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RPS17 ribosomal protein S17 [Homo sapiens (human)]

Gene Symbol RPS17
Entrez Gene ID 6218
Full Name ribosomal protein S17
Synonyms DBA4, RPS17L, RPS17L1, RPS17L2, S17
General protein information
Preferred Names
40S ribosomal protein S17
Names
40S ribosomal protein S17
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

15

15q

Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S17E family of ribosomal proteins and is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia 4. Alternative splicing of this gene results in multiple transcript variants. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Apr 2014]. lac of sum
Disorder MIM:

180472

Disorder Html: Diamond-Blackfan anemia 4, 612527 (3)





The following RPS17 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RPS17 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu23517 NM_001021 Homo sapiens ribosomal protein S17 (RPS17), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$69.3
$99

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu23517
Accession Version NM_001021.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 408bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product 40S ribosomal protein S17
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Francesco Amaldi. The reference sequence was derived from BM017772.1, BC062715.1 and BE905890.1. On Apr 8, 2014 this sequence version replaced gi:71772428. Summary: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S17E family of ribosomal proteins and is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia 4. Alternative splicing of this gene results in multiple transcript variants. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Apr 2014]. Transcript Variant: This variant (1) encodes the supported protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI085304.1, BC062715.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
ATGGGCCGCG TTCGCACCAA AACCGTGAAG AAGGCGGCCC GGGTCATCAT AGAAAAGTAC 
TACACGCGCC TGGGCAACGA CTTCCACACG AACAAGCGCG TGTGCGAGGA GATCGCCATT
ATCCCCAGCA AAAAGCTCCG CAACAAGATA GCAGGTTATG TCACGCATCT GATGAAGCGA
ATTCAGAGAG GCCCAGTAAG AGGTATCTCC ATCAAGCTGC AGGAGGAGGA GAGAGAAAGG
AGAGACAATT ATGTTCCTGA GGTCTCAGCC TTGGATCAGG AGATTATTGA AGTAGATCCT
GACACTAAGG AAATGCTGAA GCTTTTGGAC TTCGGCAGTC TGTCCAACCT TCAGGTCACT
CAGCCTACAG TTGGGATGAA TTTCAAAACG CCTCGGGGAC CTGTTTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001012.1
CDS117..524
Misc Feature(1)57..59(+)
Misc Feature(2)117..482(+)
Misc Feature(3)453..455(+)
Misc Feature(4)453..455(+)
Misc Feature(5)504..506(+)
Exon (1)1..119
Gene:RPS17
Gene Synonym:
Exon (2)120..271
Gene:RPS17
Gene Synonym:
Exon (3)272..377
Gene:RPS17
Gene Synonym:
Exon (4)378..443
Gene:RPS17
Gene Synonym:
Exon (5)444..575
Gene:RPS17
Gene Synonym:
Translation
Position Chain Variation Link
85 85 c, t dbSNP:575115395
88 88 c, g dbSNP:762051874
93 93 c, t dbSNP:751731453
94 94 c, t dbSNP:764270175
103 103 a, t dbSNP:763087945
110 110 c, t dbSNP:775421410
116 116 a, c dbSNP:770348460
118 118 g, t dbSNP:116840811
275 275 c, g, t dbSNP:6991
316 316 -, ga dbSNP:116840812

Target ORF information:

RefSeq Version NM_001021
Organism Homo sapiens (human)
Definition Homo sapiens ribosomal protein S17 (RPS17), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001021

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGGCCGCG TTCGCACCAA AACCGTGAAG AAGGCGGCCC GGGTCATCAT AGAAAAGTAC 
TACACGCGCC TGGGCAACGA CTTCCACACG AACAAGCGCG TGTGCGAGGA GATCGCCATT
ATCCCCAGCA AAAAGCTCCG CAACAAGATA GCAGGTTATG TCACGCATCT GATGAAGCGA
ATTCAGAGAG GCCCAGTAAG AGGTATCTCC ATCAAGCTGC AGGAGGAGGA GAGAGAAAGG
AGAGACAATT ATGTTCCTGA GGTCTCAGCC TTGGATCAGG AGATTATTGA AGTAGATCCT
GACACTAAGG AAATGCTGAA GCTTTTGGAC TTCGGCAGTC TGTCCAACCT TCAGGTCACT
CAGCCTACAG TTGGGATGAA TTTCAAAACG CCTCGGGGAC CTGTTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.