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SDHD succinate dehydrogenase complex, subunit D, integral membrane protein [Homo sapiens (human)]

Gene Symbol SDHD
Entrez Gene ID 6392
Full Name succinate dehydrogenase complex, subunit D, integral membrane protein
Synonyms CBT1, CII-4, CWS3, PGL, PGL1, QPs3, SDH4, cybS
General protein information
Preferred Names
succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial
Names
succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial
succinate-ubiquinone reductase membrane anchor subunit
succinate-ubiquinone oxidoreductase cytochrome b small subunit
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11q23

Summary This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]. lac of sum
Disorder MIM:

602690

Disorder Html: Paragangliomas, familial nonchromaffin, 1, with or without deafness,





The following SDHD gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SDHD gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu20819 NM_003002 Homo sapiens succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $99
OHu23091 NM_001276503 Homo sapiens succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $99
OHu23016 NM_001276504 Homo sapiens succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $99
OHu20773 NM_001276506 Homo sapiens succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $99

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu20819
Accession Version NM_003002.3
Sequence Information ORF Nucleotide Sequence (Length: 480bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial isoform a precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP002007.4, BQ932668.1, BC015188.1 and AI753083.1. On Feb 23, 2013 this sequence version replaced gi:222352156. Summary: This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]. Transcript Variant: This variant (1) encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta imprinted gene :: PMID: 23291190 ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: BQ932668.1, BC015188.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
ATGGCGGTTC TCTGGAGGCT GAGTGCCGTT TGCGGTGCCC TAGGAGGCCG AGCTCTGTTG 
CTTCGAACTC CAGTGGTCAG ACCTGCTCAT ATCTCAGCAT TTCTTCAGGA CCGACCTATC
CCAGAATGGT GTGGAGTGCA GCACATACAC TTGTCACCGA GCCACCATTC TGGCTCCAAG
GCTGCATCTC TCCACTGGAC TAGCGAGAGG GTTGTCAGTG TTTTGCTCCT GGGTCTGCTT
CCGGCTGCTT ATTTGAATCC TTGCTCTGCG ATGGACTATT CCCTGGCTGC AGCCCTCACT
CTTCATGGTC ACTGGGGCCT TGGACAAGTT GTTACTGACT ATGTTCATGG GGATGCCTTG
CAGAAAGCTG CCAAGGCAGG GCTTTTGGCA CTTTCAGCTT TAACCTTTGC TGGGCTTTGC
TATTTCAACT ATCACGATGT GGGCATCTGC AAAGCTGTTG CCATGCTGTG GAAGCTCTGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_002993.1
CDS85..564
Misc Feature(1)67..69(+)
Misc Feature(2)262..558(+)
Misc Feature(3)262..432(+)
Misc Feature(4)274..339(+)
Misc Feature(5)292..555(+)
Misc Feature(6)331..555(+)
Misc Feature(7)355..417(+)
Misc Feature(8)388..402(+)
Misc Feature(9)424..426(+)
Misc Feature(10)445..510(+)
Exon (1)1..136
Gene:SDHD
Gene Synonym:
Exon (2)137..253
Gene:SDHD
Gene Synonym:
Exon (3)254..398
Gene:SDHD
Gene Synonym:
Exon (4)399..1395
Gene:SDHD
Gene Synonym:
Translation
Position Chain Variation Link
3 3 c, t dbSNP:544421571
4 4 c, g dbSNP:564402774
12 12 c, t dbSNP:752724822
30 30 a, g dbSNP:200665443
34 34 g, t dbSNP:763197227
35 35 c, t dbSNP:202003728
38 38 a, c dbSNP:201097536
45 45 a, g dbSNP:774734438
50 50 g, t dbSNP:200063990
55 55 g, t dbSNP:767806458
58 58 c, g dbSNP:753152376
60 60 a, g dbSNP:200704155
62 62 c, g dbSNP:760995161
64 64 c, g dbSNP:764936238
65 65 c, g dbSNP:372894110
66 66 c, t dbSNP:201382577
70 70 c, g, t dbSNP:757913227
73 73 c, g, t dbSNP:199955367
76 76 a, c dbSNP:780972546
77 77 a, g dbSNP:375890857
81 81 c, t dbSNP:540552714
85 85 a, g, t dbSNP:104894307
87 87 c, g dbSNP:80338842
97 97 c, t dbSNP:778202647
98 98 a, g dbSNP:104894310
100 100 a, g dbSNP:11547889
101 101 a, g dbSNP:770924084
102 102 a, g dbSNP:200895313
107 107 g, t dbSNP:558914063
108 108 c, t dbSNP:11550094
109 109 g, t dbSNP:772671893
117 117 a, c, t dbSNP:104894309
118 118 a, g dbSNP:34677591
119 119 a, g dbSNP:764384503
122 122 c, t dbSNP:750080041
135 135 a, c dbSNP:199890548
137 137 c, t dbSNP:192332761
140 140 c, t dbSNP:574698019
141 141 a, g dbSNP:560625389
141 141 -, g dbSNP:587776649
148 148 c, t dbSNP:104894306
154 154 c, g dbSNP:775986509
164 164 a, g dbSNP:200671534
166 166 c, t dbSNP:541477171
169 169 c, g dbSNP:776930864
172 172 c, t dbSNP:561759202
177 177 c, t dbSNP:766096986
178 178 -, tc dbSNP:397514034
179 179 a, c dbSNP:104894305
185 185 g, t dbSNP:141802836
190 190 c, t dbSNP:104894303
191 191 a, c dbSNP:759143732
192 192 g, t dbSNP:766884646
196 196 c, t dbSNP:80338843
197 197 c, g dbSNP:199901239
200 200 c, g dbSNP:752689382
202 202 a, c, g dbSNP:146276662
205 205 c, t dbSNP:764006625
