||ORF Nucleotide Sequence (Length: 270bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||C-C motif chemokine 18 precursor
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AC243829.3, BC096124.3 and
On Sep 19, 2014 this sequence version replaced gi:22547150.
Summary: This antimicrobial gene is one of several Cys-Cys (CC)
cytokine genes clustered on the q arm of chromosome 17. Cytokines
are a family of secreted proteins involved in immunoregulatory and
inflammatory processes. The CC cytokines are proteins characterized
by two adjacent cysteines. The cytokine encoded by this gene
displays chemotactic activity for naive T cells, CD4+ and CD8+ T
cells and nonactivated lymphocytes, but not for monocytes or
granulocytes. This chemokine attracts naive T lymphocytes toward
dendritic cells and activated macrophages in lymph nodes. It may
play a role in both humoral and cell-mediated immunity responses.
[provided by RefSeq, Sep 2014].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Protein has antimicrobial activity :: PMID: 12949249
Transcript exon combination :: Y13710.1, AB000221.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: full length.