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PINK1 PTEN induced putative kinase 1 [Homo sapiens (human)]

Gene Symbol PINK1
Entrez Gene ID 65018
Full Name PTEN induced putative kinase 1
Synonyms BRPK, PARK6
General protein information
Preferred Names
serine/threonine-protein kinase PINK1, mitochondrial
Names
serine/threonine-protein kinase PINK1, mitochondrial
protein kinase BRPK
PTEN-induced putative kinase protein 1
NP_115785.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p36

Summary This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

608309

Disorder Html: Parkinson disease 6, early onset, 605909 (3)
CloneID RefSeq Accession Definition **Vector *Turnaround time Price
OHu25380 NM_032409 Homo sapiens PTEN induced putative kinase 1 (PINK1), mRNA. pcDNA3.1-C-(k)DYK In stock -1 Starting from $99.00

*Business Day
**You may select a custom vector to replace pcDNA3.1-C-(k)DYK after clone is added to cart.



CloneID OHu25380D
Sequence Information ORF Nucleotide Sequence (Length: 1746bp)
Protein sequence
SNP
Vector pcDNA3.1-C-(k)DYK or customized vector
Clone information Clone Map
Tag on pcDNA3.1-C-(k)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product serine/threonine-protein kinase PINK1, mitochondrial precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB053323.1 and AL391357.20. This sequence is a reference standard in the RefSeqGene project. On Aug 16, 2006 this sequence version replaced gi:14165271. Summary: This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## ##Evidence-Data-START## Transcript exon combination :: AB053323.1, AF316873.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGGCGGTGC GACAGGCGCT GGGCCGCGGC CTGCAGCTGG GTCGAGCGCT GCTGCTGCGC 
TTCACGGGCA AGCCCGGCCG GGCCTACGGC TTGGGGCGGC CGGGCCCGGC GGCGGGCTGT
GTCCGCGGGG AGCGTCCAGG CTGGGCCGCA GGACCGGGCG CGGAGCCTCG CAGGGTCGGG
CTCGGGCTCC CTAACCGTCT CCGCTTCTTC CGCCAGTCGG TGGCCGGGCT GGCGGCGCGG
TTGCAGCGGC AGTTCGTGGT GCGGGCCTGG GGCTGCGCGG GCCCTTGCGG CCGGGCAGTC
TTTCTGGCCT TCGGGCTAGG GCTGGGCCTC ATCGAGGAAA AACAGGCGGA GAGCCGGCGG
GCGGTCTCGG CCTGTCAGGA GATCCAGGCA ATTTTTACCC AGAAAAGCAA GCCGGGGCCT
GACCCGTTGG ACACGAGACG CTTGCAGGGC TTTCGGCTGG AGGAGTATCT GATAGGGCAG
TCCATTGGTA AGGGCTGCAG TGCTGCTGTG TATGAAGCCA CCATGCCTAC ATTGCCCCAG
AACCTGGAGG TGACAAAGAG CACCGGGTTG CTTCCAGGGA GAGGCCCAGG TACCAGTGCA
CCAGGAGAAG GGCAGGAGCG AGCTCCGGGG GCCCCTGCCT TCCCCTTGGC CATCAAGATG
ATGTGGAACA TCTCGGCAGG TTCCTCCAGC GAAGCCATCT TGAACACAAT GAGCCAGGAG
CTGGTCCCAG CGAGCCGAGT GGCCTTGGCT GGGGAGTATG GAGCAGTCAC TTACAGAAAA
TCCAAGAGAG GTCCCAAGCA ACTAGCCCCT CACCCCAACA TCATCCGGGT TCTCCGCGCC
TTCACCTCTT CCGTGCCGCT GCTGCCAGGG GCCCTGGTCG ACTACCCTGA TGTGCTGCCC
TCACGCCTCC ACCCTGAAGG CCTGGGCCAT GGCCGGACGC TGTTCCTCGT TATGAAGAAC
TATCCCTGTA CCCTGCGCCA GTACCTTTGT GTGAACACAC CCAGCCCCCG CCTCGCCGCC
ATGATGCTGC TGCAGCTGCT GGAAGGCGTG GACCATCTGG TTCAACAGGG CATCGCGCAC
AGAGACCTGA AATCCGACAA CATCCTTGTG GAGCTGGACC CAGACGGCTG CCCCTGGCTG
GTGATCGCAG ATTTTGGCTG CTGCCTGGCT GATGAGAGCA TCGGCCTGCA GTTGCCCTTC
AGCAGCTGGT ACGTGGATCG GGGCGGAAAC GGCTGTCTGA TGGCCCCAGA GGTGTCCACG
GCCCGTCCTG GCCCCAGGGC AGTGATTGAC TACAGCAAGG CTGATGCCTG GGCAGTGGGA
GCCATCGCCT ATGAAATCTT CGGGCTTGTC AATCCCTTCT ACGGCCAGGG CAAGGCCCAC
CTTGAAAGCC GCAGCTACCA AGAGGCTCAG CTACCTGCAC TGCCCGAGTC AGTGCCTCCA
GACGTGAGAC AGTTGGTGAG GGCACTGCTC CAGCGAGAGG CCAGCAAGAG ACCATCTGCC
CGAGTAGCCG CAAATGTGCT TCATCTAAGC CTCTGGGGTG AACATATTCT AGCCCTGAAG
AATCTGAAGT TAGACAAGAT GGTTGGCTGG CTCCTCCAAC AATCGGCCGC CACTTTGTTG
GCCAACAGGC TCACAGAGAA GTGTTGTGTG GAAACAAAAA TGAAGATGCT CTTTCTGGCT
AACCTGGAGT GTGAAACGCT CTGCCAGGCA GCCCTCCTCC TCTGCTCATG GAGGGCAGCC
CTGTGA
The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.
RefSeqNP_115785.1
CDS95..1840
Misc Feature(1)374..424(+)
Misc Feature(2)578..1630(+)
Misc Feature(3)578..1330(+)
Misc Feature(4)578..1246(+)
Misc Feature(5)590..1330(+)
Misc Feature(6)776..778(+)
Misc Feature(7)1241..1330(+)
Misc Feature(8)1298..1300(+)
Exon (1)1..481
Gene:PINK1
Gene Synonym:
Exon (2)482..769
Gene:PINK1
Gene Synonym:
Exon (3)770..870
Gene:PINK1
Gene Synonym:
Exon (4)871..1053
Gene:PINK1
Gene Synonym:
Exon (5)1054..1217
Gene:PINK1
Gene Synonym:
Exon (6)1218..1345
Gene:PINK1
Gene Synonym:
Exon (7)1346..1582
Gene:PINK1
Gene Synonym:
Exon (8)1583..2660
Gene:PINK1
Gene Synonym:
Translation
Position Chain Variation Link
52 52 -, ggcggcagc dbSNP:550535939
161 161 a, g dbSNP:551542832
182 182 c, g dbSNP:569753606
187 187 g, t dbSNP:577010119
208 208 a, g dbSNP:758019868
214 214 g, t dbSNP:780115582
233 233 c, g dbSNP:746940423
239 239 a, g dbSNP:768456559
249 249 c, t dbSNP:776293086
254 254 a, g dbSNP:748343847
259 259 a, g dbSNP:537679886
263 263 -, gcaggg dbSNP:751456355
265 265 c, g dbSNP:555704823
269 269 a, g dbSNP:763000118
270 270 g, t dbSNP:574137009
271 271 c, t dbSNP:766471374
277 277 c, t dbSNP:774802703
278 278 c, g dbSNP:759968468
280 280 a, g dbSNP:767869808
283 283 c, t dbSNP:45530340
290 290 c, t dbSNP:553247784
293 293 c, t dbSNP:763142730
307 307 c, t dbSNP:750146116
310 310 g, t dbSNP:757930144
312 312 c, t dbSNP:202048763
319 319 c, t dbSNP:751445683
320 320 a, g dbSNP:754884141
322 322 a, g dbSNP:781257771
333 333 g, t dbSNP:747865765
339 339 a, c dbSNP:769626575
342 342 a, g dbSNP:544984102
356 356 c, t dbSNP:563467429
360 360 a, c dbSNP:749546463
361 361 c, t dbSNP:770933972
363 363 c, g dbSNP:774312092
365 365 g, t dbSNP:759723977
367 367 -, c dbSNP:755000580
374 374 a, g dbSNP:772448788
381 381 a, g dbSNP:776101618
386 386 c, g, t dbSNP:575668171
394 394 c, t dbSNP:764573020
397 397 c, t dbSNP:750054121
405 405 g, t dbSNP:762698585
408 408 g, t dbSNP:543071128
420 420 a, g dbSNP:751020216
424 424 c, t dbSNP:754557745
427 427 c, t dbSNP:780970528
428 428 c, g dbSNP:752704476
438 438 a, c, t dbSNP:148871409
439 439 c, g dbSNP:749456905
442 442 a, g dbSNP:771132373
453 453 a, g dbSNP:779265931
457 457 g, t dbSNP:745900732
460 460 c, t dbSNP:751529167
462 462 c, g dbSNP:772239179
471 471 a, g dbSNP:775809722
478 478 a, c, t dbSNP:761293056
479 479 c, g dbSNP:777146957
485 485 a, g, t dbSNP:780200003
492 492 c, t dbSNP:374891130
507 507 a, c, g, t dbSNP:781745700
508 508 a, g dbSNP:773637957
511 511 g, t dbSNP:749670160
516 516 a, g dbSNP:369569239
518 518 c, g dbSNP:771748415
519 519 c, g, t dbSNP:775160272
520 520 a, g dbSNP:151146709
523 523 a, g dbSNP:554567650
528 528 c, t dbSNP:45604240
529 529 a, g dbSNP:370346526
532 532 -, a dbSNP:748277653
534 534 a, g dbSNP:138050841
537 537 c, g, t dbSNP:56297806
548 548 c, t dbSNP:45608139
552 552 c, t dbSNP:771094362
555 555 a, g dbSNP:751853691
558 558 a, g dbSNP:755069256
560 560 c, t dbSNP:781425640
566 566 a, g dbSNP:753196052
568 568 a, g dbSNP:374204111
571 571 a, g dbSNP:778207637
573 573 a, c dbSNP:749629580
575 575 c, t dbSNP:771245131
589 589 c, t dbSNP:779637822
591 591 g, t dbSNP:746698825
596 596 c, g dbSNP:768091663
599 599 a, g dbSNP:767633723
604 604 a, g dbSNP:376964979
606 606 a, g dbSNP:776134109
614 614 a, g dbSNP:761290240
621 621 c, t dbSNP:769767842
631 631 c, t dbSNP:773064713
634 634 g, t dbSNP:762760806
637 637 c, t dbSNP:766307462
640 640 a, g dbSNP:751763774
644 644 c, g, t dbSNP:759849441
650 650 a, g dbSNP:371385940
652 652 c, g dbSNP:143204084
655 655 c, t dbSNP:778316508
658 658 c, t dbSNP:754328101
659 659 a, g dbSNP:757581951
661 661 c, g dbSNP:779256340
671 671 a, g dbSNP:543939499
678 678 a, g dbSNP:570488420
680 680 c, t dbSNP:35802484
681 681 c, t dbSNP:138302371
688 688 c, g dbSNP:747663280
690 690 c, g dbSNP:374547622
693 693 c, t dbSNP:149822257
700 700 a, g dbSNP:762803746
708 708 a, g dbSNP:367628601
709 709 a, g dbSNP:368459102
710 710 a, g dbSNP:770790488
713 713 c, t dbSNP:774272854
714 714 a, g dbSNP:759468742
714 714 -, g dbSNP:756677845
719 719 c, g dbSNP:17852513
720 720 c, t dbSNP:34677717
721 721 a, g dbSNP:775620019
725 725 a, g dbSNP:201885172
732 732 a, c dbSNP:764116037
733 733 c, t dbSNP:139649940
738 738 c, g, t dbSNP:371854396
743 743 a, g, t dbSNP:527713210
744 744 a, c dbSNP:74315360
748 748 c, t dbSNP:780875165
752 752 a, g dbSNP:747778265
754 754 a, g dbSNP:755584202
755 755 a, g dbSNP:764042726
759 759 a, g dbSNP:777160388
765 765 c, g, t dbSNP:552625273
768 768 c, t dbSNP:770984783
772 772 a, g dbSNP:200024387
773 773 c, g dbSNP:45545034
774 774 g, t dbSNP:138018628
780 780 c, t dbSNP:777546990
784 784 c, t dbSNP:367947092
785 785 a, g dbSNP:756873821
789 789 c, t dbSNP:144071530
791 791 a, g dbSNP:561948589
795 795 g, t dbSNP:771836537
803 803 a, g dbSNP:775165635
807 807 g, t dbSNP:746882245
812 812 a, g dbSNP:573931674
825 825 c, t dbSNP:776953195
826 826 a, g dbSNP:761861523
830 830 a, c, t dbSNP:74315357
831 831 a, g dbSNP:375601968
833 833 a, g dbSNP:559412676
835 835 a, g dbSNP:149750658
839 839 g, t dbSNP:145650643
846 846 c, g dbSNP:763628949
864 864 c, t dbSNP:370906995
868 868 a, c dbSNP:756783990
869 869 a, t dbSNP:778574505
870 870 a, g dbSNP:750332155
887 887 a, c dbSNP:757969881
889 889 c, t dbSNP:558363399
896 896 c, g dbSNP:372280083
898 898 a, g dbSNP:200708848
900 900 c, t dbSNP:780971409
901 901 c, t dbSNP:747994596
906 906 -, c dbSNP:772688164
907 907 a, c dbSNP:28940284
917 917 a, g dbSNP:544457754
920 920 c, t dbSNP:778009684
921 921 a, g dbSNP:548506734
929 929 c, t dbSNP:61735932
930 930 a, g dbSNP:74315358
931 931 c, t dbSNP:530433531
932 932 a, g dbSNP:772510148
938 938 a, t dbSNP:200036561
940 940 c, g dbSNP:775988170
942 942 c, g dbSNP:761085380
945 945 a, c, t dbSNP:113092523
946 946 c, t dbSNP:368453193
947 947 a, g dbSNP:557503577
951 951 c, t dbSNP:146691996
952 952 a, g dbSNP:148144773
956 956 a, c dbSNP:754928971
958 958 a, g dbSNP:369566143
959 959 a, c dbSNP:777088052
963 963 a, g dbSNP:181675228
970 970 c, g dbSNP:777920274
971 971 c, g dbSNP:749553312
974 974 a, g dbSNP:373473255
981 981 c, t dbSNP:779060308
985 985 c, t dbSNP:745996363
986 986 a, g dbSNP:772706227
996 996 c, t dbSNP:570833319
997 997 a, g dbSNP:776183250
998 998 c, t dbSNP:747359904
999 999 a, g dbSNP:201940147
1007 1007 c, g dbSNP:112600292
1008 1008 c, t dbSNP:7349186
1009 1009 a, t dbSNP:762673179
1015 1015 -, c dbSNP:775975653
1015 1015 c, t dbSNP:200191396
1017 1017 a, t dbSNP:398124659
1020 1020 a, g dbSNP:74315355
1023 1023 a, g dbSNP:375197494
1025 1025 a, g dbSNP:773906022
1028 1028 c, t dbSNP:536146282
1029 1029 a, g dbSNP:202128685
1030 1030 a, g dbSNP:56200357
1032 1032 c, t dbSNP:74315359
1033 1033 a, g dbSNP:142866598
1036 1036 a, g dbSNP:145990823
1042 1042 c, t dbSNP:142183624
1043 1043 a, g dbSNP:200949139
1046 1046 a, t dbSNP:139226733
1048 1048 -, gaa dbSNP:761346571
1056 1056 a, g dbSNP:755060576
1059 1059 c, t dbSNP:768019187
1060 1060 c, g dbSNP:199678436
1062 1062 a, g dbSNP:373417787
1063 1063 a, t dbSNP:778010106
1070 1070 c, t dbSNP:376323248
1071 1071 a, g, t dbSNP:142028165
1072 1072 c, t dbSNP:746502670
1097 1097 a, g dbSNP:144330127