206 206 c, t dbSNP:753724042
208 208 a, c, g dbSNP:756995021
213 213 a, g dbSNP:104894308
229 229 a, g dbSNP:201949108
232 232 c, t dbSNP:779249550
233 233 a, g dbSNP:11214077
239 239 a, c dbSNP:587782210
242 242 c, t dbSNP:149516118
243 243 a, g dbSNP:201368675
261 261 c, t dbSNP:764869982
264 264 g, t dbSNP:750688879
268 268 a, g dbSNP:758499440
275 275 -, tc dbSNP:387906358
278 278 a, g dbSNP:780226013
288 288 c, t dbSNP:9919552
289 289 a, g dbSNP:202198133
293 293 a, g dbSNP:755047928
298 298 g, t dbSNP:556828083
301 301 a, g dbSNP:748545223
302 302 a, g dbSNP:200486533
312 312 c, t dbSNP:148634289
314 314 c, t dbSNP:777963699
326 326 c, t dbSNP:80338844
327 327 c, g dbSNP:575262156
328 328 c, g, t dbSNP:745559875
331 331 c, g dbSNP:202239399
332 332 c, t dbSNP:370165653
339 339 c, g, t dbSNP:199517389
348 348 c, t dbSNP:761615413
352 352 g, t dbSNP:765102002
353 353 a, c, t dbSNP:200255724
354 354 a, c, g dbSNP:766656463
358 358 g, t dbSNP:80338845
359 359 a, g dbSNP:786205436
360 360 -, tat dbSNP:752036767
361 361 -, tat dbSNP:121908983
362 362 a, g dbSNP:142135772
365 365 c, t dbSNP:199754684
366 366 c, g, t dbSNP:781182616
368 368 c, t dbSNP:80338846
374 374 c, t dbSNP:756533450
377 377 c, t dbSNP:200980609
381 381 c, t dbSNP:749657880
382 382 -, actc dbSNP:786203067
383 383 c, t dbSNP:557454864
388 388 a, c dbSNP:786202403
389 389 a, g, t dbSNP:104894302
394 394 c, g dbSNP:779863605
396 396 c, t dbSNP:61734352
415 415 a, g dbSNP:201869798
419 419 c, t dbSNP:199869408
421 421 -, gact dbSNP:587776648
421 421 -, t dbSNP:587776645
422 422 a, t dbSNP:786202513
425 425 a, g dbSNP:104894304
437 437 a, g dbSNP:750857413
440 440 c, t dbSNP:758784300
443 443 c, t dbSNP:200981457
450 450 a, g dbSNP:780764151
453 453 g, t dbSNP:747779190
470 470 c, t dbSNP:201726097
482 482 a, c dbSNP:755584530
484 484 g, t dbSNP:200851392
494 494 c, t dbSNP:749250498
496 496 a, g dbSNP:786203932
500 500 c, t dbSNP:80338847
506 506 a, g dbSNP:199772639
512 512 a, g dbSNP:770909248
514 514 c, t dbSNP:774243340
515 515 a, t dbSNP:745732631
517 517 a, c dbSNP:121908984
519 519 c, t dbSNP:200062830
522 522 c, t dbSNP:201328474
527 527 -, g dbSNP:587776646
528 528 a, c dbSNP:764099538
532 532 a, t dbSNP:774251278
534 534 c, t dbSNP:201337439
537 537 a, c dbSNP:761953172
547 547 -, a dbSNP:587776647
563 563 g, t dbSNP:201372601
564 564 a, g dbSNP:587778663
565 565 -, ttcata dbSNP:771943101
569 569 c, t dbSNP:201987672
585 585 a, g dbSNP:750950952
587 587 -, ag dbSNP:780035636
591 591 c, t dbSNP:200370142
599 599 a, t dbSNP:201102587
601 601 c, t dbSNP:752323953
602 602 c, g, t dbSNP:200753574
605 605 -, tt dbSNP:746962727
609 609 c, t dbSNP:753390481
612 612 c, g dbSNP:756758340
614 614 a, g dbSNP:778883484
626 626 c, t dbSNP:748029236
657 657 a, t dbSNP:201879236
663 663 c, t dbSNP:200382250
665 665 a, g dbSNP:201057710
672 672 a, g dbSNP:199690207
676 676 a, g dbSNP:200489396
677 677 c, g dbSNP:554448472
697 697 g, t dbSNP:758641993
715 715 a, g dbSNP:201713939
717 717 c, t dbSNP:199510706
745 745 c, t dbSNP:200793705
747 747 c, t dbSNP:201804464
750 750 a, g dbSNP:183918321
770 770 a, g dbSNP:200818209
791 791 a, g dbSNP:541860196
795 795 c, t dbSNP:201662641
815 815 c, g dbSNP:200035181
820 820 a, g dbSNP:201088390
824 824 a, t dbSNP:149570245
826 826 a, g dbSNP:199834076
828 828 a, t dbSNP:201097338
836 836 a, g dbSNP:189227241
849 849 a, t dbSNP:201789478
858 858 a, g dbSNP:200324825
866 866 a, g dbSNP:201163059
876 876 c, g dbSNP:201621566
881 881 c, t dbSNP:200375590
888 888 c, t dbSNP:201475331
894 894 c, t dbSNP:202236414
895 895 a, g dbSNP:200549621
904 904 a, g dbSNP:201280702
916 916 c, g dbSNP:192900956
933 933 a, g dbSNP:200753024
955 955 c, g dbSNP:533163850
959 959 a, c dbSNP:201470807
962 962 a, c dbSNP:540110996
992 992 a, g dbSNP:184654032
1005 1005 c, t dbSNP:200798663
1017 1017 g, t dbSNP:548950317
1034 1034 c, t dbSNP:201695244
1038 1038 c, t dbSNP:200088980
1056 1056 a, g dbSNP:187116888
1067 1067 a, t dbSNP:766039453
1096 1096 a, t dbSNP:146261846
1125 1125 c, t dbSNP:201388681
1126 1126 a, g dbSNP:199954470
1139 1139 c, t dbSNP:200893241
1143 1143 a, g dbSNP:139418464
1149 1149 a, g dbSNP:199841245
1162 1162 a, t dbSNP:201100300
1177 1177 c, t dbSNP:693441
1186 1186 a, g dbSNP:142510105
1212 1212 a, g dbSNP:201560447
1225 1225 a, g dbSNP:201939906
1227 1227 a, g dbSNP:200264243
1229 1229 a, g dbSNP:201421504
1273 1273 a, g dbSNP:199710271
1306 1306 a, g dbSNP:567931768
1311 1311 c, t dbSNP:11214079
1326 1326 a, g dbSNP:191837062
1328 1328 g, t dbSNP:536971023
1330 1330 c, t dbSNP:555396316
1341 1341 a, t dbSNP:183686123
1347 1347 a, t dbSNP:573776592
1363 1363 c, t dbSNP:544286614
1367 1367 a, g dbSNP:17113461
1375 1375 -, c dbSNP:763123482
1386 1386 c, t dbSNP:201472512
1388 1388 a, g dbSNP:764507748

