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ATXN7 cDNA ORF clone, Homo sapiens (human)

Gene Symbol ATXN7
Entrez Gene ID 6314
Full Name ataxin 7
Synonyms ADCAII, OPCA3, SCA7
General protein information
Preferred Names
ataxin-7
Names
ataxin-7
spinocerebellar ataxia type 7 protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

3

3p21.1-p12

Summary The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the 'pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. This locus has been mapped to chromosome 3, and it has been determined that the diseased allele associated with spinocerebellar ataxia-7 contains 38-130 CAG repeats (near the N-terminus), compared to 7-17 in the normal allele. The encoded protein is a component of the SPT3/TAF9/GCN5 acetyltransferase (STAGA) and TBP-free TAF-containing (TFTC) chromatin remodeling complexes, and it thus plays a role in transcriptional regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]. lac of sum
Disorder MIM:

607640

Disorder Html: Spinocerebellar ataxia-7, 164500 (3)

mRNA and Protein(s)

mRNA Protein Name
NM_001128149 NP_001121621 ataxin-7 isoform c
NM_001177387 NP_001170858 ataxin-7 isoform b
NM_000333 NP_000324 ataxin-7 isoform a



Homo sapiens (human) ATXN7 NP_001170858.1
Pan troglodytes (chimpanzee) ATXN7 XP_001174619.2
Canis lupus familiaris (dog) ATXN7 XP_005632413.1
Bos taurus (cattle) ATXN7 XP_002697032.2
Mus musculus (house mouse) Atxn7 NP_631973.3
Rattus norvegicus (Norway rat) Atxn7 XP_006251790.1
Gallus gallus (chicken) ATXN7 XP_004944715.1
Danio rerio (zebrafish) LOC100001490 XP_001341475.5
Xenopus (Silurana) tropicalis (western clawed frog) atxn7 NP_001106501.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ATXN7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ATXN7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu20360 NM_001128149 Homo sapiens ataxin 7 (ATXN7), transcript variant SCA7c, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $531.30
$759.00
OHu21671 NM_001177387 Homo sapiens ataxin 7 (ATXN7), transcript variant SCA7b, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $475.30
$679.00
OHu26052 NM_000333 Homo sapiens ataxin 7 (ATXN7), transcript variant SCA7a, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $475.30
$679.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu20360
Clone ID Related Accession (Same CDS sequence) NM_001128149
Accession Version NM_001128149.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2244bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product ataxin-7 isoform c
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP220889.1, AC012557.23, AK304062.1 and BI494079.1. On Apr 7, 2010 this sequence version replaced gi:189491741. Transcript Variant: This variant (SCA7c) differs in the 5' UTR and 5' coding region, and uses an alternate start codon, compared to variant SCA7a. The encoded isoform (c) has a distinct N-terminus and is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK304062.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGGAAGGTA GCAAGACGCC TCTCCAAAGC AGCCCTTCTG CGCAGGAGCT GAAAGCTCCA 
CTGGAAAGAA GACATAGCTC ATCCAGCAAG CCGCCTTTGG CCGTTCCTCC CACTTCAGTA
TTTTCCTTCT TCCCTTCTCT GTCCAAAAGC AAAGGAGGCA GTGCAAGTGG AAGCAACCGT
TCTTCCAGTG GAGGTGTTCT TAGCGCATCC TCATCAAGTT CCAAGTTGTT GAAATCACCC
AAAGAGAAAC TGCAGCTCAG GGGGAACACC AGGCCAATGC ATCCCATTCA GCAAAGTAGA
GTTCCCCATG GTAGAATCAT GACACCCTCT GTGAAAGTGG AAAAGATTCA TCCGAAAATG
GATGGCACAC TACTGAAATC TGCGGTGGGG CCAACCTGTC CTGCTACTGT GAGTTCCTTA
GTCAAGCCTG GCCTTAACTG CCCCTCAATA CCAAAGCCAA CCTTGCCTTC ACCTGGACAG
ATTCTGAATG GCAAAGGGCT TCCTGCACCG CCCACTCTGG AAAAGAAACC TGAAGACAAT
TCCAATAATA GGAAATTTTT AAATAAGAGA TTATCAGAAA GAGAGTTTGA TCCTGACATC
CACTGTGGGG TTATTGATCT CGACACCAAG AAGCCCTGCA CCCGGTCTTT GACATGCAAG
ACACATTCCT TAACCCAGCG CAGGGCTGTC CAGGGTAGAA GAAAACGATT TGATGTGTTA
TTAGCCGAGC ACAAAAACAA AACCAGGGAA AAGGAATTGA TTCGCCATCC GGACTCTCAG
CAACCACCGC AGCCTCTCAG GGACCCGCAT CCCGCCCCTC CTAGAACGTC ACAGGAGCCG
CACCAAAACC CTCACGGAGT GATTCCTTCC GAATCAAAGC CTTTTGTAGC TAGTAAACCT
AAACCTCACA CCCCCAGTCT TCCAAGGCCT CCAGGCTGCC CTGCTCAGCA AGGTGGGAGT
GCCCCCATTG ACCCTCCTCC AGTCCATGAA TCTCCACACC CTCCCCTGCC TGCCACTGAG
CCAGCTTCTC GGTTATCCAG TGAGGAGGGC GAAGGCGATG ACAAAGAAGA GTCTGTTGAA
AAACTGGACT GTCATTATTC AGGTCATCAT CCTCAGCCAG CATCTTTTTG CACATTTGGG
AGCCGGCAGA TAGGAAGAGG CTATTACGTG TTTGACTCCA GGTGGAATCG ACTTCGCTGC
GCCCTCAACC TCATGGTGGA GAAGCATCTG AATGCACAGC TATGGAAGAA AATCCCACCA
GTGCCCAGTA CCACCTCACC CATCTCCACA CGTATTCCTC ACCGGACAAA CTCTGTGCCG
ACATCACAAT GTGGAGTCAG CTATCTGGCA GCAGCCACCG TCTCTACATC CCCAGTCCTG
CTCTCATCTA CCTGCATCTC CCCAAATAGC AAATCGGTAC CAGCTCATGG AACCACACTA
AATGCACAGC CTGCTGCTTC AGGGGCGATG GATCCTGTGT GCAGTATGCA ATCCAGACAA
GTGTCCTCTT CATCCTCATC CCCTTCCACG CCCTCTGGCC TTTCCTCGGT TCCTTCCTCC
CCCATGTCCA GGAAACCTCA GAAATTGAAA TCCAGCAAAT CTTTGAGGCC CAAGGAGTCT
TCTGGTAACA GCACTAACTG TCAAAATGCC AGTAGCAGTA CCAGTGGCGG CTCAGGAAAG
AAACGCAAAA ACAGTTCCCC ACTGTTGGTT CACTCTTCCT CCTCCTCTTC CTCCTCCTCC
TCTTCTTCTC ATTCCATGGA GTCTTTTAGG AAAAACTGTG TGGCTCACTC TGGGCCTCCC
TACCCCTCAA CGGTAACATC TTCCCATAGC ATCGGCCTCA ACTGTGTGAC GAATAAAGCA
AATGCGGTGA ACGTCCGGCA TGACCAGTCA GGGAGGGGCC CCCCCACCGG GAGCCCTGCT
GAATCCATCA AGAGGATGAG TGTGATGGTG AACAGCAGTG ATTCTACTCT TTCTCTTGGG
CCATTCATTC ACCAGTCCAA TGAACTGCCT GTCAACTCCC ACGGCAGTTT TTCCCACTCA
CACACTCCTC TAGACAAACT CATAGGAAAG AAAAGAAAGT GCTCACCCAG CTCGAGCAGC
ATCAACAACA GCAGCAGCAA ACCCACAAAG GTTGCCAAAG TGCCAGCCGT GAACAATGTC
CACATGAAAC ACACAGGCAC CATCCCAGGG GCACAAGGAC TGATGAACAG TTCCCTCCTT
CATCAGCCAA AGGCACGTCC CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001121621.2
CDS169..2412
Misc Feature(1)166..168(+)
Misc Feature(2)682..924(+)
Exon (1)1..232
Gene:ATXN7
Gene Synonym:
Exon (2)233..485
Gene:ATXN7
Gene Synonym:
Exon (3)486..745
Gene:ATXN7
Gene Synonym:
Exon (4)746..828
Gene:ATXN7
Gene Synonym:
Exon (5)829..1094
Gene:ATXN7
Gene Synonym:
Exon (6)1095..1293
Gene:ATXN7
Gene Synonym:
Exon (7)1294..1415
Gene:ATXN7
Gene Synonym:
Exon (8)1416..2394
Gene:ATXN7
Gene Synonym:
Exon (9)2395..6407
Gene:ATXN7
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001128149
Organism Homo sapiens (human)
Definition Homo sapiens ataxin 7 (ATXN7), transcript variant SCA7c, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001128149

