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SCNN1A sodium channel, non voltage gated 1 alpha subunit [Homo sapiens (human)]

Gene Symbol SCNN1A
Entrez Gene ID 6337
Full Name sodium channel, non voltage gated 1 alpha subunit
Synonyms BESC2, ENaCa, ENaCalpha, SCNEA, SCNN1
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12p13

Summary Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009]. lac of sum
Disorder MIM:

600228

Disorder Html: Pseudohypoaldosteronism, type I, 264350 (3); Bronchiectasis with





The following SCNN1A gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SCNN1A gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu19374 NM_001038 Homo sapiens sodium channel, non voltage gated 1 alpha subunit (SCNN1A), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$391.3
$559
OHu14485 NM_001159575 Homo sapiens sodium channel, non voltage gated 1 alpha subunit (SCNN1A), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD Quote Price
OHu14548 NM_001159576 Homo sapiens sodium channel, non voltage gated 1 alpha subunit (SCNN1A), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD Quote Price

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu19374
Accession Version NM_001038.5 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2010bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product amiloride-sensitive sodium channel subunit alpha isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB232484.1, X76180.1 and BU680600.1. This sequence is a reference standard in the RefSeqGene project. On Apr 23, 2009 this sequence version replaced gi:47834319. Summary: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009]. Transcript Variant: This variant (1, also known as alpha-ENaC1) represents the predominant transcript, and encodes isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X76180.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962346 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGGAGGGGA ACAAGCTGGA GGAGCAGGAC TCTAGCCCTC CACAGTCCAC TCCAGGGCTC 
ATGAAGGGGA ACAAGCGTGA GGAGCAGGGG CTGGGCCCCG AACCTGCGGC GCCCCAGCAG
CCCACGGCGG AGGAGGAGGC CCTGATCGAG TTCCACCGCT CCTACCGAGA GCTCTTCGAG
TTCTTCTGCA ACAACACCAC CATCCACGGC GCCATCCGCC TGGTGTGCTC CCAGCACAAC
CGCATGAAGA CGGCCTTCTG GGCAGTGCTG TGGCTCTGCA CCTTTGGCAT GATGTACTGG
CAATTCGGCC TGCTTTTCGG AGAGTACTTC AGCTACCCCG TCAGCCTCAA CATCAACCTC
AACTCGGACA AGCTCGTCTT CCCCGCAGTG ACCATCTGCA CCCTCAATCC CTACAGGTAC
CCGGAAATTA AAGAGGAGCT GGAGGAGCTG GACCGCATCA CAGAGCAGAC GCTCTTTGAC
CTGTACAAAT ACAGCTCCTT CACCACTCTC GTGGCCGGCT CCCGCAGCCG TCGCGACCTG
CGGGGGACTC TGCCGCACCC CTTGCAGCGC CTGAGGGTCC CGCCCCCGCC TCACGGGGCC
CGTCGAGCCC GTAGCGTGGC CTCCAGCTTG CGGGACAACA ACCCCCAGGT GGACTGGAAG
GACTGGAAGA TCGGCTTCCA GCTGTGCAAC CAGAACAAAT CGGACTGCTT CTACCAGACA
TACTCATCAG GGGTGGATGC GGTGAGGGAG TGGTACCGCT TCCACTACAT CAACATCCTG
TCGAGGCTGC CAGAGACTCT GCCATCCCTG GAGGAGGACA CGCTGGGCAA CTTCATCTTC
GCCTGCCGCT TCAACCAGGT CTCCTGCAAC CAGGCGAATT ACTCTCACTT CCACCACCCG
ATGTATGGAA ACTGCTATAC TTTCAATGAC AAGAACAACT CCAACCTCTG GATGTCTTCC
ATGCCTGGAA TCAACAACGG TCTGTCCCTG ATGCTGCGCG CAGAGCAGAA TGACTTCATT
CCCCTGCTGT CCACAGTGAC TGGGGCCCGG GTAATGGTGC ACGGGCAGGA TGAACCTGCC
TTTATGGATG ATGGTGGCTT TAACTTGCGG CCTGGCGTGG AGACCTCCAT CAGCATGAGG
AAGGAAACCC TGGACAGACT TGGGGGCGAT TATGGCGACT GCACCAAGAA TGGCAGTGAT
GTTCCTGTTG AGAACCTTTA CCCTTCAAAG TACACACAGC AGGTGTGTAT TCACTCCTGC
TTCCAGGAGA GCATGATCAA GGAGTGTGGC TGTGCCTACA TCTTCTATCC GCGGCCCCAG
AACGTGGAGT ACTGTGACTA CAGAAAGCAC AGTTCCTGGG GGTACTGCTA CTATAAGCTC
CAGGTTGACT TCTCCTCAGA CCACCTGGGC TGTTTCACCA AGTGCCGGAA GCCATGCAGC
GTGACCAGCT ACCAGCTCTC TGCTGGTTAC TCACGATGGC CCTCGGTGAC ATCCCAGGAA
TGGGTCTTCC AGATGCTATC GCGACAGAAC AATTACACCG TCAACAACAA GAGAAATGGA
GTGGCCAAAG TCAACATCTT CTTCAAGGAG CTGAACTACA AAACCAATTC TGAGTCTCCC
TCTGTCACGA TGGTCACCCT CCTGTCCAAC CTGGGCAGCC AGTGGAGCCT GTGGTTCGGC
TCCTCGGTGT TGTCTGTGGT GGAGATGGCT GAGCTCGTCT TTGACCTGCT GGTCATCATG
TTCCTCATGC TGCTCCGAAG GTTCCGAAGC CGATACTGGT CTCCAGGCCG AGGGGGCAGG
GGTGCTCAGG AGGTAGCCTC CACCCTGGCA TCCTCCCCTC CTTCCCACTT CTGCCCCCAC
CCCATGTCTC TGTCCTTGTC CCAGCCAGGC CCTGCTCCCT CTCCAGCCTT GACAGCCCCT
CCCCCTGCCT ATGCCACCCT GGGCCCCCGC CCATCTCCAG GGGGCTCTGC AGGGGCCAGT
TCCTCCACCT GTCCTCTGGG GGGGCCCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001029.1
CDS290..2299
Misc Feature(1)164..166(+)
Misc Feature(2)449..2230(+)
Misc Feature(3)473..2005(+)
Misc Feature(4)548..619(+)
Misc Feature(5)1919..2011(+)
Exon (1)1..235
Gene:SCNN1A
Gene Synonym:
Exon (2)236..705
Gene:SCNN1A
Gene Synonym:
Exon (3)706..973
Gene:SCNN1A
Gene Synonym:
Exon (4)974..1164
Gene:SCNN1A
Gene Synonym:
Exon (5)1165..1268
Gene:SCNN1A
Gene Synonym:
Exon (6)1269..1432
Gene:SCNN1A
Gene Synonym:
Exon (7)1433..1531
Gene:SCNN1A
Gene Synonym:
Exon (8)1532..1649
Gene:SCNN1A
Gene Synonym:
Exon (9)1650..1728
Gene:SCNN1A
Gene Synonym:
Exon (10)1729..1786
Gene:SCNN1A
Gene Synonym:
Exon (11)1787..1842
Gene:SCNN1A
Gene Synonym:
Exon (12)1843..1918
Gene:SCNN1A
Gene Synonym:
Exon (13)1919..3329
Gene:SCNN1A
Gene Synonym:
Translation
Position Chain Variation Link
12 12 g, t dbSNP:775221196
13 13 c, t dbSNP:372410235
14 14 a, g dbSNP:72645142
37 37 c, t dbSNP:72645141
38 38 a, g dbSNP:759031799
51 51 c, t dbSNP:142967664
65 65 c, t dbSNP:765963592
70 70 c, g dbSNP:148940975
78 78 a, g dbSNP:56130137
93 93 c, t dbSNP:72645140
94 94 a, g dbSNP:563337751
99 99 a, t dbSNP:553876167
104 104 c, t dbSNP:72645139
105 105 a, g dbSNP:777145578
124 124 c, t dbSNP:764749354
134 134 a, c, t dbSNP:72645138
135 135 a, g dbSNP:72645137
160 160 a, c dbSNP:569868085
163 163 a, g dbSNP:549775720
177 177 a, g dbSNP:72645136
178 178 c, t dbSNP:760323494
182 182 c, t dbSNP:529745550
187 187 c, t dbSNP:375596606
188 188 c, t dbSNP:775235238
193 193 a, g dbSNP:776185619
197 197 a, g dbSNP:10849447
198 198 c, g dbSNP:111613196
199 199 c, g, t dbSNP:112539501
204 204 a, g dbSNP:770758109
207 207 a, c dbSNP:749477197
221 221 c, t dbSNP:545108113
231 231 c, g dbSNP:72645135
242 242 a, g dbSNP:150809388
246 246 c, t dbSNP:776787803
262 262 c, t dbSNP:61759919
265 265 a, g dbSNP:369609706
267 267 c, g dbSNP:377074479
269 269 c, t dbSNP:556247628
272 272 a, c dbSNP:772741031
273 273 -, a dbSNP:772085907
285 285 c, g dbSNP:746190692
291 291 c, t dbSNP:779394345
292 292 a, g dbSNP:111550798
295 295 a, g dbSNP:757599210
297 297 a, g dbSNP:752387748
298 298 a, g dbSNP:780762241
313 313 a, g dbSNP:754452040
315 315 a, g dbSNP:142937915
317 317 a, g dbSNP:766263579
319 319 c, t dbSNP:762899862
322 322 -, t dbSNP:751119251
325 325 a, c dbSNP:372909867
346 346 a, g dbSNP:750401022
348 348 c, t dbSNP:765012846
351 351 c, t dbSNP:761572575
360 360 a, g dbSNP:148581573
363 363 a, g dbSNP:768767909
366 366 a, c, g, t dbSNP:72645127
380 380 a, c, t dbSNP:775062010
381 381 c, t dbSNP:771310951
382 382 a, g dbSNP:749626049
388 388 c, t dbSNP:13306619
389 389 a, g dbSNP:72645126
392 392 a, c dbSNP:746472088
394 394 c, t dbSNP:779509123
395 395 a, g dbSNP:757970565
396 396 c, t dbSNP:750349787
397 397 a, g dbSNP:765101499
399 399 c, t dbSNP:757014172
400 400 a, g dbSNP:571296830
413 413 a, g dbSNP:551220820
415 415 a, g dbSNP:138995556
416 416 a, g dbSNP:146187461
417 417 c, g, t dbSNP:759745474
418 418 a, g dbSNP:375919815
420 420 a, c dbSNP:771345288
422 422 c, g dbSNP:200068111
432 432 g, t dbSNP:185241340
436 436 a, c, t dbSNP:200770604
437 437 c, g dbSNP:779740460
446 446 c, t dbSNP:757847873
447 447 a, g dbSNP:201823143
455 455 c, t dbSNP:778872550
466 466 c, t dbSNP:560437072
472 472 a, c dbSNP:61758859
481 481 c, t dbSNP:757166697
483 483 a, c dbSNP:753866692
487 487 a, c dbSNP:374032839
492 492 -, tc dbSNP:765835593
496 496 c, t dbSNP:756036616
497 497 g, t dbSNP:370299321
498 498 c, g dbSNP:752951128
499 499 a, c, t dbSNP:368475363
500 500 a, g dbSNP:540601108
502 502 c, t dbSNP:374270705
505 505 c, t dbSNP:138613452
506 506 c, t dbSNP:763345732
511 511 a, g dbSNP:773836542
513 513 g, t dbSNP:770042605
519 519 c, t dbSNP:762180968
530 530 c, t dbSNP:61759860
534 534 g, t dbSNP:775058248
538 538 a, g dbSNP:371611492
541 541 a, g dbSNP:376913356
551 551 a, g dbSNP:778268845
561 561 g, t dbSNP:770518117
570 570 c, t dbSNP:749174523
574 574 c, t dbSNP:777820681
580 580 a, c, g dbSNP:752542101
587 587 c, g, t dbSNP:755271752
590 590 c, t dbSNP:751856853
595 595 c, t dbSNP:766337568
598 598 c, t dbSNP:763151595
601 601 c, g dbSNP:750838338
607 607 c, t dbSNP:148261445
608 608 a, g dbSNP:144763378
612 612 a, t dbSNP:777004900
618 618 c, t dbSNP:769061042
626 626 a, c, g dbSNP:774123732
628 628 c, t dbSNP:770329720
629 629 a, g dbSNP:61759861
635 635 c, t dbSNP:777501442
640 640 c, t dbSNP:769881891
645 645 a, g dbSNP:747901081
648 648 a, t dbSNP:575699161
652 652 a, c, t dbSNP:751718311
655 655 a, g dbSNP:373834849
658 658 c, g dbSNP:758345341
664 664 c, t dbSNP:750550104
666 666 -, t dbSNP:757895343
673 673 -, c dbSNP:754230610
673 673 c, t dbSNP:765686184
674 674 a, g, t dbSNP:141756749
678 678 c, t dbSNP:764441874
682 682 c, t dbSNP:761155056
688 688 c, t dbSNP:773813638
692 692 c, g dbSNP:766056130
697 697 c, t dbSNP:762326874
700 700 -, c dbSNP:764479792
705 705 a, g dbSNP:370256768
707 707 g, t dbSNP:564898684
724 724 a, g dbSNP:776644104
726 726 a, g dbSNP:768671376
733 733 -, ggagctgga dbSNP:760971071
741 741 a, g dbSNP:746734280
746 746 a, t dbSNP:775335440
755 755 c, g dbSNP:771805486
760 760 a, g dbSNP:746089331
767 767 a, g dbSNP:779168356
769 769 c, g dbSNP:757265424
770 770 a, c dbSNP:749370935
773 773 c, t dbSNP:201532601
777 777 a, c dbSNP:756664267
778 778 a, c dbSNP:753190765
779 779 c, t dbSNP:781587925
788 788 c, t dbSNP:755365105
813 813 a, g dbSNP:750086795
814 814 c, t dbSNP:764986095
829 829 g, t dbSNP:55859427
830 830 a, c, t dbSNP:55797039
832 832 a, g dbSNP:148904855
833 833 a, g dbSNP:775360187
835 835 -, g dbSNP:775723647
835 835 g, t dbSNP:771891536
844 844 a, g dbSNP:759343629
848 848 c, t dbSNP:774485921
852 852 a, t dbSNP:771170845
856 856 g, t dbSNP:199573198
857 857 c, t dbSNP:201246087
863 863 -, a dbSNP:767638989
864 864 c, g dbSNP:769803163
865 865 c, g dbSNP:574592585
868 868 a, c dbSNP:554754589
871 871 a, g dbSNP:755303181
876 876 c, t dbSNP:752004499
878 878 c, t dbSNP:778660547
883 883 c, t dbSNP:372705087
884 884 c, g dbSNP:753587879
887 887 -, g dbSNP:759611286
890 890 a, c, g, t dbSNP:752626882
897 897 c, t dbSNP:767356889
899 899 c, t dbSNP:759283975
903 903 a, g dbSNP:147866964
907 907 a, g dbSNP:770760088
908 908 g, t dbSNP:763129361
910 910 a, c dbSNP:773372073
914 914 a, c dbSNP:769902968
916 916 a, c dbSNP:748189603
918 918 g, t dbSNP:781695328
932 932 a, c, t dbSNP:747570345
937 937 a, g dbSNP:780536807
938 938 a, c, g dbSNP:200510319
941 941 a, g dbSNP:748960792
943 943 a, c dbSNP:767902038
948 948 a, g dbSNP:755588373
952 952 c, g dbSNP:748173628
958 958 c, g dbSNP:767436357
959 959 -, atc dbSNP:774475900
961 961 a, c dbSNP:754885393
