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BCHE butyrylcholinesterase [Homo sapiens (human)]

Gene Symbol BCHE
Entrez Gene ID 590
Full Name butyrylcholinesterase
Synonyms CHE1, CHE2, E1
General protein information
Preferred Names
cholinesterase
Names
cholinesterase
cholinesterase 1
choline esterase II
pseudocholinesterase
butyrylcholine esterase
cholinesterase (serum) 2
acylcholine acylhydrolase
NP_000046.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

3

3q26.1-q26.2

Summary Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

177400

Disorder Html: Apnea, postanesthetic (3)
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OHu38088 XM_005247685 PREDICTED: Homo sapiens butyrylcholinesterase (BCHE), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK Not in stock 7-9 Starting from $99.00
OHu19300 NM_000055 Homo sapiens butyrylcholinesterase (BCHE), mRNA. pcDNA3.1-C-(k)DYK Not in stock 7-9 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OHu38088D
Sequence Information ORF Nucleotide Sequence (Length: 1932bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product cholinesterase isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_005612.17) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
ATGTCAGTGC AGTCCAATTT ACAGGCTGGA GCAGCAGCTG CATCCTGCAT TTCCCCGAAG 
TATTACATGA TTTTCACTCC TTGCAAACTT TGCCATCTTT GTTGCAGAGA ATCGGAAATC
AATATGCATA GCAAAGTCAC AATCATATGC ATCAGATTTC TCTTTTGGTT TCTTTTGCTC
TGCATGCTTA TTGGGAAGTC ACATACTGAA GATGACATCA TAATTGCAAC AAAGAATGGA
AAAGTCAGAG GGATGAACTT GACAGTTTTT GGTGGCACGG TAACAGCCTT TCTTGGAATT
CCCTATGCAC AGCCACCTCT TGGTAGACTT CGATTCAAAA AGCCACAGTC TCTGACCAAG
TGGTCTGATA TTTGGAATGC CACAAAATAT GCAAATTCTT GCTGTCAGAA CATAGATCAA
AGTTTTCCAG GCTTCCATGG ATCAGAGATG TGGAACCCAA ACACTGACCT CAGTGAAGAC
TGTTTATATC TAAATGTATG GATTCCAGCA CCTAAACCAA AAAATGCCAC TGTATTGATA
TGGATTTATG GTGGTGGTTT TCAAACTGGA ACATCATCTT TACATGTTTA TGATGGCAAG
TTTCTGGCTC GGGTTGAAAG AGTTATTGTA GTGTCAATGA ACTATAGGGT GGGTGCCCTA
GGATTCTTAG CTTTGCCAGG AAATCCTGAG GCTCCAGGGA ACATGGGTTT ATTTGATCAA
CAGTTGGCTC TTCAGTGGGT TCAAAAAAAT ATAGCAGCCT TTGGTGGAAA TCCTAAAAGT
GTAACTCTCT TTGGAGAAAG TGCAGGAGCA GCTTCAGTTA GCCTGCATTT GCTTTCTCCT
GGAAGCCATT CATTGTTCAC CAGAGCCATT CTGCAAAGTG GATCCTTTAA TGCTCCTTGG
GCGGTAACAT CTCTTTATGA AGCTAGGAAC AGAACGTTGA ACTTAGCTAA ATTGACTGGT
TGCTCTAGAG AGAATGAGAC TGAAATAATC AAGTGTCTTA GAAATAAAGA TCCCCAAGAA
ATTCTTCTGA ATGAAGCATT TGTTGTCCCC TATGGGACTC CTTTGTCAGT AAACTTTGGT
CCGACCGTGG ATGGTGATTT TCTCACTGAC ATGCCAGACA TATTACTTGA ACTTGGACAA
TTTAAAAAAA CCCAGATTTT GGTGGGTGTT AATAAAGATG AAGGGACAGC TTTTTTAGTC
TATGGTGCTC CTGGCTTCAG CAAAGATAAC AATAGTATCA TAACTAGAAA AGAATTTCAG
GAAGGTTTAA AAATATTTTT TCCAGGAGTG AGTGAGTTTG GAAAGGAATC CATCCTTTTT
CATTACACAG ACTGGGTAGA TGATCAGAGA CCTGAAAACT ACCGTGAGGC CTTGGGTGAT
GTTGTTGGGG ATTATAATTT CATATGCCCT GCCTTGGAGT TCACCAAGAA GTTCTCAGAA
TGGGGAAATA ATGCCTTTTT CTACTATTTT GAACACCGAT CCTCCAAACT TCCGTGGCCA
GAATGGATGG GAGTGATGCA TGGCTATGAA ATTGAATTTG TCTTTGGTTT ACCTCTGGAA
AGAAGAGATA ATTACACAAA AGCCGAGGAA ATTTTGAGTA GATCCATAGT GAAACGGTGG
GCAAATTTTG CAAAATATGG GAATCCAAAT GAGACTCAGA ACAATAGCAC AAGCTGGCCT
GTCTTCAAAA GCACTGAACA AAAATATCTA ACCTTGAATA CAGAGTCAAC AAGAATAATG
ACGAAACTAC GTGCTCAACA ATGTCGATTC TGGACATCAT TTTTTCCAAA AGTCTTGGAA
ATGACAGGAA ATATTGATGA AGCAGAATGG GAGTGGAAAG CAGGATTCCA TCGCTGGAAC
AATTACATGA TGGACTGGAA AAATCAATTT AACGATTACA CTAGCAAGAA AGAAAGTTGT
GTGGGTCTCTT AA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqXP_005247742.1
CDS45..1976
Misc Feature(1)264..1787(+)
Misc Feature(2)540..>917(+)
Misc Feature(3)594..1577(+)
Misc Feature(4)843..1565(+)
Misc Feature(5)1860..1973(+)
Translation
Position Chain Variation Link
10 10 a, c dbSNP:765253646
11 11 a, g dbSNP:761912325
12 12 a, g dbSNP:530515511
36 36 g, t dbSNP:562054493
37 37 a, g dbSNP:547400578
48 48 a, t dbSNP:769880025
64 64 c, t dbSNP:541713553
71 71 c, t dbSNP:776506432
111 111 a, g dbSNP:768588350
113 113 -, g dbSNP:779676057
128 128 a, c dbSNP:746031095
136 136 a, g dbSNP:1126680
167 167 g, t dbSNP:529294559
168 168 a, g dbSNP:755391002
169 169 c, t dbSNP:751910853
176 176 a, c dbSNP:149985624
181 181 c, t dbSNP:758046853
183 183 a, t dbSNP:55950599
186 186 a, g dbSNP:764846974
188 188 a, c dbSNP:374939607
191 191 a, g dbSNP:776735567
192 192 g, t dbSNP:763759719
204 204 a, c dbSNP:372942772
213 213 c, t dbSNP:760484389
220 220 g, t dbSNP:775196097
232 232 g, t dbSNP:771168157
234 234 a, g dbSNP:114063013
238 238 a, g dbSNP:773207113
246 246 c, t dbSNP:769875412
265 265 c, t dbSNP:748604050
267 267 -, a dbSNP:750309713
280 280 a, g dbSNP:781642185
281 281 c, t dbSNP:769092899
286 286 a, g dbSNP:116047990
296 296 c, g dbSNP:201226143
303 303 a, t dbSNP:568396107
