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC011729.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACAGAGT TACCTGCACC GTTGTCCTAC TTCCAGAATG CACAGATGTC TGAGGACAAC 
CACCTGAGCA ATACTAATGA CAATAGAGAA CGGCAGGAGC ACAACGACAG ACGGAGCCTT
GGCCACCCTG AGCCATTATC TAATGGACGA CCCCAGGGTA ACTCCCGGCA GGTGGTGGAG
CAAGATGAGG AAGAAGATGA GGAGCTGACA TTGAAATATG GCGCCAAGCA TGTGATCATG
CTCTTTGTCC CTGTGACTCT CTGCATGGTG GTGGTCGTGG CTACCATTAA GTCAGTCAGC
TTTTATACCC GGAAGGATGG GCAGCTAATC TATACCCCAT TCACAGAAGA TACCGAGACT
GTGGGCCAGA GAGCCCTGCA CTCAATTCTG AATGCTGCCA TCATGATCAG TGTCATTGTT
GTCATGACTA TCCTCCTGGT GGTTCTGTAT AAATACAGGT GCTATAAGGT CATCCATGCC
TGGCTTATTA TATCATCTCT ATTGTTGCTG TTCTTTTTTT CATTCATTTA CTTGGGGGAA
GTGTTTAAAA CCTATAACGT TGCTGTGGAC TACATTACTG TTGCACTCCT GATCTGGAAT
TTTGGTGTGG TGGGAATGAT TTCCATTCAC TGGAAAGGTC CACTTCGACT CCAGCAGGCA
TATCTCATTA TGATTAGTGC CCTCATGGCC CTGGTGTTTA TCAAGTACCT CCCTGAATGG
ACTGCGTGGC TCATCTTGGC TGTGATTTCA GTATATGATT TAGTGGCTGT TTTGTGTCCG
AAAGGTCCAC TTCGTATGCT GGTTGAAACA GCTCAGGAGA GAAATGAAAC GCTTTTTCCA
GCTCTCATTT ACTCCTCAAC AATGGTGTGG TTGGTGAATA TGGCAGAAGG AGACCCGGAA
GCTCAAAGGA GAGTATCCAA AAATTCCAAG TATAATGCAG AAAGCACAGA AAGGGAGTCA
CAAGACACTG TTGCAGAGAA TGATGATGGC GGGTTCAGTG AGGAATGGGA AGCCCAGAGG
GACAGTCATC TAGGGCCTCA TCGCTCTACA CCTGAGTCAC GAGCTGCTGT CCAGGAACTT
TCCAGCAGTA TCCTCGCTGG TGAAGACCCA GAGGAAAGGG GAGTAAAACT TGGATTGGGA
GATTTCATTT TCTACAGTGT TCTGGTTGGT AAAGCCTCAG CAACAGCCAG TGGAGACTGG
AACACAACCA TAGCCTGTTT CGTAGCCATA TTAATTGGTT TGTGCCTTAC ATTATTACTC
CTTGCCATTT TCAAGAAAGC ATTGCCAGCT CTTCCAATCT CCATCACCTT TGGGCTTGTT
TTCTACTTTG CCACAGATTA TCTTGTACAG CCTTTTATGG ACCAATTAGC ATTCCATCAA
TTTTATATCT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_015557.2
CDS285..1676
Misc Feature(1)222..224(+)
Misc Feature(2)399..401(+)
Misc Feature(3)489..1646(+)
Misc Feature(4)519..581(+)
Misc Feature(5)669..731(+)
Misc Feature(6)753..815(+)
Misc Feature(7)843..905(+)
Misc Feature(8)933..995(+)
Misc Feature(9)1002..1064(+)
Misc Feature(10)1143..1148(+)
Misc Feature(11)1146..1151(+)
Misc Feature(12)1164..1169(+)
Misc Feature(13)1200..1202(+)
Misc Feature(14)1236..1622(+)
Misc Feature(15)1305..1310(+)
Misc Feature(16)1308..1310(+)
Misc Feature(17)1371..1373(+)
Misc Feature(18)1386..1469(+)
Misc Feature(19)1413..1475(+)
Misc Feature(20)1494..1556(+)
Misc Feature(21)1569..1577(+)
Misc Feature(22)1662..1673(+)
Exon (1)1..149
Gene:PSEN1
Gene Synonym:
Exon (2)150..231
Gene:PSEN1
Gene Synonym:
Exon (3)232..359
Gene:PSEN1
Gene Synonym:
Exon (4)360..610
Gene:PSEN1
Gene Synonym:
Exon (5)611..752
Gene:PSEN1
Gene Synonym:
Exon (6)753..820
Gene:PSEN1
Gene Synonym:
Exon (7)821..1041
Gene:PSEN1