967 967 a, c dbSNP:751536696
971 971 c, t dbSNP:766160514
984 984 a, g dbSNP:765128439
990 990 c, t dbSNP:761907917
991 991 a, g dbSNP:776977349
995 995 g, t dbSNP:764253958
1001 1001 c, t dbSNP:760847083
1016 1016 c, t dbSNP:776069930
1017 1017 c, t dbSNP:772732812
1029 1029 c, t dbSNP:746199428
1030 1030 a, g dbSNP:574585318
1035 1035 a, g dbSNP:142409152
1037 1037 g, t dbSNP:747753624
1043 1043 -, t dbSNP:769580746
1044 1044 a, g dbSNP:180729483
1046 1046 c, t dbSNP:771168777
1047 1047 a, g dbSNP:72645111
1053 1053 a, g dbSNP:551706206
1056 1056 a, g dbSNP:746527103
1058 1058 a, c dbSNP:779918209
1060 1060 c, t dbSNP:758245407
1067 1067 c, t dbSNP:750414125
1072 1072 a, g dbSNP:72645110
1077 1077 c, t dbSNP:757131301
1081 1081 a, g dbSNP:754052676
1086 1086 c, g dbSNP:781146561
1094 1094 c, t dbSNP:147702347
1095 1095 c, t dbSNP:72645109
1100 1100 a, g dbSNP:375898173
1103 1103 -, g dbSNP:747904876
1110 1110 c, t dbSNP:150033111
1111 1111 a, g dbSNP:372634287
1115 1115 g, t dbSNP:759933475
1127 1127 c, t dbSNP:774991447
1128 1128 c, t dbSNP:771188060
1129 1129 c, t dbSNP:139335335
1130 1130 a, c, g, t dbSNP:201553658
1131 1131 c, t dbSNP:779507200
1135 1135 a, c dbSNP:771678842
1136 1136 c, t dbSNP:745777993
1137 1137 a, g dbSNP:368942111
1138 1138 c, t dbSNP:770607083
1149 1149 c, t dbSNP:749335164
1153 1153 -, c dbSNP:780827736
1164 1164 a, c, t dbSNP:778088118
1174 1174 c, t dbSNP:754948204
1184 1184 c, t dbSNP:751693113
1186 1186 c, t dbSNP:766747041
1188 1188 c, t dbSNP:755217190
1192 1192 c, g dbSNP:750994375
1195 1195 c, t dbSNP:765571538
1200 1200 a, t dbSNP:762177076
1205 1205 a, t dbSNP:764914260
1206 1206 a, t dbSNP:774936628
1207 1207 c, t dbSNP:767227687
1224 1224 a, c dbSNP:758918630
1227 1227 a, g dbSNP:773885589
1241 1241 a, c dbSNP:770392706
1242 1242 g, t dbSNP:749237003
1265 1265 a, g dbSNP:773342959
1267 1267 c, t dbSNP:61731141
1275 1275 c, g dbSNP:779341775
1280 1280 a, t dbSNP:757735280
1286 1286 c, t dbSNP:146177203
1287 1287 a, g dbSNP:778199680
1288 1288 c, t dbSNP:756498521
1289 1289 a, g dbSNP:11542844
1294 1294 a, g dbSNP:766136849
1298 1298 a, g dbSNP:375310967
1299 1299 a, g dbSNP:749978185
1304 1304 g, t dbSNP:764889782
1312 1312 c, g dbSNP:371971622
1324 1324 a, g dbSNP:199671336
1325 1325 a, g dbSNP:768438286
1327 1327 g, t dbSNP:760389728
1336 1336 c, t dbSNP:775647330
1337 1337 c, g, t dbSNP:181065138
1338 1338 a, g, t dbSNP:534158738
1341 1341 c, t dbSNP:139861603
1345 1345 c, g dbSNP:778158546
1348 1348 g, t dbSNP:571599047
1350 1350 a, g dbSNP:753035419
1351 1351 c, t dbSNP:199947703
1352 1352 a, c, g dbSNP:189376498
1353 1353 c, g dbSNP:764826366
1355 1355 c, t dbSNP:761243273
1356 1356 a, g dbSNP:753740830
1362 1362 a, g dbSNP:569195112
1363 1363 a, g dbSNP:149430403
1364 1364 a, c, t dbSNP:767336946
1367 1367 a, g, t dbSNP:375159701
1368 1368 c, t dbSNP:770990050
1395 1395 g, t dbSNP:749335890
1396 1396 c, g dbSNP:369734906
1397 1397 c, t dbSNP:529383103
1398 1398 a, g dbSNP:372873824
1405 1405 c, t dbSNP:567003433
1406 1406 a, g dbSNP:368471914
1413 1413 c, t dbSNP:755461944
1418 1418 a, g dbSNP:193920773
1428 1428 a, g dbSNP:778711245
1437 1437 c, t dbSNP:777289941
1438 1438 a, c dbSNP:769075036
1443 1443 a, g dbSNP:201214012
1449 1449 c, t dbSNP:373986349
1456 1456 c, t dbSNP:756833708
1457 1457 a, g dbSNP:200557019
1462 1462 c, t dbSNP:777139886
1465 1465 c, t dbSNP:72657575
1472 1472 a, g dbSNP:201365745
1473 1473 c, g dbSNP:767449498
1474 1474 a, c, g dbSNP:202151383
1477 1477 a, g dbSNP:754732154
1479 1479 a, g dbSNP:751381592
1486 1486 a, t dbSNP:766246552
1489 1489 a, t dbSNP:763054871
1494 1494 a, c dbSNP:13306616
1504 1504 c, t dbSNP:765219923
1505 1505 a, c, t dbSNP:149484264
1511 1511 c, t dbSNP:769308083
1517 1517 a, g dbSNP:761309529
1529 1529 c, t dbSNP:138011635
1564 1564 g, t dbSNP:768222573
1578 1578 a, g dbSNP:200026546
1581 1581 a, g dbSNP:780056168
1587 1587 a, g dbSNP:758087809
1588 1588 c, t dbSNP:375712066
1589 1589 a, c dbSNP:778899717
1594 1594 -, c dbSNP:758014063
1596 1596 a, c dbSNP:372997123
1599 1599 c, t dbSNP:571384931
1601 1601 a, c, t dbSNP:764254051
1602 1602 a, g dbSNP:551306856
1612 1612 c, t dbSNP:753082199
1613 1613 a, g dbSNP:768103022
1628 1628 -, t dbSNP:754323537
1633 1633 a, g dbSNP:759773949
1634 1634 a, c dbSNP:774758564
1636 1636 g, t dbSNP:766770838
1641 1641 a, g dbSNP:761450468
1650 1650 g, t dbSNP:72657557
1657 1657 c, g dbSNP:771547810
1662 1662 a, g dbSNP:745800866
1679 1679 c, t dbSNP:774440622
1683 1683 c, t dbSNP:369382063
1684 1684 -, ctc dbSNP:764522890
1692 1692 a, t dbSNP:749129164
1696 1696 g, t dbSNP:778094266
1704 1704 g, t dbSNP:756340988
1710 1710 a, g dbSNP:748362963
1715 1715 c, t dbSNP:113622727
1716 1716 a, g dbSNP:72657556
1717 1717 a, g dbSNP:752007565
1724 1724 c, t dbSNP:201873521
1729 1729 c, t dbSNP:146304310
1730 1730 a, g dbSNP:201693951
1732 1732 a, g dbSNP:751095051
1738 1738 -, c dbSNP:756434927
1738 1738 c, t dbSNP:766030532
1741 1741 c, t dbSNP:762984684
1742 1742 c, g dbSNP:773081415
1747 1747 c, t dbSNP:769574907
1751 1751 c, g dbSNP:761519316
1754 1754 a, c, g dbSNP:768842453
1759 1759 c, t dbSNP:747270695
1763 1763 c, t dbSNP:775543049
1764 1764 a, g, t dbSNP:372568407
1766 1766 c, t dbSNP:5742912
1770 1770 c, t dbSNP:757598099
1773 1773 c, t dbSNP:148749888
1774 1774 a, g, t dbSNP:3764873
1775 1775 a, g dbSNP:200923755
1782 1782 c, t dbSNP:765978258
1793 1793 g, t dbSNP:760463562
1794 1794 c, t dbSNP:775589042
1809 1809 c, t dbSNP:148959452
1810 1810 a, g dbSNP:368914240
1811 1811 c, g, t dbSNP:137852634
1812 1812 a, g dbSNP:763359949
1828 1828 c, t dbSNP:138108545
1829 1829 a, g dbSNP:770217992
1837 1837 -, caa dbSNP:753073959
1843 1843 a, g dbSNP:570566104
1848 1848 a, c, g dbSNP:72657550
1852 1852 a, g dbSNP:748814591
1856 1856 a, c dbSNP:777311526
1857 1857 a, g dbSNP:756012753
1868 1868 g, t dbSNP:752700795
1871 1871 -, ttc dbSNP:61759913
1877 1877 c, g dbSNP:780837673
1888 1888 c, t dbSNP:374460984
1890 1890 a, g dbSNP:754815751
1894 1894 c, g dbSNP:751665454
1899 1899 c, t dbSNP:11542843
1917 1917 c, t dbSNP:72657549
1923 1923 c, t dbSNP:757414357
1933 1933 a, g dbSNP:754353092
1936 1936 a, c dbSNP:764684762
1946 1946 a, g dbSNP:761134966
1957 1957 c, g dbSNP:775891291
1963 1963 a, g dbSNP:767835625
1966 1966 c, t dbSNP:762582819
1967 1967 a, g dbSNP:772866436
1974 1974 c, t dbSNP:137852635
1975 1975 a, g dbSNP:199526819
1980 1980 c, t dbSNP:766598472
1982 1982 a, t dbSNP:200443896
1986 1986 c, t dbSNP:768620050
1987 1987 g, t dbSNP:746962921
1995 1995 c, t dbSNP:72657541
1996 1996 a, g dbSNP:779896951
1998 1998 c, g dbSNP:758279404
2005 2005 c, t dbSNP:559461583
2006 2006 a, c, g dbSNP:59142484
2007 2007 c, g, t dbSNP:764120076
2018 2018 a, c dbSNP:756639079
2021 2021 a, g dbSNP:753200672
2022 2022 c, t dbSNP:367983061
2026 2026 c, g dbSNP:759899427
2027 2027 a, g dbSNP:750038511
2028 2028 c, t dbSNP:764895703
2045 2045 c, g dbSNP:761506062
2046 2046 a, g dbSNP:545954539
2050 2050 g, t dbSNP:201759987
2051 2051 g, t dbSNP:760600959
2055 2055 a, g dbSNP:775290860
2060 2060 c, t dbSNP:771949339
2061 2061 a, g dbSNP:140175017
2076 2076 a, g dbSNP:778899652
2078 2078 c, t dbSNP:771246219
2079 2079 a, g, t dbSNP:202038572
2082 2082 a, g dbSNP:756163525
2083 2083 a, g dbSNP:200891555
2085 2085 c, g dbSNP:72657540
2089 2089 a, g dbSNP:781687956
2090 2090 c, g dbSNP:755287192
2094 2094 c, t dbSNP:751903373
2096 2096 c, t dbSNP:766773131
2110 2110 c, t dbSNP:761525147
2125 2125 c, t dbSNP:753494970
2130 2130 -, c dbSNP:773139153
2142 2142 g, t dbSNP:3741913
2143 2143 c, t dbSNP:543479270
2145 2145 a, c, t dbSNP:775445715
2148 2148 -, acc dbSNP:769618870
2155 2155 a, g dbSNP:772108915
2161 2161 a, g dbSNP:574617472
2178 2178 a, g dbSNP:774283066
2182 2182 c, t dbSNP:561526745
2183 2183 c, g dbSNP:749467368
2202 2202 c, t dbSNP:773040403
2203 2203 a, t dbSNP:777865080
2210 2210 a, c dbSNP:769880079
2212 2212 c, t dbSNP:748199518
2214 2214 a, c dbSNP:781302181
2224 2224 c, t dbSNP:370406973
2226 2226 a, c dbSNP:752130523
2229 2229 c, t dbSNP:780386780
2232 2232 a, g dbSNP:758691159
2237 2237 c, t dbSNP:753487231
2238 2238 a, g dbSNP:367681929
2251 2251 a, g dbSNP:573049175
2252 2252 a, g dbSNP:761654238
2255 2255 c, t dbSNP:752223228
2258 2258 a, g dbSNP:767202786
2275 2275 a, c, g, t dbSNP:17846607
2276 2276 a, g, t dbSNP:2228576
2277 2277 c, t dbSNP:762689971
2285 2285 c, t dbSNP:773435718
2287 2287 c, g, t dbSNP:748445983
2289 2289 c, g dbSNP:776691555
2293 2293 -, g dbSNP:776347074
2293 2293 a, g, t dbSNP:539360032
2293 2293 -, g dbSNP:761663786
2294 2294 c, g dbSNP:576872942
2295 2295 c, t dbSNP:780566959
2298 2298 a, g dbSNP:758737621
2303 2303 a, g dbSNP:557017986
2306 2306 a, g dbSNP:779371939
2308 2308 a, g dbSNP:72657539
2312 2312 a, g dbSNP:538153841
2315 2315 g, t dbSNP:767075981
2316 2316 -, t dbSNP:768399005
2324 2324 c, g, t dbSNP:746692672
2337 2337 c, t dbSNP:779629530
2342 2342 a, g dbSNP:370593306
2343 2343 g, t dbSNP:762996681
2346 2346 c, g dbSNP:772855083
2350 2350 a, g dbSNP:377669906
2361 2361 c, t dbSNP:753378218
2362 2362 a, g dbSNP:188694128
2369 2369 c, t dbSNP:72657538
2375 2375 a, g dbSNP:183604895
2400 2400 c, t dbSNP:553848085
2402 2402 c, t dbSNP:566145784
2412 2412 c, t dbSNP:62620999
2433 2433 c, t dbSNP:532711891
2457 2457 c, t dbSNP:188712065
2466 2466 a, g dbSNP:762326102
2503 2503 c, g dbSNP:549794482
2556 2556 a, g dbSNP:374436303
2562 2562 a, g dbSNP:751999385
2595 2595 c, t dbSNP:55981728
2596 2596 a, g dbSNP:370775523
2635 2635 a, g dbSNP:72657537
2648 2648 a, t dbSNP:541167039
2651 2651 a, g dbSNP:72657536
2664 2664 g, t dbSNP:572951397
2698 2698 a, c dbSNP:536027120
2701 2701 c, t dbSNP:559298639
2702 2702 a, g dbSNP:781720164
2722 2722 c, t dbSNP:755355408
2735 2735 c, t dbSNP:751853944
2766 2766 a, c dbSNP:140681881
2791 2791 -, c dbSNP:71450140
2808 2808 g, t dbSNP:150966071
2836 2836 c, t dbSNP:72657535
2850 2850 c, g dbSNP:766654014
2864 2864 c, t dbSNP:72657534
2865 2865 g, t dbSNP:762950321
2887 2887 a, g dbSNP:192846033
2907 2907 c, t dbSNP:750585112
2926 2926 g, t dbSNP:765221861
2931 2931 a, g dbSNP:571203740
2932 2932 g, t dbSNP:62618735
2936 2936 c, t dbSNP:554603722
3002 3002 c, g dbSNP:534430419
3026 3026 a, g dbSNP:549856051
3027 3027 c, t dbSNP:566231983
3064 3064 g, t dbSNP:539591533
3111 3111 a, g dbSNP:72657533
3149 3149 c, t dbSNP:62627411
3168 3168 a, c dbSNP:532769452
3176 3176 c, t dbSNP:776872762
3179 3179 -, t dbSNP:771076540
3213 3213 a, g dbSNP:62619209
3219 3219 c, t dbSNP:72657532
3223 3223 c, t dbSNP:771824185
3246 3246 a, g dbSNP:745491988
3263 3263 a, g dbSNP:72657531
3275 3275 a, g dbSNP:773959273
3287 3287 c, g dbSNP:72657530
3291 3291 c, g dbSNP:777923311
3311 3311 -, tgtt dbSNP:58510764
3311 3311 -, tgtt dbSNP:398088152
3317 3317 -, ttg dbSNP:201016824
3326 3326 a, g dbSNP:547833935