307 307 -, ca dbSNP:765565615
316 316 -, g dbSNP:762189020
319 319 -, g dbSNP:767311284
322 322 a, c, t dbSNP:56309853
323 323 a, g dbSNP:150673481
324 324 g, t dbSNP:756863360
326 326 a, g dbSNP:368402967
328 328 c, t dbSNP:377250579
331 331 a, c, g dbSNP:114355070
333 333 a, t dbSNP:531738678
342 342 a, g dbSNP:767219925
343 343 c, t dbSNP:763101056
349 349 a, g dbSNP:116097205
350 350 c, t dbSNP:769824118
360 360 c, t dbSNP:148170012
363 363 c, g dbSNP:776750503
367 367 a, g dbSNP:769202966
373 373 g, t dbSNP:777330640
375 375 a, c, t dbSNP:780411054
376 376 a, g, t dbSNP:745482371
378 378 a, t dbSNP:367844208
380 380 a, c dbSNP:757016659
397 397 c, t dbSNP:753381521
413 413 c, t dbSNP:374649054
460 460 a, g dbSNP:1799807
465 465 a, t dbSNP:370612464
481 481 a, g dbSNP:200035175
482 482 c, t dbSNP:759357575
489 489 c, g dbSNP:751406038
492 492 a, c dbSNP:765432162
493 493 c, t dbSNP:762091295
494 494 a, g dbSNP:149045543
495 495 c, t dbSNP:764097445
499 499 a, g dbSNP:534940179
501 501 c, g dbSNP:761197925
506 506 -, c dbSNP:754304373
510 510 g, t dbSNP:775897605
513 513 c, t dbSNP:374198965
519 519 a, g dbSNP:746209182
522 522 g, t dbSNP:137883811
529 529 g, t dbSNP:531492019
538 538 a, c dbSNP:748950254
544 544 a, g dbSNP:777278160
548 548 g, t dbSNP:755600722
549 549 c, t dbSNP:3732880
556 556 c, g dbSNP:553041362
568 568 -, a dbSNP:764588882
570 570 a, g dbSNP:780960236
573 573 a, c dbSNP:754968149
582 582 a, t dbSNP:751352739
585 585 c, t dbSNP:766168551
590 590 c, t dbSNP:757414059
595 595 a, g dbSNP:201820739
601 601 -, a dbSNP:55703238
602 602 -, g dbSNP:774072493
602 602 a, g, t dbSNP:71534242
602 602 ag, t dbSNP:398124632
605 605 a, c, t dbSNP:775692720
606 606 c, g, t dbSNP:760182781
612 612 a, g dbSNP:774787910
614 614 a, g dbSNP:114203545
617 617 a, t dbSNP:748920052
620 620 a, g dbSNP:772770904
626 626 a, g, t dbSNP:747598704
630 630 a, g dbSNP:780821820
632 632 c, t dbSNP:200478369
634 634 a, g, t dbSNP:121918558
640 640 g, t dbSNP:747692777
650 650 a, c, g dbSNP:779779259
651 651 a, g dbSNP:755323641
655 655 a, g dbSNP:141243848
657 657 a, g dbSNP:758223727
662 662 -, aaga dbSNP:772259613
663 663 -, a dbSNP:775417513
664 664 g, t dbSNP:750277149
675 675 a, c, g dbSNP:527843566
676 676 c, t dbSNP:576781299
684 684 a, g dbSNP:767707514
686 686 c, g dbSNP:760761804
688 688 a, g dbSNP:147790353
689 689 c, t dbSNP:752133294
698 698 c, t dbSNP:766808993
699 699 a, g dbSNP:149719695
702 702 c, t dbSNP:140807357
710 710 c, t dbSNP:769327758
727 727 a, t dbSNP:761532924
728 728 a, t dbSNP:151020233
737 737 c, t dbSNP:115463466
740 740 a, g dbSNP:139541965
743 743 g, t dbSNP:537314243
746 746 c, t dbSNP:746911409
747 747 a, g dbSNP:779938781
748 748 c, t dbSNP:772099944
751 751 a, g dbSNP:745641055
754 754 c, t dbSNP:778831301
759 759 a, g dbSNP:756220623
760 760 a, t dbSNP:752974306
761 761 g, t dbSNP:781368801
765 765 c, t dbSNP:376351866
768 768 a, c, t dbSNP:766971452
780 780 c, t dbSNP:763584348
780 780 -, t dbSNP:774761275
782 782 g, t dbSNP:568724445
783 783 a, c, g dbSNP:761325231
787 787 a, g dbSNP:776298663
793 793 -, a dbSNP:769660002
799 799 c, g dbSNP:768341160
802 802 c, t dbSNP:114706984
805 805 c, t dbSNP:775043863
807 807 a, g dbSNP:771895178
810 810 a, g dbSNP:373564630
820 820 a, g dbSNP:143560894
832 832 c, t dbSNP:764841347
833 833 -, cttt dbSNP:781221905
833 833 -, ct dbSNP:747983616
843 843 a, g dbSNP:370077923
850 850 a, g dbSNP:775478077
855 855 g, t dbSNP:781532109
857 857 c, t dbSNP:114127364
860 860 a, c dbSNP:751675958
861 861 g, t dbSNP:780186341
866 866 c, g dbSNP:769497610
884 884 c, t dbSNP:187613357
886 886 -, tcccc dbSNP:768705190
887 887 -, g dbSNP:747037935
890 890 a, c dbSNP:750964403
893 893 -, gtgatc dbSNP:757977872
895 895 c, t dbSNP:765480578
898 898 c, t dbSNP:757612378
907 907 c, g dbSNP:754253344
908 908 a, g dbSNP:763725995
924 924 g, t dbSNP:140080572
925 925 c, g dbSNP:774909282
930 930 c, t dbSNP:767064134
933 933 a, c dbSNP:759339103
940 940 c, t dbSNP:774374578
945 945 a, g dbSNP:770811946
946 946 c, t dbSNP:749068794
947 947 a, g dbSNP:773199170
951 951 -, a dbSNP:749996456
952 952 c, t dbSNP:759334506
953 953 a, g dbSNP:768933717
954 954 a, t dbSNP:747249411
960 960 -, t dbSNP:778568717
961 961 a, g dbSNP:776427090
966 966 g, t dbSNP:779950479
971 971 a, g dbSNP:758538643
979 979 c, t dbSNP:28933389
992 992 g, t dbSNP:779456773
996 996 c, t dbSNP:757823110
999 999 -, actg dbSNP:757549524
1011 1011 a, g dbSNP:746642541
1015 1015 a, g dbSNP:375775245
1016 1016 c, g dbSNP:16849700
1029 1029 a, g dbSNP:755701726
1030 1030 c, t dbSNP:752365776
1031 1031 a, c dbSNP:766894981
1037 1037 c, g dbSNP:759053642
1038 1038 a, t dbSNP:564041751
