||ORF Nucleotide Sequence (Length: 1236bp)
||pcDNA3.1-C-(k)DYK or customized vector
|Tag on pcDNA3.1-C-(k)DYK
||C terminal DYKDDDDK tags
|ORF Insert Method
||CloneEZ® Seamless cloning technology
||Homo sapiens (human)
||SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
||REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from BQ707908.1, AK095047.1 and
This sequence is a reference standard in the RefSeqGene project.
On Mar 30, 2004 this sequence version replaced gi:21264354.
Summary: The protein encoded by this gene is part of the large
ATP-dependent chromatin remodeling complex SWI/SNF, which is
required for transcriptional activation of genes normally repressed
by chromatin. The encoded protein, either alone or when in the
SWI/SNF complex, can bind to 4-way junction DNA, which is thought
to mimic the topology of DNA as it enters or exits the nucleosome.
The protein contains a DNA-binding HMG domain, but disruption of
this domain does not abolish the DNA-binding or
nucleosome-displacement activities of the SWI/SNF complex. Unlike
most of the SWI/SNF complex proteins, this protein has no yeast
counterpart. [provided by RefSeq, Jul 2008].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
Transcript exon combination :: BC069196.1, AK095047.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns