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BMP2 cDNA ORF clone, Homo sapiens (human)

Gene Symbol BMP2
Entrez Gene ID 650
Full Name bone morphogenetic protein 2
Synonyms BDA2, BMP2A
General protein information
Preferred Names
bone morphogenetic protein 2
Names
bone morphogenetic protein 2
BMP-2A
bone morphogenetic protein 2A
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

20

20p12

Summary The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

112261

Disorder Html: {HFE hemochromatosis, modifier of}, 235200 (3)

mRNA and Protein(s)

mRNA Protein Name
XM_011529323 XP_011527625 bone morphogenetic protein 2 isoform X1
NM_001200 NP_001191 bone morphogenetic protein 2 preproprotein



Homo sapiens (human) BMP2 NP_001191.1
Pan troglodytes (chimpanzee) BMP2 XP_514508.2
Macaca mulatta (Rhesus monkey) BMP2 XP_001115987.1
Canis lupus familiaris (dog) BMP2 XP_534351.2
Bos taurus (cattle) BMP2 NP_001092611.1
Mus musculus (house mouse) Bmp2 NP_031579.2
Rattus norvegicus (Norway rat) Bmp2 NP_058874.1
Gallus gallus (chicken) BMP2 NP_989689.1
Danio rerio (zebrafish) bmp2a NP_571434.1
Danio rerio (zebrafish) bmp2b NP_571435.1
Drosophila melanogaster (fruit fly) dpp NP_477311.1
Xenopus (Silurana) tropicalis (western clawed frog) bmp2 NP_001015963.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following BMP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the BMP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu56496 XM_011529323 PREDICTED: Homo sapiens bone morphogenetic protein 2 (BMP2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $139.30
$199.00
OHu18169
NM_001200 Homo sapiens bone morphogenetic protein 2 (BMP2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$169.50-$237.30
$339.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu56496
Clone ID Related Accession (Same CDS sequence) XM_011529323
Accession Version XM_011529323.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 723bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product bone morphogenetic protein 2 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011387.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGCAAGATG CTTTAGGAAA CAATAGCAGT TTCCATCACC GAATTAATAT TTATGAAATC 
ATAAAACCTG CAACAGCCAA CTCGAAATTC CCCGTGACCA GACTTTTGGA CACCAGGTTG
GTGAATCAGA ATGCAAGCAG GTGGGAAAGT TTTGATGTCA CCCCCGCTGT GATGCGGTGG
ACTGCACAGG GACACGCCAA CCATGGATTC GTGGTGGAAG TGGCCCACTT GGAGGAGAAA
CAAGGTGTCT CCAAGAGACA TGTTAGGATA AGCAGGTCTT TGCACCAAGA TGAACACAGC
TGGTCACAGA TAAGGCCATT GCTAGTAACT TTTGGCCATG ATGGAAAAGG GCATCCTCTC
CACAAAAGAG AAAAACGTCA AGCCAAACAC AAACAGCGGA AACGCCTTAA GTCCAGCTGT
AAGAGACACC CTTTGTACGT GGACTTCAGT GACGTGGGGT GGAATGACTG GATTGTGGCT
CCCCCGGGGT ATCACGCCTT TTACTGCCAC GGAGAATGCC CTTTTCCTCT GGCTGATCAT
CTGAACTCCA CTAATCATGC CATTGTTCAG ACGTTGGTCA ACTCTGTTAA CTCTAAGATT
CCTAAGGCAT GCTGTGTCCC GACAGAACTC AGTGCTATCT CGATGCTGTA CCTTGACGAG
AATGAAAAGG TTGTATTAAA GAACTATCAG GACATGGTTG TGGAGGGTTG TGGGTGTCGC
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011527625.1
CDS1305..2027
Misc Feature(1)1341..1637(+)
Misc Feature(2)1722..2024(+)
Translation

Target ORF information:

RefSeq Version XM_011529323
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens bone morphogenetic protein 2 (BMP2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011529323