Target ORF information:

RefSeq Version NM_001038
Organism Homo sapiens (human)
Definition Homo sapiens sodium channel, non voltage gated 1 alpha subunit (SCNN1A), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001038

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
ATGGAGGGGA ACAAGCTGGA GGAGCAGGAC TCTAGCCCTC CACAGTCCAC TCCAGGGCTC 
ATGAAGGGGA ACAAGCGTGA GGAGCAGGGG CTGGGCCCCG AACCTGCGGC GCCCCAGCAG
CCCACGGCGG AGGAGGAGGC CCTGATCGAG TTCCACCGCT CCTACCGAGA GCTCTTCGAG
TTCTTCTGCA ACAACACCAC CATCCACGGC GCCATCCGCC TGGTGTGCTC CCAGCACAAC
CGCATGAAGA CGGCCTTCTG GGCAGTGCTG TGGCTCTGCA CCTTTGGCAT GATGTACTGG
CAATTCGGCC TGCTTTTCGG AGAGTACTTC AGCTACCCCG TCAGCCTCAA CATCAACCTC
AACTCGGACA AGCTCGTCTT CCCCGCAGTG ACCATCTGCA CCCTCAATCC CTACAGGTAC
CCGGAAATTA AAGAGGAGCT GGAGGAGCTG GACCGCATCA CAGAGCAGAC GCTCTTTGAC
CTGTACAAAT ACAGCTCCTT CACCACTCTC GTGGCCGGCT CCCGCAGCCG TCGCGACCTG
CGGGGGACTC TGCCGCACCC CTTGCAGCGC CTGAGGGTCC CGCCCCCGCC TCACGGGGCC
CGTCGAGCCC GTAGCGTGGC CTCCAGCTTG CGGGACAACA ACCCCCAGGT GGACTGGAAG
GACTGGAAGA TCGGCTTCCA GCTGTGCAAC CAGAACAAAT CGGACTGCTT CTACCAGACA
TACTCATCAG GGGTGGATGC GGTGAGGGAG TGGTACCGCT TCCACTACAT CAACATCCTG
TCGAGGCTGC CAGAGACTCT GCCATCCCTG GAGGAGGACA CGCTGGGCAA CTTCATCTTC
GCCTGCCGCT TCAACCAGGT CTCCTGCAAC CAGGCGAATT ACTCTCACTT CCACCACCCG
ATGTATGGAA ACTGCTATAC TTTCAATGAC AAGAACAACT CCAACCTCTG GATGTCTTCC
ATGCCTGGAA TCAACAACGG TCTGTCCCTG ATGCTGCGCG CAGAGCAGAA TGACTTCATT
CCCCTGCTGT CCACAGTGAC TGGGGCCCGG GTAATGGTGC ACGGGCAGGA TGAACCTGCC
TTTATGGATG ATGGTGGCTT TAACTTGCGG CCTGGCGTGG AGACCTCCAT CAGCATGAGG
AAGGAAACCC TGGACAGACT TGGGGGCGAT TATGGCGACT GCACCAAGAA TGGCAGTGAT
GTTCCTGTTG AGAACCTTTA CCCTTCAAAG TACACACAGC AGGTGTGTAT TCACTCCTGC
TTCCAGGAGA GCATGATCAA GGAGTGTGGC TGTGCCTACA TCTTCTATCC GCGGCCCCAG
AACGTGGAGT ACTGTGACTA CAGAAAGCAC AGTTCCTGGG GGTACTGCTA CTATAAGCTC
CAGGTTGACT TCTCCTCAGA CCACCTGGGC TGTTTCACCA AGTGCCGGAA GCCATGCAGC
GTGACCAGCT ACCAGCTCTC TGCTGGTTAC TCACGATGGC CCTCGGTGAC ATCCCAGGAA
TGGGTCTTCC AGATGCTATC GCGACAGAAC AATTACACCG TCAACAACAA GAGAAATGGA
GTGGCCAAAG TCAACATCTT CTTCAAGGAG CTGAACTACA AAACCAATTC TGAGTCTCCC
TCTGTCACGA TGGTCACCCT CCTGTCCAAC CTGGGCAGCC AGTGGAGCCT GTGGTTCGGC
TCCTCGGTGT TGTCTGTGGT GGAGATGGCT GAGCTCGTCT TTGACCTGCT GGTCATCATG
TTCCTCATGC TGCTCCGAAG GTTCCGAAGC CGATACTGGT CTCCAGGCCG AGGGGGCAGG
GGTGCTCAGG AGGTAGCCTC CACCCTGGCA TCCTCCCCTC CTTCCCACTT CTGCCCCCAC
CCCATGTCTC TGTCCTTGTC CCAGCCAGGC CCTGCTCCCT CTCCAGCCTT GACAGCCCCT
CCCCCTGCCT ATGCCACCCT GGGCCCCCGC CCATCTCCAG GGGGCTCTGC AGGGGCCAGT
TCCTCCACCT GTCCTCTGGG GGGGCCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu14485
Accession Version NM_001159575.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2079bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product amiloride-sensitive sodium channel subunit alpha isoform 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK304379.1, X76180.1 and BU680600.1. Summary: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009]. Transcript Variant: This variant (3) contains an alternate exon in the 5' coding region, and uses an in-frame upstream start codon compared to variant 1. This results in an isoform (3) with a longer N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK304379.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGAGCAGTA TCAAGGGGAA CAAGCTGGAG GAGCAGGACC CTAGACCTCT GCAGCCCATA 
CCAGGTCTCA TGGAGGGGAA CAAGCTGGAG GAGCAGGACT CTAGCCCTCC ACAGTCCACT
CCAGGGCTCA TGAAGGGGAA CAAGCGTGAG GAGCAGGGGC TGGGCCCCGA ACCTGCGGCG
CCCCAGCAGC CCACGGCGGA GGAGGAGGCC CTGATCGAGT TCCACCGCTC CTACCGAGAG
CTCTTCGAGT TCTTCTGCAA CAACACCACC ATCCACGGCG CCATCCGCCT GGTGTGCTCC
CAGCACAACC GCATGAAGAC GGCCTTCTGG GCAGTGCTGT GGCTCTGCAC CTTTGGCATG
ATGTACTGGC AATTCGGCCT GCTTTTCGGA GAGTACTTCA GCTACCCCGT CAGCCTCAAC
ATCAACCTCA ACTCGGACAA GCTCGTCTTC CCCGCAGTGA CCATCTGCAC CCTCAATCCC
TACAGGTACC CGGAAATTAA AGAGGAGCTG GAGGAGCTGG ACCGCATCAC AGAGCAGACG
CTCTTTGACC TGTACAAATA CAGCTCCTTC ACCACTCTCG TGGCCGGCTC CCGCAGCCGT
CGCGACCTGC GGGGGACTCT GCCGCACCCC TTGCAGCGCC TGAGGGTCCC GCCCCCGCCT
CACGGGGCCC GTCGAGCCCG TAGCGTGGCC TCCAGCTTGC GGGACAACAA CCCCCAGGTG
GACTGGAAGG ACTGGAAGAT CGGCTTCCAG CTGTGCAACC AGAACAAATC GGACTGCTTC
TACCAGACAT ACTCATCAGG GGTGGATGCG GTGAGGGAGT GGTACCGCTT CCACTACATC
AACATCCTGT CGAGGCTGCC AGAGACTCTG CCATCCCTGG AGGAGGACAC GCTGGGCAAC
TTCATCTTCG CCTGCCGCTT CAACCAGGTC TCCTGCAACC AGGCGAATTA CTCTCACTTC
CACCACCCGA TGTATGGAAA CTGCTATACT TTCAATGACA AGAACAACTC CAACCTCTGG
ATGTCTTCCA TGCCTGGAAT CAACAACGGT CTGTCCCTGA TGCTGCGCGC AGAGCAGAAT
GACTTCATTC CCCTGCTGTC CACAGTGACT GGGGCCCGGG TAATGGTGCA CGGGCAGGAT
GAACCTGCCT TTATGGATGA TGGTGGCTTT AACTTGCGGC CTGGCGTGGA GACCTCCATC
AGCATGAGGA AGGAAACCCT GGACAGACTT GGGGGCGATT ATGGCGACTG CACCAAGAAT
GGCAGTGATG TTCCTGTTGA GAACCTTTAC CCTTCAAAGT ACACACAGCA GGTGTGTATT
CACTCCTGCT TCCAGGAGAG CATGATCAAG GAGTGTGGCT GTGCCTACAT CTTCTATCCG
CGGCCCCAGA ACGTGGAGTA CTGTGACTAC AGAAAGCACA GTTCCTGGGG GTACTGCTAC
TATAAGCTCC AGGTTGACTT CTCCTCAGAC CACCTGGGCT GTTTCACCAA GTGCCGGAAG
CCATGCAGCG TGACCAGCTA CCAGCTCTCT GCTGGTTACT CACGATGGCC CTCGGTGACA
TCCCAGGAAT GGGTCTTCCA GATGCTATCG CGACAGAACA ATTACACCGT CAACAACAAG
AGAAATGGAG TGGCCAAAGT CAACATCTTC TTCAAGGAGC TGAACTACAA AACCAATTCT
GAGTCTCCCT CTGTCACGAT GGTCACCCTC CTGTCCAACC TGGGCAGCCA GTGGAGCCTG
TGGTTCGGCT CCTCGGTGTT GTCTGTGGTG GAGATGGCTG AGCTCGTCTT TGACCTGCTG
GTCATCATGT TCCTCATGCT GCTCCGAAGG TTCCGAAGCC GATACTGGTC TCCAGGCCGA
GGGGGCAGGG GTGCTCAGGA GGTAGCCTCC ACCCTGGCAT CCTCCCCTCC TTCCCACTTC
TGCCCCCACC CCATGTCTCT GTCCTTGTCC CAGCCAGGCC CTGCTCCCTC TCCAGCCTTG
ACAGCCCCTC CCCCTGCCTA TGCCACCCTG GGCCCCCGCC CATCTCCAGG GGGCTCTGCA
GGGGCCAGTT CCTCCACCTG TCCTCTGGGG GGGCCCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001153047.1
CDS92..2170
Misc Feature(1)53..55(+)
Misc Feature(2)320..2101(+)
Misc Feature(3)344..1876(+)
Exon (1)1..106
Gene:SCNN1A
Gene Synonym:
Exon (2)107..576
Gene:SCNN1A
Gene Synonym:
Exon (3)577..844
Gene:SCNN1A
Gene Synonym:
Exon (4)845..1035
Gene:SCNN1A
Gene Synonym:
Exon (5)1036..1139
Gene:SCNN1A
Gene Synonym:
Exon (6)1140..1303
Gene:SCNN1A
Gene Synonym:
Exon (7)1304..1402
Gene:SCNN1A
Gene Synonym:
Exon (8)1403..1520
Gene:SCNN1A
Gene Synonym:
Exon (9)1521..1599
Gene:SCNN1A
Gene Synonym:
Exon (10)1600..1657
Gene:SCNN1A
Gene Synonym:
Exon (11)1658..1713
Gene:SCNN1A
Gene Synonym:
Exon (12)1714..1789
Gene:SCNN1A
Gene Synonym:
Exon (13)1790..3200
Gene:SCNN1A
Gene Synonym:
Translation
Position Chain Variation Link
1 1 a, c dbSNP:138378091
63 63 c, t dbSNP:72645154
72 72 c, g dbSNP:771754297
73 73 c, g dbSNP:557040840
87 87 c, g dbSNP:778939157
113 113 a, g dbSNP:150809388
117 117 c, t dbSNP:776787803
133 133 c, t dbSNP:61759919
136 136 a, g dbSNP:369609706
138 138 c, g dbSNP:377074479
140 140 c, t dbSNP:556247628
143 143 a, c dbSNP:772741031
144 144 -, a dbSNP:772085907
156 156 c, g dbSNP:746190692
162 162 c, t dbSNP:779394345
163 163 a, g dbSNP:111550798
166 166 a, g dbSNP:757599210
168 168 a, g dbSNP:752387748
169 169 a, g dbSNP:780762241
184 184 a, g dbSNP:754452040
186 186 a, g dbSNP:142937915
188 188 a, g dbSNP:766263579
190 190 c, t dbSNP:762899862
193 193 -, t dbSNP:751119251
196 196 a, c dbSNP:372909867
217 217 a, g dbSNP:750401022
219 219 c, t dbSNP:765012846
222 222 c, t dbSNP:761572575
231 231 a, g dbSNP:148581573
234 234 a, g dbSNP:768767909
237 237 a, c, g, t dbSNP:72645127
251 251 a, c, t dbSNP:775062010
252 252 c, t dbSNP:771310951
253 253 a, g dbSNP:749626049
259 259 c, t dbSNP:13306619
260 260 a, g dbSNP:72645126
263 263 a, c dbSNP:746472088
265 265 c, t dbSNP:779509123
266 266 a, g dbSNP:757970565
267 267 c, t dbSNP:750349787
268 268 a, g dbSNP:765101499
270 270 c, t dbSNP:757014172
271 271 a, g dbSNP:571296830
284 284 a, g dbSNP:551220820
286 286 a, g dbSNP:138995556
287 287 a, g dbSNP:146187461
288 288 c, g, t dbSNP:759745474
289 289 a, g dbSNP:375919815
291 291 a, c dbSNP:771345288
293 293 c, g dbSNP:200068111
303 303 g, t dbSNP:185241340
307 307 a, c, t dbSNP:200770604
308 308 c, g dbSNP:779740460
317 317 c, t dbSNP:757847873
318 318 a, g dbSNP:201823143
326 326 c, t dbSNP:778872550
337 337 c, t dbSNP:560437072
343 343 a, c dbSNP:61758859
352 352 c, t dbSNP:757166697
354 354 a, c dbSNP:753866692
358 358 a, c dbSNP:374032839
363 363 -, tc dbSNP:765835593
367 367 c, t dbSNP:756036616
368 368 g, t dbSNP:370299321
369 369 c, g dbSNP:752951128
370 370 a, c, t dbSNP:368475363
371 371 a, g dbSNP:540601108
373 373 c, t dbSNP:374270705
376 376 c, t dbSNP:138613452
377 377 c, t dbSNP:763345732
382 382 a, g dbSNP:773836542
384 384 g, t dbSNP:770042605
390 390 c, t dbSNP:762180968
401 401 c, t dbSNP:61759860
405 405 g, t dbSNP:775058248
409 409 a, g dbSNP:371611492
412 412 a, g dbSNP:376913356
422 422 a, g dbSNP:778268845
432 432 g, t dbSNP:770518117
441 441 c, t dbSNP:749174523
445 445 c, t dbSNP:777820681
451 451 a, c, g dbSNP:752542101
458 458 c, g, t dbSNP:755271752
461 461 c, t dbSNP:751856853
466 466 c, t dbSNP:766337568
469 469 c, t dbSNP:763151595
472 472 c, g dbSNP:750838338
478 478 c, t dbSNP:148261445
479 479 a, g dbSNP:144763378
483 483 a, t dbSNP:777004900
489 489 c, t dbSNP:769061042
497 497 a, c, g dbSNP:774123732
499 499 c, t dbSNP:770329720
500 500 a, g dbSNP:61759861
506 506 c, t dbSNP:777501442
511 511 c, t dbSNP:769881891
516 516 a, g dbSNP:747901081
519 519 a, t dbSNP:575699161
523 523 a, c, t dbSNP:751718311
526 526 a, g dbSNP:373834849
529 529 c, g dbSNP:758345341
535 535 c, t dbSNP:750550104
537 537 -, t dbSNP:757895343
544 544 -, c dbSNP:754230610
544 544 c, t dbSNP:765686184
545 545 a, g, t dbSNP:141756749
549 549 c, t dbSNP:764441874
553 553 c, t dbSNP:761155056
559 559 c, t dbSNP:773813638
563 563 c, g dbSNP:766056130
568 568 c, t dbSNP:762326874
571 571 -, c dbSNP:764479792
576 576 a, g dbSNP:370256768
578 578 g, t dbSNP:564898684
595 595 a, g dbSNP:776644104
597 597 a, g dbSNP:768671376
604 604 -, ggagctgga dbSNP:760971071
612 612 a, g dbSNP:746734280
617 617 a, t dbSNP:775335440
626 626 c, g dbSNP:771805486
631 631 a, g dbSNP:746089331
638 638 a, g dbSNP:779168356
640 640 c, g dbSNP:757265424
641 641 a, c dbSNP:749370935
644 644 c, t dbSNP:201532601
648 648 a, c dbSNP:756664267
649 649 a, c dbSNP:753190765
650 650 c, t dbSNP:781587925
659 659 c, t dbSNP:755365105
684 684 a, g dbSNP:750086795
685 685 c, t dbSNP:764986095
700 700 g, t dbSNP:55859427
701 701 a, c, t dbSNP:55797039
703 703 a, g dbSNP:148904855
704 704 a, g dbSNP:775360187
706 706 -, g dbSNP:775723647
706 706 g, t dbSNP:771891536
715 715 a, g dbSNP:759343629
719 719 c, t dbSNP:774485921
723 723 a, t dbSNP:771170845
727 727 g, t dbSNP:199573198
728 728 c, t dbSNP:201246087
734 734 -, a dbSNP:767638989
735 735 c, g dbSNP:769803163
736 736 c, g dbSNP:574592585
739 739 a, c dbSNP:554754589
742 742 a, g dbSNP:755303181
747 747 c, t dbSNP:752004499
749 749 c, t dbSNP:778660547
754 754 c, t dbSNP:372705087
755 755 c, g dbSNP:753587879
758 758 -, g dbSNP:759611286
761 761 a, c, g, t dbSNP:752626882
768 768 c, t dbSNP:767356889
770 770 c, t dbSNP:759283975
774 774 a, g dbSNP:147866964
778 778 a, g dbSNP:770760088
779 779 g, t dbSNP:763129361
781 781 a, c dbSNP:773372073
785 785 a, c dbSNP:769902968
787 787 a, c dbSNP:748189603
789 789 g, t dbSNP:781695328
