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PSMA5 proteasome subunit alpha 5 [Homo sapiens (human)]

Gene Symbol PSMA5
Entrez Gene ID 5686
Full Name proteasome subunit alpha 5
Synonyms PSC5, ZETA
General protein information
Preferred Names
proteasome subunit alpha type-5
Names
proteasome subunit alpha type-5
macropain zeta chain
proteasome zeta chain
macropain subunit zeta
proteasome component 5
proteasome subunit zeta
proteasome alpha 5 subunit
multicatalytic endopeptidase complex zeta chain
NP_001186701.1
NP_001186702.1
NP_001186703.1
NP_002781.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p13

Summary The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]. lac of sum
Disorder MIM:

176844

Disorder Html:





The following PSMA5 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PSMA5 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu10419 NM_001199774 Homo sapiens proteasome subunit alpha 5 (PSMA5), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99
OHu10419 NM_001199772 Homo sapiens proteasome subunit alpha 5 (PSMA5), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99
OHu10419 NM_001199773 Homo sapiens proteasome subunit alpha 5 (PSMA5), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$99
OHu11009 NM_002790 Homo sapiens proteasome subunit alpha 5 (PSMA5), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$269

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu10419
Accession Version NM_001199774.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 552bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 14-AUG-2015
Organism Homo sapiens (human)
Product proteasome subunit alpha type-5 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC324021.1, BM793388.1, AL390252.9 and H08369.1. Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]. Transcript Variant: This variant (4) has an alternate 5' UTR exon, resulting in a downstream AUG start codon, as compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BM793388.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
ATGGAGCCCA GCAGCATTGA GAAAATTGTA GAGATTGATG CTCACATAGG TTGTGCCATG 
AGTGGGCTAA TTGCTGATGC TAAGACTTTA ATTGATAAAG CCAGAGTGGA GACACAGAAC
CACTGGTTCA CCTACAATGA GACAATGACA GTGGAGAGTG TGACCCAAGC TGTGTCCAAT
CTGGCTTTGC AGTTTGGAGA AGAAGATGCA GATCCAGGTG CCATGTCTCG TCCCTTTGGA
GTAGCATTAT TATTTGGAGG AGTTGATGAG AAAGGACCCC AGCTGTTTCA TATGGACCCA
TCTGGGACCT TTGTACAGTG TGATGCTCGA GCAATTGGCT CTGCTTCAGA GGGTGCCCAG
AGCTCCTTGC AAGAAGTTTA CCACAAGTCT ATGACTTTGA AAGAAGCCAT CAAGTCTTCA
CTCATCATCC TCAAACAAGT AATGGAGGAG AAGCTGAATG CAACAAACAT TGAGCTAGCC
ACAGTGCAGC CTGGCCAGAA TTTCCACATG TTCACAAAGG AAGAACTTGA AGAGGTTATC
AAGGACATTT AA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001186703.1
CDS213..764
Misc Feature(1)15..17(+)
Misc Feature(2)213..698(+)
Exon (1)1..67
Gene:PSMA5
Gene Synonym:
Exon (2)68..134
Gene:PSMA5
Gene Synonym:
Exon (3)135..261
Gene:PSMA5
Gene Synonym:
Exon (4)262..329
Gene:PSMA5
Gene Synonym:
Exon (5)330..437
Gene:PSMA5
Gene Synonym:
Exon (6)438..496
Gene:PSMA5
Gene Synonym:
Exon (7)497..599
Gene:PSMA5
Gene Synonym:
Exon (8)600..686
Gene:PSMA5
Gene Synonym:
Exon (9)687..3746
Gene:PSMA5
Gene Synonym:
Translation
Position Chain Variation Link
2 2 a, c, t dbSNP:745405004
27 27 c, g dbSNP:534300494
29 29 g, t dbSNP:112340004
58 58 g, t dbSNP:554691744
71 71 c, t dbSNP:768415572
76 76 a, g dbSNP:748920377
85 85 c, t dbSNP:779582683
89 89 c, t dbSNP:372766883
166 166 c, t dbSNP:772397088
203 203 c, t dbSNP:373056949
210 210 c, t dbSNP:768224320
221 221 a, c dbSNP:775150092
222 222 a, g dbSNP:149642021
223 223 c, g dbSNP:139449268
226 226 a, g dbSNP:780559692
230 230 g, t dbSNP:757274389
247 247 c, t dbSNP:368801027
249 249 a, g dbSNP:746895720
270 270 a, g dbSNP:181530546
278 278 c, g dbSNP:7532026
279 279 c, t dbSNP:11544739
299 299 c, t dbSNP:569145241
308 308 a, t dbSNP:772077978
324 324 a, g dbSNP:748022432
349 349 a, g dbSNP:137988825
356 356 a, t dbSNP:776181249
359 359 -, c dbSNP:35552578
362 362 a, g dbSNP:753130651
367 367 a, t dbSNP:760117578
371 371 c, t dbSNP:772781798
391 391 a, g dbSNP:547445834
398 398 g, t dbSNP:567008991
404 404 c, g dbSNP:552813222
433 433 c, t dbSNP:748075392
438 438 g, t dbSNP:775347411
467 467 c, t dbSNP:769973108
482 482 a, g dbSNP:142798786
489 489 c, t dbSNP:746072589
502 502 a, g dbSNP:761418233
503 503 c, t dbSNP:773927613
507 507 a, g dbSNP:764001116
518 518 g, t dbSNP:762939252
541 541 a, g dbSNP:775202158
545 545 a, g dbSNP:143159595
573 573 a, g dbSNP:367924935
584 584 a, g dbSNP:200042225
614 614 a, g dbSNP:369208084
625 625 a, g dbSNP:375404309
631 631 c, t dbSNP:776345861
636 636 a, g dbSNP:771210176
641 641 c, t dbSNP:760874408
647 647 a, g dbSNP:373362735
668 668 c, g dbSNP:772224663
680 680 c, t dbSNP:748126191
690 690 g, t dbSNP:761954163
693 693 a, g dbSNP:774287745
700 700 a, t dbSNP:769340640
729 729 a, c dbSNP:749786389
740 740 a, t dbSNP:780608499
755 755 a, g dbSNP:373874667
760 760 g, t dbSNP:746172507
768 768 a, g dbSNP:777497780
770 770 a, c dbSNP:757922588
781 781 c, g dbSNP:571663193
789 789 c, g dbSNP:778381020
796 796 a, g dbSNP:754958195
801 801 c, t dbSNP:753802907
803 803 a, g dbSNP:766255308
809 809 a, g dbSNP:561671735
816 816 a, c dbSNP:541685340
820 820 -, aaa dbSNP:780095684
887 887 a, g dbSNP:576219262
937 937 a, g dbSNP:556060041
953 953 -, a dbSNP:71593484
958 958 c, t dbSNP:199915183
959 959 -, t dbSNP:11314171
983 983 a, g dbSNP:113853295
1043 1043 c, t dbSNP:537596010
1077 1077 a, g dbSNP:578026701
1106 1106 c, t dbSNP:567171563
1224 1224 c, t dbSNP:7547140
1314 1314 c, t dbSNP:535018905
1315 1315 a, g dbSNP:192565677
1321 1321 a, g dbSNP:7518013
1362 1362 c, t dbSNP:141226547
1366 1366 a, g dbSNP:764204965
1455 1455 a, g dbSNP:187785010
1467 1467 a, g dbSNP:775731882
1505 1505 c, t dbSNP:550100219
1506 1506 a, g dbSNP:10858092
1510 1510 c, t dbSNP:745641441
1543 1543 c, t dbSNP:370236157
1572 1572 -, at dbSNP:565172936
1572 1572 a, c dbSNP:547062979
1584 1584 a, c dbSNP:527304178
1595 1595 c, t dbSNP:758223040
1606 1606 -, t dbSNP:567019111
1608 1608 c, t dbSNP:528532956
1609 1609 a, g dbSNP:750246800
1621 1621 a, g dbSNP:774077017
1641 1641 -, c dbSNP:35299265
1672 1672 a, t dbSNP:78273714
1683 1683 a, g dbSNP:770839854
1714 1714 c, t dbSNP:183300519
1753 1753 a, c dbSNP:749162872
1767 1767 c, t dbSNP:146558711
1792 1792 g, t dbSNP:777721705
1818 1818 g, t dbSNP:545688357
1818 1818 -, t dbSNP:754047225
1819 1819 -, c dbSNP:576286338
1819 1819 c, g dbSNP:762091379
1830 1830 a, t dbSNP:144292582
1894 1894 c, t dbSNP:34696666
1944 1944 a, g dbSNP:755574803
1978 1978 a, g dbSNP:77367788
2025 2025 a, g dbSNP:562316459
2027 2027 a, g dbSNP:377566598
2053 2053 g, t dbSNP:373766464
2069 2069 a, g dbSNP:139640337
2075 2075 a, t dbSNP:113466079
2096 2096 a, t dbSNP:747664272
2106 2106 a, g dbSNP:780870677
2161 2161 g, t dbSNP:754654924
2218 2218 c, t dbSNP:536186117
2237 2237 g, t dbSNP:570265166
2272 2272 a, t dbSNP:556772766
2280 2280 a, c dbSNP:760839293
2350 2350 a, t dbSNP:145806780
2379 2379 a, g dbSNP:775382909
2397 2397 a, g dbSNP:765641493
2405 2405 c, t dbSNP:371841182
2409 2409 c, t dbSNP:757701349
2438 2438 g, t dbSNP:188625234
2475 2475 a, g dbSNP:72703257
2520 2520 a, c, g dbSNP:112763249
2539 2539 c, t dbSNP:567763187
2540 2540 a, g dbSNP:532093382
2562 2562 c, t dbSNP:547865534
2593 2593 a, g dbSNP:774920644
2598 2598 c, t dbSNP:531294939
2602 2602 a, c dbSNP:747854345
2633 2633 a, g dbSNP:149829926
2671 2671 c, t dbSNP:759730811
2679 2679 a, g dbSNP:115680784
2681 2681 a, t dbSNP:74113857
2696 2696 a, c dbSNP:566322725
2716 2716 c, g dbSNP:780963997
2719 2719 a, t dbSNP:560368049
2758 2758 g, t dbSNP:191250921
2786 2786 a, g dbSNP:770643578
2853 2853 c, t dbSNP:185125431
2864 2864 a, t dbSNP:749107447
2873 2873 a, g dbSNP:773114738
2899 2899 a, g dbSNP:558812159
2906 2906 c, t dbSNP:180732219
2937 2937 c, t dbSNP:768386794
2959 2959 a, g dbSNP:150693756
2980 2980 c, t dbSNP:72646546
2997 2997 c, g dbSNP:576359604
2998 2998 g, t dbSNP:556596653
3093 3093 c, t dbSNP:540108374
3156 3156 a, g dbSNP:559476668
3237 3237 -, gtt dbSNP:753310775
3243 3243 -, t dbSNP:565129465
3247 3247 c, t dbSNP:140288007
3268 3268 a, c dbSNP:553941260
3290 3290 a, c dbSNP:189618761
3296 3296 -, gaaa dbSNP:775343043
3342 3342 c, g dbSNP:551501274
3346 3346 c, t dbSNP:540035593
3351 3351 a, g dbSNP:567823676
3368 3368 a, c dbSNP:780625350
3382 3382 a, g dbSNP:548220580
3384 3384 c, t dbSNP:531230258
3408 3408 a, t dbSNP:72646547
3434 3434 a, g dbSNP:72646548
3525 3525 c, t dbSNP:72646549
3548 3548 a, c dbSNP:77675501
3580 3580 g, t dbSNP:72646550
3582 3582 a, c dbSNP:758362228
3619 3619 c, g dbSNP:143506203
3625 3625 -, a dbSNP:745790207
3728 3728 a, t dbSNP:200416322
3734 3734 a, g dbSNP:186400777
3738 3738 -, t dbSNP:537119951

