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SNAI2 cDNA ORF clone, Homo sapiens (human)

Gene Symbol SNAI2
Entrez Gene ID 6591
Full Name snail family zinc finger 2
Synonyms SLUG, SLUGH1, SNAIL2, WS2D
General protein information
Preferred Names
zinc finger protein SNAI2
Names
zinc finger protein SNAI2
snail homolog 2
protein snail homolog 2
neural crest transcription factor SLUG
slug (chicken homolog), zinc finger protein
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

8

8q11

Summary This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

602150

Disorder Html: Waardenburg syndrome, type 2D, 608890 (3); Piebaldism, 172800 (3)





The following SNAI2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SNAI2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu22833 NM_003068 Homo sapiens snail family zinc finger 2 (SNAI2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$216.30
$309.00

*Business Day
**You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.


CloneID OHu22833
Accession Version NM_003068.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 807bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product zinc finger protein SNAI2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA522147.1, BC015895.1 and AC013701.6. This sequence is a reference standard in the RefSeqGene project. On Feb 25, 2011 this sequence version replaced gi:24497625. Summary: This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK223368.1, BC014890.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962337, SAMEA962343 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGCCGCGCT CCTTCCTGGT CAAGAAGCAT TTCAACGCCT CCAAAAAGCC AAACTACAGC 
GAACTGGACA CACATACAGT GATTATTTCC CCGTATCTCT ATGAGAGTTA CTCCATGCCT
GTCATACCAC AACCAGAGAT CCTCAGCTCA GGAGCATACA GCCCCATCAC TGTGTGGACT
ACCGCTGCTC CATTCCACGC CCAGCTACCC AATGGCCTCT CTCCTCTTTC CGGATACTCC
TCATCTTTGG GGCGAGTGAG TCCCCCTCCT CCATCTGACA CCTCCTCCAA GGACCACAGT
GGCTCAGAAA GCCCCATTAG TGATGAAGAG GAAAGACTAC AGTCCAAGCT TTCAGACCCC
CATGCCATTG AAGCTGAAAA GTTTCAGTGC AATTTATGCA ATAAGACCTA TTCAACTTTT
TCTGGGCTGG CCAAACATAA GCAGCTGCAC TGCGATGCCC AGTCTAGAAA ATCTTTCAGC
TGTAAATACT GTGACAAGGA ATATGTGAGC CTGGGCGCCC TGAAGATGCA TATTCGGACC
CACACATTAC CTTGTGTTTG CAAGATCTGC GGCAAGGCGT TTTCCAGACC CTGGTTGCTT
CAAGGACACA TTAGAACTCA CACGGGGGAG AAGCCTTTTT CTTGCCCTCA CTGCAACAGA
GCATTTGCAG ACAGGTCAAA TCTGAGGGCT CATCTGCAGA CCCATTCTGA TGTAAAGAAA
TACCAGTGCA AAAACTGCTC CAAAACCTTC TCCAGAATGT CTCTCCTGCA CAAACATGAG
GAATCTGGCT GCTGTGTAGC ACACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeqNP_003059.1
CDS176..982
Misc Feature(1)68..70(+)
Misc Feature(2)176..235(+)
Misc Feature(3)563..625(+)
Misc Feature(4)563..625(+)
Misc Feature(5)578..715(+)
Misc Feature(6)656..718(+)
Misc Feature(7)656..718(+)
Misc Feature(8)656..718(+)
Misc Feature(9)656..718(+)
Misc Feature(10)671..793(+)
Misc Feature(11)719..>949(+)
Misc Feature(12)734..796(+)
Misc Feature(13)734..796(+)
Misc Feature(14)734..796(+)
Misc Feature(15)734..796(+)
Misc Feature(16)749..952(+)
Misc Feature(17)773..844(+)
Misc Feature(18)818..880(+)
Misc Feature(19)818..877(+)
Misc Feature(20)854..931(+)
Misc Feature(21)902..952(+)
Misc Feature(22)902..952(+)
Exon (1)1..254
Gene:SNAI2
Gene Synonym:
Exon (2)255..800
Gene:SNAI2
Gene Synonym:
Exon (3)801..2112
Gene:SNAI2
Gene Synonym:
Translation
Position Chain Variation Link
7 7 c, g dbSNP:369985957
13 13 a, g dbSNP:189960900
17 17 c, g dbSNP:139228799
30 30 g, t dbSNP:575616515
55 55 c, t dbSNP:377272066
74 74 a, c dbSNP:576060545
79 79 c, t dbSNP:538883479
84 84 c, t dbSNP:577256920
89 89 c, t dbSNP:558817324
94 94 a, c dbSNP:11544359
99 99 a, c dbSNP:566724701
100 100 a, g dbSNP:548194624
119 119 a, c dbSNP:536508549
122 122 g, t dbSNP:569213722
127 127 c, t dbSNP:777911095
132 132 c, t dbSNP:756111367
133 133 a, c, g dbSNP:767354084
138 138 g, t dbSNP:754674603
140 140 a, t dbSNP:751125107
143 143 c, t dbSNP:766023116
145 145 g, t dbSNP:200867605
146 146 c, t dbSNP:772695137
147 147 a, g dbSNP:765800238
149 149 a, c dbSNP:762238142
150 150 c, g dbSNP:776990198
152 152 -, gg dbSNP:757212098
156 156 c, t dbSNP:768851497
158 158 g, t dbSNP:760985444
159 159 c, t dbSNP:373989408
164 164 c, t dbSNP:772318835
167 167 g, t dbSNP:201920149
174 174 a, c dbSNP:377304702
186 186 c, t dbSNP:546348236
194 194 a, g dbSNP:769859276
209 209 a, g dbSNP:763952937
210 210 a, g dbSNP:781159401
211 211 c, g dbSNP:754767647
213 213 c, t dbSNP:149755644