Target ORF information:

RefSeq Version NM_003002
Organism Homo sapiens (human)
Definition Homo sapiens succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003002

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCGGTTC TCTGGAGGCT GAGTGCCGTT TGCGGTGCCC TAGGAGGCCG AGCTCTGTTG 
CTTCGAACTC CAGTGGTCAG ACCTGCTCAT ATCTCAGCAT TTCTTCAGGA CCGACCTATC
CCAGAATGGT GTGGAGTGCA GCACATACAC TTGTCACCGA GCCACCATTC TGGCTCCAAG
GCTGCATCTC TCCACTGGAC TAGCGAGAGG GTTGTCAGTG TTTTGCTCCT GGGTCTGCTT
CCGGCTGCTT ATTTGAATCC TTGCTCTGCG ATGGACTATT CCCTGGCTGC AGCCCTCACT
CTTCATGGTC ACTGGGGCCT TGGACAAGTT GTTACTGACT ATGTTCATGG GGATGCCTTG
CAGAAAGCTG CCAAGGCAGG GCTTTTGGCA CTTTCAGCTT TAACCTTTGC TGGGCTTTGC
TATTTCAACT ATCACGATGT GGGCATCTGC AAAGCTGTTG CCATGCTGTG GAAGCTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23091
Accession Version NM_001276503.1
Sequence Information ORF Nucleotide Sequence (Length: 258bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial isoform b precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP002007.4, BQ932668.1, CD105572.1, BC015188.1 and AI753083.1. Summary: This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]. Transcript Variant: This variant (2) lacks an alternate coding exon, which results in a frameshift, compared to variant 1. The encoded isoform (b) is shorter and has a distinct C-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta imprinted gene :: PMID: 23291190 ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: BG547857.1, BG534514.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
ATGGCGGTTC TCTGGAGGCT GAGTGCCGTT TGCGGTGCCC TAGGAGGCCG AGCTCTGTTG 
CTTCGAACTC CAGTGGTCAG ACCTGCTCAT ATCTCAGCAT TTCTTCAGGA CCGACCTATC
CCAGAATGGT GTGGAGTGCA GCACATACAC TTGTCACCGA GCCACCATTG GGCCTTGGAC
AAGTTGTTAC TGACTATGTT CATGGGGATG CCTTGCAGAA AGCTGCCAAG GCAGGGCTTT
TGGCACTTTC AGCTTTAA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001263432.1
CDS85..342
Misc Feature(1)67..69(+)
Exon (1)1..136
Gene:SDHD
Gene Synonym:
Exon (2)137..253
Gene:SDHD
Gene Synonym:
Exon (3)254..1250
Gene:SDHD
Gene Synonym:
Translation
Position Chain Variation Link
3 3 c, t dbSNP:544421571
4 4 c, g dbSNP:564402774
12 12 c, t dbSNP:752724822
30 30 a, g dbSNP:200665443
34 34 g, t dbSNP:763197227
35 35 c, t dbSNP:202003728
38 38 a, c dbSNP:201097536
45 45 a, g dbSNP:774734438
50 50 g, t dbSNP:200063990
55 55 g, t dbSNP:767806458
58 58 c, g dbSNP:753152376
60 60 a, g dbSNP:200704155
62 62 c, g dbSNP:760995161
64 64 c, g dbSNP:764936238
65 65 c, g dbSNP:372894110
66 66 c, t dbSNP:201382577
70 70 c, g, t dbSNP:757913227
73 73 c, g, t dbSNP:199955367
76 76 a, c dbSNP:780972546
77 77 a, g dbSNP:375890857
81 81 c, t dbSNP:540552714
85 85 a, g, t dbSNP:104894307
87 87 c, g dbSNP:80338842
97 97 c, t dbSNP:778202647
98 98 a, g dbSNP:104894310
100 100 a, g dbSNP:11547889
101 101 a, g dbSNP:770924084
102 102 a, g dbSNP:200895313
107 107 g, t dbSNP:558914063
108 108 c, t dbSNP:11550094
109 109 g, t dbSNP:772671893
117 117 a, c, t dbSNP:104894309
118 118 a, g dbSNP:34677591
119 119 a, g dbSNP:764384503
122 122 c, t dbSNP:750080041
135 135 a, c dbSNP:199890548
137 137 c, t dbSNP:192332761
140 140 c, t dbSNP:574698019
141 141 a, g dbSNP:560625389
141 141 -, g dbSNP:587776649
148 148 c, t dbSNP:104894306
154 154 c, g dbSNP:775986509
164 164 a, g dbSNP:200671534
166 166 c, t dbSNP:541477171
169 169 c, g dbSNP:776930864
172 172 c, t dbSNP:561759202
177 177 c, t dbSNP:766096986
178 178 -, tc dbSNP:397514034
179 179 a, c dbSNP:104894305
185 185 g, t dbSNP:141802836
190 190 c, t dbSNP:104894303
191 191 a, c dbSNP:759143732
192 192 g, t dbSNP:766884646
196 196 c, t dbSNP:80338843
197 197 c, g dbSNP:199901239
200 200 c, g dbSNP:752689382
