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MAGEE1 melanoma antigen family E1 [Homo sapiens (human)]

Gene Symbol MAGEE1
Entrez Gene ID 57692
Full Name melanoma antigen family E1
Synonyms DAMAGE, HCA1
General protein information
Preferred Names
melanoma-associated antigen E1
Names
melanoma-associated antigen E1
MAGE-E1 antigen
dystrobrevin-associated MAGE protein
hepatocellular carcinoma-associated HCA1
alpha-dystrobrevin-associated MAGE Protein
hepatocellular carcinoma-associated protein 1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xq13.3

Summary This gene encodes an alpha-dystrobrevin-associated MAGE (melanoma-associated antigen) protein, which is a member of the MAGE family. The protein contains a nuclear localization signal in the N-terminus, 30 12-amino acid repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT, and two MAGE domains in the C-terminus. It may play a signaling role in brain, muscle, and peripheral nerve. This gene is located on X chromosome in a region containing loci linked to mental retardation. [provided by RefSeq, Mar 2010]. lac of sum
Disorder MIM:

300759

Disorder Html:





The following MAGEE1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGEE1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu19574 NM_020932 Homo sapiens melanoma antigen family E1 (MAGEE1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD Quote Price

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu19574
Accession Version NM_020932.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2874bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 08-FEB-2015
Organism Homo sapiens (human)
Product melanoma-associated antigen E1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA411859.1, AB046807.1 and BC050588.1. This sequence is a reference standard in the RefSeqGene project. On Mar 13, 2010 this sequence version replaced gi:20143481. Summary: This gene encodes an alpha-dystrobrevin-associated MAGE (melanoma-associated antigen) protein, which is a member of the MAGE family. The protein contains a nuclear localization signal in the N-terminus, 30 12-amino acid repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT, and two MAGE domains in the C-terminus. It may play a signaling role in brain, muscle, and peripheral nerve. This gene is located on X chromosome in a region containing loci linked to mental retardation. [provided by RefSeq, Mar 2010].

