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BDNF brain-derived neurotrophic factor [Homo sapiens (human)]

Gene Symbol BDNF
Entrez Gene ID 627
Full Name brain-derived neurotrophic factor
Synonyms ANON2, BULN2
General protein information
Preferred Names
brain-derived neurotrophic factor
Names
brain-derived neurotrophic factor
abrineurin
neurotrophin
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11p13

Summary The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jan 2009]. lac of sum
Disorder MIM:

113505

Disorder Html: {Memory impairment, susceptibility to} (3); Central hypoventilation





The following BDNF gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BDNF gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu27396 NM_001143809 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 17, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199
OHu26594 NM_001143808 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 10, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$199
OHu26594 NM_001143807 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 9, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$199
OHu26594 NM_170735 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$269
OHu26730 NM_170734 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 6, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199
OHu26743 XM_011520280 PREDICTED: Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199
OHu27197 NM_170731 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199
OHu26594 NM_170732 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$199
OHu26594 NM_170733 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$269
OHu26594 NM_001709 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$269
OHu26594 NM_001143805 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 7, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$199
OHu26594 NM_001143806 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 8, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$199
OHu26743 NM_001143810 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 18, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $199
OHu26594 NM_001143811 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 11, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$199
OHu26594 NM_001143812 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 12, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$199
OHu26594 NM_001143813 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 13, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$199
OHu26594 NM_001143814 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 14, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$269
OHu26594 NM_001143816 Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 16, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$199

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu27396
Accession Version NM_001143809.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 831bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 25-MAY-2014
Organism Homo sapiens (human)
Product brain-derived neurotrophic factor isoform d preproprotein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from EF689012.1. Summary: The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jan 2009]. Transcript Variant: This variant (17), also known as Vb, represents use of an alternate promoter and differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (d) contains a longer N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF689012.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGCTCTGTG CGATTTCATT GTGTGCTCGC GTTCGCAAGC TCCGTAGTGC AGGAAGGTGC 
GGGAAGTTCC ACCAGGTGAG AAGAGTGATG ACCATCCTTT TCCTTACTAT GGTTATTTCA
TACTTTGGTT GCATGAAGGC TGCCCCCATG AAAGAAGCAA ACATCCGAGG ACAAGGTGGC
TTGGCCTACC CAGGTGTGCG GACCCATGGG ACTCTGGAGA GCGTGAATGG GCCCAAGGCA
GGTTCAAGAG GCTTGACATC ATTGGCTGAC ACTTTCGAAC ACGTGATAGA AGAGCTGTTG
GATGAGGACC AGAAAGTTCG GCCCAATGAA GAAAACAATA AGGACGCAGA CTTGTACACG
TCCAGGGTGA TGCTCAGTAG TCAAGTGCCT TTGGAGCCTC CTCTTCTCTT TCTGCTGGAG
GAATACAAAA ATTACCTAGA TGCTGCAAAC ATGTCCATGA GGGTCCGGCG CCACTCTGAC
CCTGCCCGCC GAGGGGAGCT GAGCGTGTGT GACAGTATTA GTGAGTGGGT AACGGCGGCA
GACAAAAAGA CTGCAGTGGA CATGTCGGGC GGGACGGTCA CAGTCCTTGA AAAGGTCCCT
GTATCAAAAG GCCAACTGAA GCAATACTTC TACGAGACCA AGTGCAATCC CATGGGTTAC
ACAAAAGAAG GCTGCAGGGG CATAGACAAA AGGCATTGGA ACTCCCAGTG CCGAACTACC
CAGTCGTACG TGCGGGCCCT TACCATGGAT AGCAAAAAGA GAATTGGCTG GCGATTCATA
AGGATAGACA CTTCTTGTGT ATGTACATTG ACCATTAAAA GGGGAAGATA G
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001137281.1
CDS18..848
Misc Feature(1)3..3(+)
Misc Feature(2)4..4(+)
Misc Feature(3)492..845(+)
Exon (1)1..83
Gene:BDNF
Gene Synonym:
Exon (2)84..3774
Gene:BDNF
Gene Synonym:
Translation
Position Chain Variation Link
10 10 c, t dbSNP:375796607
16 16 c, t dbSNP:748025933
19 19 c, t dbSNP:781253766
21 21 a, c dbSNP:758374320
36 36 c, t dbSNP:746006871
43 43 c, t dbSNP:778983778
48 48 g, t dbSNP:757430178
52 52 c, g dbSNP:754061487
56 56 a, c, g dbSNP:370909786
60 60 c, t dbSNP:753114863
66 66 a, g dbSNP:377250764
67 67 c, g dbSNP:759985000
75 75 g, t dbSNP:751074725
76 76 a, g dbSNP:765994816
80 80 a, g dbSNP:762641316
89 89 a, c dbSNP:780865517
109 109 a, c, t dbSNP:8192466
123 123 a, g dbSNP:779925777
143 143 c, t dbSNP:758200229
153 153 a, g dbSNP:750397219
174 174 a, g dbSNP:764254110
179 179 c, t dbSNP:760902255
183 183 c, t dbSNP:267602837
196 196 a, g, t dbSNP:767681787
213 213 a, g dbSNP:759834365
215 215 a, g dbSNP:374752426
216 216 c, t dbSNP:771341699
217 217 a, g dbSNP:763357890
225 225 c, g dbSNP:773773442
237 237 a, c dbSNP:769259549
239 239 c, t dbSNP:747701929
240 240 a, g dbSNP:146354977
248 248 a, g dbSNP:768158526
255 255 a, g dbSNP:746682028
260 260 c, t dbSNP:748122661
267 267 a, g dbSNP:779658522
274 274 c, t dbSNP:758274361
278 278 a, g dbSNP:529491621
293 293 c, t dbSNP:745797571
294 294 a, g dbSNP:779034534
299 299 c, t dbSNP:756240390
300 300 a, g dbSNP:6265
303 303 a, c dbSNP:767638736
313 313 a, t dbSNP:755097391
320 320 g, t dbSNP:201926642
325 325 a, g dbSNP:766646640
327 327 c, g dbSNP:139352447
329 329 g, t dbSNP:1048218
330 330 a, g dbSNP:372937141
337 337 a, g dbSNP:199638553
343 343 a, g dbSNP:370382246
354 354 a, g dbSNP:753561183
359 359 a, g dbSNP:776056344
362 362 c, t dbSNP:78675155
363 363 c, g dbSNP:746631679
368 368 c, t dbSNP:775282010
376 376 a, c, t dbSNP:745707481
377 377 a, g dbSNP:150767807
395 395 c, t dbSNP:757194182
397 397 a, g dbSNP:141477239
425 425 c, g dbSNP:148736382
427 427 a, t dbSNP:755151584
435 435 a, g dbSNP:751698045
443 443 c, t dbSNP:766669848
456 456 c, g dbSNP:758638310
458 458 c, t dbSNP:17852698
462 462 a, g dbSNP:766339291
467 467 c, t dbSNP:750743108
469 469 c, t dbSNP:765594245
474 474 a, c, t dbSNP:201119590
478 478 a, c dbSNP:1048220
479 479 a, g dbSNP:763510956
484 484 g, t dbSNP:1048221
516 516 a, c dbSNP:540912088
521 521 c, t dbSNP:760274076
522 522 a, g dbSNP:774985498
527 527 c, t dbSNP:771802172
551 551 a, g dbSNP:144235869
553 553 c, t dbSNP:774229943
554 554 a, g dbSNP:2353512
557 557 a, g dbSNP:749232626
560 560 c, t dbSNP:777804423
567 567 a, t dbSNP:201468555
569 569 g, t dbSNP:747058681
583 583 c, t dbSNP:750030464
584 584 a, g, t dbSNP:370102323
587 587 a, c, t dbSNP:376008850
592 592 c, t dbSNP:754270781
593 593 a, g dbSNP:764711746
599 599 a, t dbSNP:761108714
612 612 a, g, t dbSNP:77787410
635 635 a, g dbSNP:759249009
638 638 a, g dbSNP:774212958
650 650 c, t dbSNP:74975314
664 664 a, g dbSNP:762853361
669 669 a, c dbSNP:772901888
673 673 g, t dbSNP:769727156
683 683 a, g dbSNP:748036027
697 697 a, g dbSNP:780128716
698 698 a, c dbSNP:772201255
713 713 c, t dbSNP:746089117
719 719 c, t dbSNP:574936175
730 730 a, g dbSNP:757598331
734 734 c, t dbSNP:776524056
737 737 c, t dbSNP:778031646
743 743 a, g dbSNP:78572035
746 746 c, t dbSNP:138287649
750 750 a, c dbSNP:767130961
756 756 c, t dbSNP:759156741
758 758 g, t dbSNP:751233672
762 762 a, g dbSNP:766077652
767 767 c, t dbSNP:767047030
768 768 a, g dbSNP:762541432
789 789 a, c dbSNP:772989712
795 795 a, g dbSNP:764951525
804 804 a, g dbSNP:761800998
824 824 a, g dbSNP:776620062
831 831 a, g, t dbSNP:745999049
849 849 c, t dbSNP:761281403
860 860 c, t dbSNP:774437578
862 862 c, t dbSNP:771145439
871 871 -, gatta dbSNP:780624690
871 871 a, c, g dbSNP:778185724
872 872 a, g dbSNP:756500989
873 873 c, t dbSNP:748656340
875 875 -, atatt dbSNP:756542824
879 879 a, t dbSNP:781776605
884 884 -, caaaaatt dbSNP:767892799
888 888 -, aa dbSNP:751007747
894 894 -, ctat dbSNP:757951775
897 897 a, t dbSNP:541750774
943 943 -, t dbSNP:769564673
963 963 a, g dbSNP:574414545
974 974 g, t dbSNP:552714642
984 984 c, t dbSNP:534824375
1000 1000 -, t dbSNP:747480984
1014 1014 a, g dbSNP:142434530
1024 1024 aga, gt dbSNP:386752004
1024 1024 -, a dbSNP:538121499
1026 1026 a, t dbSNP:182639384
1028 1028 a, g dbSNP:753252926
1058 1058 a, c dbSNP:761860547
1068 1068 a, g dbSNP:573517244
1075 1075 c, t dbSNP:529348093
1098 1098 c, t dbSNP:148102034
1099 1099 a, g dbSNP:555245845
1136 1136 a, t dbSNP:551271356
1141 1141 a, c dbSNP:1048241
1198 1198 -, a dbSNP:397693902
1204 1204 a, c dbSNP:56820186
1237 1237 a, c dbSNP:190394666
1263 1263 -, agta dbSNP:771021204
1277 1277 c, t dbSNP:756576386
1289 1289 a, c dbSNP:546832995
1298 1298 a, t dbSNP:760016550
1347 1347 c, t dbSNP:528732267
1389 1389 a, g dbSNP:564017678
1420 1420 c, t dbSNP:769258981
1421 1421 a, g dbSNP:58597651
1435 1435 g, t dbSNP:41282918
1474 1474 c, t dbSNP:766704685
1497 1497 a, g dbSNP:530403605
1516 1516 a, g dbSNP:562917064
1539 1539 a, g dbSNP:114775469
1598 1598 g, t dbSNP:760827746
1643 1643 c, t dbSNP:574350764
1670 1670 a, g dbSNP:773522966
1688 1688 g, t dbSNP:77218393
1710 1710 -, c dbSNP:557827513
1712 1712 c, g dbSNP:540864354
1715 1715 a, c, g dbSNP:77500722
1737 1737 -, gtttt dbSNP:777469809
1762 1762 a, g dbSNP:557953714
1764 1764 a, g dbSNP:774487606
1780 1780 c, g dbSNP:770725317
1790 1790 g, t dbSNP:539948020
1801 1801 c, t dbSNP:79642557
1804 1804 a, g dbSNP:76327806
1817 1817 a, g dbSNP:535856866
1826 1826 a, g dbSNP:568768618
1845 1845 c, t dbSNP:547314136
1856 1856 -, t dbSNP:565661103
1865 1865 a, c dbSNP:779736202
1867 1867 a, g dbSNP:534890908
1871 1871 c, t dbSNP:571054679
1877 1877 a, g dbSNP:548123254
1878 1878 -, taa dbSNP:531946075
1885 1885 a, g dbSNP:755899586
1891 1891 a, g dbSNP:116594815
1894 1894 a, t dbSNP:530489347
1942 1942 a, t dbSNP:569421889
1950 1950 c, t dbSNP:187435518
1968 1968 a, c dbSNP:529687571
1991 1991 a, g dbSNP:745560630
2012 2012 c, t dbSNP:41282916
2025 2025 a, t dbSNP:756821763
2070 2070 a, g dbSNP:541348487
2080 2080 a, g dbSNP:532182640
2081 2081 a, g dbSNP:113432183
2090 2090 c, t dbSNP:546059446
2100 2100 -, c dbSNP:780391012
2101 2101 a, g dbSNP:543653872
2102 2102 c, g dbSNP:145801595
2108 2108 c, t dbSNP:143934500
2115 2115 a, c dbSNP:542237728
2124 2124 a, g dbSNP:574811557
2153 2153 a, g dbSNP:183097055
2215 2215 a, g dbSNP:755457172
2285 2285 a, g dbSNP:747657729
2291 2291 a, g dbSNP:535299323
2313 2313 c, t dbSNP:571074969
2314 2314 a, c, g dbSNP:559067547
2331 2331 c, t dbSNP:761065209
2366 2366 c, t dbSNP:773614587
2425 2425 -, taga dbSNP:771832956
2432 2432 c, t dbSNP:141418900
2446 2446 a, g dbSNP:146438590
2458 2458 c, t dbSNP:143957294
2539 2539 a, c dbSNP:529625211
2560 2560 c, g dbSNP:762051197
2629 2629 a, c dbSNP:11030100
2632 2632 g, t dbSNP:11030099
2636 2636 g, t dbSNP:532400006
2680 2680 c, g, t dbSNP:531923088
2706 2706 a, c dbSNP:191977070
2750 2750 c, t dbSNP:187665907
2788 2788 c, t dbSNP:373157604
2818 2818 c, t dbSNP:139209361
2845 2845 a, c dbSNP:542370882
2865 2865 -, t dbSNP:766060404
2943 2943 a, g dbSNP:574857700
3014 3014 a, t dbSNP:369836060
3017 3017 g, t dbSNP:377310701
3024 3024 c, g dbSNP:780893753
3034 3034 c, g dbSNP:552619701
3080 3080 -, aaga dbSNP:531999186
3090 3090 a, g dbSNP:368351549
3128 3128 a, c dbSNP:7124665
3149 3149 a, g dbSNP:150736756
3158 3158 a, g dbSNP:765431326
3174 3174 a, g dbSNP:7124442
3196 3196 c, t dbSNP:537972048
3231 3231 c, t dbSNP:41282914
3244 3244 a, c dbSNP:753967747
3254 3254 a, t dbSNP:180803886
3325 3325 a, g dbSNP:369617971
3405 3405 c, t dbSNP:80244532
3406 3406 c, t dbSNP:368036351
3407 3407 a, g dbSNP:754338213
3542 3542 c, g dbSNP:191137757
3557 3557 g, t dbSNP:547324985
3559 3559 a, g dbSNP:760691328
3572 3572 g, t dbSNP:3178739
3640 3640 -, a dbSNP:563108932
3658 3658 c, t dbSNP:538304747
3659 3659 c, t dbSNP:571512915
3660 3660 a, g dbSNP:543296443
3673 3673 c, t dbSNP:576161770
3681 3681 a, g dbSNP:557600370
3685 3685 a, g dbSNP:371776547
3715 3715 -, atata dbSNP:572229151