223 223 a, g dbSNP:528202675
236 236 a, g dbSNP:560825840
256 256 g, t dbSNP:199919027
266 266 a, c dbSNP:11544360
268 268 a, g, t dbSNP:555086214
272 272 c, g dbSNP:748128814
274 274 c, t dbSNP:781038122
276 276 a, c dbSNP:768624071
280 280 c, g dbSNP:746846227
288 288 c, g dbSNP:779831481
303 303 c, t dbSNP:757995996
317 317 c, t dbSNP:750024548
321 321 a, g dbSNP:79619080
324 324 c, t dbSNP:756797339
329 329 a, g dbSNP:753326846
337 337 c, t dbSNP:764570013
344 344 a, t dbSNP:746436655
361 361 g, t dbSNP:753012648
373 373 c, t dbSNP:767865830
374 374 g, t dbSNP:367909953
376 376 c, t dbSNP:376110241
386 386 a, g dbSNP:530556235
389 389 g, t dbSNP:766684538
392 392 c, t dbSNP:763181346
394 394 c, t dbSNP:189890133
401 401 c, t dbSNP:199497690
403 403 g, t dbSNP:768481874
404 404 c, t dbSNP:544948095
405 405 c, g, t dbSNP:372039867
412 412 c, t dbSNP:549411169
418 418 a, t dbSNP:745628426
427 427 a, g dbSNP:778589030
428 428 a, c, g dbSNP:146310523
430 430 a, g dbSNP:575576320
431 431 a, g dbSNP:756592742
432 432 c, g, t dbSNP:186986959
434 434 a, g dbSNP:767804680
436 436 g, t dbSNP:755435590
438 438 c, t dbSNP:751957538
442 442 c, t dbSNP:541224696
443 443 c, t dbSNP:763201300
460 460 c, t dbSNP:773179109
467 467 a, g dbSNP:765308302
491 491 a, g dbSNP:760557285
511 511 a, t dbSNP:775535419
516 516 a, c dbSNP:200288712
519 519 c, t dbSNP:745724072
522 522 a, g dbSNP:774130913
526 526 g, t dbSNP:770578428
532 532 a, c dbSNP:748917911
533 533 c, t dbSNP:777170757
540 540 c, t dbSNP:181954619
542 542 a, g dbSNP:747582227
543 543 c, t dbSNP:781778604
544 544 a, t dbSNP:755536372
550 550 c, t dbSNP:751975953
556 556 a, g dbSNP:554685015
576 576 a, g dbSNP:200799419
581 581 a, g dbSNP:750615415
583 583 c, t dbSNP:757371606
602 602 a, c dbSNP:201280051
605 605 a, g dbSNP:753851004
610 610 a, g dbSNP:767512858
612 612 a, g dbSNP:759405037
620 620 c, g dbSNP:774149293
632 632 a, g dbSNP:770664185
633 633 c, t dbSNP:762545404
641 641 a, g dbSNP:772959139
648 648 c, g dbSNP:769311446
651 651 g, t dbSNP:747758720
654 654 c, g dbSNP:780781747
669 669 a, g dbSNP:374589338
693 693 c, g dbSNP:769299661
697 697 a, g dbSNP:753970426
702 702 c, t dbSNP:780596140
711 711 a, g dbSNP:758835778
721 721 a, g dbSNP:199761990
739 739 g, t dbSNP:750730056
740 740 a, c dbSNP:779251454
746 746 a, g dbSNP:757418816
751 751 a, g dbSNP:556949912
754 754 a, g dbSNP:764103891
775 775 g, t dbSNP:759492560
781 781 a, g, t dbSNP:370952195
793 793 c, t dbSNP:762857765
826 826 c, t dbSNP:766400004
849 849 a, g dbSNP:141976823
876 876 c, t dbSNP:13280993
900 900 a, c dbSNP:750242653
901 901 a, g dbSNP:764888332
908 908 a, c dbSNP:138847615
915 915 c, g dbSNP:376627182
916 916 c, t dbSNP:776462221
935 935 a, t dbSNP:763814813
943 943 a, g dbSNP:760317579
952 952 c, t dbSNP:551087857
969 969 a, g dbSNP:772639292
988 988 a, g, t dbSNP:200224543
993 993 a, c dbSNP:771161154
1003 1003 c, t dbSNP:749626149
1005 1005 a, g dbSNP:201161490
1008 1008 c, t dbSNP:371076039
1010 1010 -, g dbSNP:764935629
1016 1016 a, g dbSNP:748296993
1028 1028 c, t dbSNP:781072755
1029 1029 a, g dbSNP:758374701
1081 1081 a, c dbSNP:778082305
1111 1111 g, t dbSNP:563330068
1129 1129 -, ac dbSNP:147930178
1129 1129 a, c dbSNP:547700652
1131 1131 a, c dbSNP:529175130
1138 1138 a, g dbSNP:561502728
1189 1189 c, t dbSNP:138030819
1209 1209 c, t dbSNP:768296234
1215 1215 c, t dbSNP:760361488
1216 1216 a, g dbSNP:530907459
1251 1251 c, g, t dbSNP:550104943
1307 1307 c, t dbSNP:545057654
1316 1316 g, t dbSNP:577991090
1322 1322 g, t dbSNP:78830147
1412 1412 a, c dbSNP:541711087
1419 1419 a, c dbSNP:574396273
1446 1446 a, t dbSNP:775697516
1454 1454 a, g dbSNP:191183298
1460 1460 c, t dbSNP:772433275
1461 1461 g, t dbSNP:188287057
1469 1469 g, t dbSNP:537690463
1486 1486 g, t dbSNP:746249869
1494 1494 c, t dbSNP:533422664
1499 1499 -, t dbSNP:547919301
1523 1523 a, g dbSNP:774854278
1526 1526 c, t dbSNP:543834444
1615 1615 c, t dbSNP:771577552
1617 1617 g, t dbSNP:749364072
1624 1624 c, t dbSNP:557870374
1665 1665 a, c, t dbSNP:564738544
1734 1734 a, t dbSNP:184610100
1763 1763 c, t dbSNP:779620439
1779 1779 a, c dbSNP:546996646
1865 1865 g, t dbSNP:535316181
1889 1889 -, atga dbSNP:541282913
1901 1901 c, t dbSNP:376808532
1904 1904 a, c dbSNP:568059141
2026 2026 a, g dbSNP:372200548
2046 2046 a, g dbSNP:531436172
2061 2061 a, c dbSNP:563608732
2064 2064 a, g dbSNP:551823833
2093 2093 g, t dbSNP:192953720

