The following RS1 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RS1 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 675bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from DQ426892.1, AF014459.1,
Z92542.2 and BQ185379.1.
This sequence is a reference standard in the RefSeqGene project.
On Sep 19, 2008 this sequence version replaced gi:56550120.
Summary: This gene encodes an extracellular protein that plays a
crucial role in the cellular organization of the retina. The
encoded protein is assembled and secreted from photoreceptors and
bipolar cells as a homo-oligomeric protein complex. Mutations in
this gene are responsible for X-linked retinoschisis, a common,
early-onset macular degeneration in males that results in a
splitting of the inner layers of the retina and severe loss in
vision. [provided by RefSeq, Oct 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: AF014459.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
COMPLETENESS: complete on the 3' end.