Target ORF information:

RefSeq Version NM_001143809
Organism Homo sapiens (human)
Definition Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 17, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001143809

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGCTCTGTG CGATTTCATT GTGTGCTCGC GTTCGCAAGC TCCGTAGTGC AGGAAGGTGC 
GGGAAGTTCC ACCAGGTGAG AAGAGTGATG ACCATCCTTT TCCTTACTAT GGTTATTTCA
TACTTTGGTT GCATGAAGGC TGCCCCCATG AAAGAAGCAA ACATCCGAGG ACAAGGTGGC
TTGGCCTACC CAGGTGTGCG GACCCATGGG ACTCTGGAGA GCGTGAATGG GCCCAAGGCA
GGTTCAAGAG GCTTGACATC ATTGGCTGAC ACTTTCGAAC ACGTGATAGA AGAGCTGTTG
GATGAGGACC AGAAAGTTCG GCCCAATGAA GAAAACAATA AGGACGCAGA CTTGTACACG
TCCAGGGTGA TGCTCAGTAG TCAAGTGCCT TTGGAGCCTC CTCTTCTCTT TCTGCTGGAG
GAATACAAAA ATTACCTAGA TGCTGCAAAC ATGTCCATGA GGGTCCGGCG CCACTCTGAC
CCTGCCCGCC GAGGGGAGCT GAGCGTGTGT GACAGTATTA GTGAGTGGGT AACGGCGGCA
GACAAAAAGA CTGCAGTGGA CATGTCGGGC GGGACGGTCA CAGTCCTTGA AAAGGTCCCT
GTATCAAAAG GCCAACTGAA GCAATACTTC TACGAGACCA AGTGCAATCC CATGGGTTAC
ACAAAAGAAG GCTGCAGGGG CATAGACAAA AGGCATTGGA ACTCCCAGTG CCGAACTACC
CAGTCGTACG TGCGGGCCCT TACCATGGAT AGCAAAAAGA GAATTGGCTG GCGATTCATA
AGGATAGACA CTTCTTGTGT ATGTACATTG ACCATTAAAA GGGGAAGATA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26594
Accession Version NM_001143808.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 744bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear Document: OHu26594D_COA.pdf (pdf)
Update Date 25-MAY-2014
Organism Homo sapiens (human)
Product brain-derived neurotrophic factor isoform a preproprotein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from EF689011.1. Summary: The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jan 2009]. Transcript Variant: This variant (10), also known as Va, differs in the 5' UTR and represents use of an alternate promoter compared to variant 1. Variants 1, 2, 4, 5, and 7-16 encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF689011.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACCATCC TTTTCCTTAC TATGGTTATT TCATACTTTG GTTGCATGAA GGCTGCCCCC 
ATGAAAGAAG CAAACATCCG AGGACAAGGT GGCTTGGCCT ACCCAGGTGT GCGGACCCAT
GGGACTCTGG AGAGCGTGAA TGGGCCCAAG GCAGGTTCAA GAGGCTTGAC ATCATTGGCT
GACACTTTCG AACACGTGAT AGAAGAGCTG TTGGATGAGG ACCAGAAAGT TCGGCCCAAT
GAAGAAAACA ATAAGGACGC AGACTTGTAC ACGTCCAGGG TGATGCTCAG TAGTCAAGTG
CCTTTGGAGC CTCCTCTTCT CTTTCTGCTG GAGGAATACA AAAATTACCT AGATGCTGCA
AACATGTCCA TGAGGGTCCG GCGCCACTCT GACCCTGCCC GCCGAGGGGA GCTGAGCGTG
TGTGACAGTA TTAGTGAGTG GGTAACGGCG GCAGACAAAA AGACTGCAGT GGACATGTCG
GGCGGGACGG TCACAGTCCT TGAAAAGGTC CCTGTATCAA AAGGCCAACT GAAGCAATAC
TTCTACGAGA CCAAGTGCAA TCCCATGGGT TACACAAAAG AAGGCTGCAG GGGCATAGAC
AAAAGGCATT GGAACTCCCA GTGCCGAACT ACCCAGTCGT ACGTGCGGGC CCTTACCATG
GATAGCAAAA AGAGAATTGG CTGGCGATTC ATAAGGATAG ACACTTCTTG TGTATGTACA
TTGACCATTA AAAGGGGAAG ATAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001137280.1
CDS95..838
Misc Feature(1)3..3(+)
Misc Feature(2)4..4(+)
Misc Feature(3)62..64(+)
Misc Feature(4)263..268(+)
Misc Feature(5)482..835(+)
Exon (1)1..73
Gene:BDNF
Gene Synonym:
Exon (2)74..3764
Gene:BDNF
Gene Synonym:
Translation
Position Chain Variation Link
10 10 c, t dbSNP:375796607
16 16 c, t dbSNP:748025933
19 19 c, t dbSNP:781253766
21 21 a, c dbSNP:758374320
36 36 c, t dbSNP:746006871
43 43 c, t dbSNP:778983778
48 48 g, t dbSNP:757430178
52 52 c, g dbSNP:754061487
56 56 a, c, g dbSNP:370909786
60 60 c, t dbSNP:753114863
66 66 a, g dbSNP:377250764
67 67 c, g dbSNP:759985000
79 79 a, c dbSNP:780865517
99 99 a, c, t dbSNP:8192466
113 113 a, g dbSNP:779925777
133 133 c, t dbSNP:758200229
143 143 a, g dbSNP:750397219
164 164 a, g dbSNP:764254110
169 169 c, t dbSNP:760902255
173 173 c, t dbSNP:267602837
186 186 a, g, t dbSNP:767681787
203 203 a, g dbSNP:759834365
205 205 a, g dbSNP:374752426
206 206 c, t dbSNP:771341699
207 207 a, g dbSNP:763357890
215 215 c, g dbSNP:773773442
227 227 a, c dbSNP:769259549
229 229 c, t dbSNP:747701929
230 230 a, g dbSNP:146354977
238 238 a, g dbSNP:768158526
245 245 a, g dbSNP:746682028
250 250 c, t dbSNP:748122661
257 257 a, g dbSNP:779658522
264 264 c, t dbSNP:758274361
268 268 a, g dbSNP:529491621
283 283 c, t dbSNP:745797571
284 284 a, g dbSNP:779034534
289 289 c, t dbSNP:756240390
290 290 a, g dbSNP:6265
293 293 a, c dbSNP:767638736
303 303 a, t dbSNP:755097391
310 310 g, t dbSNP:201926642
315 315 a, g dbSNP:766646640
317 317 c, g dbSNP:139352447
319 319 g, t dbSNP:1048218
320 320 a, g dbSNP:372937141
327 327 a, g dbSNP:199638553
333 333 a, g dbSNP:370382246
344 344 a, g dbSNP:753561183
349 349 a, g dbSNP:776056344
352 352 c, t dbSNP:78675155
353 353 c, g dbSNP:746631679
358 358 c, t dbSNP:775282010
366 366 a, c, t dbSNP:745707481
367 367 a, g dbSNP:150767807
385 385 c, t dbSNP:757194182
387 387 a, g dbSNP:141477239
415 415 c, g dbSNP:148736382
417 417 a, t dbSNP:755151584
425 425 a, g dbSNP:751698045
433 433 c, t dbSNP:766669848
446 446 c, g dbSNP:758638310
448 448 c, t dbSNP:17852698
452 452 a, g dbSNP:766339291
457 457 c, t dbSNP:750743108
459 459 c, t dbSNP:765594245
464 464 a, c, t dbSNP:201119590
468 468 a, c dbSNP:1048220
469 469 a, g dbSNP:763510956
474 474 g, t dbSNP:1048221
506 506 a, c dbSNP:540912088
511 511 c, t dbSNP:760274076
512 512 a, g dbSNP:774985498
517 517 c, t dbSNP:771802172
541 541 a, g dbSNP:144235869
543 543 c, t dbSNP:774229943
544 544 a, g dbSNP:2353512
547 547 a, g dbSNP:749232626
550 550 c, t dbSNP:777804423
557 557 a, t dbSNP:201468555
559 559 g, t dbSNP:747058681
573 573 c, t dbSNP:750030464
574 574 a, g, t dbSNP:370102323
577 577 a, c, t dbSNP:376008850
582 582 c, t dbSNP:754270781
583 583 a, g dbSNP:764711746
589 589 a, t dbSNP:761108714
602 602 a, g, t dbSNP:77787410
625 625 a, g dbSNP:759249009
628 628 a, g dbSNP:774212958
640 640 c, t dbSNP:74975314
654 654 a, g dbSNP:762853361
659 659 a, c dbSNP:772901888
663 663 g, t dbSNP:769727156
673 673 a, g dbSNP:748036027
687 687 a, g dbSNP:780128716
688 688 a, c dbSNP:772201255
703 703 c, t dbSNP:746089117
709 709 c, t dbSNP:574936175
720 720 a, g dbSNP:757598331
724 724 c, t dbSNP:776524056
727 727 c, t dbSNP:778031646
733 733 a, g dbSNP:78572035
736 736 c, t dbSNP:138287649
740 740 a, c dbSNP:767130961
746 746 c, t dbSNP:759156741
748 748 g, t dbSNP:751233672
752 752 a, g dbSNP:766077652
757 757 c, t dbSNP:767047030
758 758 a, g dbSNP:762541432
779 779 a, c dbSNP:772989712
785 785 a, g dbSNP:764951525
794 794 a, g dbSNP:761800998
814 814 a, g dbSNP:776620062
821 821 a, g, t dbSNP:745999049
839 839 c, t dbSNP:761281403
850 850 c, t dbSNP:774437578
852 852 c, t dbSNP:771145439
861 861 -, gatta dbSNP:780624690
861 861 a, c, g dbSNP:778185724
862 862 a, g dbSNP:756500989
863 863 c, t dbSNP:748656340
865 865 -, atatt dbSNP:756542824
869 869 a, t dbSNP:781776605
874 874 -, caaaaatt dbSNP:767892799
878 878 -, aa dbSNP:751007747
884 884 -, ctat dbSNP:757951775
887 887 a, t dbSNP:541750774
933 933 -, t dbSNP:769564673
953 953 a, g dbSNP:574414545
964 964 g, t dbSNP:552714642
974 974 c, t dbSNP:534824375
990 990 -, t dbSNP:747480984
1004 1004 a, g dbSNP:142434530
1014 1014 aga, gt dbSNP:386752004
1014 1014 -, a dbSNP:538121499
1016 1016 a, t dbSNP:182639384
1018 1018 a, g dbSNP:753252926
1048 1048 a, c dbSNP:761860547
1058 1058 a, g dbSNP:573517244
1065 1065 c, t dbSNP:529348093
1088 1088 c, t dbSNP:148102034
1089 1089 a, g dbSNP:555245845
1126 1126 a, t dbSNP:551271356
1131 1131 a, c dbSNP:1048241
1188 1188 -, a dbSNP:397693902
1194 1194 a, c dbSNP:56820186
1227 1227 a, c dbSNP:190394666
1253 1253 -, agta dbSNP:771021204
1267 1267 c, t dbSNP:756576386
1279 1279 a, c dbSNP:546832995
1288 1288 a, t dbSNP:760016550
1337 1337 c, t dbSNP:528732267
1379 1379 a, g dbSNP:564017678
1410 1410 c, t dbSNP:769258981
1411 1411 a, g dbSNP:58597651
1425 1425 g, t dbSNP:41282918
1464 1464 c, t dbSNP:766704685
1487 1487 a, g dbSNP:530403605
1506 1506 a, g dbSNP:562917064
1529 1529 a, g dbSNP:114775469
1588 1588 g, t dbSNP:760827746
1633 1633 c, t dbSNP:574350764
1660 1660 a, g dbSNP:773522966
1678 1678 g, t dbSNP:77218393
1700 1700 -, c dbSNP:557827513
1702 1702 c, g dbSNP:540864354
1705 1705 a, c, g dbSNP:77500722
1727 1727 -, gtttt dbSNP:777469809
1752 1752 a, g dbSNP:557953714
1754 1754 a, g dbSNP:774487606
1770 1770 c, g dbSNP:770725317
1780 1780 g, t dbSNP:539948020
1791 1791 c, t dbSNP:79642557
1794 1794 a, g dbSNP:76327806
1807 1807 a, g dbSNP:535856866
1816 1816 a, g dbSNP:568768618
1835 1835 c, t dbSNP:547314136
1846 1846 -, t dbSNP:565661103
1855 1855 a, c dbSNP:779736202
1857 1857 a, g dbSNP:534890908
1861 1861 c, t dbSNP:571054679
1867 1867 a, g dbSNP:548123254
1868 1868 -, taa dbSNP:531946075
1875 1875 a, g dbSNP:755899586
1881 1881 a, g dbSNP:116594815
1884 1884 a, t dbSNP:530489347
1932 1932 a, t dbSNP:569421889
1940 1940 c, t dbSNP:187435518
1958 1958 a, c dbSNP:529687571
1981 1981 a, g dbSNP:745560630
2002 2002 c, t dbSNP:41282916
2015 2015 a, t dbSNP:756821763
2060 2060 a, g dbSNP:541348487
2070 2070 a, g dbSNP:532182640
2071 2071 a, g dbSNP:113432183
2080 2080 c, t dbSNP:546059446
2090 2090 -, c dbSNP:780391012
2091 2091 a, g dbSNP:543653872
2092 2092 c, g dbSNP:145801595
2098 2098 c, t dbSNP:143934500
2105 2105 a, c dbSNP:542237728
2114 2114 a, g dbSNP:574811557
2143 2143 a, g dbSNP:183097055
2205 2205 a, g dbSNP:755457172
2275 2275 a, g dbSNP:747657729
2281 2281 a, g dbSNP:535299323
2303 2303 c, t dbSNP:571074969
2304 2304 a, c, g dbSNP:559067547
2321 2321 c, t dbSNP:761065209
2356 2356 c, t dbSNP:773614587
2415 2415 -, taga dbSNP:771832956
2422 2422 c, t dbSNP:141418900
2436 2436 a, g dbSNP:146438590
2448 2448 c, t dbSNP:143957294
2529 2529 a, c dbSNP:529625211
2550 2550 c, g dbSNP:762051197
2619 2619 a, c dbSNP:11030100
2622 2622 g, t dbSNP:11030099
2626 2626 g, t dbSNP:532400006
2670 2670 c, g, t dbSNP:531923088
2696 2696 a, c dbSNP:191977070
2740 2740 c, t dbSNP:187665907
2778 2778 c, t dbSNP:373157604
2808 2808 c, t dbSNP:139209361
2835 2835 a, c dbSNP:542370882
2855 2855 -, t dbSNP:766060404
2933 2933 a, g dbSNP:574857700
3004 3004 a, t dbSNP:369836060
3007 3007 g, t dbSNP:377310701
3014 3014 c, g dbSNP:780893753
3024 3024 c, g dbSNP:552619701
3070 3070 -, aaga dbSNP:531999186
3080 3080 a, g dbSNP:368351549
3118 3118 a, c dbSNP:7124665
3139 3139 a, g dbSNP:150736756
3148 3148 a, g dbSNP:765431326
3164 3164 a, g dbSNP:7124442
3186 3186 c, t dbSNP:537972048
3221 3221 c, t dbSNP:41282914
3234 3234 a, c dbSNP:753967747
3244 3244 a, t dbSNP:180803886
3315 3315 a, g dbSNP:369617971
3395 3395 c, t dbSNP:80244532
3396 3396 c, t dbSNP:368036351
3397 3397 a, g dbSNP:754338213
3532 3532 c, g dbSNP:191137757
3547 3547 g, t dbSNP:547324985
3549 3549 a, g dbSNP:760691328
3562 3562 g, t dbSNP:3178739
3630 3630 -, a dbSNP:563108932
3648 3648 c, t dbSNP:538304747
3649 3649 c, t dbSNP:571512915
3650 3650 a, g dbSNP:543296443
3663 3663 c, t dbSNP:576161770
3671 3671 a, g dbSNP:557600370
3675 3675 a, g dbSNP:371776547
3705 3705 -, atata dbSNP:572229151