202 202 a, c, g dbSNP:146276662
205 205 c, t dbSNP:764006625
206 206 c, t dbSNP:753724042
208 208 a, c, g dbSNP:756995021
213 213 a, g dbSNP:104894308
229 229 a, g dbSNP:201949108
232 232 c, t dbSNP:779249550
233 233 a, g dbSNP:11214077
239 239 a, c dbSNP:587782210
242 242 c, t dbSNP:149516118
243 243 a, g dbSNP:201368675
270 270 a, g dbSNP:201869798
274 274 c, t dbSNP:199869408
276 276 -, gact dbSNP:587776648
276 276 -, t dbSNP:587776645
277 277 a, t dbSNP:786202513
280 280 a, g dbSNP:104894304
292 292 a, g dbSNP:750857413
295 295 c, t dbSNP:758784300
298 298 c, t dbSNP:200981457
305 305 a, g dbSNP:780764151
308 308 g, t dbSNP:747779190
325 325 c, t dbSNP:201726097
337 337 a, c dbSNP:755584530
339 339 g, t dbSNP:200851392
349 349 c, t dbSNP:749250498
351 351 a, g dbSNP:786203932
355 355 c, t dbSNP:80338847
361 361 a, g dbSNP:199772639
367 367 a, g dbSNP:770909248
369 369 c, t dbSNP:774243340
370 370 a, t dbSNP:745732631
372 372 a, c dbSNP:121908984
374 374 c, t dbSNP:200062830
377 377 c, t dbSNP:201328474
382 382 -, g dbSNP:587776646
383 383 a, c dbSNP:764099538
387 387 a, t dbSNP:774251278
389 389 c, t dbSNP:201337439
392 392 a, c dbSNP:761953172
402 402 -, a dbSNP:587776647
418 418 g, t dbSNP:201372601
419 419 a, g dbSNP:587778663
420 420 -, ttcata dbSNP:771943101
424 424 c, t dbSNP:201987672
440 440 a, g dbSNP:750950952
442 442 -, ag dbSNP:780035636
446 446 c, t dbSNP:200370142
454 454 a, t dbSNP:201102587
456 456 c, t dbSNP:752323953
457 457 c, g, t dbSNP:200753574
460 460 -, tt dbSNP:746962727
464 464 c, t dbSNP:753390481
467 467 c, g dbSNP:756758340
469 469 a, g dbSNP:778883484
481 481 c, t dbSNP:748029236
512 512 a, t dbSNP:201879236
518 518 c, t dbSNP:200382250
520 520 a, g dbSNP:201057710
527 527 a, g dbSNP:199690207
531 531 a, g dbSNP:200489396
532 532 c, g dbSNP:554448472
552 552 g, t dbSNP:758641993
570 570 a, g dbSNP:201713939
572 572 c, t dbSNP:199510706
600 600 c, t dbSNP:200793705
602 602 c, t dbSNP:201804464
605 605 a, g dbSNP:183918321
625 625 a, g dbSNP:200818209
646 646 a, g dbSNP:541860196
650 650 c, t dbSNP:201662641
670 670 c, g dbSNP:200035181
675 675 a, g dbSNP:201088390
679 679 a, t dbSNP:149570245
681 681 a, g dbSNP:199834076
683 683 a, t dbSNP:201097338
691 691 a, g dbSNP:189227241
704 704 a, t dbSNP:201789478
713 713 a, g dbSNP:200324825
721 721 a, g dbSNP:201163059
731 731 c, g dbSNP:201621566
736 736 c, t dbSNP:200375590
743 743 c, t dbSNP:201475331
749 749 c, t dbSNP:202236414
750 750 a, g dbSNP:200549621
759 759 a, g dbSNP:201280702
771 771 c, g dbSNP:192900956
788 788 a, g dbSNP:200753024
810 810 c, g dbSNP:533163850
814 814 a, c dbSNP:201470807
817 817 a, c dbSNP:540110996
847 847 a, g dbSNP:184654032
860 860 c, t dbSNP:200798663
872 872 g, t dbSNP:548950317
889 889 c, t dbSNP:201695244
893 893 c, t dbSNP:200088980
911 911 a, g dbSNP:187116888
922 922 a, t dbSNP:766039453
951 951 a, t dbSNP:146261846
980 980 c, t dbSNP:201388681
981 981 a, g dbSNP:199954470
994 994 c, t dbSNP:200893241
998 998 a, g dbSNP:139418464
1004 1004 a, g dbSNP:199841245
1017 1017 a, t dbSNP:201100300
1032 1032 c, t dbSNP:693441
1041 1041 a, g dbSNP:142510105
1067 1067 a, g dbSNP:201560447
1080 1080 a, g dbSNP:201939906
1082 1082 a, g dbSNP:200264243
1084 1084 a, g dbSNP:201421504
1128 1128 a, g dbSNP:199710271
1161 1161 a, g dbSNP:567931768
1166 1166 c, t dbSNP:11214079
1181 1181 a, g dbSNP:191837062
1183 1183 g, t dbSNP:536971023
1185 1185 c, t dbSNP:555396316
1196 1196 a, t dbSNP:183686123
1202 1202 a, t dbSNP:573776592
1218 1218 c, t dbSNP:544286614
1222 1222 a, g dbSNP:17113461
1230 1230 -, c dbSNP:763123482
1241 1241 c, t dbSNP:201472512
1243 1243 a, g dbSNP:764507748