1099 1099 c, t dbSNP:776594592
1103 1103 c, t dbSNP:748041977
1104 1104 a, g dbSNP:184043309
1105 1105 c, t dbSNP:149187537
1108 1108 c, t dbSNP:762909782
1109 1109 a, g dbSNP:55831733
1112 1112 a, g dbSNP:3738136
1112 1112 -, g dbSNP:752683079
1115 1115 a, g dbSNP:759620550
1117 1117 a, g dbSNP:35813094
1118 1118 a, c dbSNP:753186891
1129 1129 g, t dbSNP:201920474
1134 1134 c, t dbSNP:28940285
1142 1142 a, c, g dbSNP:764648391
1145 1145 a, g dbSNP:757669987
1154 1154 g, t dbSNP:779637743
1159 1159 a, g dbSNP:370470902
1161 1161 -, ag dbSNP:756183137
1169 1169 a, g dbSNP:76753586
1170 1170 c, t dbSNP:780580396
1171 1171 a, g dbSNP:144550985
1172 1172 -, ca dbSNP:764252130
1189 1189 c, t dbSNP:559921009
1190 1190 a, g dbSNP:200729715
1192 1192 c, t dbSNP:773330518
1194 1194 a, g, t dbSNP:749040285
1197 1197 a, t dbSNP:774647122
1199 1199 c, t dbSNP:759686620
1210 1210 -, ggaccc dbSNP:754024208
1217 1217 c, g dbSNP:767833301
1219 1219 c, t dbSNP:531300037
1224 1224 g, t dbSNP:34203620
1234 1234 a, g dbSNP:55962214
1238 1238 a, g dbSNP:768758677
1239 1239 g, t dbSNP:777060019
1240 1240 a, c, t dbSNP:548701521
1241 1241 a, g dbSNP:45515602
1247 1247 c, t dbSNP:763416852
1253 1253 g, t dbSNP:200462866
1258 1258 c, t dbSNP:752424503
1261 1261 a, g dbSNP:534505756
1267 1267 c, t dbSNP:45499398
1268 1268 -, ga dbSNP:780474701
1270 1270 c, g dbSNP:777439010
1272 1272 c, g dbSNP:368939214
1274 1274 a, g dbSNP:757253324
1276 1276 c, t dbSNP:373528661
1280 1280 c, t dbSNP:368216507
1283 1283 c, t dbSNP:139094526
1290 1290 c, t dbSNP:119451946
1294 1294 c, t dbSNP:780102678
1299 1299 a, g dbSNP:200728364
1306 1306 c, t dbSNP:747239996
1307 1307 a, g dbSNP:145821082
1309 1309 a, g dbSNP:776679219
1313 1313 c, t dbSNP:145876364
1314 1314 a, g, t dbSNP:556540177
1318 1318 c, t dbSNP:763185637
1319 1319 a, g dbSNP:574890623
1324 1324 c, t dbSNP:774946874
1325 1325 a, g dbSNP:45478900
1330 1330 g, t dbSNP:374657174
1331 1331 c, g dbSNP:202130946
1332 1332 c, t dbSNP:573411900
1346 1346 a, c, g dbSNP:777895210
1350 1350 c, t dbSNP:771433825
1352 1352 a, g dbSNP:775043563
1354 1354 a, g dbSNP:746182917
1356 1356 c, t dbSNP:772593766
1357 1357 c, t dbSNP:776359607
1358 1358 c, t dbSNP:374167096
1359 1359 a, g dbSNP:201491485
1364 1364 c, g dbSNP:769395168
1365 1365 a, g dbSNP:772774256
1367 1367 c, t dbSNP:554114655
1370 1370 a, t dbSNP:766319968
1373 1373 a, g dbSNP:751522476
1376 1376 -, gagaa dbSNP:759184946
1381 1381 c, t dbSNP:759257778
1385 1385 c, t dbSNP:74315361
1389 1389 a, g dbSNP:368438636
1393 1393 a, g dbSNP:371775590
1394 1394 a, g dbSNP:374910091
1399 1399 c, t dbSNP:756355011
1401 1401 a, c dbSNP:777892391
1405 1405 a, g dbSNP:74315356