803 803 a, c, t dbSNP:747570345
808 808 a, g dbSNP:780536807
809 809 a, c, g dbSNP:200510319
812 812 a, g dbSNP:748960792
814 814 a, c dbSNP:767902038
819 819 a, g dbSNP:755588373
823 823 c, g dbSNP:748173628
829 829 c, g dbSNP:767436357
830 830 -, atc dbSNP:774475900
832 832 a, c dbSNP:754885393
838 838 a, c dbSNP:751536696
842 842 c, t dbSNP:766160514
855 855 a, g dbSNP:765128439
861 861 c, t dbSNP:761907917
862 862 a, g dbSNP:776977349
866 866 g, t dbSNP:764253958
872 872 c, t dbSNP:760847083
887 887 c, t dbSNP:776069930
888 888 c, t dbSNP:772732812
900 900 c, t dbSNP:746199428
901 901 a, g dbSNP:574585318
906 906 a, g dbSNP:142409152
908 908 g, t dbSNP:747753624
914 914 -, t dbSNP:769580746
915 915 a, g dbSNP:180729483
917 917 c, t dbSNP:771168777
918 918 a, g dbSNP:72645111
924 924 a, g dbSNP:551706206
927 927 a, g dbSNP:746527103
929 929 a, c dbSNP:779918209
931 931 c, t dbSNP:758245407
938 938 c, t dbSNP:750414125
943 943 a, g dbSNP:72645110
948 948 c, t dbSNP:757131301
952 952 a, g dbSNP:754052676
957 957 c, g dbSNP:781146561
965 965 c, t dbSNP:147702347
966 966 c, t dbSNP:72645109
971 971 a, g dbSNP:375898173
974 974 -, g dbSNP:747904876
981 981 c, t dbSNP:150033111
982 982 a, g dbSNP:372634287
986 986 g, t dbSNP:759933475
998 998 c, t dbSNP:774991447
999 999 c, t dbSNP:771188060
1000 1000 c, t dbSNP:139335335
1001 1001 a, c, g, t dbSNP:201553658
1002 1002 c, t dbSNP:779507200
1006 1006 a, c dbSNP:771678842
1007 1007 c, t dbSNP:745777993
1008 1008 a, g dbSNP:368942111
1009 1009 c, t dbSNP:770607083
1020 1020 c, t dbSNP:749335164
1024 1024 -, c dbSNP:780827736
1035 1035 a, c, t dbSNP:778088118
1045 1045 c, t dbSNP:754948204
1055 1055 c, t dbSNP:751693113
1057 1057 c, t dbSNP:766747041
1059 1059 c, t dbSNP:755217190
1063 1063 c, g dbSNP:750994375
1066 1066 c, t dbSNP:765571538
1071 1071 a, t dbSNP:762177076
1076 1076 a, t dbSNP:764914260
1077 1077 a, t dbSNP:774936628
1078 1078 c, t dbSNP:767227687
1095 1095 a, c dbSNP:758918630
1098 1098 a, g dbSNP:773885589
1112 1112 a, c dbSNP:770392706
1113 1113 g, t dbSNP:749237003
1136 1136 a, g dbSNP:773342959
1138 1138 c, t dbSNP:61731141
1146 1146 c, g dbSNP:779341775
1151 1151 a, t dbSNP:757735280
1157 1157 c, t dbSNP:146177203
1158 1158 a, g dbSNP:778199680
1159 1159 c, t dbSNP:756498521
1160 1160 a, g dbSNP:11542844
1165 1165 a, g dbSNP:766136849
1169 1169 a, g dbSNP:375310967
1170 1170 a, g dbSNP:749978185
1175 1175 g, t dbSNP:764889782
1183 1183 c, g dbSNP:371971622
1195 1195 a, g dbSNP:199671336
1196 1196 a, g dbSNP:768438286
1198 1198 g, t dbSNP:760389728
1207 1207 c, t dbSNP:775647330
1208 1208 c, g, t dbSNP:181065138
1209 1209 a, g, t dbSNP:534158738
1212 1212 c, t dbSNP:139861603
1216 1216 c, g dbSNP:778158546
1219 1219 g, t dbSNP:571599047
1221 1221 a, g dbSNP:753035419
1222 1222 c, t dbSNP:199947703
1223 1223 a, c, g dbSNP:189376498
1224 1224 c, g dbSNP:764826366
1226 1226 c, t dbSNP:761243273
1227 1227 a, g dbSNP:753740830
1233 1233 a, g dbSNP:569195112
1234 1234 a, g dbSNP:149430403
1235 1235 a, c, t dbSNP:767336946
1238 1238 a, g, t dbSNP:375159701
1239 1239 c, t dbSNP:770990050
1266 1266 g, t dbSNP:749335890
1267 1267 c, g dbSNP:369734906
1268 1268 c, t dbSNP:529383103
1269 1269 a, g dbSNP:372873824
1276 1276 c, t dbSNP:567003433
1277 1277 a, g dbSNP:368471914
1284 1284 c, t dbSNP:755461944
1289 1289 a, g dbSNP:193920773
1299 1299 a, g dbSNP:778711245
1308 1308 c, t dbSNP:777289941
1309 1309 a, c dbSNP:769075036
1314 1314 a, g dbSNP:201214012
1320 1320 c, t dbSNP:373986349
1327 1327 c, t dbSNP:756833708
1328 1328 a, g dbSNP:200557019
1333 1333 c, t dbSNP:777139886
1336 1336 c, t dbSNP:72657575
1343 1343 a, g dbSNP:201365745
1344 1344 c, g dbSNP:767449498
1345 1345 a, c, g dbSNP:202151383
1348 1348 a, g dbSNP:754732154
1350 1350 a, g dbSNP:751381592
1357 1357 a, t dbSNP:766246552
1360 1360 a, t dbSNP:763054871
1365 1365 a, c dbSNP:13306616
1375 1375 c, t dbSNP:765219923
1376 1376 a, c, t dbSNP:149484264
1382 1382 c, t dbSNP:769308083
1388 1388 a, g dbSNP:761309529
1400 1400 c, t dbSNP:138011635
1435 1435 g, t dbSNP:768222573
1449 1449 a, g dbSNP:200026546
1452 1452 a, g dbSNP:780056168
1458 1458 a, g dbSNP:758087809
1459 1459 c, t dbSNP:375712066
1460 1460 a, c dbSNP:778899717
1465 1465 -, c dbSNP:758014063
1467 1467 a, c dbSNP:372997123
1470 1470 c, t dbSNP:571384931
1472 1472 a, c, t dbSNP:764254051
1473 1473 a, g dbSNP:551306856
1483 1483 c, t dbSNP:753082199
1484 1484 a, g dbSNP:768103022
1499 1499 -, t dbSNP:754323537
1504 1504 a, g dbSNP:759773949
1505 1505 a, c dbSNP:774758564
1507 1507 g, t dbSNP:766770838
1512 1512 a, g dbSNP:761450468
1521 1521 g, t dbSNP:72657557
1528 1528 c, g dbSNP:771547810
1533 1533 a, g dbSNP:745800866
1550 1550 c, t dbSNP:774440622
1554 1554 c, t dbSNP:369382063
1555 1555 -, ctc dbSNP:764522890
1563 1563 a, t dbSNP:749129164
1567 1567 g, t dbSNP:778094266
1575 1575 g, t dbSNP:756340988
1581 1581 a, g dbSNP:748362963
1586 1586 c, t dbSNP:113622727
1587 1587 a, g dbSNP:72657556
1588 1588 a, g dbSNP:752007565
1595 1595 c, t dbSNP:201873521
1600 1600 c, t dbSNP:146304310
1601 1601 a, g dbSNP:201693951
1603 1603 a, g dbSNP:751095051
1609 1609 -, c dbSNP:756434927
1609 1609 c, t dbSNP:766030532
1612 1612 c, t dbSNP:762984684
1613 1613 c, g dbSNP:773081415
1618 1618 c, t dbSNP:769574907
1622 1622 c, g dbSNP:761519316
1625 1625 a, c, g dbSNP:768842453
1630 1630 c, t dbSNP:747270695
1634 1634 c, t dbSNP:775543049
1635 1635 a, g, t dbSNP:372568407
1637 1637 c, t dbSNP:5742912
1641 1641 c, t dbSNP:757598099
1644 1644 c, t dbSNP:148749888
1645 1645 a, g, t dbSNP:3764873
1646 1646 a, g dbSNP:200923755
1653 1653 c, t dbSNP:765978258
1664 1664 g, t dbSNP:760463562
1665 1665 c, t dbSNP:775589042
1680 1680 c, t dbSNP:148959452
1681 1681 a, g dbSNP:368914240
1682 1682 c, g, t dbSNP:137852634
1683 1683 a, g dbSNP:763359949
1699 1699 c, t dbSNP:138108545
1700 1700 a, g dbSNP:770217992
1708 1708 -, caa dbSNP:753073959
1714 1714 a, g dbSNP:570566104
1719 1719 a, c, g dbSNP:72657550
1723 1723 a, g dbSNP:748814591
1727 1727 a, c dbSNP:777311526
1728 1728 a, g dbSNP:756012753
1739 1739 g, t dbSNP:752700795
1742 1742 -, ttc dbSNP:61759913
1748 1748 c, g dbSNP:780837673
1759 1759 c, t dbSNP:374460984
1761 1761 a, g dbSNP:754815751
1765 1765 c, g dbSNP:751665454
1770 1770 c, t dbSNP:11542843
1788 1788 c, t dbSNP:72657549
1794 1794 c, t dbSNP:757414357
1804 1804 a, g dbSNP:754353092
1807 1807 a, c dbSNP:764684762
1817 1817 a, g dbSNP:761134966
1828 1828 c, g dbSNP:775891291
1834 1834 a, g dbSNP:767835625
1837 1837 c, t dbSNP:762582819
1838 1838 a, g dbSNP:772866436
1845 1845 c, t dbSNP:137852635
1846 1846 a, g dbSNP:199526819
1851 1851 c, t dbSNP:766598472
1853 1853 a, t dbSNP:200443896
1857 1857 c, t dbSNP:768620050
1858 1858 g, t dbSNP:746962921
1866 1866 c, t dbSNP:72657541
1867 1867 a, g dbSNP:779896951
1869 1869 c, g dbSNP:758279404
1876 1876 c, t dbSNP:559461583
1877 1877 a, c, g dbSNP:59142484
1878 1878 c, g, t dbSNP:764120076
1889 1889 a, c dbSNP:756639079
1892 1892 a, g dbSNP:753200672
1893 1893 c, t dbSNP:367983061
1897 1897 c, g dbSNP:759899427
1898 1898 a, g dbSNP:750038511
1899 1899 c, t dbSNP:764895703
1916 1916 c, g dbSNP:761506062
1917 1917 a, g dbSNP:545954539
1921 1921 g, t dbSNP:201759987
1922 1922 g, t dbSNP:760600959
1926 1926 a, g dbSNP:775290860
1931 1931 c, t dbSNP:771949339
1932 1932 a, g dbSNP:140175017
1947 1947 a, g dbSNP:778899652
1949 1949 c, t dbSNP:771246219
1950 1950 a, g, t dbSNP:202038572
1953 1953 a, g dbSNP:756163525
1954 1954 a, g dbSNP:200891555
1956 1956 c, g dbSNP:72657540
1960 1960 a, g dbSNP:781687956
1961 1961 c, g dbSNP:755287192
1965 1965 c, t dbSNP:751903373
1967 1967 c, t dbSNP:766773131
1981 1981 c, t dbSNP:761525147
1996 1996 c, t dbSNP:753494970
2001 2001 -, c dbSNP:773139153
2013 2013 g, t dbSNP:3741913
2014 2014 c, t dbSNP:543479270
2016 2016 a, c, t dbSNP:775445715
2019 2019 -, acc dbSNP:769618870
2026 2026 a, g dbSNP:772108915
2032 2032 a, g dbSNP:574617472
2049 2049 a, g dbSNP:774283066
2053 2053 c, t dbSNP:561526745
2054 2054 c, g dbSNP:749467368
2073 2073 c, t dbSNP:773040403
2074 2074 a, t dbSNP:777865080
2081 2081 a, c dbSNP:769880079
2083 2083 c, t dbSNP:748199518
2085 2085 a, c dbSNP:781302181
2095 2095 c, t dbSNP:370406973
2097 2097 a, c dbSNP:752130523
2100 2100 c, t dbSNP:780386780
2103 2103 a, g dbSNP:758691159
2108 2108 c, t dbSNP:753487231
2109 2109 a, g dbSNP:367681929
2122 2122 a, g dbSNP:573049175
2123 2123 a, g dbSNP:761654238
2126 2126 c, t dbSNP:752223228
2129 2129 a, g dbSNP:767202786
2146 2146 a, c, g, t dbSNP:17846607
2147 2147 a, g, t dbSNP:2228576
2148 2148 c, t dbSNP:762689971
2156 2156 c, t dbSNP:773435718
2158 2158 c, g, t dbSNP:748445983
2160 2160 c, g dbSNP:776691555
2164 2164 -, g dbSNP:776347074
2164 2164 a, g, t dbSNP:539360032
2164 2164 -, g dbSNP:761663786
2165 2165 c, g dbSNP:576872942
2166 2166 c, t dbSNP:780566959
2169 2169 a, g dbSNP:758737621
2174 2174 a, g dbSNP:557017986
2177 2177 a, g dbSNP:779371939
2179 2179 a, g dbSNP:72657539
2183 2183 a, g dbSNP:538153841
2186 2186 g, t dbSNP:767075981
2187 2187 -, t dbSNP:768399005
2195 2195 c, g, t dbSNP:746692672
2208 2208 c, t dbSNP:779629530
2213 2213 a, g dbSNP:370593306
2214 2214 g, t dbSNP:762996681
2217 2217 c, g dbSNP:772855083
2221 2221 a, g dbSNP:377669906
2232 2232 c, t dbSNP:753378218
2233 2233 a, g dbSNP:188694128
2240 2240 c, t dbSNP:72657538
2246 2246 a, g dbSNP:183604895
2271 2271 c, t dbSNP:553848085
2273 2273 c, t dbSNP:566145784
2283 2283 c, t dbSNP:62620999
2304 2304 c, t dbSNP:532711891
2328 2328 c, t dbSNP:188712065
2337 2337 a, g dbSNP:762326102
2374 2374 c, g dbSNP:549794482
2427 2427 a, g dbSNP:374436303
2433 2433 a, g dbSNP:751999385
2466 2466 c, t dbSNP:55981728
2467 2467 a, g dbSNP:370775523
2506 2506 a, g dbSNP:72657537
2519 2519 a, t dbSNP:541167039
2522 2522 a, g dbSNP:72657536
2535 2535 g, t dbSNP:572951397
2569 2569 a, c dbSNP:536027120
2572 2572 c, t dbSNP:559298639
2573 2573 a, g dbSNP:781720164
2593 2593 c, t dbSNP:755355408
2606 2606 c, t dbSNP:751853944
2637 2637 a, c dbSNP:140681881
2662 2662 -, c dbSNP:71450140
2679 2679 g, t dbSNP:150966071
2707 2707 c, t dbSNP:72657535
2721 2721 c, g dbSNP:766654014
2735 2735 c, t dbSNP:72657534
2736 2736 g, t dbSNP:762950321
2758 2758 a, g dbSNP:192846033
2778 2778 c, t dbSNP:750585112
2797 2797 g, t dbSNP:765221861
2802 2802 a, g dbSNP:571203740
2803 2803 g, t dbSNP:62618735
2807 2807 c, t dbSNP:554603722
2873 2873 c, g dbSNP:534430419
2897 2897 a, g dbSNP:549856051
2898 2898 c, t dbSNP:566231983
2935 2935 g, t dbSNP:539591533
2982 2982 a, g dbSNP:72657533
3020 3020 c, t dbSNP:62627411
3039 3039 a, c dbSNP:532769452
3047 3047 c, t dbSNP:776872762
3050 3050 -, t dbSNP:771076540
3084 3084 a, g dbSNP:62619209
3090 3090 c, t dbSNP:72657532
3094 3094 c, t dbSNP:771824185
3117 3117 a, g dbSNP:745491988
3134 3134 a, g dbSNP:72657531
3146 3146 a, g dbSNP:773959273
3158 3158 c, g dbSNP:72657530
3162 3162 c, g dbSNP:777923311
3182 3182 -, tgtt dbSNP:58510764
3182 3182 -, tgtt dbSNP:398088152
3188 3188 -, ttg dbSNP:201016824
3197 3197 a, g dbSNP:547833935