1045 1045 a, g dbSNP:766326312
1047 1047 a, t dbSNP:550866478
1051 1051 a, g dbSNP:115624085
1061 1061 a, g dbSNP:138271111
1062 1062 g, t dbSNP:747196387
1072 1072 c, t dbSNP:372593716
1093 1093 c, t dbSNP:775752216
1096 1096 a, g dbSNP:772234528
1101 1101 a, t dbSNP:114991020
1104 1104 c, t dbSNP:572660949
1105 1105 c, t dbSNP:771576791
1108 1108 g, t dbSNP:142586213
1125 1125 c, g dbSNP:749805953
1126 1126 c, t dbSNP:116607681
1127 1127 a, g dbSNP:368885671
1130 1130 c, g, t dbSNP:780873168
1131 1131 a, g dbSNP:754644618
1137 1137 a, g dbSNP:751075598
1154 1154 c, t dbSNP:766000843
1157 1157 a, g dbSNP:762936157
1159 1159 a, c dbSNP:150912772
1164 1164 a, g dbSNP:765307050
1171 1171 c, t dbSNP:104893684
1180 1180 a, g dbSNP:776350992
1187 1187 a, t dbSNP:557112656
1188 1188 a, t dbSNP:772337347
1189 1189 a, g dbSNP:759686297
1194 1194 -, acccagatt dbSNP:764498866
1194 1194 -, a dbSNP:754214624
1194 1194 a, t dbSNP:537434945
1205 1205 g, t dbSNP:771017682
1206 1206 a, g dbSNP:749752833
1220 1220 a, g dbSNP:778225256
1227 1227 a, g dbSNP:753657650
1234 1234 a, c dbSNP:770337031
1235 1235 a, t dbSNP:748533851
1236 1236 g, t dbSNP:781476667
1238 1238 c, t dbSNP:376091945
1239 1239 a, t dbSNP:121918557
1244 1244 c, t dbSNP:143300460
1245 1245 g, t dbSNP:201120931
1254 1254 c, t dbSNP:757948667
1257 1257 g, t dbSNP:750000733
1258 1258 c, g dbSNP:765249814
1262 1262 c, g dbSNP:139312740
1269 1269 -, g dbSNP:761080105
1270 1270 a, t dbSNP:753598758
1274 1274 -, caa dbSNP:753284945
1276 1276 a, g dbSNP:763806377
1296 1296 a, g dbSNP:534912670
1301 1301 c, t dbSNP:774590309
1304 1304 a, g dbSNP:372839550
1308 1308 a, g dbSNP:763000328
1309 1309 c, g, t dbSNP:373114728
1313 1313 a, c dbSNP:748608343
1317 1317 a, g dbSNP:146936556
1325 1325 -, t dbSNP:767469658
1338 1338 -, gagt dbSNP:759679732
1344 1344 c, g dbSNP:115129687
1345 1345 a, g dbSNP:747438953
1359 1359 c, t dbSNP:779828972
1362 1362 c, t dbSNP:760610944
1364 1364 -, t dbSNP:35979453
1365 1365 c, t dbSNP:758179631
1380 1380 c, g dbSNP:775490283
1384 1384 -, a dbSNP:768148788
1407 1407 c, t dbSNP:745364489
1408 1408 a, g dbSNP:778566503
1409 1409 c, t dbSNP:142671799
1413 1413 a, g dbSNP:753746052
1414 1414 c, t dbSNP:763914169
1420 1420 a, c, g, t dbSNP:28933390
1426 1426 c, t dbSNP:369207253
1434 1434 g, t dbSNP:773210938
1450 1450 a, g dbSNP:149097236
1451 1451 c, g dbSNP:762341786
1455 1455 g, t dbSNP:776972298
1456 1456 a, c dbSNP:562543522
1463 1463 a, g dbSNP:755959806
1469 1469 a, c, g dbSNP:780384860
1482 1482 a, c, g dbSNP:771781499
1486 1486 c, g dbSNP:539504704
1489 1489 a, g dbSNP:778513166
1491 1491 a, t dbSNP:369840366
1494 1494 a, c dbSNP:144987429
1496 1496 a, t dbSNP:570544890
1497 1497 a, g dbSNP:201490686
1499 1499 a, c dbSNP:756136656
1500 1500 a, t dbSNP:752486524
1510 1510 a, c dbSNP:767306248
1518 1518 c, g dbSNP:373022811
1520 1520 c, t dbSNP:267599673
1521 1521 c, t dbSNP:530517316
1530 1530 a, g dbSNP:765535291
1537 1537 c, g dbSNP:761774959
1538 1538 a, g dbSNP:369712135
1542 1542 a, c dbSNP:776827931
1554 1554 -, ctat dbSNP:763329644
1557 1557 a, g dbSNP:764502386
1558 1558 -, tg dbSNP:776566122
1558 1558 g, t dbSNP:761266167
1561 1561 -, a dbSNP:768538614
1564 1564 a, g dbSNP:775935293
1566 1566 a, g dbSNP:772583466
1567 1567 a, g dbSNP:745482363
1580 1580 a, g dbSNP:370506433
1586 1586 c, g dbSNP:377230118
1591 1591 g, t dbSNP:770669263
1592 1592 c, t dbSNP:372860529
1597 1597 c, t dbSNP:200151790
1598 1598 a, t dbSNP:769553145
1600 1600 c, t dbSNP:748092565
1605 1605 a, g dbSNP:150384913
1613 1613 a, t dbSNP:754736317
1617 1617 c, t dbSNP:751404124
1628 1628 c, t dbSNP:74458984
1629 1629 a, g dbSNP:200998515
1633 1633 a, g dbSNP:753791456
1649 1649 c, t dbSNP:764244573
1652 1652 a, g, t dbSNP:753283945
1656 1656 a, t dbSNP:768182433
1658 1658 a, t dbSNP:759961675
1659 1659 c, t dbSNP:115017300
1660 1660 a, g dbSNP:559088873
1666 1666 c, t dbSNP:762673285
1668 1668 a, c dbSNP:772540228
1671 1671 c, t dbSNP:769316835
1682 1682 c, t dbSNP:545580167
1684 1684 c, g, t dbSNP:532499978
1685 1685 g, t dbSNP:755486397
1692 1692 a, g dbSNP:752132070
1699 1699 c, g dbSNP:200768861
1711 1711 c, g dbSNP:371869257
1717 1717 a, g dbSNP:367912630
1719 1719 c, t dbSNP:755648929
1720 1720 a, g dbSNP:764864897
1722 1722 c, g dbSNP:761458446
1727 1727 c, t dbSNP:533603961
1741 1741 a, t dbSNP:121918556
1751 1751 a, t dbSNP:760485585
1756 1756 a, c dbSNP:371901966
1762 1762 a, g dbSNP:771956376
1780 1780 c, t dbSNP:77586249
1786 1786 c, t dbSNP:200817146
1787 1787 a, g dbSNP:774356916
1794 1794 c, t dbSNP:199660374
1795 1795 a, g dbSNP:374499560
1797 1797 c, g dbSNP:781374688
1806 1806 c, t dbSNP:755117040