1407 1407 c, t dbSNP:183454580
1413 1413 a, g dbSNP:45467995
1415 1415 -, gc dbSNP:767413204
1415 1415 a, g dbSNP:369043567
1421 1421 a, g dbSNP:148313557
1422 1422 -, c dbSNP:775479526
1422 1422 c, t dbSNP:138135040
1425 1425 a, g dbSNP:143659957
1435 1435 c, t dbSNP:140652495
1436 1436 a, g dbSNP:751275626
1446 1446 a, g dbSNP:747400197
1455 1455 a, g dbSNP:769460438
1456 1456 c, t dbSNP:56383368
1459 1459 c, g dbSNP:369112191
1460 1460 c, t dbSNP:45539432
1461 1461 a, g dbSNP:150964528
1465 1465 c, g dbSNP:199705273
1474 1474 c, t dbSNP:369755617
1476 1476 g, t dbSNP:144440543
1477 1477 c, t dbSNP:752502090
1481 1481 a, g dbSNP:760436322
1485 1485 a, g dbSNP:764328076
1493 1493 c, g dbSNP:373657922
1494 1494 a, c dbSNP:757292901
1509 1509 c, t dbSNP:779148944
1512 1512 c, t dbSNP:750589610
1513 1513 a, g dbSNP:544964252
1519 1519 c, t dbSNP:150183401
1520 1520 a, g dbSNP:115477764
1523 1523 a, t dbSNP:34416410
1526 1526 a, g dbSNP:777444688
1527 1527 c, t dbSNP:748904588
1536 1536 a, t dbSNP:376829940
1537 1537 c, t dbSNP:770625275
1538 1538 a, g, t dbSNP:773843241
1540 1540 c, g dbSNP:771974605
1545 1545 -, agtt dbSNP:760671205
1552 1552 a, g dbSNP:775311318
1568 1568 c, t dbSNP:34208370
1569 1569 a, g dbSNP:143620063
1573 1573 a, g dbSNP:756630437
1575 1575 c, t dbSNP:542258150
1582 1582 a, g dbSNP:56217826
1586 1586 -, cat dbSNP:757382757
1596 1596 a, g dbSNP:61744200
1597 1597 a, g dbSNP:757843763
1598 1598 a, g dbSNP:779418622
1600 1600 a, g dbSNP:746598031
1603 1603 c, t dbSNP:768447159
1604 1604 a, g dbSNP:779294259
1605 1605 c, t dbSNP:560377198
1606 1606 a, c dbSNP:527565484
1608 1608 a, t dbSNP:773504394
1610 1610 a, g dbSNP:763284341
1624 1624 c, t dbSNP:367949045
1629 1629 a, c, g dbSNP:774261081
1638 1638 a, g dbSNP:141363209
1643 1643 c, t dbSNP:149466252
1648 1648 c, t dbSNP:760962342
1651 1651 -, g dbSNP:765320312
1654 1654 a, g dbSNP:764454206
1656 1656 a, c dbSNP:1043424
1667 1667 -, ttag dbSNP:730880302
1667 1667 a, g dbSNP:531477772
1670 1670 a, g dbSNP:371338035
1673 1673 a, g dbSNP:779798626
1674 1674 c, t dbSNP:751012180
1677 1677 c, t dbSNP:754543494
1687 1687 c, t dbSNP:780954418
1690 1690 -, caa dbSNP:750664040
1695 1695 a, c dbSNP:748103970
1698 1698 c, t dbSNP:146126901
1699 1699 a, g dbSNP:149070918
1702 1702 c, t dbSNP:749131400
1703 1703 a, g dbSNP:771032673
1715 1715 g, t dbSNP:61749520
1719 1719 a, c dbSNP:536023801
1725 1725 c, t dbSNP:554043854
1726 1726 c, t dbSNP:566377750
1731 1731 -, gaagt dbSNP:758615369
1731 1731 a, g dbSNP:761156393
1734 1734 a, c dbSNP:764654160
1741 1741 c, t dbSNP:754173479
1748 1748 a, g dbSNP:762287023
1763 1763 c, t dbSNP:765900048
1764 1764 g, t dbSNP:751259577
1765 1765 c, t dbSNP:754383296
