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RPS10 cDNA ORF clone, Homo sapiens (human)

Gene Symbol RPS10
Entrez Gene ID 6204
Full Name ribosomal protein S10
Synonyms DBA9, S10
General protein information
Preferred Names
40S ribosomal protein S10
Names
40S ribosomal protein S10
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6p21.31

Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S10E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternate splicing results in multiple transcript variants that encode the same protein. Naturally occurring read-through transcription occurs between this locus and the neighboring locus NUDT3 (nudix (nucleoside diphosphate linked moiety X)-type motif 3).[provided by RefSeq, Feb 2011]. lac of sum
Disorder MIM:

603632

Disorder Html: Diamond-Blackfan anemia 9, 613308 (3)

mRNA and Protein(s)

mRNA Protein Name
NM_001014 NP_001005 40S ribosomal protein S10
NM_001203245 NP_001190174 40S ribosomal protein S10
NM_001204091 NP_001191020 40S ribosomal protein S10



Homo sapiens (human) RPS10 NP_001005.1
Pan troglodytes (chimpanzee) LOC742827 XP_003313051.1
Macaca mulatta (Rhesus monkey) RPS10 XP_001116498.1
Canis lupus familiaris (dog) RPS10 NP_001238974.1
Bos taurus (cattle) RPS10 NP_001029888.1
Mus musculus (house mouse) Rps10 NP_080239.1
Rattus norvegicus (Norway rat) Rps10l1 XP_002729669.1
Rattus norvegicus (Norway rat) Rps10 NP_112371.1
Gallus gallus (chicken) RPS10 NP_001244226.1
Drosophila melanogaster (fruit fly) RpS10a NP_651576.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following RPS10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPS10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu20633
NM_001014 Homo sapiens ribosomal protein S10 (RPS10), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu20633
NM_001203245 Homo sapiens ribosomal protein S10 (RPS10), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu20633
NM_001204091 Homo sapiens ribosomal protein S10 (RPS10), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu20633
Clone ID Related Accession (Same CDS sequence) NM_001014 , NM_001203245 , NM_001204091
Accession Version NM_001014.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 498bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product 40S ribosomal protein S10
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from BG940847.1, AL157372.18 and BC001032.2. This sequence is a reference standard in the RefSeqGene project. On Feb 5, 2011 this sequence version replaced gi:71164876. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BG028896.1, BU177770.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962337, SAMEA962346 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
ATGTTGATGC CTAAGAAGAA CCGGATTGCC ATTTATGAAC TCCTTTTTAA GGAGGGAGTC 
ATGGTGGCCA AGAAGGATGT CCACATGCCT AAGCACCCGG AGCTGGCAGA CAAGAATGTG
CCCAACCTTC ATGTCATGAA GGCCATGCAG TCTCTCAAGT CCCGAGGCTA CGTGAAGGAA
CAGTTTGCCT GGAGACATTT CTACTGGTAC CTTACCAATG AGGGTATCCA GTATCTCCGT
GATTACCTTC ATCTGCCCCC GGAGATTGTG CCTGCCACCC TACGCCGTAG CCGTCCAGAG
ACTGGCAGGC CTCGGCCTAA AGGTCTGGAG GGTGAGCGAC CTGCGAGACT CACAAGAGGG
GAAGCTGACA GAGATACCTA CAGACGGAGT GCTGTGCCAC CTGGTGCCGA CAAGAAAGCC
GAGGCTGGGG CTGGGTCAGC AACCGAATTC CAGTTTAGAG GCGGATTTGG TCGTGGACGT
GGTCAGCCAC CTCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001005.1
CDS95..592
Misc Feature(1)101..397(+)
Misc Feature(2)128..130(+)
Misc Feature(3)128..130(+)
Misc Feature(4)530..532(+)
Misc Feature(5)566..568(+)
Misc Feature(6)572..574(+)
Exon (1)1..94
Gene:RPS10
Gene Synonym:
Exon (2)95..244
Gene:RPS10
Gene Synonym:
Exon (3)245..416
Gene:RPS10
Gene Synonym:
Exon (4)417..494
Gene:RPS10
Gene Synonym:
Exon (5)495..550
Gene:RPS10
Gene Synonym:
Exon (6)551..644
Gene:RPS10
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001014
Organism Homo sapiens (human)
Definition Homo sapiens ribosomal protein S10 (RPS10), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001014