1809 1809 c, t dbSNP:747099939
1810 1810 g, t dbSNP:780597019
1819 1819 c, t dbSNP:545173403
1820 1820 a, g dbSNP:750718617
1822 1822 c, t dbSNP:116333990
1824 1824 c, t dbSNP:756850483
1825 1825 a, t dbSNP:753517208
1829 1829 c, t dbSNP:116021719
1831 1831 a, c dbSNP:199551421
1835 1835 a, c dbSNP:763772612
1858 1858 c, t dbSNP:114166903
1862 1862 a, c, t dbSNP:778008893
1866 1866 a, g dbSNP:1803274
1867 1867 c, t dbSNP:752317854
1879 1879 a, g dbSNP:780715428
1882 1882 a, g dbSNP:151075873
1896 1896 c, t dbSNP:751164424
1897 1897 a, g, t dbSNP:762988755
1903 1903 a, g dbSNP:750175032
1904 1904 a, c dbSNP:764962053
1913 1913 c, g dbSNP:760910642
1923 1923 a, g dbSNP:775541959
1928 1928 c, t dbSNP:767826363
1934 1934 c, t dbSNP:759594959
1935 1935 a, g dbSNP:774484015
1936 1936 a, g dbSNP:199590217
1937 1937 c, t dbSNP:771363401
1938 1938 a, g dbSNP:749814210
1943 1943 -, cacta dbSNP:745387582
1948 1948 g, t dbSNP:142859898
1961 1961 c, t dbSNP:148569288
1965 1965 a, g, t dbSNP:373551373
1968 1968 g, t dbSNP:748586820
1969 1969 -, g dbSNP:535319263
1969 1969 g, t dbSNP:780688435
1983 1983 a, g dbSNP:754737274
1989 1989 c, t dbSNP:56084310
2002 2002 a, c dbSNP:779722552
2010 2010 c, t dbSNP:758361514
2012 2012 -, ttagatcaaggcaaaaat dbSNP:201751925
2013 2013 c, t dbSNP:750357744
2023 2023 a, c dbSNP:537887596
2032 2032 c, g dbSNP:191995340
2080 2080 c, g dbSNP:759407697
2108 2108 c, t dbSNP:556141230
2115 2115 a, t dbSNP:145327297
2138 2138 a, g dbSNP:567077263
2156 2156 a, g dbSNP:139885577
2165 2165 a, g dbSNP:3495
2166 2166 c, t dbSNP:55765003
2177 2177 a, g dbSNP:55781241
2182 2182 a, c dbSNP:1042406
2186 2186 c, t dbSNP:571279565
2225 2225 a, t dbSNP:150581482
2257 2257 a, c dbSNP:55753636
2261 2261 c, t dbSNP:55729116
2264 2264 -, t dbSNP:397762799
2264 2264 g, t dbSNP:371032418
2266 2266 -, g dbSNP:746868218
2269 2269 -, t, tt dbSNP:3836432
2270 2270 c, t dbSNP:199567692
2273 2273 c, t dbSNP:568512358
2291 2291 c, t dbSNP:369786680
2296 2296 c, t dbSNP:548870275
2304 2304 c, t dbSNP:529114188
2323 2323 a, c, t dbSNP:760760763
2325 2325 a, g dbSNP:55849903
2424 2424 c, t dbSNP:148490591
2431 2431 c, t dbSNP:187886111
2440 2440 a, t dbSNP:757059420
2443 2443 c, g dbSNP:144542474

Target ORF information:

RefSeq Version XM_005247685
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens butyrylcholinesterase (BCHE), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
XM_005247685

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
ATGTCAGTGC AGTCCAATTT ACAGGCTGGA GCAGCAGCTG CATCCTGCAT TTCCCCGAAG 
TATTACATGA TTTTCACTCC TTGCAAACTT TGCCATCTTT GTTGCAGAGA ATCGGAAATC
AATATGCATA GCAAAGTCAC AATCATATGC ATCAGATTTC TCTTTTGGTT TCTTTTGCTC
TGCATGCTTA TTGGGAAGTC ACATACTGAA GATGACATCA TAATTGCAAC AAAGAATGGA
AAAGTCAGAG GGATGAACTT GACAGTTTTT GGTGGCACGG TAACAGCCTT TCTTGGAATT
CCCTATGCAC AGCCACCTCT TGGTAGACTT CGATTCAAAA AGCCACAGTC TCTGACCAAG
TGGTCTGATA TTTGGAATGC CACAAAATAT GCAAATTCTT GCTGTCAGAA CATAGATCAA
AGTTTTCCAG GCTTCCATGG ATCAGAGATG TGGAACCCAA ACACTGACCT CAGTGAAGAC
TGTTTATATC TAAATGTATG GATTCCAGCA CCTAAACCAA AAAATGCCAC TGTATTGATA
TGGATTTATG GTGGTGGTTT TCAAACTGGA ACATCATCTT TACATGTTTA TGATGGCAAG
TTTCTGGCTC GGGTTGAAAG AGTTATTGTA GTGTCAATGA ACTATAGGGT GGGTGCCCTA
GGATTCTTAG CTTTGCCAGG AAATCCTGAG GCTCCAGGGA ACATGGGTTT ATTTGATCAA
CAGTTGGCTC TTCAGTGGGT TCAAAAAAAT ATAGCAGCCT TTGGTGGAAA TCCTAAAAGT
GTAACTCTCT TTGGAGAAAG TGCAGGAGCA GCTTCAGTTA GCCTGCATTT GCTTTCTCCT
GGAAGCCATT CATTGTTCAC CAGAGCCATT CTGCAAAGTG GATCCTTTAA TGCTCCTTGG
GCGGTAACAT CTCTTTATGA AGCTAGGAAC AGAACGTTGA ACTTAGCTAA ATTGACTGGT
TGCTCTAGAG AGAATGAGAC TGAAATAATC AAGTGTCTTA GAAATAAAGA TCCCCAAGAA
ATTCTTCTGA ATGAAGCATT TGTTGTCCCC TATGGGACTC CTTTGTCAGT AAACTTTGGT
CCGACCGTGG ATGGTGATTT TCTCACTGAC ATGCCAGACA TATTACTTGA ACTTGGACAA
TTTAAAAAAA CCCAGATTTT GGTGGGTGTT AATAAAGATG AAGGGACAGC TTTTTTAGTC
TATGGTGCTC CTGGCTTCAG CAAAGATAAC AATAGTATCA TAACTAGAAA AGAATTTCAG
GAAGGTTTAA AAATATTTTT TCCAGGAGTG AGTGAGTTTG GAAAGGAATC CATCCTTTTT
CATTACACAG ACTGGGTAGA TGATCAGAGA CCTGAAAACT ACCGTGAGGC CTTGGGTGAT
GTTGTTGGGG ATTATAATTT CATATGCCCT GCCTTGGAGT TCACCAAGAA GTTCTCAGAA
TGGGGAAATA ATGCCTTTTT CTACTATTTT GAACACCGAT CCTCCAAACT TCCGTGGCCA
GAATGGATGG GAGTGATGCA TGGCTATGAA ATTGAATTTG TCTTTGGTTT ACCTCTGGAA
AGAAGAGATA ATTACACAAA AGCCGAGGAA ATTTTGAGTA GATCCATAGT GAAACGGTGG
GCAAATTTTG CAAAATATGG GAATCCAAAT GAGACTCAGA ACAATAGCAC AAGCTGGCCT
GTCTTCAAAA GCACTGAACA AAAATATCTA ACCTTGAATA CAGAGTCAAC AAGAATAATG
ACGAAACTAC GTGCTCAACA ATGTCGATTC TGGACATCAT TTTTTCCAAA AGTCTTGGAA
ATGACAGGAA ATATTGATGA AGCAGAATGG GAGTGGAAAG CAGGATTCCA TCGCTGGAAC
AATTACATGA TGGACTGGAA AAATCAATTT AACGATTACA CTAGCAAGAA AGAAAGTTGT
GTGGGTCTCTT AA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.