Target ORF information:

RefSeq Version NM_003068
Organism Homo sapiens (human)
Definition Homo sapiens snail family zinc finger 2 (SNAI2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003068

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGCCGCGCT CCTTCCTGGT CAAGAAGCAT TTCAACGCCT CCAAAAAGCC AAACTACAGC 
GAACTGGACA CACATACAGT GATTATTTCC CCGTATCTCT ATGAGAGTTA CTCCATGCCT
GTCATACCAC AACCAGAGAT CCTCAGCTCA GGAGCATACA GCCCCATCAC TGTGTGGACT
ACCGCTGCTC CATTCCACGC CCAGCTACCC AATGGCCTCT CTCCTCTTTC CGGATACTCC
TCATCTTTGG GGCGAGTGAG TCCCCCTCCT CCATCTGACA CCTCCTCCAA GGACCACAGT
GGCTCAGAAA GCCCCATTAG TGATGAAGAG GAAAGACTAC AGTCCAAGCT TTCAGACCCC
CATGCCATTG AAGCTGAAAA GTTTCAGTGC AATTTATGCA ATAAGACCTA TTCAACTTTT
TCTGGGCTGG CCAAACATAA GCAGCTGCAC TGCGATGCCC AGTCTAGAAA ATCTTTCAGC
TGTAAATACT GTGACAAGGA ATATGTGAGC CTGGGCGCCC TGAAGATGCA TATTCGGACC
CACACATTAC CTTGTGTTTG CAAGATCTGC GGCAAGGCGT TTTCCAGACC CTGGTTGCTT
CAAGGACACA TTAGAACTCA CACGGGGGAG AAGCCTTTTT CTTGCCCTCA CTGCAACAGA
GCATTTGCAG ACAGGTCAAA TCTGAGGGCT CATCTGCAGA CCCATTCTGA TGTAAAGAAA
TACCAGTGCA AAAACTGCTC CAAAACCTTC TCCAGAATGT CTCTCCTGCA CAAACATGAG
GAATCTGGCT GCTGTGTAGC ACACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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