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
ATGGAAGGTA GCAAGACGCC TCTCCAAAGC AGCCCTTCTG CGCAGGAGCT GAAAGCTCCA 
CTGGAAAGAA GACATAGCTC ATCCAGCAAG CCGCCTTTGG CCGTTCCTCC CACTTCAGTA
TTTTCCTTCT TCCCTTCTCT GTCCAAAAGC AAAGGAGGCA GTGCAAGTGG AAGCAACCGT
TCTTCCAGTG GAGGTGTTCT TAGCGCATCC TCATCAAGTT CCAAGTTGTT GAAATCACCC
AAAGAGAAAC TGCAGCTCAG GGGGAACACC AGGCCAATGC ATCCCATTCA GCAAAGTAGA
GTTCCCCATG GTAGAATCAT GACACCCTCT GTGAAAGTGG AAAAGATTCA TCCGAAAATG
GATGGCACAC TACTGAAATC TGCGGTGGGG CCAACCTGTC CTGCTACTGT GAGTTCCTTA
GTCAAGCCTG GCCTTAACTG CCCCTCAATA CCAAAGCCAA CCTTGCCTTC ACCTGGACAG
ATTCTGAATG GCAAAGGGCT TCCTGCACCG CCCACTCTGG AAAAGAAACC TGAAGACAAT
TCCAATAATA GGAAATTTTT AAATAAGAGA TTATCAGAAA GAGAGTTTGA TCCTGACATC
CACTGTGGGG TTATTGATCT CGACACCAAG AAGCCCTGCA CCCGGTCTTT GACATGCAAG
ACACATTCCT TAACCCAGCG CAGGGCTGTC CAGGGTAGAA GAAAACGATT TGATGTGTTA
TTAGCCGAGC ACAAAAACAA AACCAGGGAA AAGGAATTGA TTCGCCATCC GGACTCTCAG
CAACCACCGC AGCCTCTCAG GGACCCGCAT CCCGCCCCTC CTAGAACGTC ACAGGAGCCG
CACCAAAACC CTCACGGAGT GATTCCTTCC GAATCAAAGC CTTTTGTAGC TAGTAAACCT
AAACCTCACA CCCCCAGTCT TCCAAGGCCT CCAGGCTGCC CTGCTCAGCA AGGTGGGAGT
GCCCCCATTG ACCCTCCTCC AGTCCATGAA TCTCCACACC CTCCCCTGCC TGCCACTGAG
CCAGCTTCTC GGTTATCCAG TGAGGAGGGC GAAGGCGATG ACAAAGAAGA GTCTGTTGAA
AAACTGGACT GTCATTATTC AGGTCATCAT CCTCAGCCAG CATCTTTTTG CACATTTGGG
AGCCGGCAGA TAGGAAGAGG CTATTACGTG TTTGACTCCA GGTGGAATCG ACTTCGCTGC
GCCCTCAACC TCATGGTGGA GAAGCATCTG AATGCACAGC TATGGAAGAA AATCCCACCA
GTGCCCAGTA CCACCTCACC CATCTCCACA CGTATTCCTC ACCGGACAAA CTCTGTGCCG
ACATCACAAT GTGGAGTCAG CTATCTGGCA GCAGCCACCG TCTCTACATC CCCAGTCCTG
CTCTCATCTA CCTGCATCTC CCCAAATAGC AAATCGGTAC CAGCTCATGG AACCACACTA
AATGCACAGC CTGCTGCTTC AGGGGCGATG GATCCTGTGT GCAGTATGCA ATCCAGACAA
GTGTCCTCTT CATCCTCATC CCCTTCCACG CCCTCTGGCC TTTCCTCGGT TCCTTCCTCC
CCCATGTCCA GGAAACCTCA GAAATTGAAA TCCAGCAAAT CTTTGAGGCC CAAGGAGTCT
TCTGGTAACA GCACTAACTG TCAAAATGCC AGTAGCAGTA CCAGTGGCGG CTCAGGAAAG
AAACGCAAAA ACAGTTCCCC ACTGTTGGTT CACTCTTCCT CCTCCTCTTC CTCCTCCTCC
TCTTCTTCTC ATTCCATGGA GTCTTTTAGG AAAAACTGTG TGGCTCACTC TGGGCCTCCC
TACCCCTCAA CGGTAACATC TTCCCATAGC ATCGGCCTCA ACTGTGTGAC GAATAAAGCA
AATGCGGTGA ACGTCCGGCA TGACCAGTCA GGGAGGGGCC CCCCCACCGG GAGCCCTGCT
GAATCCATCA AGAGGATGAG TGTGATGGTG AACAGCAGTG ATTCTACTCT TTCTCTTGGG
CCATTCATTC ACCAGTCCAA TGAACTGCCT GTCAACTCCC ACGGCAGTTT TTCCCACTCA
CACACTCCTC TAGACAAACT CATAGGAAAG AAAAGAAAGT GCTCACCCAG CTCGAGCAGC
ATCAACAACA GCAGCAGCAA ACCCACAAAG GTTGCCAAAG TGCCAGCCGT GAACAATGTC
CACATGAAAC ACACAGGCAC CATCCCAGGG GCACAAGGAC TGATGAACAG TTCCCTCCTT
CATCAGCCAA AGGCACGTCC CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu21671
Clone ID Related Accession (Same CDS sequence) NM_001177387
Accession Version NM_001177387.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2838bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product ataxin-7 isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ000517.1, AA398030.1, AC012557.23 and BI494079.1. Transcript Variant: This variant (SCA7b) includes an alternate exon that causes a frameshift in the 3' coding region, compared to variant SCA7a, resulting in an isoform (b) with a distinct and longer C-terminus, compared to isoform a. The 5' UTR is incomplete in this variant due to the presence of alternate splicing choices further upstream. There are no publicly available full-length transcripts representing this variant; it is represented based on data in PMID:12533095. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGTCGGAGC GGGCCGCGGA TGACGTCAGG GGGGAGCCGC GCCGCGCGGC GGCGGCGGCG 
GGCGGAGCAG CGGCCGCGGC CGCCCGGCAG CAGCAGCAGC AGCAGCAGCA GCAGCAGCCG
CCGCCTCCGC AGCCCCAGCG GCAGCAGCAC CCGCCACCGC CGCCACGGCG CACACGGCCG
GAGGACGGCG GGCCCGGCGC CGCCTCCACC TCGGCCGCCG CAATGGCGAC GGTCGGGGAG