Target ORF information:

RefSeq Version NM_001199774
Organism Homo sapiens (human)
Definition Homo sapiens proteasome subunit alpha 5 (PSMA5), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001199774

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGAGCCCA GCAGCATTGA GAAAATTGTA GAGATTGATG CTCACATAGG TTGTGCCATG 
AGTGGGCTAA TTGCTGATGC TAAGACTTTA ATTGATAAAG CCAGAGTGGA GACACAGAAC
CACTGGTTCA CCTACAATGA GACAATGACA GTGGAGAGTG TGACCCAAGC TGTGTCCAAT
CTGGCTTTGC AGTTTGGAGA AGAAGATGCA GATCCAGGTG CCATGTCTCG TCCCTTTGGA
GTAGCATTAT TATTTGGAGG AGTTGATGAG AAAGGACCCC AGCTGTTTCA TATGGACCCA
TCTGGGACCT TTGTACAGTG TGATGCTCGA GCAATTGGCT CTGCTTCAGA GGGTGCCCAG
AGCTCCTTGC AAGAAGTTTA CCACAAGTCT ATGACTTTGA AAGAAGCCAT CAAGTCTTCA
CTCATCATCC TCAAACAAGT AATGGAGGAG AAGCTGAATG CAACAAACAT TGAGCTAGCC
ACAGTGCAGC CTGGCCAGAA TTTCCACATG TTCACAAAGG AAGAACTTGA AGAGGTTATC
AAGGACATTT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu10419
Accession Version NM_001199772.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 552bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 14-AUG-2015
Organism Homo sapiens (human)
Product proteasome subunit alpha type-5 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC324498.1, AK304448.1, AL390252.9 and H08369.1. Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]. Transcript Variant: This variant (2) lacks an exon in the 5' region, resulting in a downstream AUG start codon, as compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK304448.1, BI548491.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
ATGGAGCCCA GCAGCATTGA GAAAATTGTA GAGATTGATG CTCACATAGG TTGTGCCATG 
AGTGGGCTAA TTGCTGATGC TAAGACTTTA ATTGATAAAG CCAGAGTGGA GACACAGAAC
CACTGGTTCA CCTACAATGA GACAATGACA GTGGAGAGTG TGACCCAAGC TGTGTCCAAT
CTGGCTTTGC AGTTTGGAGA AGAAGATGCA GATCCAGGTG CCATGTCTCG TCCCTTTGGA
GTAGCATTAT TATTTGGAGG AGTTGATGAG AAAGGACCCC AGCTGTTTCA TATGGACCCA
TCTGGGACCT TTGTACAGTG TGATGCTCGA GCAATTGGCT CTGCTTCAGA GGGTGCCCAG
AGCTCCTTGC AAGAAGTTTA CCACAAGTCT ATGACTTTGA AAGAAGCCAT CAAGTCTTCA
CTCATCATCC TCAAACAAGT AATGGAGGAG AAGCTGAATG CAACAAACAT TGAGCTAGCC
ACAGTGCAGC CTGGCCAGAA TTTCCACATG TTCACAAAGG AAGAACTTGA AGAGGTTATC
AAGGACATTT AA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001186701.1
CDS226..777
Misc Feature(1)136..138(+)
Misc Feature(2)226..711(+)
Exon (1)1..147
Gene:PSMA5
Gene Synonym:
Exon (2)148..274
Gene:PSMA5
Gene Synonym:
Exon (3)275..342
Gene:PSMA5
Gene Synonym:
Exon (4)343..450
Gene:PSMA5
Gene Synonym:
Exon (5)451..509
Gene:PSMA5
Gene Synonym:
Exon (6)510..612
Gene:PSMA5
Gene Synonym:
Exon (7)613..699
Gene:PSMA5
Gene Synonym:
Exon (8)700..3759
Gene:PSMA5
Gene Synonym:
Translation
Position Chain Variation Link
20 20 g, t dbSNP:554691744
30 30 g, t dbSNP:563308131
35 35 g, t dbSNP:538220971
39 39 c, g dbSNP:374134883
43 43 c, t dbSNP:545312590
48 48 -, agttgggtgccggtg dbSNP:568267405
54 54 a, g dbSNP:552855417
57 57 c, g dbSNP:532619748
67 67 c, g dbSNP:753287799
68 68 c, g dbSNP:766310334
69 69 c, t dbSNP:760604409
74 74 a, g dbSNP:750278556
80 80 a, g dbSNP:767325616
88 88 c, t dbSNP:761985306
89 89 g, t dbSNP:774670236
91 91 a, g dbSNP:768708394
94 94 c, g dbSNP:1050024
97 97 g, t dbSNP:763104377
101 101 c, t dbSNP:775641035
102 102 c, t dbSNP:770487876
107 107 c, g dbSNP:746362516
113 113 c, t dbSNP:781723154
136 136 g, t dbSNP:566733005
179 179 c, t dbSNP:772397088
216 216 c, t dbSNP:373056949
223 223 c, t dbSNP:768224320
234 234 a, c dbSNP:775150092
235 235 a, g dbSNP:149642021
236 236 c, g dbSNP:139449268
239 239 a, g dbSNP:780559692
243 243 g, t dbSNP:757274389
260 260 c, t dbSNP:368801027
262 262 a, g dbSNP:746895720
283 283 a, g dbSNP:181530546
291 291 c, g dbSNP:7532026
292 292 c, t dbSNP:11544739
312 312 c, t dbSNP:569145241
321 321 a, t dbSNP:772077978
337 337 a, g dbSNP:748022432
362 362 a, g dbSNP:137988825
369 369 a, t dbSNP:776181249
372 372 -, c dbSNP:35552578
375 375 a, g dbSNP:753130651
380 380 a, t dbSNP:760117578
384 384 c, t dbSNP:772781798
404 404 a, g dbSNP:547445834
411 411 g, t dbSNP:567008991
417 417 c, g dbSNP:552813222
446 446 c, t dbSNP:748075392
451 451 g, t dbSNP:775347411
480 480 c, t dbSNP:769973108
495 495 a, g dbSNP:142798786
502 502 c, t dbSNP:746072589
515 515 a, g dbSNP:761418233
516 516 c, t dbSNP:773927613
520 520 a, g dbSNP:764001116
531 531 g, t dbSNP:762939252
554 554 a, g dbSNP:775202158
