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TNFRSF17 tumor necrosis factor receptor superfamily, member 17 [Homo sapiens (human)]

Gene Symbol TNFRSF17
Entrez Gene ID 608
Full Name tumor necrosis factor receptor superfamily, member 17
Synonyms BCM, BCMA, CD269, TNFRSF13A
General protein information
Preferred Names
tumor necrosis factor receptor superfamily member 17
Names
tumor necrosis factor receptor superfamily member 17
B-cell maturation factor
B cell maturation antigen
B-cell maturation protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

16

16p13.1

Summary The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

109545

Disorder Html:





The following TNFRSF17 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TNFRSF17 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu17157 NM_001192 Homo sapiens tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$69.3
$99

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu17157
Accession Version NM_001192.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 555bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product tumor necrosis factor receptor superfamily member 17
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from Z29575.1. On Sep 20, 2002 this sequence version replaced gi:4507572. Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Z29575.1, Z14954.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
ATGTTGCAGA TGGCTGGGCA GTGCTCCCAA AATGAATATT TTGACAGTTT GTTGCATGCT 
TGCATACCTT GTCAACTTCG ATGTTCTTCT AATACTCCTC CTCTAACATG TCAGCGTTAT
TGTAATGCAA GTGTGACCAA TTCAGTGAAA GGAACGAATG CGATTCTCTG GACCTGTTTG
GGACTGAGCT TAATAATTTC TTTGGCAGTT TTCGTGCTAA TGTTTTTGCT AAGGAAGATA
AACTCTGAAC CATTAAAGGA CGAGTTTAAA AACACAGGAT CAGGTCTCCT GGGCATGGCT
AACATTGACC TGGAAAAGAG CAGGACTGGT GATGAAATTA TTCTTCCGAG AGGCCTCGAG
TACACGGTGG AAGAATGCAC CTGTGAAGAC TGCATCAAGA GCAAACCGAA GGTCGACTCT
GACCATTGCT TTCCACTCCC AGCTATGGAG GAAGGCGCAA CCATTCTTGT CACCACGAAA
ACGAATGACT ATTGCAAGAG CCTGCCAGCT GCTTTGAGTG CTACGGAGAT AGAGAAATCA
ATTTCTGCTA GGTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001183.2
CDS219..773
Misc Feature(1)192..194(+)
Misc Feature(2)225..230(+)
Misc Feature(3)228..716(+)
Misc Feature(4)228..281(+)
Misc Feature(5)237..341(+)
Misc Feature(6)288..596(+)
Misc Feature(7)381..449(+)
Exon (1)1..348
Gene:TNFRSF17
Gene Synonym:
Exon (2)349..495
Gene:TNFRSF17
Gene Synonym:
Exon (3)496..994
Gene:TNFRSF17
Gene Synonym:
Translation
Position Chain Variation Link
7 7 -, aa dbSNP:781214857
43 43 c, t dbSNP:748411582
46 46 c, t dbSNP:769982992
56 56 c, t dbSNP:773622516
62 62 c, t dbSNP:192605606
69 69 a, g, t dbSNP:3743591
75 75 c, t dbSNP:11570139
87 87 a, c dbSNP:535227540
97 97 a, g dbSNP:558418776
126 126 c, t dbSNP:556321006
141 141 c, t dbSNP:578246359
151 151 c, t dbSNP:543780169
159 159 g, t dbSNP:151308896
172 172 c, g, t dbSNP:774729518
174 174 c, t dbSNP:556866997
197 197 c, t dbSNP:775728959
201 201 g, t dbSNP:760826489
214 214 a, c, t dbSNP:372620061
227 227 g, t dbSNP:762853349
229 229 c, t dbSNP:766104779
240 240 c, t dbSNP:751325020
241 241 a, g dbSNP:754875749
243 243 c, t dbSNP:767384244
251 251 c, t dbSNP:138231933
273 273 a, c dbSNP:375886084
275 275 g, t dbSNP:369340296
276 276 a, g dbSNP:143690193
278 278 c, t dbSNP:752221019
280 280 a, g dbSNP:756893990
282 282 a, c dbSNP:559017949
287 287 c, t dbSNP:746189405
294 294 a, c dbSNP:772767687
297 297 a, c, t dbSNP:185085849
298 298 a, g, t dbSNP:200779776
306 306 g, t dbSNP:190015454
313 313 -, ctc dbSNP:771579251
315 315 c, t dbSNP:118120349
320 320 -, tct dbSNP:749634242
332 332 c, g dbSNP:774030022
333 333 c, g, t dbSNP:550606391
334 334 g, t dbSNP:752610824
345 345 g, t dbSNP:760559467
355 355 a, c dbSNP:758071191
359 359 g, t dbSNP:780592053
360 360 g, t dbSNP:751904124
363 363 c, g dbSNP:575347463
369 369 c, g dbSNP:371280917
370 370 c, g dbSNP:748242648
373 373 a, c, t dbSNP:140266790
374 374 a, g dbSNP:749544407
378 378 a, g dbSNP:771077046
379 379 c, t dbSNP:11570146
380 380 a, g dbSNP:200361156