CGCAGGCCTC TGCCCAGTCC TGAAGTGATG CTGGGACAGT CGTGGAATCT GTGGGTTGAG
GCTTCCAAAC TTCCTGGGAA GGACGGGACA GAATTGGACG AAAGTTTCAA GGAGTTTGGG
AAAAACCGCG AAGTCATGGG GCTCTGTCGG GAAGACATGC CAATATTTGG TTTCTGTCCA
GCCCATGATG ATTTCTACTT GGTGGTGTGT AACGACTGTA ATCAGGTTGT CAAACCGCAG
GCATTTCAAT CACATTATGA AAGAAGACAT AGCTCATCCA GCAAGCCGCC TTTGGCCGTT
CCTCCCACTT CAGTATTTTC CTTCTTCCCT TCTCTGTCCA AAAGCAAAGG AGGCAGTGCA
AGTGGAAGCA ACCGTTCTTC CAGTGGAGGT GTTCTTAGCG CATCCTCATC AAGTTCCAAG
TTGTTGAAAT CACCCAAAGA GAAACTGCAG CTCAGGGGGA ACACCAGGCC AATGCATCCC
ATTCAGCAAA GTAGAGTTCC CCATGGTAGA ATCATGACAC CCTCTGTGAA AGTGGAAAAG
ATTCATCCGA AAATGGATGG CACACTACTG AAATCTGCGG TGGGGCCAAC CTGTCCTGCT
ACTGTGAGTT CCTTAGTCAA GCCTGGCCTT AACTGCCCCT CAATACCAAA GCCAACCTTG
CCTTCACCTG GACAGATTCT GAATGGCAAA GGGCTTCCTG CACCGCCCAC TCTGGAAAAG
AAACCTGAAG ACAATTCCAA TAATAGGAAA TTTTTAAATA AGAGATTATC AGAAAGAGAG
TTTGATCCTG ACATCCACTG TGGGGTTATT GATCTCGACA CCAAGAAGCC CTGCACCCGG
TCTTTGACAT GCAAGACACA TTCCTTAACC CAGCGCAGGG CTGTCCAGGG TAGAAGAAAA
CGATTTGATG TGTTATTAGC CGAGCACAAA AACAAAACCA GGGAAAAGGA ATTGATTCGC
CATCCGGACT CTCAGCAACC ACCGCAGCCT CTCAGGGACC CGCATCCCGC CCCTCCTAGA
ACGTCACAGG AGCCGCACCA AAACCCTCAC GGAGTGATTC CTTCCGAATC AAAGCCTTTT
GTAGCTAGTA AACCTAAACC TCACACCCCC AGTCTTCCAA GGCCTCCAGG CTGCCCTGCT
CAGCAAGGTG GGAGTGCCCC CATTGACCCT CCTCCAGTCC ATGAATCTCC ACACCCTCCC
CTGCCTGCCA CTGAGCCAGC TTCTCGGTTA TCCAGTGAGG AGGGCGAAGG CGATGACAAA
GAAGAGTCTG TTGAAAAACT GGACTGTCAT TATTCAGGTC ATCATCCTCA GCCAGCATCT
TTTTGCACAT TTGGGAGCCG GCAGATAGGA AGAGGCTATT ACGTGTTTGA CTCCAGGTGG
AATCGACTTC GCTGCGCCCT CAACCTCATG GTGGAGAAGC ATCTGAATGC ACAGCTATGG
AAGAAAATCC CACCAGTGCC CAGTACCACC TCACCCATCT CCACACGTAT TCCTCACCGG
ACAAACTCTG TGCCGACATC ACAATGTGGA GTCAGCTATC TGGCAGCAGC CACCGTCTCT
ACATCCCCAG TCCTGCTCTC ATCTACCTGC ATCTCCCCAA ATAGCAAATC GGTACCAGCT
CATGGAACCA CACTAAATGC ACAGCCTGCT GCTTCAGGGG CGATGGATCC TGTGTGCAGT
ATGCAATCCA GACAAGTGTC CTCTTCATCC TCATCCCCTT CCACGCCCTC TGGCCTTTCC
TCGGTTCCTT CCTCCCCCAT GTCCAGGAAA CCTCAGAAAT TGAAATCCAG CAAATCTTTG
AGGCCCAAGG AGTCTTCTGG TAACAGCACT AACTGTCAAA ATGCCAGTAG CAGTACCAGT
GGCGGCTCAG GAAAGAAACG CAAAAACAGT TCCCCACTGT TGGTTCACTC TTCCTCCTCC
TCTTCCTCCT CCTCCTCTTC TTCTCATTCC ATGGAGTCTT TTAGGAAAAA CTGTGTGGCT
CACTCTGGGC CTCCCTACCC CTCAACGGTA ACATCTTCCC ATAGCATCGG CCTCAACTGT
GTGACGAATA AAGCAAATGC GGTGAACGTC CGGCATGACC AGTCAGGGAG GGGCCCCCCC
ACCGGGAGCC CTGCTGAATC CATCAAGAGG ATGAGTGTGA TGGTGAACAG CAGTGATTCT
ACTCTTTCTC TTGGGCCATT CATTCACCAG TCCAATGAAC TGCCTGTCAA CTCCCACGGC
AGTTTTTCCC ACTCACACAC TCCTCTAGAC AAACTCATAG GAAAGAAAAG AAAGTGCTCA
CCCAGCTCGA GCAGCATCAA CAACAGCAGC AGCAAACCCA CAAAGGTTGC CAAAGTGCCA
GCCGTGAACA ATGTCCACAT GAAACACACA GGCACCATCC CAGGGGCACA AGGACTGATG
AACAGTTCCC TCCTTCATCA GGATATCTCC TCACCTTGCT TACGAACAGG AATTTCAGCA
ACATCACCCC AGAGCCCTGA CTTAAAATCC AAAGGCACGT CCCTGACAGC TGAAAATAGC
ACGGGGAGGA ATAATGCGGA CACTTTTGAG GACAAGTTAC ACCTCCACTC AGCACTCTGG
ACTCCACGAT GCCTTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001170858.1
CDS111..2948
Misc Feature(1)60..62(+)
Misc Feature(2)1059..1301(+)
Exon (1)1..99
Gene:ATXN7
Gene Synonym:
Exon (2)100..435
Gene:ATXN7
Gene Synonym:
Exon (3)436..504
Gene:ATXN7
Gene Synonym:
Exon (4)505..609
Gene:ATXN7
Gene Synonym:
Exon (5)610..862
Gene:ATXN7
Gene Synonym:
Exon (6)863..1122
Gene:ATXN7
Gene Synonym:
Exon (7)1123..1205
Gene:ATXN7
Gene Synonym:
Exon (8)1206..1471
Gene:ATXN7
Gene Synonym:
Exon (9)1472..1670
Gene:ATXN7
Gene Synonym:
Exon (10)1671..1792
Gene:ATXN7
Gene Synonym:
Exon (11)1793..2771
Gene:ATXN7
Gene Synonym:
Exon (12)2772..2838
Gene:ATXN7
Gene Synonym:
Exon (13)2839..6851
Gene:ATXN7
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001177387
Organism Homo sapiens (human)
Definition Homo sapiens ataxin 7 (ATXN7), transcript variant SCA7b, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001177387