Target ORF information:

RefSeq Version NM_001276503
Organism Homo sapiens (human)
Definition Homo sapiens succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001276503

ORF Insert Sequence:

1
61
121
181
241
ATGGCGGTTC TCTGGAGGCT GAGTGCCGTT TGCGGTGCCC TAGGAGGCCG AGCTCTGTTG 
CTTCGAACTC CAGTGGTCAG ACCTGCTCAT ATCTCAGCAT TTCTTCAGGA CCGACCTATC
CCAGAATGGT GTGGAGTGCA GCACATACAC TTGTCACCGA GCCACCATTG GGCCTTGGAC
AAGTTGTTAC TGACTATGTT CATGGGGATG CCTTGCAGAA AGCTGCCAAG GCAGGGCTTT
TGGCACTTTC AGCTTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23016
Accession Version NM_001276504.1
Sequence Information ORF Nucleotide Sequence (Length: 363bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial isoform c precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP002007.4, BQ932668.1, BF211358.1, BC015188.1 and AI753083.1. Summary: This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]. Transcript Variant: This variant (3) lacks an alternate coding exon, but retains the reading frame, compared to variant 1. The encoded isoform (c) is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta imprinted gene :: PMID: 23291190 ##RefSeq-Attributes-END## ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
ATGGCGGTTC TCTGGAGGCT GAGTGCCGTT TGCGGTGCCC TAGGAGGCCG AGCTGGCTCC 
AAGGCTGCAT CTCTCCACTG GACTAGCGAG AGGGTTGTCA GTGTTTTGCT CCTGGGTCTG
CTTCCGGCTG CTTATTTGAA TCCTTGCTCT GCGATGGACT ATTCCCTGGC TGCAGCCCTC
ACTCTTCATG GTCACTGGGG CCTTGGACAA GTTGTTACTG ACTATGTTCA TGGGGATGCC
TTGCAGAAAG CTGCCAAGGC AGGGCTTTTG GCACTTTCAG CTTTAACCTT TGCTGGGCTT
TGCTATTTCA ACTATCACGA TGTGGGCATC TGCAAAGCTG TTGCCATGCT GTGGAAGCTC
TGA
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001263433.1
CDS85..447
Misc Feature(1)67..69(+)
Misc Feature(2)145..441(+)
Misc Feature(3)145..315(+)
Misc Feature(4)175..438(+)
Misc Feature(5)214..438(+)
Misc Feature(6)271..285(+)
Misc Feature(7)307..309(+)
Exon (1)1..136
Gene:SDHD
Gene Synonym:
Exon (2)137..281
Gene:SDHD
Gene Synonym:
Exon (3)282..1278
Gene:SDHD
Gene Synonym:
Translation
Position Chain Variation Link
3 3 c, t dbSNP:544421571
4 4 c, g dbSNP:564402774
12 12 c, t dbSNP:752724822
30 30 a, g dbSNP:200665443
34 34 g, t dbSNP:763197227
35 35 c, t dbSNP:202003728
38 38 a, c dbSNP:201097536
45 45 a, g dbSNP:774734438
50 50 g, t dbSNP:200063990
55 55 g, t dbSNP:767806458
58 58 c, g dbSNP:753152376
60 60 a, g dbSNP:200704155
62 62 c, g dbSNP:760995161
64 64 c, g dbSNP:764936238
65 65 c, g dbSNP:372894110
66 66 c, t dbSNP:201382577
70 70 c, g, t dbSNP:757913227
73 73 c, g, t dbSNP:199955367
76 76 a, c dbSNP:780972546
77 77 a, g dbSNP:375890857
81 81 c, t dbSNP:540552714
85 85 a, g, t dbSNP:104894307
87 87 c, g dbSNP:80338842
97 97 c, t dbSNP:778202647
98 98 a, g dbSNP:104894310
100 100 a, g dbSNP:11547889
101 101 a, g dbSNP:770924084
102 102 a, g dbSNP:200895313
107 107 g, t dbSNP:558914063
108 108 c, t dbSNP:11550094
109 109 g, t dbSNP:772671893
117 117 a, c, t dbSNP:104894309
118 118 a, g dbSNP:34677591
119 119 a, g dbSNP:764384503
122 122 c, t dbSNP:750080041
135 135 a, c dbSNP:199890548
144 144 c, t dbSNP:764869982
147 147 g, t dbSNP:750688879
151 151 a, g dbSNP:758499440
158 158 -, tc dbSNP:387906358
161 161 a, g dbSNP:780226013
171 171 c, t dbSNP:9919552
172 172 a, g dbSNP:202198133
176 176 a, g dbSNP:755047928
181 181 g, t dbSNP:556828083
184 184 a, g dbSNP:748545223
185 185 a, g dbSNP:200486533
195 195 c, t dbSNP:148634289
197 197 c, t dbSNP:777963699
209 209 c, t dbSNP:80338844
210 210 c, g dbSNP:575262156
211 211 c, g, t dbSNP:745559875
214 214 c, g dbSNP:202239399
215 215 c, t dbSNP:370165653
222 222 c, g, t dbSNP:199517389
231 231 c, t dbSNP:761615413
235 235 g, t dbSNP:765102002
236 236 a, c, t dbSNP:200255724
237 237 a, c, g dbSNP:766656463
241 241 g, t dbSNP:80338845
242 242 a, g dbSNP:786205436