CloneID OHu19300D
Sequence Information ORF Nucleotide Sequence (Length: 1809bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product cholinesterase precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA426203.1, BC018141.1 and BF056152.1. This sequence is a reference standard in the RefSeqGene project. On May 23, 2007 this sequence version replaced gi:4557350. Summary: Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:3542989) ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: M16474.1, M16541.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
ATGCATAGCA AAGTCACAAT CATATGCATC AGATTTCTCT TTTGGTTTCT TTTGCTCTGC 
ATGCTTATTG GGAAGTCACA TACTGAAGAT GACATCATAA TTGCAACAAA GAATGGAAAA
GTCAGAGGGA TGAACTTGAC AGTTTTTGGT GGCACGGTAA CAGCCTTTCT TGGAATTCCC
TATGCACAGC CACCTCTTGG TAGACTTCGA TTCAAAAAGC CACAGTCTCT GACCAAGTGG
TCTGATATTT GGAATGCCAC AAAATATGCA AATTCTTGCT GTCAGAACAT AGATCAAAGT
TTTCCAGGCT TCCATGGATC AGAGATGTGG AACCCAAACA CTGACCTCAG TGAAGACTGT
TTATATCTAA ATGTATGGAT TCCAGCACCT AAACCAAAAA ATGCCACTGT ATTGATATGG
ATTTATGGTG GTGGTTTTCA AACTGGAACA TCATCTTTAC ATGTTTATGA TGGCAAGTTT
CTGGCTCGGG TTGAAAGAGT TATTGTAGTG TCAATGAACT ATAGGGTGGG TGCCCTAGGA
TTCTTAGCTT TGCCAGGAAA TCCTGAGGCT CCAGGGAACA TGGGTTTATT TGATCAACAG
TTGGCTCTTC AGTGGGTTCA AAAAAATATA GCAGCCTTTG GTGGAAATCC TAAAAGTGTA
ACTCTCTTTG GAGAAAGTGC AGGAGCAGCT TCAGTTAGCC TGCATTTGCT TTCTCCTGGA
AGCCATTCAT TGTTCACCAG AGCCATTCTG CAAAGTGGAT CCTTTAATGC TCCTTGGGCG
GTAACATCTC TTTATGAAGC TAGGAACAGA ACGTTGAACT TAGCTAAATT GACTGGTTGC
TCTAGAGAGA ATGAGACTGA AATAATCAAG TGTCTTAGAA ATAAAGATCC CCAAGAAATT
CTTCTGAATG AAGCATTTGT TGTCCCCTAT GGGACTCCTT TGTCAGTAAA CTTTGGTCCG
ACCGTGGATG GTGATTTTCT CACTGACATG CCAGACATAT TACTTGAACT TGGACAATTT
AAAAAAACCC AGATTTTGGT GGGTGTTAAT AAAGATGAAG GGACAGCTTT TTTAGTCTAT
GGTGCTCCTG GCTTCAGCAA AGATAACAAT AGTATCATAA CTAGAAAAGA ATTTCAGGAA
GGTTTAAAAA TATTTTTTCC AGGAGTGAGT GAGTTTGGAA AGGAATCCAT CCTTTTTCAT
TACACAGACT GGGTAGATGA TCAGAGACCT GAAAACTACC GTGAGGCCTT GGGTGATGTT
GTTGGGGATT ATAATTTCAT ATGCCCTGCC TTGGAGTTCA CCAAGAAGTT CTCAGAATGG
GGAAATAATG CCTTTTTCTA CTATTTTGAA CACCGATCCT CCAAACTTCC GTGGCCAGAA
TGGATGGGAG TGATGCATGG CTATGAAATT GAATTTGTCT TTGGTTTACC TCTGGAAAGA
AGAGATAATT ACACAAAAGC CGAGGAAATT TTGAGTAGAT CCATAGTGAA ACGGTGGGCA
AATTTTGCAA AATATGGGAA TCCAAATGAG ACTCAGAACA ATAGCACAAG CTGGCCTGTC
TTCAAAAGCA CTGAACAAAA ATATCTAACC TTGAATACAG AGTCAACAAG AATAATGACG
AAACTACGTG CTCAACAATG TCGATTCTGG ACATCATTTT TTCCAAAAGT CTTGGAAATG
ACAGGAAATA TTGATGAAGC AGAATGGGAG TGGAAAGCAG GATTCCATCG CTGGAACAAT
TACATGATGG ACTGGAAAAA TCAATTTAAC GATTACACTA GCAAGAAAGA AAGTTGTGTG
GGTCTCTAA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_000046.1
CDS161..1969
Misc Feature(1)35..37(+)
Misc Feature(2)257..1780(+)
Misc Feature(3)293..295(+)
Misc Feature(4)413..415(+)
Misc Feature(5)533..>910(+)
Misc Feature(6)560..562(+)
Misc Feature(7)587..1570(+)
Misc Feature(8)590..595(+)
Misc Feature(9)836..1558(+)
Misc Feature(10)836..838(+)
Misc Feature(11)965..967(+)
Misc Feature(12)1010..1012(+)
Misc Feature(13)1265..1267(+)
Misc Feature(14)1607..1609(+)
Misc Feature(15)1685..1687(+)
Misc Feature(16)1700..1702(+)
Misc Feature(17)1853..1966(+)
Exon (1)1..152
Gene:BCHE
Gene Synonym:
Exon (2)153..1677
Gene:BCHE
Gene Synonym:
Exon (3)1678..1844
Gene:BCHE
Gene Synonym:
Exon (4)1845..2447
Gene:BCHE
Gene Synonym:
Translation
Position Chain Variation Link
3 3 a, c dbSNP:765253646
4 4 a, g dbSNP:761912325
5 5 a, g dbSNP:530515511
29 29 g, t dbSNP:562054493
30 30 a, g dbSNP:547400578
41 41 a, t dbSNP:769880025
57 57 c, t dbSNP:541713553
64 64 c, t dbSNP:776506432
104 104 a, g dbSNP:768588350
106 106 -, g dbSNP:779676057
121 121 a, c dbSNP:746031095
129 129 a, g dbSNP:1126680
160 160 g, t dbSNP:529294559
161 161 a, g dbSNP:755391002
162 162 c, t dbSNP:751910853
169 169 a, c dbSNP:149985624
174 174 c, t dbSNP:758046853
176 176 a, t dbSNP:55950599
179 179 a, g dbSNP:764846974
181 181 a, c dbSNP:374939607
184 184 a, g dbSNP:776735567
185 185 g, t dbSNP:763759719
197 197 a, c dbSNP:372942772
206 206 c, t dbSNP:760484389
213 213 g, t dbSNP:775196097
225 225 g, t dbSNP:771168157
227 227 a, g dbSNP:114063013
231 231 a, g dbSNP:773207113
239 239 c, t dbSNP:769875412
258 258 c, t dbSNP:748604050
260 260 -, a dbSNP:750309713
273 273 a, g dbSNP:781642185
274 274 c, t dbSNP:769092899
279 279 a, g dbSNP:116047990
289 289 c, g dbSNP:201226143
296 296 a, t dbSNP:568396107
300 300 -, ca dbSNP:765565615
309 309 -, g dbSNP:762189020
312 312 -, g dbSNP:767311284
315 315 a, c, t dbSNP:56309853
316 316 a, g dbSNP:150673481
317 317 g, t dbSNP:756863360
319 319 a, g dbSNP:368402967