Target ORF information:

RefSeq Version NM_001159575
Organism Homo sapiens (human)
Definition Homo sapiens sodium channel, non voltage gated 1 alpha subunit (SCNN1A), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001159575

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGAGCAGTA TCAAGGGGAA CAAGCTGGAG GAGCAGGACC CTAGACCTCT GCAGCCCATA 
CCAGGTCTCA TGGAGGGGAA CAAGCTGGAG GAGCAGGACT CTAGCCCTCC ACAGTCCACT
CCAGGGCTCA TGAAGGGGAA CAAGCGTGAG GAGCAGGGGC TGGGCCCCGA ACCTGCGGCG
CCCCAGCAGC CCACGGCGGA GGAGGAGGCC CTGATCGAGT TCCACCGCTC CTACCGAGAG
CTCTTCGAGT TCTTCTGCAA CAACACCACC ATCCACGGCG CCATCCGCCT GGTGTGCTCC
CAGCACAACC GCATGAAGAC GGCCTTCTGG GCAGTGCTGT GGCTCTGCAC CTTTGGCATG
ATGTACTGGC AATTCGGCCT GCTTTTCGGA GAGTACTTCA GCTACCCCGT CAGCCTCAAC
ATCAACCTCA ACTCGGACAA GCTCGTCTTC CCCGCAGTGA CCATCTGCAC CCTCAATCCC
TACAGGTACC CGGAAATTAA AGAGGAGCTG GAGGAGCTGG ACCGCATCAC AGAGCAGACG
CTCTTTGACC TGTACAAATA CAGCTCCTTC ACCACTCTCG TGGCCGGCTC CCGCAGCCGT
CGCGACCTGC GGGGGACTCT GCCGCACCCC TTGCAGCGCC TGAGGGTCCC GCCCCCGCCT
CACGGGGCCC GTCGAGCCCG TAGCGTGGCC TCCAGCTTGC GGGACAACAA CCCCCAGGTG
GACTGGAAGG ACTGGAAGAT CGGCTTCCAG CTGTGCAACC AGAACAAATC GGACTGCTTC
TACCAGACAT ACTCATCAGG GGTGGATGCG GTGAGGGAGT GGTACCGCTT CCACTACATC
AACATCCTGT CGAGGCTGCC AGAGACTCTG CCATCCCTGG AGGAGGACAC GCTGGGCAAC
TTCATCTTCG CCTGCCGCTT CAACCAGGTC TCCTGCAACC AGGCGAATTA CTCTCACTTC
CACCACCCGA TGTATGGAAA CTGCTATACT TTCAATGACA AGAACAACTC CAACCTCTGG
ATGTCTTCCA TGCCTGGAAT CAACAACGGT CTGTCCCTGA TGCTGCGCGC AGAGCAGAAT
GACTTCATTC CCCTGCTGTC CACAGTGACT GGGGCCCGGG TAATGGTGCA CGGGCAGGAT
GAACCTGCCT TTATGGATGA TGGTGGCTTT AACTTGCGGC CTGGCGTGGA GACCTCCATC
AGCATGAGGA AGGAAACCCT GGACAGACTT GGGGGCGATT ATGGCGACTG CACCAAGAAT
GGCAGTGATG TTCCTGTTGA GAACCTTTAC CCTTCAAAGT ACACACAGCA GGTGTGTATT
CACTCCTGCT TCCAGGAGAG CATGATCAAG GAGTGTGGCT GTGCCTACAT CTTCTATCCG
CGGCCCCAGA ACGTGGAGTA CTGTGACTAC AGAAAGCACA GTTCCTGGGG GTACTGCTAC
TATAAGCTCC AGGTTGACTT CTCCTCAGAC CACCTGGGCT GTTTCACCAA GTGCCGGAAG
CCATGCAGCG TGACCAGCTA CCAGCTCTCT GCTGGTTACT CACGATGGCC CTCGGTGACA
TCCCAGGAAT GGGTCTTCCA GATGCTATCG CGACAGAACA ATTACACCGT CAACAACAAG
AGAAATGGAG TGGCCAAAGT CAACATCTTC TTCAAGGAGC TGAACTACAA AACCAATTCT
GAGTCTCCCT CTGTCACGAT GGTCACCCTC CTGTCCAACC TGGGCAGCCA GTGGAGCCTG
TGGTTCGGCT CCTCGGTGTT GTCTGTGGTG GAGATGGCTG AGCTCGTCTT TGACCTGCTG
GTCATCATGT TCCTCATGCT GCTCCGAAGG TTCCGAAGCC GATACTGGTC TCCAGGCCGA
GGGGGCAGGG GTGCTCAGGA GGTAGCCTCC ACCCTGGCAT CCTCCCCTCC TTCCCACTTC
TGCCCCCACC CCATGTCTCT GTCCTTGTCC CAGCCAGGCC CTGCTCCCTC TCCAGCCTTG
ACAGCCCCTC CCCCTGCCTA TGCCACCCTG GGCCCCCGCC CATCTCCAGG GGGCTCTGCA
GGGGCCAGTT CCTCCACCTG TCCTCTGGGG GGGCCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu14548
Accession Version NM_001159576.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 2187bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product amiloride-sensitive sodium channel subunit alpha isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK172792.1, BC006526.2 and BU680600.1. Summary: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009]. Transcript Variant: This variant (2, also known as alpha-ENaC2) contains an alternate segment in the 5' coding region, and uses an in-frame upstream start codon compared to variant 1. This results in an isoform (2) with a longer N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK172792.1, BC006526.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962346 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGGGCATGG CCAGGGGCAG CCTCACTCGG GTTCCAGGGG TGATGGGAGA GGGCACTCAG 
GGCCCAGAGC TCAGCCTTGA CCCTGACCCT TGCTCTCCCC AATCCACTCC GGGGCTCATG
AAGGGGAACA AGCTGGAGGA GCAGGACCCT AGACCTCTGC AGCCCATACC AGGTCTCATG
GAGGGGAACA AGCTGGAGGA GCAGGACTCT AGCCCTCCAC AGTCCACTCC AGGGCTCATG
AAGGGGAACA AGCGTGAGGA GCAGGGGCTG GGCCCCGAAC CTGCGGCGCC CCAGCAGCCC
ACGGCGGAGG AGGAGGCCCT GATCGAGTTC CACCGCTCCT ACCGAGAGCT CTTCGAGTTC
TTCTGCAACA ACACCACCAT CCACGGCGCC ATCCGCCTGG TGTGCTCCCA GCACAACCGC
ATGAAGACGG CCTTCTGGGC AGTGCTGTGG CTCTGCACCT TTGGCATGAT GTACTGGCAA
TTCGGCCTGC TTTTCGGAGA GTACTTCAGC TACCCCGTCA GCCTCAACAT CAACCTCAAC
TCGGACAAGC TCGTCTTCCC CGCAGTGACC ATCTGCACCC TCAATCCCTA CAGGTACCCG
GAAATTAAAG AGGAGCTGGA GGAGCTGGAC CGCATCACAG AGCAGACGCT CTTTGACCTG
TACAAATACA GCTCCTTCAC CACTCTCGTG GCCGGCTCCC GCAGCCGTCG CGACCTGCGG
GGGACTCTGC CGCACCCCTT GCAGCGCCTG AGGGTCCCGC CCCCGCCTCA CGGGGCCCGT
CGAGCCCGTA GCGTGGCCTC CAGCTTGCGG GACAACAACC CCCAGGTGGA CTGGAAGGAC
TGGAAGATCG GCTTCCAGCT GTGCAACCAG AACAAATCGG ACTGCTTCTA CCAGACATAC
TCATCAGGGG TGGATGCGGT GAGGGAGTGG TACCGCTTCC ACTACATCAA CATCCTGTCG
AGGCTGCCAG AGACTCTGCC ATCCCTGGAG GAGGACACGC TGGGCAACTT CATCTTCGCC
TGCCGCTTCA ACCAGGTCTC CTGCAACCAG GCGAATTACT CTCACTTCCA CCACCCGATG
TATGGAAACT GCTATACTTT CAATGACAAG AACAACTCCA ACCTCTGGAT GTCTTCCATG
CCTGGAATCA ACAACGGTCT GTCCCTGATG CTGCGCGCAG AGCAGAATGA CTTCATTCCC
CTGCTGTCCA CAGTGACTGG GGCCCGGGTA ATGGTGCACG GGCAGGATGA ACCTGCCTTT
ATGGATGATG GTGGCTTTAA CTTGCGGCCT GGCGTGGAGA CCTCCATCAG CATGAGGAAG
GAAACCCTGG ACAGACTTGG GGGCGATTAT GGCGACTGCA CCAAGAATGG CAGTGATGTT
CCTGTTGAGA ACCTTTACCC TTCAAAGTAC ACACAGCAGG TGTGTATTCA CTCCTGCTTC
CAGGAGAGCA TGATCAAGGA GTGTGGCTGT GCCTACATCT TCTATCCGCG GCCCCAGAAC
GTGGAGTACT GTGACTACAG AAAGCACAGT TCCTGGGGGT ACTGCTACTA TAAGCTCCAG
GTTGACTTCT CCTCAGACCA CCTGGGCTGT TTCACCAAGT GCCGGAAGCC ATGCAGCGTG
ACCAGCTACC AGCTCTCTGC TGGTTACTCA CGATGGCCCT CGGTGACATC CCAGGAATGG
GTCTTCCAGA TGCTATCGCG ACAGAACAAT TACACCGTCA ACAACAAGAG AAATGGAGTG
GCCAAAGTCA ACATCTTCTT CAAGGAGCTG AACTACAAAA CCAATTCTGA GTCTCCCTCT
GTCACGATGG TCACCCTCCT GTCCAACCTG GGCAGCCAGT GGAGCCTGTG GTTCGGCTCC
TCGGTGTTGT CTGTGGTGGA GATGGCTGAG CTCGTCTTTG ACCTGCTGGT CATCATGTTC
CTCATGCTGC TCCGAAGGTT CCGAAGCCGA TACTGGTCTC CAGGCCGAGG GGGCAGGGGT
GCTCAGGAGG TAGCCTCCAC CCTGGCATCC TCCCCTCCTT CCCACTTCTG CCCCCACCCC
ATGTCTCTGT CCTTGTCCCA GCCAGGCCCT GCTCCCTCTC CAGCCTTGAC AGCCCCTCCC
CCTGCCTATG CCACCCTGGG CCCCCGCCCA TCTCCAGGGG GCTCTGCAGG GGCCAGTTCC
TCCACCTGTC CTCTGGGGGG GCCCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001153048.1
CDS265..2451
Misc Feature(1)40..42(+)
Misc Feature(2)601..2382(+)
Misc Feature(3)625..2157(+)
Exon (1)1..857
Gene:SCNN1A
Gene Synonym:
Exon (2)858..1125
Gene:SCNN1A
Gene Synonym:
Exon (3)1126..1316
Gene:SCNN1A
Gene Synonym:
Exon (4)1317..1420
Gene:SCNN1A
Gene Synonym:
Exon (5)1421..1584
Gene:SCNN1A
Gene Synonym:
Exon (6)1585..1683
Gene:SCNN1A
Gene Synonym:
Exon (7)1684..1801
Gene:SCNN1A
Gene Synonym:
Exon (8)1802..1880
Gene:SCNN1A
Gene Synonym:
Exon (9)1881..1938
Gene:SCNN1A
Gene Synonym:
Exon (10)1939..1994
Gene:SCNN1A
Gene Synonym:
Exon (11)1995..2070
Gene:SCNN1A
Gene Synonym:
Exon (12)2071..3481
Gene:SCNN1A
Gene Synonym:
Translation
Position Chain Variation Link
61 61 a, g dbSNP:72645129
115 115 a, g dbSNP:186334381
166 166 a, g dbSNP:754708128
171 171 c, t dbSNP:182407119
172 172 a, g dbSNP:72645128
206 206 a, g dbSNP:547416992
237 237 g, t dbSNP:756172397
250 250 c, g dbSNP:145258879
252 252 c, t dbSNP:114961447
254 254 c, t dbSNP:551920451
259 259 g, t dbSNP:752056354
269 269 a, g dbSNP:762536459
270 270 c, t dbSNP:766735096
292 292 c, t dbSNP:531838244
293 293 a, c, g dbSNP:563181534
294 294 c, g dbSNP:760198927
295 295 c, g dbSNP:775099770
302 302 a, g dbSNP:542954120
304 304 g, t dbSNP:759493536
311 311 a, g dbSNP:774191546
314 314 a, c dbSNP:770704975
317 317 c, g dbSNP:113639535
318 318 c, t dbSNP:114264117
327 327 c, t dbSNP:13306618
328 328 a, c dbSNP:748136104
348 348 c, t dbSNP:781311824
349 349 a, g dbSNP:768661347
351 351 c, t dbSNP:747546732
352 352 c, g dbSNP:780765647
359 359 c, t dbSNP:758781865
362 362 c, t dbSNP:189826690
366 366 a, g dbSNP:777530867
370 370 a, g, t dbSNP:752338360
372 372 -, gcagcccata dbSNP:747795149
374 374 c, t dbSNP:61758858
375 375 a, g, t dbSNP:573341191
376 376 a, g dbSNP:766316683
378 378 -, g dbSNP:780727157
378 378 -, g dbSNP:754450034
378 378 g, t dbSNP:762666778
379 379 a, c dbSNP:773021101
383 383 c, t dbSNP:769626485
385 385 a, g dbSNP:557998810
394 394 a, g dbSNP:150809388
398 398 c, t dbSNP:776787803