243 243 -, tat dbSNP:752036767
244 244 -, tat dbSNP:121908983
245 245 a, g dbSNP:142135772
248 248 c, t dbSNP:199754684
249 249 c, g, t dbSNP:781182616
251 251 c, t dbSNP:80338846
257 257 c, t dbSNP:756533450
260 260 c, t dbSNP:200980609
264 264 c, t dbSNP:749657880
265 265 -, actc dbSNP:786203067
266 266 c, t dbSNP:557454864
271 271 a, c dbSNP:786202403
272 272 a, g, t dbSNP:104894302
277 277 c, g dbSNP:779863605
279 279 c, t dbSNP:61734352
298 298 a, g dbSNP:201869798
302 302 c, t dbSNP:199869408
304 304 -, gact dbSNP:587776648
304 304 -, t dbSNP:587776645
305 305 a, t dbSNP:786202513
308 308 a, g dbSNP:104894304
320 320 a, g dbSNP:750857413
323 323 c, t dbSNP:758784300
326 326 c, t dbSNP:200981457
333 333 a, g dbSNP:780764151
336 336 g, t dbSNP:747779190
353 353 c, t dbSNP:201726097
365 365 a, c dbSNP:755584530
367 367 g, t dbSNP:200851392
377 377 c, t dbSNP:749250498
379 379 a, g dbSNP:786203932
383 383 c, t dbSNP:80338847
389 389 a, g dbSNP:199772639
395 395 a, g dbSNP:770909248
397 397 c, t dbSNP:774243340
398 398 a, t dbSNP:745732631
400 400 a, c dbSNP:121908984
402 402 c, t dbSNP:200062830
405 405 c, t dbSNP:201328474
410 410 -, g dbSNP:587776646
411 411 a, c dbSNP:764099538
415 415 a, t dbSNP:774251278
417 417 c, t dbSNP:201337439
420 420 a, c dbSNP:761953172
430 430 -, a dbSNP:587776647
446 446 g, t dbSNP:201372601
447 447 a, g dbSNP:587778663
448 448 -, ttcata dbSNP:771943101
452 452 c, t dbSNP:201987672
468 468 a, g dbSNP:750950952
470 470 -, ag dbSNP:780035636
474 474 c, t dbSNP:200370142
482 482 a, t dbSNP:201102587
484 484 c, t dbSNP:752323953
485 485 c, g, t dbSNP:200753574
488 488 -, tt dbSNP:746962727
492 492 c, t dbSNP:753390481
495 495 c, g dbSNP:756758340
497 497 a, g dbSNP:778883484
509 509 c, t dbSNP:748029236
540 540 a, t dbSNP:201879236
546 546 c, t dbSNP:200382250
548 548 a, g dbSNP:201057710
555 555 a, g dbSNP:199690207
559 559 a, g dbSNP:200489396
560 560 c, g dbSNP:554448472
580 580 g, t dbSNP:758641993
598 598 a, g dbSNP:201713939
600 600 c, t dbSNP:199510706
628 628 c, t dbSNP:200793705
630 630 c, t dbSNP:201804464
633 633 a, g dbSNP:183918321
653 653 a, g dbSNP:200818209
674 674 a, g dbSNP:541860196
678 678 c, t dbSNP:201662641
698 698 c, g dbSNP:200035181
703 703 a, g dbSNP:201088390
707 707 a, t dbSNP:149570245
709 709 a, g dbSNP:199834076
711 711 a, t dbSNP:201097338
719 719 a, g dbSNP:189227241
732 732 a, t dbSNP:201789478
741 741 a, g dbSNP:200324825
749 749 a, g dbSNP:201163059
759 759 c, g dbSNP:201621566
764 764 c, t dbSNP:200375590
771 771 c, t dbSNP:201475331
777 777 c, t dbSNP:202236414
778 778 a, g dbSNP:200549621
787 787 a, g dbSNP:201280702
799 799 c, g dbSNP:192900956
816 816 a, g dbSNP:200753024
838 838 c, g dbSNP:533163850
842 842 a, c dbSNP:201470807
845 845 a, c dbSNP:540110996
875 875 a, g dbSNP:184654032
888 888 c, t dbSNP:200798663
900 900 g, t dbSNP:548950317
917 917 c, t dbSNP:201695244
921 921 c, t dbSNP:200088980
939 939 a, g dbSNP:187116888
950 950 a, t dbSNP:766039453
979 979 a, t dbSNP:146261846
1008 1008 c, t dbSNP:201388681
1009 1009 a, g dbSNP:199954470
1022 1022 c, t dbSNP:200893241
1026 1026 a, g dbSNP:139418464
1032 1032 a, g dbSNP:199841245
1045 1045 a, t dbSNP:201100300
1060 1060 c, t dbSNP:693441
1069 1069 a, g dbSNP:142510105
1095 1095 a, g dbSNP:201560447
1108 1108 a, g dbSNP:201939906
1110 1110 a, g dbSNP:200264243
1112 1112 a, g dbSNP:201421504
1156 1156 a, g dbSNP:199710271
1189 1189 a, g dbSNP:567931768
1194 1194 c, t dbSNP:11214079
1209 1209 a, g dbSNP:191837062
1211 1211 g, t dbSNP:536971023
1213 1213 c, t dbSNP:555396316
1224 1224 a, t dbSNP:183686123
1230 1230 a, t dbSNP:573776592
1246 1246 c, t dbSNP:544286614
1250 1250 a, g dbSNP:17113461
1258 1258 -, c dbSNP:763123482
1269 1269 c, t dbSNP:201472512
1271 1271 a, g dbSNP:764507748