382 382 a, t dbSNP:768545253
388 388 a, g dbSNP:776302138
394 394 a, g, t dbSNP:150754620
401 401 a, c dbSNP:764823223
402 402 a, c dbSNP:772804388
403 403 g, t dbSNP:374829740
404 404 a, g dbSNP:766069132
409 409 -, taa dbSNP:771412919
411 411 a, g dbSNP:11570147
412 412 c, t dbSNP:368025520
418 418 c, g dbSNP:755364284
419 419 c, t dbSNP:767948470
431 431 c, t dbSNP:753224006
432 432 a, c, g, t dbSNP:146604927
436 436 -, taa dbSNP:753681360
441 441 c, g, t dbSNP:11570148
445 445 c, t dbSNP:779106309
449 449 -, aagg dbSNP:746891830
452 452 g, t dbSNP:746848257
456 456 -, ataaa dbSNP:768690894
457 457 a, c, t dbSNP:768479335
460 460 a, g dbSNP:373496
461 461 c, t dbSNP:769547668
468 468 c, g dbSNP:772859510
474 474 a, g dbSNP:17854965
475 475 a, c dbSNP:762535747
478 478 a, g dbSNP:375303867
479 479 c, g, t dbSNP:180992520
482 482 a, g dbSNP:767956136
483 483 a, t dbSNP:752937332
491 491 c, g dbSNP:756660154
492 492 a, t dbSNP:764572619
494 494 a, g dbSNP:373213400
495 495 a, g dbSNP:376683900
496 496 -, a dbSNP:764556231
496 496 g, t dbSNP:750572444
498 498 c, t dbSNP:762933989
503 503 c, t dbSNP:766663398
511 511 c, g dbSNP:751708019
512 512 c, t dbSNP:749695144
519 519 a, t dbSNP:371088184
523 523 c, t dbSNP:143855487
527 527 c, t dbSNP:201708971
528 528 c, t dbSNP:753629123
531 531 a, g dbSNP:757322532
537 537 a, g dbSNP:565143608
538 538 c, g dbSNP:778712592
541 541 c, g dbSNP:745425401
545 545 a, t dbSNP:756217244
548 548 c, t dbSNP:757826517
557 557 c, t dbSNP:779571230
565 565 c, t dbSNP:561432842
566 566 a, g dbSNP:768234958
572 572 -, cct dbSNP:754413067
575 575 c, g, t dbSNP:776988503
576 576 a, g dbSNP:770349402
579 579 c, t dbSNP:773558163
581 581 c, g dbSNP:146794298
583 583 c, t dbSNP:140545031
584 584 a, g, t dbSNP:183187632
587 587 a, g dbSNP:759841436
590 590 a, g dbSNP:767840692
591 591 g, t dbSNP:753754677
592 592 a, c dbSNP:540411283
595 595 a, g dbSNP:765271513
596 596 c, t dbSNP:750353416
598 598 c, t dbSNP:764270889
602 602 c, t dbSNP:779439057
609 609 c, t dbSNP:753836462
613 613 c, t dbSNP:746453732
614 614 c, g dbSNP:754679282
619 619 a, c, g dbSNP:780815996
620 620 a, c, g dbSNP:770030639
625 625 c, t dbSNP:374377405
626 626 a, g dbSNP:771402950
630 630 a, g dbSNP:199855585
631 631 c, t dbSNP:113898999
632 632 c, t dbSNP:759685287
633 633 a, c, g dbSNP:767893828
643 643 a, g dbSNP:760932832
651 651 c, t dbSNP:35682514
656 656 c, t dbSNP:750169105
661 661 c, t dbSNP:762815421
664 664 c, g, t dbSNP:151074854
673 673 a, g dbSNP:751132454
674 674 c, t dbSNP:35434482
675 675 a, g dbSNP:150352299
678 678 a, g dbSNP:752367622
686 686 c, t dbSNP:538420880
694 694 c, g, t dbSNP:755751031
695 695 a, g dbSNP:2017662
696 696 a, c dbSNP:771408651
701 701 a, g dbSNP:779532238
708 708 a, g, t dbSNP:200613750
712 712 c, g, t dbSNP:11570159
714 714 a, g dbSNP:768869498
723 723 a, c dbSNP:772934099
742 742 c, t dbSNP:371163866
743 743 a, g dbSNP:2071336
745 745 a, c dbSNP:751473650
746 746 c, g dbSNP:34546237
751 751 a, g dbSNP:767044556
752 752 a, g, t dbSNP:199882446
760 760 c, t dbSNP:777477440
762 762 c, t dbSNP:754195213
763 763 c, t dbSNP:757620574
767 767 c, t dbSNP:779373690
769 769 c, g dbSNP:746411502
772 772 a, t dbSNP:201838370
773 773 a, g dbSNP:772643010
775 775 c, t dbSNP:780297772
781 781 g, t dbSNP:547583575
784 784 c, t dbSNP:768823161
785 785 a, c, g dbSNP:374545778
789 789 c, g, t dbSNP:539311998
790 790 a, g dbSNP:376885863
792 792 a, g dbSNP:767384119
794 794 a, c dbSNP:774920489
795 795 a, g dbSNP:367581624
799 799 c, t dbSNP:763704315
802 802 c, t dbSNP:753552790
804 804 -, a dbSNP:757552584
804 804 c, t dbSNP:756823001
810 810 c, t dbSNP:765704717
823 823 c, t dbSNP:750763067
867 867 c, t dbSNP:113128674
889 889 c, g dbSNP:74008646
902 902 c, g dbSNP:747558553
948 948 c, t dbSNP:577200482
978 978 -, gt dbSNP:201064111
979 979 ctc, gtct dbSNP:71389075
979 979 c, g dbSNP:1126889
981 981 -, t dbSNP:113542863
981 981 c, t dbSNP:201687396
989 989 -, c, t dbSNP:34223679