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGCAAGATG CTTTAGGAAA CAATAGCAGT TTCCATCACC GAATTAATAT TTATGAAATC 
ATAAAACCTG CAACAGCCAA CTCGAAATTC CCCGTGACCA GACTTTTGGA CACCAGGTTG
GTGAATCAGA ATGCAAGCAG GTGGGAAAGT TTTGATGTCA CCCCCGCTGT GATGCGGTGG
ACTGCACAGG GACACGCCAA CCATGGATTC GTGGTGGAAG TGGCCCACTT GGAGGAGAAA
CAAGGTGTCT CCAAGAGACA TGTTAGGATA AGCAGGTCTT TGCACCAAGA TGAACACAGC
TGGTCACAGA TAAGGCCATT GCTAGTAACT TTTGGCCATG ATGGAAAAGG GCATCCTCTC
CACAAAAGAG AAAAACGTCA AGCCAAACAC AAACAGCGGA AACGCCTTAA GTCCAGCTGT
AAGAGACACC CTTTGTACGT GGACTTCAGT GACGTGGGGT GGAATGACTG GATTGTGGCT
CCCCCGGGGT ATCACGCCTT TTACTGCCAC GGAGAATGCC CTTTTCCTCT GGCTGATCAT
CTGAACTCCA CTAATCATGC CATTGTTCAG ACGTTGGTCA ACTCTGTTAA CTCTAAGATT
CCTAAGGCAT GCTGTGTCCC GACAGAACTC AGTGCTATCT CGATGCTGTA CCTTGACGAG
AATGAAAAGG TTGTATTAAA GAACTATCAG GACATGGTTG TGGAGGGTTG TGGGTGTCGC
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18169
Clone ID Related Accession (Same CDS sequence) NM_001200
Accession Version NM_001200.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1191bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product bone morphogenetic protein 2 preproprotein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC069214.1, M22489.1 and AL035668.15. This sequence is a reference standard in the RefSeqGene project. On Nov 6, 2005 this sequence version replaced gi:4557368. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC069214.1, M22489.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGGTGGCCG GGACCCGCTG TCTTCTAGCG TTGCTGCTTC CCCAGGTCCT CCTGGGCGGC 
GCGGCTGGCC TCGTTCCGGA GCTGGGCCGC AGGAAGTTCG CGGCGGCGTC GTCGGGCCGC
CCCTCATCCC AGCCCTCTGA CGAGGTCCTG AGCGAGTTCG AGTTGCGGCT GCTCAGCATG
TTCGGCCTGA AACAGAGACC CACCCCCAGC AGGGACGCCG TGGTGCCCCC CTACATGCTA
GACCTGTATC GCAGGCACTC AGGTCAGCCG GGCTCACCCG CCCCAGACCA CCGGTTGGAG
AGGGCAGCCA GCCGAGCCAA CACTGTGCGC AGCTTCCACC ATGAAGAATC TTTGGAAGAA
CTACCAGAAA CGAGTGGGAA AACAACCCGG AGATTCTTCT TTAATTTAAG TTCTATCCCC
ACGGAGGAGT TTATCACCTC AGCAGAGCTT CAGGTTTTCC GAGAACAGAT GCAAGATGCT
TTAGGAAACA ATAGCAGTTT CCATCACCGA ATTAATATTT ATGAAATCAT AAAACCTGCA
ACAGCCAACT CGAAATTCCC CGTGACCAGA CTTTTGGACA CCAGGTTGGT GAATCAGAAT
GCAAGCAGGT GGGAAAGTTT TGATGTCACC CCCGCTGTGA TGCGGTGGAC TGCACAGGGA
CACGCCAACC ATGGATTCGT GGTGGAAGTG GCCCACTTGG AGGAGAAACA AGGTGTCTCC
AAGAGACATG TTAGGATAAG CAGGTCTTTG CACCAAGATG AACACAGCTG GTCACAGATA
AGGCCATTGC TAGTAACTTT TGGCCATGAT GGAAAAGGGC ATCCTCTCCA CAAAAGAGAA
AAACGTCAAG CCAAACACAA ACAGCGGAAA CGCCTTAAGT CCAGCTGTAA GAGACACCCT
TTGTACGTGG ACTTCAGTGA CGTGGGGTGG AATGACTGGA TTGTGGCTCC CCCGGGGTAT
CACGCCTTTT ACTGCCACGG AGAATGCCCT TTTCCTCTGG CTGATCATCT GAACTCCACT
AATCATGCCA TTGTTCAGAC GTTGGTCAAC TCTGTTAACT CTAAGATTCC TAAGGCATGC
TGTGTCCCGA CAGAACTCAG TGCTATCTCG ATGCTGTACC TTGACGAGAA TGAAAAGGTT
GTATTAAAGA ACTATCAGGA CATGGTTGTG GAGGGTTGTG GGTGTCGCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001191.1
CDS786..1976
Misc Feature(1)774..776(+)
Misc Feature(2)909..1586(+)
Misc Feature(3)1671..1973(+)
Exon (1)1..778
Gene:BMP2
Gene Synonym:
Exon (2)779..1131
Gene:BMP2
Gene Synonym:
Exon (3)1132..3150
Gene:BMP2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001200
Organism Homo sapiens (human)
Definition Homo sapiens bone morphogenetic protein 2 (BMP2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001200