Target ORF information:

RefSeq Version NM_001143808
Organism Homo sapiens (human)
Definition Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 10, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001143808

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACCATCC TTTTCCTTAC TATGGTTATT TCATACTTTG GTTGCATGAA GGCTGCCCCC 
ATGAAAGAAG CAAACATCCG AGGACAAGGT GGCTTGGCCT ACCCAGGTGT GCGGACCCAT
GGGACTCTGG AGAGCGTGAA TGGGCCCAAG GCAGGTTCAA GAGGCTTGAC ATCATTGGCT
GACACTTTCG AACACGTGAT AGAAGAGCTG TTGGATGAGG ACCAGAAAGT TCGGCCCAAT
GAAGAAAACA ATAAGGACGC AGACTTGTAC ACGTCCAGGG TGATGCTCAG TAGTCAAGTG
CCTTTGGAGC CTCCTCTTCT CTTTCTGCTG GAGGAATACA AAAATTACCT AGATGCTGCA
AACATGTCCA TGAGGGTCCG GCGCCACTCT GACCCTGCCC GCCGAGGGGA GCTGAGCGTG
TGTGACAGTA TTAGTGAGTG GGTAACGGCG GCAGACAAAA AGACTGCAGT GGACATGTCG
GGCGGGACGG TCACAGTCCT TGAAAAGGTC CCTGTATCAA AAGGCCAACT GAAGCAATAC
TTCTACGAGA CCAAGTGCAA TCCCATGGGT TACACAAAAG AAGGCTGCAG GGGCATAGAC
AAAAGGCATT GGAACTCCCA GTGCCGAACT ACCCAGTCGT ACGTGCGGGC CCTTACCATG
GATAGCAAAA AGAGAATTGG CTGGCGATTC ATAAGGATAG ACACTTCTTG TGTATGTACA
TTGACCATTA AAAGGGGAAG ATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26594
Accession Version NM_001143807.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 744bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear Document: OHu26594D_COA.pdf (pdf)
Update Date 25-MAY-2014
Organism Homo sapiens (human)
Product brain-derived neurotrophic factor isoform a preproprotein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from EF674520.1. Summary: The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jan 2009]. Transcript Variant: This variant (9), also known as III or BDNF3, differs in the 5' UTR and represents use of an alternate promoter compared to variant 1. Variants 1, 2, 4, 5, and 7-16 encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF674520.1, AY054396.2 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACCATCC TTTTCCTTAC TATGGTTATT TCATACTTTG GTTGCATGAA GGCTGCCCCC 
ATGAAAGAAG CAAACATCCG AGGACAAGGT GGCTTGGCCT ACCCAGGTGT GCGGACCCAT
GGGACTCTGG AGAGCGTGAA TGGGCCCAAG GCAGGTTCAA GAGGCTTGAC ATCATTGGCT
GACACTTTCG AACACGTGAT AGAAGAGCTG TTGGATGAGG ACCAGAAAGT TCGGCCCAAT
GAAGAAAACA ATAAGGACGC AGACTTGTAC ACGTCCAGGG TGATGCTCAG TAGTCAAGTG
CCTTTGGAGC CTCCTCTTCT CTTTCTGCTG GAGGAATACA AAAATTACCT AGATGCTGCA
AACATGTCCA TGAGGGTCCG GCGCCACTCT GACCCTGCCC GCCGAGGGGA GCTGAGCGTG
TGTGACAGTA TTAGTGAGTG GGTAACGGCG GCAGACAAAA AGACTGCAGT GGACATGTCG
GGCGGGACGG TCACAGTCCT TGAAAAGGTC CCTGTATCAA AAGGCCAACT GAAGCAATAC
TTCTACGAGA CCAAGTGCAA TCCCATGGGT TACACAAAAG AAGGCTGCAG GGGCATAGAC
AAAAGGCATT GGAACTCCCA GTGCCGAACT ACCCAGTCGT ACGTGCGGGC CCTTACCATG
GATAGCAAAA AGAGAATTGG CTGGCGATTC ATAAGGATAG ACACTTCTTG TGTATGTACA
TTGACCATTA AAAGGGGAAG ATAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001137279.1
CDS259..1002
Misc Feature(1)46..46(+)
Misc Feature(2)229..231(+)
Misc Feature(3)427..432(+)
Misc Feature(4)646..999(+)
Exon (1)1..237
Gene:BDNF
Gene Synonym:
Exon (2)238..3928
Gene:BDNF
Gene Synonym:
Translation
Position Chain Variation Link
54 54 c, t dbSNP:150504997
75 75 c, t dbSNP:554301099
100 100 c, t dbSNP:182538965
104 104 c, t dbSNP:538873289
131 131 c, g dbSNP:577635596
155 155 a, g dbSNP:183873737
177 177 a, g dbSNP:192499550
203 203 c, t dbSNP:2883187
234 234 c, t dbSNP:566921439
243 243 a, c dbSNP:780865517
263 263 a, c, t dbSNP:8192466
277 277 a, g dbSNP:779925777
297 297 c, t dbSNP:758200229
307 307 a, g dbSNP:750397219
328 328 a, g dbSNP:764254110
333 333 c, t dbSNP:760902255
337 337 c, t dbSNP:267602837
350 350 a, g, t dbSNP:767681787
367 367 a, g dbSNP:759834365
369 369 a, g dbSNP:374752426
370 370 c, t dbSNP:771341699
371 371 a, g dbSNP:763357890
379 379 c, g dbSNP:773773442
391 391 a, c dbSNP:769259549
393 393 c, t dbSNP:747701929
394 394 a, g dbSNP:146354977
402 402 a, g dbSNP:768158526
409 409 a, g dbSNP:746682028
414 414 c, t dbSNP:748122661
421 421 a, g dbSNP:779658522
428 428 c, t dbSNP:758274361
432 432 a, g dbSNP:529491621
447 447 c, t dbSNP:745797571
448 448 a, g dbSNP:779034534
453 453 c, t dbSNP:756240390
454 454 a, g dbSNP:6265
457 457 a, c dbSNP:767638736
467 467 a, t dbSNP:755097391
474 474 g, t dbSNP:201926642
479 479 a, g dbSNP:766646640
481 481 c, g dbSNP:139352447
483 483 g, t dbSNP:1048218
484 484 a, g dbSNP:372937141
491 491 a, g dbSNP:199638553
497 497 a, g dbSNP:370382246
508 508 a, g dbSNP:753561183
513 513 a, g dbSNP:776056344
516 516 c, t dbSNP:78675155
517 517 c, g dbSNP:746631679
522 522 c, t dbSNP:775282010
530 530 a, c, t dbSNP:745707481
531 531 a, g dbSNP:150767807
549 549 c, t dbSNP:757194182
551 551 a, g dbSNP:141477239
579 579 c, g dbSNP:148736382
581 581 a, t dbSNP:755151584
589 589 a, g dbSNP:751698045
597 597 c, t dbSNP:766669848
610 610 c, g dbSNP:758638310
612 612 c, t dbSNP:17852698
616 616 a, g dbSNP:766339291
621 621 c, t dbSNP:750743108
623 623 c, t dbSNP:765594245
628 628 a, c, t dbSNP:201119590
632 632 a, c dbSNP:1048220
633 633 a, g dbSNP:763510956
638 638 g, t dbSNP:1048221
670 670 a, c dbSNP:540912088
675 675 c, t dbSNP:760274076
676 676 a, g dbSNP:774985498
681 681 c, t dbSNP:771802172
705 705 a, g dbSNP:144235869
707 707 c, t dbSNP:774229943
708 708 a, g dbSNP:2353512
711 711 a, g dbSNP:749232626
714 714 c, t dbSNP:777804423
721 721 a, t dbSNP:201468555
723 723 g, t dbSNP:747058681
737 737 c, t dbSNP:750030464
738 738 a, g, t dbSNP:370102323
741 741 a, c, t dbSNP:376008850
746 746 c, t dbSNP:754270781
747 747 a, g dbSNP:764711746
753 753 a, t dbSNP:761108714
766 766 a, g, t dbSNP:77787410
789 789 a, g dbSNP:759249009
792 792 a, g dbSNP:774212958
804 804 c, t dbSNP:74975314
818 818 a, g dbSNP:762853361
823 823 a, c dbSNP:772901888
827 827 g, t dbSNP:769727156
837 837 a, g dbSNP:748036027
851 851 a, g dbSNP:780128716
852 852 a, c dbSNP:772201255
867 867 c, t dbSNP:746089117
873 873 c, t dbSNP:574936175
884 884 a, g dbSNP:757598331
888 888 c, t dbSNP:776524056
891 891 c, t dbSNP:778031646
897 897 a, g dbSNP:78572035
900 900 c, t dbSNP:138287649
904 904 a, c dbSNP:767130961
910 910 c, t dbSNP:759156741
912 912 g, t dbSNP:751233672
916 916 a, g dbSNP:766077652
921 921 c, t dbSNP:767047030
922 922 a, g dbSNP:762541432
943 943 a, c dbSNP:772989712
949 949 a, g dbSNP:764951525
958 958 a, g dbSNP:761800998
978 978 a, g dbSNP:776620062
985 985 a, g, t dbSNP:745999049
1003 1003 c, t dbSNP:761281403
1014 1014 c, t dbSNP:774437578
1016 1016 c, t dbSNP:771145439
1025 1025 -, gatta dbSNP:780624690
1025 1025 a, c, g dbSNP:778185724
1026 1026 a, g dbSNP:756500989
1027 1027 c, t dbSNP:748656340
1029 1029 -, atatt dbSNP:756542824
1033 1033 a, t dbSNP:781776605
1038 1038 -, caaaaatt dbSNP:767892799
1042 1042 -, aa dbSNP:751007747
1048 1048 -, ctat dbSNP:757951775
1051 1051 a, t dbSNP:541750774
1097 1097 -, t dbSNP:769564673
1117 1117 a, g dbSNP:574414545
1128 1128 g, t dbSNP:552714642
1138 1138 c, t dbSNP:534824375
1154 1154 -, t dbSNP:747480984
1168 1168 a, g dbSNP:142434530
1178 1178 aga, gt dbSNP:386752004
1178 1178 -, a dbSNP:538121499
1180 1180 a, t dbSNP:182639384
1182 1182 a, g dbSNP:753252926
1212 1212 a, c dbSNP:761860547
1222 1222 a, g dbSNP:573517244
1229 1229 c, t dbSNP:529348093
1252 1252 c, t dbSNP:148102034
1253 1253 a, g dbSNP:555245845
1290 1290 a, t dbSNP:551271356
1295 1295 a, c dbSNP:1048241
1352 1352 -, a dbSNP:397693902
1358 1358 a, c dbSNP:56820186
1391 1391 a, c dbSNP:190394666
1417 1417 -, agta dbSNP:771021204
1431 1431 c, t dbSNP:756576386
1443 1443 a, c dbSNP:546832995
1452 1452 a, t dbSNP:760016550
1501 1501 c, t dbSNP:528732267
1543 1543 a, g dbSNP:564017678
1574 1574 c, t dbSNP:769258981
1575 1575 a, g dbSNP:58597651
1589 1589 g, t dbSNP:41282918
1628 1628 c, t dbSNP:766704685
1651 1651 a, g dbSNP:530403605
1670 1670 a, g dbSNP:562917064
1693 1693 a, g dbSNP:114775469
1752 1752 g, t dbSNP:760827746
1797 1797 c, t dbSNP:574350764
1824 1824 a, g dbSNP:773522966
1842 1842 g, t dbSNP:77218393
1864 1864 -, c dbSNP:557827513
1866 1866 c, g dbSNP:540864354
1869 1869 a, c, g dbSNP:77500722
1891 1891 -, gtttt dbSNP:777469809
1916 1916 a, g dbSNP:557953714
1918 1918 a, g dbSNP:774487606
1934 1934 c, g dbSNP:770725317
1944 1944 g, t dbSNP:539948020
1955 1955 c, t dbSNP:79642557
1958 1958 a, g dbSNP:76327806
1971 1971 a, g dbSNP:535856866
1980 1980 a, g dbSNP:568768618
1999 1999 c, t dbSNP:547314136
2010 2010 -, t dbSNP:565661103
2019 2019 a, c dbSNP:779736202
2021 2021 a, g dbSNP:534890908
2025 2025 c, t dbSNP:571054679
2031 2031 a, g dbSNP:548123254
2032 2032 -, taa dbSNP:531946075
2039 2039 a, g dbSNP:755899586
2045 2045 a, g dbSNP:116594815
2048 2048 a, t dbSNP:530489347
2096 2096 a, t dbSNP:569421889
2104 2104 c, t dbSNP:187435518
2122 2122 a, c dbSNP:529687571
2145 2145 a, g dbSNP:745560630
2166 2166 c, t dbSNP:41282916
2179 2179 a, t dbSNP:756821763
2224 2224 a, g dbSNP:541348487
2234 2234 a, g dbSNP:532182640
2235 2235 a, g dbSNP:113432183
2244 2244 c, t dbSNP:546059446
2254 2254 -, c dbSNP:780391012
2255 2255 a, g dbSNP:543653872
2256 2256 c, g dbSNP:145801595
2262 2262 c, t dbSNP:143934500
2269 2269 a, c dbSNP:542237728
2278 2278 a, g dbSNP:574811557
2307 2307 a, g dbSNP:183097055
2369 2369 a, g dbSNP:755457172
2439 2439 a, g dbSNP:747657729
2445 2445 a, g dbSNP:535299323
2467 2467 c, t dbSNP:571074969
2468 2468 a, c, g dbSNP:559067547
2485 2485 c, t dbSNP:761065209
2520 2520 c, t dbSNP:773614587
2579 2579 -, taga dbSNP:771832956
2586 2586 c, t dbSNP:141418900
2600 2600 a, g dbSNP:146438590
2612 2612 c, t dbSNP:143957294
2693 2693 a, c dbSNP:529625211
2714 2714 c, g dbSNP:762051197
2783 2783 a, c dbSNP:11030100
2786 2786 g, t dbSNP:11030099
2790 2790 g, t dbSNP:532400006
2834 2834 c, g, t dbSNP:531923088
2860 2860 a, c dbSNP:191977070
2904 2904 c, t dbSNP:187665907
2942 2942 c, t dbSNP:373157604
2972 2972 c, t dbSNP:139209361
2999 2999 a, c dbSNP:542370882
3019 3019 -, t dbSNP:766060404
3097 3097 a, g dbSNP:574857700
3168 3168 a, t dbSNP:369836060
3171 3171 g, t dbSNP:377310701
3178 3178 c, g dbSNP:780893753
3188 3188 c, g dbSNP:552619701
3234 3234 -, aaga dbSNP:531999186
3244 3244 a, g dbSNP:368351549
3282 3282 a, c dbSNP:7124665
3303 3303 a, g dbSNP:150736756
3312 3312 a, g dbSNP:765431326
3328 3328 a, g dbSNP:7124442
3350 3350 c, t dbSNP:537972048
3385 3385 c, t dbSNP:41282914
3398 3398 a, c dbSNP:753967747
3408 3408 a, t dbSNP:180803886
3479 3479 a, g dbSNP:369617971
3559 3559 c, t dbSNP:80244532
3560 3560 c, t dbSNP:368036351
3561 3561 a, g dbSNP:754338213
3696 3696 c, g dbSNP:191137757
3711 3711 g, t dbSNP:547324985
3713 3713 a, g dbSNP:760691328
3726 3726 g, t dbSNP:3178739
3794 3794 -, a dbSNP:563108932
3812 3812 c, t dbSNP:538304747
3813 3813 c, t dbSNP:571512915
3814 3814 a, g dbSNP:543296443
3827 3827 c, t dbSNP:576161770
3835 3835 a, g dbSNP:557600370
3839 3839 a, g dbSNP:371776547
3869 3869 -, atata dbSNP:572229151