558 558 a, g dbSNP:143159595
586 586 a, g dbSNP:367924935
597 597 a, g dbSNP:200042225
627 627 a, g dbSNP:369208084
638 638 a, g dbSNP:375404309
644 644 c, t dbSNP:776345861
649 649 a, g dbSNP:771210176
654 654 c, t dbSNP:760874408
660 660 a, g dbSNP:373362735
681 681 c, g dbSNP:772224663
693 693 c, t dbSNP:748126191
703 703 g, t dbSNP:761954163
706 706 a, g dbSNP:774287745
713 713 a, t dbSNP:769340640
742 742 a, c dbSNP:749786389
753 753 a, t dbSNP:780608499
768 768 a, g dbSNP:373874667
773 773 g, t dbSNP:746172507
781 781 a, g dbSNP:777497780
783 783 a, c dbSNP:757922588
794 794 c, g dbSNP:571663193
802 802 c, g dbSNP:778381020
809 809 a, g dbSNP:754958195
814 814 c, t dbSNP:753802907
816 816 a, g dbSNP:766255308
822 822 a, g dbSNP:561671735
829 829 a, c dbSNP:541685340
833 833 -, aaa dbSNP:780095684
900 900 a, g dbSNP:576219262
950 950 a, g dbSNP:556060041
966 966 -, a dbSNP:71593484
971 971 c, t dbSNP:199915183
972 972 -, t dbSNP:11314171
996 996 a, g dbSNP:113853295
1056 1056 c, t dbSNP:537596010
1090 1090 a, g dbSNP:578026701
1119 1119 c, t dbSNP:567171563
1237 1237 c, t dbSNP:7547140
1327 1327 c, t dbSNP:535018905
1328 1328 a, g dbSNP:192565677
1334 1334 a, g dbSNP:7518013
1375 1375 c, t dbSNP:141226547
1379 1379 a, g dbSNP:764204965
1468 1468 a, g dbSNP:187785010
1480 1480 a, g dbSNP:775731882
1518 1518 c, t dbSNP:550100219
1519 1519 a, g dbSNP:10858092
1523 1523 c, t dbSNP:745641441
1556 1556 c, t dbSNP:370236157
1585 1585 -, at dbSNP:565172936
1585 1585 a, c dbSNP:547062979
1597 1597 a, c dbSNP:527304178
1608 1608 c, t dbSNP:758223040
1619 1619 -, t dbSNP:567019111
1621 1621 c, t dbSNP:528532956
1622 1622 a, g dbSNP:750246800
1634 1634 a, g dbSNP:774077017
1654 1654 -, c dbSNP:35299265
1685 1685 a, t dbSNP:78273714
1696 1696 a, g dbSNP:770839854
1727 1727 c, t dbSNP:183300519
1766 1766 a, c dbSNP:749162872
1780 1780 c, t dbSNP:146558711
1805 1805 g, t dbSNP:777721705
1831 1831 g, t dbSNP:545688357
1831 1831 -, t dbSNP:754047225
1832 1832 -, c dbSNP:576286338
1832 1832 c, g dbSNP:762091379
1843 1843 a, t dbSNP:144292582
1907 1907 c, t dbSNP:34696666
1957 1957 a, g dbSNP:755574803
1991 1991 a, g dbSNP:77367788
2038 2038 a, g dbSNP:562316459
2040 2040 a, g dbSNP:377566598
2066 2066 g, t dbSNP:373766464
2082 2082 a, g dbSNP:139640337
2088 2088 a, t dbSNP:113466079
2109 2109 a, t dbSNP:747664272
2119 2119 a, g dbSNP:780870677
2174 2174 g, t dbSNP:754654924
2231 2231 c, t dbSNP:536186117
2250 2250 g, t dbSNP:570265166
2285 2285 a, t dbSNP:556772766
2293 2293 a, c dbSNP:760839293
2363 2363 a, t dbSNP:145806780
2392 2392 a, g dbSNP:775382909
2410 2410 a, g dbSNP:765641493
2418 2418 c, t dbSNP:371841182
2422 2422 c, t dbSNP:757701349
2451 2451 g, t dbSNP:188625234
2488 2488 a, g dbSNP:72703257
2533 2533 a, c, g dbSNP:112763249
2552 2552 c, t dbSNP:567763187
2553 2553 a, g dbSNP:532093382
2575 2575 c, t dbSNP:547865534
2606 2606 a, g dbSNP:774920644
2611 2611 c, t dbSNP:531294939
2615 2615 a, c dbSNP:747854345
2646 2646 a, g dbSNP:149829926
2684 2684 c, t dbSNP:759730811
2692 2692 a, g dbSNP:115680784
2694 2694 a, t dbSNP:74113857
2709 2709 a, c dbSNP:566322725
2729 2729 c, g dbSNP:780963997
2732 2732 a, t dbSNP:560368049
2771 2771 g, t dbSNP:191250921
2799 2799 a, g dbSNP:770643578
2866 2866 c, t dbSNP:185125431
2877 2877 a, t dbSNP:749107447
2886 2886 a, g dbSNP:773114738
2912 2912 a, g dbSNP:558812159
2919 2919 c, t dbSNP:180732219
2950 2950 c, t dbSNP:768386794
2972 2972 a, g dbSNP:150693756
2993 2993 c, t dbSNP:72646546
3010 3010 c, g dbSNP:576359604
3011 3011 g, t dbSNP:556596653
3106 3106 c, t dbSNP:540108374
3169 3169 a, g dbSNP:559476668
3250 3250 -, gtt dbSNP:753310775
3256 3256 -, t dbSNP:565129465
3260 3260 c, t dbSNP:140288007
3281 3281 a, c dbSNP:553941260
3303 3303 a, c dbSNP:189618761
3309 3309 -, gaaa dbSNP:775343043
3355 3355 c, g dbSNP:551501274
3359 3359 c, t dbSNP:540035593
3364 3364 a, g dbSNP:567823676
3381 3381 a, c dbSNP:780625350
3395 3395 a, g dbSNP:548220580
3397 3397 c, t dbSNP:531230258
3421 3421 a, t dbSNP:72646547
3447 3447 a, g dbSNP:72646548
3538 3538 c, t dbSNP:72646549
3561 3561 a, c dbSNP:77675501
3593 3593 g, t dbSNP:72646550
3595 3595 a, c dbSNP:758362228
3632 3632 c, g dbSNP:143506203
3638 3638 -, a dbSNP:745790207
3741 3741 a, t dbSNP:200416322
3747 3747 a, g dbSNP:186400777
3751 3751 -, t dbSNP:537119951