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGTCTCTGG TAAGCCAGAA TTCGCGCCGC CGCCGCCGCC GCGTTGCAAA GGCTACTGCG 
CACAACAGCA GCTGGGGCGA AATGCAGGCC CCTAATGCCC CCGGTCTCCC CGCTGATGTG
CCAGGCTCAG ACGTCCCCCA GGGTCCCAGC GATTCCCAGA TCCTCCAGGG CCTCTGCGCC
TCTGAGGGCC CAAGCACCTC CGTTCTGCCC ACCTCCGCTG AGGGCCCAAG CACCTTTGTG
CCGCCCACCA TCTCTGAGGC CTCAAGCGCC TCCGGGCAGC CCACCATCTC TGAGGGACCT
GGCACCTCCG TGCTGCCCAC CCCCAGTGAG GGCCTAAGCA CCTCCGGGCC TCCCACCATC
TCTAAGGGGC TGTGCACCTC TGTGACGCTT GCCGCCTCTG AGGGCCGGAA CACCTCCAGG
CCGCCCACTT CCTCTGAGGA ACCTAGCACC TCCGTGCCGC CCACCGCCTC TGAGGTACCG
AGCACCTCCC TGCCGCCCAC CCCTGGTGAG GGAACGAGCA CCTCCGTGCC GCCCACAGCC
TATGAGGGAC CAAGCACCTC CGTGGTGCCC ACCCCTGATG AGGGACCAAG CACCTCCGTG
CTGCCTACAC CTGGTGAGGG ACCAGGCACC TCCGTGCCGC TCGCCGCCAC TGAGGGCCTG
AGCACCTCCG TGCAGGCCAC TCCTGATGAG GGACCGAGCA CCTCCGTGCC GCCCACCGCC
ACTGAGGGCC TAAGCACCCC CGTGCCACCC ACCCGTGATG AGGGACCGAG CACCTCCGTG
CCGGCCACTC CTGGTGAGGG ACCGAGCACC TCCGTGCTGC CCGCCGCCTC TGACGGACAA
AGCATCTCCT TGGTGCCCAC CCGCGGTAAG GGATCAAGCA CCTCCGTGCC CCCCACCGCC
ACCGAGGGCC TGAGCACCTC CGTGCAGCCC ACTGCTGGTG AGGGATCGAG CACCTCCGTG
CCGCCCACCC CTGGTGGGGG ACTGAGCACC TCCGTGCCGC CCACCGCCAC TGAGGAGTTG
AGCACCTCCG TGCCGCCCAC TCCCGGTGAG GGACCAAGCA CTTCCGTACT GCCAATCCCC
GGTGAGGGAC TGAGCACCTC TGTGCCGCCC ACCGCCTCTG ATGGATCGGA CACCTCCGTG
CCGCCCACTC CTGGTGAGGG CGCAAGCACC TTAGTGCAGC CCACCGCCCC TGACGGACCG
GGAAGCTCCG TGCTGCCTAA CCCTGGTGAG GGCCCGAGCA CATTGTTTAG CTCTAGTGCT
TCTGTGGACC GGAACCCCTC CAAGTGTTCC CTTGTTTTGC CAAGCCCTAG GGTAACCAAG
GCCTCCGTGG ACTCAGATTC TGAGGGTCCT AAGGGTGCAG AAGGCCCTAT AGAATTCGAG
GTCCTGAGAG ACTGTGAGAG CCCCAACTCC ATTAGTATTA TGGGCCTCAA TACTTCCCGG
GTTGCAATTA CCCTGAAGCC CCAAGACCCT ATGGAACAGA ACGTAGCTGA GCTGTTGCAG
TTCCTGCTGG TGAAGGATCA GAGCAAGTAC CCTATCCGGG AGTCTGAAAT GCGGGAATAT
ATTGTTAAAG AATATCGCAA CCAGTTTCCT GAGATACTCA GGCGAGCAGC AGCCCACCTG
GAGTGCATTT TTAGGTTTGA ATTGAGAGAA CTTGACCCTG AGGCACACAC CTACATTCTG