414 414 c, t dbSNP:61759919
417 417 a, g dbSNP:369609706
419 419 c, g dbSNP:377074479
421 421 c, t dbSNP:556247628
424 424 a, c dbSNP:772741031
425 425 -, a dbSNP:772085907
437 437 c, g dbSNP:746190692
443 443 c, t dbSNP:779394345
444 444 a, g dbSNP:111550798
447 447 a, g dbSNP:757599210
449 449 a, g dbSNP:752387748
450 450 a, g dbSNP:780762241
465 465 a, g dbSNP:754452040
467 467 a, g dbSNP:142937915
469 469 a, g dbSNP:766263579
471 471 c, t dbSNP:762899862
474 474 -, t dbSNP:751119251
477 477 a, c dbSNP:372909867
498 498 a, g dbSNP:750401022
500 500 c, t dbSNP:765012846
503 503 c, t dbSNP:761572575
512 512 a, g dbSNP:148581573
515 515 a, g dbSNP:768767909
518 518 a, c, g, t dbSNP:72645127
532 532 a, c, t dbSNP:775062010
533 533 c, t dbSNP:771310951
534 534 a, g dbSNP:749626049
540 540 c, t dbSNP:13306619
541 541 a, g dbSNP:72645126
544 544 a, c dbSNP:746472088
546 546 c, t dbSNP:779509123
547 547 a, g dbSNP:757970565
548 548 c, t dbSNP:750349787
549 549 a, g dbSNP:765101499
551 551 c, t dbSNP:757014172
552 552 a, g dbSNP:571296830
565 565 a, g dbSNP:551220820
567 567 a, g dbSNP:138995556
568 568 a, g dbSNP:146187461
569 569 c, g, t dbSNP:759745474
570 570 a, g dbSNP:375919815
572 572 a, c dbSNP:771345288
574 574 c, g dbSNP:200068111
584 584 g, t dbSNP:185241340
588 588 a, c, t dbSNP:200770604
589 589 c, g dbSNP:779740460
598 598 c, t dbSNP:757847873
599 599 a, g dbSNP:201823143
607 607 c, t dbSNP:778872550
618 618 c, t dbSNP:560437072
624 624 a, c dbSNP:61758859
633 633 c, t dbSNP:757166697
635 635 a, c dbSNP:753866692
639 639 a, c dbSNP:374032839
644 644 -, tc dbSNP:765835593
648 648 c, t dbSNP:756036616
649 649 g, t dbSNP:370299321
650 650 c, g dbSNP:752951128
651 651 a, c, t dbSNP:368475363
652 652 a, g dbSNP:540601108
654 654 c, t dbSNP:374270705
657 657 c, t dbSNP:138613452
658 658 c, t dbSNP:763345732
663 663 a, g dbSNP:773836542
665 665 g, t dbSNP:770042605
671 671 c, t dbSNP:762180968
682 682 c, t dbSNP:61759860
686 686 g, t dbSNP:775058248
690 690 a, g dbSNP:371611492
693 693 a, g dbSNP:376913356
703 703 a, g dbSNP:778268845
713 713 g, t dbSNP:770518117
722 722 c, t dbSNP:749174523
726 726 c, t dbSNP:777820681
732 732 a, c, g dbSNP:752542101
739 739 c, g, t dbSNP:755271752
742 742 c, t dbSNP:751856853
747 747 c, t dbSNP:766337568
750 750 c, t dbSNP:763151595
753 753 c, g dbSNP:750838338
759 759 c, t dbSNP:148261445
760 760 a, g dbSNP:144763378
764 764 a, t dbSNP:777004900
770 770 c, t dbSNP:769061042
778 778 a, c, g dbSNP:774123732
780 780 c, t dbSNP:770329720
781 781 a, g dbSNP:61759861
787 787 c, t dbSNP:777501442
792 792 c, t dbSNP:769881891
797 797 a, g dbSNP:747901081
800 800 a, t dbSNP:575699161
804 804 a, c, t dbSNP:751718311
807 807 a, g dbSNP:373834849
810 810 c, g dbSNP:758345341
816 816 c, t dbSNP:750550104
818 818 -, t dbSNP:757895343
825 825 -, c dbSNP:754230610
825 825 c, t dbSNP:765686184
826 826 a, g, t dbSNP:141756749
830 830 c, t dbSNP:764441874
834 834 c, t dbSNP:761155056
840 840 c, t dbSNP:773813638
844 844 c, g dbSNP:766056130
849 849 c, t dbSNP:762326874
852 852 -, c dbSNP:764479792
857 857 a, g dbSNP:370256768
859 859 g, t dbSNP:564898684
876 876 a, g dbSNP:776644104
878 878 a, g dbSNP:768671376
885 885 -, ggagctgga dbSNP:760971071
893 893 a, g dbSNP:746734280
898 898 a, t dbSNP:775335440
907 907 c, g dbSNP:771805486
912 912 a, g dbSNP:746089331
919 919 a, g dbSNP:779168356
921 921 c, g dbSNP:757265424
922 922 a, c dbSNP:749370935
925 925 c, t dbSNP:201532601
929 929 a, c dbSNP:756664267
930 930 a, c dbSNP:753190765
931 931 c, t dbSNP:781587925
940 940 c, t dbSNP:755365105
965 965 a, g dbSNP:750086795
966 966 c, t dbSNP:764986095
981 981 g, t dbSNP:55859427
982 982 a, c, t dbSNP:55797039
984 984 a, g dbSNP:148904855
985 985 a, g dbSNP:775360187
987 987 -, g dbSNP:775723647
987 987 g, t dbSNP:771891536
996 996 a, g dbSNP:759343629
1000 1000 c, t dbSNP:774485921
1004 1004 a, t dbSNP:771170845
1008 1008 g, t dbSNP:199573198
1009 1009 c, t dbSNP:201246087
1015 1015 -, a dbSNP:767638989
1016 1016 c, g dbSNP:769803163
1017 1017 c, g dbSNP:574592585
1020 1020 a, c dbSNP:554754589
1023 1023 a, g dbSNP:755303181
1028 1028 c, t dbSNP:752004499
1030 1030 c, t dbSNP:778660547
1035 1035 c, t dbSNP:372705087
1036 1036 c, g dbSNP:753587879
1039 1039 -, g dbSNP:759611286
1042 1042 a, c, g, t dbSNP:752626882
1049 1049 c, t dbSNP:767356889
1051 1051 c, t dbSNP:759283975
1055 1055 a, g dbSNP:147866964
1059 1059 a, g dbSNP:770760088
1060 1060 g, t dbSNP:763129361
1062 1062 a, c dbSNP:773372073
1066 1066 a, c dbSNP:769902968
1068 1068 a, c dbSNP:748189603
1070 1070 g, t dbSNP:781695328
1084 1084 a, c, t dbSNP:747570345
1089 1089 a, g dbSNP:780536807
1090 1090 a, c, g dbSNP:200510319
1093 1093 a, g dbSNP:748960792
1095 1095 a, c dbSNP:767902038
1100 1100 a, g dbSNP:755588373
1104 1104 c, g dbSNP:748173628
1110 1110 c, g dbSNP:767436357
1111 1111 -, atc dbSNP:774475900
1113 1113 a, c dbSNP:754885393
1119 1119 a, c dbSNP:751536696
1123 1123 c, t dbSNP:766160514
1136 1136 a, g dbSNP:765128439
1142 1142 c, t dbSNP:761907917
1143 1143 a, g dbSNP:776977349
1147 1147 g, t dbSNP:764253958
1153 1153 c, t dbSNP:760847083
1168 1168 c, t dbSNP:776069930
1169 1169 c, t dbSNP:772732812
1181 1181 c, t dbSNP:746199428
1182 1182 a, g dbSNP:574585318
1187 1187 a, g dbSNP:142409152
1189 1189 g, t dbSNP:747753624
1195 1195 -, t dbSNP:769580746
1196 1196 a, g dbSNP:180729483
1198 1198 c, t dbSNP:771168777
1199 1199 a, g dbSNP:72645111
1205 1205 a, g dbSNP:551706206
1208 1208 a, g dbSNP:746527103
1210 1210 a, c dbSNP:779918209
1212 1212 c, t dbSNP:758245407
1219 1219 c, t dbSNP:750414125
1224 1224 a, g dbSNP:72645110
1229 1229 c, t dbSNP:757131301
1233 1233 a, g dbSNP:754052676
1238 1238 c, g dbSNP:781146561
1246 1246 c, t dbSNP:147702347
1247 1247 c, t dbSNP:72645109
1252 1252 a, g dbSNP:375898173
1255 1255 -, g dbSNP:747904876
1262 1262 c, t dbSNP:150033111
1263 1263 a, g dbSNP:372634287
1267 1267 g, t dbSNP:759933475
1279 1279 c, t dbSNP:774991447
1280 1280 c, t dbSNP:771188060
1281 1281 c, t dbSNP:139335335
1282 1282 a, c, g, t dbSNP:201553658
1283 1283 c, t dbSNP:779507200
1287 1287 a, c dbSNP:771678842
1288 1288 c, t dbSNP:745777993
1289 1289 a, g dbSNP:368942111
1290 1290 c, t dbSNP:770607083
1301 1301 c, t dbSNP:749335164
1305 1305 -, c dbSNP:780827736
1316 1316 a, c, t dbSNP:778088118
1326 1326 c, t dbSNP:754948204
1336 1336 c, t dbSNP:751693113
1338 1338 c, t dbSNP:766747041
1340 1340 c, t dbSNP:755217190
1344 1344 c, g dbSNP:750994375
1347 1347 c, t dbSNP:765571538
1352 1352 a, t dbSNP:762177076
1357 1357 a, t dbSNP:764914260
1358 1358 a, t dbSNP:774936628
1359 1359 c, t dbSNP:767227687
1376 1376 a, c dbSNP:758918630
1379 1379 a, g dbSNP:773885589
1393 1393 a, c dbSNP:770392706
1394 1394 g, t dbSNP:749237003
1417 1417 a, g dbSNP:773342959
1419 1419 c, t dbSNP:61731141
1427 1427 c, g dbSNP:779341775
1432 1432 a, t dbSNP:757735280
1438 1438 c, t dbSNP:146177203
1439 1439 a, g dbSNP:778199680
1440 1440 c, t dbSNP:756498521
1441 1441 a, g dbSNP:11542844
1446 1446 a, g dbSNP:766136849
1450 1450 a, g dbSNP:375310967
1451 1451 a, g dbSNP:749978185
1456 1456 g, t dbSNP:764889782
1464 1464 c, g dbSNP:371971622
1476 1476 a, g dbSNP:199671336
1477 1477 a, g dbSNP:768438286
1479 1479 g, t dbSNP:760389728
1488 1488 c, t dbSNP:775647330
1489 1489 c, g, t dbSNP:181065138
1490 1490 a, g, t dbSNP:534158738
1493 1493 c, t dbSNP:139861603
1497 1497 c, g dbSNP:778158546
1500 1500 g, t dbSNP:571599047
1502 1502 a, g dbSNP:753035419
1503 1503 c, t dbSNP:199947703
1504 1504 a, c, g dbSNP:189376498
1505 1505 c, g dbSNP:764826366
1507 1507 c, t dbSNP:761243273
1508 1508 a, g dbSNP:753740830
1514 1514 a, g dbSNP:569195112
1515 1515 a, g dbSNP:149430403
1516 1516 a, c, t dbSNP:767336946
1519 1519 a, g, t dbSNP:375159701
1520 1520 c, t dbSNP:770990050
1547 1547 g, t dbSNP:749335890
1548 1548 c, g dbSNP:369734906
1549 1549 c, t dbSNP:529383103