Target ORF information:

RefSeq Version NM_001199772
Organism Homo sapiens (human)
Definition Homo sapiens proteasome subunit alpha 5 (PSMA5), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001199772

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGAGCCCA GCAGCATTGA GAAAATTGTA GAGATTGATG CTCACATAGG TTGTGCCATG 
AGTGGGCTAA TTGCTGATGC TAAGACTTTA ATTGATAAAG CCAGAGTGGA GACACAGAAC
CACTGGTTCA CCTACAATGA GACAATGACA GTGGAGAGTG TGACCCAAGC TGTGTCCAAT
CTGGCTTTGC AGTTTGGAGA AGAAGATGCA GATCCAGGTG CCATGTCTCG TCCCTTTGGA
GTAGCATTAT TATTTGGAGG AGTTGATGAG AAAGGACCCC AGCTGTTTCA TATGGACCCA
TCTGGGACCT TTGTACAGTG TGATGCTCGA GCAATTGGCT CTGCTTCAGA GGGTGCCCAG
AGCTCCTTGC AAGAAGTTTA CCACAAGTCT ATGACTTTGA AAGAAGCCAT CAAGTCTTCA
CTCATCATCC TCAAACAAGT AATGGAGGAG AAGCTGAATG CAACAAACAT TGAGCTAGCC
ACAGTGCAGC CTGGCCAGAA TTTCCACATG TTCACAAAGG AAGAACTTGA AGAGGTTATC
AAGGACATTT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu10419
Accession Version NM_001199773.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 552bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 14-AUG-2015
Organism Homo sapiens (human)
Product proteasome subunit alpha type-5 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI825400.1, AL390252.9 and H08369.1. Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]. Transcript Variant: This variant (3) has an alternate 5' UTR exon, resulting in a downstream AUG start codon, as compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI825400.1, BQ421384.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
ATGGAGCCCA GCAGCATTGA GAAAATTGTA GAGATTGATG CTCACATAGG TTGTGCCATG 
AGTGGGCTAA TTGCTGATGC TAAGACTTTA ATTGATAAAG CCAGAGTGGA GACACAGAAC
CACTGGTTCA CCTACAATGA GACAATGACA GTGGAGAGTG TGACCCAAGC TGTGTCCAAT
CTGGCTTTGC AGTTTGGAGA AGAAGATGCA GATCCAGGTG CCATGTCTCG TCCCTTTGGA
GTAGCATTAT TATTTGGAGG AGTTGATGAG AAAGGACCCC AGCTGTTTCA TATGGACCCA
TCTGGGACCT TTGTACAGTG TGATGCTCGA GCAATTGGCT CTGCTTCAGA GGGTGCCCAG
AGCTCCTTGC AAGAAGTTTA CCACAAGTCT ATGACTTTGA AAGAAGCCAT CAAGTCTTCA
CTCATCATCC TCAAACAAGT AATGGAGGAG AAGCTGAATG CAACAAACAT TGAGCTAGCC
ACAGTGCAGC CTGGCCAGAA TTTCCACATG TTCACAAAGG AAGAACTTGA AGAGGTTATC
AAGGACATTT AA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001186702.1
CDS201..752
Misc Feature(1)42..44(+)
Misc Feature(2)201..686(+)
Exon (1)1..55
Gene:PSMA5
Gene Synonym:
Exon (2)56..122
Gene:PSMA5
Gene Synonym:
Exon (3)123..249
Gene:PSMA5
Gene Synonym:
Exon (4)250..317
Gene:PSMA5
Gene Synonym:
Exon (5)318..425
Gene:PSMA5
Gene Synonym:
Exon (6)426..484
Gene:PSMA5
Gene Synonym:
Exon (7)485..587
Gene:PSMA5
Gene Synonym:
Exon (8)588..674
Gene:PSMA5
Gene Synonym:
Exon (9)675..3734
Gene:PSMA5
Gene Synonym:
Translation
Position Chain Variation Link
2 2 g, t dbSNP:112340004
31 31 g, t dbSNP:554691744
41 41 g, t dbSNP:563308131
46 46 g, t dbSNP:538220971
50 50 c, g dbSNP:374134883
54 54 c, t dbSNP:545312590
59 59 c, t dbSNP:768415572
64 64 a, g dbSNP:748920377
73 73 c, t dbSNP:779582683
77 77 c, t dbSNP:372766883
154 154 c, t dbSNP:772397088
191 191 c, t dbSNP:373056949
198 198 c, t dbSNP:768224320
209 209 a, c dbSNP:775150092
210 210 a, g dbSNP:149642021
211 211 c, g dbSNP:139449268
214 214 a, g dbSNP:780559692
218 218 g, t dbSNP:757274389
235 235 c, t dbSNP:368801027
237 237 a, g dbSNP:746895720
258 258 a, g dbSNP:181530546
266 266 c, g dbSNP:7532026
267 267 c, t dbSNP:11544739
287 287 c, t dbSNP:569145241
296 296 a, t dbSNP:772077978
312 312 a, g dbSNP:748022432
337 337 a, g dbSNP:137988825
344 344 a, t dbSNP:776181249
347 347 -, c dbSNP:35552578
350 350 a, g dbSNP:753130651
355 355 a, t dbSNP:760117578
359 359 c, t dbSNP:772781798
379 379 a, g dbSNP:547445834
386 386 g, t dbSNP:567008991
392 392 c, g dbSNP:552813222
421 421 c, t dbSNP:748075392
426 426 g, t dbSNP:775347411
455 455 c, t dbSNP:769973108
470 470 a, g dbSNP:142798786
477 477 c, t dbSNP:746072589
490 490 a, g dbSNP:761418233
491 491 c, t dbSNP:773927613
495 495 a, g dbSNP:764001116
506 506 g, t dbSNP:762939252
529 529 a, g dbSNP:775202158
533 533 a, g dbSNP:143159595
561 561 a, g dbSNP:367924935
572 572 a, g dbSNP:200042225
602 602 a, g dbSNP:369208084
613 613 a, g dbSNP:375404309
619 619 c, t dbSNP:776345861