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGTCGGAGC GGGCCGCGGA TGACGTCAGG GGGGAGCCGC GCCGCGCGGC GGCGGCGGCG 
GGCGGAGCAG CGGCCGCGGC CGCCCGGCAG CAGCAGCAGC AGCAGCAGCA GCAGCAGCCG
CCGCCTCCGC AGCCCCAGCG GCAGCAGCAC CCGCCACCGC CGCCACGGCG CACACGGCCG
GAGGACGGCG GGCCCGGCGC CGCCTCCACC TCGGCCGCCG CAATGGCGAC GGTCGGGGAG
CGCAGGCCTC TGCCCAGTCC TGAAGTGATG CTGGGACAGT CGTGGAATCT GTGGGTTGAG
GCTTCCAAAC TTCCTGGGAA GGACGGGACA GAATTGGACG AAAGTTTCAA GGAGTTTGGG
AAAAACCGCG AAGTCATGGG GCTCTGTCGG GAAGACATGC CAATATTTGG TTTCTGTCCA
GCCCATGATG ATTTCTACTT GGTGGTGTGT AACGACTGTA ATCAGGTTGT CAAACCGCAG
GCATTTCAAT CACATTATGA AAGAAGACAT AGCTCATCCA GCAAGCCGCC TTTGGCCGTT
CCTCCCACTT CAGTATTTTC CTTCTTCCCT TCTCTGTCCA AAAGCAAAGG AGGCAGTGCA
AGTGGAAGCA ACCGTTCTTC CAGTGGAGGT GTTCTTAGCG CATCCTCATC AAGTTCCAAG
TTGTTGAAAT CACCCAAAGA GAAACTGCAG CTCAGGGGGA ACACCAGGCC AATGCATCCC
ATTCAGCAAA GTAGAGTTCC CCATGGTAGA ATCATGACAC CCTCTGTGAA AGTGGAAAAG
ATTCATCCGA AAATGGATGG CACACTACTG AAATCTGCGG TGGGGCCAAC CTGTCCTGCT
ACTGTGAGTT CCTTAGTCAA GCCTGGCCTT AACTGCCCCT CAATACCAAA GCCAACCTTG
CCTTCACCTG GACAGATTCT GAATGGCAAA GGGCTTCCTG CACCGCCCAC TCTGGAAAAG
AAACCTGAAG ACAATTCCAA TAATAGGAAA TTTTTAAATA AGAGATTATC AGAAAGAGAG
TTTGATCCTG ACATCCACTG TGGGGTTATT GATCTCGACA CCAAGAAGCC CTGCACCCGG
TCTTTGACAT GCAAGACACA TTCCTTAACC CAGCGCAGGG CTGTCCAGGG TAGAAGAAAA
CGATTTGATG TGTTATTAGC CGAGCACAAA AACAAAACCA GGGAAAAGGA ATTGATTCGC
CATCCGGACT CTCAGCAACC ACCGCAGCCT CTCAGGGACC CGCATCCCGC CCCTCCTAGA
ACGTCACAGG AGCCGCACCA AAACCCTCAC GGAGTGATTC CTTCCGAATC AAAGCCTTTT
GTAGCTAGTA AACCTAAACC TCACACCCCC AGTCTTCCAA GGCCTCCAGG CTGCCCTGCT
CAGCAAGGTG GGAGTGCCCC CATTGACCCT CCTCCAGTCC ATGAATCTCC ACACCCTCCC
CTGCCTGCCA CTGAGCCAGC TTCTCGGTTA TCCAGTGAGG AGGGCGAAGG CGATGACAAA
GAAGAGTCTG TTGAAAAACT GGACTGTCAT TATTCAGGTC ATCATCCTCA GCCAGCATCT
TTTTGCACAT TTGGGAGCCG GCAGATAGGA AGAGGCTATT ACGTGTTTGA CTCCAGGTGG
AATCGACTTC GCTGCGCCCT CAACCTCATG GTGGAGAAGC ATCTGAATGC ACAGCTATGG
AAGAAAATCC CACCAGTGCC CAGTACCACC TCACCCATCT CCACACGTAT TCCTCACCGG
ACAAACTCTG TGCCGACATC ACAATGTGGA GTCAGCTATC TGGCAGCAGC CACCGTCTCT
ACATCCCCAG TCCTGCTCTC ATCTACCTGC ATCTCCCCAA ATAGCAAATC GGTACCAGCT
CATGGAACCA CACTAAATGC ACAGCCTGCT GCTTCAGGGG CGATGGATCC TGTGTGCAGT
ATGCAATCCA GACAAGTGTC CTCTTCATCC TCATCCCCTT CCACGCCCTC TGGCCTTTCC
TCGGTTCCTT CCTCCCCCAT GTCCAGGAAA CCTCAGAAAT TGAAATCCAG CAAATCTTTG
AGGCCCAAGG AGTCTTCTGG TAACAGCACT AACTGTCAAA ATGCCAGTAG CAGTACCAGT
GGCGGCTCAG GAAAGAAACG CAAAAACAGT TCCCCACTGT TGGTTCACTC TTCCTCCTCC
TCTTCCTCCT CCTCCTCTTC TTCTCATTCC ATGGAGTCTT TTAGGAAAAA CTGTGTGGCT
CACTCTGGGC CTCCCTACCC CTCAACGGTA ACATCTTCCC ATAGCATCGG CCTCAACTGT
GTGACGAATA AAGCAAATGC GGTGAACGTC CGGCATGACC AGTCAGGGAG GGGCCCCCCC