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGTTGATGC CTAAGAAGAA CCGGATTGCC ATTTATGAAC TCCTTTTTAA GGAGGGAGTC 
ATGGTGGCCA AGAAGGATGT CCACATGCCT AAGCACCCGG AGCTGGCAGA CAAGAATGTG
CCCAACCTTC ATGTCATGAA GGCCATGCAG TCTCTCAAGT CCCGAGGCTA CGTGAAGGAA
CAGTTTGCCT GGAGACATTT CTACTGGTAC CTTACCAATG AGGGTATCCA GTATCTCCGT
GATTACCTTC ATCTGCCCCC GGAGATTGTG CCTGCCACCC TACGCCGTAG CCGTCCAGAG
ACTGGCAGGC CTCGGCCTAA AGGTCTGGAG GGTGAGCGAC CTGCGAGACT CACAAGAGGG
GAAGCTGACA GAGATACCTA CAGACGGAGT GCTGTGCCAC CTGGTGCCGA CAAGAAAGCC
GAGGCTGGGG CTGGGTCAGC AACCGAATTC CAGTTTAGAG GCGGATTTGG TCGTGGACGT
GGTCAGCCAC CTCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20633
Clone ID Related Accession (Same CDS sequence) NM_001014 , NM_001203245 , NM_001204091
Accession Version NM_001203245.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 498bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product 40S ribosomal protein S10
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BG532491.1, AL157372.18 and BC071946.1. On Feb 11, 2011 this sequence version replaced gi:322303126. Transcript Variant: This variant (1) represents the longer transcript. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BQ894335.1, CK125962.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145245, SAMEA962337 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
ATGTTGATGC CTAAGAAGAA CCGGATTGCC ATTTATGAAC TCCTTTTTAA GGAGGGAGTC 
ATGGTGGCCA AGAAGGATGT CCACATGCCT AAGCACCCGG AGCTGGCAGA CAAGAATGTG
CCCAACCTTC ATGTCATGAA GGCCATGCAG TCTCTCAAGT CCCGAGGCTA CGTGAAGGAA
CAGTTTGCCT GGAGACATTT CTACTGGTAC CTTACCAATG AGGGTATCCA GTATCTCCGT
GATTACCTTC ATCTGCCCCC GGAGATTGTG CCTGCCACCC TACGCCGTAG CCGTCCAGAG
ACTGGCAGGC CTCGGCCTAA AGGTCTGGAG GGTGAGCGAC CTGCGAGACT CACAAGAGGG
GAAGCTGACA GAGATACCTA CAGACGGAGT GCTGTGCCAC CTGGTGCCGA CAAGAAAGCC
GAGGCTGGGG CTGGGTCAGC AACCGAATTC CAGTTTAGAG GCGGATTTGG TCGTGGACGT
GGTCAGCCAC CTCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001190174.1
CDS247..744
Misc Feature(1)226..228(+)
Misc Feature(2)253..549(+)
Misc Feature(3)718..720(+)
Misc Feature(4)724..726(+)
Exon (1)1..246
Gene:RPS10
Gene Synonym:
Exon (2)247..396
Gene:RPS10
Gene Synonym:
Exon (3)397..568
Gene:RPS10
Gene Synonym:
Exon (4)569..646
Gene:RPS10
Gene Synonym:
Exon (5)647..702
Gene:RPS10
Gene Synonym:
Exon (6)703..796
Gene:RPS10
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001203245
Organism Homo sapiens (human)
Definition Homo sapiens ribosomal protein S10 (RPS10), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001203245

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGTTGATGC CTAAGAAGAA CCGGATTGCC ATTTATGAAC TCCTTTTTAA GGAGGGAGTC 
ATGGTGGCCA AGAAGGATGT CCACATGCCT AAGCACCCGG AGCTGGCAGA CAAGAATGTG
CCCAACCTTC ATGTCATGAA GGCCATGCAG TCTCTCAAGT CCCGAGGCTA CGTGAAGGAA
CAGTTTGCCT GGAGACATTT CTACTGGTAC CTTACCAATG AGGGTATCCA GTATCTCCGT
GATTACCTTC ATCTGCCCCC GGAGATTGTG CCTGCCACCC TACGCCGTAG CCGTCCAGAG
ACTGGCAGGC CTCGGCCTAA AGGTCTGGAG GGTGAGCGAC CTGCGAGACT CACAAGAGGG
GAAGCTGACA GAGATACCTA CAGACGGAGT GCTGTGCCAC CTGGTGCCGA CAAGAAAGCC
GAGGCTGGGG CTGGGTCAGC AACCGAATTC CAGTTTAGAG GCGGATTTGG TCGTGGACGT
GGTCAGCCAC CTCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20633
Clone ID Related Accession (Same CDS sequence) NM_001014 , NM_001203245 , NM_001204091
Accession Version NM_001204091.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 498bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product 40S ribosomal protein S10
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL157372.18 and BU956627.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU956627.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145245 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
ATGTTGATGC CTAAGAAGAA CCGGATTGCC ATTTATGAAC TCCTTTTTAA GGAGGGAGTC 
ATGGTGGCCA AGAAGGATGT CCACATGCCT AAGCACCCGG AGCTGGCAGA CAAGAATGTG
CCCAACCTTC ATGTCATGAA GGCCATGCAG TCTCTCAAGT CCCGAGGCTA CGTGAAGGAA
CAGTTTGCCT GGAGACATTT CTACTGGTAC CTTACCAATG AGGGTATCCA GTATCTCCGT
GATTACCTTC ATCTGCCCCC GGAGATTGTG CCTGCCACCC TACGCCGTAG CCGTCCAGAG
ACTGGCAGGC CTCGGCCTAA AGGTCTGGAG GGTGAGCGAC CTGCGAGACT CACAAGAGGG
GAAGCTGACA GAGATACCTA CAGACGGAGT GCTGTGCCAC CTGGTGCCGA CAAGAAAGCC
GAGGCTGGGG CTGGGTCAGC AACCGAATTC CAGTTTAGAG GCGGATTTGG TCGTGGACGT
GGTCAGCCAC CTCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001191020.1
CDS99..596
Misc Feature(1)96..98(+)
Misc Feature(2)105..401(+)
Misc Feature(3)570..572(+)
Misc Feature(4)576..578(+)
Exon (1)1..98
Gene:RPS10
Gene Synonym:
Exon (2)99..248
Gene:RPS10
Gene Synonym:
Exon (3)249..420
Gene:RPS10
Gene Synonym:
Exon (4)421..498
Gene:RPS10
Gene Synonym:
Exon (5)499..554
Gene:RPS10
Gene Synonym:
Exon (6)555..648
Gene:RPS10
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001204091
Organism Homo sapiens (human)
Definition Homo sapiens ribosomal protein S10 (RPS10), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001204091