1550 1550 a, g dbSNP:372873824
1557 1557 c, t dbSNP:567003433
1558 1558 a, g dbSNP:368471914
1565 1565 c, t dbSNP:755461944
1570 1570 a, g dbSNP:193920773
1580 1580 a, g dbSNP:778711245
1589 1589 c, t dbSNP:777289941
1590 1590 a, c dbSNP:769075036
1595 1595 a, g dbSNP:201214012
1601 1601 c, t dbSNP:373986349
1608 1608 c, t dbSNP:756833708
1609 1609 a, g dbSNP:200557019
1614 1614 c, t dbSNP:777139886
1617 1617 c, t dbSNP:72657575
1624 1624 a, g dbSNP:201365745
1625 1625 c, g dbSNP:767449498
1626 1626 a, c, g dbSNP:202151383
1629 1629 a, g dbSNP:754732154
1631 1631 a, g dbSNP:751381592
1638 1638 a, t dbSNP:766246552
1641 1641 a, t dbSNP:763054871
1646 1646 a, c dbSNP:13306616
1656 1656 c, t dbSNP:765219923
1657 1657 a, c, t dbSNP:149484264
1663 1663 c, t dbSNP:769308083
1669 1669 a, g dbSNP:761309529
1681 1681 c, t dbSNP:138011635
1716 1716 g, t dbSNP:768222573
1730 1730 a, g dbSNP:200026546
1733 1733 a, g dbSNP:780056168
1739 1739 a, g dbSNP:758087809
1740 1740 c, t dbSNP:375712066
1741 1741 a, c dbSNP:778899717
1746 1746 -, c dbSNP:758014063
1748 1748 a, c dbSNP:372997123
1751 1751 c, t dbSNP:571384931
1753 1753 a, c, t dbSNP:764254051
1754 1754 a, g dbSNP:551306856
1764 1764 c, t dbSNP:753082199
1765 1765 a, g dbSNP:768103022
1780 1780 -, t dbSNP:754323537
1785 1785 a, g dbSNP:759773949
1786 1786 a, c dbSNP:774758564
1788 1788 g, t dbSNP:766770838
1793 1793 a, g dbSNP:761450468
1802 1802 g, t dbSNP:72657557
1809 1809 c, g dbSNP:771547810
1814 1814 a, g dbSNP:745800866
1831 1831 c, t dbSNP:774440622
1835 1835 c, t dbSNP:369382063
1836 1836 -, ctc dbSNP:764522890
1844 1844 a, t dbSNP:749129164
1848 1848 g, t dbSNP:778094266
1856 1856 g, t dbSNP:756340988
1862 1862 a, g dbSNP:748362963
1867 1867 c, t dbSNP:113622727
1868 1868 a, g dbSNP:72657556
1869 1869 a, g dbSNP:752007565
1876 1876 c, t dbSNP:201873521
1881 1881 c, t dbSNP:146304310
1882 1882 a, g dbSNP:201693951
1884 1884 a, g dbSNP:751095051
1890 1890 -, c dbSNP:756434927
1890 1890 c, t dbSNP:766030532
1893 1893 c, t dbSNP:762984684
1894 1894 c, g dbSNP:773081415
1899 1899 c, t dbSNP:769574907
1903 1903 c, g dbSNP:761519316
1906 1906 a, c, g dbSNP:768842453
1911 1911 c, t dbSNP:747270695
1915 1915 c, t dbSNP:775543049
1916 1916 a, g, t dbSNP:372568407
1918 1918 c, t dbSNP:5742912
1922 1922 c, t dbSNP:757598099
1925 1925 c, t dbSNP:148749888
1926 1926 a, g, t dbSNP:3764873
1927 1927 a, g dbSNP:200923755
1934 1934 c, t dbSNP:765978258
1945 1945 g, t dbSNP:760463562
1946 1946 c, t dbSNP:775589042
1961 1961 c, t dbSNP:148959452
1962 1962 a, g dbSNP:368914240
1963 1963 c, g, t dbSNP:137852634
1964 1964 a, g dbSNP:763359949
1980 1980 c, t dbSNP:138108545
1981 1981 a, g dbSNP:770217992
1989 1989 -, caa dbSNP:753073959
1995 1995 a, g dbSNP:570566104
2000 2000 a, c, g dbSNP:72657550
2004 2004 a, g dbSNP:748814591
2008 2008 a, c dbSNP:777311526
2009 2009 a, g dbSNP:756012753
2020 2020 g, t dbSNP:752700795
2023 2023 -, ttc dbSNP:61759913
2029 2029 c, g dbSNP:780837673
2040 2040 c, t dbSNP:374460984
2042 2042 a, g dbSNP:754815751
2046 2046 c, g dbSNP:751665454
2051 2051 c, t dbSNP:11542843
2069 2069 c, t dbSNP:72657549
2075 2075 c, t dbSNP:757414357
2085 2085 a, g dbSNP:754353092
2088 2088 a, c dbSNP:764684762
2098 2098 a, g dbSNP:761134966
2109 2109 c, g dbSNP:775891291
2115 2115 a, g dbSNP:767835625
2118 2118 c, t dbSNP:762582819
2119 2119 a, g dbSNP:772866436
2126 2126 c, t dbSNP:137852635
2127 2127 a, g dbSNP:199526819
2132 2132 c, t dbSNP:766598472
2134 2134 a, t dbSNP:200443896
2138 2138 c, t dbSNP:768620050
2139 2139 g, t dbSNP:746962921
2147 2147 c, t dbSNP:72657541
2148 2148 a, g dbSNP:779896951
2150 2150 c, g dbSNP:758279404
2157 2157 c, t dbSNP:559461583
2158 2158 a, c, g dbSNP:59142484
2159 2159 c, g, t dbSNP:764120076
2170 2170 a, c dbSNP:756639079
2173 2173 a, g dbSNP:753200672
2174 2174 c, t dbSNP:367983061
2178 2178 c, g dbSNP:759899427
2179 2179 a, g dbSNP:750038511
2180 2180 c, t dbSNP:764895703
2197 2197 c, g dbSNP:761506062
2198 2198 a, g dbSNP:545954539
2202 2202 g, t dbSNP:201759987
2203 2203 g, t dbSNP:760600959
2207 2207 a, g dbSNP:775290860
2212 2212 c, t dbSNP:771949339
2213 2213 a, g dbSNP:140175017
2228 2228 a, g dbSNP:778899652
2230 2230 c, t dbSNP:771246219
2231 2231 a, g, t dbSNP:202038572
2234 2234 a, g dbSNP:756163525
2235 2235 a, g dbSNP:200891555
2237 2237 c, g dbSNP:72657540
2241 2241 a, g dbSNP:781687956
2242 2242 c, g dbSNP:755287192
2246 2246 c, t dbSNP:751903373
2248 2248 c, t dbSNP:766773131
2262 2262 c, t dbSNP:761525147
2277 2277 c, t dbSNP:753494970
2282 2282 -, c dbSNP:773139153
2294 2294 g, t dbSNP:3741913
2295 2295 c, t dbSNP:543479270
2297 2297 a, c, t dbSNP:775445715
2300 2300 -, acc dbSNP:769618870
2307 2307 a, g dbSNP:772108915
2313 2313 a, g dbSNP:574617472
2330 2330 a, g dbSNP:774283066
2334 2334 c, t dbSNP:561526745
2335 2335 c, g dbSNP:749467368
2354 2354 c, t dbSNP:773040403
2355 2355 a, t dbSNP:777865080
2362 2362 a, c dbSNP:769880079
2364 2364 c, t dbSNP:748199518
2366 2366 a, c dbSNP:781302181
2376 2376 c, t dbSNP:370406973
2378 2378 a, c dbSNP:752130523
2381 2381 c, t dbSNP:780386780
2384 2384 a, g dbSNP:758691159
2389 2389 c, t dbSNP:753487231
2390 2390 a, g dbSNP:367681929
2403 2403 a, g dbSNP:573049175
2404 2404 a, g dbSNP:761654238
2407 2407 c, t dbSNP:752223228
2410 2410 a, g dbSNP:767202786
2427 2427 a, c, g, t dbSNP:17846607
2428 2428 a, g, t dbSNP:2228576
2429 2429 c, t dbSNP:762689971
2437 2437 c, t dbSNP:773435718
2439 2439 c, g, t dbSNP:748445983
2441 2441 c, g dbSNP:776691555
2445 2445 -, g dbSNP:776347074
2445 2445 a, g, t dbSNP:539360032
2445 2445 -, g dbSNP:761663786
2446 2446 c, g dbSNP:576872942
2447 2447 c, t dbSNP:780566959
2450 2450 a, g dbSNP:758737621
2455 2455 a, g dbSNP:557017986
2458 2458 a, g dbSNP:779371939
2460 2460 a, g dbSNP:72657539
2464 2464 a, g dbSNP:538153841
2467 2467 g, t dbSNP:767075981
2468 2468 -, t dbSNP:768399005
2476 2476 c, g, t dbSNP:746692672
2489 2489 c, t dbSNP:779629530
2494 2494 a, g dbSNP:370593306
2495 2495 g, t dbSNP:762996681
2498 2498 c, g dbSNP:772855083
2502 2502 a, g dbSNP:377669906
2513 2513 c, t dbSNP:753378218
2514 2514 a, g dbSNP:188694128
2521 2521 c, t dbSNP:72657538
2527 2527 a, g dbSNP:183604895
2552 2552 c, t dbSNP:553848085
2554 2554 c, t dbSNP:566145784
2564 2564 c, t dbSNP:62620999
2585 2585 c, t dbSNP:532711891
2609 2609 c, t dbSNP:188712065
2618 2618 a, g dbSNP:762326102
2655 2655 c, g dbSNP:549794482
2708 2708 a, g dbSNP:374436303
2714 2714 a, g dbSNP:751999385
2747 2747 c, t dbSNP:55981728
2748 2748 a, g dbSNP:370775523
2787 2787 a, g dbSNP:72657537
2800 2800 a, t dbSNP:541167039
2803 2803 a, g dbSNP:72657536
2816 2816 g, t dbSNP:572951397
2850 2850 a, c dbSNP:536027120
2853 2853 c, t dbSNP:559298639
2854 2854 a, g dbSNP:781720164
2874 2874 c, t dbSNP:755355408
2887 2887 c, t dbSNP:751853944
2918 2918 a, c dbSNP:140681881
2943 2943 -, c dbSNP:71450140
2960 2960 g, t dbSNP:150966071
2988 2988 c, t dbSNP:72657535
3002 3002 c, g dbSNP:766654014
3016 3016 c, t dbSNP:72657534
3017 3017 g, t dbSNP:762950321
3039 3039 a, g dbSNP:192846033
3059 3059 c, t dbSNP:750585112
3078 3078 g, t dbSNP:765221861
3083 3083 a, g dbSNP:571203740
3084 3084 g, t dbSNP:62618735
3088 3088 c, t dbSNP:554603722
3154 3154 c, g dbSNP:534430419
3178 3178 a, g dbSNP:549856051
3179 3179 c, t dbSNP:566231983
3216 3216 g, t dbSNP:539591533
3263 3263 a, g dbSNP:72657533
3301 3301 c, t dbSNP:62627411
3320 3320 a, c dbSNP:532769452
3328 3328 c, t dbSNP:776872762
3331 3331 -, t dbSNP:771076540
3365 3365 a, g dbSNP:62619209
3371 3371 c, t dbSNP:72657532
3375 3375 c, t dbSNP:771824185
3398 3398 a, g dbSNP:745491988
3415 3415 a, g dbSNP:72657531
3427 3427 a, g dbSNP:773959273
3439 3439 c, g dbSNP:72657530
3443 3443 c, g dbSNP:777923311
3463 3463 -, tgtt dbSNP:58510764
3463 3463 -, tgtt dbSNP:398088152
3469 3469 -, ttg dbSNP:201016824
3478 3478 a, g dbSNP:547833935

