The following SLC2A4 gene sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC2A4 gene which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
||ORF Nucleotide Sequence (Length: 1530bp)
||pcDNA3.1+/C-(K)DYK or customized vector
|Tag on pcDNA3.1+/C-(K)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||solute carrier family 2, facilitated glucose transporter member 4
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from CF594356.1, M20747.1,
BC034387.1, AL521328.3, AC003688.1 and BQ775137.1.
This sequence is a reference standard in the RefSeqGene project.
On Dec 19, 2005 this sequence version replaced gi:4507010.
Summary: This gene is a member of the solute carrier family 2
(facilitated glucose transporter) family and encodes a protein that
functions as an insulin-regulated facilitative glucose transporter.
In the absence of insulin, this integral membrane protein is
sequestered within the cells of muscle and adipose tissue. Within
minutes of insulin stimulation, the protein moves to the cell
surface and begins to transport glucose across the cell membrane.
Mutations in this gene have been associated with
noninsulin-dependent diabetes mellitus (NIDDM). [provided by
RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: M20747.1, AK313372.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
COMPLETENESS: complete on the 3' end.