Target ORF information:

RefSeq Version NM_001192
Organism Homo sapiens (human)
Definition Homo sapiens tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001192

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGTTGCAGA TGGCTGGGCA GTGCTCCCAA AATGAATATT TTGACAGTTT GTTGCATGCT 
TGCATACCTT GTCAACTTCG ATGTTCTTCT AATACTCCTC CTCTAACATG TCAGCGTTAT
TGTAATGCAA GTGTGACCAA TTCAGTGAAA GGAACGAATG CGATTCTCTG GACCTGTTTG
GGACTGAGCT TAATAATTTC TTTGGCAGTT TTCGTGCTAA TGTTTTTGCT AAGGAAGATA
AACTCTGAAC CATTAAAGGA CGAGTTTAAA AACACAGGAT CAGGTCTCCT GGGCATGGCT
AACATTGACC TGGAAAAGAG CAGGACTGGT GATGAAATTA TTCTTCCGAG AGGCCTCGAG
TACACGGTGG AAGAATGCAC CTGTGAAGAC TGCATCAAGA GCAAACCGAA GGTCGACTCT
GACCATTGCT TTCCACTCCC AGCTATGGAG GAAGGCGCAA CCATTCTTGT CACCACGAAA
ACGAATGACT ATTGCAAGAG CCTGCCAGCT GCTTTGAGTG CTACGGAGAT AGAGAAATCA
ATTTCTGCTA GGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.