Target ORF information:

RefSeq Version NM_001159576
Organism Homo sapiens (human)
Definition Homo sapiens sodium channel, non voltage gated 1 alpha subunit (SCNN1A), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001159576

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
ATGGGCATGG CCAGGGGCAG CCTCACTCGG GTTCCAGGGG TGATGGGAGA GGGCACTCAG 
GGCCCAGAGC TCAGCCTTGA CCCTGACCCT TGCTCTCCCC AATCCACTCC GGGGCTCATG
AAGGGGAACA AGCTGGAGGA GCAGGACCCT AGACCTCTGC AGCCCATACC AGGTCTCATG
GAGGGGAACA AGCTGGAGGA GCAGGACTCT AGCCCTCCAC AGTCCACTCC AGGGCTCATG
AAGGGGAACA AGCGTGAGGA GCAGGGGCTG GGCCCCGAAC CTGCGGCGCC CCAGCAGCCC
ACGGCGGAGG AGGAGGCCCT GATCGAGTTC CACCGCTCCT ACCGAGAGCT CTTCGAGTTC
TTCTGCAACA ACACCACCAT CCACGGCGCC ATCCGCCTGG TGTGCTCCCA GCACAACCGC
ATGAAGACGG CCTTCTGGGC AGTGCTGTGG CTCTGCACCT TTGGCATGAT GTACTGGCAA
TTCGGCCTGC TTTTCGGAGA GTACTTCAGC TACCCCGTCA GCCTCAACAT CAACCTCAAC
TCGGACAAGC TCGTCTTCCC CGCAGTGACC ATCTGCACCC TCAATCCCTA CAGGTACCCG
GAAATTAAAG AGGAGCTGGA GGAGCTGGAC CGCATCACAG AGCAGACGCT CTTTGACCTG
TACAAATACA GCTCCTTCAC CACTCTCGTG GCCGGCTCCC GCAGCCGTCG CGACCTGCGG
GGGACTCTGC CGCACCCCTT GCAGCGCCTG AGGGTCCCGC CCCCGCCTCA CGGGGCCCGT
CGAGCCCGTA GCGTGGCCTC CAGCTTGCGG GACAACAACC CCCAGGTGGA CTGGAAGGAC
TGGAAGATCG GCTTCCAGCT GTGCAACCAG AACAAATCGG ACTGCTTCTA CCAGACATAC
TCATCAGGGG TGGATGCGGT GAGGGAGTGG TACCGCTTCC ACTACATCAA CATCCTGTCG
AGGCTGCCAG AGACTCTGCC ATCCCTGGAG GAGGACACGC TGGGCAACTT CATCTTCGCC
TGCCGCTTCA ACCAGGTCTC CTGCAACCAG GCGAATTACT CTCACTTCCA CCACCCGATG
TATGGAAACT GCTATACTTT CAATGACAAG AACAACTCCA ACCTCTGGAT GTCTTCCATG
CCTGGAATCA ACAACGGTCT GTCCCTGATG CTGCGCGCAG AGCAGAATGA CTTCATTCCC
CTGCTGTCCA CAGTGACTGG GGCCCGGGTA ATGGTGCACG GGCAGGATGA ACCTGCCTTT
ATGGATGATG GTGGCTTTAA CTTGCGGCCT GGCGTGGAGA CCTCCATCAG CATGAGGAAG
GAAACCCTGG ACAGACTTGG GGGCGATTAT GGCGACTGCA CCAAGAATGG CAGTGATGTT
CCTGTTGAGA ACCTTTACCC TTCAAAGTAC ACACAGCAGG TGTGTATTCA CTCCTGCTTC
CAGGAGAGCA TGATCAAGGA GTGTGGCTGT GCCTACATCT TCTATCCGCG GCCCCAGAAC
GTGGAGTACT GTGACTACAG AAAGCACAGT TCCTGGGGGT ACTGCTACTA TAAGCTCCAG
GTTGACTTCT CCTCAGACCA CCTGGGCTGT TTCACCAAGT GCCGGAAGCC ATGCAGCGTG
ACCAGCTACC AGCTCTCTGC TGGTTACTCA CGATGGCCCT CGGTGACATC CCAGGAATGG
GTCTTCCAGA TGCTATCGCG ACAGAACAAT TACACCGTCA ACAACAAGAG AAATGGAGTG
GCCAAAGTCA ACATCTTCTT CAAGGAGCTG AACTACAAAA CCAATTCTGA GTCTCCCTCT
GTCACGATGG TCACCCTCCT GTCCAACCTG GGCAGCCAGT GGAGCCTGTG GTTCGGCTCC
TCGGTGTTGT CTGTGGTGGA GATGGCTGAG CTCGTCTTTG ACCTGCTGGT CATCATGTTC
CTCATGCTGC TCCGAAGGTT CCGAAGCCGA TACTGGTCTC CAGGCCGAGG GGGCAGGGGT
GCTCAGGAGG TAGCCTCCAC CCTGGCATCC TCCCCTCCTT CCCACTTCTG CCCCCACCCC
ATGTCTCTGT CCTTGTCCCA GCCAGGCCCT GCTCCCTCTC CAGCCTTGAC AGCCCCTCCC
CCTGCCTATG CCACCCTGGG CCCCCGCCCA TCTCCAGGGG GCTCTGCAGG GGCCAGTTCC
TCCACCTGTC CTCTGGGGGG GCCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.