ACCGGGAGCC CTGCTGAATC CATCAAGAGG ATGAGTGTGA TGGTGAACAG CAGTGATTCT
ACTCTTTCTC TTGGGCCATT CATTCACCAG TCCAATGAAC TGCCTGTCAA CTCCCACGGC
AGTTTTTCCC ACTCACACAC TCCTCTAGAC AAACTCATAG GAAAGAAAAG AAAGTGCTCA
CCCAGCTCGA GCAGCATCAA CAACAGCAGC AGCAAACCCA CAAAGGTTGC CAAAGTGCCA
GCCGTGAACA ATGTCCACAT GAAACACACA GGCACCATCC CAGGGGCACA AGGACTGATG
AACAGTTCCC TCCTTCATCA GGATATCTCC TCACCTTGCT TACGAACAGG AATTTCAGCA
ACATCACCCC AGAGCCCTGA CTTAAAATCC AAAGGCACGT CCCTGACAGC TGAAAATAGC
ACGGGGAGGA ATAATGCGGA CACTTTTGAG GACAAGTTAC ACCTCCACTC AGCACTCTGG
ACTCCACGAT GCCTTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu26052
Clone ID Related Accession (Same CDS sequence) NM_000333
Accession Version NM_000333.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2679bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product ataxin-7 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF032104.1, AJ000517.1, AC012557.23 and BI494079.1. This sequence is a reference standard in the RefSeqGene project. On Jun 8, 2008 this sequence version replaced gi:51479163. Transcript Variant: This variant (SCA7a) represents the predominant transcript and encodes isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ000517.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
ATGTCGGAGC GGGCCGCGGA TGACGTCAGG GGGGAGCCGC GCCGCGCGGC GGCGGCGGCG 
GGCGGAGCAG CGGCCGCGGC CGCCCGGCAG CAGCAGCAGC AGCAGCAGCA GCAGCAGCCG
CCGCCTCCGC AGCCCCAGCG GCAGCAGCAC CCGCCACCGC CGCCACGGCG CACACGGCCG
GAGGACGGCG GGCCCGGCGC CGCCTCCACC TCGGCCGCCG CAATGGCGAC GGTCGGGGAG
CGCAGGCCTC TGCCCAGTCC TGAAGTGATG CTGGGACAGT CGTGGAATCT GTGGGTTGAG
GCTTCCAAAC TTCCTGGGAA GGACGGGACA GAATTGGACG AAAGTTTCAA GGAGTTTGGG
AAAAACCGCG AAGTCATGGG GCTCTGTCGG GAAGACATGC CAATATTTGG TTTCTGTCCA
GCCCATGATG ATTTCTACTT GGTGGTGTGT AACGACTGTA ATCAGGTTGT CAAACCGCAG
GCATTTCAAT CACATTATGA AAGAAGACAT AGCTCATCCA GCAAGCCGCC TTTGGCCGTT
CCTCCCACTT CAGTATTTTC CTTCTTCCCT TCTCTGTCCA AAAGCAAAGG AGGCAGTGCA
AGTGGAAGCA ACCGTTCTTC CAGTGGAGGT GTTCTTAGCG CATCCTCATC AAGTTCCAAG
TTGTTGAAAT CACCCAAAGA GAAACTGCAG CTCAGGGGGA ACACCAGGCC AATGCATCCC
ATTCAGCAAA GTAGAGTTCC CCATGGTAGA ATCATGACAC CCTCTGTGAA AGTGGAAAAG
ATTCATCCGA AAATGGATGG CACACTACTG AAATCTGCGG TGGGGCCAAC CTGTCCTGCT
ACTGTGAGTT CCTTAGTCAA GCCTGGCCTT AACTGCCCCT CAATACCAAA GCCAACCTTG
CCTTCACCTG GACAGATTCT GAATGGCAAA GGGCTTCCTG CACCGCCCAC TCTGGAAAAG
AAACCTGAAG ACAATTCCAA TAATAGGAAA TTTTTAAATA AGAGATTATC AGAAAGAGAG
TTTGATCCTG ACATCCACTG TGGGGTTATT GATCTCGACA CCAAGAAGCC CTGCACCCGG
TCTTTGACAT GCAAGACACA TTCCTTAACC CAGCGCAGGG CTGTCCAGGG TAGAAGAAAA
CGATTTGATG TGTTATTAGC CGAGCACAAA AACAAAACCA GGGAAAAGGA ATTGATTCGC