Target ORF information:

RefSeq Version NM_001143807
Organism Homo sapiens (human)
Definition Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 9, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001143807

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACCATCC TTTTCCTTAC TATGGTTATT TCATACTTTG GTTGCATGAA GGCTGCCCCC 
ATGAAAGAAG CAAACATCCG AGGACAAGGT GGCTTGGCCT ACCCAGGTGT GCGGACCCAT
GGGACTCTGG AGAGCGTGAA TGGGCCCAAG GCAGGTTCAA GAGGCTTGAC ATCATTGGCT
GACACTTTCG AACACGTGAT AGAAGAGCTG TTGGATGAGG ACCAGAAAGT TCGGCCCAAT
GAAGAAAACA ATAAGGACGC AGACTTGTAC ACGTCCAGGG TGATGCTCAG TAGTCAAGTG
CCTTTGGAGC CTCCTCTTCT CTTTCTGCTG GAGGAATACA AAAATTACCT AGATGCTGCA
AACATGTCCA TGAGGGTCCG GCGCCACTCT GACCCTGCCC GCCGAGGGGA GCTGAGCGTG
TGTGACAGTA TTAGTGAGTG GGTAACGGCG GCAGACAAAA AGACTGCAGT GGACATGTCG
GGCGGGACGG TCACAGTCCT TGAAAAGGTC CCTGTATCAA AAGGCCAACT GAAGCAATAC
TTCTACGAGA CCAAGTGCAA TCCCATGGGT TACACAAAAG AAGGCTGCAG GGGCATAGAC
AAAAGGCATT GGAACTCCCA GTGCCGAACT ACCCAGTCGT ACGTGCGGGC CCTTACCATG
GATAGCAAAA AGAGAATTGG CTGGCGATTC ATAAGGATAG ACACTTCTTG TGTATGTACA
TTGACCATTA AAAGGGGAAG ATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26594
Accession Version NM_170735.5 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 744bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear Document: OHu26594D_COA.pdf (pdf)
Update Date 26-MAY-2014
Organism Homo sapiens (human)
Product brain-derived neurotrophic factor isoform a preproprotein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from EF689009.1. On Jan 9, 2009 this sequence version replaced gi:60218885. Summary: The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jan 2009]. Transcript Variant: This variant (1), also known as IX, represents the longest transcript. Variants 1, 2, 4, 5, and 7-16 encode the same isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: EF689009.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACCATCC TTTTCCTTAC TATGGTTATT TCATACTTTG GTTGCATGAA GGCTGCCCCC 
ATGAAAGAAG CAAACATCCG AGGACAAGGT GGCTTGGCCT ACCCAGGTGT GCGGACCCAT
GGGACTCTGG AGAGCGTGAA TGGGCCCAAG GCAGGTTCAA GAGGCTTGAC ATCATTGGCT
GACACTTTCG AACACGTGAT AGAAGAGCTG TTGGATGAGG ACCAGAAAGT TCGGCCCAAT
GAAGAAAACA ATAAGGACGC AGACTTGTAC ACGTCCAGGG TGATGCTCAG TAGTCAAGTG
CCTTTGGAGC CTCCTCTTCT CTTTCTGCTG GAGGAATACA AAAATTACCT AGATGCTGCA
AACATGTCCA TGAGGGTCCG GCGCCACTCT GACCCTGCCC GCCGAGGGGA GCTGAGCGTG
TGTGACAGTA TTAGTGAGTG GGTAACGGCG GCAGACAAAA AGACTGCAGT GGACATGTCG
GGCGGGACGG TCACAGTCCT TGAAAAGGTC CCTGTATCAA AAGGCCAACT GAAGCAATAC
TTCTACGAGA CCAAGTGCAA TCCCATGGGT TACACAAAAG AAGGCTGCAG GGGCATAGAC
AAAAGGCATT GGAACTCCCA GTGCCGAACT ACCCAGTCGT ACGTGCGGGC CCTTACCATG
GATAGCAAAA AGAGAATTGG CTGGCGATTC ATAAGGATAG ACACTTCTTG TGTATGTACA
TTGACCATTA AAAGGGGAAG ATAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_733931.1
CDS1086..1829
Misc Feature(1)1026..1028(+)
Misc Feature(2)1254..1259(+)
Misc Feature(3)1254..1256(+)
Misc Feature(4)1473..1826(+)
Exon (1)1..4755
Gene:BDNF
Gene Synonym:
Translation
Position Chain Variation Link
1 1 -, gcac, gcacac dbSNP:756767477
2 2 a, g dbSNP:5790661
7 7 -, cc, gcacac dbSNP:765695151
10 10 -, ac, ca, cacaca dbSNP:55917552
19 19 c, g dbSNP:558014508
20 20 -, ca, cacaca dbSNP:149254890
21 21 c, g dbSNP:28722151
22 22 -, ag, ca, cacaca dbSNP:71449160
24 24 -, ga dbSNP:771535778
25 25 (cg)3(ca)12(ga)3, (cg)3(ca)2(cg)5(ca)10(ga)3, (cg)3(ca)2(cg)5(ca)11(ga)3, (cg)3(ca)2(cg)5(ca)12(ga)2, (cg)3(ca)2(cg)5(ca)13(ga)3, (cg)3(ca)2(cg)5(ca)9(ga)3, (cg)3a(ca)11(ga)2, cg(ca)2(cg)3a(ca)10(ga)2 dbSNP:45600637
25 25 -, ga dbSNP:773313661
26 26 a, g dbSNP:11267088
28 28 (ca)10, 11, 12, 13 dbSNP:376436923
43 43 c, g dbSNP:556698827
54 54 c, t dbSNP:184324828
75 75 a, g dbSNP:567419054
91 91 c, t dbSNP:375487206
92 92 a, g dbSNP:192802073
140 140 a, c dbSNP:527669869
152 152 c, t dbSNP:778868992
182 182 c, t dbSNP:566780310
207 207 c, t dbSNP:761731496
236 236 c, t dbSNP:551774663
247 247 a, c dbSNP:370977094
259 259 g, t dbSNP:754776265
267 267 a, t dbSNP:533424011
297 297 a, g dbSNP:144549848
310 310 c, t dbSNP:753566321
328 328 a, g dbSNP:149287030
391 391 -, gcaagtcttc dbSNP:57127302
397 397 a, c dbSNP:113353767
422 422 c, g dbSNP:772382280
438 438 c, t dbSNP:760288406
453 453 a, t dbSNP:11030101
460 460 g, t dbSNP:138656264
493 493 a, g dbSNP:925948
512 512 -, a dbSNP:781603284
535 535 a, g dbSNP:763475141
541 541 g, t dbSNP:570487681
542 542 c, t dbSNP:775935879
552 552 c, t dbSNP:770185772
570 570 a, g dbSNP:572919257
661 661 a, g dbSNP:150582127
662 662 c, t dbSNP:562228017
736 736 a, t dbSNP:543917051
816 816 a, g dbSNP:755515885
817 817 c, t dbSNP:76152614
830 830 a, g dbSNP:759800574
858 858 a, g dbSNP:568132062
862 862 a, c dbSNP:771057083
874 874 a, t dbSNP:575405185
952 952 a, g dbSNP:556884708
955 955 -, a dbSNP:539045662
972 972 c, t dbSNP:535262366
982 982 c, t dbSNP:376946177
1002 1002 c, t dbSNP:3750934
1011 1011 a, g dbSNP:534007890
1012 1012 -, g dbSNP:775142999
1016 1016 a, t dbSNP:373820825
1019 1019 a, g dbSNP:201522102
1021 1021 a, g dbSNP:772559051
1022 1022 g, t dbSNP:370087601
1030 1030 c, t dbSNP:376546912
1039 1039 a, g dbSNP:373416461
1042 1042 c, t dbSNP:771302662
1043 1043 g, t dbSNP:749807713
1044 1044 a, g dbSNP:777209031
1047 1047 c, t dbSNP:549934776
1058 1058 c, t dbSNP:551445385
1070 1070 a, c dbSNP:780865517
1090 1090 a, c, t dbSNP:8192466
1104 1104 a, g dbSNP:779925777
1124 1124 c, t dbSNP:758200229
1134 1134 a, g dbSNP:750397219
1155 1155 a, g dbSNP:764254110
1160 1160 c, t dbSNP:760902255
1164 1164 c, t dbSNP:267602837
1177 1177 a, g, t dbSNP:767681787
1194 1194 a, g dbSNP:759834365
1196 1196 a, g dbSNP:374752426
1197 1197 c, t dbSNP:771341699
1198 1198 a, g dbSNP:763357890
1206 1206 c, g dbSNP:773773442
1218 1218 a, c dbSNP:769259549
1220 1220 c, t dbSNP:747701929
1221 1221 a, g dbSNP:146354977
1229 1229 a, g dbSNP:768158526
1236 1236 a, g dbSNP:746682028
1241 1241 c, t dbSNP:748122661
1248 1248 a, g dbSNP:779658522
1255 1255 c, t dbSNP:758274361
1259 1259 a, g dbSNP:529491621
1274 1274 c, t dbSNP:745797571
1275 1275 a, g dbSNP:779034534
1280 1280 c, t dbSNP:756240390
1281 1281 a, g dbSNP:6265
1284 1284 a, c dbSNP:767638736
1294 1294 a, t dbSNP:755097391
1301 1301 g, t dbSNP:201926642
1306 1306 a, g dbSNP:766646640
1308 1308 c, g dbSNP:139352447
1310 1310 g, t dbSNP:1048218
1311 1311 a, g dbSNP:372937141
1318 1318 a, g dbSNP:199638553
1324 1324 a, g dbSNP:370382246
1335 1335 a, g dbSNP:753561183
1340 1340 a, g dbSNP:776056344
1343 1343 c, t dbSNP:78675155