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGTTGATGC CTAAGAAGAA CCGGATTGCC ATTTATGAAC TCCTTTTTAA GGAGGGAGTC 
ATGGTGGCCA AGAAGGATGT CCACATGCCT AAGCACCCGG AGCTGGCAGA CAAGAATGTG
CCCAACCTTC ATGTCATGAA GGCCATGCAG TCTCTCAAGT CCCGAGGCTA CGTGAAGGAA
CAGTTTGCCT GGAGACATTT CTACTGGTAC CTTACCAATG AGGGTATCCA GTATCTCCGT
GATTACCTTC ATCTGCCCCC GGAGATTGTG CCTGCCACCC TACGCCGTAG CCGTCCAGAG
ACTGGCAGGC CTCGGCCTAA AGGTCTGGAG GGTGAGCGAC CTGCGAGACT CACAAGAGGG
GAAGCTGACA GAGATACCTA CAGACGGAGT GCTGTGCCAC CTGGTGCCGA CAAGAAAGCC
GAGGCTGGGG CTGGGTCAGC AACCGAATTC CAGTTTAGAG GCGGATTTGG TCGTGGACGT
GGTCAGCCAC CTCAGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

A novel mutation of ribosomal protein S10 gene in a Japanese patient with diamond-Blackfan anemia
J. Pediatr. Hematol. Oncol. 34 (4), 293-295 (2012)
Yazaki M, Kamei M, Ito Y, Konno Y, Wang R, Toki T and Ito E.


book

The HIV-1 Nef protein interacts with two components of the 40S small ribosomal subunit, the RPS10 protein and the 18S rRNA
Virol. J. 9, 103 (2012)
Abbas W, Dichamp I and Herbein G.


book

Methylation of ribosomal protein S10 by protein-arginine methyltransferase 5 regulates ribosome biogenesis
J. Biol. Chem. 285 (17), 12695-12705 (2010)
Ren J, Wang Y, Liang Y, Zhang Y, Bao S and Xu Z.


book

Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia
Am. J. Hum. Genet. 86 (2), 222-228 (2010)
Doherty L, Sheen MR, Vlachos A, Choesmel V, O'Donohue MF, Clinton C, Schneider HE, Sieff CA, Newburger PE, Ball SE, Niewiadomska E, Matysiak M, Glader B, Arceci RJ, Farrar JE, Atsidaftos E, Lipton JM, Gleizes PE and Gazda HT.


book

Proteins S7, S10, S16 and S19 of the human 40S ribosomal subunit are most resistant to dissociation by salt
Biochim. Biophys. Acta 1494 (3), 213-216 (2000)
Malygin AA, Shaulo DD and Karpova GG.


book

Pituitary tumor-transforming gene protein associates with ribosomal protein S10 and a novel human homologue of DnaJ in testicular cells
J. Biol. Chem. 274 (5), 3151-3158 (1999)
Pei L.


book

A map of 75 human ribosomal protein genes
Genome Res. 8 (5), 509-523 (1998)
Kenmochi N, Kawaguchi T, Rozen S, Davis E, Goodman N, Hudson TJ, Tanaka T and Page DC.


book

Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry
Eur. J. Biochem. 239 (1), 144-149 (1996)
Vladimirov SN, Ivanov AV, Karpova GG, Musolyamov AK, Egorov TA, Thiede B, Wittmann-Liebold B and Otto A.


book

Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs
Biochim. Biophys. Acta 1262 (1), 64-68 (1995)
Frigerio JM, Dagorn JC and Iovanna JL.


book

Diamond-Blackfan Anemia
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Clinton,C. and Gazda,H.T.


 
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