CATCCGGACT CTCAGCAACC ACCGCAGCCT CTCAGGGACC CGCATCCCGC CCCTCCTAGA
ACGTCACAGG AGCCGCACCA AAACCCTCAC GGAGTGATTC CTTCCGAATC AAAGCCTTTT
GTAGCTAGTA AACCTAAACC TCACACCCCC AGTCTTCCAA GGCCTCCAGG CTGCCCTGCT
CAGCAAGGTG GGAGTGCCCC CATTGACCCT CCTCCAGTCC ATGAATCTCC ACACCCTCCC
CTGCCTGCCA CTGAGCCAGC TTCTCGGTTA TCCAGTGAGG AGGGCGAAGG CGATGACAAA
GAAGAGTCTG TTGAAAAACT GGACTGTCAT TATTCAGGTC ATCATCCTCA GCCAGCATCT
TTTTGCACAT TTGGGAGCCG GCAGATAGGA AGAGGCTATT ACGTGTTTGA CTCCAGGTGG
AATCGACTTC GCTGCGCCCT CAACCTCATG GTGGAGAAGC ATCTGAATGC ACAGCTATGG
AAGAAAATCC CACCAGTGCC CAGTACCACC TCACCCATCT CCACACGTAT TCCTCACCGG
ACAAACTCTG TGCCGACATC ACAATGTGGA GTCAGCTATC TGGCAGCAGC CACCGTCTCT
ACATCCCCAG TCCTGCTCTC ATCTACCTGC ATCTCCCCAA ATAGCAAATC GGTACCAGCT
CATGGAACCA CACTAAATGC ACAGCCTGCT GCTTCAGGGG CGATGGATCC TGTGTGCAGT
ATGCAATCCA GACAAGTGTC CTCTTCATCC TCATCCCCTT CCACGCCCTC TGGCCTTTCC
TCGGTTCCTT CCTCCCCCAT GTCCAGGAAA CCTCAGAAAT TGAAATCCAG CAAATCTTTG
AGGCCCAAGG AGTCTTCTGG TAACAGCACT AACTGTCAAA ATGCCAGTAG CAGTACCAGT
GGCGGCTCAG GAAAGAAACG CAAAAACAGT TCCCCACTGT TGGTTCACTC TTCCTCCTCC
TCTTCCTCCT CCTCCTCTTC TTCTCATTCC ATGGAGTCTT TTAGGAAAAA CTGTGTGGCT
CACTCTGGGC CTCCCTACCC CTCAACGGTA ACATCTTCCC ATAGCATCGG CCTCAACTGT
GTGACGAATA AAGCAAATGC GGTGAACGTC CGGCATGACC AGTCAGGGAG GGGCCCCCCC
ACCGGGAGCC CTGCTGAATC CATCAAGAGG ATGAGTGTGA TGGTGAACAG CAGTGATTCT
ACTCTTTCTC TTGGGCCATT CATTCACCAG TCCAATGAAC TGCCTGTCAA CTCCCACGGC
AGTTTTTCCC ACTCACACAC TCCTCTAGAC AAACTCATAG GAAAGAAAAG AAAGTGCTCA
CCCAGCTCGA GCAGCATCAA CAACAGCAGC AGCAAACCCA CAAAGGTTGC CAAAGTGCCA
GCCGTGAACA ATGTCCACAT GAAACACACA GGCACCATCC CAGGGGCACA AGGACTGATG
AACAGTTCCC TCCTTCATCA GCCAAAGGCA CGTCCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000324.1
CDS554..3232
Misc Feature(1)503..505(+)
Misc Feature(2)641..670(+)
Misc Feature(3)1502..1744(+)
Misc Feature(4)3071..3073(+)
Misc Feature(5)3098..3100(+)
Misc Feature(6)3113..3115(+)
Exon (1)1..443
Gene:ATXN7
Gene Synonym:
Exon (2)444..542
Gene:ATXN7
Gene Synonym:
Exon (3)543..878
Gene:ATXN7
Gene Synonym:
Exon (4)879..947
Gene:ATXN7
Gene Synonym:
Exon (5)948..1052
Gene:ATXN7
Gene Synonym:
Exon (6)1053..1305
Gene:ATXN7
Gene Synonym:
Exon (7)1306..1565
Gene:ATXN7
Gene Synonym:
Exon (8)1566..1648
Gene:ATXN7
Gene Synonym:
Exon (9)1649..1914
Gene:ATXN7
Gene Synonym:
Exon (10)1915..2113
Gene:ATXN7
Gene Synonym:
Exon (11)2114..2235
Gene:ATXN7
Gene Synonym:
Exon (12)2236..3214
Gene:ATXN7
Gene Synonym:
Exon (13)3215..7227
Gene:ATXN7
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_000333
Organism Homo sapiens (human)
Definition Homo sapiens ataxin 7 (ATXN7), transcript variant SCA7a, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000333