624 624 a, g dbSNP:771210176
629 629 c, t dbSNP:760874408
635 635 a, g dbSNP:373362735
656 656 c, g dbSNP:772224663
668 668 c, t dbSNP:748126191
678 678 g, t dbSNP:761954163
681 681 a, g dbSNP:774287745
688 688 a, t dbSNP:769340640
717 717 a, c dbSNP:749786389
728 728 a, t dbSNP:780608499
743 743 a, g dbSNP:373874667
748 748 g, t dbSNP:746172507
756 756 a, g dbSNP:777497780
758 758 a, c dbSNP:757922588
769 769 c, g dbSNP:571663193
777 777 c, g dbSNP:778381020
784 784 a, g dbSNP:754958195
789 789 c, t dbSNP:753802907
791 791 a, g dbSNP:766255308
797 797 a, g dbSNP:561671735
804 804 a, c dbSNP:541685340
808 808 -, aaa dbSNP:780095684
875 875 a, g dbSNP:576219262
925 925 a, g dbSNP:556060041
941 941 -, a dbSNP:71593484
946 946 c, t dbSNP:199915183
947 947 -, t dbSNP:11314171
971 971 a, g dbSNP:113853295
1031 1031 c, t dbSNP:537596010
1065 1065 a, g dbSNP:578026701
1094 1094 c, t dbSNP:567171563
1212 1212 c, t dbSNP:7547140
1302 1302 c, t dbSNP:535018905
1303 1303 a, g dbSNP:192565677
1309 1309 a, g dbSNP:7518013
1350 1350 c, t dbSNP:141226547
1354 1354 a, g dbSNP:764204965
1443 1443 a, g dbSNP:187785010
1455 1455 a, g dbSNP:775731882
1493 1493 c, t dbSNP:550100219
1494 1494 a, g dbSNP:10858092
1498 1498 c, t dbSNP:745641441
1531 1531 c, t dbSNP:370236157
1560 1560 -, at dbSNP:565172936
1560 1560 a, c dbSNP:547062979
1572 1572 a, c dbSNP:527304178
1583 1583 c, t dbSNP:758223040
1594 1594 -, t dbSNP:567019111
1596 1596 c, t dbSNP:528532956
1597 1597 a, g dbSNP:750246800
1609 1609 a, g dbSNP:774077017
1629 1629 -, c dbSNP:35299265
1660 1660 a, t dbSNP:78273714
1671 1671 a, g dbSNP:770839854
1702 1702 c, t dbSNP:183300519
1741 1741 a, c dbSNP:749162872
1755 1755 c, t dbSNP:146558711
1780 1780 g, t dbSNP:777721705
1806 1806 g, t dbSNP:545688357
1806 1806 -, t dbSNP:754047225
1807 1807 -, c dbSNP:576286338
1807 1807 c, g dbSNP:762091379
1818 1818 a, t dbSNP:144292582
1882 1882 c, t dbSNP:34696666
1932 1932 a, g dbSNP:755574803
1966 1966 a, g dbSNP:77367788
2013 2013 a, g dbSNP:562316459
2015 2015 a, g dbSNP:377566598
2041 2041 g, t dbSNP:373766464
2057 2057 a, g dbSNP:139640337
2063 2063 a, t dbSNP:113466079
2084 2084 a, t dbSNP:747664272
2094 2094 a, g dbSNP:780870677
2149 2149 g, t dbSNP:754654924
2206 2206 c, t dbSNP:536186117
2225 2225 g, t dbSNP:570265166
2260 2260 a, t dbSNP:556772766
2268 2268 a, c dbSNP:760839293
2338 2338 a, t dbSNP:145806780
2367 2367 a, g dbSNP:775382909
2385 2385 a, g dbSNP:765641493
2393 2393 c, t dbSNP:371841182
2397 2397 c, t dbSNP:757701349
2426 2426 g, t dbSNP:188625234
2463 2463 a, g dbSNP:72703257
2508 2508 a, c, g dbSNP:112763249
2527 2527 c, t dbSNP:567763187
2528 2528 a, g dbSNP:532093382
2550 2550 c, t dbSNP:547865534
2581 2581 a, g dbSNP:774920644
2586 2586 c, t dbSNP:531294939
2590 2590 a, c dbSNP:747854345
2621 2621 a, g dbSNP:149829926
2659 2659 c, t dbSNP:759730811
2667 2667 a, g dbSNP:115680784
2669 2669 a, t dbSNP:74113857
2684 2684 a, c dbSNP:566322725
2704 2704 c, g dbSNP:780963997
2707 2707 a, t dbSNP:560368049
2746 2746 g, t dbSNP:191250921
2774 2774 a, g dbSNP:770643578
2841 2841 c, t dbSNP:185125431
2852 2852 a, t dbSNP:749107447
2861 2861 a, g dbSNP:773114738
2887 2887 a, g dbSNP:558812159
2894 2894 c, t dbSNP:180732219
2925 2925 c, t dbSNP:768386794
2947 2947 a, g dbSNP:150693756
2968 2968 c, t dbSNP:72646546
2985 2985 c, g dbSNP:576359604
2986 2986 g, t dbSNP:556596653
3081 3081 c, t dbSNP:540108374
3144 3144 a, g dbSNP:559476668
3225 3225 -, gtt dbSNP:753310775
3231 3231 -, t dbSNP:565129465
3235 3235 c, t dbSNP:140288007
3256 3256 a, c dbSNP:553941260
3278 3278 a, c dbSNP:189618761
3284 3284 -, gaaa dbSNP:775343043
3330 3330 c, g dbSNP:551501274
3334 3334 c, t dbSNP:540035593
3339 3339 a, g dbSNP:567823676
3356 3356 a, c dbSNP:780625350
3370 3370 a, g dbSNP:548220580
3372 3372 c, t dbSNP:531230258
3396 3396 a, t dbSNP:72646547
3422 3422 a, g dbSNP:72646548
3513 3513 c, t dbSNP:72646549
3536 3536 a, c dbSNP:77675501
3568 3568 g, t dbSNP:72646550
3570 3570 a, c dbSNP:758362228
3607 3607 c, g dbSNP:143506203
3613 3613 -, a dbSNP:745790207
3716 3716 a, t dbSNP:200416322
3722 3722 a, g dbSNP:186400777
3726 3726 -, t dbSNP:537119951