Gene Synonym:
Exon (8)1042..1140
Gene:PSEN1
Gene Synonym:
Exon (9)1141..1227
Gene:PSEN1
Gene Synonym:
Exon (10)1228..1401
Gene:PSEN1
Gene Synonym:
Exon (11)1402..1520
Gene:PSEN1
Gene Synonym:
Exon (12)1521..6078
Gene:PSEN1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_007318
Organism Homo sapiens (human)
Definition Homo sapiens presenilin 1 (PSEN1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_007318

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACAGAGT TACCTGCACC GTTGTCCTAC TTCCAGAATG CACAGATGTC TGAGGACAAC 
CACCTGAGCA ATACTAATGA CAATAGAGAA CGGCAGGAGC ACAACGACAG ACGGAGCCTT
GGCCACCCTG AGCCATTATC TAATGGACGA CCCCAGGGTA ACTCCCGGCA GGTGGTGGAG
CAAGATGAGG AAGAAGATGA GGAGCTGACA TTGAAATATG GCGCCAAGCA TGTGATCATG
CTCTTTGTCC CTGTGACTCT CTGCATGGTG GTGGTCGTGG CTACCATTAA GTCAGTCAGC
TTTTATACCC GGAAGGATGG GCAGCTAATC TATACCCCAT TCACAGAAGA TACCGAGACT
GTGGGCCAGA GAGCCCTGCA CTCAATTCTG AATGCTGCCA TCATGATCAG TGTCATTGTT
GTCATGACTA TCCTCCTGGT GGTTCTGTAT AAATACAGGT GCTATAAGGT CATCCATGCC
TGGCTTATTA TATCATCTCT ATTGTTGCTG TTCTTTTTTT CATTCATTTA CTTGGGGGAA
GTGTTTAAAA CCTATAACGT TGCTGTGGAC TACATTACTG TTGCACTCCT GATCTGGAAT
TTTGGTGTGG TGGGAATGAT TTCCATTCAC TGGAAAGGTC CACTTCGACT CCAGCAGGCA
TATCTCATTA TGATTAGTGC CCTCATGGCC CTGGTGTTTA TCAAGTACCT CCCTGAATGG
ACTGCGTGGC TCATCTTGGC TGTGATTTCA GTATATGATT TAGTGGCTGT TTTGTGTCCG
AAAGGTCCAC TTCGTATGCT GGTTGAAACA GCTCAGGAGA GAAATGAAAC GCTTTTTCCA
GCTCTCATTT ACTCCTCAAC AATGGTGTGG TTGGTGAATA TGGCAGAAGG AGACCCGGAA
GCTCAAAGGA GAGTATCCAA AAATTCCAAG TATAATGCAG AAAGCACAGA AAGGGAGTCA
CAAGACACTG TTGCAGAGAA TGATGATGGC GGGTTCAGTG AGGAATGGGA AGCCCAGAGG
GACAGTCATC TAGGGCCTCA TCGCTCTACA CCTGAGTCAC GAGCTGCTGT CCAGGAACTT
TCCAGCAGTA TCCTCGCTGG TGAAGACCCA GAGGAAAGGG GAGTAAAACT TGGATTGGGA
GATTTCATTT TCTACAGTGT TCTGGTTGGT AAAGCCTCAG CAACAGCCAG TGGAGACTGG
AACACAACCA TAGCCTGTTT CGTAGCCATA TTAATTGGTT TGTGCCTTAC ATTATTACTC
CTTGCCATTT TCAAGAAAGC ATTGCCAGCT CTTCCAATCT CCATCACCTT TGGGCTTGTT
TTCTACTTTG CCACAGATTA TCTTGTACAG CCTTTTATGG ACCAATTAGC ATTCCATCAA
TTTTATATCT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27909
Clone ID Related Accession (Same CDS sequence) NM_000021 , XM_005267864 , XM_011536971 , XM_011536972
Accession Version NM_000021.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1404bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product presenilin-1 isoform I-467
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB203403.1, AK312531.1, BC011729.2, DB075605.1, AK094186.1, DA670846.1 and AW069286.1. This sequence is a reference standard in the RefSeqGene project. On Aug 7, 2008 this sequence version replaced gi:21536454. Transcript Variant: This variant (1) encodes the longer isoform (I-467). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: L42110.1, AK312531.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACAGAGT TACCTGCACC GTTGTCCTAC TTCCAGAATG CACAGATGTC TGAGGACAAC 