Target ORF information:

RefSeq Version NM_001276504
Organism Homo sapiens (human)
Definition Homo sapiens succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001276504

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGCGGTTC TCTGGAGGCT GAGTGCCGTT TGCGGTGCCC TAGGAGGCCG AGCTGGCTCC 
AAGGCTGCAT CTCTCCACTG GACTAGCGAG AGGGTTGTCA GTGTTTTGCT CCTGGGTCTG
CTTCCGGCTG CTTATTTGAA TCCTTGCTCT GCGATGGACT ATTCCCTGGC TGCAGCCCTC
ACTCTTCATG GTCACTGGGG CCTTGGACAA GTTGTTACTG ACTATGTTCA TGGGGATGCC
TTGCAGAAAG CTGCCAAGGC AGGGCTTTTG GCACTTTCAG CTTTAACCTT TGCTGGGCTT
TGCTATTTCA ACTATCACGA TGTGGGCATC TGCAAAGCTG TTGCCATGCT GTGGAAGCTC
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu20773
Accession Version NM_001276506.1
Sequence Information ORF Nucleotide Sequence (Length: 432bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial isoform d precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP002007.4, BQ932668.1, BG492859.1, BC015188.1 and AI753083.1. On Oct 19, 2013 this sequence version replaced gi:530398318. Summary: This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]. Transcript Variant: This variant (4) contains an alternate coding exon, which results in a frameshift, compared to variant 1. The encoded isoform (d) is shorter and has a distinct C-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta imprinted gene :: PMID: 23291190 ##RefSeq-Attributes-END## ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
ATGGCGGTTC TCTGGAGGCT GAGTGCCGTT TGCGGTGCCC TAGGAGGCCG AGCTCTGTTG 
CTTCGAACTC CAGTGGTCAG ACCTGCTCAT ATCTCAGCAT TTCTTCAGGA CCGACCTATC
CCAGAATGGT GTGGAGTGCA GCACATACAC TTGTCACCGA GCCACCATTC TGGCTCCAAG
GCTGCATCTC TCCACTGGAC TAGCGAGAGG GTTGTCAGTG TTTTGCTCCT GGGTCTGCTT
CCGGCTGCTT ATTTGAATCC TTGCTCTGCG ATGGACTATT CCCTGGCTGC AGCCCTCACT
CTTCATGGTC ACTGGCTGGA GTGCAATGGT GCGATCTTGG CTCGGCACGA TCTCGGCTCA
GCACGATCTC AGCTTACTGC AACCTCCGCC TTTCGGGTTC AAGCGATTCT CCTGCCTCAG
CCTCCCAAGT AG
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeqNP_001263435.1
CDS85..516
Misc Feature(1)67..69(+)
Misc Feature(2)262..>399(+)
Misc Feature(3)274..339(+)
Misc Feature(4)289..291(+)
Misc Feature(5)310..390(+)
Exon (1)1..136
Gene:SDHD
Gene Synonym:
Exon (2)137..253
Gene:SDHD
Gene Synonym:
Exon (3)254..398
Gene:SDHD
Gene Synonym:
Exon (4)399..528
Gene:SDHD
Gene Synonym:
Exon (5)529..1525
Gene:SDHD
Gene Synonym:
Translation
Position Chain Variation Link
3 3 c, t dbSNP:544421571
4 4 c, g dbSNP:564402774
12 12 c, t dbSNP:752724822
30 30 a, g dbSNP:200665443
34 34 g, t dbSNP:763197227
35 35 c, t dbSNP:202003728
38 38 a, c dbSNP:201097536
45 45 a, g dbSNP:774734438
50 50 g, t dbSNP:200063990
55 55 g, t dbSNP:767806458
58 58 c, g dbSNP:753152376
60 60 a, g dbSNP:200704155
62 62 c, g dbSNP:760995161
64 64 c, g dbSNP:764936238
65 65 c, g dbSNP:372894110
66 66 c, t dbSNP:201382577
70 70 c, g, t dbSNP:757913227
73 73 c, g, t dbSNP:199955367
76 76 a, c dbSNP:780972546
77 77 a, g dbSNP:375890857
81 81 c, t dbSNP:540552714
85 85 a, g, t dbSNP:104894307
87 87 c, g dbSNP:80338842
97 97 c, t dbSNP:778202647
98 98 a, g dbSNP:104894310
100 100 a, g dbSNP:11547889
101 101 a, g dbSNP:770924084
102 102 a, g dbSNP:200895313
107 107 g, t dbSNP:558914063
108 108 c, t dbSNP:11550094
109 109 g, t dbSNP:772671893
117 117 a, c, t dbSNP:104894309
118 118 a, g dbSNP:34677591
119 119 a, g dbSNP:764384503
122 122 c, t dbSNP:750080041
135 135 a, c dbSNP:199890548
137 137 c, t dbSNP:192332761
140 140 c, t dbSNP:574698019
141 141 a, g dbSNP:560625389
141 141 -, g dbSNP:587776649
148 148 c, t dbSNP:104894306
154 154 c, g dbSNP:775986509
164 164 a, g dbSNP:200671534
166 166 c, t dbSNP:541477171
169 169 c, g dbSNP:776930864
172 172 c, t dbSNP:561759202
177 177 c, t dbSNP:766096986
178 178 -, tc dbSNP:397514034
179 179 a, c dbSNP:104894305
185 185 g, t dbSNP:141802836
190 190 c, t dbSNP:104894303
191 191 a, c dbSNP:759143732
192 192 g, t dbSNP:766884646
196 196 c, t dbSNP:80338843
197 197 c, g dbSNP:199901239
200 200 c, g dbSNP:752689382
202 202 a, c, g dbSNP:146276662
205 205 c, t dbSNP:764006625
206 206 c, t dbSNP:753724042
208 208 a, c, g dbSNP:756995021
213 213 a, g dbSNP:104894308
229 229 a, g dbSNP:201949108
232 232 c, t dbSNP:779249550
233 233 a, g dbSNP:11214077
239 239 a, c dbSNP:587782210
242 242 c, t dbSNP:149516118
243 243 a, g dbSNP:201368675
261 261 c, t dbSNP:764869982
264 264 g, t dbSNP:750688879
268 268 a, g dbSNP:758499440
275 275 -, tc dbSNP:387906358
278 278 a, g dbSNP:780226013
288 288 c, t dbSNP:9919552
289 289 a, g dbSNP:202198133
293 293 a, g dbSNP:755047928
298 298 g, t dbSNP:556828083
301 301 a, g dbSNP:748545223
302 302 a, g dbSNP:200486533
312 312 c, t dbSNP:148634289
314 314 c, t dbSNP:777963699
326 326 c, t dbSNP:80338844
327 327 c, g dbSNP:575262156
328 328 c, g, t dbSNP:745559875
331 331 c, g dbSNP:202239399
332 332 c, t dbSNP:370165653
339 339 c, g, t dbSNP:199517389
348 348 c, t dbSNP:761615413
352 352 g, t dbSNP:765102002
353 353 a, c, t dbSNP:200255724
354 354 a, c, g dbSNP:766656463
358 358 g, t dbSNP:80338845
359 359 a, g dbSNP:786205436
360 360 -, tat dbSNP:752036767
361 361 -, tat dbSNP:121908983
362 362 a, g dbSNP:142135772
365 365 c, t dbSNP:199754684