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
ATGGTGGCCG GGACCCGCTG TCTTCTAGCG TTGCTGCTTC CCCAGGTCCT CCTGGGCGGC 
GCGGCTGGCC TCGTTCCGGA GCTGGGCCGC AGGAAGTTCG CGGCGGCGTC GTCGGGCCGC
CCCTCATCCC AGCCCTCTGA CGAGGTCCTG AGCGAGTTCG AGTTGCGGCT GCTCAGCATG
TTCGGCCTGA AACAGAGACC CACCCCCAGC AGGGACGCCG TGGTGCCCCC CTACATGCTA
GACCTGTATC GCAGGCACTC AGGTCAGCCG GGCTCACCCG CCCCAGACCA CCGGTTGGAG
AGGGCAGCCA GCCGAGCCAA CACTGTGCGC AGCTTCCACC ATGAAGAATC TTTGGAAGAA
CTACCAGAAA CGAGTGGGAA AACAACCCGG AGATTCTTCT TTAATTTAAG TTCTATCCCC
ACGGAGGAGT TTATCACCTC AGCAGAGCTT CAGGTTTTCC GAGAACAGAT GCAAGATGCT
TTAGGAAACA ATAGCAGTTT CCATCACCGA ATTAATATTT ATGAAATCAT AAAACCTGCA
ACAGCCAACT CGAAATTCCC CGTGACCAGA CTTTTGGACA CCAGGTTGGT GAATCAGAAT
GCAAGCAGGT GGGAAAGTTT TGATGTCACC CCCGCTGTGA TGCGGTGGAC TGCACAGGGA
CACGCCAACC ATGGATTCGT GGTGGAAGTG GCCCACTTGG AGGAGAAACA AGGTGTCTCC
AAGAGACATG TTAGGATAAG CAGGTCTTTG CACCAAGATG AACACAGCTG GTCACAGATA
AGGCCATTGC TAGTAACTTT TGGCCATGAT GGAAAAGGGC ATCCTCTCCA CAAAAGAGAA
AAACGTCAAG CCAAACACAA ACAGCGGAAA CGCCTTAAGT CCAGCTGTAA GAGACACCCT
TTGTACGTGG ACTTCAGTGA CGTGGGGTGG AATGACTGGA TTGTGGCTCC CCCGGGGTAT
CACGCCTTTT ACTGCCACGG AGAATGCCCT TTTCCTCTGG CTGATCATCT GAACTCCACT
AATCATGCCA TTGTTCAGAC GTTGGTCAAC TCTGTTAACT CTAAGATTCC TAAGGCATGC
TGTGTCCCGA CAGAACTCAG TGCTATCTCG ATGCTGTACC TTGACGAGAA TGAAAAGGTT
GTATTAAAGA ACTATCAGGA CATGGTTGTG GAGGGTTGTG GGTGTCGCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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