Target ORF information:

RefSeq Version NM_001199773
Organism Homo sapiens (human)
Definition Homo sapiens proteasome subunit alpha 5 (PSMA5), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001199773

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGAGCCCA GCAGCATTGA GAAAATTGTA GAGATTGATG CTCACATAGG TTGTGCCATG 
AGTGGGCTAA TTGCTGATGC TAAGACTTTA ATTGATAAAG CCAGAGTGGA GACACAGAAC
CACTGGTTCA CCTACAATGA GACAATGACA GTGGAGAGTG TGACCCAAGC TGTGTCCAAT
CTGGCTTTGC AGTTTGGAGA AGAAGATGCA GATCCAGGTG CCATGTCTCG TCCCTTTGGA
GTAGCATTAT TATTTGGAGG AGTTGATGAG AAAGGACCCC AGCTGTTTCA TATGGACCCA
TCTGGGACCT TTGTACAGTG TGATGCTCGA GCAATTGGCT CTGCTTCAGA GGGTGCCCAG
AGCTCCTTGC AAGAAGTTTA CCACAAGTCT ATGACTTTGA AAGAAGCCAT CAAGTCTTCA
CTCATCATCC TCAAACAAGT AATGGAGGAG AAGCTGAATG CAACAAACAT TGAGCTAGCC
ACAGTGCAGC CTGGCCAGAA TTTCCACATG TTCACAAAGG AAGAACTTGA AGAGGTTATC
AAGGACATTT AA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu11009
Accession Version NM_002790.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 726bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 14-AUG-2015
Organism Homo sapiens (human)
Product proteasome subunit alpha type-5 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK313351.1, AK225990.1, AL390252.9 and H08369.1. On Dec 17, 2010 this sequence version replaced gi:23110941. Summary: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]. Transcript Variant: This variant (1) is the predominant transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK313351.1, BC103751.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGTTTCTTA CCCGGTCTGA GTACGACAGG GGCGTGAATA CTTTTTCTCC CGAAGGAAGA 
TTATTTCAAG TGGAATATGC CATTGAGGCT ATCAAGCTTG GTTCTACAGC CATTGGGATC
CAGACATCAG AGGGTGTGTG CCTAGCTGTG GAGAAGAGAA TTACTTCCCC ACTGATGGAG
CCCAGCAGCA TTGAGAAAAT TGTAGAGATT GATGCTCACA TAGGTTGTGC CATGAGTGGG
CTAATTGCTG ATGCTAAGAC TTTAATTGAT AAAGCCAGAG TGGAGACACA GAACCACTGG
TTCACCTACA ATGAGACAAT GACAGTGGAG AGTGTGACCC AAGCTGTGTC CAATCTGGCT
TTGCAGTTTG GAGAAGAAGA TGCAGATCCA GGTGCCATGT CTCGTCCCTT TGGAGTAGCA
TTATTATTTG GAGGAGTTGA TGAGAAAGGA CCCCAGCTGT TTCATATGGA CCCATCTGGG
ACCTTTGTAC AGTGTGATGC TCGAGCAATT GGCTCTGCTT CAGAGGGTGC CCAGAGCTCC
TTGCAAGAAG TTTACCACAA GTCTATGACT TTGAAAGAAG CCATCAAGTC TTCACTCATC
ATCCTCAAAC AAGTAATGGA GGAGAAGCTG AATGCAACAA ACATTGAGCT AGCCACAGTG
CAGCCTGGCC AGAATTTCCA CATGTTCACA AAGGAAGAAC TTGAAGAGGT TATCAAGGAC
ATTTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_002781.2
CDS119..844
Misc Feature(1)92..94(+)
Misc Feature(2)119..121(+)
Misc Feature(3)140..841(+)
Misc Feature(4)140..778(+)
Misc Feature(5)146..619(+)
Misc Feature(6)164..166(+)
Misc Feature(7)164..166(+)
Misc Feature(8)221..634(+)
Misc Feature(9)281..283(+)
Misc Feature(10)281..283(+)
Misc Feature(11)284..286(+)
Misc Feature(12)284..286(+)
Exon (1)1..147
Gene:PSMA5
Gene Synonym:
Exon (2)148..214
Gene:PSMA5
Gene Synonym:
Exon (3)215..341
Gene:PSMA5
Gene Synonym:
Exon (4)342..409
Gene:PSMA5
Gene Synonym:
Exon (5)410..517
Gene:PSMA5
Gene Synonym:
Exon (6)518..576
Gene:PSMA5
Gene Synonym:
Exon (7)577..679
Gene:PSMA5
Gene Synonym:
Exon (8)680..766
Gene:PSMA5
Gene Synonym:
Exon (9)767..3826
Gene:PSMA5
Gene Synonym:
Translation
Position Chain Variation Link
20 20 g, t dbSNP:554691744
30 30 g, t dbSNP:563308131
35 35 g, t dbSNP:538220971
39 39 c, g dbSNP:374134883
43 43 c, t dbSNP:545312590
48 48 -, agttgggtgccggtg dbSNP:568267405
54 54 a, g dbSNP:552855417
57 57 c, g dbSNP:532619748
67 67 c, g dbSNP:753287799
68 68 c, g dbSNP:766310334
69 69 c, t dbSNP:760604409
74 74 a, g dbSNP:750278556
80 80 a, g dbSNP:767325616
88 88 c, t dbSNP:761985306
89 89 g, t dbSNP:774670236
91 91 a, g dbSNP:768708394
94 94 c, g dbSNP:1050024
97 97 g, t dbSNP:763104377
101 101 c, t dbSNP:775641035
102 102 c, t dbSNP:770487876
107 107 c, g dbSNP:746362516
113 113 c, t dbSNP:781723154
136 136 g, t dbSNP:566733005
151 151 c, t dbSNP:768415572
156 156 a, g dbSNP:748920377
165 165 c, t dbSNP:779582683
169 169 c, t dbSNP:372766883
246 246 c, t dbSNP:772397088
283 283 c, t dbSNP:373056949
290 290 c, t dbSNP:768224320
301 301 a, c dbSNP:775150092
302 302 a, g dbSNP:149642021
303 303 c, g dbSNP:139449268
306 306 a, g dbSNP:780559692
310 310 g, t dbSNP:757274389
327 327 c, t dbSNP:368801027
329 329 a, g dbSNP:746895720
350 350 a, g dbSNP:181530546
358 358 c, g dbSNP:7532026
359 359 c, t dbSNP:11544739
379 379 c, t dbSNP:569145241
388 388 a, t dbSNP:772077978
404 404 a, g dbSNP:748022432
429 429 a, g dbSNP:137988825
436 436 a, t dbSNP:776181249
439 439 -, c dbSNP:35552578
442 442 a, g dbSNP:753130651
447 447 a, t dbSNP:760117578
451 451 c, t dbSNP:772781798
471 471 a, g dbSNP:547445834
478 478 g, t dbSNP:567008991
484 484 c, g dbSNP:552813222