TTAAACAAAC TGGGACCTGT GCCCTTTGAA GGGTTAGAAG AGAGCCCAAA TGGGCCAAAG
ATGGGCCTCC TGATGATGAT TCTAGGCCAA ATATTCCTGA ATGGCAACCA AGCCAAGGAG
GCTGAGATTT GGGAAATGCT CTGGAGGATG GGGGTGCAGC GGGAAAGGAG GCTTTCCATT
TTTGGGAACC CAAAGAGACT TCTGTCTGTG GAGTTTGTAT GGCAGCGTTA CTTAGACTAC
AGGCCAGTAA CTGACTGTAA ACCAGTGGAG TATGAGTTTT TCTGGGGCCC AAGATCCCAC
CTAGAAACCA CCAAGATGAA AATTCTGAAG TTCATGGCGA AAATATATAA CAAAGATCCT
ATGGATTGGC CAGAGAAATA CAACGAAGCT CTGGAAGAAG ATGCTGCCAG AGCCTTTGCT
GAGGGTTGGC AGGCTCTCCC TCACTTTAGG AGGCCCTTTT TTGAGGAAGC TGCTGCAGAG
GTACCATCCC CTGATTCAGA GGTTTCCAGC TATTCCTCAA AATATGCCCC ACATTCATGG
CCTGAGTCAA GATTGGAGAG CAAGGCAAGG AAGCTGGTGC AGTTATTTCT GCTTATGGAT
TCAACTAAGC TGCCTATACC AAAGAAAGGA ATTCTGTACT ACATTGGCCG AGAGTGCAGC
AAAGTGTTCC CTGACCTCCT GAATCGTGCT GCCCGCACCC TGAACCATGT CTATGGGACA
GAACTAGTGG TACTTGATCC CAGGAATCAC TCCTATACTC TGTACAACCG AAGGGAGATG
GAAGAAACTG AGGAGATCGT AGACAGTCCA AACAGGCCTG GCAACAACTT TTTGATGCAG
GTCCTAAGCT TCATCTTTAT TATGGGCAAC CATGCCAGGG AGTCTGCAGT CTGGGCCTTT
CTGCGGGGCT TAGGGGTTCA AGCTGGGAGA AAGCATGTGA TTACCTGCAG ATACTTGAGT
CAGCGCTATA TAGACAGTTT ACGGGTTCCT GACAGTGATC CAGTGCAATA TGAGTTTGTA
TGGGGTCCTA GAGCCCGTTT GGAAACCTCT AAGATGAAAG CCTTGCGATA TGTGGCCAGA
ATCCACAGAA AGGAACCACA GGACTGGCCA CAGCAGTACA GGGAGGCAAT GGAAGATGAG
GCCAATAGAG CTGATGTTGG GCACAGGCAA ATCTTTGTTC ACAACTTCAG GTAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_065983.1
CDS279..3152
Misc Feature(1)174..176(+)
Misc Feature(2)741..>1169(+)
Misc Feature(3)1005..>1412(+)
Misc Feature(4)1770..2282(+)
Misc Feature(5)2505..3149(+)
Misc Feature(6)2532..3017(+)
Exon (1)1..3701
Gene:MAGEE1
Gene Synonym:
Translation
Position Chain Variation Link
275 275 a, g dbSNP:41307357
506 506 a, c dbSNP:7066146
768 768 c, g dbSNP:199741314
979 979 a, c dbSNP:200870196
1015 1015 a, c dbSNP:41298484
1293 1293 a, g dbSNP:200924313
1295 1295 c, g dbSNP:7051260
2305 2305 a, g dbSNP:201692321
3186 3186 c, g dbSNP:111339291
3349 3349 g, t dbSNP:28556695