321 321 c, t dbSNP:377250579
324 324 a, c, g dbSNP:114355070
326 326 a, t dbSNP:531738678
335 335 a, g dbSNP:767219925
336 336 c, t dbSNP:763101056
342 342 a, g dbSNP:116097205
343 343 c, t dbSNP:769824118
353 353 c, t dbSNP:148170012
356 356 c, g dbSNP:776750503
360 360 a, g dbSNP:769202966
366 366 g, t dbSNP:777330640
368 368 a, c, t dbSNP:780411054
369 369 a, g, t dbSNP:745482371
371 371 a, t dbSNP:367844208
373 373 a, c dbSNP:757016659
390 390 c, t dbSNP:753381521
406 406 c, t dbSNP:374649054
453 453 a, g dbSNP:1799807
458 458 a, t dbSNP:370612464
474 474 a, g dbSNP:200035175
475 475 c, t dbSNP:759357575
482 482 c, g dbSNP:751406038
485 485 a, c dbSNP:765432162
486 486 c, t dbSNP:762091295
487 487 a, g dbSNP:149045543
488 488 c, t dbSNP:764097445
492 492 a, g dbSNP:534940179
494 494 c, g dbSNP:761197925
499 499 -, c dbSNP:754304373
503 503 g, t dbSNP:775897605
506 506 c, t dbSNP:374198965
512 512 a, g dbSNP:746209182
515 515 g, t dbSNP:137883811
522 522 g, t dbSNP:531492019
531 531 a, c dbSNP:748950254
537 537 a, g dbSNP:777278160
541 541 g, t dbSNP:755600722
542 542 c, t dbSNP:3732880
549 549 c, g dbSNP:553041362
561 561 -, a dbSNP:764588882
563 563 a, g dbSNP:780960236
566 566 a, c dbSNP:754968149
575 575 a, t dbSNP:751352739
578 578 c, t dbSNP:766168551
583 583 c, t dbSNP:757414059
588 588 a, g dbSNP:201820739
594 594 -, a dbSNP:55703238
595 595 -, g dbSNP:774072493
595 595 a, g, t dbSNP:71534242
595 595 ag, t dbSNP:398124632
598 598 a, c, t dbSNP:775692720
599 599 c, g, t dbSNP:760182781
605 605 a, g dbSNP:774787910
607 607 a, g dbSNP:114203545
610 610 a, t dbSNP:748920052
613 613 a, g dbSNP:772770904
619 619 a, g, t dbSNP:747598704
623 623 a, g dbSNP:780821820
625 625 c, t dbSNP:200478369
627 627 a, g, t dbSNP:121918558
633 633 g, t dbSNP:747692777
643 643 a, c, g dbSNP:779779259
644 644 a, g dbSNP:755323641
648 648 a, g dbSNP:141243848
650 650 a, g dbSNP:758223727
655 655 -, aaga dbSNP:772259613
656 656 -, a dbSNP:775417513
657 657 g, t dbSNP:750277149
668 668 a, c, g dbSNP:527843566
669 669 c, t dbSNP:576781299
677 677 a, g dbSNP:767707514
679 679 c, g dbSNP:760761804
681 681 a, g dbSNP:147790353
682 682 c, t dbSNP:752133294
691 691 c, t dbSNP:766808993
692 692 a, g dbSNP:149719695
695 695 c, t dbSNP:140807357
703 703 c, t dbSNP:769327758
720 720 a, t dbSNP:761532924
721 721 a, t dbSNP:151020233
730 730 c, t dbSNP:115463466
733 733 a, g dbSNP:139541965
736 736 g, t dbSNP:537314243
739 739 c, t dbSNP:746911409
740 740 a, g dbSNP:779938781
741 741 c, t dbSNP:772099944
744 744 a, g dbSNP:745641055
747 747 c, t dbSNP:778831301
752 752 a, g dbSNP:756220623
753 753 a, t dbSNP:752974306
754 754 g, t dbSNP:781368801
758 758 c, t dbSNP:376351866
761 761 a, c, t dbSNP:766971452
773 773 c, t dbSNP:763584348
773 773 -, t dbSNP:774761275
775 775 g, t dbSNP:568724445
776 776 a, c, g dbSNP:761325231
780 780 a, g dbSNP:776298663
786 786 -, a dbSNP:769660002
792 792 c, g dbSNP:768341160
795 795 c, t dbSNP:114706984
798 798 c, t dbSNP:775043863
800 800 a, g dbSNP:771895178
803 803 a, g dbSNP:373564630
813 813 a, g dbSNP:143560894
825 825 c, t dbSNP:764841347
826 826 -, cttt dbSNP:781221905
826 826 -, ct dbSNP:747983616
836 836 a, g dbSNP:370077923
843 843 a, g dbSNP:775478077
848 848 g, t dbSNP:781532109
850 850 c, t dbSNP:114127364
853 853 a, c dbSNP:751675958
854 854 g, t dbSNP:780186341
859 859 c, g dbSNP:769497610
877 877 c, t dbSNP:187613357
879 879 -, tcccc dbSNP:768705190
880 880 -, g dbSNP:747037935
883 883 a, c dbSNP:750964403
886 886 -, gtgatc dbSNP:757977872
888 888 c, t dbSNP:765480578
891 891 c, t dbSNP:757612378
900 900 c, g dbSNP:754253344
901 901 a, g dbSNP:763725995
917 917 g, t dbSNP:140080572
918 918 c, g dbSNP:774909282
923 923 c, t dbSNP:767064134
926 926 a, c dbSNP:759339103
933 933 c, t dbSNP:774374578
938 938 a, g dbSNP:770811946
939 939 c, t dbSNP:749068794
940 940 a, g dbSNP:773199170
944 944 -, a dbSNP:749996456
945 945 c, t dbSNP:759334506
946 946 a, g dbSNP:768933717
947 947 a, t dbSNP:747249411
953 953 -, t dbSNP:778568717
954 954 a, g dbSNP:776427090
959 959 g, t dbSNP:779950479
964 964 a, g dbSNP:758538643
972 972 c, t dbSNP:28933389
985 985 g, t dbSNP:779456773
989 989 c, t dbSNP:757823110
992 992 -, actg dbSNP:757549524
1004 1004 a, g dbSNP:746642541
1008 1008 a, g dbSNP:375775245
1009 1009 c, g dbSNP:16849700
1022 1022 a, g dbSNP:755701726
1023 1023 c, t dbSNP:752365776
1024 1024 a, c dbSNP:766894981
1030 1030 c, g dbSNP:759053642
1031 1031 a, t dbSNP:564041751
1038 1038 a, g dbSNP:766326312
1040 1040 a, t dbSNP:550866478