1781 1781 g, t dbSNP:780865659
1783 1783 a, g dbSNP:752317048
1785 1785 c, g dbSNP:756084756
1791 1791 c, t dbSNP:777903263
1792 1792 a, g dbSNP:777232150
1810 1810 c, t dbSNP:778039430
1812 1812 c, t dbSNP:757102843
1813 1813 c, t dbSNP:201936304
1815 1815 c, t dbSNP:746115592
1818 1818 c, g dbSNP:772238634
1822 1822 a, g dbSNP:149994404
1823 1823 c, t dbSNP:747133533
1828 1828 g, t dbSNP:769130824
1830 1830 a, c dbSNP:777145627
1833 1833 c, t dbSNP:762044569
1839 1839 a, g, t dbSNP:765643910
1842 1842 a, g dbSNP:557733185
1844 1844 c, t dbSNP:759215944
1845 1845 c, t dbSNP:767315202
1848 1848 a, g dbSNP:752229600
1849 1849 c, t dbSNP:200804593
1852 1852 a, g dbSNP:764080257
1858 1858 a, g dbSNP:369117599
1867 1867 c, t dbSNP:756943990
1869 1869 -, aaag dbSNP:780383135
1870 1870 -, aag dbSNP:751960578
1870 1870 a, g dbSNP:778753937
1873 1873 g, t dbSNP:745716449
1876 1876 c, g dbSNP:758589344
1877 1877 a, t dbSNP:686658
1880 1880 a, g dbSNP:115768147
1894 1894 a, g dbSNP:142119718
1930 1930 a, g dbSNP:574322103
1940 1940 c, t dbSNP:542031461
1961 1961 a, g dbSNP:570308715
1968 1968 a, g dbSNP:560057726
1980 1980 a, g dbSNP:527584809
1996 1996 a, g dbSNP:545773867
2019 2019 c, t dbSNP:11554543
2021 2021 c, g dbSNP:513414
2025 2025 c, t dbSNP:531314951
2036 2036 c, t dbSNP:1043443
2057 2057 c, g dbSNP:747898400
2072 2072 a, g dbSNP:770274050
2105 2105 c, g, t dbSNP:512550
2108 2108 a, t dbSNP:2320395
2141 2141 a, g dbSNP:528947798
2162 2162 c, t dbSNP:773053961
2189 2189 c, g dbSNP:114112086
2196 2196 c, t dbSNP:760235785
2203 2203 c, t dbSNP:766026420
2235 2235 a, t dbSNP:372830163
2248 2248 c, g dbSNP:566095746
2255 2255 c, g dbSNP:8064
2259 2259 -, a dbSNP:538929443
2262 2262 a, g dbSNP:551649705
2269 2269 g, t dbSNP:147759776
2326 2326 a, c dbSNP:369053717
2330 2330 a, c dbSNP:16824318
2335 2335 c, t dbSNP:555315482
2349 2349 c, t dbSNP:574097463
2358 2358 c, t dbSNP:765673394
2366 2366 -, agta dbSNP:566389012
2367 2367 -, agta dbSNP:138181538
2372 2372 a, g dbSNP:190393061
2374 2374 a, g dbSNP:553977557
2381 2381 -, aagt dbSNP:3077906
2385 2385 a, g dbSNP:193299196
2387 2387 a, g dbSNP:546151634
2404 2404 g, t dbSNP:1043502
2407 2407 c, g dbSNP:11554544
2410 2410 -, ctga dbSNP:143763511
2410 2410 -, c dbSNP:556390159
2416 2416 -, gact dbSNP:375956041
2426 2426 c, t dbSNP:184877436
2444 2444 c, t dbSNP:543456950
2465 2465 c, t dbSNP:558718255
2467 2467 a, g dbSNP:112126165
2495 2495 c, t dbSNP:141140099
2510 2510 -, ttc dbSNP:33999970
2512 2512 c, t dbSNP:2078073
2512 2512 c, tctt dbSNP:67252247
2513 2513 -, ctt, t dbSNP:71760582
2515 2515 -, ctt dbSNP:3077908
2557 2557 c, t dbSNP:181532922
2562 2562 -, aag dbSNP:34119921
2563 2563 -, agag, g dbSNP:34361349