CACCTGAGCA ATACTGTACG TAGCCAGAAT GACAATAGAG AACGGCAGGA GCACAACGAC
AGACGGAGCC TTGGCCACCC TGAGCCATTA TCTAATGGAC GACCCCAGGG TAACTCCCGG
CAGGTGGTGG AGCAAGATGA GGAAGAAGAT GAGGAGCTGA CATTGAAATA TGGCGCCAAG
CATGTGATCA TGCTCTTTGT CCCTGTGACT CTCTGCATGG TGGTGGTCGT GGCTACCATT
AAGTCAGTCA GCTTTTATAC CCGGAAGGAT GGGCAGCTAA TCTATACCCC ATTCACAGAA
GATACCGAGA CTGTGGGCCA GAGAGCCCTG CACTCAATTC TGAATGCTGC CATCATGATC
AGTGTCATTG TTGTCATGAC TATCCTCCTG GTGGTTCTGT ATAAATACAG GTGCTATAAG
GTCATCCATG CCTGGCTTAT TATATCATCT CTATTGTTGC TGTTCTTTTT TTCATTCATT
TACTTGGGGG AAGTGTTTAA AACCTATAAC GTTGCTGTGG ACTACATTAC TGTTGCACTC
CTGATCTGGA ATTTTGGTGT GGTGGGAATG ATTTCCATTC ACTGGAAAGG TCCACTTCGA
CTCCAGCAGG CATATCTCAT TATGATTAGT GCCCTCATGG CCCTGGTGTT TATCAAGTAC
CTCCCTGAAT GGACTGCGTG GCTCATCTTG GCTGTGATTT CAGTATATGA TTTAGTGGCT
GTTTTGTGTC CGAAAGGTCC ACTTCGTATG CTGGTTGAAA CAGCTCAGGA GAGAAATGAA
ACGCTTTTTC CAGCTCTCAT TTACTCCTCA ACAATGGTGT GGTTGGTGAA TATGGCAGAA
GGAGACCCGG AAGCTCAAAG GAGAGTATCC AAAAATTCCA AGTATAATGC AGAAAGCACA
GAAAGGGAGT CACAAGACAC TGTTGCAGAG AATGATGATG GCGGGTTCAG TGAGGAATGG
GAAGCCCAGA GGGACAGTCA TCTAGGGCCT CATCGCTCTA CACCTGAGTC ACGAGCTGCT
GTCCAGGAAC TTTCCAGCAG TATCCTCGCT GGTGAAGACC CAGAGGAAAG GGGAGTAAAA
CTTGGATTGG GAGATTTCAT TTTCTACAGT GTTCTGGTTG GTAAAGCCTC AGCAACAGCC
AGTGGAGACT GGAACACAAC CATAGCCTGT TTCGTAGCCA TATTAATTGG TTTGTGCCTT
ACATTATTAC TCCTTGCCAT TTTCAAGAAA GCATTGCCAG CTCTTCCAAT CTCCATCACC
TTTGGGCTTG TTTTCTACTT TGCCACAGAT TATCTTGTAC AGCCTTTTAT GGACCAATTA
GCATTCCATC AATTTTATAT CTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000012.1
CDS285..1688
Misc Feature(1)222..224(+)
Misc Feature(2)411..413(+)
Misc Feature(3)411..413(+)
Misc Feature(4)501..1658(+)
Misc Feature(5)531..593(+)
Misc Feature(6)681..743(+)
Misc Feature(7)765..827(+)
Misc Feature(8)855..917(+)
Misc Feature(9)945..1007(+)
Misc Feature(10)1014..1076(+)
Misc Feature(11)1155..1160(+)
Misc Feature(12)1158..1163(+)
Misc Feature(13)1176..1181(+)
Misc Feature(14)1176..1178(+)
Misc Feature(15)1212..1214(+)
Misc Feature(16)1212..1214(+)
Misc Feature(17)1248..1634(+)
Misc Feature(18)1281..1283(+)
Misc Feature(19)1281..1283(+)
Misc Feature(20)1281..1283(+)
Misc Feature(21)1317..1322(+)
Misc Feature(22)1317..1319(+)
Misc Feature(23)1317..1319(+)
Misc Feature(24)1317..1319(+)
Misc Feature(25)1320..1322(+)
Misc Feature(26)1320..1322(+)
Misc Feature(27)1341..1343(+)
Misc Feature(28)1344..1346(+)
Misc Feature(29)1353..1355(+)
Misc Feature(30)1377..1379(+)