366 366 c, g, t dbSNP:781182616
368 368 c, t dbSNP:80338846
374 374 c, t dbSNP:756533450
377 377 c, t dbSNP:200980609
381 381 c, t dbSNP:749657880
382 382 -, actc dbSNP:786203067
383 383 c, t dbSNP:557454864
388 388 a, c dbSNP:786202403
389 389 a, g, t dbSNP:104894302
394 394 c, g dbSNP:779863605
396 396 c, t dbSNP:61734352
416 416 c, t dbSNP:113458823
419 419 a, t dbSNP:759291000
423 423 -, ggctc dbSNP:569933253
428 428 a, g dbSNP:759717783
432 432 c, t dbSNP:767662911
436 436 c, t dbSNP:752771500
439 439 a, g dbSNP:537332269
441 441 c, t dbSNP:764564009
445 445 a, g dbSNP:2517974
448 448 c, t dbSNP:765022536
449 449 a, g dbSNP:757696980
451 451 -, ctcgg dbSNP:748802699
452 452 c, g dbSNP:779377618
454 454 c, t dbSNP:752411737
455 455 a, g dbSNP:592626
461 461 c, t dbSNP:763929644
471 471 c, t dbSNP:751516982
478 478 c, t dbSNP:111659413
479 479 a, g dbSNP:747677103
488 488 c, t dbSNP:780142529
500 500 c, t dbSNP:186784509
510 510 c, g dbSNP:769335495
545 545 a, g dbSNP:201869798
549 549 c, t dbSNP:199869408
551 551 -, gact dbSNP:587776648
551 551 -, t dbSNP:587776645
552 552 a, t dbSNP:786202513
555 555 a, g dbSNP:104894304
567 567 a, g dbSNP:750857413
570 570 c, t dbSNP:758784300
573 573 c, t dbSNP:200981457
580 580 a, g dbSNP:780764151
583 583 g, t dbSNP:747779190
600 600 c, t dbSNP:201726097
612 612 a, c dbSNP:755584530
614 614 g, t dbSNP:200851392
624 624 c, t dbSNP:749250498
626 626 a, g dbSNP:786203932
630 630 c, t dbSNP:80338847
636 636 a, g dbSNP:199772639
642 642 a, g dbSNP:770909248
644 644 c, t dbSNP:774243340
645 645 a, t dbSNP:745732631
647 647 a, c dbSNP:121908984
649 649 c, t dbSNP:200062830
652 652 c, t dbSNP:201328474
657 657 -, g dbSNP:587776646
658 658 a, c dbSNP:764099538
662 662 a, t dbSNP:774251278
664 664 c, t dbSNP:201337439
667 667 a, c dbSNP:761953172
677 677 -, a dbSNP:587776647
693 693 g, t dbSNP:201372601
694 694 a, g dbSNP:587778663
695 695 -, ttcata dbSNP:771943101
699 699 c, t dbSNP:201987672
715 715 a, g dbSNP:750950952
717 717 -, ag dbSNP:780035636
721 721 c, t dbSNP:200370142
729 729 a, t dbSNP:201102587
731 731 c, t dbSNP:752323953
732 732 c, g, t dbSNP:200753574
735 735 -, tt dbSNP:746962727
739 739 c, t dbSNP:753390481
742 742 c, g dbSNP:756758340
744 744 a, g dbSNP:778883484
756 756 c, t dbSNP:748029236
787 787 a, t dbSNP:201879236
793 793 c, t dbSNP:200382250
795 795 a, g dbSNP:201057710
802 802 a, g dbSNP:199690207
806 806 a, g dbSNP:200489396
807 807 c, g dbSNP:554448472
827 827 g, t dbSNP:758641993
845 845 a, g dbSNP:201713939
847 847 c, t dbSNP:199510706
875 875 c, t dbSNP:200793705
877 877 c, t dbSNP:201804464
880 880 a, g dbSNP:183918321
900 900 a, g dbSNP:200818209
921 921 a, g dbSNP:541860196
925 925 c, t dbSNP:201662641
945 945 c, g dbSNP:200035181
950 950 a, g dbSNP:201088390
954 954 a, t dbSNP:149570245
956 956 a, g dbSNP:199834076
958 958 a, t dbSNP:201097338
966 966 a, g dbSNP:189227241
979 979 a, t dbSNP:201789478
988 988 a, g dbSNP:200324825
996 996 a, g dbSNP:201163059
1006 1006 c, g dbSNP:201621566
1011 1011 c, t dbSNP:200375590
1018 1018 c, t dbSNP:201475331
1024 1024 c, t dbSNP:202236414
1025 1025 a, g dbSNP:200549621
1034 1034 a, g dbSNP:201280702
1046 1046 c, g dbSNP:192900956
1063 1063 a, g dbSNP:200753024
1085 1085 c, g dbSNP:533163850
1089 1089 a, c dbSNP:201470807
1092 1092 a, c dbSNP:540110996
1122 1122 a, g dbSNP:184654032
1135 1135 c, t dbSNP:200798663
1147 1147 g, t dbSNP:548950317
1164 1164 c, t dbSNP:201695244
1168 1168 c, t dbSNP:200088980
1186 1186 a, g dbSNP:187116888
1197 1197 a, t dbSNP:766039453
1226 1226 a, t dbSNP:146261846
1255 1255 c, t dbSNP:201388681
1256 1256 a, g dbSNP:199954470
1269 1269 c, t dbSNP:200893241
1273 1273 a, g dbSNP:139418464
1279 1279 a, g dbSNP:199841245
1292 1292 a, t dbSNP:201100300
1307 1307 c, t dbSNP:693441
1316 1316 a, g dbSNP:142510105
1342 1342 a, g dbSNP:201560447
1355 1355 a, g dbSNP:201939906
1357 1357 a, g dbSNP:200264243
1359 1359 a, g dbSNP:201421504
1403 1403 a, g dbSNP:199710271
1436 1436 a, g dbSNP:567931768
1441 1441 c, t dbSNP:11214079
1456 1456 a, g dbSNP:191837062
1458 1458 g, t dbSNP:536971023
1460 1460 c, t dbSNP:555396316
1471 1471 a, t dbSNP:183686123
1477 1477 a, t dbSNP:573776592
1493 1493 c, t dbSNP:544286614
1497 1497 a, g dbSNP:17113461
1505 1505 -, c dbSNP:763123482
1516 1516 c, t dbSNP:201472512
1518 1518 a, g dbSNP:764507748

Target ORF information:

RefSeq Version NM_001276506
Organism Homo sapiens (human)
Definition Homo sapiens succinate dehydrogenase complex, subunit D, integral membrane protein (SDHD), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001276506

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCGGTTC TCTGGAGGCT GAGTGCCGTT TGCGGTGCCC TAGGAGGCCG AGCTCTGTTG 
CTTCGAACTC CAGTGGTCAG ACCTGCTCAT ATCTCAGCAT TTCTTCAGGA CCGACCTATC
CCAGAATGGT GTGGAGTGCA GCACATACAC TTGTCACCGA GCCACCATTC TGGCTCCAAG
GCTGCATCTC TCCACTGGAC TAGCGAGAGG GTTGTCAGTG TTTTGCTCCT GGGTCTGCTT
CCGGCTGCTT ATTTGAATCC TTGCTCTGCG ATGGACTATT CCCTGGCTGC AGCCCTCACT
CTTCATGGTC ACTGGCTGGA GTGCAATGGT GCGATCTTGG CTCGGCACGA TCTCGGCTCA
GCACGATCTC AGCTTACTGC AACCTCCGCC TTTCGGGTTC AAGCGATTCT CCTGCCTCAG
CCTCCCAAGT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.