2564 2564 -, gaga dbSNP:3077910
2568 2568 -, gaga dbSNP:398069438
2569 2569 a, t dbSNP:559936998
2574 2574 c, t dbSNP:533348669
2576 2576 -, ctaa dbSNP:113674347
2577 2577 -, ctaa dbSNP:758797319
2577 2577 a, c dbSNP:185791919
2581 2581 c, t dbSNP:752692312
2590 2590 -, aact dbSNP:372726829
2629 2629 a, g dbSNP:570038599
2631 2631 c, g dbSNP:537315041
2647 2647 c, t dbSNP:78349864
2651 2651 c, t dbSNP:567546379

Target ORF information:

RefSeq Version NM_032409
Organism Homo sapiens (human)
Definition Homo sapiens PTEN induced putative kinase 1 (PINK1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1-C-(k)DYK
NM_032409

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
ATGGCGGTGC GACAGGCGCT GGGCCGCGGC CTGCAGCTGG GTCGAGCGCT GCTGCTGCGC 
TTCACGGGCA AGCCCGGCCG GGCCTACGGC TTGGGGCGGC CGGGCCCGGC GGCGGGCTGT
GTCCGCGGGG AGCGTCCAGG CTGGGCCGCA GGACCGGGCG CGGAGCCTCG CAGGGTCGGG
CTCGGGCTCC CTAACCGTCT CCGCTTCTTC CGCCAGTCGG TGGCCGGGCT GGCGGCGCGG
TTGCAGCGGC AGTTCGTGGT GCGGGCCTGG GGCTGCGCGG GCCCTTGCGG CCGGGCAGTC
TTTCTGGCCT TCGGGCTAGG GCTGGGCCTC ATCGAGGAAA AACAGGCGGA GAGCCGGCGG
GCGGTCTCGG CCTGTCAGGA GATCCAGGCA ATTTTTACCC AGAAAAGCAA GCCGGGGCCT
GACCCGTTGG ACACGAGACG CTTGCAGGGC TTTCGGCTGG AGGAGTATCT GATAGGGCAG
TCCATTGGTA AGGGCTGCAG TGCTGCTGTG TATGAAGCCA CCATGCCTAC ATTGCCCCAG
AACCTGGAGG TGACAAAGAG CACCGGGTTG CTTCCAGGGA GAGGCCCAGG TACCAGTGCA
CCAGGAGAAG GGCAGGAGCG AGCTCCGGGG GCCCCTGCCT TCCCCTTGGC CATCAAGATG
ATGTGGAACA TCTCGGCAGG TTCCTCCAGC GAAGCCATCT TGAACACAAT GAGCCAGGAG
CTGGTCCCAG CGAGCCGAGT GGCCTTGGCT GGGGAGTATG GAGCAGTCAC TTACAGAAAA
TCCAAGAGAG GTCCCAAGCA ACTAGCCCCT CACCCCAACA TCATCCGGGT TCTCCGCGCC
TTCACCTCTT CCGTGCCGCT GCTGCCAGGG GCCCTGGTCG ACTACCCTGA TGTGCTGCCC
TCACGCCTCC ACCCTGAAGG CCTGGGCCAT GGCCGGACGC TGTTCCTCGT TATGAAGAAC
TATCCCTGTA CCCTGCGCCA GTACCTTTGT GTGAACACAC CCAGCCCCCG CCTCGCCGCC
ATGATGCTGC TGCAGCTGCT GGAAGGCGTG GACCATCTGG TTCAACAGGG CATCGCGCAC
AGAGACCTGA AATCCGACAA CATCCTTGTG GAGCTGGACC CAGACGGCTG CCCCTGGCTG
GTGATCGCAG ATTTTGGCTG CTGCCTGGCT GATGAGAGCA TCGGCCTGCA GTTGCCCTTC
AGCAGCTGGT ACGTGGATCG GGGCGGAAAC GGCTGTCTGA TGGCCCCAGA GGTGTCCACG
GCCCGTCCTG GCCCCAGGGC AGTGATTGAC TACAGCAAGG CTGATGCCTG GGCAGTGGGA
GCCATCGCCT ATGAAATCTT CGGGCTTGTC AATCCCTTCT ACGGCCAGGG CAAGGCCCAC
CTTGAAAGCC GCAGCTACCA AGAGGCTCAG CTACCTGCAC TGCCCGAGTC AGTGCCTCCA
GACGTGAGAC AGTTGGTGAG GGCACTGCTC CAGCGAGAGG CCAGCAAGAG ACCATCTGCC
CGAGTAGCCG CAAATGTGCT TCATCTAAGC CTCTGGGGTG AACATATTCT AGCCCTGAAG
AATCTGAAGT TAGACAAGAT GGTTGGCTGG CTCCTCCAAC AATCGGCCGC CACTTTGTTG
GCCAACAGGC TCACAGAGAA GTGTTGTGTG GAAACAAAAA TGAAGATGCT CTTTCTGGCT
AACCTGGAGT GTGAAACGCT CTGCCAGGCA GCCCTCCTCC TCTGCTCATG GAGGGCAGCC
CTGTGA

The stop codons will be deleted if pcDNA3.1-C-(k)DYK vector is selected.