Misc Feature(31)1380..1382(+)
Misc Feature(32)1383..1385(+)
Misc Feature(33)1383..1385(+)
Misc Feature(34)1398..1481(+)
Misc Feature(35)1425..1487(+)
Misc Feature(36)1506..1568(+)
Misc Feature(37)1581..1589(+)
Misc Feature(38)1674..1685(+)
Exon (1)1..149
Gene:PSEN1
Gene Synonym:
Exon (2)150..231
Gene:PSEN1
Gene Synonym:
Exon (3)232..371
Gene:PSEN1
Gene Synonym:
Exon (4)372..622
Gene:PSEN1
Gene Synonym:
Exon (5)623..764
Gene:PSEN1
Gene Synonym:
Exon (6)765..832
Gene:PSEN1
Gene Synonym:
Exon (7)833..1053
Gene:PSEN1
Gene Synonym:
Exon (8)1054..1152
Gene:PSEN1
Gene Synonym:
Exon (9)1153..1239
Gene:PSEN1
Gene Synonym:
Exon (10)1240..1413
Gene:PSEN1
Gene Synonym:
Exon (11)1414..1532
Gene:PSEN1
Gene Synonym:
Exon (12)1533..6090
Gene:PSEN1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000021
Organism Homo sapiens (human)
Definition Homo sapiens presenilin 1 (PSEN1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000021

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGACAGAGT TACCTGCACC GTTGTCCTAC TTCCAGAATG CACAGATGTC TGAGGACAAC 
CACCTGAGCA ATACTGTACG TAGCCAGAAT GACAATAGAG AACGGCAGGA GCACAACGAC
AGACGGAGCC TTGGCCACCC TGAGCCATTA TCTAATGGAC GACCCCAGGG TAACTCCCGG
CAGGTGGTGG AGCAAGATGA GGAAGAAGAT GAGGAGCTGA CATTGAAATA TGGCGCCAAG
CATGTGATCA TGCTCTTTGT CCCTGTGACT CTCTGCATGG TGGTGGTCGT GGCTACCATT
AAGTCAGTCA GCTTTTATAC CCGGAAGGAT GGGCAGCTAA TCTATACCCC ATTCACAGAA
GATACCGAGA CTGTGGGCCA GAGAGCCCTG CACTCAATTC TGAATGCTGC CATCATGATC
AGTGTCATTG TTGTCATGAC TATCCTCCTG GTGGTTCTGT ATAAATACAG GTGCTATAAG
GTCATCCATG CCTGGCTTAT TATATCATCT CTATTGTTGC TGTTCTTTTT TTCATTCATT
TACTTGGGGG AAGTGTTTAA AACCTATAAC GTTGCTGTGG ACTACATTAC TGTTGCACTC
CTGATCTGGA ATTTTGGTGT GGTGGGAATG ATTTCCATTC ACTGGAAAGG TCCACTTCGA
CTCCAGCAGG CATATCTCAT TATGATTAGT GCCCTCATGG CCCTGGTGTT TATCAAGTAC
CTCCCTGAAT GGACTGCGTG GCTCATCTTG GCTGTGATTT CAGTATATGA TTTAGTGGCT
GTTTTGTGTC CGAAAGGTCC ACTTCGTATG CTGGTTGAAA CAGCTCAGGA GAGAAATGAA
ACGCTTTTTC CAGCTCTCAT TTACTCCTCA ACAATGGTGT GGTTGGTGAA TATGGCAGAA
GGAGACCCGG AAGCTCAAAG GAGAGTATCC AAAAATTCCA AGTATAATGC AGAAAGCACA
GAAAGGGAGT CACAAGACAC TGTTGCAGAG AATGATGATG GCGGGTTCAG TGAGGAATGG
GAAGCCCAGA GGGACAGTCA TCTAGGGCCT CATCGCTCTA CACCTGAGTC ACGAGCTGCT
GTCCAGGAAC TTTCCAGCAG TATCCTCGCT GGTGAAGACC CAGAGGAAAG GGGAGTAAAA
CTTGGATTGG GAGATTTCAT TTTCTACAGT GTTCTGGTTG GTAAAGCCTC AGCAACAGCC
AGTGGAGACT GGAACACAAC CATAGCCTGT TTCGTAGCCA TATTAATTGG TTTGTGCCTT
ACATTATTAC TCCTTGCCAT TTTCAAGAAA GCATTGCCAG CTCTTCCAAT CTCCATCACC
TTTGGGCTTG TTTTCTACTT TGCCACAGAT TATCTTGTAC AGCCTTTTAT GGACCAATTA
GCATTCCATC AATTTTATAT CTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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