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
ATGTCGGAGC GGGCCGCGGA TGACGTCAGG GGGGAGCCGC GCCGCGCGGC GGCGGCGGCG 
GGCGGAGCAG CGGCCGCGGC CGCCCGGCAG CAGCAGCAGC AGCAGCAGCA GCAGCAGCCG
CCGCCTCCGC AGCCCCAGCG GCAGCAGCAC CCGCCACCGC CGCCACGGCG CACACGGCCG
GAGGACGGCG GGCCCGGCGC CGCCTCCACC TCGGCCGCCG CAATGGCGAC GGTCGGGGAG
CGCAGGCCTC TGCCCAGTCC TGAAGTGATG CTGGGACAGT CGTGGAATCT GTGGGTTGAG
GCTTCCAAAC TTCCTGGGAA GGACGGGACA GAATTGGACG AAAGTTTCAA GGAGTTTGGG
AAAAACCGCG AAGTCATGGG GCTCTGTCGG GAAGACATGC CAATATTTGG TTTCTGTCCA
GCCCATGATG ATTTCTACTT GGTGGTGTGT AACGACTGTA ATCAGGTTGT CAAACCGCAG
GCATTTCAAT CACATTATGA AAGAAGACAT AGCTCATCCA GCAAGCCGCC TTTGGCCGTT
CCTCCCACTT CAGTATTTTC CTTCTTCCCT TCTCTGTCCA AAAGCAAAGG AGGCAGTGCA
AGTGGAAGCA ACCGTTCTTC CAGTGGAGGT GTTCTTAGCG CATCCTCATC AAGTTCCAAG
TTGTTGAAAT CACCCAAAGA GAAACTGCAG CTCAGGGGGA ACACCAGGCC AATGCATCCC
ATTCAGCAAA GTAGAGTTCC CCATGGTAGA ATCATGACAC CCTCTGTGAA AGTGGAAAAG
ATTCATCCGA AAATGGATGG CACACTACTG AAATCTGCGG TGGGGCCAAC CTGTCCTGCT
ACTGTGAGTT CCTTAGTCAA GCCTGGCCTT AACTGCCCCT CAATACCAAA GCCAACCTTG
CCTTCACCTG GACAGATTCT GAATGGCAAA GGGCTTCCTG CACCGCCCAC TCTGGAAAAG
AAACCTGAAG ACAATTCCAA TAATAGGAAA TTTTTAAATA AGAGATTATC AGAAAGAGAG
TTTGATCCTG ACATCCACTG TGGGGTTATT GATCTCGACA CCAAGAAGCC CTGCACCCGG
TCTTTGACAT GCAAGACACA TTCCTTAACC CAGCGCAGGG CTGTCCAGGG TAGAAGAAAA
CGATTTGATG TGTTATTAGC CGAGCACAAA AACAAAACCA GGGAAAAGGA ATTGATTCGC
CATCCGGACT CTCAGCAACC ACCGCAGCCT CTCAGGGACC CGCATCCCGC CCCTCCTAGA
ACGTCACAGG AGCCGCACCA AAACCCTCAC GGAGTGATTC CTTCCGAATC AAAGCCTTTT
GTAGCTAGTA AACCTAAACC TCACACCCCC AGTCTTCCAA GGCCTCCAGG CTGCCCTGCT
CAGCAAGGTG GGAGTGCCCC CATTGACCCT CCTCCAGTCC ATGAATCTCC ACACCCTCCC
CTGCCTGCCA CTGAGCCAGC TTCTCGGTTA TCCAGTGAGG AGGGCGAAGG CGATGACAAA
GAAGAGTCTG TTGAAAAACT GGACTGTCAT TATTCAGGTC ATCATCCTCA GCCAGCATCT
TTTTGCACAT TTGGGAGCCG GCAGATAGGA AGAGGCTATT ACGTGTTTGA CTCCAGGTGG
AATCGACTTC GCTGCGCCCT CAACCTCATG GTGGAGAAGC ATCTGAATGC ACAGCTATGG
AAGAAAATCC CACCAGTGCC CAGTACCACC TCACCCATCT CCACACGTAT TCCTCACCGG
ACAAACTCTG TGCCGACATC ACAATGTGGA GTCAGCTATC TGGCAGCAGC CACCGTCTCT
ACATCCCCAG TCCTGCTCTC ATCTACCTGC ATCTCCCCAA ATAGCAAATC GGTACCAGCT
CATGGAACCA CACTAAATGC ACAGCCTGCT GCTTCAGGGG CGATGGATCC TGTGTGCAGT
ATGCAATCCA GACAAGTGTC CTCTTCATCC TCATCCCCTT CCACGCCCTC TGGCCTTTCC
TCGGTTCCTT CCTCCCCCAT GTCCAGGAAA CCTCAGAAAT TGAAATCCAG CAAATCTTTG
AGGCCCAAGG AGTCTTCTGG TAACAGCACT AACTGTCAAA ATGCCAGTAG CAGTACCAGT
GGCGGCTCAG GAAAGAAACG CAAAAACAGT TCCCCACTGT TGGTTCACTC TTCCTCCTCC
TCTTCCTCCT CCTCCTCTTC TTCTCATTCC ATGGAGTCTT TTAGGAAAAA CTGTGTGGCT
CACTCTGGGC CTCCCTACCC CTCAACGGTA ACATCTTCCC ATAGCATCGG CCTCAACTGT
GTGACGAATA AAGCAAATGC GGTGAACGTC CGGCATGACC AGTCAGGGAG GGGCCCCCCC
ACCGGGAGCC CTGCTGAATC CATCAAGAGG ATGAGTGTGA TGGTGAACAG CAGTGATTCT
ACTCTTTCTC TTGGGCCATT CATTCACCAG TCCAATGAAC TGCCTGTCAA CTCCCACGGC
AGTTTTTCCC ACTCACACAC TCCTCTAGAC AAACTCATAG GAAAGAAAAG AAAGTGCTCA
CCCAGCTCGA GCAGCATCAA CAACAGCAGC AGCAAACCCA CAAAGGTTGC CAAAGTGCCA
GCCGTGAACA ATGTCCACAT GAAACACACA GGCACCATCC CAGGGGCACA AGGACTGATG
AACAGTTCCC TCCTTCATCA GCCAAAGGCA CGTCCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Origin of the spinocerebellar ataxia type 7 gene mutation in Mexican population
Cerebellum 12 (6), 902-905 (2013)
Magana JJ, Gomez R, Maldonado-Rodriguez M, Velazquez-Perez L, Tapia-Guerrero YS, Cortes H, Leyva-Garcia N, Hernandez-Hernandez O and Cisneros B.