Target ORF information:

RefSeq Version NM_020932
Organism Homo sapiens (human)
Definition Homo sapiens melanoma antigen family E1 (MAGEE1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_020932

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGTCTCTGG TAAGCCAGAA TTCGCGCCGC CGCCGCCGCC GCGTTGCAAA GGCTACTGCG 
CACAACAGCA GCTGGGGCGA AATGCAGGCC CCTAATGCCC CCGGTCTCCC CGCTGATGTG
CCAGGCTCAG ACGTCCCCCA GGGTCCCAGC GATTCCCAGA TCCTCCAGGG CCTCTGCGCC
TCTGAGGGCC CAAGCACCTC CGTTCTGCCC ACCTCCGCTG AGGGCCCAAG CACCTTTGTG
CCGCCCACCA TCTCTGAGGC CTCAAGCGCC TCCGGGCAGC CCACCATCTC TGAGGGACCT
GGCACCTCCG TGCTGCCCAC CCCCAGTGAG GGCCTAAGCA CCTCCGGGCC TCCCACCATC
TCTAAGGGGC TGTGCACCTC TGTGACGCTT GCCGCCTCTG AGGGCCGGAA CACCTCCAGG
CCGCCCACTT CCTCTGAGGA ACCTAGCACC TCCGTGCCGC CCACCGCCTC TGAGGTACCG
AGCACCTCCC TGCCGCCCAC CCCTGGTGAG GGAACGAGCA CCTCCGTGCC GCCCACAGCC
TATGAGGGAC CAAGCACCTC CGTGGTGCCC ACCCCTGATG AGGGACCAAG CACCTCCGTG
CTGCCTACAC CTGGTGAGGG ACCAGGCACC TCCGTGCCGC TCGCCGCCAC TGAGGGCCTG
AGCACCTCCG TGCAGGCCAC TCCTGATGAG GGACCGAGCA CCTCCGTGCC GCCCACCGCC
ACTGAGGGCC TAAGCACCCC CGTGCCACCC ACCCGTGATG AGGGACCGAG CACCTCCGTG
CCGGCCACTC CTGGTGAGGG ACCGAGCACC TCCGTGCTGC CCGCCGCCTC TGACGGACAA
AGCATCTCCT TGGTGCCCAC CCGCGGTAAG GGATCAAGCA CCTCCGTGCC CCCCACCGCC
ACCGAGGGCC TGAGCACCTC CGTGCAGCCC ACTGCTGGTG AGGGATCGAG CACCTCCGTG
CCGCCCACCC CTGGTGGGGG ACTGAGCACC TCCGTGCCGC CCACCGCCAC TGAGGAGTTG
AGCACCTCCG TGCCGCCCAC TCCCGGTGAG GGACCAAGCA CTTCCGTACT GCCAATCCCC
GGTGAGGGAC TGAGCACCTC TGTGCCGCCC ACCGCCTCTG ATGGATCGGA CACCTCCGTG
CCGCCCACTC CTGGTGAGGG CGCAAGCACC TTAGTGCAGC CCACCGCCCC TGACGGACCG
GGAAGCTCCG TGCTGCCTAA CCCTGGTGAG GGCCCGAGCA CATTGTTTAG CTCTAGTGCT
TCTGTGGACC GGAACCCCTC CAAGTGTTCC CTTGTTTTGC CAAGCCCTAG GGTAACCAAG
GCCTCCGTGG ACTCAGATTC TGAGGGTCCT AAGGGTGCAG AAGGCCCTAT AGAATTCGAG
GTCCTGAGAG ACTGTGAGAG CCCCAACTCC ATTAGTATTA TGGGCCTCAA TACTTCCCGG
GTTGCAATTA CCCTGAAGCC CCAAGACCCT ATGGAACAGA ACGTAGCTGA GCTGTTGCAG
TTCCTGCTGG TGAAGGATCA GAGCAAGTAC CCTATCCGGG AGTCTGAAAT GCGGGAATAT
ATTGTTAAAG AATATCGCAA CCAGTTTCCT GAGATACTCA GGCGAGCAGC AGCCCACCTG
GAGTGCATTT TTAGGTTTGA ATTGAGAGAA CTTGACCCTG AGGCACACAC CTACATTCTG
TTAAACAAAC TGGGACCTGT GCCCTTTGAA GGGTTAGAAG AGAGCCCAAA TGGGCCAAAG
ATGGGCCTCC TGATGATGAT TCTAGGCCAA ATATTCCTGA ATGGCAACCA AGCCAAGGAG
GCTGAGATTT GGGAAATGCT CTGGAGGATG GGGGTGCAGC GGGAAAGGAG GCTTTCCATT
TTTGGGAACC CAAAGAGACT TCTGTCTGTG GAGTTTGTAT GGCAGCGTTA CTTAGACTAC
AGGCCAGTAA CTGACTGTAA ACCAGTGGAG TATGAGTTTT TCTGGGGCCC AAGATCCCAC
CTAGAAACCA CCAAGATGAA AATTCTGAAG TTCATGGCGA AAATATATAA CAAAGATCCT
ATGGATTGGC CAGAGAAATA CAACGAAGCT CTGGAAGAAG ATGCTGCCAG AGCCTTTGCT
GAGGGTTGGC AGGCTCTCCC TCACTTTAGG AGGCCCTTTT TTGAGGAAGC TGCTGCAGAG
GTACCATCCC CTGATTCAGA GGTTTCCAGC TATTCCTCAA AATATGCCCC ACATTCATGG
CCTGAGTCAA GATTGGAGAG CAAGGCAAGG AAGCTGGTGC AGTTATTTCT GCTTATGGAT
TCAACTAAGC TGCCTATACC AAAGAAAGGA ATTCTGTACT ACATTGGCCG AGAGTGCAGC
AAAGTGTTCC CTGACCTCCT GAATCGTGCT GCCCGCACCC TGAACCATGT CTATGGGACA
GAACTAGTGG TACTTGATCC CAGGAATCAC TCCTATACTC TGTACAACCG AAGGGAGATG
GAAGAAACTG AGGAGATCGT AGACAGTCCA AACAGGCCTG GCAACAACTT TTTGATGCAG
GTCCTAAGCT TCATCTTTAT TATGGGCAAC CATGCCAGGG AGTCTGCAGT CTGGGCCTTT
CTGCGGGGCT TAGGGGTTCA AGCTGGGAGA AAGCATGTGA TTACCTGCAG ATACTTGAGT
CAGCGCTATA TAGACAGTTT ACGGGTTCCT GACAGTGATC CAGTGCAATA TGAGTTTGTA
TGGGGTCCTA GAGCCCGTTT GGAAACCTCT AAGATGAAAG CCTTGCGATA TGTGGCCAGA
ATCCACAGAA AGGAACCACA GGACTGGCCA CAGCAGTACA GGGAGGCAAT GGAAGATGAG
GCCAATAGAG CTGATGTTGG GCACAGGCAA ATCTTTGTTC ACAACTTCAG GTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.