1344 1344 c, g dbSNP:746631679
1349 1349 c, t dbSNP:775282010
1357 1357 a, c, t dbSNP:745707481
1358 1358 a, g dbSNP:150767807
1376 1376 c, t dbSNP:757194182
1378 1378 a, g dbSNP:141477239
1406 1406 c, g dbSNP:148736382
1408 1408 a, t dbSNP:755151584
1416 1416 a, g dbSNP:751698045
1424 1424 c, t dbSNP:766669848
1437 1437 c, g dbSNP:758638310
1439 1439 c, t dbSNP:17852698
1443 1443 a, g dbSNP:766339291
1448 1448 c, t dbSNP:750743108
1450 1450 c, t dbSNP:765594245
1455 1455 a, c, t dbSNP:201119590
1459 1459 a, c dbSNP:1048220
1460 1460 a, g dbSNP:763510956
1465 1465 g, t dbSNP:1048221
1497 1497 a, c dbSNP:540912088
1502 1502 c, t dbSNP:760274076
1503 1503 a, g dbSNP:774985498
1508 1508 c, t dbSNP:771802172
1532 1532 a, g dbSNP:144235869
1534 1534 c, t dbSNP:774229943
1535 1535 a, g dbSNP:2353512
1538 1538 a, g dbSNP:749232626
1541 1541 c, t dbSNP:777804423
1548 1548 a, t dbSNP:201468555
1550 1550 g, t dbSNP:747058681
1564 1564 c, t dbSNP:750030464
1565 1565 a, g, t dbSNP:370102323
1568 1568 a, c, t dbSNP:376008850
1573 1573 c, t dbSNP:754270781
1574 1574 a, g dbSNP:764711746
1580 1580 a, t dbSNP:761108714
1593 1593 a, g, t dbSNP:77787410
1616 1616 a, g dbSNP:759249009
1619 1619 a, g dbSNP:774212958
1631 1631 c, t dbSNP:74975314
1645 1645 a, g dbSNP:762853361
1650 1650 a, c dbSNP:772901888
1654 1654 g, t dbSNP:769727156
1664 1664 a, g dbSNP:748036027
1678 1678 a, g dbSNP:780128716
1679 1679 a, c dbSNP:772201255
1694 1694 c, t dbSNP:746089117
1700 1700 c, t dbSNP:574936175
1711 1711 a, g dbSNP:757598331
1715 1715 c, t dbSNP:776524056
1718 1718 c, t dbSNP:778031646
1724 1724 a, g dbSNP:78572035
1727 1727 c, t dbSNP:138287649
1731 1731 a, c dbSNP:767130961
1737 1737 c, t dbSNP:759156741
1739 1739 g, t dbSNP:751233672
1743 1743 a, g dbSNP:766077652
1748 1748 c, t dbSNP:767047030
1749 1749 a, g dbSNP:762541432
1770 1770 a, c dbSNP:772989712
1776 1776 a, g dbSNP:764951525
1785 1785 a, g dbSNP:761800998
1805 1805 a, g dbSNP:776620062
1812 1812 a, g, t dbSNP:745999049
1830 1830 c, t dbSNP:761281403
1841 1841 c, t dbSNP:774437578
1843 1843 c, t dbSNP:771145439
1852 1852 -, gatta dbSNP:780624690
1852 1852 a, c, g dbSNP:778185724
1853 1853 a, g dbSNP:756500989
1854 1854 c, t dbSNP:748656340
1856 1856 -, atatt dbSNP:756542824
1860 1860 a, t dbSNP:781776605
1865 1865 -, caaaaatt dbSNP:767892799
1869 1869 -, aa dbSNP:751007747
1875 1875 -, ctat dbSNP:757951775
1878 1878 a, t dbSNP:541750774
1924 1924 -, t dbSNP:769564673
1944 1944 a, g dbSNP:574414545
1955 1955 g, t dbSNP:552714642
1965 1965 c, t dbSNP:534824375
1981 1981 -, t dbSNP:747480984
1995 1995 a, g dbSNP:142434530
2005 2005 aga, gt dbSNP:386752004
2005 2005 -, a dbSNP:538121499
2007 2007 a, t dbSNP:182639384
2009 2009 a, g dbSNP:753252926
2039 2039 a, c dbSNP:761860547
2049 2049 a, g dbSNP:573517244
2056 2056 c, t dbSNP:529348093
2079 2079 c, t dbSNP:148102034
2080 2080 a, g dbSNP:555245845
2117 2117 a, t dbSNP:551271356
2122 2122 a, c dbSNP:1048241
2179 2179 -, a dbSNP:397693902
2185 2185 a, c dbSNP:56820186
2218 2218 a, c dbSNP:190394666
2244 2244 -, agta dbSNP:771021204
2258 2258 c, t dbSNP:756576386
2270 2270 a, c dbSNP:546832995
2279 2279 a, t dbSNP:760016550
2328 2328 c, t dbSNP:528732267
2370 2370 a, g dbSNP:564017678
2401 2401 c, t dbSNP:769258981
2402 2402 a, g dbSNP:58597651
2416 2416 g, t dbSNP:41282918
2455 2455 c, t dbSNP:766704685
2478 2478 a, g dbSNP:530403605
2497 2497 a, g dbSNP:562917064
2520 2520 a, g dbSNP:114775469
2579 2579 g, t dbSNP:760827746
2624 2624 c, t dbSNP:574350764
2651 2651 a, g dbSNP:773522966
2669 2669 g, t dbSNP:77218393
2691 2691 -, c dbSNP:557827513
2693 2693 c, g dbSNP:540864354
2696 2696 a, c, g dbSNP:77500722
2718 2718 -, gtttt dbSNP:777469809
2743 2743 a, g dbSNP:557953714
2745 2745 a, g dbSNP:774487606
2761 2761 c, g dbSNP:770725317
2771 2771 g, t dbSNP:539948020
2782 2782 c, t dbSNP:79642557
2785 2785 a, g dbSNP:76327806
2798 2798 a, g dbSNP:535856866
2807 2807 a, g dbSNP:568768618
2826 2826 c, t dbSNP:547314136
2837 2837 -, t dbSNP:565661103
2846 2846 a, c dbSNP:779736202
2848 2848 a, g dbSNP:534890908
2852 2852 c, t dbSNP:571054679
2858 2858 a, g dbSNP:548123254
2859 2859 -, taa dbSNP:531946075
2866 2866 a, g dbSNP:755899586
2872 2872 a, g dbSNP:116594815
2875 2875 a, t dbSNP:530489347
2923 2923 a, t dbSNP:569421889
2931 2931 c, t dbSNP:187435518
2949 2949 a, c dbSNP:529687571
2972 2972 a, g dbSNP:745560630
2993 2993 c, t dbSNP:41282916
3006 3006 a, t dbSNP:756821763
3051 3051 a, g dbSNP:541348487
3061 3061 a, g dbSNP:532182640
3062 3062 a, g dbSNP:113432183
3071 3071 c, t dbSNP:546059446
3081 3081 -, c dbSNP:780391012
3082 3082 a, g dbSNP:543653872
3083 3083 c, g dbSNP:145801595
3089 3089 c, t dbSNP:143934500
3096 3096 a, c dbSNP:542237728
3105 3105 a, g dbSNP:574811557
3134 3134 a, g dbSNP:183097055
3196 3196 a, g dbSNP:755457172
3266 3266 a, g dbSNP:747657729
3272 3272 a, g dbSNP:535299323
3294 3294 c, t dbSNP:571074969
3295 3295 a, c, g dbSNP:559067547
3312 3312 c, t dbSNP:761065209
3347 3347 c, t dbSNP:773614587
3406 3406 -, taga dbSNP:771832956
3413 3413 c, t dbSNP:141418900
3427 3427 a, g dbSNP:146438590
3439 3439 c, t dbSNP:143957294
3520 3520 a, c dbSNP:529625211
3541 3541 c, g dbSNP:762051197
3610 3610 a, c dbSNP:11030100
3613 3613 g, t dbSNP:11030099
3617 3617 g, t dbSNP:532400006
3661 3661 c, g, t dbSNP:531923088
3687 3687 a, c dbSNP:191977070
3731 3731 c, t dbSNP:187665907
3769 3769 c, t dbSNP:373157604
3799 3799 c, t dbSNP:139209361
3826 3826 a, c dbSNP:542370882
3846 3846 -, t dbSNP:766060404
3924 3924 a, g dbSNP:574857700
3995 3995 a, t dbSNP:369836060
3998 3998 g, t dbSNP:377310701
4005 4005 c, g dbSNP:780893753
4015 4015 c, g dbSNP:552619701
4061 4061 -, aaga dbSNP:531999186
4071 4071 a, g dbSNP:368351549
4109 4109 a, c dbSNP:7124665
4130 4130 a, g dbSNP:150736756
4139 4139 a, g dbSNP:765431326
4155 4155 a, g dbSNP:7124442
4177 4177 c, t dbSNP:537972048
4212 4212 c, t dbSNP:41282914
4225 4225 a, c dbSNP:753967747
4235 4235 a, t dbSNP:180803886
4306 4306 a, g dbSNP:369617971
4386 4386 c, t dbSNP:80244532
4387 4387 c, t dbSNP:368036351
4388 4388 a, g dbSNP:754338213
4523 4523 c, g dbSNP:191137757
4538 4538 g, t dbSNP:547324985
4540 4540 a, g dbSNP:760691328
4553 4553 g, t dbSNP:3178739
4621 4621 -, a dbSNP:563108932
4639 4639 c, t dbSNP:538304747
4640 4640 c, t dbSNP:571512915
4641 4641 a, g dbSNP:543296443
4654 4654 c, t dbSNP:576161770
4662 4662 a, g dbSNP:557600370
4666 4666 a, g dbSNP:371776547
4696 4696 -, atata dbSNP:572229151