513 513 c, t dbSNP:748075392
518 518 g, t dbSNP:775347411
547 547 c, t dbSNP:769973108
562 562 a, g dbSNP:142798786
569 569 c, t dbSNP:746072589
582 582 a, g dbSNP:761418233
583 583 c, t dbSNP:773927613
587 587 a, g dbSNP:764001116
598 598 g, t dbSNP:762939252
621 621 a, g dbSNP:775202158
625 625 a, g dbSNP:143159595
653 653 a, g dbSNP:367924935
664 664 a, g dbSNP:200042225
694 694 a, g dbSNP:369208084
705 705 a, g dbSNP:375404309
711 711 c, t dbSNP:776345861
716 716 a, g dbSNP:771210176
721 721 c, t dbSNP:760874408
727 727 a, g dbSNP:373362735
748 748 c, g dbSNP:772224663
760 760 c, t dbSNP:748126191
770 770 g, t dbSNP:761954163
773 773 a, g dbSNP:774287745
780 780 a, t dbSNP:769340640
809 809 a, c dbSNP:749786389
820 820 a, t dbSNP:780608499
835 835 a, g dbSNP:373874667
840 840 g, t dbSNP:746172507
848 848 a, g dbSNP:777497780
850 850 a, c dbSNP:757922588
861 861 c, g dbSNP:571663193
869 869 c, g dbSNP:778381020
876 876 a, g dbSNP:754958195
881 881 c, t dbSNP:753802907
883 883 a, g dbSNP:766255308
889 889 a, g dbSNP:561671735
896 896 a, c dbSNP:541685340
900 900 -, aaa dbSNP:780095684
967 967 a, g dbSNP:576219262
1017 1017 a, g dbSNP:556060041
1033 1033 -, a dbSNP:71593484
1038 1038 c, t dbSNP:199915183
1039 1039 -, t dbSNP:11314171
1063 1063 a, g dbSNP:113853295
1123 1123 c, t dbSNP:537596010
1157 1157 a, g dbSNP:578026701
1186 1186 c, t dbSNP:567171563
1304 1304 c, t dbSNP:7547140
1394 1394 c, t dbSNP:535018905
1395 1395 a, g dbSNP:192565677
1401 1401 a, g dbSNP:7518013
1442 1442 c, t dbSNP:141226547
1446 1446 a, g dbSNP:764204965
1535 1535 a, g dbSNP:187785010
1547 1547 a, g dbSNP:775731882
1585 1585 c, t dbSNP:550100219
1586 1586 a, g dbSNP:10858092
1590 1590 c, t dbSNP:745641441
1623 1623 c, t dbSNP:370236157
1652 1652 -, at dbSNP:565172936
1652 1652 a, c dbSNP:547062979
1664 1664 a, c dbSNP:527304178
1675 1675 c, t dbSNP:758223040
1686 1686 -, t dbSNP:567019111
1688 1688 c, t dbSNP:528532956
1689 1689 a, g dbSNP:750246800
1701 1701 a, g dbSNP:774077017
1721 1721 -, c dbSNP:35299265
1752 1752 a, t dbSNP:78273714
1763 1763 a, g dbSNP:770839854
1794 1794 c, t dbSNP:183300519
1833 1833 a, c dbSNP:749162872
1847 1847 c, t dbSNP:146558711
1872 1872 g, t dbSNP:777721705
1898 1898 g, t dbSNP:545688357
1898 1898 -, t dbSNP:754047225
1899 1899 -, c dbSNP:576286338
1899 1899 c, g dbSNP:762091379
1910 1910 a, t dbSNP:144292582
1974 1974 c, t dbSNP:34696666
2024 2024 a, g dbSNP:755574803
2058 2058 a, g dbSNP:77367788
2105 2105 a, g dbSNP:562316459
2107 2107 a, g dbSNP:377566598
2133 2133 g, t dbSNP:373766464
2149 2149 a, g dbSNP:139640337
2155 2155 a, t dbSNP:113466079
2176 2176 a, t dbSNP:747664272
2186 2186 a, g dbSNP:780870677
2241 2241 g, t dbSNP:754654924
2298 2298 c, t dbSNP:536186117
2317 2317 g, t dbSNP:570265166
2352 2352 a, t dbSNP:556772766
2360 2360 a, c dbSNP:760839293
2430 2430 a, t dbSNP:145806780
2459 2459 a, g dbSNP:775382909
2477 2477 a, g dbSNP:765641493
2485 2485 c, t dbSNP:371841182
2489 2489 c, t dbSNP:757701349
2518 2518 g, t dbSNP:188625234
2555 2555 a, g dbSNP:72703257
2600 2600 a, c, g dbSNP:112763249
2619 2619 c, t dbSNP:567763187
2620 2620 a, g dbSNP:532093382
2642 2642 c, t dbSNP:547865534
2673 2673 a, g dbSNP:774920644
2678 2678 c, t dbSNP:531294939
2682 2682 a, c dbSNP:747854345
2713 2713 a, g dbSNP:149829926
2751 2751 c, t dbSNP:759730811
2759 2759 a, g dbSNP:115680784
2761 2761 a, t dbSNP:74113857
2776 2776 a, c dbSNP:566322725
2796 2796 c, g dbSNP:780963997
2799 2799 a, t dbSNP:560368049
2838 2838 g, t dbSNP:191250921
2866 2866 a, g dbSNP:770643578
2933 2933 c, t dbSNP:185125431
2944 2944 a, t dbSNP:749107447
2953 2953 a, g dbSNP:773114738
2979 2979 a, g dbSNP:558812159
2986 2986 c, t dbSNP:180732219
3017 3017 c, t dbSNP:768386794
3039 3039 a, g dbSNP:150693756
3060 3060 c, t dbSNP:72646546
3077 3077 c, g dbSNP:576359604
3078 3078 g, t dbSNP:556596653
3173 3173 c, t dbSNP:540108374
3236 3236 a, g dbSNP:559476668
3317 3317 -, gtt dbSNP:753310775
3323 3323 -, t dbSNP:565129465
3327 3327 c, t dbSNP:140288007
3348 3348 a, c dbSNP:553941260
3370 3370 a, c dbSNP:189618761
3376 3376 -, gaaa dbSNP:775343043
3422 3422 c, g dbSNP:551501274
3426 3426 c, t dbSNP:540035593
3431 3431 a, g dbSNP:567823676
3448 3448 a, c dbSNP:780625350
3462 3462 a, g dbSNP:548220580
3464 3464 c, t dbSNP:531230258
3488 3488 a, t dbSNP:72646547
3514 3514 a, g dbSNP:72646548
3605 3605 c, t dbSNP:72646549
3628 3628 a, c dbSNP:77675501
3660 3660 g, t dbSNP:72646550
3662 3662 a, c dbSNP:758362228
3699 3699 c, g dbSNP:143506203
3705 3705 -, a dbSNP:745790207
3808 3808 a, t dbSNP:200416322
3814 3814 a, g dbSNP:186400777
3818 3818 -, t dbSNP:537119951