1044 1044 a, g dbSNP:115624085
1054 1054 a, g dbSNP:138271111
1055 1055 g, t dbSNP:747196387
1065 1065 c, t dbSNP:372593716
1086 1086 c, t dbSNP:775752216
1089 1089 a, g dbSNP:772234528
1094 1094 a, t dbSNP:114991020
1097 1097 c, t dbSNP:572660949
1098 1098 c, t dbSNP:771576791
1101 1101 g, t dbSNP:142586213
1118 1118 c, g dbSNP:749805953
1119 1119 c, t dbSNP:116607681
1120 1120 a, g dbSNP:368885671
1123 1123 c, g, t dbSNP:780873168
1124 1124 a, g dbSNP:754644618
1130 1130 a, g dbSNP:751075598
1147 1147 c, t dbSNP:766000843
1150 1150 a, g dbSNP:762936157
1152 1152 a, c dbSNP:150912772
1157 1157 a, g dbSNP:765307050
1164 1164 c, t dbSNP:104893684
1173 1173 a, g dbSNP:776350992
1180 1180 a, t dbSNP:557112656
1181 1181 a, t dbSNP:772337347
1182 1182 a, g dbSNP:759686297
1187 1187 -, acccagatt dbSNP:764498866
1187 1187 -, a dbSNP:754214624
1187 1187 a, t dbSNP:537434945
1198 1198 g, t dbSNP:771017682
1199 1199 a, g dbSNP:749752833
1213 1213 a, g dbSNP:778225256
1220 1220 a, g dbSNP:753657650
1227 1227 a, c dbSNP:770337031
1228 1228 a, t dbSNP:748533851
1229 1229 g, t dbSNP:781476667
1231 1231 c, t dbSNP:376091945
1232 1232 a, t dbSNP:121918557
1237 1237 c, t dbSNP:143300460
1238 1238 g, t dbSNP:201120931
1247 1247 c, t dbSNP:757948667
1250 1250 g, t dbSNP:750000733
1251 1251 c, g dbSNP:765249814
1255 1255 c, g dbSNP:139312740
1262 1262 -, g dbSNP:761080105
1263 1263 a, t dbSNP:753598758
1267 1267 -, caa dbSNP:753284945
1269 1269 a, g dbSNP:763806377
1289 1289 a, g dbSNP:534912670
1294 1294 c, t dbSNP:774590309
1297 1297 a, g dbSNP:372839550
1301 1301 a, g dbSNP:763000328
1302 1302 c, g, t dbSNP:373114728
1306 1306 a, c dbSNP:748608343
1310 1310 a, g dbSNP:146936556
1318 1318 -, t dbSNP:767469658
1331 1331 -, gagt dbSNP:759679732
1337 1337 c, g dbSNP:115129687
1338 1338 a, g dbSNP:747438953
1352 1352 c, t dbSNP:779828972
1355 1355 c, t dbSNP:760610944
1357 1357 -, t dbSNP:35979453
1358 1358 c, t dbSNP:758179631
1373 1373 c, g dbSNP:775490283
1377 1377 -, a dbSNP:768148788
1400 1400 c, t dbSNP:745364489
1401 1401 a, g dbSNP:778566503
1402 1402 c, t dbSNP:142671799
1406 1406 a, g dbSNP:753746052
1407 1407 c, t dbSNP:763914169
1413 1413 a, c, g, t dbSNP:28933390
1419 1419 c, t dbSNP:369207253
1427 1427 g, t dbSNP:773210938
1443 1443 a, g dbSNP:149097236
1444 1444 c, g dbSNP:762341786
1448 1448 g, t dbSNP:776972298
1449 1449 a, c dbSNP:562543522
1456 1456 a, g dbSNP:755959806
1462 1462 a, c, g dbSNP:780384860
1475 1475 a, c, g dbSNP:771781499
1479 1479 c, g dbSNP:539504704
1482 1482 a, g dbSNP:778513166
1484 1484 a, t dbSNP:369840366
1487 1487 a, c dbSNP:144987429
1489 1489 a, t dbSNP:570544890
1490 1490 a, g dbSNP:201490686
1492 1492 a, c dbSNP:756136656
1493 1493 a, t dbSNP:752486524
1503 1503 a, c dbSNP:767306248
1511 1511 c, g dbSNP:373022811
1513 1513 c, t dbSNP:267599673
1514 1514 c, t dbSNP:530517316
1523 1523 a, g dbSNP:765535291
1530 1530 c, g dbSNP:761774959
1531 1531 a, g dbSNP:369712135
1535 1535 a, c dbSNP:776827931
1547 1547 -, ctat dbSNP:763329644
1550 1550 a, g dbSNP:764502386
1551 1551 -, tg dbSNP:776566122
1551 1551 g, t dbSNP:761266167
1554 1554 -, a dbSNP:768538614
1557 1557 a, g dbSNP:775935293
1559 1559 a, g dbSNP:772583466
1560 1560 a, g dbSNP:745482363
1573 1573 a, g dbSNP:370506433
1579 1579 c, g dbSNP:377230118
1584 1584 g, t dbSNP:770669263
1585 1585 c, t dbSNP:372860529
1590 1590 c, t dbSNP:200151790
1591 1591 a, t dbSNP:769553145
1593 1593 c, t dbSNP:748092565
1598 1598 a, g dbSNP:150384913
1606 1606 a, t dbSNP:754736317
1610 1610 c, t dbSNP:751404124
1621 1621 c, t dbSNP:74458984
1622 1622 a, g dbSNP:200998515
1626 1626 a, g dbSNP:753791456
1642 1642 c, t dbSNP:764244573
1645 1645 a, g, t dbSNP:753283945
1649 1649 a, t dbSNP:768182433
1651 1651 a, t dbSNP:759961675
1652 1652 c, t dbSNP:115017300
1653 1653 a, g dbSNP:559088873
1659 1659 c, t dbSNP:762673285
1661 1661 a, c dbSNP:772540228
1664 1664 c, t dbSNP:769316835
1675 1675 c, t dbSNP:545580167
1677 1677 c, g, t dbSNP:532499978
1678 1678 g, t dbSNP:755486397
1685 1685 a, g dbSNP:752132070
1692 1692 c, g dbSNP:200768861
1704 1704 c, g dbSNP:371869257
1710 1710 a, g dbSNP:367912630
1712 1712 c, t dbSNP:755648929
1713 1713 a, g dbSNP:764864897
1715 1715 c, g dbSNP:761458446
1720 1720 c, t dbSNP:533603961
1734 1734 a, t dbSNP:121918556
1744 1744 a, t dbSNP:760485585
1749 1749 a, c dbSNP:371901966
1755 1755 a, g dbSNP:771956376
1773 1773 c, t dbSNP:77586249
1779 1779 c, t dbSNP:200817146
1780 1780 a, g dbSNP:774356916
1787 1787 c, t dbSNP:199660374
1788 1788 a, g dbSNP:374499560
1790 1790 c, g dbSNP:781374688