Target ORF information:

RefSeq Version NM_170735
Organism Homo sapiens (human)
Definition Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_170735

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGACCATCC TTTTCCTTAC TATGGTTATT TCATACTTTG GTTGCATGAA GGCTGCCCCC 
ATGAAAGAAG CAAACATCCG AGGACAAGGT GGCTTGGCCT ACCCAGGTGT GCGGACCCAT
GGGACTCTGG AGAGCGTGAA TGGGCCCAAG GCAGGTTCAA GAGGCTTGAC ATCATTGGCT
GACACTTTCG AACACGTGAT AGAAGAGCTG TTGGATGAGG ACCAGAAAGT TCGGCCCAAT
GAAGAAAACA ATAAGGACGC AGACTTGTAC ACGTCCAGGG TGATGCTCAG TAGTCAAGTG
CCTTTGGAGC CTCCTCTTCT CTTTCTGCTG GAGGAATACA AAAATTACCT AGATGCTGCA
AACATGTCCA TGAGGGTCCG GCGCCACTCT GACCCTGCCC GCCGAGGGGA GCTGAGCGTG
TGTGACAGTA TTAGTGAGTG GGTAACGGCG GCAGACAAAA AGACTGCAGT GGACATGTCG
GGCGGGACGG TCACAGTCCT TGAAAAGGTC CCTGTATCAA AAGGCCAACT GAAGCAATAC
TTCTACGAGA CCAAGTGCAA TCCCATGGGT TACACAAAAG AAGGCTGCAG GGGCATAGAC
AAAAGGCATT GGAACTCCCA GTGCCGAACT ACCCAGTCGT ACGTGCGGGC CCTTACCATG
GATAGCAAAA AGAGAATTGG CTGGCGATTC ATAAGGATAG ACACTTCTTG TGTATGTACA
TTGACCATTA AAAGGGGAAG ATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26730
Accession Version NM_170734.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 789bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 25-MAY-2014
Organism Homo sapiens (human)
Product brain-derived neurotrophic factor isoform c preproprotein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from EF689018.1. On Jan 9, 2009 this sequence version replaced gi:34106709. Summary: The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jan 2009]. Transcript Variant: This variant (6), also known as VIIb, BDNF6B, or 4I-5, represents use of an alternate promoter and differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (c) contains a longer N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF689018.1, AB038674.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGCAGAGCC GGGAAGAGGA ATGGTTCCAC CAGGTGAGAA GAGTGATGAC CATCCTTTTC 
CTTACTATGG TTATTTCATA CTTTGGTTGC ATGAAGGCTG CCCCCATGAA AGAAGCAAAC
ATCCGAGGAC AAGGTGGCTT GGCCTACCCA GGTGTGCGGA CCCATGGGAC TCTGGAGAGC
GTGAATGGGC CCAAGGCAGG TTCAAGAGGC TTGACATCAT TGGCTGACAC TTTCGAACAC
GTGATAGAAG AGCTGTTGGA TGAGGACCAG AAAGTTCGGC CCAATGAAGA AAACAATAAG
GACGCAGACT TGTACACGTC CAGGGTGATG CTCAGTAGTC AAGTGCCTTT GGAGCCTCCT
CTTCTCTTTC TGCTGGAGGA ATACAAAAAT TACCTAGATG CTGCAAACAT GTCCATGAGG
GTCCGGCGCC ACTCTGACCC TGCCCGCCGA GGGGAGCTGA GCGTGTGTGA CAGTATTAGT
GAGTGGGTAA CGGCGGCAGA CAAAAAGACT GCAGTGGACA TGTCGGGCGG GACGGTCACA
GTCCTTGAAA AGGTCCCTGT ATCAAAAGGC CAACTGAAGC AATACTTCTA CGAGACCAAG
TGCAATCCCA TGGGTTACAC AAAAGAAGGC TGCAGGGGCA TAGACAAAAG GCATTGGAAC
TCCCAGTGCC GAACTACCCA GTCGTACGTG CGGGCCCTTA CCATGGATAG CAAAAAGAGA
ATTGGCTGGC GATTCATAAG GATAGACACT TCTTGTGTAT GTACATTGAC CATTAAAAGG
GGAAGATAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_733930.1
CDS262..1050
Misc Feature(1)250..252(+)
Misc Feature(2)430..432(+)
Misc Feature(3)694..1047(+)
Exon (1)1..285
Gene:BDNF
Gene Synonym:
Exon (2)286..3976
Gene:BDNF
Gene Synonym:
Translation
Position Chain Variation Link
6 6 a, g dbSNP:185565050
24 24 c, t dbSNP:764721789
31 31 a, t dbSNP:763551107
78 78 a, g dbSNP:753189823
138 138 c, g dbSNP:550032235
183 183 a, g dbSNP:538220947
214 214 c, t dbSNP:567592034
226 226 a, g dbSNP:749497650
227 227 c, g dbSNP:549261251
228 228 a, g dbSNP:756412814
228 228 -, g dbSNP:775265848
229 229 a, t dbSNP:753058303
231 231 a, g dbSNP:79679324
233 233 a, g dbSNP:200278157
234 234 c, g, t dbSNP:369725109
239 239 c, t dbSNP:762623064
245 245 a, c dbSNP:750064487
246 246 a, g dbSNP:376411831
248 248 c, g dbSNP:761390764
256 256 a, c dbSNP:776444181
268 268 a, t dbSNP:373221153
272 272 a, g dbSNP:760547277
277 277 a, c, g, t dbSNP:66866077
280 280 a, g dbSNP:770993324
284 284 a, g dbSNP:374218804
285 285 c, g, t dbSNP:777738330
291 291 a, c dbSNP:780865517
311 311 a, c, t dbSNP:8192466
325 325 a, g dbSNP:779925777
345 345 c, t dbSNP:758200229
355 355 a, g dbSNP:750397219
376 376 a, g dbSNP:764254110
381 381 c, t dbSNP:760902255
385 385 c, t dbSNP:267602837
398 398 a, g, t dbSNP:767681787
415 415 a, g dbSNP:759834365
417 417 a, g dbSNP:374752426
418 418 c, t dbSNP:771341699
419 419 a, g dbSNP:763357890
427 427 c, g dbSNP:773773442
439 439 a, c dbSNP:769259549
441 441 c, t dbSNP:747701929
442 442 a, g dbSNP:146354977
450 450 a, g dbSNP:768158526
457 457 a, g dbSNP:746682028
462 462 c, t dbSNP:748122661
469 469 a, g dbSNP:779658522
476 476 c, t dbSNP:758274361
480 480 a, g dbSNP:529491621
495 495 c, t dbSNP:745797571
496 496 a, g dbSNP:779034534
501 501 c, t dbSNP:756240390
502 502 a, g dbSNP:6265
505 505 a, c dbSNP:767638736
515 515 a, t dbSNP:755097391
522 522 g, t dbSNP:201926642
527 527 a, g dbSNP:766646640
529 529 c, g dbSNP:139352447
531 531 g, t dbSNP:1048218
532 532 a, g dbSNP:372937141
539 539 a, g dbSNP:199638553
545 545 a, g dbSNP:370382246
556 556 a, g dbSNP:753561183
561 561 a, g dbSNP:776056344
564 564 c, t dbSNP:78675155
565 565 c, g dbSNP:746631679
570 570 c, t dbSNP:775282010
578 578 a, c, t dbSNP:745707481
579 579 a, g dbSNP:150767807
597 597 c, t dbSNP:757194182
599 599 a, g dbSNP:141477239
627 627 c, g dbSNP:148736382
629 629 a, t dbSNP:755151584
637 637 a, g dbSNP:751698045
645 645 c, t dbSNP:766669848
658 658 c, g dbSNP:758638310
660 660 c, t dbSNP:17852698
664 664 a, g dbSNP:766339291
669 669 c, t dbSNP:750743108
671 671 c, t dbSNP:765594245
676 676 a, c, t dbSNP:201119590
680 680 a, c dbSNP:1048220
681 681 a, g dbSNP:763510956
686 686 g, t dbSNP:1048221
718 718 a, c dbSNP:540912088
723 723 c, t dbSNP:760274076
724 724 a, g dbSNP:774985498
729 729 c, t dbSNP:771802172
753 753 a, g dbSNP:144235869
755 755 c, t dbSNP:774229943
756 756 a, g dbSNP:2353512
759 759 a, g dbSNP:749232626
762 762 c, t dbSNP:777804423
769 769 a, t dbSNP:201468555
771 771 g, t dbSNP:747058681
785 785 c, t dbSNP:750030464
786 786 a, g, t dbSNP:370102323
789 789 a, c, t dbSNP:376008850
794 794 c, t dbSNP:754270781
795 795 a, g dbSNP:764711746
801 801 a, t dbSNP:761108714
814 814 a, g, t dbSNP:77787410
837 837 a, g dbSNP:759249009
840 840 a, g dbSNP:774212958
852 852 c, t dbSNP:74975314
866 866 a, g dbSNP:762853361
871 871 a, c dbSNP:772901888
875 875 g, t dbSNP:769727156
885 885 a, g dbSNP:748036027
899 899 a, g dbSNP:780128716
900 900 a, c dbSNP:772201255
915 915 c, t dbSNP:746089117
921 921 c, t dbSNP:574936175
932 932 a, g dbSNP:757598331
936 936 c, t dbSNP:776524056
939 939 c, t dbSNP:778031646
945 945 a, g dbSNP:78572035
948 948 c, t dbSNP:138287649
952 952 a, c dbSNP:767130961
958 958 c, t dbSNP:759156741
960 960 g, t dbSNP:751233672
964 964 a, g dbSNP:766077652
969 969 c, t dbSNP:767047030
970 970 a, g dbSNP:762541432
991 991 a, c dbSNP:772989712
997 997 a, g dbSNP:764951525
1006 1006 a, g dbSNP:761800998
1026 1026 a, g dbSNP:776620062
1033 1033 a, g, t dbSNP:745999049
1051 1051 c, t dbSNP:761281403
1062 1062 c, t dbSNP:774437578
1064 1064 c, t dbSNP:771145439
1073 1073 -, gatta dbSNP:780624690
1073 1073 a, c, g dbSNP:778185724
1074 1074 a, g dbSNP:756500989
1075 1075 c, t dbSNP:748656340
1077 1077 -, atatt dbSNP:756542824
1081 1081 a, t dbSNP:781776605
1086 1086 -, caaaaatt dbSNP:767892799
1090 1090 -, aa dbSNP:751007747
1096 1096 -, ctat dbSNP:757951775
1099 1099 a, t dbSNP:541750774
1145 1145 -, t dbSNP:769564673
1165 1165 a, g dbSNP:574414545
1176 1176 g, t dbSNP:552714642
1186 1186 c, t dbSNP:534824375
1202 1202 -, t dbSNP:747480984
1216 1216 a, g dbSNP:142434530
1226 1226 aga, gt dbSNP:386752004
1226 1226 -, a dbSNP:538121499
1228 1228 a, t dbSNP:182639384
1230 1230 a, g dbSNP:753252926
1260 1260 a, c dbSNP:761860547
1270 1270 a, g dbSNP:573517244
1277 1277 c, t dbSNP:529348093
1300 1300 c, t dbSNP:148102034
1301 1301 a, g dbSNP:555245845
1338 1338 a, t dbSNP:551271356
1343 1343 a, c dbSNP:1048241
1400 1400 -, a dbSNP:397693902
1406 1406 a, c dbSNP:56820186
1439 1439 a, c dbSNP:190394666
1465 1465 -, agta dbSNP:771021204
1479 1479 c, t dbSNP:756576386
1491 1491 a, c dbSNP:546832995
1500 1500 a, t dbSNP:760016550
1549 1549 c, t dbSNP:528732267
1591 1591 a, g dbSNP:564017678
1622 1622 c, t dbSNP:769258981
1623 1623 a, g dbSNP:58597651
1637 1637 g, t dbSNP:41282918
1676 1676 c, t dbSNP:766704685
1699 1699 a, g dbSNP:530403605
1718 1718 a, g dbSNP:562917064
1741 1741 a, g dbSNP:114775469
1800 1800 g, t dbSNP:760827746
1845 1845 c, t dbSNP:574350764
1872 1872 a, g dbSNP:773522966
1890 1890 g, t dbSNP:77218393
1912 1912 -, c dbSNP:557827513
1914 1914 c, g dbSNP:540864354
1917 1917 a, c, g dbSNP:77500722
1939 1939 -, gtttt dbSNP:777469809
1964 1964 a, g dbSNP:557953714
1966 1966 a, g dbSNP:774487606
1982 1982 c, g dbSNP:770725317
1992 1992 g, t dbSNP:539948020
2003 2003 c, t dbSNP:79642557
2006 2006 a, g dbSNP:76327806
2019 2019 a, g dbSNP:535856866
2028 2028 a, g dbSNP:568768618
2047 2047 c, t dbSNP:547314136
2058 2058 -, t dbSNP:565661103
2067 2067 a, c dbSNP:779736202
2069 2069 a, g dbSNP:534890908
2073 2073 c, t dbSNP:571054679
2079 2079 a, g dbSNP:548123254
2080 2080 -, taa dbSNP:531946075
2087 2087 a, g dbSNP:755899586
2093 2093 a, g dbSNP:116594815
2096 2096 a, t dbSNP:530489347
2144 2144 a, t dbSNP:569421889
2152 2152 c, t dbSNP:187435518
2170 2170 a, c dbSNP:529687571
2193 2193 a, g dbSNP:745560630
2214 2214 c, t dbSNP:41282916
2227 2227 a, t dbSNP:756821763
2272 2272 a, g dbSNP:541348487
2282 2282 a, g dbSNP:532182640
2283 2283 a, g dbSNP:113432183
2292 2292 c, t dbSNP:546059446
2302 2302 -, c dbSNP:780391012
2303 2303 a, g dbSNP:543653872
2304 2304 c, g dbSNP:145801595
2310 2310 c, t dbSNP:143934500
2317 2317 a, c dbSNP:542237728
2326 2326 a, g dbSNP:574811557
2355 2355 a, g dbSNP:183097055
2417 2417 a, g dbSNP:755457172
2487 2487 a, g dbSNP:747657729
2493 2493 a, g dbSNP:535299323
2515 2515 c, t dbSNP:571074969
2516 2516 a, c, g dbSNP:559067547
2533 2533 c, t dbSNP:761065209
2568 2568 c, t dbSNP:773614587
2627 2627 -, taga dbSNP:771832956
2634 2634 c, t dbSNP:141418900
2648 2648 a, g dbSNP:146438590
2660 2660 c, t dbSNP:143957294
2741 2741 a, c dbSNP:529625211
2762 2762 c, g dbSNP:762051197
2831 2831 a, c dbSNP:11030100
2834 2834 g, t dbSNP:11030099
2838 2838 g, t dbSNP:532400006
2882 2882 c, g, t dbSNP:531923088
2908 2908 a, c dbSNP:191977070
2952 2952 c, t dbSNP:187665907
2990 2990 c, t dbSNP:373157604
3020 3020 c, t dbSNP:139209361
3047 3047 a, c dbSNP:542370882
3067 3067 -, t dbSNP:766060404
3145 3145 a, g dbSNP:574857700
3216 3216 a, t dbSNP:369836060
3219 3219 g, t dbSNP:377310701
3226 3226 c, g dbSNP:780893753
3236 3236 c, g dbSNP:552619701
3282 3282 -, aaga dbSNP:531999186
3292 3292 a, g dbSNP:368351549
3330 3330 a, c dbSNP:7124665
3351 3351 a, g dbSNP:150736756
3360 3360 a, g dbSNP:765431326
3376 3376 a, g dbSNP:7124442
3398 3398 c, t dbSNP:537972048
3433 3433 c, t dbSNP:41282914
3446 3446 a, c dbSNP:753967747
3456 3456 a, t dbSNP:180803886
3527 3527 a, g dbSNP:369617971
3607 3607 c, t dbSNP:80244532
3608 3608 c, t dbSNP:368036351
3609 3609 a, g dbSNP:754338213
3744 3744 c, g dbSNP:191137757
3759 3759 g, t dbSNP:547324985
3761 3761 a, g dbSNP:760691328
3774 3774 g, t dbSNP:3178739
3842 3842 -, a dbSNP:563108932
3860 3860 c, t dbSNP:538304747
3861 3861 c, t dbSNP:571512915
3862 3862 a, g dbSNP:543296443
3875 3875 c, t dbSNP:576161770
3883 3883 a, g dbSNP:557600370
3887 3887 a, g dbSNP:371776547
3917 3917 -, atata dbSNP:572229151

Target ORF information:

RefSeq Version NM_170734
Organism Homo sapiens (human)
Definition Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant 6, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_170734