Target ORF information:

RefSeq Version NM_002790
Organism Homo sapiens (human)
Definition Homo sapiens proteasome subunit alpha 5 (PSMA5), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002790

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGTTTCTTA CCCGGTCTGA GTACGACAGG GGCGTGAATA CTTTTTCTCC CGAAGGAAGA 
TTATTTCAAG TGGAATATGC CATTGAGGCT ATCAAGCTTG GTTCTACAGC CATTGGGATC
CAGACATCAG AGGGTGTGTG CCTAGCTGTG GAGAAGAGAA TTACTTCCCC ACTGATGGAG
CCCAGCAGCA TTGAGAAAAT TGTAGAGATT GATGCTCACA TAGGTTGTGC CATGAGTGGG
CTAATTGCTG ATGCTAAGAC TTTAATTGAT AAAGCCAGAG TGGAGACACA GAACCACTGG
TTCACCTACA ATGAGACAAT GACAGTGGAG AGTGTGACCC AAGCTGTGTC CAATCTGGCT
TTGCAGTTTG GAGAAGAAGA TGCAGATCCA GGTGCCATGT CTCGTCCCTT TGGAGTAGCA
TTATTATTTG GAGGAGTTGA TGAGAAAGGA CCCCAGCTGT TTCATATGGA CCCATCTGGG
ACCTTTGTAC AGTGTGATGC TCGAGCAATT GGCTCTGCTT CAGAGGGTGC CCAGAGCTCC
TTGCAAGAAG TTTACCACAA GTCTATGACT TTGAAAGAAG CCATCAAGTC TTCACTCATC
ATCCTCAAAC AAGTAATGGA GGAGAAGCTG AATGCAACAA ACATTGAGCT AGCCACAGTG
CAGCCTGGCC AGAATTTCCA CATGTTCACA AAGGAAGAAC TTGAAGAGGT TATCAAGGAC
ATTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.