book

Direct inhibition of Gcn5 protein catalytic activity by polyglutamine-expanded ataxin-7
J. Biol. Chem. 288 (47), 34266-34275 (2013)
Burke TL, Miller JL and Grant PA.


book

Structural basis for recognition of the third SH3 domain of full-length R85 (R85FL)/ponsin by ataxin-7
FEBS Lett. 587 (18), 2905-2911 (2013)
Jiang YJ, Zhou CJ, Zhou ZR, Wu M and Hu HY.


book

Reelin is a target of polyglutamine expanded ataxin-7 in human spinocerebellar ataxia type 7 (SCA7) astrocytes
Proc. Natl. Acad. Sci. U.S.A. 109 (52), 21319-21324 (2012)
McCullough SD, Xu X, Dent SY, Bekiranov S, Roeder RG and Grant PA.


book

A novel central nervous system-enriched spinocerebellar ataxia type 7 gene product
Arch. Neurol. 60 (1), 97-103 (2003)
Einum DD, Clark AM, Townsend JJ, Ptacek LJ and Fu YH.


book

Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion
Nat. Genet. 17 (1), 65-70 (1997)
David G, Abbas N, Stevanin G, Durr A, Yvert G, Cancel G, Weber C, Imbert G, Saudou F, Antoniou E, Drabkin H, Gemmill R, Giunti P, Benomar A, Wood N, Ruberg M, Agid Y, Mandel JL and Brice A.


book

The gene for autosomal dominant cerebellar ataxia with pigmentary macular dystrophy maps to chromosome 3p12-p21.1
Nat. Genet. 10 (1), 84-88 (1995)
Benomar A, Krols L, Stevanin G, Cancel G, LeGuern E, David G, Ouhabi H, Martin JJ, Durr A and Zaim A.


book

Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening
Genomics 23 (1), 42-50 (1994)
Robertson NG, Khetarpal U, Gutierrez-Espeleta GA, Bieber FR and Morton CC.


book

Spinocerebellar Ataxia Type 7
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Garden,G.


book

Hereditary Ataxia Overview
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Bird,T.D.


 
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