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGCAGAGCC GGGAAGAGGA ATGGTTCCAC CAGGTGAGAA GAGTGATGAC CATCCTTTTC 
CTTACTATGG TTATTTCATA CTTTGGTTGC ATGAAGGCTG CCCCCATGAA AGAAGCAAAC
ATCCGAGGAC AAGGTGGCTT GGCCTACCCA GGTGTGCGGA CCCATGGGAC TCTGGAGAGC
GTGAATGGGC CCAAGGCAGG TTCAAGAGGC TTGACATCAT TGGCTGACAC TTTCGAACAC
GTGATAGAAG AGCTGTTGGA TGAGGACCAG AAAGTTCGGC CCAATGAAGA AAACAATAAG
GACGCAGACT TGTACACGTC CAGGGTGATG CTCAGTAGTC AAGTGCCTTT GGAGCCTCCT
CTTCTCTTTC TGCTGGAGGA ATACAAAAAT TACCTAGATG CTGCAAACAT GTCCATGAGG
GTCCGGCGCC ACTCTGACCC TGCCCGCCGA GGGGAGCTGA GCGTGTGTGA CAGTATTAGT
GAGTGGGTAA CGGCGGCAGA CAAAAAGACT GCAGTGGACA TGTCGGGCGG GACGGTCACA
GTCCTTGAAA AGGTCCCTGT ATCAAAAGGC CAACTGAAGC AATACTTCTA CGAGACCAAG
TGCAATCCCA TGGGTTACAC AAAAGAAGGC TGCAGGGGCA TAGACAAAAG GCATTGGAAC
TCCCAGTGCC GAACTACCCA GTCGTACGTG CGGGCCCTTA CCATGGATAG CAAAAAGAGA
ATTGGCTGGC GATTCATAAG GATAGACACT TCTTGTGTAT GTACATTGAC CATTAAAAGG
GGAAGATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26743
Accession Version XM_011520280.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 990bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product brain-derived neurotrophic factor isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_009237.19) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTGTGGAG CCACCAGTTT TCTCCATGAG TGCACAAGGT TAATCCTTGT TACTACTCAG 
AATGCTGAGT TTCTACAGAA AGGGTTGCAG GTCCACACAT GTTTTGGCGT CTACCCACAC
GCTTCTGTAT GGCATGACTG TGCATCCCAG AAGAAGGGCT GTGCTGTGTA CCTCCACGTT
TCAGTGGAAT TTAACAAACT GATCCCTGAA AATGGTTTCA TAAAGTTCCA CCAGGTGAGA
AGAGTGATGA CCATCCTTTT CCTTACTATG GTTATTTCAT ACTTTGGTTG CATGAAGGCT
GCCCCCATGA AAGAAGCAAA CATCCGAGGA CAAGGTGGCT TGGCCTACCC AGGTGTGCGG
ACCCATGGGA CTCTGGAGAG CGTGAATGGG CCCAAGGCAG GTTCAAGAGG CTTGACATCA
TTGGCTGACA CTTTCGAACA CGTGATAGAA GAGCTGTTGG ATGAGGACCA GAAAGTTCGG
CCCAATGAAG AAAACAATAA GGACGCAGAC TTGTACACGT CCAGGGTGAT GCTCAGTAGT
CAAGTGCCTT TGGAGCCTCC TCTTCTCTTT CTGCTGGAGG AATACAAAAA TTACCTAGAT
GCTGCAAACA TGTCCATGAG GGTCCGGCGC CACTCTGACC CTGCCCGCCG AGGGGAGCTG
AGCGTGTGTG ACAGTATTAG TGAGTGGGTA ACGGCGGCAG ACAAAAAGAC TGCAGTGGAC
ATGTCGGGCG GGACGGTCAC AGTCCTTGAA AAGGTCCCTG TATCAAAAGG CCAACTGAAG
CAATACTTCT ACGAGACCAA GTGCAATCCC ATGGGTTACA CAAAAGAAGG CTGCAGGGGC
ATAGACAAAA GGCATTGGAA CTCCCAGTGC CGAACTACCC AGTCGTACGT GCGGGCCCTT
ACCATGGATA GCAAAAAGAG AATTGGCTGG CGATTCATAA GGATAGACAC TTCTTGTGTA
TGTACATTGA CCATTAAAAG GGGAAGATAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqXP_011518582.1
CDS1006..1995
Misc Feature(1)1639..1992(+)
Translation
Position Chain Variation Link
94 94 c, t dbSNP:142889786
106 106 a, g dbSNP:370064682
117 117 a, g dbSNP:377035349
149 149 c, t dbSNP:543908556
166 166 a, g dbSNP:753758646
183 183 c, t dbSNP:779909234
220 220 -, t, tatg dbSNP:561808071
278 278 a, g dbSNP:187439904
316 316 -, tgg dbSNP:148742587
366 366 -, ttt dbSNP:552203694
378 378 a, g dbSNP:755814821
439 439 c, t dbSNP:527556467
472 472 a, c dbSNP:771382101
477 477 a, g dbSNP:767058559
478 478 c, t dbSNP:749832004
502 502 g, t dbSNP:761449136
518 518 a, g dbSNP:75298795
519 519 g, t dbSNP:12291186
537 537 c, t dbSNP:367784915
541 541 g, t dbSNP:572405567
543 543 c, t dbSNP:374528026
628 628 c, t dbSNP:554000315
634 634 c, t dbSNP:760050759
676 676 c, t dbSNP:538962338
680 680 c, t dbSNP:377313604
688 688 a, g dbSNP:148532388
789 789 c, t dbSNP:368655717
798 798 c, t dbSNP:183683818
927 927 g, t dbSNP:10835210
963 963 a, c dbSNP:764682114
968 968 a, g dbSNP:147943376
972 972 a, c dbSNP:753445838
993 993 a, g dbSNP:368603984
1000 1000 a, g dbSNP:760530924
1003 1003 c, t dbSNP:775384015
1016 1016 c, g dbSNP:767394378
1017 1017 c, t dbSNP:759502897
1026 1026 c, t dbSNP:773278811
1033 1033 a, g dbSNP:769780489
1036 1036 c, t dbSNP:752297488
1041 1041 a, g dbSNP:748392649
1049 1049 -, taat dbSNP:747002774
1052 1052 c, t dbSNP:369607397
1071 1071 c, t dbSNP:769115694
1077 1077 -, gttt dbSNP:773125286
1088 1088 c, g dbSNP:747423302
1090 1090 c, t dbSNP:375110543
1095 1095 a, g dbSNP:773531757
1103 1103 c, t dbSNP:376102616
1104 1104 -, at dbSNP:539177035
1104 1104 a, g dbSNP:758930198
1105 1105 c, t dbSNP:746363872
1111 1111 -, cg dbSNP:748154574
1113 1113 c, t dbSNP:144776617
1114 1114 a, g dbSNP:756774056
1119 1119 c, t dbSNP:200573189
1123 1123 c, t dbSNP:763694071
1125 1125 c, t dbSNP:141032455
1126 1126 a, g dbSNP:752449726
1133 1133 -, t dbSNP:779216661
1135 1135 c, t dbSNP:767306218
1151 1151 c, g dbSNP:759413029
1154 1154 a, g dbSNP:774216055
1159 1159 -, aag dbSNP:755113936
1159 1159 a, g dbSNP:765357564
1172 1172 c, t dbSNP:551669106
1180 1180 c, t dbSNP:776885796
1182 1182 c, t dbSNP:779134556
1183 1183 a, g dbSNP:368243822
1192 1192 c, g dbSNP:775927167
1195 1195 c, t dbSNP:772577149
1206 1206 a, g dbSNP:746371320
1207 1207 a, t dbSNP:374758100
1218 1218 c, t dbSNP:770444228
1224 1224 a, c dbSNP:748698239
1230 1230 a, g dbSNP:777296944
1236 1236 a, c dbSNP:780865517
1256 1256 a, c, t dbSNP:8192466
1270 1270 a, g dbSNP:779925777
1290 1290 c, t dbSNP:758200229
1300 1300 a, g dbSNP:750397219
1321 1321 a, g dbSNP:764254110
1326 1326 c, t dbSNP:760902255
1330 1330 c, t dbSNP:267602837
1343 1343 a, g, t dbSNP:767681787
1360 1360 a, g dbSNP:759834365
1362 1362 a, g dbSNP:374752426
1363 1363 c, t dbSNP:771341699
1364 1364 a, g dbSNP:763357890
1372 1372 c, g dbSNP:773773442
1384 1384 a, c dbSNP:769259549
1386 1386 c, t dbSNP:747701929
1387 1387 a, g dbSNP:146354977
1395 1395 a, g dbSNP:768158526
1402 1402 a, g dbSNP:746682028
1407 1407 c, t dbSNP:748122661
1414 1414 a, g dbSNP:779658522
1421 1421 c, t dbSNP:758274361
1425 1425 a, g dbSNP:529491621
1440 1440 c, t dbSNP:745797571
1441 1441 a, g dbSNP:779034534
1446 1446 c, t dbSNP:756240390
1447 1447 a, g dbSNP:6265
1450 1450 a, c dbSNP:767638736
1460 1460 a, t dbSNP:755097391
1467 1467 g, t dbSNP:201926642
1472 1472 a, g dbSNP:766646640
1474 1474 c, g dbSNP:139352447
1476 1476 g, t dbSNP:1048218
1477 1477 a, g dbSNP:372937141
1484 1484 a, g dbSNP:199638553
1490 1490 a, g dbSNP:370382246
1501 1501 a, g dbSNP:753561183
1506 1506 a, g dbSNP:776056344
1509 1509 c, t dbSNP:78675155
1510 1510 c, g dbSNP:746631679
1515 1515 c, t dbSNP:775282010
1523 1523 a, c, t dbSNP:745707481
1524 1524 a, g dbSNP:150767807
1542 1542 c, t dbSNP:757194182
1544 1544 a, g dbSNP:141477239
1572 1572 c, g dbSNP:148736382
1574 1574 a, t dbSNP:755151584
1582 1582 a, g dbSNP:751698045
1590 1590 c, t dbSNP:766669848
1603 1603 c, g dbSNP:758638310
1605 1605 c, t dbSNP:17852698
1609 1609 a, g dbSNP:766339291
1614 1614 c, t dbSNP:750743108
1616 1616 c, t dbSNP:765594245
1621 1621 a, c, t dbSNP:201119590
1625 1625 a, c dbSNP:1048220
1626 1626 a, g dbSNP:763510956
1631 1631 g, t dbSNP:1048221
1663 1663 a, c dbSNP:540912088
1668 1668 c, t dbSNP:760274076
1669 1669 a, g dbSNP:774985498
1674 1674 c, t dbSNP:771802172
1698 1698 a, g dbSNP:144235869
1700 1700 c, t dbSNP:774229943
1701 1701 a, g dbSNP:2353512
1704 1704 a, g dbSNP:749232626
1707 1707 c, t dbSNP:777804423
1714 1714 a, t dbSNP:201468555
1716 1716 g, t dbSNP:747058681
1730 1730 c, t dbSNP:750030464
1731 1731 a, g, t dbSNP:370102323
1734 1734 a, c, t dbSNP:376008850
1739 1739 c, t dbSNP:754270781
1740 1740 a, g dbSNP:764711746
1746 1746 a, t dbSNP:761108714
1759 1759 a, g, t dbSNP:77787410
1782 1782 a, g dbSNP:759249009
1785 1785 a, g dbSNP:774212958
1797 1797 c, t dbSNP:74975314
1811 1811 a, g dbSNP:762853361
1816 1816 a, c dbSNP:772901888
1820 1820 g, t dbSNP:769727156
1830 1830 a, g dbSNP:748036027
1844 1844 a, g dbSNP:780128716
1845 1845 a, c dbSNP:772201255
1860 1860 c, t dbSNP:746089117
1866 1866 c, t dbSNP:574936175
1877 1877 a, g dbSNP:757598331
1881 1881 c, t dbSNP:776524056
1884 1884 c, t dbSNP:778031646
1890 1890 a, g dbSNP:78572035
1893 1893 c, t dbSNP:138287649
1897 1897 a, c dbSNP:767130961
1903 1903 c, t dbSNP:759156741
1905 1905 g, t dbSNP:751233672
1909 1909 a, g dbSNP:766077652
1914 1914 c, t dbSNP:767047030
1915 1915 a, g dbSNP:762541432
1936 1936 a, c dbSNP:772989712
1942 1942 a, g dbSNP:764951525
1951 1951 a, g dbSNP:761800998
1971 1971 a, g dbSNP:776620062
1978 1978 a, g, t dbSNP:745999049
1996 1996 c, t dbSNP:761281403
2007 2007 c, t dbSNP:774437578
2009 2009 c, t dbSNP:771145439
2018 2018 -, gatta dbSNP:780624690
2018 2018 a, c, g dbSNP:778185724
2019 2019 a, g dbSNP:756500989
2020 2020 c, t dbSNP:748656340
2022 2022 -, atatt dbSNP:756542824
2026 2026 a, t dbSNP:781776605
2031 2031 -, caaaaatt dbSNP:767892799
2035 2035 -, aa dbSNP:751007747
2041 2041 -, ctat dbSNP:757951775
2044 2044 a, t dbSNP:541750774
2090 2090 -, t dbSNP:769564673
2110 2110 a, g dbSNP:574414545
2121 2121 g, t dbSNP:552714642
2131 2131 c, t dbSNP:534824375
2147 2147 -, t dbSNP:747480984
2161 2161 a, g dbSNP:142434530
2171 2171 aga, gt dbSNP:386752004
2171 2171 -, a dbSNP:538121499
2173 2173 a, t dbSNP:182639384
2175 2175 a, g dbSNP:753252926
2205 2205 a, c dbSNP:761860547
2215 2215 a, g dbSNP:573517244
2222 2222 c, t dbSNP:529348093
2245 2245 c, t dbSNP:148102034
2246 2246 a, g dbSNP:555245845
2283 2283 a, t dbSNP:551271356
2288 2288 a, c dbSNP:1048241
2345 2345 -, a dbSNP:397693902
2351 2351 a, c dbSNP:56820186
2352 2352 -, a dbSNP:3838785
2385 2385 a, c dbSNP:190394666
2411 2411 -, agta dbSNP:771021204
2425 2425 c, t dbSNP:756576386
2437 2437 a, c dbSNP:546832995
2446 2446 a, t dbSNP:760016550
2495 2495 c, t dbSNP:528732267
2537 2537 a, g dbSNP:564017678
2568 2568 c, t dbSNP:769258981
2569 2569 a, g dbSNP:58597651
2583 2583 g, t dbSNP:41282918
2622 2622 c, t dbSNP:766704685
2645 2645 a, g dbSNP:530403605
2664 2664 a, g dbSNP:562917064
2687 2687 a, g dbSNP:114775469
2746 2746 g, t dbSNP:760827746
2791 2791 c, t dbSNP:574350764
2818 2818 a, g dbSNP:773522966
2836 2836 g, t dbSNP:77218393
2858 2858 -, c dbSNP:557827513
2860 2860 c, g dbSNP:540864354
2863 2863 a, c, g dbSNP:77500722
2885 2885 -, gtttt dbSNP:777469809
2910 2910 a, g dbSNP:557953714
2912 2912 a, g dbSNP:774487606
2928 2928 c, g dbSNP:770725317
2938 2938 g, t dbSNP:539948020
2949 2949 c, t dbSNP:79642557
2952 2952 a, g dbSNP:76327806
2965 2965 a, g dbSNP:535856866
2974 2974 a, g dbSNP:568768618
2993 2993 c, t dbSNP:547314136
3004 3004 -, t dbSNP:565661103
3013 3013 a, c dbSNP:779736202
3015 3015 a, g dbSNP:534890908
3019 3019 c, t dbSNP:571054679
3025 3025 a, g dbSNP:548123254
3026 3026 -, taa dbSNP:531946075
3033 3033 a, g dbSNP:755899586
3039 3039 a, g dbSNP:116594815
3042 3042 a, t dbSNP:530489347
3090 3090 a, t dbSNP:569421889
3098 3098 c, t dbSNP:187435518
3116 3116 a, c dbSNP:529687571
3139 3139 a, g dbSNP:745560630
3160 3160 c, t dbSNP:41282916
3173 3173 a, t dbSNP:756821763
3218 3218 a, g dbSNP:541348487
3228 3228 a, g dbSNP:532182640
3229 3229 a, g dbSNP:113432183
3238 3238 c, t dbSNP:546059446
3248 3248 -, c dbSNP:780391012
3249 3249 a, g dbSNP:543653872
3250 3250 c, g dbSNP:145801595
3256 3256 c, t dbSNP:143934500
3263 3263 a, c dbSNP:542237728
3272 3272 a, g dbSNP:574811557
3301 3301 a, g dbSNP:183097055
3363 3363 a, g dbSNP:755457172
3433 3433 a, g dbSNP:747657729
3439 3439 a, g dbSNP:535299323
3461 3461 c, t dbSNP:571074969
3462 3462 a, c, g dbSNP:559067547
3479 3479 c, t dbSNP:761065209
3514 3514 c, t dbSNP:773614587
3573 3573 -, taga dbSNP:771832956
3580 3580 c, t dbSNP:141418900
3594 3594 a, g dbSNP:146438590
3606 3606 c, t dbSNP:143957294
3687 3687 a, c dbSNP:529625211
3708 3708 c, g dbSNP:762051197
3777 3777 a, c dbSNP:11030100
3780 3780 g, t dbSNP:11030099
3784 3784 g, t dbSNP:532400006
3828 3828 c, g, t dbSNP:531923088
3854 3854 a, c dbSNP:191977070
3898 3898 c, t dbSNP:187665907
3936 3936 c, t dbSNP:373157604
3966 3966 c, t dbSNP:139209361
3993 3993 a, c dbSNP:542370882
4013 4013 -, t dbSNP:766060404
4091 4091 a, g dbSNP:574857700
4162 4162 a, t dbSNP:369836060
4165 4165 g, t dbSNP:377310701
4172 4172 c, g dbSNP:780893753
4182 4182 c, g dbSNP:552619701
4228 4228 -, aaga dbSNP:531999186
4238 4238 a, g dbSNP:368351549
4276 4276 a, c dbSNP:7124665
4297 4297 a, g dbSNP:150736756
4306 4306 a, g dbSNP:765431326
4322 4322 a, g dbSNP:7124442
4344 4344 c, t dbSNP:537972048
4379 4379 c, t dbSNP:41282914
4392 4392 a, c dbSNP:753967747
4402 4402 a, t dbSNP:180803886
4473 4473 a, g dbSNP:369617971
4553 4553 c, t dbSNP:80244532
4554 4554 c, t dbSNP:368036351
4555 4555 a, g dbSNP:754338213
4690 4690 c, g dbSNP:191137757
4705 4705 g, t dbSNP:547324985
4707 4707 a, g dbSNP:760691328
4720 4720 g, t dbSNP:3178739
4788 4788 -, a dbSNP:563108932
4806 4806 c, t dbSNP:538304747
4807 4807 c, t dbSNP:571512915
4808 4808 a, g dbSNP:543296443