1799 1799 c, t dbSNP:755117040
1802 1802 c, t dbSNP:747099939
1803 1803 g, t dbSNP:780597019
1812 1812 c, t dbSNP:545173403
1813 1813 a, g dbSNP:750718617
1815 1815 c, t dbSNP:116333990
1817 1817 c, t dbSNP:756850483
1818 1818 a, t dbSNP:753517208
1822 1822 c, t dbSNP:116021719
1824 1824 a, c dbSNP:199551421
1828 1828 a, c dbSNP:763772612
1851 1851 c, t dbSNP:114166903
1855 1855 a, c, t dbSNP:778008893
1859 1859 a, g dbSNP:1803274
1860 1860 c, t dbSNP:752317854
1872 1872 a, g dbSNP:780715428
1875 1875 a, g dbSNP:151075873
1889 1889 c, t dbSNP:751164424
1890 1890 a, g, t dbSNP:762988755
1896 1896 a, g dbSNP:750175032
1897 1897 a, c dbSNP:764962053
1906 1906 c, g dbSNP:760910642
1916 1916 a, g dbSNP:775541959
1921 1921 c, t dbSNP:767826363
1927 1927 c, t dbSNP:759594959
1928 1928 a, g dbSNP:774484015
1929 1929 a, g dbSNP:199590217
1930 1930 c, t dbSNP:771363401
1931 1931 a, g dbSNP:749814210
1936 1936 -, cacta dbSNP:745387582
1941 1941 g, t dbSNP:142859898
1954 1954 c, t dbSNP:148569288
1958 1958 a, g, t dbSNP:373551373
1961 1961 g, t dbSNP:748586820
1962 1962 -, g dbSNP:535319263
1962 1962 g, t dbSNP:780688435
1976 1976 a, g dbSNP:754737274
1982 1982 c, t dbSNP:56084310
1995 1995 a, c dbSNP:779722552
2003 2003 c, t dbSNP:758361514
2005 2005 -, ttagatcaaggcaaaaat dbSNP:201751925
2006 2006 c, t dbSNP:750357744
2016 2016 a, c dbSNP:537887596
2025 2025 c, g dbSNP:191995340
2073 2073 c, g dbSNP:759407697
2101 2101 c, t dbSNP:556141230
2108 2108 a, t dbSNP:145327297
2131 2131 a, g dbSNP:567077263
2149 2149 a, g dbSNP:139885577
2158 2158 a, g dbSNP:3495
2159 2159 c, t dbSNP:55765003
2170 2170 a, g dbSNP:55781241
2175 2175 a, c dbSNP:1042406
2179 2179 c, t dbSNP:571279565
2218 2218 a, t dbSNP:150581482
2250 2250 a, c dbSNP:55753636
2254 2254 c, t dbSNP:55729116
2257 2257 -, t dbSNP:397762799
2257 2257 g, t dbSNP:371032418
2259 2259 -, g dbSNP:746868218
2262 2262 -, t, tt dbSNP:3836432
2263 2263 c, t dbSNP:199567692
2266 2266 c, t dbSNP:568512358
2284 2284 c, t dbSNP:369786680
2289 2289 c, t dbSNP:548870275
2297 2297 c, t dbSNP:529114188
2316 2316 a, c, t dbSNP:760760763
2318 2318 a, g dbSNP:55849903
2417 2417 c, t dbSNP:148490591
2424 2424 c, t dbSNP:187886111
2433 2433 a, t dbSNP:757059420
2436 2436 c, g dbSNP:144542474

Target ORF information:

RefSeq Version NM_000055
Organism Homo sapiens (human)
Definition Homo sapiens butyrylcholinesterase (BCHE), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_000055

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
ATGCATAGCA AAGTCACAAT CATATGCATC AGATTTCTCT TTTGGTTTCT TTTGCTCTGC 
ATGCTTATTG GGAAGTCACA TACTGAAGAT GACATCATAA TTGCAACAAA GAATGGAAAA
GTCAGAGGGA TGAACTTGAC AGTTTTTGGT GGCACGGTAA CAGCCTTTCT TGGAATTCCC
TATGCACAGC CACCTCTTGG TAGACTTCGA TTCAAAAAGC CACAGTCTCT GACCAAGTGG
TCTGATATTT GGAATGCCAC AAAATATGCA AATTCTTGCT GTCAGAACAT AGATCAAAGT
TTTCCAGGCT TCCATGGATC AGAGATGTGG AACCCAAACA CTGACCTCAG TGAAGACTGT
TTATATCTAA ATGTATGGAT TCCAGCACCT AAACCAAAAA ATGCCACTGT ATTGATATGG
ATTTATGGTG GTGGTTTTCA AACTGGAACA TCATCTTTAC ATGTTTATGA TGGCAAGTTT
CTGGCTCGGG TTGAAAGAGT TATTGTAGTG TCAATGAACT ATAGGGTGGG TGCCCTAGGA
TTCTTAGCTT TGCCAGGAAA TCCTGAGGCT CCAGGGAACA TGGGTTTATT TGATCAACAG
TTGGCTCTTC AGTGGGTTCA AAAAAATATA GCAGCCTTTG GTGGAAATCC TAAAAGTGTA
ACTCTCTTTG GAGAAAGTGC AGGAGCAGCT TCAGTTAGCC TGCATTTGCT TTCTCCTGGA
AGCCATTCAT TGTTCACCAG AGCCATTCTG CAAAGTGGAT CCTTTAATGC TCCTTGGGCG
GTAACATCTC TTTATGAAGC TAGGAACAGA ACGTTGAACT TAGCTAAATT GACTGGTTGC
TCTAGAGAGA ATGAGACTGA AATAATCAAG TGTCTTAGAA ATAAAGATCC CCAAGAAATT
CTTCTGAATG AAGCATTTGT TGTCCCCTAT GGGACTCCTT TGTCAGTAAA CTTTGGTCCG
ACCGTGGATG GTGATTTTCT CACTGACATG CCAGACATAT TACTTGAACT TGGACAATTT
AAAAAAACCC AGATTTTGGT GGGTGTTAAT AAAGATGAAG GGACAGCTTT TTTAGTCTAT
GGTGCTCCTG GCTTCAGCAA AGATAACAAT AGTATCATAA CTAGAAAAGA ATTTCAGGAA
GGTTTAAAAA TATTTTTTCC AGGAGTGAGT GAGTTTGGAA AGGAATCCAT CCTTTTTCAT
TACACAGACT GGGTAGATGA TCAGAGACCT GAAAACTACC GTGAGGCCTT GGGTGATGTT
GTTGGGGATT ATAATTTCAT ATGCCCTGCC TTGGAGTTCA CCAAGAAGTT CTCAGAATGG
GGAAATAATG CCTTTTTCTA CTATTTTGAA CACCGATCCT CCAAACTTCC GTGGCCAGAA
TGGATGGGAG TGATGCATGG CTATGAAATT GAATTTGTCT TTGGTTTACC TCTGGAAAGA
AGAGATAATT ACACAAAAGC CGAGGAAATT TTGAGTAGAT CCATAGTGAA ACGGTGGGCA
AATTTTGCAA AATATGGGAA TCCAAATGAG ACTCAGAACA ATAGCACAAG CTGGCCTGTC
TTCAAAAGCA CTGAACAAAA ATATCTAACC TTGAATACAG AGTCAACAAG AATAATGACG
AAACTACGTG CTCAACAATG TCGATTCTGG ACATCATTTT TTCCAAAAGT CTTGGAAATG
ACAGGAAATA TTGATGAAGC AGAATGGGAG TGGAAAGCAG GATTCCATCG CTGGAACAAT
TACATGATGG ACTGGAAAAA TCAATTTAAC GATTACACTA GCAAGAAAGA AAGTTGTGTG
GGTCTCTAA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.