Target ORF information:

RefSeq Version XM_011520280
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens brain-derived neurotrophic factor (BDNF), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011520280

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTGTGGAG CCACCAGTTT TCTCCATGAG TGCACAAGGT TAATCCTTGT TACTACTCAG 
AATGCTGAGT TTCTACAGAA AGGGTTGCAG GTCCACACAT GTTTTGGCGT CTACCCACAC
GCTTCTGTAT GGCATGACTG TGCATCCCAG AAGAAGGGCT GTGCTGTGTA CCTCCACGTT
TCAGTGGAAT TTAACAAACT GATCCCTGAA AATGGTTTCA TAAAGTTCCA CCAGGTGAGA
AGAGTGATGA CCATCCTTTT CCTTACTATG GTTATTTCAT ACTTTGGTTG CATGAAGGCT
GCCCCCATGA AAGAAGCAAA CATCCGAGGA CAAGGTGGCT TGGCCTACCC AGGTGTGCGG
ACCCATGGGA CTCTGGAGAG CGTGAATGGG CCCAAGGCAG GTTCAAGAGG CTTGACATCA
TTGGCTGACA CTTTCGAACA CGTGATAGAA GAGCTGTTGG ATGAGGACCA GAAAGTTCGG
CCCAATGAAG AAAACAATAA GGACGCAGAC TTGTACACGT CCAGGGTGAT GCTCAGTAGT
CAAGTGCCTT TGGAGCCTCC TCTTCTCTTT CTGCTGGAGG AATACAAAAA TTACCTAGAT
GCTGCAAACA TGTCCATGAG GGTCCGGCGC CACTCTGACC CTGCCCGCCG AGGGGAGCTG
AGCGTGTGTG ACAGTATTAG TGAGTGGGTA ACGGCGGCAG ACAAAAAGAC TGCAGTGGAC
ATGTCGGGCG GGACGGTCAC AGTCCTTGAA AAGGTCCCTG TATCAAAAGG CCAACTGAAG
CAATACTTCT ACGAGACCAA GTGCAATCCC ATGGGTTACA CAAAAGAAGG CTGCAGGGGC
ATAGACAAAA GGCATTGGAA CTCCCAGTGC CGAACTACCC AGTCGTACGT GCGGGCCCTT
ACCATGGATA GCAAAAAGAG AATTGGCTGG CGATTCATAA GGATAGACAC TTCTTGTGTA
TGTACATTGA CCATTAAAAG GGGAAGATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27197
Accession Version NM_170731.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 768bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector Document: User manual_GenEZ ORF Clone Products.pdf (pdf)
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags Document: MSDS_GenEZ ORF Clone Products.pdf (pdf)
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product brain-derived neurotrophic factor isoform b preproprotein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from EF689021.1. This sequence is a reference standard in the RefSeqGene project. On Jan 9, 2009 this sequence version replaced gi:60218883. Summary: The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jan 2009]. Transcript Variant: This variant (3), also known as I, BDNF1, or 1-5, represents use of an alternate promoter and differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (b) contains a longer N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: EF689021.1, AK289853.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGTTCCACC AGGTGAGAAG AGTGATGACC ATCCTTTTCC TTACTATGGT TATTTCATAC 
TTTGGTTGCA TGAAGGCTGC CCCCATGAAA GAAGCAAACA TCCGAGGACA AGGTGGCTTG
GCCTACCCAG GTGTGCGGAC CCATGGGACT CTGGAGAGCG TGAATGGGCC CAAGGCAGGT
TCAAGAGGCT TGACATCATT GGCTGACACT TTCGAACACG TGATAGAAGA GCTGTTGGAT
GAGGACCAGA AAGTTCGGCC CAATGAAGAA AACAATAAGG ACGCAGACTT GTACACGTCC
AGGGTGATGC TCAGTAGTCA AGTGCCTTTG GAGCCTCCTC TTCTCTTTCT GCTGGAGGAA
TACAAAAATT ACCTAGATGC TGCAAACATG TCCATGAGGG TCCGGCGCCA CTCTGACCCT
GCCCGCCGAG GGGAGCTGAG CGTGTGTGAC AGTATTAGTG AGTGGGTAAC GGCGGCAGAC
AAAAAGACTG CAGTGGACAT GTCGGGCGGG ACGGTCACAG TCCTTGAAAA GGTCCCTGTA
TCAAAAGGCC AACTGAAGCA ATACTTCTAC GAGACCAAGT GCAATCCCAT GGGTTACACA
AAAGAAGGCT GCAGGGGCAT AGACAAAAGG CATTGGAACT CCCAGTGCCG AACTACCCAG
TCGTACGTGC GGGCCCTTAC CATGGATAGC AAAAAGAGAA TTGGCTGGCG ATTCATAAGG
ATAGACACTT CTTGTGTATG TACATTGACC ATTAAAAGGG GAAGATAG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_733927.1
CDS645..1412
Misc Feature(1)219..219(+)
Misc Feature(2)531..533(+)
Misc Feature(3)837..839(+)
Misc Feature(4)1056..1409(+)
Exon (1)1..647
Gene:BDNF
Gene Synonym:
Exon (2)648..4338
Gene:BDNF
Gene Synonym:
Translation
Position Chain Variation Link
50 50 a, c dbSNP:28383487
111 111 c, t dbSNP:7929344
145 145 g, t dbSNP:756165762
153 153 c, t dbSNP:553451745
168 168 a, t dbSNP:574804602
176 176 a, g dbSNP:767601477
185 185 a, g dbSNP:74407580
186 186 c, g, t dbSNP:77559845
186 186 -, t dbSNP:397738894
188 188 c, t dbSNP:558731195
196 196 -, t dbSNP:34578636
197 197 a, t dbSNP:765062545
203 203 g, t dbSNP:200131453
214 214 c, t dbSNP:761836907
220 220 a, c dbSNP:751456620
229 229 c, g dbSNP:753571099
257 257 a, c dbSNP:763992661
265 265 g, t dbSNP:762744495
273 273 a, c dbSNP:190636660
312 312 a, c dbSNP:537704842
326 326 c, t dbSNP:775038732
384 384 a, g dbSNP:539228710
407 407 c, t dbSNP:570374465
416 416 a, g dbSNP:556123929
418 418 c, g dbSNP:185724844
433 433 c, t dbSNP:536860021
449 449 c, g dbSNP:369730594
484 484 a, c dbSNP:763740136
505 505 c, g dbSNP:547452704
558 558 a, g dbSNP:532147840
560 560 c, t dbSNP:147311377
582 582 g, t dbSNP:76656357
596 596 a, g dbSNP:771615660
599 599 a, g dbSNP:745452982
600 600 a, g dbSNP:769439691
617 617 c, t dbSNP:770818959
621 621 a, g dbSNP:376944501
622 622 a, g dbSNP:549512721
626 626 c, g dbSNP:191210486
632 632 c, t dbSNP:748125094
634 634 g, t dbSNP:779944223
653 653 a, c dbSNP:780865517
673 673 a, c, t dbSNP:8192466
687 687 a, g dbSNP:779925777
707 707 c, t dbSNP:758200229
717 717 a, g dbSNP:750397219
738 738 a, g dbSNP:764254110
743 743 c, t dbSNP:760902255
747 747 c, t dbSNP:267602837
760 760 a, g, t dbSNP:767681787
777 777 a, g dbSNP:759834365
779 779 a, g dbSNP:374752426
780 780 c, t dbSNP:771341699
781 781 a, g dbSNP:763357890
789 789 c, g dbSNP:773773442
801 801 a, c dbSNP:769259549
803 803 c, t dbSNP:747701929
804 804 a, g dbSNP:146354977
812 812 a, g dbSNP:768158526
819 819 a, g dbSNP:746682028
824 824 c, t dbSNP:748122661
831 831 a, g dbSNP:779658522
838 838 c, t dbSNP:758274361
842 842 a, g dbSNP:529491621
857 857 c, t dbSNP:745797571
858 858 a, g dbSNP:779034534
863 863 c, t dbSNP:756240390
864 864 a, g dbSNP:6265
867 867 a, c dbSNP:767638736
877 877 a, t dbSNP:755097391
884 884 g, t dbSNP:201926642
889 889 a, g dbSNP:766646640
891 891 c, g dbSNP:139352447
893 893 g, t dbSNP:1048218
894 894 a, g dbSNP:372937141
901 901 a, g dbSNP:199638553
907 907 a, g dbSNP:370382246
918 918 a, g dbSNP:753561183
923 923 a, g dbSNP:776056344
926 926 c, t dbSNP:78675155
927 927 c, g dbSNP:746631679
932 932 c, t dbSNP:775282010
940 940 a, c, t dbSNP:745707481
941 941 a, g dbSNP:150767807
959 959 c, t dbSNP:757194182
961 961 a, g dbSNP:141477239
989 989 c, g dbSNP:148736382
991 991 a, t dbSNP:755151584
999 999 a, g dbSNP:751698045
1007 1007 c, t dbSNP:766669848
1020 1020 c, g dbSNP:758638310
1022 1022 c, t dbSNP:17852698
1026 1026 a, g dbSNP:766339291
1031 1031 c, t dbSNP:750743108
1033 1033 c, t dbSNP:765594245
1038 1038 a, c, t dbSNP:201119590
1042 1042 a, c dbSNP:1048220
1043 1043 a, g dbSNP:763510956
1048 1048 g, t dbSNP:1048221
1080 1080 a, c dbSNP:540912088
1085 1085 c, t dbSNP:760274076
1086 1086 a, g dbSNP:774985498
1091 1091 c, t dbSNP:771802172
1115 1115 a, g dbSNP:144235869
1117 1117 c, t dbSNP:774229943
1118 1118 a, g dbSNP:2353512
1121 1121 a, g dbSNP:749232626
1124 1124 c, t dbSNP:777804423
1131 1131 a, t dbSNP:201468555
1133 1133 g, t dbSNP:747058681
1147 1147 c, t dbSNP:750030464
1148 1148 a, g, t dbSNP:370102323
1151 1151 a, c, t dbSNP:376008850
1156 1156 c, t dbSNP:754270781
1157 1157 a, g dbSNP:764711746
1163 1163 a, t dbSNP:761108714
1176 1176 a, g, t dbSNP:77787410
1199 1199 a, g dbSNP:759249009
1202 1202 a, g dbSNP:774212958
1214 1214 c, t dbSNP:74975314
1228 1228 a, g dbSNP:762853361
1233 1233 a, c dbSNP:772901888
1237 1237 g, t dbSNP:769727156
1247 1247 a, g dbSNP:748036027
1261 1261 a, g dbSNP:780128716
1262 1262 a, c dbSNP:772201255
1277 1277 c, t dbSNP:746089117
1283 1283 c, t dbSNP:574936175
1294 1294 a, g dbSNP:757598331
1298 1298 c, t dbSNP:776524056
1301 1301 c, t dbSNP:778031646
1307 1307 a, g dbSNP:78572035
1310 1310 c, t dbSNP:138287649
1314 1314 a, c dbSNP:767130961
1320 1320 c, t dbSNP:759156741
1322 1322 g, t dbSNP:751233672
1326 1326 a, g dbSNP:766077652
1331 1331 c, t dbSNP:767047030
1332 1332 a, g dbSNP:762541432
1353 1353 a, c dbSNP:772989712
1359 1359 a, g dbSNP:764951525
1368 1368 a, g dbSNP:761800998
1388 1388 a, g dbSNP:776620062
1395 1395 a, g, t dbSNP:745999049
1413 1413 c, t dbSNP:761281403
1424 1424 c, t dbSNP:774437578
1426 1426 c, t dbSNP:771145439
1435 1435 -, gatta dbSNP:780624690
1435 1435 a, c, g dbSNP:778185724
1436 1436 a, g dbSNP:756500989
1437 1437 c, t dbSNP:748656340
1439 1439 -, atatt dbSNP:756542824
1443 1443 a, t dbSNP:781776605
1448 1448 -, caaaaatt dbSNP:767892799
1452 1452 -, aa dbSNP:751007747
1458 1458 -, ctat dbSNP:757951775
1461 1461 a, t dbSNP:541750774
1507 1507 -, t dbSNP:769564673
1527 1527 a, g dbSNP:574414545
1538